LOCUS       NZ_AP018365            31751 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Streptomyces sp. SN-593 chromosome.
ACCESSION   NZ_AP018365
VERSION     NZ_AP018365.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. SN-593
  ORGANISM  Streptomyces sp. SN-593
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Panthee,S., Kito,N., Hayashi,T., Shimizu,T., Ishikawa,J.,
            Hamamoto,H., Osada,H. and Takahashi,S.
  TITLE     beta-carboline chemical signals induce reveromycin production
            through a LuxR family regulator in Streptomyces sp. SN-593
  JOURNAL   Sci Rep 10 (1), 10230 (2020)
   PUBMED   32576869
  REMARK    DOI:10.1038/s41598-020-66974-y Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Takahashi,S., Toyoda,A., Sekiyama,Y., Takagi,H., Nogawa,T.,
            Uramoto,M., Suzuki,R., Koshino,H., Kumano,T., Panthee,S., Dairi,T.,
            Ishikawa,J., Ikeda,H., Sakaki,Y. and Osada,H.
  TITLE     Reveromycin A biosynthesis uses RevG and RevJ for stereospecific
            spiroacetal formation
  JOURNAL   Nat Chem Biol 7 (7), 461-468 (2011)
   PUBMED   21642985
  REMARK    Publication Status: Online-Only
REFERENCE   3
  AUTHORS   Panthee,S., Takahashi,S., Takagi,H., Nogawa,T., Oowada,E.,
            Uramoto,M. and Osada,H.
  TITLE     Furaquinocins I and J: novel polyketide isoprenoid hybrid compounds
            from Streptomyces reveromyceticus SN-593
  JOURNAL   J. Antibiot. 64, 509-513 (2011)
REFERENCE   4
  AUTHORS   Takahashi,S., Takagi,H., Toyoda,A., Uramoto,M., Nogawa,T., Ueki,M.,
            Sakaki,Y. and Osada,H.
  TITLE     Biochemical characterization of a novel indole prenyltransferase
            from Streptomyces sp. SN-593
  JOURNAL   J Bacteriol 192 (11), 2839-2851 (2010)
   PUBMED   20348259
REFERENCE   5  (bases 1 to 8833490)
  AUTHORS   Takahashi,S., Ueki,M., Toyoda,A., Ishikawa,J., Sakaki,Y. and
            Osada,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2017) Contact:Shunji Takahashi Chemical Biology
            Research Group, RIKEN Center for Sustainable Resource Science
            (CSRS); Hirosawa 2-1, Wako, Saitama 351-0198, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Phrap v. 0.990329
            Genome Coverage                   :: 16x
            Sequencing Technology             :: ABI 3730
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016756395.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 03:58:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,420
            CDSs (total)                      :: 7,334
            Genes (coding)                    :: 7,181
            CDSs (with protein)               :: 7,181
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 153
            CDSs (without protein)            :: 153
            Pseudo Genes (ambiguous residues) :: 0 of 153
            Pseudo Genes (frameshifted)       :: 35 of 153
            Pseudo Genes (incomplete)         :: 136 of 153
            Pseudo Genes (internal stop)      :: 8 of 153
            Pseudo Genes (multiple problems)  :: 25 of 153
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:29:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7986832
            Orig. end                         :: 8018583
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP018365.1.
            This work was done in collaboration with Shunji Takahashi, Masashi
            Ueki, Atsushi Toyoda, Yoshiyuki Sakaki and Hiroyuki Osada (RIKEN)
            and Jun Ishikawa (National Institute of Infectious Diseases).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31751
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iv"
                     /region_number="30"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..31751
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..23120
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23120
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13120](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13120)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    180..194
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 15.47"
                     /tool="antismash"
     gene            624..1805
                     /locus_tag="RVR_RS33930"
                     /old_locus_tag="RVR_9488"
     CDS             624..1805
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019988.4"
                     /locus_tag="RVR_RS33930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9488"
                     /product="PhlD"
                     /protein_id="WP_202237745.1"
                     /sec_met_domain="fabH (E-value: 4.2e-17, bitscore: 61.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIAVGKPVVVRAPHEVSTDAIEADWLARWPPETRLPEQRRRLAG
                     ALRMVRSTTVANRPWVAPLEVVGDGARDAREVYEAAFAAVVDMAAEAAHGALAAAGLAP
                     EDVDCVVTTHTTSWTIPQLDVALVNRLGLRRDVARVPAATLACAGGAHALVQATRYLAG
                     RPEGVVLVVAGEALSILHMPWREPTRTGVLYGALFGDSAGAAVVAGAGRRQEDSARRLV
                     AAGGGLVADVETWEWLQHGESPYWGELHPGGVPGAGRITFESNRDATKGARETMPHLVK
                     WLNGRQVDWAVVHPGGPGIIADTVDALGLPPEAGRHSADSLRGGNLGGVAVLDVLRRTL
                     DEGPARGPGLLVAYGPGFTADALFLDVPEADVPEADVPGADVTGTTVPGAATP"
     gene            complement(2041..2655)
                     /locus_tag="RVR_RS33935"
                     /old_locus_tag="RVR_9489"
     CDS             complement(2041..2655)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557498.1"
                     /locus_tag="RVR_RS33935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9489"
                     /product="hypothetical protein"
                     /protein_id="WP_202237746.1"
                     /transl_table=11
                     /translation="MAVHEHPRQRTGFRLPTRRSAVAVHAGDTAAGAGAARRSLAAVRI
                     ATGLVFLWAFLDKLFGWHYATASGRGWVDGGSPTKGFLSGVSAGPLQSFFHHIAGQGWT
                     DWLFMLALLGIGAALTGGVALRMTAVAGTVLMALMWAAEWPPAQHLSTGAPSGSSNPFV
                     DYHVVYALVMVLSAYAAAGTTWGLGRVWAALPIVRRHRWLL"
     gene            complement(2711..3568)
                     /locus_tag="RVR_RS33940"
                     /old_locus_tag="RVR_9490"
     CDS             complement(2711..3568)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012791.4"
                     /locus_tag="RVR_RS33940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9490"
                     /product="universal stress protein"
                     /protein_id="WP_202237747.1"
                     /transl_table=11
                     /translation="MSPPRVLVGIDGSVTSFLALETAAAEARLRGARLELLACAADPAE
                     AGPVLRAAVAHAARLRPGLTVTASSATGDPADVLVRLGRHAQLTVVGARAVGGGAGLLA
                     HSVARRVAARAAAPLVVVRGMQPRPRVRDRRTGRVLLAVEDDADADAALFAFQEAELRG
                     TTVAVLHPWTYRRRTGTGTAAPRCLPRGELAKATEGAGLIVVGARRHARWTSPPPGPVA
                     DLLLRHARCPVAVVPPPRNGTGPDDGPGRRRGPGRDSAPGPTDLAGRAVRPPRRGPGPP
                     AARS"
     misc_feature    complement(3706..3720)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     misc_feature    3707..3721
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 27.49"
                     /tool="antismash"
     misc_feature    complement(3919..3931)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.17"
                     /tool="antismash"
     gene            3976..6360
                     /locus_tag="RVR_RS33945"
                     /old_locus_tag="RVR_9492"
     CDS             3976..6360
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010263946.1"
                     /locus_tag="RVR_RS33945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9492"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_202237750.1"
                     /transl_table=11
                     /translation="MARRQEPLFTVDGIGRVTSWSAAAARRFAHGEEAALGRPADALIR
                     SAALGPDPAGGDPGLLAVPLEEDGAWALYAQPRGPQGLDAAIEDALLRALLSESQLSIV
                     VLDTDLRLVRVSMATQALRRPGADIMGKRVDEAYPLDRPQEELAVLERVLSTGEPVYSR
                     LVGTAVAGRTGRRFFSASAFRLSRPAGEVIGVAVTLLDVTRRERDHVRRQAVSRVRQEV
                     GRSLGLARTCEDLAGALVPEFADIVLVALAEQVTAGDNPPSMPADPAALLLRTVAVQGR
                     ADGADGRKTGGADHAEDGGRGGDGADGADAGDAPGIEWIEAVGDIGDIGDVEAVERESS
                     FAQAVTEGRPVLRTTRRAAHLLDLPAHDEILRAAGAHSMVVIPLAVRGRLLGLAVAVRT
                     GDSARYLRADLAAAEEIGLHTALCLENARRSAVARVIASTVQRRFLPERPRSALGVETA
                     FVALSPPSRKGAWFDVIPLSGARCALATGEIGRGGTASLTAMGRLRTTLRALADLELQP
                     DEVLARLSDTVAGIPSDAALPEETGALSVACTYGVYDPATSVFTVSCAGQPAPRVIAPD
                     GGVVRLGEAVGPRLGGEGMEPFGMVTHSVPHGATLLLASADFDEVLDSGGELRQALRTS
                     GSVQDLANALFVKLAPQPGRSGTAMLARTNRLGTDRTIAWELPAADEAASKARRLTRQW
                     LRDRSATVTAETVESAELLVSELVTNAVRYGAPPITLRLTLNDALTVEVRDHRTATPSI
                     RHARVTDEGGRGLLIVSHLSGKWGTRRVEEGKAVWAEQSMT"
     gene            complement(6676..9675)
                     /locus_tag="RVR_RS33950"
                     /old_locus_tag="RVR_9495"
     CDS             complement(6676..9675)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488912.1"
                     /locus_tag="RVR_RS33950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9495"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_237405134.1"
                     /transl_table=11
                     /translation="MLITSPMVIGRGAELAVLDEGLAAARDGDGRAVFLLGEAGIGKSR
                     LAAECAFRAFTRGLAVLRGRSGATGGAAATPFRPIAEALLSFVRLGGLPEPEELAPYRS
                     ALGGLLPEWRAAGHAGVPASPVETAEAMLRLLVTIGRDLTQHRQPGCLLVLEDLHDADT
                     ETLALIEYLCDNLRGQPIFLLATLRPEPGPAEQLARQAAQRRSAILSEPRPLGGEEVRA
                     MAEAALAATGSPPHDTAAVLPQEVVDRLTRDADGNPFVVEELLSGMITADVLRRGPGGA
                     WHVCGDLDIDVPRTVVHSVSQRSARLSPDGRALLDSAAVLGRRFSLAVLQAVSGLPDRD
                     LLVHLRAGMDAHLISPSRPVGDWYEFRHALTAEALVAALVPAERAAIAARGADAIERAH
                     PGLPGEWCVLVASLRETAGDARAAALRFAEAGRSAQAGGAVNSAVSLLERALDLLPGPD
                     RAAERAPLVEQLVFTLAENGQLDRACALADELPDAGPGALDAVRAATLQARIAWAAVTA
                     ARFEDAAERVRRVRQLLRLVPDGDGPAAGAALGPAVKMVEAHLILSGVREHAGDRTHEA
                     ERLARQAADGAERAGLPEIGCQAWQLLAVLARRHGFEQSDSYLEKCLVLANEHRLTAWQ
                     LDTLMWLGVNDFMCTGSSARLERAHRAALGHGALALMYRAEATMAMQQVLRGDYTGARE
                     LADRCAEGTARLRDADNHQFVLLTRVALAAHQGRRRQMEQELAEFRRWGGEQSLQSPQA
                     FGSRAICALLEEDHDRALRELDEAFAWEQGNPSVHYLNGRYGLRPLLRALTGQADPDEH
                     AAIAADPNAALPWNRQFERLAFAVHEGRAGRGARAEAAVAQAREAGEPFLMARRLGQRL
                     VAPVALADGWGDPVGWLRDAEEYFHGAGVPAVANSCRDLLRRAGATVRQRRHGTPGVPA
                     PLRSQGLTAREYEVFVLLAPRLGNQEIAERLYISPRTVEKHVANLIAKTGSPHRSALCD
                     YATDLLAQLD"
     cand_cluster    9046..31751
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    9046..31751
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[19045:21751](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      19046..21751
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="2"
     misc_feature    complement(9650..9664)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            complement(9733..9951)
                     /locus_tag="RVR_RS33955"
                     /old_locus_tag="RVR_9496"
     CDS             complement(9733..9951)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS33955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RVR_9496"
                     /product="hypothetical protein"
                     /protein_id="WP_202237751.1"
                     /transl_table=11
                     /translation="MSDNPLVNAWKNPTARAGAAAAHPAGSIRLGTGAVVGRRAQLLAG
                     LASTGEDPDHFPTYSLTLTSWGDTGGY"
     gene            complement(10001..13120)
                     /locus_tag="RVR_RS33960"
                     /old_locus_tag="RVR_9497"
     CDS             complement(10001..13120)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="RVR_RS33960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9497"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_202237752.1"
                     /sec_met_domain="DUF4135 (E-value: 3.1e-97, bitscore:
                     324.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9.4e-25, bitscore:
                     85.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDPQTWWVGGVALAERLPPPPEPVNATSLTESWQSDYSSPALLR
                     ARLADTGLDEGGLRALLAEEPAALAGRIGRPGWATTVEQALARAPLDPPPPAGDSWSEG
                     FAAVLAPFTDTADERLLRAVEGLGPDRPGGADRTDRTDGPARPAGLADLAGLADIADLA
                     AVRGCFADQLSRALVRIARRTLVLELNVLRVRGRLCGSTPEQRFRDFVRQTSARPGLHA
                     LVTEYPVLARLLAQCCDQAVETWEELLRRFAGDRSALVAGPLAGTDPGRLVAVDMGAGD
                     RHQGGRAVAVLSFEHGGRVVFKPRPVAVHAHFNDTVRWFNSRLPGLGLRRLAVLERPGY
                     GWIEYAATAPCTGPAEVGRFYWRLGALLALVHALGATDMHFENLIACADQPVLVDLETL
                     FHPDLHLPGGGDPAQAVLTASVARTALLPFFLVGEHGVLDVSGLGGDRDTPLPEEVTGW
                     SAPGTDEMHLIRTVGTFRGSANRPLLRDAEADPAAHVDLLVAGFRAGYDAIAGHRAELT
                     GPGGLLSRFTRDVTRAVLRPTRWYANLLDESTHPDVLREALDRERLFDVLWRDAADGPG
                     ARALASAELAELWAGDVPVAACSPGTAGLMVGPLTADGLVAEGGLARAERRIAAMGETD
                     RFDQEWVIRATLATRRRHDAPRAAVPPHGVPAATVPDAERLLAAACGIADRILARAQDD
                     GRRVNWLCLEPLDDRIWAVQPQGAGLPHGYCGTALFLAQLAALTGTERYTSVARRALTP
                     LPDLLTALAGRPADLPAVGAGFAGLGGIAYALGRLATLLDDAEIAGWTAAAVDLAAAAA
                     GDDPQPSVLDGDAGCLAAMLAVQRATGSAAAGRAARACADRLAARAPDELPAGGFGTGA
                     AGVGWALLRFAAAGGGRDHAAAGLAALRTAAARCAAQPVGTGWCDGPSGTALAVADSAL
                     AADVPELAKLLDVVVERSAAPTAGDHCLCHGEAGALDLLLAATGAGRAEPGTALPRAAA
                     LLAALDRFGPRCGTPDAVSSPGLLTGLAGIGHELLQLGFASRVPSVLLLR"
     misc_feature    13612..13627
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.49"
                     /tool="antismash"
     gene            13617..15068
                     /locus_tag="RVR_RS33965"
                     /old_locus_tag="RVR_9500"
     CDS             13617..15068
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="RVR_RS33965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9500"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_202237754.1"
                     /transl_table=11
                     /translation="MSDDHQAVERPAQGPGTAQAPAAGRESASGAAGGTSWSGAAPRAR
                     RSADPDGRVLVLRSPAARAAGRRLARQRPHRTVLAFQRSYRSAVPAARERARMEEVLLG
                     GRHPAQDGDAARLGAAVAEATAVAAVIEAPRRQLLLAVDAVFRGRFAEASALVETAWED
                     IDRLRLHGLGSHALAVKALIHAHQGERDALAEASTRFDAWRGDREDEVPIVEGLGHAVC
                     ELLHGAGDAARARLRHLHPGDDGRAGGGEPSGTLQLCGPYGLTLLLDCLDGTAGRDDHA
                     AIAAHPAARLPWNAHFVHLAEAVVAGREGDASAAEAALRQALAAAAGYPPARHLGLGLV
                     ARAAARDGWGEPVRWLQEAELFYAAHGIDPAVRHCRSLLRELGERVRQRRHGSGDVPDR
                     LWHLGVTVREFEVLVLLDRRHTNREIAAELHLSHRTVERHVANLLEKTQAGNRRELAAL
                     LAPEPRESREPREPGGFREPVGVGG"
     gene            complement(15326..15583)
                     /locus_tag="RVR_RS33970"
                     /old_locus_tag="RVR_10546"
     CDS             complement(15326..15583)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS33970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RVR_10546"
                     /product="hypothetical protein"
                     /protein_id="WP_202237756.1"
                     /transl_table=11
                     /translation="MLTFPLEDVVRSVLAALDERDWKVEDDGVWCRVTPPRHTSRVQGW
                     KLHVSTTRLSAPEVPHRAAGVWSAPGAPSRRPVTWGPSSR"
     CDS             complement(15821..16045)
                     /gene="allorf_8002653_8002877"
                     /locus_tag="allorf_8002653_8002877"
                     /protein_id="allorf_8002653_8002877"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRRHETLLPRRGHAARAVRAVGPLPRRRGARRVPGAPRRDRTGAT
                     GSTGATRATRAPCATGTDDVSGPRPGHGC"
     CDS_motif       complement(15938..16045)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRRHETLLPRRGHAARAVRAVGPLPRRRGARRVPGA"
                     /locus_tag="allorf_8002653_8002877_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15821..15937)
                     /prepeptide="core"
                     /locus_tag="allorf_8002653_8002877_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.70"
                     /molecular_weight="3605.9"
                     /monoisotopic_mass="3603.8"
                     /core_sequence="PRRDRTGATGSTGATRATRAPCATGTDDVSGPRPGHGC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRRHETLLPRRGHAARAVRAVGPLPRRRGARRVPGA"
                     /leader_location="[15937:16045](-)"
                     /alternative_weights="3623.9"
                     /alternative_weights="3641.9"
                     /alternative_weights="3659.9"
                     /alternative_weights="3677.9"
                     /alternative_weights="3696.0"
                     /alternative_weights="3714.0"
                     /alternative_weights="3732.0"
     gene            16183..18771
                     /locus_tag="RVR_RS33975"
                     /old_locus_tag="RVR_9505"
     CDS             16183..18771
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS33975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RVR_9505"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_202237757.1"
                     /sec_met_domain="LANC_like (E-value: 0.00061, bitscore:
                     17.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDVFTFADPDFYVPPSAVADRGPHLRPAAAPDGWTAVRTGWWT
                     GWTPASGPRFGDGDLRVYASAGPEPLQPVLDAFAAACFARGVPFRHVANQSVHHHLNHP
                     RGSRAQAGRFCVAAPADAAAAEDLVRALHAAAVFAASAAPAAEAHQQAAPTVRHGRVPA
                     PSASAVRPDGTRSTEDYLMNAPAPTPVAPAGFEVRGLRAASTDGYSFTARNVMDGSEVF
                     VKQALPQAAPAGDGRSAADRLRAEWRVLARVHHEAPGLCPRPLVFVEGRPYPYLLAELV
                     AGVPLTSWVVANSPVADPAASAGDWSRYHRRAADLIARIERDLRRLWLLGYPVDGVEAR
                     DVLVDRDDGIRLTGGLTRGTASGADTDGAARRGGADGPSRTAARLGLLLLTPLAPVAER
                     NPGVLPHILRDLTERAPVPPRLWHAATRPADSRAGAGVPLPSPEQVDADERGALTELRD
                     RVAAGILDAAADRPWGVFPSVPQGYETNTLGVAYGTAGVVHALRTAGVDIPAWITRRLR
                     EDALRQAGSLPPGLYSGLAGIAWVLADLGFQDEARDLLGAADRHPLTRDSATLAWGASG
                     VAMAHLALYGHSRDASHLDRAVELTRLPQRSAALSARLGPHDMTGLFYGRAGVAHALQQ
                     VGAVTGEDRLRRGALRLLHAELDRARQSAGGELVFPVSAKDRRGMYYLHCGTAGFLTAA
                     SRALAAAPDERLALAVPRLVAKSSITYVAHAGLFQGLAGLGFALAECGRLLDDERARAA
                     SWRSARTLFAHALPSGGAVRFLGDLRLRQSCELWSGASGVLLFLSHLLDQRPDPLFSVD
                     SLARDAAAARGRAPARREPLARRGTAARRAAPAPARTPQMSARQPAARKP"
     CDS             18799..18912
                     /gene="allorf_8005631_8005744"
                     /locus_tag="allorf_8005631_8005744"
                     /protein_id="allorf_8005631_8005744"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSQVLNLQEMEIPAPEQEQEVEGSYFICSDASWFLCA"
     CDS_motif       18799..18870
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSQVLNLQEMEIPAPEQEQEVEGS"
                     /locus_tag="allorf_8005631_8005744_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       18871..18912
                     /prepeptide="core"
                     /locus_tag="allorf_8005631_8005744_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.50"
                     /molecular_weight="1489.7"
                     /monoisotopic_mass="1488.6"
                     /core_sequence="YFICSDASWFLCA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSQVLNLQEMEIPAPEQEQEVEGS"
                     /leader_location="[18798:18870](+)"
     misc_feature    complement(18874..18887)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.63"
                     /tool="antismash"
     CDS             complement(18875..18994)
                     /gene="allorf_8005707_8005826"
                     /locus_tag="allorf_8005707_8005826"
                     /protein_id="allorf_8005707_8005826"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRPRAGGEVGPRAGGATRGTDASPRRCLRRRGTSWRRCR"
     CDS_motif       complement(18950..18994)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRPRAGGEVGPRAGG"
                     /locus_tag="allorf_8005707_8005826_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18875..18949)
                     /prepeptide="core"
                     /locus_tag="allorf_8005707_8005826_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="2785.2"
                     /monoisotopic_mass="2783.5"
                     /core_sequence="ATRGTDASPRRCLRRRGTSWRRCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRPRAGGEVGPRAGG"
                     /leader_location="[18949:18994](-)"
                     /alternative_weights="2803.2"
                     /alternative_weights="2821.2"
                     /alternative_weights="2839.2"
     gene            19046..21751
                     /locus_tag="RVR_RS33980"
                     /old_locus_tag="RVR_9508"
     CDS             19046..21751
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="RVR_RS33980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9508"
                     /product="protein kinase/lanthionine synthetase C family
                     protein"
                     /protein_id="WP_202237758.1"
                     /sec_met_domain="Pkinase (E-value: 4.7e-09, bitscore: 34.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.3e-11, bitscore:
                     40.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEQTYAMADADYYAPVETLKDRGREYAPAKVPDGWRSFDRYLWR
                     SWGRAGLPMPDQGWKVHVSARAERIADVLDTVAEECFARDVPFKHVAAERFVLLLQHKH
                     ASRTQSGKLVVAYPADERAAAALMSALAARLESEQGQFILTDRRFGDSRVVHYRYGSFT
                     PRRRLLPDGTGTPVLRDGRARLVADRREPRFHLPEGITDPFAAGGAQAPAETSGTAKAA
                     GTAEAAGPVESAGTAEAKGPIEAAGTAEAEGPTEAANTAEPSFHGFAFDHAVRHSNGGG
                     AYAGRELATGRKVFIKEARDHTGLSWDGLTAVERTRREWDTLRALHAAHPGICPEPIAY
                     FREWEHEFLVTEFVPGTTLNTWVAARSPVTRVEAEPPEAERYTADCEAIAASLEEQVRV
                     LHGLGYLFGDVSPGNVLVGDDGRPRLVDFEAARSLGDKGVSVATDGYAPPARLVRDDPT
                     VPDHYGISALVRLMLGPTFAVADRYPRSLEHLRADLQERMAVPQALWGRAVRFHPADGP
                     ALLPGPREVAADPVRHVRDLRDEVARALTSMADPDRADTLFPTVPDGYASNTVCVAYGA
                     AGVLHALWHGGVAVDEAVVARFRRDALAAAGSLPPGLHVGLAGVAWVLADHGYLDEARD
                     LLATATEHPLATRRAGFAEGAAGVAMAHLSLFAHTGDHGHVDTAERLLSALPPDGELSG
                     LLDRDDPTGWLHGRCGIAWALHPLAAVTGDARYLERGVRLLHHELDRAMPGGAASPHFP
                     VSATDRRSMPYLFCGTAGTLRAVCRYNTVCQDERLAGVESDLMPRLRTTYTVMPGLYQG
                     LAGLGFALADHASVRGDEVSSRAALRTARALFKYAVPGPTGVRFHGEKLKRFSADLWSG
                     GAGVLLFLDQVLDGGADRLFSLDRLVPAGS"
     CDS             21777..21893
                     /gene="allorf_8008609_8008725"
                     /locus_tag="allorf_8008609_8008725"
                     /protein_id="allorf_8008609_8008725"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRTIVHQSWRSDGLNGRVHPLSIGANLAASRPRCYVPT"
     CDS_motif       21777..21866
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRTIVHQSWRSDGLNGRVHPLSIGANLAAS"
                     /locus_tag="allorf_8008609_8008725_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21867..21893
                     /prepeptide="core"
                     /locus_tag="allorf_8008609_8008725_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="973.1"
                     /monoisotopic_mass="972.5"
                     /core_sequence="RPRCYVPT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRTIVHQSWRSDGLNGRVHPLSIGANLAAS"
                     /leader_location="[21776:21866](+)"
     misc_feature    complement(21888..21904)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 14.65"
                     /tool="antismash"
     misc_feature    21891..21905
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.72"
                     /tool="antismash"
     misc_feature    complement(21894..21907)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 11.39"
                     /tool="antismash"
     misc_feature    21894..21908
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.8"
                     /tool="antismash"
     gene            22065..23723
                     /locus_tag="RVR_RS33985"
                     /old_locus_tag="RVR_9509"
     CDS             22065..23723
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430975.1"
                     /locus_tag="RVR_RS33985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9509"
                     /product="carboxylesterase family protein"
                     /protein_id="WP_202237760.1"
                     /transl_table=11
                     /translation="MNVPPSDTPPSEPSPRHRREAPGRTAGAGPARGTVRIDTGLVSGV
                     PGALPGVTVYRGIPYAASTAGPDRWRPPRPAPSWEGVRAADTFGDAPPQAGTGFAMSED
                     CLNLNVWTAASAGGERRPVYVWIFGGGFSGGRGSDPVFDGSVLAGKGLVVVTFNYRLGA
                     LGFLATPGLSRESAHRASGNYGLLDQIAALEWVRRNISAFGGDPDQVSIGGQSAGAGSA
                     GMLSLSPLAAGLFRRTVAQSHARHPGDPELRYLGTSYRRLDAAERQGAAYAAAHGATTP
                     DELRALPWQDLDDAGTLGDDGVDTRSAARPPLFRPVLDGWVLPAGYHDTYARGAQNDVW
                     YLAGNNLDETGAVPETAFDHWRRTGRRDRPGAPPVHVTLDDFVGSARHTYGALAMEFLR
                     LYPAATDDEAARAANDAVRDRSRATTHLWGTQWVRGCGRPVHTYFWTHRPPGPDHDIRG
                     AGHGSEIPYFFGTLHPADQGWTGRDREIADTMSSYLANYVATGDPNGPGLPAWPAYDPR
                     TPTVMEVGAHFGPIPVAPPAELDFWKRYFAAQQPW"
     gene            24047..>24685
                     /locus_tag="RVR_RS38195"
                     /pseudo=""
     CDS             24047..>24685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514658.1"
                     /locus_tag="RVR_RS38195"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="lamin tail domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRVLPVGAAGALVLAGLVMHSASAAPSPDGVIAEVYGGGGNIGAT
                     YTSDFVELANAGTSTLDLSGYSVQYLRGTPTPTSSWRATALSGTLAGGGRYLVQEWSNT
                     GGAVSLSDPDAVGTINLSATDGTVALVSGTAPLTCLTAADCAADPRVKDLVGYGSAVVH
                     EGAGPAATADNTTSVARGDSLADTDDNAADFTAGAPTPQNSLSAGGGTAG"
     gene            complement(25290..26492)
                     /gene="lhgO"
                     /locus_tag="RVR_RS33995"
                     /old_locus_tag="RVR_9513"
     CDS             complement(25290..26492)
                     /EC_number="1.1.3.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lhgO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014178358.1"
                     /locus_tag="RVR_RS33995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9513"
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="WP_202237762.1"
                     /sec_met_domain="DAO (E-value: 8.2e-63, bitscore: 211.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSHYDVVVIGGGIIGLSTAYAVTRAAPGRSVAVLEKEPALARHQ
                     SGRNSGVIHSGIYYRPGSFKARFALRGAREMVEFCAAHGIAHEVTGKLIVATTAPELPR
                     LADLARRGEQHGIPVRTLGVREIAEHEPHVRGLAAVHVGTTGVADYPAVARRFAELAAR
                     DGAEVHLGCEVLALTRAPDGVMVHTTAGEVRAGVLVNCAGLHSDRVARMAGDEPGVRII
                     PFRGEYYELAERSRGLVRNLVYPVPDPAFPFLGVHLTRDVHGGVHVGPNAVLAAAREGY
                     RWRDFRAREAADIAGWPGLRRVARRHWRREVGELWRSASKTAFTAAVRRMLPDVTRNDL
                     VRAPAGVRAQAVRADGTLVDDFLFTGAGPFVHVLNAPSPAATASLPIGREIAARALRTL
                     E"
     gene            complement(26548..27876)
                     /locus_tag="RVR_RS34000"
                     /old_locus_tag="RVR_9514"
     CDS             complement(26548..27876)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068678.1"
                     /locus_tag="RVR_RS34000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9514"
                     /product="lysine 2,3-aminomutase"
                     /protein_id="WP_202237763.1"
                     /transl_table=11
                     /translation="MTVVQGSSDPAVPGFPAAPVFSAVTAGRLAELVGAAGFTGSQVTA
                     IRAVAEVLPFRTNRYVVEELIDWSAVPDDPIYRLVFPQEDMLPAGDVARIADLLTRGAA
                     PKEVAAAANAVRRRLNPHPAGQLELNVPRHAGAPLPGMQHKYRETVLFFPKQGQTCHSY
                     CTYCFRWAQFVGDADLKMASGDIGQLKRYLADHPEVSNVLFTGGDPMIMRAGVLRRYVE
                     PLLELDQLESLRIGTKALSYWPYKFTTDPDADDMLRLFEEVSRSGKDLSVMAHFSHPRE
                     LRTPVVEQAVRRLRGAGASIRTQAPLMRYINDDPAVWSAMWSRQVSMGMVPYYMFVERD
                     TGPQEYFKVSLADAHDIFRRAYRDVSGLCRTVRGPSMSTTSGKVCVDGVVDVAGEKVFA
                     LHYIQCRDADAVGRPFYAKFDPAAAWFSELVPAFDGGFPAGAA"
     gene            complement(27851..28795)
                     /locus_tag="RVR_RS34005"
                     /old_locus_tag="RVR_9515"
     CDS             complement(27851..28795)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="RVR_RS34005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9515"
                     /product="DMT family transporter"
                     /protein_id="WP_202237765.1"
                     /transl_table=11
                     /translation="MKRTLPPDLQGFLYGFLGVLGFSLTLPVTRVGTESLPPELVGPGR
                     SLLAVIPAGALLLARQRPLLPPRHHVRGVVVTSLGTVIGFPLLTAHALRSVSASHAAVV
                     VALLPATTAVMAVLRGRERPSATFWVCCALGTALVCGYVLLGFGGGLHVGDAELLAAVV
                     ACSLGYAEGGVLARDVPGWVVTSWALVAGTPPAALAVALAWPSPGPSLDARGAAAFVYL
                     ALGSSLLSFFCWYRGLSAGGVAKVSQVQLLQPVLTMLFAAVLLDEPLRPSAVLVGLAVG
                     VVVLATLRTRTGGSSGPATIREGTVHDRRPGLE"
     gene            complement(28830..29978)
                     /gene="metK"
                     /locus_tag="RVR_RS34010"
                     /old_locus_tag="RVR_9516"
     CDS             complement(28830..29978)
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514449.1"
                     /locus_tag="RVR_RS34010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9516"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_202237767.1"
                     /transl_table=11
                     /translation="MPSPSSGPPWSQIAESVTPGHPDKVADQISDAVLDAYLAADPYAR
                     VNCEVMVTRDHVLVTGQVTAAGAVDVEAVARGVLSDVGYRDVAVHGIDAARSPVTVVLD
                     HQSREIGSGVDEGGSGDSGVVYGYACDETPELLPLSCVLAHGLTRALAEERLRSPDSGL
                     GPDGKVQVEVAGGDRSPRGRVVLSVQHAAGRPLDAVREFCAEQVVGPVLAARDLPVEWA
                     EVNPAGSFVVGGTAADAGLTGRKLMVDTYGGLARHGGGCFSGKDATKVDRSGAYVARQL
                     ALTAVAAGLAARCQVGMAYAIGRPEPVWFEVDCSGTERVDPAKLTSALRSLTDLRVDAT
                     ISRLRLRHTSFRPTATFGHFGRTGGLPWEQPVRADELRAQTS"
     misc_feature    29987..29999
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.34"
                     /tool="antismash"
     gene            complement(30030..31094)
                     /locus_tag="RVR_RS34015"
                     /old_locus_tag="RVR_9518"
     CDS             complement(30030..31094)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (26-346). E-value: 3e-44.
                     Score: 143.5. Matches aSDomain:
                     nrpspksdomains_RVR_RS34015_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="RVR_RS34015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_9518"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_202237768.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.7e-42, bitscore:
                     143.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGPASNPFPSIEMQQRATGRTARWRLSTNENEFGTAPSAVRALI
                     SCAQDAHRYPDCAHQALRGALARRHGVDEDAVLVATGIDGLLAQVCRALLRPGAAVVTT
                     AGTYPTFAYFAEAAGAAVHTVGPRRDRADAEALAEAAHRHRAALVYLAEPDNPLGGALG
                     AERVRRLADQLPEPTVLVVDGAYAEYQAAGRRLDARDVVGRRLLWLRTFSKAYGLAGLR
                     VGYCLYDRTAVSGLEHGLEHYAVGRIAEAAALAALDDDRHLERTVALTAAGRAHYRERL
                     AALGCRPLPSETNFVTFRVPGDPGRTGEVTDALRQRGTYVRQVHSPGRPDLIRLSVGPP
                     AQRAEVLALLCDLL"
     aSDomain        complement(30057..31016)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS34015_Aminotran_1_2.1"
                     /evalue="3.00E-44"
                     /label="RVR_RS34015_Aminotran_1_2.1"
                     /locus_tag="RVR_RS34015"
                     /protein_end="346"
                     /protein_start="26"
                     /score="143.5"
                     /tool="antismash"
                     /translation="LSTNENEFGTAPSAVRALISCAQDAHRYPDCAHQALRGALARRHG
                     VDEDAVLVATGIDGLLAQVCRALLRPGAAVVTTAGTYPTFAYFAEAAGAAVHTVGPRRD
                     RADAEALAEAAHRHRAALVYLAEPDNPLGGALGAERVRRLADQLPEPTVLVVDGAYAEY
                     QAAGRRLDARDVVGRRLLWLRTFSKAYGLAGLRVGYCLYDRTAVSGLEHGLEHYAVGRI
                     AEAAALAALDDDRHLERTVALTAAGRAHYRERLAALGCRPLPSETNFVTFRVPGDPGRT
                     GEVTDALRQRGTYVRQVHSPGRPDLIRLSVGPPAQRAEV"
     misc_feature    complement(31580..31594)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.16"
                     /tool="antismash"
ORIGIN
        1 gcgcgagctg atccaggcgc cgggcgacgg ggagctgtgg cagctcgtcg accgcctggt
       61 ggccgacgat ccgctggtgg accgcatctg gcgggccacc gccgagagcc agccgcccgc
      121 ctacggcacc acgcgcccga tgctcatgcc gccgtggcgg ccgtacaccg gcggcccggt
      181 ggagatcacg gtcacggcac tggtgccggt cagcaggccg gacctgcggc tggtggtggg
      241 cgtcccggcg ccggacgtcg cgccccagtt gcccgaactg cccgagctgc cgtaggggtc
      301 ggaagggccg gcccggccgc atgccgccgg gccggccccg ccggttcccg acggaccccc
      361 tccacccccc acccggatcg ccgggaagag gggcggatcc ctccgcggct cggtgtcgct
      421 cgcgcccgcg ctccctccgg gccgcacccc gagtgcggtt caccacattc cgaggcgtca
      481 atcccgcgct gaaatgggtg aacccgggtg tggcggccat cactgcggca tgctggtcac
      541 cggtggccaa gggtcgtgca cgatggagca attcgtgcct tcgggtccat atcggaccaa
      601 tcgacctgag agtaggggac ggcatgcgga tagctgtggg caagccggtg gtggtgcggg
      661 cgccgcacga ggtgtcgacg gacgcgatag aggcggactg gcttgcgcgt tggccgccgg
      721 agacccgtct gccggagcag cggcgccggt tggcgggcgc gttgcggatg gtgcgctcca
      781 cgacggtggc caaccggccg tgggtggcgc cgctggaggt cgtcggggac ggcgcccgcg
      841 acgcgcgcga ggtgtacgag gcggccttcg ccgcggtggt ggacatggcg gcggaagccg
      901 cgcacggcgc cctcgcggcg gcggggctgg cgccggagga cgtcgactgc gtggtgacga
      961 cccacaccac cagttggacg atcccgcagt tggacgtggc cctcgtcaac cggctgggcc
     1021 tgcggcggga cgtggcgcgg gtgccggccg ccacgctggc ctgcgccggg ggcgcgcacg
     1081 cgctggtcca ggcgacgcgc tacctcgctg ggcggcccga gggcgtggtc ctggtcgtcg
     1141 cgggcgaggc gctgtcgatc ctgcacatgc cctggcgcga gccgacccgg accggtgtgc
     1201 tgtacggggc gctgttcggg gactccgcgg gcgcggcggt ggtggccggc gccgggcgca
     1261 ggcaggagga ctccgcgcgg cggctggtcg cggccggcgg cgggctggtc gcggacgtcg
     1321 agacgtggga gtggttgcag cacggcgaga gcccgtactg gggcgagttg cacccgggcg
     1381 gggtgcccgg cgcggggcgc atcaccttcg agtccaaccg ggacgccacc aagggcgccc
     1441 gcgagaccat gccgcacctg gtgaagtggc tgaacggccg gcaggtggac tgggcggtgg
     1501 tgcatcccgg cgggccgggc atcatcgcgg acaccgtcga cgcgctgggc ctgccgccgg
     1561 aggcgggccg gcactccgcc gactccctgc gcggcggcaa cctcggcggg gtcgccgtcc
     1621 tcgacgtcct gcgccgcacg ctcgacgagg gcccggcccg gggcccgggc ctgctggtgg
     1681 cctacggtcc cggcttcacc gccgacgcgc tcttcctcga cgtcccggag gccgacgtcc
     1741 cggaggccga cgtcccgggc gccgacgtca ccggcaccac cgtcccgggc gccgccactc
     1801 cgtaaccgcc gccgagcccg ccccggcggc gggacgggag gagccggtgc ccccgtgccg
     1861 gcgggtcgga tgcggtgccc cggcccgccg cacgggggtg gacggcccgc agcccgaggc
     1921 gcgttgccgg gccgaccggc gccgctccac cgtgggcggg tgcgaccggg cccgcaaccg
     1981 cgcgcggtac ggcactccgc cggggcgggg cgccgtaccg cgcgggccgc accgcggggt
     2041 tcacagcagc cagcggtggc gccgcacgat cggcagggcg gcccacacgc ggcccaggcc
     2101 ccaggtggtg ccggcggccg cgtaggcgga caggaccatc accagggcgt agacgacgtg
     2161 gtagtccacg aacgggttgg acgacccgct cggggctccg gtggacaggt gctgggcggg
     2221 cggccactcg gccgcccaca tcagcgccat cagcacggtg ccggccacgg ccgtcatgcg
     2281 cagggcgacg ccgccggtga gggcggcgcc gatgccgagc agggcgagca tgaacagcca
     2341 gtcggtccag ccctgcccgg cgatgtggtg gaagaacgac tggagcgggc cggcggacac
     2401 gccggacagg aagcccttgg tgggggagcc gccgtcgacc cagccgcggc cggaggcggt
     2461 ggcgtagtgc cagccgaaga gcttgtcgag gaaggcccat aggaagacga ggccggtggc
     2521 gatccgcacg gcggccagcg acctgcgggc cgcgcccgcg ccggcagccg tgtcgcccgc
     2581 gtggacggcc accgccgacc tccgggtcgg caggcggaat ccggtgcgct gccgggggtg
     2641 ctcgtggacg gccatgatga ctccctgatc gatggcgggg gtgctcggta cgccctcact
     2701 gtcctgcgcg tcacgaccgg gccgcagggg gcccagggcc ccgccgcggg ggccgaacgg
     2761 ccctgcccgc gaggtcggtc gggcccggcg cgctgtcccg ccccggcccg cggcgccggc
     2821 ccgggccgtc gtccggcccg gtcccgttcc ggggcggcgg cacgaccgcc accgggcagc
     2881 gcgcgtgccg cagcagcagg tcggcgaccg ggccgggcgg cgggctcgtc cagcgggcgt
     2941 gccggcgggc gccgacgact atcaggcccg cgccctcggt tgccttcgcc aactcgccgc
     3001 gcggcaggca tcgaggcgcg gcggtgcccg tgccggtgcg gcgccggtag gtccacgggt
     3061 gcaggacagc caccgtggtg ccgcgcaact ccgcctcctg gaaggcgaac agggcggcgt
     3121 ccgcgtcggc gtcgtcctcc accgcgagca gcacccggcc ggtacggcgg tcgcggacgc
     3181 gagggcgcgg ctgcatcccg cgcaccacga ccagcggtgc ggcggcgcgg gccgccaccc
     3241 gccgggccac cgagtgcgcc agcagcccgg cgccgccgcc caccgcgcgg gcgcccacga
     3301 ccgtgagctg cgcgtggcgg cccagccgga cgaggacgtc ggccgggtcg cccgtggcgg
     3361 acgacgcggt cacggtcaga ccggggcgga gccgggcggc gtgcgcgacc gcggcgcgca
     3421 gcaccggccc ggcctcggcc ggatcggccg cgcaggccag cagttcgagg cgggcaccgc
     3481 gcagccgcgc ctcggcggcg gcggtctcca gggcgaggaa ggacgtcacg gatccgtcga
     3541 tccccacgag gacgcgtggt gggctcatgg ccgctccttc tggtcgcggt gcgggaagcg
     3601 cgcgggtgtc gccggcgggt gtcgccggcc acgatcctcg gccgcgccgc cgcgggcggg
     3661 cagggccgtt cgcggcgttc cggccgatcg atccgccctc ttcgaggggc cgttcggccc
     3721 tggtgcgggc aggcaccggc cgcgcaccga ccgggcgggt ggggcgtcgc ggtccggcgg
     3781 ggtgcgcggg tgaagggcgc gcccggggcg cgggtccgcg gcagggccgg ggccggccgc
     3841 ctgtcacagg acgaccgcgg cgaccgcggc ggcggggcgc gcggaaaggg cggctgtcgt
     3901 gatatctcct caccaatggt ggaaaatgca cgtgttgccc agaccggagt gggcggcgac
     3961 gacgagagga cgcggatggc gcgccggcag gagccgctgt tcaccgtgga cggcatcggc
     4021 cgtgtgacgt cgtggagcgc tgccgcggca cgacgtttcg cgcacggcga ggaggcggcg
     4081 ctgggacgcc cggcggacgc cctgatcagg tcggccgccc tggggccgga cccggccggg
     4141 ggcgacccgg ggctgctcgc cgtgccgctg gaggaggacg gcgcctgggc cctgtacgcc
     4201 cagccgcgcg gcccccaggg cctcgacgcc gccatcgagg acgcgctgct gcgggcgctg
     4261 ctgtccgagt cgcagctgag catcgtggtg ctggacacgg acctgaggct ggtccgggtc
     4321 agcatggcca cccaggcgtt gcgacgcccg ggcgccgaca tcatgggcaa gcgcgtcgac
     4381 gaggcgtatc ccctggaccg cccgcaggag gaactggcgg tgctggaacg ggtgctgagc
     4441 accggtgagc cggtgtactc ccggctcgtc ggcaccgcgg tggccggccg taccgggcgg
     4501 cggttcttct cggcctccgc gttccggctg agccggccgg cgggcgaggt catcggggtc
     4561 gccgtcacgc tcctcgacgt cacccggcgg gagcgcgacc acgtgcgccg tcaggcggtg
     4621 tcgcgggtcc gccaggaggt ggggcggtcg ctgggcctgg cgcggacctg cgaggacctc
     4681 gcgggcgcgc tggtgccgga gttcgccgac atcgtgctgg tggcgctggc cgagcaggtg
     4741 accgcggggg acaacccgcc gtccatgccc gccgaccccg cggcgctcct gctgcggacg
     4801 gtggcggtgc agggcagggc cgacggggcc gacgggcgta agacaggcgg cgcggaccac
     4861 gccgaggacg gcggacgcgg cggagacggc gcagacggcg cagacgcggg ggacgccccg
     4921 gggatcgagt ggatcgaggc cgtcggggac atcggcgaca tcggggacgt cgaggccgtc
     4981 gaacgggagt cgtccttcgc gcaggcggtc accgagggac gtccggtgct gcgcaccacg
     5041 cgccgcgccg cgcacctgct ggacctcccc gcccacgacg agatcctgcg cgcggccggc
     5101 gcgcacagca tggtcgtgat cccgctggcg gtccggggcc ggctgctggg actcgcggtc
     5161 gccgtccgga ccggggactc cgcgcgctac ctccgggcgg acctggcggc cgccgaggag
     5221 atcggcctgc acaccgcgct gtgcctggag aacgcccgcc gcagcgcggt cgccagggtg
     5281 atcgcctcca ccgtgcagcg ccggttcctg cccgagcgcc cccggtccgc cctcggcgtg
     5341 gagaccgcgt tcgtggcgtt gtccccgccg tcccggaagg gcgcctggtt cgacgtcatc
     5401 ccgctgtccg gcgcccgctg cgccctggcc acgggcgaga tcggccgggg cggcacggcc
     5461 tcgctgacgg cgatgggccg gctgcggacc acgctgcgcg ccctggcgga cctggagttg
     5521 cagccggacg aggtcctcgc ccggctcagc gacaccgtgg cgggcatccc gtcggacgcc
     5581 gcgctgcccg aggagaccgg cgcgctctcc gtggcctgca cctacggcgt ctacgacccg
     5641 gcgacgagcg tgttcacggt gtcctgcgcg ggacagccgg cgccccgggt gatcgcgccg
     5701 gacggcggcg tggtccggct gggcgaggca gtcgggccgc ggctgggcgg cgagggcatg
     5761 gagccgttcg gcatggtcac ccacagcgtg ccccacggcg cgacgctcct gctggccagt
     5821 gcggacttcg acgaagtgct ggacagtggc ggtgagctgc ggcaggcgct gcgcacctcc
     5881 gggtccgtcc aggacctcgc caacgcgctc ttcgtcaaac tcgcgccgca gccggggcgg
     5941 tccggcaccg ccatgctcgc ccgcaccaac cggctcggca ccgaccgcac catcgcctgg
     6001 gaactccccg cggcggacga ggcggcgtcc aaggcgcgcc ggctcacccg gcaatggctg
     6061 cgcgaccgtt ccgccacggt gacggcggag accgtcgagt cggcggagct gctggtcagc
     6121 gagttggtga ccaacgccgt ccggtacggc gcgcccccga tcacgctgcg cctgaccctc
     6181 aacgacgccc tgaccgtcga ggtgcgggac caccgcaccg ccacccccag catccggcac
     6241 gcacgggtca ccgacgaggg aggacgcggc ctgctcatcg tgtcccacct gtccggcaag
     6301 tggggcaccc gccgggtgga ggagggcaag gcggtgtggg ccgagcagtc catgacctga
     6361 gcgggcccat gctccgaccg agccgaaagg caggcgcgat gcccggcatg atcgtgcctc
     6421 gacgtgagcc gtcgtacgac tccgccgccg cgtcggcccg cgccgccgcc ggggtcaggc
     6481 gtccggcagg cagcggcaca cgagcggcgc cgtcccgacc aggcgcccgg tcccgcagtg
     6541 cgcggtcgag cggggcgccc gaccgcgccc acgggtaggc ggatgcaggg tcgcggcggc
     6601 ggggcgggcg ggagcccgcg gcggcagggc ggcggccctc gtcggacccc gcatcgcgtg
     6661 gtccgctcct ggtcgtcagt cgagctgcgc gagcagatcg gtggcgtagt cgcacagggc
     6721 cgaacggtgg gggctcccgg tcttcgcgat gaggttggcg acgtgcttct ccaccgtccg
     6781 cggcgagatg tacagccgct cggcgatctc ctggttgccc aggcgcggcg cgaggagcac
     6841 gaacacctcg tactcgcgcg cggtcaggcc ctggctgcgc agcggggccg ggacgcccgg
     6901 ggtgccgtgg cgccgctgcc ggaccgtcgc acccgcccgg cgcagcaggt cgcggcaact
     6961 gttggccacg gccggcacgc ccgcgccgtg gaagtactcc tcggcgtcgc gcagccagcc
     7021 caccggatcg ccccagccgt cggccagtgc caccggcgcc accagccgct ggccgagccg
     7081 gcgggccatc aggaacggct cgcccgcctc ccgcgcctgc gccaccgcgg cctccgcccg
     7141 cgccccacgg ccggcccggc cctcgtgcac cgcgaaggcg agccgctcga actgccggtt
     7201 ccacggcagc gccgcgttgg ggtcggccgc gatcgccgcg tgctcgtcgg gatccgcctg
     7261 cccggtcagc gcgcgcagca gcgggcgcag tccgtagcgg ccgttgaggt agtggacgga
     7321 agggttcccc tgctcccagg cgaacgcctc gtcgagttcg cgcagcgccc ggtcgtggtc
     7381 ctcctccagc agcgcgcaga tggcgcggct gccgaacgcc tgcggcgact ggagcgactg
     7441 ctcaccgccc cagcggcgga actcggccag ttcctgctcc atctgccggc gcctcccctg
     7501 gtgggcggcc agcgccaccc gggtgagcag cacgaactgg tggttgtcgg cgtccctgag
     7561 ccgggcggtg ccctcggcgc agcggtccgc cagctcccgg gccccggtgt agtcgccgcg
     7621 cagcacctgc tgcatggcca tggtcgcctc ggcccggtac atcagggcca gcgcgccgtg
     7681 gccgagggcg gcgcggtggg cccgctccag ccgggcggag gagccggtgc acatgaagtc
     7741 gttgacgccc agccacatca gggtgtcgag ctgccacgcg gtcaaccggt gctcgttggc
     7801 gagcacgagg cacttctcca ggtaggagtc ggactgctcg aagccgtgcc ggcgcgcgag
     7861 caccgcgagc aactgccacg cctggcagcc gatctccggg agtcccgcgc gctcggcgcc
     7921 gtccgcggcc tgccgggcca gccgctccgc ctcatgggtg cggtcaccgg cgtgctcccg
     7981 caccccggag aggatcaggt gggcctcgac catcttgacc gccggcccca gcgccgctcc
     8041 ggccgccggc ccgtcgccgt cgggtaccag ccgcagcaac tggcggaccc ggcggacccg
     8101 ctcggcggcg tcctcgaacc gcgcggccgt cacggccgcc cacgcgatgc gggcctggag
     8161 ggtggccgcc cggaccgcgt ccagcgcgcc cggaccggcg tccggcagct cgtcggccag
     8221 cgcgcaggcc cggtcgagct ggccgttctc cgccagcgtg aacaccaact gctccaccaa
     8281 cggcgcccgt tcggcggccc ggtccgggcc gggcagcagg tcgagggcgc gttcgagcag
     8341 ggacacggcg gagttgacgg cgccgccggc ctgcgcggac cggccggcct cggcgaagcg
     8401 cagcgcggcg gcccgggcgt ctccggccgt ctcccgcagg gaggcgacca ggacgcacca
     8461 ctcgcccggc agccccgggt gcgcccgctc gatcgcgtcg gcgccccggg cggctatcgc
     8521 ggcgcgctcg gcgggcacga gcgcggcgac cagggcctcg gcggtcagcg cgtgccggaa
     8581 ctcgtaccag tcgcccaccg gacggctggg ggagatgagg tgggcgtcca tgccggcccg
     8641 caggtggacc agcaggtcgc ggtccggcag cccgctgacc gcctggagga cggccagcga
     8701 gaagcggcgg ccgaggaccg cggcgctgtc gagcagggcc cggccgtccg ggctgagccg
     8761 ggcggagcgc tgggagacgc tgtgcaccac ggtgcggggg acatcgatgt ccagatcgcc
     8821 gcagacgtgc caggcgccgc ccggtccgcg gcgcagcacg tccgcggtga tcatgccgct
     8881 cagcagctcc tcgacgacga acgggttgcc gtcggcgtcc ctggtcagcc ggtcgaccac
     8941 ctcctggggc agcacggccg ccgtgtcgtg gggaggcgat ccggtggccg ccagcgcggc
     9001 ctcggccatc gcccgcacct cctcgccgcc cagcgggcgc ggttcgctga ggatcgcgga
     9061 ccggcgctgg gcggcctgcc gggccaactg ctcggccggc cccggctccg ggcggagggt
     9121 ggccagcagg aagatcggct gcccccggag gttgtcgcac aggtactcga tcagggccag
     9181 cgtctcggtg tcggcgtcgt gcaggtcctc caggaccagc aggcagccgg gctgccggtg
     9241 ctgcgtcagg tcccgtccga tggtgaccag cagccgcagc atcgcctcgg cggtctccac
     9301 cggcgaggcc ggcacgcccg catggccggc ggcgcgccac tcgggcagca gcccgcccaa
     9361 cgccgaccgg tacggggcga gttcctccgg ctcggggagg ccgccgaggc ggacgaacga
     9421 cagcagggcc tcggcgatcg gacggaacgg ggtggcggcc gcgccgccgg tggcgccgga
     9481 ccgcccgcgc agcaccgcga ggccgcgggt gaacgcgcgg aacgcgcact ccgcggccag
     9541 tcgcgacttg ccgatcccgg cctcgccgag caggaacacc gcccggccgt ccccgtcacg
     9601 agcggcggcg agaccctcgt cgagcacggc gagttcggcg ccgcgcccga tcaccattgg
     9661 tgatgtgatg agcaccaacg gagggtatcc ccggcccggg tcatctgcca ggggcgggag
     9721 ggctcccgcg cctcagtacc cgcccgtgtc gccccaggag gtgagggtca gggagtaggt
     9781 ggggaagtgg tccgggtcct ctcccgtcga ggcgagcccg gccagcagtt gggcgcggcg
     9841 gccgacgacc gcgccggtgc ccaggcggat gctccccgcc gggtgggcgg cggccgcccc
     9901 ggcccgggcc gtcgggttct tccacgcgtt gaccaggggg ttgtcgctca tcggatgctc
     9961 tcttccttgt ggaggacggg gtggggggta acggggccgg ctaccgcagc agcagcaccg
    10021 acgggacacg ggaggcgaag ccgagttgca gcaactcgtg tccgatgccg gccagaccgg
    10081 tcagcagccc cggactgctg accgcgtcgg gcgtcccgca ccgcgggccg aaccggtcca
    10141 gcgcggccag cagcgcggcc gcgcggggca gggccgtgcc gggttcggcg cggcccgcgc
    10201 cggtcgccgc gaggaggagg tcaagggcgc ccgcctcccc gtggcacaga cagtggtcac
    10261 ctgcggtcgg agctgcggag cgctcgacca cgacgtcgag cagcttagcc aactccggta
    10321 cgtccgccgc gagcgcactg tcggcgaccg ccagcgcggt gcccgacggc ccgtcgcacc
    10381 agccggtccc gaccggctgc gccgcgcacc gcgcggcggc ggtgcgcagc gccgccaggc
    10441 cggccgccgc gtgatcgcga ccgccgccgg ccgcggcgaa ccgcagcagg gcccacccga
    10501 cgccggcggc gccggtgccg aaaccgccgg ccggcagctc gtcgggcgcg cgggcggcga
    10561 gccggtcggc gcaggcgcgc gcggcgcggc cggccgcggc cgagccggtg gcccgctgca
    10621 ccgcgagcat cgccgccagg cagcccgcgt cgccgtccag gacgctcggc tgcgggtcgt
    10681 cgccggccgc ggccgcggcc aggtccaccg cggcggcggt ccagccggcg atctccgcgt
    10741 cgtccagcag cgtggcgagc cggccgagcg cgtaggcgat ccccccgagg ccggcgaaac
    10801 ccgcgccgac ggcgggcagg tcggccggcc ggcccgccag cgcggtgagc aggtccggta
    10861 gcggggtcag cgcgcgccgc gcgaccgagg tgtaccgctc ggtgccggtg agggcggcga
    10921 gctgcgccag gaagagcgcc gtgccgcagt agccgtgcgg caggccggcg ccctgcggct
    10981 ggaccgccca gatccggtcg tcgaggggtt ccaggcacag ccagttcacg cgccggccgt
    11041 cgtcctgcgc gcgggccagg atacggtcgg cgatcccgca ggcggcggcc agcagccgtt
    11101 cggcgtcggg cacggtggcg gccggtacgc cgtgcggcgg taccgcggcg cggggcgcgt
    11161 cgtggcgccg ccgcgtggcg agcgtcgcgc ggatcaccca ctcctggtcg aagcggtccg
    11221 tctcgcccat cgccgcgatc cggcgttcgg cccgggccag accgccctcg gcgaccaggc
    11281 cgtccgccgt cagcgggccg accatcaggc ccgccgtccc gggggagcag gcggccacgg
    11341 ggacgtcgcc ggcccacagt tcggccagtt cggcgctcgc cagcgcgcgc gcccccgggc
    11401 cgtcggccgc gtcacgccac aggacgtcga agagccgctc ccggtcgagc gcctcgcgca
    11461 gcacgtcggg gtgggtggac tcgtccagca ggttcgcgta ccaccgggtg ggacggagca
    11521 ccgcccgcgt cacgtcccgg gtgaagcggg acagcaggcc gccggggccg gtgagttccg
    11581 cgcggtggcc ggcgatcgcg tcgtaccccg cccggaagcc ggcgacgagc aggtccacgt
    11641 gggcggcggg gtcggcctcc gcgtcgcgca gcagcggccg gttggccgag ccgcggaacg
    11701 tccccacggt ccggatcagg tgcatctcgt ccgtcccggg cgccgaccac ccggtcacct
    11761 cctcgggcag cggggtgtcc cggtcgccgc cgaggcccga gacgtccagg acgccgtgct
    11821 cgcccacgag gaagaacggc agcagtgcgg tccgcgcgac cgacgcggtc agcaccgcct
    11881 gcgccgggtc cccgccgccg ggcaggtgca ggtcggggtg gaagagcgtc tccaggtcga
    11941 ccaggacggg ctggtccgca caggcgatca ggttctcgaa gtgcatgtcg gtggcgccga
    12001 gggcgtggac cagcgccagc agcgcgccga gccgccagta gaaccgcccc acctcggccg
    12061 ggcccgtgca cggcgcggtc gcggcgtact cgatccagcc gtagccaggc cgttcgagca
    12121 cggccagccg gcgcagcccc aggccgggca gccgggagtt gaaccagcgg acggtgtcgt
    12181 tgaagtgcgc gtgcacggcg accgggcggg gcttgaacac cacgcgcccg ccgtgctcga
    12241 aggacagcac cgcgaccgcc cggccgccct ggtggcggtc gccggcgccc atgtccaccg
    12301 cgacgagccg gccggggtcg gtgcccgcga ggggaccggc gaccagcgcg ctccggtcgc
    12361 cggcgaagcg ccgcagcagt tcctcccacg tctccacggc ctggtcgcag cactgcgcga
    12421 gcagccgggc cagcaccggg tactcggtga ccagcgcgtg cagcccgggc cgcgccgagg
    12481 tctgccggac gaagtcgcgg aaccgctgtt ccggggtgct gccgcacaac cggccgcgca
    12541 cgcggagcac gttgagttcg agcaccaggg tccggcgggc gatgcgtacg agggcccggc
    12601 tcaactggtc ggcgaagcag ccgcggacgg cggcgaggtc ggcgatgtcc gcgagtccgg
    12661 cgaggtccgc gaggccggcc gggcgggcgg ggccgtcggt gcggtcggtg cggtcggcgc
    12721 cgccaggtct gtcggggccg agcccttcga cggcccgcag cagccgctcg tccgccgtgt
    12781 cggtgaacgg cgcgagcacc gcggcgaagc cctccgacca cgagtccccg gcgggcggcg
    12841 gcggatcgag cggggcgcgc gccagcgcct gctcgacagt agtggcccag cctggcctgc
    12901 cgatccgccc ggccagggcc gcgggctcct cggcgagcag ggcgcgcaag ccgccctcgt
    12961 ccagcccggt gtccgccagg cgggcccgca gcagcgcggg cgaggagtag tcggactgcc
    13021 aactctccgt cagactggtg gcgttgacgg gctccggggg tggcggcagc cgctcggcca
    13081 gggccacgcc gccgacccac catgtctgcg gatcgatcac gcccgcgatc ctgccaccag
    13141 cgcctcgcac ctcctatggg gggcggcccc catattccgc ccgggcgggg gccgcggccg
    13201 gcccgcgcgg tggaatgcgg ggggcactcc ccataggaag acgcggccgc gcgggcgagg
    13261 ctcgacccat cacgacgacg ggctcggcgt cggccgccag cggggaagcg ggtggccacg
    13321 tccacggtcc ggctgcacgc ggcgccgcac cggtgcggtg tcgcgctcgg tgcggtgccg
    13381 atgcggtgcc gtgcccgacg cggcgccgta ccggcgcggt cgcggcggcg ctccgacggg
    13441 ggcggcgcac gtccccgccc gggctgcgcc cggaccgcgc cggtacggaa caggggaagc
    13501 gaggtggcag cgggcgtgcg ggaggcgtac ggggccgccc gcgggtccgt cccgcccgac
    13561 ctgcccgacg ccgtggtcct cggcacgtcc acgcaggaac tttggggagg cacgccatga
    13621 gcgatgacca ccaggccgtc gagcggccgg cgcagggccc cggcaccgct caggcacccg
    13681 cggcgggcag ggaatccgct tccggcgccg cgggaggcac ctcctggtcc ggtgccgcgc
    13741 cgcgcgcccg gcggtcggcc gacccggacg ggcgcgtcct cgtcctccgc tccccggccg
    13801 cccgcgcggc cggccggcgc ctcgcccggc agcgccccca ccggaccgtc ctggccttcc
    13861 agcgctccta ccgttccgcg gtgccggcgg cgcgcgagcg ggcccggatg gaggaggtgc
    13921 tgctgggcgg ccggcacccg gcgcaggacg gcgacgcggc ccggctgggg gccgcggtcg
    13981 ccgaggcgac cgccgtcgcg gcggtgatcg aggcgccccg cagacaactc ctgctggcgg
    14041 tggacgcggt gttccgcggc cggttcgcgg aggcgtccgc gctggtggag acggcctggg
    14101 aggacatcga ccggctgcgg ctgcacggcc tcggcagcca cgcgctggcc gtgaaggcgc
    14161 tgatccacgc ccaccagggc gaacgcgacg cgctggccga ggcgtccacc cgcttcgacg
    14221 cctggcgcgg ggaccgcgag gacgaggtcc cgatcgtcga ggggctcggc cacgcggtct
    14281 gcgagctgct gcacggcgcc ggcgacgccg cgcgggcgcg cctgcgccac ctccaccccg
    14341 gggacgacgg ccgcgcgggg ggcggggagc cttccggcac cctccagttg tgcggcccgt
    14401 acggactcac cctgctgctg gactgcctcg acggcacggc gggccgtgac gaccacgcgg
    14461 cgatcgccgc ccacccggcc gcccggctgc cgtggaacgc gcacttcgtc cacctcgccg
    14521 aggccgtggt ggccggccgc gagggcgacg cctccgccgc cgaggccgcg ctcaggcagg
    14581 cgctcgcggc cgccgccggc tacccgccgg cccgccacct cggcctggga ctggtcgccc
    14641 gcgcggccgc ccgcgacggc tggggcgagc cggtccgctg gctccaggag gccgaactct
    14701 tctacgcggc ccacgggatc gaccccgccg tgcgccactg ccgcagcctg ctgcgcgagt
    14761 tgggcgagcg ggtgcggcaa cgccggcacg gcagcgggga cgtgcccgac cggctgtggc
    14821 acctcggggt gaccgtgcgc gagttcgagg tgctggtcct gctcgaccgc cggcacacca
    14881 accgcgagat cgccgcggaa ctccatctgt cgcaccgcac ggtcgaacgc cacgtggcca
    14941 acctcctgga gaagacacag gcgggcaacc gccgcgagct ggccgcgctc ctggcaccgg
    15001 agccgaggga gtcgagggag ccgagggagc ccggggggtt cagggagccg gtcggggtgg
    15061 gcgggtgatc cccgcccgtg tgcccgcgcc caccgtcgcc ggaccgacgg cccgggcgct
    15121 tccgggtggg ccgtccggcg cgacgcccct ccaggtgctc gcggtgctcc aggcgccggg
    15181 ccggggcggt cggacaggat cgccgggccg ggcagcccgg cggtcgcctc gtccaggcgg
    15241 gcggcgaggt cccgtagctg ctcgtcgtcc cgcgggtacg cggtgatgat cttgccgcac
    15301 tgggcgcggt cgtaggtgcc ggaggtcatc tgctcgacgg tccccaggtc acgggccgtc
    15361 ttgaaggcgc acccggcgcg gaccagactc cggcggcgcg gtgcgggacc tccggcgcgg
    15421 agagccgggt cgtcgagacg tgcagcttcc agccctgcac ccgggacgtg tgccgcggcg
    15481 gggtgacccg gcaccagacg ccgtcgtcct cgaccttcca gtcccgctcg tccagcgcgg
    15541 cgagcacgga gcgcaccacg tcttccagag gaaatgtgag caagtgaacc cacttccaac
    15601 gcccggccga cggagccgga cccccggctc gcgaacggcc ccactgcgga ggcgcccgcc
    15661 gcgaccgagc atggggggaa acccctgccc cgaccctccc gcccccgcgt cgtcccgtct
    15721 ccgtcccgtc gccgtctccg tccccgggcc cggcggggcg cgccgggagg gtccggtgcg
    15781 ggagacgggg cgacgggcgg gagcggggga agttgggtgc tcagcaccca tgtccggggc
    15841 gtgggccgct gacatcgtcg gttccggtcg cgcagggcgc cctggtcgcc ctggtcgccc
    15901 cggtcgatcc ggtcgctccg gtccggtcac ggcgcggagc gccgggaacc cgacgcgctc
    15961 cgcggcgccg cggcagcggc cccaccgcac gaacggcgcg cgccgcgtgt ccacgacgag
    16021 ggaggagggt ctcgtgccga cgcatgacga gaacgcgggg aagccgcccg cgcccgcccc
    16081 ctcccggcag tccgccgccc cgcggcccgg ccgccccggt ggctgtgccg accggagcgg
    16141 cccgacggtg cccgcggtcg gccggcgcgc ggaggccacc ccatgagcgt cgacgtgttc
    16201 accttcgccg accccgactt ctacgtgccg ccgtccgccg tcgcggaccg cgggccccac
    16261 ctgcggcccg cagccgcacc ggacggctgg accgccgtca ggaccgggtg gtggaccggg
    16321 tggacccccg cgagcggccc gcggttcggg gacggcgacc tgcgcgtcta cgcctccgcg
    16381 ggccccgaac cgctccagcc ggtcctggac gccttcgcgg cggcgtgctt cgcgcgcggc
    16441 gtccccttcc ggcacgtcgc gaaccaaagc gtccaccacc acctgaacca cccgcgcgga
    16501 tcgcgcgcgc aggccggcag gttctgcgtc gccgcccccg cggacgcggc cgccgcggag
    16561 gacctggtgc gggcgctgca cgcggcggcg gtcttcgcgg cctcggccgc cccggcggcc
    16621 gaggcgcacc agcaggccgc gccgaccgtg cgccacggcc gcgtccccgc gccctcggcg
    16681 tccgccgtcc ggcccgacgg cacacggtcc accgaggact acctgatgaa cgcgcccgcc
    16741 ccgacgccgg tggcaccggc gggcttcgag gtgcggggac tgcgggcggc gtccaccgac
    16801 gggtactcct tcacggcgcg caacgtgatg gacggctccg aggtcttcgt caagcaggcg
    16861 ctcccgcagg cggcgccggc cggggacggg cgctcggcgg ccgaccggct gcgcgcggag
    16921 tggcgcgtgc tggcccgggt ccaccacgag gcccccggcc tgtgcccgcg cccgctggtc
    16981 ttcgtcgagg ggcgtccgta cccctacctg ctggccgagt tggtcgcggg agtgccgctg
    17041 acgtcctggg tggtggcgaa cagcccggtg gccgacccgg ccgcgtccgc gggcgactgg
    17101 tcgcgctacc accggcgcgc cgccgacctg atcgcccgga tcgagcgcga cctgcgccgc
    17161 ctgtggctgc tgggctaccc ggtggacggc gtcgaggccc gcgacgtcct cgtcgaccgc
    17221 gacgacggca tccggctgac cggcggcctc acccgtggca ccgcgtccgg cgcggacacc
    17281 gacggcgccg cacggcgggg cggcgccgac ggcccgtcca ggacggccgc ccgtctggga
    17341 ctgctcctgc tgaccccgct cgcgccggtg gccgagcgca accccggcgt cctcccgcac
    17401 atcctgcgcg acctcaccga gcgcgccccg gtaccgccca ggctatggca cgccgcgacg
    17461 cgcccggccg actcgcgcgc cggggccggg gtcccgcttc ccagcccgga acaggtggac
    17521 gccgacgagc gcggggccct gaccgagctg cgcgaccgcg tcgcggcggg catcctggac
    17581 gcggccgccg accgcccgtg gggtgtcttc ccctccgtcc cgcagggcta cgagaccaac
    17641 acgctgggcg tggcctacgg caccgccggg gtcgtgcacg ccctgcgcac cgccggcgtg
    17701 gacatccccg catggatcac ccggcggctg cgcgaggacg ccctgcgcca ggccggctcc
    17761 cttccgcccg ggctgtactc gggcctggcc ggcatcgcct gggtgctggc cgacctcggg
    17821 ttccaggacg aggcgcgcga cctgctcggc gcggccgacc gccacccgct gacccgcgac
    17881 tcggccaccc tcgcgtgggg cgcgtccggc gtcgccatgg cgcacctggc cctgtacggg
    17941 cacagccgtg acgcgtccca cctcgaccgt gccgtggaac tgacgcggct gccgcagcgg
    18001 tcggcggcgc tgagcgcccg cctcggcccg cacgacatga ccggcctgtt ctacggacgc
    18061 gccggcgtcg cccacgccct ccagcaggtg ggggccgtca ccggcgagga ccgcctgcgg
    18121 cgcggcgcgc tccggctgct gcacgcggaa ctcgaccggg ccaggcagtc ggccggcggc
    18181 gaactggtct tcccggtctc cgcgaaggac cgcaggggca tgtactacct gcactgcggc
    18241 accgccggct tcctcacggc cgcctcccgc gccctcgccg cggcaccgga cgagcggctg
    18301 gcgctggccg tgccccggct ggtggcgaag tcgtcgatca cgtacgtcgc ccacgccggg
    18361 ctcttccagg ggctggccgg gctcgggttc gcgctggccg agtgcggccg gctgctcgac
    18421 gacgagcggg cgcgggccgc gtcgtggagg tcggcgcgca cgctgttcgc gcacgcgctg
    18481 cccagcggcg gcgcggtccg gttcctcggc gacctgcggc tgcggcaaag ctgcgagttg
    18541 tggagcggcg cgtccggcgt gctgctcttc ctctctcacc tgctcgacca gcgcccggac
    18601 ccgctcttca gcgtcgactc cctcgcccgc gacgccgccg ccgcccgcgg ccgcgcgccc
    18661 gcccgccgcg agcccctcgc ccgccgcggc accgccgccc gccgcgccgc cccggccccg
    18721 gcgcgcaccc cccagatgtc cgcccgccaa ccggcggcgc ggaagccgtg aaggcacacg
    18781 agagatcagg agaaccccat gagccaggtg ctgaacctcc aggagatgga aatcccggcc
    18841 cccgagcagg agcaggaagt cgagggcagc tacttcatct gcagcgacgc cagctggttc
    18901 ctctgcgcct gaggcaccgc cggggcgacg cgtccgtgcc acgcgtcgcc ccgcccgccc
    18961 gcgggccgac ctccccgccc gcccgcgggc gcaccgcccc acccgcccca cccgcccgtc
    19021 cacgcccggc agacgcgagg cagcagtgat cgagcagacg tacgcgatgg ccgacgccga
    19081 ctactacgcg cccgtcgaga ccctcaagga ccgcggccgt gagtacgccc cggcgaaggt
    19141 cccggacggc tggcgctcct tcgaccgcta cctgtggcgg tcctgggggc gcgccgggct
    19201 gccgatgccc gaccagggct ggaaggtcca cgtctcggcc cgcgccgagc ggatcgccga
    19261 cgtcctcgac acggtcgccg aggagtgctt cgcgcgggac gtccccttca agcacgtcgc
    19321 ggccgagcgg ttcgtgctgc tgctccagca caagcacgcc tcgcggacgc agagcgggaa
    19381 actcgtcgtg gcctacccgg ccgacgagcg ggcggccgcc gcgctgatga gcgcgctcgc
    19441 cgcccgactg gagtccgaac aggggcagtt catcctcacc gaccgccgct tcggcgactc
    19501 ccgggtggtc cactaccgct acggctcctt cacgccccgg cgccggctcc tgcccgacgg
    19561 caccggcacg ccggtgctgc gcgacggacg cgcccggctc gtcgccgacc ggcgcgagcc
    19621 gaggttccac ctgcctgagg ggatcaccga cccgttcgca gccgggggcg cgcaggcgcc
    19681 cgcggaaacg tccgggacgg cgaaggcggc cgggacggcg gaagccgcgg gccccgtgga
    19741 atccgcgggc accgccgaag ccaagggccc catcgaagcc gcgggcaccg ccgaagccga
    19801 gggccccacg gaagctgcga acaccgcgga accctccttc cacggcttcg ccttcgacca
    19861 cgccgtccgg cacagcaacg ggggaggggc ctacgcgggc cgtgaactcg ccaccggccg
    19921 gaaggtgttc atcaaggagg cccgcgacca caccgggctc tcctgggacg gcctgaccgc
    19981 cgtcgagcgc acccggcgcg agtgggacac cctgcgggcg ctgcacgcgg cgcaccccgg
    20041 catctgcccc gagccgatcg cgtacttccg cgagtgggaa cacgagttcc tggtcaccga
    20101 gttcgtcccc ggcaccacgc tcaacacctg ggtggccgcc cgcagtccgg tgacccgggt
    20161 ggaggcggag ccgccggagg ccgagcgcta cacggccgac tgcgaggcga tcgccgcctc
    20221 gctggaggag caggtgcggg tcctgcacgg tctggggtac ctcttcggcg acgtcagccc
    20281 cggcaacgtg ctggtcggcg acgacggccg gccgcggctg gtggacttcg aggcggcgcg
    20341 ctccctgggg gacaagggcg tctcggtggc caccgacggc tacgcgcccc cggcccgtct
    20401 ggtgcgggac gacccgaccg tcccggacca ctacgggatc tcggcgctcg tccggctgat
    20461 gctcggcccg accttcgcgg tggccgaccg ctacccccgc tcgctggagc acctgcgggc
    20521 cgacctccag gagcggatgg cggtgcccca ggcgctgtgg gggcgcgccg tccgcttcca
    20581 cccggccgac ggcccggcgc tgctgccggg accgcgggag gtggcggccg acccggtgcg
    20641 ccacgtccgc gacctgcggg acgaggtcgc gcgggcgctg acctcgatgg ccgacccgga
    20701 ccgcgcggac acgctgttcc cgaccgtccc cgacgggtac gcgagcaaca ccgtgtgcgt
    20761 cgcctacggt gcggccggcg tcctgcacgc gctgtggcac ggcggcgtcg ccgtggacga
    20821 ggccgtcgtc gcgcgcttcc gccgcgacgc gctggccgcc gcggggagcc tgcccccggg
    20881 gctgcacgtg ggactggcgg gcgtcgcgtg ggtgctggcc gaccacgggt acctcgacga
    20941 ggcgcgcgac ctgctcgcca ccgccaccga gcaccccctg gccacccggc gggccggctt
    21001 cgccgagggc gccgccgggg tggccatggc ccacctgtcg ctcttcgcgc acaccggcga
    21061 ccacgggcac gtcgacaccg ccgagcgcct gctgtccgcg ctcccgccgg acggggaact
    21121 gtccggactg ctcgaccgcg acgacccgac cggatggctg cacggcaggt gcggcatcgc
    21181 ctgggcgctc cacccgctgg cggcggtcac cggcgacgcc cggtacctgg agcgcggggt
    21241 gcggctgctg caccacgaac tcgaccgcgc gatgcccggc ggggcggcgt caccgcactt
    21301 cccggtgtcg gccaccgacc gccggtcgat gccgtacctg ttctgcggga ccgccgggac
    21361 cctgcgcgcc gtctgccgct acaacaccgt ctgccaggac gagcgcctcg cgggcgtcga
    21421 gagcgacctc atgccgcggc tgcgcaccac gtacacggtc atgccgggcc tctaccaggg
    21481 cctggccgga ctggggttcg cgctcgcgga ccacgcgtcc gtccgcggcg acgaggtgtc
    21541 ctcccgcgcc gcgctgcgca ccgcccgggc cctgttcaag tacgcggtcc ccggacccac
    21601 cggggtccgg ttccacggcg agaagctcaa gcggttcagc gcggacctgt ggagcggcgg
    21661 ggcgggcgtc ctgctcttcc tcgaccaggt actggacggc ggcgcggacc ggctgttcag
    21721 cctcgaccgg ctggtcccgg cgggctcctg agccgcgctg cggggcagga accgtcgtgc
    21781 ggacgatcgt ccatcaatcc tggaggtcgg acgggctgaa tggacgtgtt catccgcttt
    21841 cgataggggc gaaccttgcc gcctcgcggc cacggtgtta cgttcccacg tgatcttgtc
    21901 ggacaatctt atgcggggcg gttgccggtc acgcgggccg gtgcccgggt cacggcgccc
    21961 tccgcggcag gcggcgacgc cccaccgcgc gggcacggga cggccccgca cctccggggc
    22021 cgtgaccggg cgcgccgcga cccgccgccg gatcggagac ccgcgtgaac gtacccccga
    22081 gcgacacccc gccgtccgag ccgtcgcctc ggcaccgtcg ggaggccccc ggccggacgg
    22141 ccggcgccgg gcccgcccgc gggaccgtca ggatcgacac cggactggtg tccggcgtcc
    22201 cgggcgcgct gcccggcgtc accgtctacc ggggcatccc ctacgcggcc tccaccgcgg
    22261 ggcccgaccg gtggcgcccg ccgcggccgg cgccgtcctg ggagggcgtg cgcgccgccg
    22321 acaccttcgg cgacgcgcct ccgcaggccg gcaccggttt cgccatgagc gaggactgcc
    22381 tgaacctcaa cgtgtggacg gcggcgtccg ccggcggcga gcggcgcccg gtgtacgtgt
    22441 ggatcttcgg cggcgggttc tccggcggca ggggctccga cccggtgttc gacggctcgg
    22501 tgctcgccgg caagggcctg gtcgtggtga cgttcaacta ccggctgggg gccctcgggt
    22561 tcctcgccac gcccggtctc agccgggagt ccgcgcaccg cgcctcgggc aactacggcc
    22621 tgctcgacca gatcgcggcg ctggagtggg tgcggcggaa catctccgcc ttcggcgggg
    22681 accccgacca ggtctccatc ggcggccagt ccgcgggggc gggctccgcc ggcatgctgt
    22741 ccctgtcgcc gctggccgcc ggcctgttcc ggcgcaccgt cgcccagagc catgcccgcc
    22801 accccggcga cccggaactg cggtacctgg gcacgtcgta ccgccggctg gacgccgccg
    22861 agcggcaggg cgccgcctac gccgccgccc acggcgcgac cacccccgac gagttgcgcg
    22921 ccctgccctg gcaggacctc gacgacgccg ggacgctcgg ggacgacggc gtggacaccc
    22981 ggtcggcggc ccgcccgccg ctgttccggc cggtgctcga cggctgggtg ctgccggccg
    23041 gctaccacga cacgtacgcc cgcggagccc agaacgacgt gtggtacctg gcgggcaaca
    23101 acctcgacga gaccggcgcg gtgccggaga ccgccttcga ccactggcgg cggaccggcc
    23161 gccgggaccg ccccggcgcc ccgcccgtgc acgtgacgct cgacgacttc gtcggctccg
    23221 cgcggcacac ctacggtgcg ctggccatgg agttcctccg gctctacccg gcggcgacgg
    23281 acgacgaggc cgcccgcgcg gccaacgacg ccgtgcggga ccgctcccgt gccaccaccc
    23341 acctgtgggg cacccagtgg gtccggggct gcggccggcc ggtccacacc tacttctgga
    23401 cgcaccggcc ccccggcccg gaccacgaca tccgcggcgc cggccacggc tcggagatcc
    23461 cctacttctt cggcaccctc cacccggccg accagggctg gaccggccgg gaccgggaga
    23521 tcgccgacac gatgtcctcc tacctggcca actacgtcgc cacgggcgac ccgaacggcc
    23581 ccggactgcc cgcctggccc gcctacgacc cgcggacgcc caccgtgatg gaggtcggcg
    23641 cgcacttcgg cccgatcccg gtcgccccgc ccgccgaact cgacttctgg aaacggtact
    23701 tcgccgcgca acagccctgg tagcggcgcc cgtaccggca tcctggggcc ggcctgcggg
    23761 aatccgcgac gccgcgcccg ctcgtgtgcc ggggaggcgg gacatccgga atgtccggcc
    23821 ggcggcggtc tccaccggac tgtgcgaaaa cctccgcagc gtcgtaactg cgcgcatatc
    23881 ttgggcccca ggtgccctgg ccgcgcttcc ggccgcgggc accgccatgc cctcccgcac
    23941 acgaaggaga acccttccgg tgacgagatc cccgaagacc acgccgcccc gccccgcgcg
    24001 agccgagtcc gccgccgcgt caggacgcac cccgtcccgg ctgggcatgc gggtcctgcc
    24061 cgtcggtgcg gccggcgcgc tggtgctggc cggtctggtg atgcactcgg cctccgccgc
    24121 tccgtccccc gacggggtga tcgccgaggt gtacggcggt ggcggcaaca tcggcgccac
    24181 gtacaccagc gacttcgtcg aactggccaa cgccggcacg tccacgctcg acctgagcgg
    24241 ctacagcgtg cagtacctgc gcggtacgcc gaccccgacc tcctcgtggc gcgccaccgc
    24301 gctgtccggc acgctcgccg ggggcggccg gtacctggtc caggagtggt ccaacaccgg
    24361 cggagccgtc tccctttcgg accccgacgc cgtcggcacc atcaacctgt ccgcgaccga
    24421 cggtaccgtc gcgctggtct ccggcaccgc cccgctcacc tgcctgaccg cggccgactg
    24481 cgccgccgac ccccgggtca aggacctggt ggggtacggc tccgcggtcg tccacgaggg
    24541 tgccgggccg gcggcgacgg cggacaacac cacgtccgtg gcccgcggcg actcgctcgc
    24601 cgacaccgac gacaacgccg cggacttcac cgcgggcgcg cccaccccgc agaactccct
    24661 cagcgccggg ggcggcaccg cgggcaccgt cagtgggacg tccagtggga cgtccagtgg
    24721 gacggacgac ggcggcggca ccgtgggtgt cacgagcggg accactgacg gcgggagcgc
    24781 ggacggcggt ggcattgacg gcgggagtgc cgacggcggt ggcatcgacg gcgggagtgc
    24841 cgacggtggg agcgcggacg gtggggggat tgtcggtggg gccgatgacg gcggcaccgt
    24901 gggggtcacc gccgggacca ccgatggagg tgtgaccggg ggcggcaccg cgggcaccgt
    24961 cagcgggacg tccagtggga cggacgacgg cggcggcacc gtgggtgtca cgagcgggac
    25021 cactgacggt gggagcgcgg acggcggtgg tattgacggt gggagtgcgg acggcggtgg
    25081 catcgacggc gggagtgccg acggtgggag tgcggacggt ggggggattg tcggtggggc
    25141 cgatgacggc ggcaccgtgg gggtcaccgc cgggaccacc gatggaggtg tgaccggggg
    25201 cggcaccgcg ggcaccgtca gcgggaccac cggcggctga cggtccgtca tgacgtgagg
    25261 cgcgcagggg tggggcgtcg gctccgtgct cactccagcg tgcgcagcgc ccgcgcggcg
    25321 atctcccggc cgatgggcag cgacgcggtg gccgcgggtg acggggcgtt gagcacgtgg
    25381 acgaaggggc cggcgccggt gaagaggaag tcgtccacga gggtcccgtc cgcccgcacc
    25441 gcctgggccc ggacacccgc cggcgccctc acgaggtcgt tccgggtgac gtccggcagc
    25501 atccggcgga ccgcggccgt gaacgccgtc ttggacgccg agcgccacaa ctcgccgacc
    25561 tcccggcgcc agtggcggcg ggcgacgcgg cgcaaccccg gccagccggc gatgtccgcg
    25621 gcctcgcggg cccggaagtc ccgccaccgg tagccctccc gggccgccgc gaggaccgcg
    25681 ttgggcccca cgtggacccc gccgtgcacg tcccgggtga ggtggacgcc caggaacggg
    25741 aaggcggggt ccggcaccgg gtacaccagg ttccgtacga gcccgcggct ccgctccgcc
    25801 agttcgtagt actcgccgcg gaaggggatg atgcgcacgc cgggttcgtc cccggccatc
    25861 cgggcgaccc ggtcgctgtg caggccggcg cagttgacca ggaccccggc ccggacctcc
    25921 ccggcggtgg tgtgcaccat gacgccgtcc ggtgcgcggg tgagggcgag cacctcgcag
    25981 ccgaggtgga cctccgcccc gtcgcgcgcg gccagttcgg cgaaccggcg ggcgaccgcc
    26041 gggtagtccg cgaccccggt ggtgcccacg tgcacggcgg ccagcccccg cacgtgcggc
    26101 tcgtgctcgg cgatctcccg gacgccgagg gtgcgcaccg ggatgccgtg ctgctcgcca
    26161 cgccgggcca ggtcggccag gcgcggcagc tccggggccg tcgtcgccac gatcagcttg
    26221 ccggtgacct cgtgcgcgat gccgtgggcg gcgcagaact ccaccatctc ccgcgcccct
    26281 cgcagcgcga accgcgcctt gaacgagccg gggcggtagt agatgccgct gtggatcacc
    26341 ccgctgttgc gcccgctctg gtggcgggcg agggcgggct ccttctccag caccgccacg
    26401 gacctgccgg gcgcggcccg ggtcacggcg tacgccgtgg acaggccgat gatgccgcca
    26461 ccgatcacga ccacgtcgta gtggctccgc acggtcgcct cctcgcgtct cctcgtcggc
    26521 cgcgggtccc cgcgcgggac gtgcggctca tgcggcgccg gccgggaagc ccccgtcgaa
    26581 ggccgggacc agctccgaga accaggccgc ggcggggtcg aacttcgcgt agaacgggcg
    26641 gcccaccgcg tccgcgtcac ggcactggat gtagtgcagt gcgaacacct tctcacccgc
    26701 gacgtccacg acgccgtcca cgcagacctt tcccgaggtc gtggacatcg acggcccgcg
    26761 caccgtgcgg cacagcccgc tgacgtcccg gtaggcgcgc cggaagatgt cgtgggcgtc
    26821 ggcgagggac accttgaagt actcctgcgg gccggtgtcc cgctcgacga acatgtagta
    26881 gggcaccatg cccatgctga cctgcctgct ccacatcgcg gaccagaccg cggggtcgtc
    26941 gttgatgtac cgcatcagcg gcgcctgggt gcggatgctc gcccccgcgc cgcgcagccg
    27001 ccgtaccgcc tgttcgacga ccggggtccg cagttcccgc gggtgggaga agtgggccat
    27061 caccgagagg tccttgcccg agcgggacac ctcctcgaag agccgcagca tgtcgtcggc
    27121 gtccgggtcg gtggtgaact tgtagggcca gtagctgagg gccttcgtgc cgatgcggag
    27181 ggattccaac tggtcgagtt cgagcagcgg ttcgacgtag cggcgcagca cgcccgcccg
    27241 catgatcatc gggtcgccgc cggtgaacag cacgttgctc acctcggggt ggtcggcgag
    27301 gtagcgcttc aactgcccga tgtcgccgct ggccatcttc aggtccgcgt cccccacgaa
    27361 ctgggcccag cggaagcagt acgtgcagta cgagtggcag gtctggccct gcttggggaa
    27421 gaacagcacg gtctcgcggt acttgtgctg catgcccggc agcggcgcgc ccgcgtgccg
    27481 ggggacgttc agttcgagct ggccggccgg gtgcgggttc agccggcggc gcaccgcgtt
    27541 cgccgcggct gccacctcct tcggcgcggc gcccctcgtc agcaggtcgg cgatgcgtgc
    27601 cacgtccccg gccggcagca tgtcctcttg agggaagacc aggcggtaga tcgggtcgtc
    27661 cggcaccgcg ctccagtcga tcagctcctc gacgacgtag cggttcgtcc ggaacggcag
    27721 cacctcggcg acggcgcgta tcgcggtgac ctggctcccg gtgaagccgg ccgcgccgac
    27781 gagttcggcg agccggccgg cggtgacggc ggagaacacc ggcgcggcgg ggaagccggg
    27841 tacggccggg tcactcgagc cctggacgac ggtcatggac ggtcccttct ctgatggtgg
    27901 ctggaccact gctgcccccg gtgcgggtgc gcagggtggc gaggacgacg acgcccaccg
    27961 cgaggcccac gagtacggcg gagggccgca gcggttcgtc gaggaggacg gccgcgaaga
    28021 gcatggtgag caccggttgc aggagctgga cctggctcac cttggccacc ccgccggcgg
    28081 acagcccccg gtaccagcag aagaacgaca gcagcgagct gcccagggcc aggtagacga
    28141 aggcggccgc accgcgcgcg tccagggacg gccctggcga cggccaggcc agcgccaccg
    28201 ccagggccgc cggcggggtg ccggcgacca gggcccagga ggtgaccacc cagcccggca
    28261 cgtcccgggc cagcacgccc ccctccgcgt agccgaggga gcaggccacg accgccgcca
    28321 gcagctcggc gtcgccgacg tgcagtccgc cgccgaagcc cagcaggacg tagccgcaca
    28381 cgagcgcggt gcccagcgcg cagcagaccc agaacgtggc cgagggccgc tcccggcccc
    28441 gcaggacggc catcaccgcg gtcgtggccg gcagcagggc caccaccacg gcggcgtggc
    28501 tcgccgagac cgagcgcagg gcgtgcgcgg tcagcagcgg gaagccgatg acggtgccca
    28561 gggacgtgac gaccacgccg cgcacgtggt gtctcggcgg cagcagcgga cgctgccggg
    28621 cgagcagcag cgctcccgcg gggatcacgg cgagcaggga ccgccccggg cccacgagtt
    28681 cgggcgggag cgattccgtg cccactcggg tcaccggcag ggtgaggctg aacccgagca
    28741 cccccaggaa gccgtagagg aatccctgga ggtccggggg gagggtgcgt ttcatcgggg
    28801 gcggtcatcc gtccggtggg gtgggccggt cagctcgtct gggcgcgcag ctcgtcggcg
    28861 cgcaccggtt gctcccaggg caggccgccg gtgcgtccga agtggccgaa ggtcgcggtg
    28921 ggccggaagg aggtgtggcg caggcgcagt ctgctgatgg tcgcatcgac ccgcaggtcg
    28981 gtgagagagc gcaacgcgga ggtcagcttg gccggatcga cccgctcggt accggagcag
    29041 tccacctcga accacaccgg ctcggggcgt ccgatcgcgt aggccatgcc gacctggcag
    29101 cgcgccgcga gtccggccgc gacggcggtc agggcgagct ggcgcgccac gtaggcgccc
    29161 gaccggtcca ccttcgtggc gtccttgccg gagaagcagc cgccgccgtg gcgggcgagg
    29221 ccgccgtagg tgtcgaccat gagcttgcgg ccggtgagcc ccgcgtcggc cgcggtgccc
    29281 ccgaccacga acgacccggc cgggttgacc tcggcccatt ccaccggcag gtcacgcgcc
    29341 gccaggacgg gcccgaccac ctgttccgcg cagaactccc ggaccgcgtc gagcggccgg
    29401 cccgcggcgt gctggacgga cagcacgacc cggccgcgcg gggagcggtc gccgccggcg
    29461 acctccacct gcaccttgcc gtcggggccg agcccggagt ccggcgaccg cagccgctcc
    29521 tcggccaggg cccgggtcag cccgtgggcc agcacgcaac tgagcgggag cagttccggt
    29581 gtctcgtcgc aggcgtagcc gtaaacgacg ccggagtcgc cggagccgcc ctcgtcgacg
    29641 ccggagccga tctcccggga ctggtggtcc aggacgacgg tgacggggct gcgcgccgcg
    29701 tcgatgccgt gcacggccac gtcgcggtac ccgacgtccg acaggacgcc gcgcgccacc
    29761 gcctcgacgt ccaccgcccc ggcggcggtc acctgtccgg tgaccaggac gtggtcccgg
    29821 gtcaccatga cctcgcagtt gacgcgcgcg tacgggtcgg cggcgaggta ggcgtcgagc
    29881 acggcgtcgg agatctggtc ggcgaccttg tcggggtggc cgggcgtgac ggactcggcg
    29941 atctgcgacc agggcgggcc ggaggagggg gacggcatgg cgggactcgc aatctgcact
    30001 cgccggtgcg gggtcggggt ggggtgcggt cagagcaggt cgcacagcag cgcgaggacc
    30061 tcggcgcgtt gggccggagg gccgaccgac aggcggatca ggtccggccg cccgggggag
    30121 tgcacctgcc ggacgtaggt cccgcgctgc cgcagggcgt cggtcacctc cccggtgcgc
    30181 ccgggatcgc ccggtacccg gaaggtcacg aagttcgtct cggacggcag cgggcggcag
    30241 ccgagcgccg ccagccgttc gcggtagtgg gcgcggccgg ccgcggtgag ggcaaccgtc
    30301 cgctccaggt gccggtcgtc gtcgagggcg gcgagcgcgg ccgcctcagc gatccggccg
    30361 accgcgtagt gctccaggcc gtgttccagg ccggacaccg ccgtgcggtc gtacaggcag
    30421 tagcccaccc gcagtcccgc caggccgtag gccttggaga aggtgcgcag ccacagcagg
    30481 cggcgcccca ccacgtcccg cgcgtccagc cggcggcccg cggcctggta ctccgcgtag
    30541 gccccgtcca cgacgagcac ggtcggctcg gggagctggt cggcgagccg gcggacccgc
    30601 tcggcgccga gcgcgccgcc cagcgggttg tcgggttcgg cgaggtagac cagggccgcc
    30661 cggtgccggt gcgctgcctc ggccagcgcc tcggcgtcgg cgcggtcccg gcgggggccg
    30721 acggtgtgga ccgcggcccc ggccgcctcg gcgaagtagg cgaacgtcgg ataggtgccc
    30781 gccgtggtga ccaccgcggc gcccgggcgc agcagcgcgc ggcacacctg ggccagcagg
    30841 ccgtcgatgc cggtcgccac caggaccgcg tcctcgtcca ccccgtgccg gcgggccagc
    30901 gcaccgcgca gcgcctggtg ggcgcagtcc gggtagcggt gcgcgtcctg cgcgcaggag
    30961 atcagggccc gcacggcgga gggcgcggtg ccgaactcgt tctcgttggt ggacaggcgc
    31021 caccgcgcgg tacggccggt ggcacgctgc tgcatctcga tcgaggggaa cgggttcgac
    31081 gcggggccgg ccatctcagg gccccccggt gacggccggg aggtgctcga cctccagcag
    31141 gtcggcgagg aactcgttgt accggcgcat ggcgagcatc cgcagcgccg cgccctgggc
    31201 cagctccatg ccggcggccg ggtcgtgccg gacgatcggg gtgacgacgt ggtccagcca
    31261 ctcgggcccg tgctcggcgt cgccggcgac gtggttgacg aagaactgga acccgtcgtc
    31321 ggggtcgaac cccagccgtc gcaggccccg gacgacgatg tcgtcgcggt ccacgtcgaa
    31381 cagctcgggc atggccaggc tgcccagcgc cttgaagtgg tggcggcggt tggtgccgag
    31441 cgtgaagtag aggttgaacc cggcgtaggg ccgccagtcc tcccacgggg gcaggtgcgg
    31501 cagggccacg ccgagccggc gcagcgcacc ggagaactgg acggtgtggg cggccggccc
    31561 gtcaccggcg ccgcactcgt cccacaagtg gtggccgatc tcctgcttga cgctctccat
    31621 gaagtgggtc tgggccagca ccagggcgtc gaagaaccgg tagttgaggt agccgtcggc
    31681 ctggaggaac cgggtcatct gcgccgcgga cgccgtgtgc tccaggtgcc cttccaccgc
    31741 ccggtccaga g
//
