LOCUS       NZ_JAEACL010000001     21612 bp    DNA     linear   CON 23-MAR-2024
DEFINITION  Bacillus halotolerans strain Nss14 C1PK5, whole genome shotgun
            sequence.
ACCESSION   NZ_JAEACL010000001
VERSION     NZ_JAEACL010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus halotolerans
  ORGANISM  Bacillus halotolerans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 637969)
  AUTHORS   Douka,D., Papadimitriou,K., Venieraki,A. and Katinakis,P.
  TITLE     Genome sequence of Bacillus halotolerans PK5 (Nss14)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 637969)
  AUTHORS   Douka,D., Papadimitriou,K., Venieraki,A. and Katinakis,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-NOV-2020) Crop Science, Agricultural University of
            Athens, Iera Odos 75, Athens 11855, Greece
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 60.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016767285.1-RS_2024_03_23
            Annotation Date                   :: 03/23/2024 01:56:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,125
            CDSs (total)                      :: 4,048
            Genes (coding)                    :: 3,918
            CDSs (with protein)               :: 3,918
            Genes (RNA)                       :: 77
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 55
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 85 of 130
            Pseudo Genes (incomplete)         :: 68 of 130
            Pseudo Genes (internal stop)      :: 30 of 130
            Pseudo Genes (multiple problems)  :: 45 of 130
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:29:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 133396
            Orig. end                         :: 155008
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAEACL010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(76..90)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(168..3854)
                     /locus_tag="I5F14_RS00765"
                     /old_locus_tag="I5F14_00765"
     CDS             complement(168..3854)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="I5F14_RS00765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00765"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_069486788.1"
                     /transl_table=11
                     /translation="MKKKKLSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQAHQNPLEAWKSIVENPDKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVITYGPDRNIGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQKTERFIEYAKQYTD
                     FPFFVTLTKEDGVYTAGRFLHAKDIGRQTEHDQWKPAVWNERTSAFAIPQGTMGSRWDG
                     QKKWNLHMIDEETGESIEPRLSVLGIEDEIGTVRIPYFSNEGNRVLERDLPIKKLALDN
                     EDVYVTTVFDLILANYGVNRGIGEKSACSYDDPEPFTPAWQEQVTGIKKEAVIKIAREF
                     AQNAIDTEGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPVSDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFDKNGIDLYKEAEKAGAKTTKDVADYVARQLQEKKLKFAIEDP
                     DNEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLADEVDMKPVKEAVAAPLLHDTMQEMAQPLGKIKDWSKGECEAV
                     PGKTMPNIQVVERDYKQIFHKMTALGPNAALKPNGTKGMSWSIADEYESLKKRLGEVTS
                     DSVAKGCPNISEAKQAAEAVLTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIRDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3920..3935)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    4000..4009
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(4072..4548)
                     /locus_tag="I5F14_RS00770"
                     /old_locus_tag="I5F14_00770"
     CDS             complement(4072..4548)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="I5F14_RS00770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00770"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_202646702.1"
                     /transl_table=11
                     /translation="MNQCDYLFFLKQLPMFNEVPLSIVETLLNNGTFIGGSCDQDLSFL
                     HSQSIYIVLKGSIRFIDSRLPEGSQTVALWEKGDVFPIDQKGGMFLSPFISVRTSEDIL
                     MLNIPFYLLKKIMSYYPQLQMNFLVMLQQNVFFSYELFLRYMHRSQDENAEPDS"
     misc_feature    complement(4606..4621)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4692..5411
                     /locus_tag="I5F14_RS00775"
                     /old_locus_tag="I5F14_00775"
     CDS             4692..5411
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="I5F14_RS00775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00775"
                     /product="YwiC-like family protein"
                     /protein_id="WP_069486787.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFCLGMVKGGAILWHIPLFLGWLFLYLA
                     VYPVTLALKKKQINPYQKWIFSYSFPACSFLLAAVIHKPSFIWLAFSLLPLFLIHVYYA
                     RQKNERALLNDFAGVLFFCTGGLASCWLGTETLDGWAWFIFAQSALFFIGSSFYVKSVI
                     REKNNRVFACWSWGYHLILPLLSAAFGAGWAVLAFIPSSLRAWFFHGKKWPVQTIGILE
                     IVNACFFFAIMCIWLTR"
     gene            complement(5444..6160)
                     /locus_tag="I5F14_RS00780"
                     /old_locus_tag="I5F14_00780"
     CDS             complement(5444..6160)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="I5F14_RS00780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00780"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_069486786.1"
                     /transl_table=11
                     /translation="MNFLSVRTSDKDLISSDLHQLLESISTKRKIKKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTADGKDLTLRICQQNDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKSRLEKELIHNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VNRSDGILINIALTNQDLAKFCAAARESVNRMLGDLRKQGVISIEDSGKIVLHQRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6271..7458)
                     /locus_tag="I5F14_RS00785"
                     /old_locus_tag="I5F14_00785"
     CDS             complement(6271..7458)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="I5F14_RS00785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00785"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_069486785.1"
                     /transl_table=11
                     /translation="MINRQHFQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARIIFMISFILLLFPVFWISMADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAITTFAAPVIAQAAGWKSTVQ
                     MYMVLLALFALLHFFFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEQFDLSPADAGLRTAGFIAVSTLLRPAGGWLADKVSPLRILMFVFAGLTLS
                     GVILSFSPTIGIYAFGALTVAVCSGIGNGTVFKLVPFYFSKQAGIANGVVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVIVIWMYWQERMKTHTERSGHSVN"
     misc_feature    complement(7523..7538)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    7535..7550
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.43"
                     /tool="antismash"
     misc_feature    7541..7554
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.45"
                     /tool="antismash"
     misc_feature    7542..7555
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    7543..7556
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="I5F14_RS00790"
                     /old_locus_tag="I5F14_00790"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="I5F14_RS00790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00790"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_202646703.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIISIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRVDLENFRVPFDVWYSETSLYQNGKIDKALDALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLVNVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSPIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /locus_tag="I5F14_RS00795"
                     /old_locus_tag="I5F14_00795"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="I5F14_RS00795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00795"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="I5F14_RS00800"
                     /old_locus_tag="I5F14_00800"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="I5F14_RS00800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00800"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 1.4e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="I5F14_RS00800_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="I5F14_RS00800_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="I5F14_RS00805"
                     /old_locus_tag="I5F14_00805"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="I5F14_RS00805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00805"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="I5F14_RS00810"
                     /old_locus_tag="I5F14_00810"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="I5F14_RS00810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00810"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_202646704.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1078.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 3.3e-30,
                     bitscore: 99.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.3e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.2e-45, bitscore:
                     150.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 5.5e-07, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.4e-23, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.2e-10, bitscore:
                     37.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-09, bitscore: 33.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMYPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGRNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSPLVHKLWKAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_I5F14_RS00810_Subtilosin_rSAM_RRE.1"
                     /evalue="1.40E-31"
                     /identifier="RREFam018.1"
                     /label="I5F14_RS00810"
                     /locus_tag="I5F14_RS00810"
                     /protein_end="97"
                     /protein_start="5"
                     /score="99.7"
                     /tool="antismash"
                     /translation="MYPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="I5F14_RS00815"
                     /old_locus_tag="I5F14_00815"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="I5F14_RS00815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00815"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_024123213.1"
                     /transl_table=11
                     /translation="MSPAQRKMLLYILSFIFVIGAVVYFVKSDYLFTLISIAIAIIFGM
                     RARKADSR"
     gene            11783..12502
                     /locus_tag="I5F14_RS00820"
                     /old_locus_tag="I5F14_00820"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="I5F14_RS00820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00820"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_069486784.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILENVDLQLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGHFTLCGIEADAGMPQKTSDELKTRRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFNSLAEEFHFSQYTNRRISELSLGNRQKVVLMTGLLLGAPLFILD
                     EPLVGLDVESIEVFYQKMQAYCKAGGTILFSSHLLDVVQRFCDYAAILHHKQIRKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13808
                     /locus_tag="I5F14_RS00825"
                     /old_locus_tag="I5F14_00825"
     CDS             12495..13808
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="I5F14_RS00825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00825"
                     /product="hypothetical protein"
                     /protein_id="WP_059353715.1"
                     /transl_table=11
                     /translation="MNNLFPILSLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESTLGKTYITLALLFMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSAVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLYWLGRFSFFTVYSIIFGVLLSNLFVKKRR
                     TALLLHAAAFTCVCFSAALMPAVTIPLCAIHMLWAIVIDFPSFLQAPQQQSKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMGAFSGFFSFQMMNTGIADQHVVYIVISALLLIC
                     SPIALLYSLEKNDRILLITLPIKRRTMLWAKYRFYSGLLAGGFILIAMIMGLISGRPIS
                     LLTFLQCMELLLAGAYIRLISDEKKPSFSWQTEQQLWSGFSKYRSYVFCIPLFLATLTG
                     TVISLAVIPIAGLIIVYLLQKQDGGFFDTSGKRERLGS"
     gene            13798..14961
                     /locus_tag="I5F14_RS00830"
                     /old_locus_tag="I5F14_00830"
     CDS             13798..14961
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="I5F14_RS00830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00830"
                     /product="insulinase family protein"
                     /protein_id="WP_202646859.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4.2e-06,
                     bitscore: 22.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLTTDQFSTISIAASFLKPIESAAEPEEETIYFYGAAAHQK
                     QNIIDTFGYAAGRRFMYSANLFFDRQLKTYGTRMIHPLYAEGFHTDAVLNTFVDMSSFP
                     ASLSASAAEKAKAELLLKMEKTFADPFSYSAARLAEEAFGNPMYGTAMFGRKDKLMAVH
                     PKRFLDASEFIADLFSQQKQLNILGNIQSCDVQGHAPQASAVSAVRKPVNQDIFETETR
                     STAGPSVMTLGFDCGDMKDVRDYLAMQLIDGLLGKYGHSALFRHFREKDLAVYHVITRY
                     DIMNNMLLVSVCTDQLHENEIPPRVLEAVSRFHADEPELKKAQQFLINEILLQFDSPEG
                     LLAYMGILRRFSCKKEDLLDSISAVTCRDLLQFIKNLTYIGAHVVRG"
     gene            14967..16244
                     /locus_tag="I5F14_RS00835"
                     /old_locus_tag="I5F14_00835"
     CDS             14967..16244
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="I5F14_RS00835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00835"
                     /product="pitrilysin family protein"
                     /protein_id="WP_202646705.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 3.4e-13, bitscore:
                     45.2, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 8.3e-07,
                     bitscore: 24.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKEAFFQQLDERTDIRYTDKGMKIFRLQFPRAHLRLCNVKTGFG
                     SQDVRLQSETGGRMLPYGTAHFLEHLLFWHNGRNLYTDFFEHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDEQIIAQEKAVITSEIDTALLNHQLHYHYQLIQMLS
                     PASPAAIFPAGRKRDIEALSICDLQEAYAAAYQPHRMTLFLIGGPEDAETLLPSQLRLE
                     KCSGSRSDRKIVPACPPLSSKEVKGDLERPEDTWTGIQIGALPGENGLLTLKLYWDIAS
                     RILFHMDSPFFQEIRQTYRLNIQSLSADVHLSEDGGFLILHSKGAHSSAYIDVASYYIT
                     QQKNRTEAWLEYGKDSLVNAIIYDSDYARKCFEWAAECEQYDCSFLGLYRTIQQMNSHD
                     FLALIEAMVSSNKAVIHVPQKEVMRQ"
     gene            16241..16942
                     /locus_tag="I5F14_RS00840"
                     /old_locus_tag="I5F14_00840"
     CDS             16241..16942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="I5F14_RS00840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00840"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_202646706.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLAAMAAYSFGWFHSGAEAAGQYVQLINNDAARL
                     GLLACAASVLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQHRKLCSRYADDVK
                     LLRDSYRGIRQSYVMAAVLYQVIVFGCMFEIVKAVPFSFHTSPAVTMGLAVLLILYLLF
                     YLRTYLLQLFQHGNLFRKVLVGVLTGAGIWWMLSFTISELLFLIILAAIQQIGSFIYKR
                     FSYRSPASLDL"
     gene            complement(16949..>17303)
                     /locus_tag="I5F14_RS00845"
                     /old_locus_tag="I5F14_00845"
                     /pseudo=""
     CDS             complement(16949..>17303)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="I5F14_RS00845"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="I5F14_00845"
                     /product="YncE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VMNGELGPKGVTEISLSPLSRGWL"
     gene            complement(17481..18839)
                     /locus_tag="I5F14_RS00850"
                     /old_locus_tag="I5F14_00850"
     CDS             complement(17481..18839)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="I5F14_RS00850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00850"
                     /product="YncE family protein"
                     /protein_id="WP_044159815.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAEAAQDCLCFCEEETSREAMFQAPIELPEGFVVD
                     PAEAVANVTWNADSLSCVSERCLIQTGPEPDEIGVQFAVRLQGTVTLLVSVSPVRNQYG
                     QGEGAVSVIHNVEIDQVVYYSDEPDDCPDVSDITIENLVVVPPFYGSPLSVTGTIVLVP
                     APEPEPVYAFTANPDDQSVSVIDTNTHTVVTTISLPYQPTRIEKAPDNTSVFVLHYYDR
                     VISVISQDTLSVTASILLDQPPESISFIPGHEFFYVVAGGAINVIGIETLTVERSIPFE
                     GFDVAIDPNGLFAYLLGFGSVQRLDLNTGEVTGTIERDLIVNALETGWPERYLYVLEQE
                     FFFNYLTVIDLNTFTISSTQELEYEGEYGMFKSGSGVYLFDDFTHNLYSVSPSGAGVIG
                     NLPQLARDIAFTPNGEFLYATNFIEQSITVYNTDDYSVETVISLGVSPSDIAI"
     misc_feature    19019..19035
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19068..20213
                     /locus_tag="I5F14_RS00855"
                     /old_locus_tag="I5F14_00855"
     CDS             19068..20213
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="I5F14_RS00855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00855"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_202646707.1"
                     /transl_table=11
                     /translation="MTSVISSSSVGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLENMRIEEQPRLSDLLLEIDKKQARLTGVLDYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKEHTAYNIRLLQCHSLFATNFLDLKQYEDAISHFKKAYTMAESEKQPQLMG
                     RTLYNIGLCKNSQEQYESAITYFKRAISVFEEANILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGIDYSKEAGDIIYLSEFEFLKSLYLSGPDEEAIQKFFDFLESKMMYADLEDFA
                     LDVAKYYHGRENFQKASAYFLKVEQVRQLIQGGVRLYEIEV"
     gene            20197..20316
                     /gene="phrF"
                     /locus_tag="I5F14_RS00860"
                     /old_locus_tag="I5F14_00860"
     CDS             20197..20316
                     /codon_start=1
                     /gene="phrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="I5F14_RS00860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00860"
                     /product="phosphatase RapF inhibitor PhrF"
                     /protein_id="WP_059292327.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATNIANAPTHQMEVAQRGMI"
     gene            complement(20426..21298)
                     /gene="speB"
                     /locus_tag="I5F14_RS00865"
                     /old_locus_tag="I5F14_00865"
     CDS             complement(20426..21298)
                     /EC_number="3.5.3.11"
                     /GO_function="GO:0008783 - agmatinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="speB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391629.1"
                     /locus_tag="I5F14_RS00865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_00865"
                     /product="agmatinase"
                     /protein_id="WP_044159819.1"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIASRPEWEEADAILYGMPMDWTVSYRPGSRFGP
                     GRIREVSIGLEEYSPYLDLDLADLNFFDAGDIPLPFGNPQKSLDMIEEYVDSILEKGKF
                     PMGMGGEHLVSWPVMKAMYKKFPDLAIIHFDAHTDLRVDYEGEPLSHSTPIRKAAELIG
                     PENVYSFGIRSGMKEEFEWAKENGMHISKFEVLEPLKEVLPKLAGRPVYVTIDIDVLDP
                     AHAPGTGTVDAGGITSKELLASVHEIARSEVNVKGADLVEVAPIYDHSEQTANTASKII
                     REMLLGFVK"
ORIGIN
        1 cctgatcctc ccattgcttc ggatagccga tacctggctt tgtttctaca ttattgaaat
       61 acatatattc ggcaccggaa cggtttgtcc acgtgttttt gcaagtgacg ctgcacgtgt
      121 ggcagccgat gcatttatct aagttcatga ccattccgat ttgcgcttta atcttcaagc
      181 caatcgacct ccttcagctt gcggatgacc acattcagat cgcgctgatt ccccgtaggg
      241 ccatagtagt taaagccgta gctgagctgg gcatagccgc cgatcatctg tgtcggcttg
      301 acgtgaatcc ttgtcggact gttatgggtg cctccgcggt tattggtcag ttttgtgccg
      361 ggcacgttga tgtggcggtc ttgggcatga tgcataaacg ccattccttt aggaatacgg
      421 tgagaaagaa cggctctcgc tacgacaacg ccatttcggt tgaagcattc aatccaatcg
      481 ttgtctcgga tatctgtgtc ctctgcatca tctttattca tccacactgt cggcccgccg
      541 cgaaatagcg taagcatcgg cagagaatca aaatacatgc tgtgcacgga ccatttgtta
      601 tgcggcgtta aataattgag aacgatttct ttgccctctt gatcaggccg tttgcttaag
      661 aaagggcgat gctggaggat cggtttaaag gtcgccatcg tttccccgaa ctccatcatc
      721 agctcatgat cgacataata ggattgtctg cctgtcagcg tacgccaagg gattaatttt
      781 tccacatttg tcgtaaacgg cgaatacctg cgcccgcctt tttccgagcc tgtaaatgcc
      841 ggagatgtga tcaccgtttt gggctgagcc gtgatttgtt cgaacgtaaa gcattcttcc
      901 tcccgctctt cagccagatc tttcagcttc agatttgtga tgtcttcaag cgattcccat
      961 gcttttacgg caacttttcc attcgacgtg gacgaaaggg ttaaaacggc ttctgccgcc
     1021 tgcttggcct cgcttatatt tggacatccc tttgcgacac tgtctgaggt gacttctccc
     1081 agcctttttt tgagtgattc gtattcatcg gcaatcgacc agctcatgcc ttttgttccg
     1141 tttggtttta aggcggcgtt tgggccgagc gcagtcattt tatgaaagat ttgcttgtag
     1201 tccctttcaa caacttgaat gttcggcatc gttttccccg ggacggcttc gcattcgcct
     1261 ttgctccagt ccttaatttt tccgagaggc tgggccattt cctgcatggt gtcatggagg
     1321 agcggtgcgg cgacagcttc ttttaccggc ttcatatcaa cttcgtccgc gagatcggag
     1381 acggcttttg ataaagcctt gaaaatatcc cagtctgact tcgattccca aggagccgaa
     1441 atagccgggg caaaggggtg gataaacgga tgcatatcag tgctgctgag atcgtgtttt
     1501 tcataccatg tcgccgccgg aagcacgata tcggaataca aggcggtacc ggccattcgg
     1561 aaatcgagat tgattaacaa atcgagcttt ccttccggtg cctgctcgcg ccatttgatt
     1621 tcttcaggac ggatgctgtc gctgtcgtca ttcatcaagc cgttcgtcgt tcccaagaga
     1681 tgcttgagaa aatattcatg cccttttccc gaactggaga tcagattcgc tctccacacg
     1741 aacaggtttc tcggaaaatt cgcttcattg tcaggatctt caatggcaaa tttcagtttt
     1801 ttctcttgaa gctggcgggc cacatagtca gcaacatctt ttgttgtctt cgcccccgct
     1861 ttttcagctt ctttgtacag gtcaattccg tttttatcaa atgtcggata agacggaagc
     1921 cacccgagtc ttgccgccag cacattgtag tcggcgtgat gcttgtagcg ggaggatgcc
     1981 gcgatcggag atgctaagtc actgaccggc tgatcctcgt agcgccactg gtcagtcgca
     2041 aaatagaaaa aggaagtgcc gttttgcagc tttggcgccc cctcccaatc cttagcgttg
     2101 gcgatcgtct gccagccttc agcagggcgg agtttttcct gtcctacata atgagcccag
     2161 cctccgccgt ttacgccttg ggcgcctacc agtaatacga gatttaatac tgcccggtag
     2221 atcgtgtcag agttgaacca gtggttgatc cccgccccta cgataatcat ggatcggccc
     2281 tctgtatcga ttgcattttg ggcaaactct ctggctatct taatgacggc ttcttttttg
     2341 atccctgtca cctgctcctg ccaggctggc gtaaacggtt caggatcgtc atacgagcag
     2401 gctgatttct ccccgatccc ccgattcacg ccgtagttag ccaaaatcaa gtcaaatacg
     2461 gttgtgacat agacatcttc attgtccagg gccagttttt ttataggcag atctcgctct
     2521 agcactctgt ttccctcatt tgagaaataa gggattcgaa ctgtgccgat ttcgtcctct
     2581 atgccgagca ccgaaagccg gggttcaatc gattcgcctg tttcttcatc tatcatgtgc
     2641 aggttccatt tcttttggcc gtcccagcgg gagcccattg ttccttgcgg aatcgcgaat
     2701 gcgcttgtac gttcattcca caccgcaggc ttccactgat catgctccgt ctgccgcccg
     2761 atgtcctttg cgtgaagaaa acgcccggcc gtatacacgc catcctcttt agttagagtg
     2821 acaaagaacg ggaaatccgt gtattgcttt gcgtactcta tgaaacgctc tgtcttctga
     2881 ttaacgtaaa actcctgcag gatcacatgc cccatcgcca tcgcaagcgc gccgtctgtt
     2941 ccttggcgga tgctcagcca gtcatctgca aatttagagg attccgcgaa atcggggctg
     3001 attgagatga ccttagcgcc tttatagcgg gcttctgcca aaaaatgcgc atccggcgtc
     3061 ctcgttaacg gcacattgga gccccatgtg atgatatagc ctgagttgta ccaatcactg
     3121 ctttccggga cgtctgtctg gtcgccccag atttgcggcg atgccggggg aagatccgca
     3181 taccaatcat agaaactgag catagggccg ccaatcaaag acataaaccg cgagcctgac
     3241 gcatggctta tcatggacat agccggaatc ggagaaaacc cgatattccg gtcagggccg
     3301 tatgttataa ccgtatacag cagagaagca gaaatcagct tcagcacctc cggccattca
     3361 gcgcgcacaa agccgccctt tccccgcgcc tgtttatagg acttcgcttt atccggattt
     3421 tcaacgatcg atttccatgc ttccaaaggg ttttgatgag cctgcaatgc ttcccgccac
     3481 aaattgatca ggacaccgcg cacgtatgga tatttgacac gcagcgggct gtagatatac
     3541 caggaaaaac ttgccccgcg gggacagccc cttggctcga agtcaggcat atcagggccg
     3601 gttgaaggat aattcaaatt ttgcccttcc cacgtgacga tgccgttttt cacataaata
     3661 ttccagctgc aagatcccgt gcagttgact ccgtgggtgg agcggacaac tttatcgtac
     3721 tgccatctgt ttctatatac attctcccaa tcgcgatctt cgcgggtggt ttggctatgt
     3781 ttatttgaat ggtgttcgat aggagagaaa tagttcaatc tcctaaacaa cggactcaat
     3841 ttctttttct tcatgagagt tcactccttc cgagtcaggt gatgctaagt tcactataaa
     3901 cagagaaagc gtatttcctt gtgaactatg tcacacactc cccttttttc acagaaagtt
     3961 cacatgagga agaaggaagg gactttcaca ggatgtgatg aaggcggcgt tcaggcagga
     4021 cgcctgagtc attagccgtc tttcattcaa agatcaaaaa cccggttcct tttaggaatc
     4081 gggctcagcg ttttcatcct gagatctatg catgtatcgc aaaaacagct cataagagaa
     4141 aaagacattt tgctggagca tcaccagaaa attcatttgc agctgcggat aataggacat
     4201 gattttcttt aataagtaaa aagggatatt gagcataaga atgtcttcgg atgttcggac
     4261 tgaaatgaat ggagataaga acatcccgcc tttttgatca atgggaaaca catcgccttt
     4321 ttcccacagc gccacggttt gcgacccttc aggcagcctg ctgtcaataa aacgaatact
     4381 gccttttaat acaatataaa tggattgaga atggagaaaa gatagatcct gatcacatga
     4441 accgccgata aacgtcccgt tattcagcaa tgtttcgaca atggatagag gcacttcatt
     4501 aaacatagga agttgtttca aaaaaaataa atagtcacac tgattcatag ggaagcctcc
     4561 tgtgctaagg atagctttag tgtagcccgg ccgatccatg acagcagtga tgtatttcac
     4621 agatgatatg atgaatgtca cttattggcg gtatttttgc ttttataatg aaacaagaaa
     4681 ggagtgtttc gatgaaggcg cttattccga agcagcacgg cgcttgggcc atgctgctga
     4741 ttccgttttg cctcggtatg gtgaagggag gagcgattct ttggcatatc cccctatttt
     4801 taggctggct ttttctttat ttagctgttt atcctgttac gctggcatta aaaaagaaac
     4861 aaatcaaccc ctatcaaaag tggatatttt cttacagttt tccagcctgc agctttttgc
     4921 ttgccgctgt catccataag ccgtctttta tctggcttgc cttttctttg ctgccgctgt
     4981 ttctcattca tgtgtattat gcccggcaaa aaaatgaacg agcgctgctg aatgattttg
     5041 cgggcgtctt attcttttgt acaggcggac tcgccagctg ctggctgggg acggagactc
     5101 ttgacggctg ggcatggttt attttcgcac aatctgcttt gttttttatc ggaagttcat
     5161 tttatgtgaa gtcggtgatc cgggagaaga ataatagagt atttgcctgc tggtcgtggg
     5221 gctatcacct gatcctcccc ttactttccg cagcttttgg agcgggctgg gccgttctcg
     5281 cctttatccc cagcagtttg cgtgcatggt tttttcatgg aaagaagtgg cctgttcaaa
     5341 cgatcggcat tcttgaaatc gtcaatgcgt gcttcttttt cgccatcatg tgtatttggc
     5401 taacaagata aaaacaagga cacattgctg tccttgtttc ctcttaatca atattgcaaa
     5461 tctctaacgg gcaattttcg cactcaatct cacaccgtaa atagtcccgc tgatgcagta
     5521 caatctttcc ggaatcctct attgaaataa ccccttgttt gcggagatca cccagcatgc
     5581 ggttgacgct ctctcttgca gccgcgcaaa atttcgccaa atcctggttt gtcagggcaa
     5641 tgttaatgag aatgccgtca ctccggttca ccccatagct gtttgacaag cggatgaggg
     5701 tggagtagag cgcccctttt ttgccatgaa gaagaaggtc tctgattttg gattgaattt
     5761 tgcgcaaatg ggtgctcatc catttcataa attcaaatgt caaagcaccg ttgtggataa
     5821 gttccttttc aagtctgctt ttattgatga cgagcacttc gccatcctcc agcacttttg
     5881 cactgagcat atatctcggt tcttctgtga aaagtgttaa ttcaccgaca atatcatttt
     5941 gttggcagat tcttagcgtc aggtctttgc cgtcagccgt cagcttcccg atttcaatga
     6001 gtcctgactg aatcagataa agctcttctg catccattcc ttctcgaaac aggtatgtgt
     6061 gttttttgat ttttcttttt gtactgatgg attccagcaa ttgatgaaga tcactggaaa
     6121 taagatcctt atcagatgtt cgaacagaga gaaaattcat gagctcacct cgaagaaaag
     6181 tcacgttgtg tatctattgt aacgtgaaat catttgcgct tttcagaaaa aacttacaat
     6241 ctcgtgaatt ccccaatcgc cggcggcccg tcagtttacg ctgtgcccgc ttctctctgt
     6301 atgtgttttc attctttcct gccaatacat ccatatgaca atgacaaagc ttgctaacgc
     6361 gacttccgaa agcgccataa atccgatggc gtattgtccc gtcgcctgaa atacactcgc
     6421 caggatcagc ggagggaaaa agccgcctaa tccgcccatg gcagacacga ctccgttggc
     6481 gattcccgcc tgcttagaaa aatagaaagg aaccagttta aaaaccgtcc cgtttccaat
     6541 cccggagcac accgcaaccg ttaacgcccc aaaggcgtaa atgccgatcg tcggcgaaaa
     6601 cgacaggatg acgcccgata atgtcaagcc ggcaaagaca aacatcagga tgcggagcgg
     6661 actcacttta tcagccagcc acccgcccgc cggcctgagc agcgtggata cagcaataaa
     6721 acctgccgtc cgcagcccgg catccgcagg actcagatca aactgctcaa caagaaagtt
     6781 tggcagatag attgtaaaag cgacaaaggc gccaaacgta ataaaataaa agagactcag
     6841 aaaccacagc acatgatttc ggtaaacggc tttgatttga gtctttacgg acaccttcac
     6901 tttcttctca tgccggtcac cgaagaaaaa gtgcagcaaa gcaaataaag ccagcagaac
     6961 catatacatt tgcaccgtac ttttccaccc cgccgcttga gcaatcacgg gagctgcaaa
     7021 tgtagtgatc gcggttccga tattcccggc accgtaaata ccgtttacaa cgccatgttt
     7081 ttctttagga tagtacttcg gaagagatgt aaccccaatg gaaaaaacgg ctcccccaat
     7141 ccctaagaaa aaaccgcccg cgattaaatc aaacagggaa tctgccatac tgatccaaaa
     7201 tacagggaat aaaagcaata taaagctaat cataaaaatg atccgcgcgc caaacctgtt
     7261 ggtcaaatac cccagcggaa tgcggagaag cgatcctaat ataacgggta tggccgttac
     7321 cagggagatt tcgcctttgc tcaaatgaat atctaatgtg atttgggaaa taagtgacga
     7381 aatcagcacc caaaccataa accctgccac caagcttaat gactgcagcg ataattgaaa
     7441 gtgttgacgg ttaatcattc ggcttgcccc tttcactgat tcaataatca gccttatcat
     7501 acaaaaactc ggcgaagaag attgtgaact atatcacacg attttttaac aaaaaaagga
     7561 caaagccctc tggctttgtc ctttcagctt gattacattt tttcaggagc cgatacgcca
     7621 atcaattgaa gcgcgttgtt cagcgtgatt tgcgttgctt tcattaaagc taagcgcgca
     7681 cggcttttct cttcgttttc agggtcgatg actttctccg cattgtagaa gctgtgcaga
     7741 gctgaagcca agtcataaat atagttcgtc acacggtgag gaattcgttt ttccgccgct
     7801 tccgccactg cctctgggaa accgccgatt gttttcagca gatcatattc tttttctgat
     7861 tgaatagggc tgaaatcaag atctgccgcc ggcttaagtc cttgctcttc cccttggcga
     7921 agcatgctgc aaatgcgggc atgtgcgtat tgcgcataat atacagggtt ttcgttagat
     7981 gttgatacag caagatccaa gtcaaaatcc atatgcgtat cagcgctgcg catcgcgaag
     8041 aaataacgca cggcatcaag gccgacttcg tcaatcaggt cgcgcatcgt taccgctttc
     8101 cccgtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgcac gagctgaatg
     8161 atttctactt ccaacgttcc tttttcatag ccaagtgctt cgattgccgc tttcatacgc
     8221 gggatgtagc cgtggtggtc ggcgccccat acgttgacca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatggtaggc gatatcagga agcaggtatg tgtatgtgcc gtcctttttg
     8341 atcagtacgc ggtctttgtc atctccgaac gttgtggaac ggaaccaggt cgcaccgtct
     8401 tcctcataga catggccttt ctcacgcagc gcgtccagcg ccttatcgat ttttccgttt
     8461 tggtacagtg atgtttcaga ataccacacg tcaaacggca cgcggaagtt ttccaagtct
     8521 acgcgaagct tctccagctc gtatttcaaa ccgtactcac ggaaaaatgc gaggcgttcg
     8581 ctttcttctt cgttgacgaa acggtcgccg tattcctcag cgagacgctt tccgattgaa
     8641 atgatatcct caccgcggta gccgtcctcc ggcatcggtt tttccaatcc gagcgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggctcacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg tttgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gcctttcctt tatcaaaatg agcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccagctgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttaa tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa attatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtatccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt attcagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag aaatgaattt ccgatgccgc
    10621 tccacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 ctaacggaac actcatgcga aaagagagtt tggagctttt gaaggcttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcgga gcgaaggcgt tctcttacaa ttgggttgac gatttcggaa
    11161 gaggcagaga tattgtccat ccgacgaaag atgccgaaca gcaccgcaaa tttatggagt
    11221 acgagcaaaa tgtcattgat gaatttaaag atttgatccc gatcattccg tatgaaagaa
    11281 aacgtgcggc gaactgcggc gccggctgga aatcaattgt gatcagcccg ttcggagaag
    11341 tacgcccgtg cgcactcttc ccgaaggaat tttcattggg aaatatattt catgattcat
    11401 atgaaagcat ctttgactcc cctcttgtcc ataaattgtg gaaagcgcag gcgccgcggt
    11461 tcagcgagca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaaggact gaactctaac aaatatcacc ggaaaaacat ttgctcctgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa caatttgtca ccagcacaaa
    11641 gaaaaatgtt actgtatatc ctttcattta tttttgtcat cggcgcggtc gtctacttcg
    11701 taaaaagcga ttatttgttt acgctgattt ctatcgccat cgccataatt ttcggtatgc
    11761 gcgcgcggaa ggctgactca cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaaaacgt ggatttacaa ttagaaaaag gcgccgttta
    11881 cggactgctt ggggtaaacg gcgccggaaa aacaacgctg atcaatacgc tgacaggggt
    11941 aaaccgcaat ttcagcgggc actttacgct gtgcggcatt gaagcggatg ccggcatgcc
    12001 gcagaaaaca tcagatgagc tgaagacccg ccgctacttt gctgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt ttctttcgtt cattctttgt atcagaaaga
    12121 tttctcagag cagcaattta acagtttggc agaggaattt cacttttccc aatacacaaa
    12181 ccggagaatt tccgagctgt ctctcggcaa caggcaaaag gttgtgttga tgaccgggct
    12241 attgctcggg gctcccctgt ttattttgga tgagccgctt gtcggcttgg atgtggagtc
    12301 aatagaggtc ttttatcaga aaatgcaggc gtattgcaag gcaggcggaa cgattttgtt
    12361 ttcttcccat ttgctcgatg tggtgcagag attttgtgat tatgcggcca ttcttcatca
    12421 caaacagatc cggaaggtca ttccgattgg agaggagact gatcttcggc gtgaattttt
    12481 tgaggtgatc ggccatgaat aacctgtttc cgattctgtc attgctgttc aaacagcttt
    12541 acggccgcca aggaaaaaaa gacgccattc gcatcaccgc agggcttgcc gttttggcct
    12601 tgtttgaaat cgggctgatc cgccaggcag gcattgatga atcaacctta ggaaaaacat
    12661 acatcacgct tgcgcttctg tttatgaatg cgtacatggt gtttctctct gttacatccc
    12721 aatggaagga atcttacatg aagctgagct gtctattgcc gatctcttcc cggagcttct
    12781 ggctcgctca gagtgcggtt ttgtttgttg atacttgctt gagaaggacg ctgttttttt
    12841 tcatattacc gctgttctta ttcggaaacg gaacgctgtc aggagcacaa accctgtatt
    12901 ggctcggcag attttcgttt tttactgtct attcgattat tttcggcgtt ttgttaagca
    12961 atcttttcgt caaaaaaagg agaacggcac tcctgctgca tgcggcggca ttcacctgcg
    13021 tgtgcttcag tgcggctttg atgcctgccg tgacgatccc gctatgtgcg attcatatgc
    13081 tctgggctat tgtgattgac ttcccttcat tcttgcaggc gcctcagcag cagagcaaaa
    13141 tgcattcttt tatgcggaca tcagaatttt cgttttataa aagagaatgg aaccggttta
    13201 tttcctccaa agcgatgctg ttaaattata ttgtgatggg ggcattcagc ggcttctttt
    13261 cgtttcagat gatgaacacc ggcattgccg atcagcatgt cgtctatatc gtgattagcg
    13321 ctctcctgct gatctgctca ccgattgctt tattgtattc tcttgagaaa aatgaccgga
    13381 tactgctgat cacgcttccg attaaacgca gaacgatgct ttgggctaaa tatcgctttt
    13441 attccggttt attggccggc gggtttattt tgattgccat gataatgggc ttgatcagcg
    13501 gccggccgat ttcacttttg acttttttgc agtgtatgga attgctgctg gcgggggctt
    13561 atattcggtt aatttcagat gaaaaaaagc cgtccttcag ctggcagacg gagcagcagc
    13621 tctggagcgg tttctctaaa taccgttcct atgtattttg tattcctctt tttttagcta
    13681 ctttaacagg cactgttatt tccttggcag tcattccgat tgccgggctg atcattgtct
    13741 atttactgca aaaacaggat ggtggtttct ttgatacaag cggaaaaaga gaacggcttg
    13801 gaagttaacc tgctgacgac tgatcaattt tcaaccatct cgatcgccgc gagctttctg
    13861 aagccgatcg aaagcgcggc ggaacctgaa gaagaaacga tctattttta tggcgcggct
    13921 gcacaccaga agcaaaacat catcgacact ttcggctatg ccgccggccg ccgcttcatg
    13981 tattcagcaa atctcttttt tgaccggcag ctgaaaacgt acgggacccg catgattcat
    14041 ccgttatatg ctgagggatt tcatacagat gctgttctga acacctttgt tgacatgtcc
    14101 tcctttccgg cttctctttc tgccagcgca gcggaaaagg caaaagccga actgctgctg
    14161 aaaatggaaa agacattcgc tgacccgttc tcctattcag cagcccgtct ggcggaggaa
    14221 gcctttggaa acccgatgta cggcactgcc atgtttggcc ggaaagacaa gcttatggct
    14281 gtacatccta aacgttttct ggatgcgtcg gaatttattg ctgatttatt ttctcagcag
    14341 aaacagctga acatattagg aaacatacag tcatgtgatg ttcagggaca tgccccacag
    14401 gcgtccgccg tgtctgctgt aagaaaaccc gtgaatcagg atattttcga aacagagaca
    14461 cgcagcacag caggtccgtc tgttatgaca cttggctttg actgcgggga catgaaagat
    14521 gtccgcgatt atttagccat gcagctgata gacggattgc tcggcaaata cggccattcc
    14581 gctttatttc ggcattttcg cgaaaaagat ctggccgttt atcatgtgat cacccgctat
    14641 gacatcatga acaatatgct gcttgtttcc gtatgcaccg accagcttca tgaaaacgag
    14701 attcctccaa gagttttgga agctgtatcg cgtttccacg cggatgaacc ggaattaaaa
    14761 aaggcacaac aatttttaat caatgaaatc ctgctgcaat ttgattctcc tgaaggactc
    14821 ttagcctata tgggaatcct gcgccgtttc tcttgcaaaa aagaagactt gctggacagc
    14881 atctcagcag tcacgtgccg cgatttgctg caattcatca aaaatcttac atatatcgga
    14941 gctcatgtag taaggggatg agagatatgg aaaaggaagc cttttttcaa cagctggatg
    15001 aacgaaccga tatcagatac acagacaagg gaatgaaaat attcagatta caatttcccc
    15061 gcgcccactt aagactgtgc aatgtcaaaa ccggctttgg aagccaggat gtccgcttac
    15121 agtcagaaac cggcggccgg atgctgccat atggcacagc gcacttttta gaacatctcc
    15181 tcttttggca taacggccgg aacctgtata ctgatttttt tgaacacggc gcgctgttga
    15241 atgcgttcac cacttacact gatacaaatt tcatgtttac ctcattgccg gatcggctca
    15301 gacaaaccat tccaatcctg cttgacgctt tatggaacca ctcgtttgac gagcagatca
    15361 ttgctcagga aaaagccgtg attacaagtg aaatagatac ggcgcttctc aaccaccagc
    15421 ttcattacca ttatcagctg atccagatgc tgtctcctgc ctcaccagcc gcaatattcc
    15481 ccgcaggcag aaaaagagac attgaggctc tgtcgatctg tgatctgcag gaagcctatg
    15541 ctgccgccta ccagccccat cggatgacgc tgtttctgat tggcggccca gaagatgcgg
    15601 aaactctttt gccttctcag ctcagactgg aaaagtgctc tggcagccgc tctgacagaa
    15661 agatcgtccc tgcgtgccct cccctctcat caaaagaggt aaagggtgat ctggagcggc
    15721 cggaagacac ttggaccgga atacaaatcg gggcgctccc aggagaaaac ggacttttga
    15781 ccttgaagct gtattgggac attgcctctc gcatcctgtt tcacatggat tcgccgtttt
    15841 ttcaagagat ccggcaaacg taccgcttga atatccaaag cctgtcagcg gatgttcact
    15901 tatcagagga tggcggcttt ttgatccttc acagtaaagg ggcgcattct tccgcatata
    15961 tcgatgtggc atcttactat atcacgcagc agaaaaaccg taccgaagcc tggcttgagt
    16021 acggcaagga ttctttagtc aacgcgatca tctatgacag tgattacgcg cgtaaatgct
    16081 ttgaatgggc ggcagaatgt gaacagtacg attgctcgtt tctcggcctt taccgcacca
    16141 ttcagcagat gaattctcat gatttcttgg ctctcattga agcaatggtt tcttctaaca
    16201 aagcagtcat tcatgtaccc cagaaagaag tgatgagaca atgaaaaaaa gcactgtctt
    16261 tactttatta ttgctgcttg cggccatggc ggcttattcc ttcggctggt ttcactcagg
    16321 tgccgaagcc gcgggccaat atgtacagct gatcaataat gacgctgccc gccttgggct
    16381 gttggcttgt gccgcttccg tactgatgct tcccgccttt ctctatcttc actacgtgac
    16441 gcaatctgtc aaaaacatga cagcagcttt tcagaaactc acacagtctc atcaaagctg
    16501 ctgtgacttt cagcatcgca agctgtgcag ccgttatgcc gacgatgtaa aattgctgcg
    16561 cgacagctat aggggcatcc gccaatcata tgtgatggct gctgtattgt atcaggtcat
    16621 cgttttcggc tgcatgttcg aaatcgtcaa ggccgttccc ttcagctttc atacgtcccc
    16681 tgccgttaca atggggcttg cggtgttact gattttgtat ttattgtttt atttgcgaac
    16741 gtacttgctg cagctttttc agcatggaaa cctgttccgg aaagtgcttg tgggagtgct
    16801 gacaggagcc gggatttggt ggatgctcag ttttactata agtgaactgc tgtttctgat
    16861 catcttagct gccatccagc agatcggatc ttttatttat aaacgattct cttatcgcag
    16921 ccctgcttct ctcgatctat aaaaacatct acattgcaat cgaggacgga ccggcgccaa
    16981 ccggaatgac cgtcacggct gaatcatcac tcgtgcggta cacggtcact gcattgtcgc
    17041 cgggctttgt cggatgttac tgtgaggtta tagacattag gaagagacac gtttgcaatt
    17101 tcctttgtgg ggcagtatta acgacatata cattgttaat gagaaacggt tcactataag
    17161 actctggaaa ataagcccta gtactatcca gagaacatac aattgtcctc aaagtttcaa
    17221 ataggcggtc aaagccaccc cctgctcaag ggtgacaaac tgatctctgt tacacccttc
    17281 ggtcctagtt caccattcat cacgtctgta ctccatgtaa ccgcagtgac tgcctccgca
    17341 ggatcaacga caaacccctc aggcacttca atcggcactt gaaatggcgc ttcacggctg
    17401 gcatcttcat cacaaaaaca gaaagatcat tctttttcat gatttctcat cccttttaga
    17461 aatgcacaat atccagttga ttaaatcgca atgtcactcg gtgaaacgcc aagcgatatg
    17521 acagtttcca cagaataatc atccgtgttg taaacagtga tgctttgctc tataaaattt
    17581 gttgcataca gaaactcgcc attcggggta aacgcaatgt ctcttgccaa ttgcggaaga
    17641 tttcctatta cgcctgcacc acttggactg acggaatata gattgtgagt gaaatcatca
    17701 aacaaataca cccctgatcc gctcttgaac attccatatt caccttcata ctccagctct
    17761 tgggtgctgc tgatcgtaaa tgtattcaaa tcaatcaccg tcaaataatt gaaaaagaat
    17821 tcttgttcta atacataaag gtaacgttcc ggccaacccg tttctagggc atttacgata
    17881 agatcccgtt caatagtccc tgtcacttca cctgtgttta agtccaatct ttgcactgaa
    17941 ccgaaaccaa gcagatacgc aaacaatcca tttggatcaa ttgcaacatc aaagccttca
    18001 aaaggaatag acctttcaac agttaaggtt tcaattccta tcacatttat ggcaccacca
    18061 gcgacaacat aaaaaaattc gtgtccaggt ataaaagata tggattccgg cggctgatcc
    18121 agcaaaatag aagctgtaac actcaatgtg tcttgactga tgacagaaat gacacgatca
    18181 tagtaatgca aaacaaacac agaggtgtta tctggcgcct tttctatcct tgtaggttgg
    18241 tatggaagag aaatcgtcgt cacaacagta tgagtgttgg tatcaatcac agaaaccgac
    18301 tgatcatctg gattcgctgt gaacgcataa acgggttcgg gctccggcgc aggtacaagc
    18361 acaatcgttc ccgtcaccga taatggactg ccgtaaaatg gcgggacgac aacaaggttc
    18421 tcgatcgtaa tgtcactgac atccggacaa tcatccggtt catcagaata atagacaact
    18481 tgatcgatct ccacattgtg aatgacagaa acagccccct ccccttgtcc atattggttt
    18541 cgcacaggtg agacactgac aagaagcgta acggttccct gcaggcggac tgcaaattga
    18601 acaccgattt catcaggctc aggccccgtt tgaattaagc aacgttcact gacacaagaa
    18661 aggctgtctg cattccacgt gacgtttgca acagcttcag ccggatcaac gacaaacccc
    18721 tcaggcaatt caatcggcgc ttgaaacatc gcttcacgac tggtttcttc ctcacaaaaa
    18781 cataaacaat cttgtgcagc ttctgctttt tctttaaagg aaagcttgtt tttcctcatt
    18841 tcatcacttc cttttcagac atacactgct cacgcagata caacagaata tggaaggtga
    18901 atgtatttgc ttgtacaaac agccgagggt aaaagctgtt tttgaagaaa ttccggccat
    18961 catgcggtgt aacgaaagaa aagattgcgg tttttttgcg cttctcacaa gaatgatgat
    19021 gataaaatat gacatatata gaataatgaa gggagggatt ttcaaacgtg acaagtgtca
    19081 tatcttcttc ttccgttgga gaaaagatta atgaatggta tatgtacata cgccgattca
    19141 gcataccgga tgcggaatat ttacgaagag aaatcaaaca agagctggat caaatggaag
    19201 aagaccagga tcttcatttg tattattcac tgatggaatt ccggcacaat ctgatgcttg
    19261 agtatcttga accgttagaa aacatgcgga tagaggaaca gccgcgactg tccgatttgc
    19321 tgcttgaaat cgataaaaaa caggctcgtt taaccggagt ccttgactat tactttaatt
    19381 tcttcagggg catgtacgaa ctggaccaac gggagtactt atctgctatt aaatttttca
    19441 aaaaagccga aagcaagctg attttcgtaa aggatcgaat agaaaaagct gaatttttct
    19501 ttaaaatgtc tgaatcttat tactatatga aacaaacgta tttttctatg gactatgcac
    19561 ggcaggcata tgaaatatac aaagagcaca cagcatataa tattagattg cttcaatgcc
    19621 attctttgtt tgctaccaat ttcttagacc tcaagcaata tgaggacgcc atatcacatt
    19681 tcaaaaaagc ttatacaatg gcagaatccg aaaaacagcc ccaattaatg ggaagaacgc
    19741 tgtataacat cggactttgc aaaaacagcc aagaacagta tgagtcagca atcacatatt
    19801 tcaaaagagc catatctgtt tttgaagaag ctaacattct tccttctctg cctcaagctt
    19861 attttttgat tacacaaatt cattataaat taggaaaaat ggataaagct catgaatatc
    19921 atagtaaagg aattgattat tctaaagagg ctggagacat catttactta tcagagtttg
    19981 aatttttgaa atctttatac ttatcaggtc cggatgaaga ggcaattcag aaattcttcg
    20041 attttctcga aagtaaaatg atgtatgctg atcttgaaga ttttgcgctt gatgtggcaa
    20101 aatattatca tggacgtgaa aatttccaaa aagcttccgc gtattttcta aaggtggaac
    20161 aagtaaggca acttattcaa ggaggagtga gattgtatga aattgaagtc taaactatta
    20221 ctctcttgtc tggccctaag cactgtgttt gtcgcaacga atattgcaaa tgcacctaca
    20281 caccaaatgg aagttgcaca gcgaggaatg atttaagata aaccgccttt atcggcggtt
    20341 tttttcgtcc cctctttcca ccttgaagaa gatgtttgca aagcatggga acaaaaaaca
    20401 tccagacaaa gtctggatgt ttctcttatt tcacaaaccc aagcagcatt tcacgaatga
    20461 ttttgctggc tgtgtttgcc gtttgctctg agtggtcgta aatcggagct acttctacta
    20521 aatctgcgcc cttcacgttt acttctgagc gcgcgatttc atgcacggat gcaagcagtt
    20581 ctttagacgt gatgccgcct gcgtcaaccg ttcctgtccc cggtgcgtgg gcagggtcta
    20641 atacgtcaat gtcgattgtg acatataccg gacggcctgc cagcttcgga agaacctctt
    20701 tcagcggctc aagcacttca aacttagaga tgtgcatgcc gttttccttt gcccattcga
    20761 actcttcttt cataccggaa cggattccga atgaatacac attttccggg ccgattaatt
    20821 ccgccgcttt acggatcggc gttgagtgag aaagcggttc tccctcatag tcgacgcgaa
    20881 gatccgtatg tgcatcaaaa tgaataatcg ccaggtcagg aaatttcttg tacattgctt
    20941 tcatgacagg ccatgacacg agatgctccc cgcccatacc catcgggaat tttccttttt
    21001 ctaaaatact gtccacatat tcttcaatca tatcaagact tttttgcggg ttgccgaatg
    21061 gcagcggaat gtcgccggcg tcaaagaagt tcaggtccgc cagatcaagg tccagatacg
    21121 ggctgtattc ttcaaggccg attgacacct cgcggattct tccagggccg aagcgtgatc
    21181 ccggacgata gctcaccgtc cagtccatcg gcatgccgta aaggatggcg tccgcctctt
    21241 cccactctgg acggctcgcg ataaatactt ttcctgaata agcttcatca aatctcatct
    21301 ataaaaccct cgctttcctt taaaaaagcg caagattcgc tcctgcgcca tacattcatt
    21361 atttaatcag gtcactcaca aatttcggca gaacaaacgc cgctttatga atatcttttg
    21421 tgtaatattt cgtatcaata tcaaagaaac ggctgtcttc cactgcaagc ggatcatatg
    21481 ttttcgaacc gattgtaaat gtccacaaac cgcttgggta tgtcggaatg ttcgccgtat
    21541 acagcttcgt aatcgggaag atttccttca cgtcacgctg tacatttgtg attaattccg
    21601 gtgtgaacca tg
//
