LOCUS       NZ_AP018365            26848 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Streptomyces sp. SN-593 chromosome.
ACCESSION   NZ_AP018365
VERSION     NZ_AP018365.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. SN-593
  ORGANISM  Streptomyces sp. SN-593
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Panthee,S., Kito,N., Hayashi,T., Shimizu,T., Ishikawa,J.,
            Hamamoto,H., Osada,H. and Takahashi,S.
  TITLE     beta-carboline chemical signals induce reveromycin production
            through a LuxR family regulator in Streptomyces sp. SN-593
  JOURNAL   Sci Rep 10 (1), 10230 (2020)
   PUBMED   32576869
  REMARK    DOI:10.1038/s41598-020-66974-y Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Takahashi,S., Toyoda,A., Sekiyama,Y., Takagi,H., Nogawa,T.,
            Uramoto,M., Suzuki,R., Koshino,H., Kumano,T., Panthee,S., Dairi,T.,
            Ishikawa,J., Ikeda,H., Sakaki,Y. and Osada,H.
  TITLE     Reveromycin A biosynthesis uses RevG and RevJ for stereospecific
            spiroacetal formation
  JOURNAL   Nat Chem Biol 7 (7), 461-468 (2011)
   PUBMED   21642985
  REMARK    Publication Status: Online-Only
REFERENCE   3
  AUTHORS   Panthee,S., Takahashi,S., Takagi,H., Nogawa,T., Oowada,E.,
            Uramoto,M. and Osada,H.
  TITLE     Furaquinocins I and J: novel polyketide isoprenoid hybrid compounds
            from Streptomyces reveromyceticus SN-593
  JOURNAL   J. Antibiot. 64, 509-513 (2011)
REFERENCE   4
  AUTHORS   Takahashi,S., Takagi,H., Toyoda,A., Uramoto,M., Nogawa,T., Ueki,M.,
            Sakaki,Y. and Osada,H.
  TITLE     Biochemical characterization of a novel indole prenyltransferase
            from Streptomyces sp. SN-593
  JOURNAL   J Bacteriol 192 (11), 2839-2851 (2010)
   PUBMED   20348259
REFERENCE   5  (bases 1 to 8833490)
  AUTHORS   Takahashi,S., Ueki,M., Toyoda,A., Ishikawa,J., Sakaki,Y. and
            Osada,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2017) Contact:Shunji Takahashi Chemical Biology
            Research Group, RIKEN Center for Sustainable Resource Science
            (CSRS); Hirosawa 2-1, Wako, Saitama 351-0198, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Phrap v. 0.990329
            Genome Coverage                   :: 16x
            Sequencing Technology             :: ABI 3730
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016756395.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 03:58:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,420
            CDSs (total)                      :: 7,334
            Genes (coding)                    :: 7,181
            CDSs (with protein)               :: 7,181
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 153
            CDSs (without protein)            :: 153
            Pseudo Genes (ambiguous residues) :: 0 of 153
            Pseudo Genes (frameshifted)       :: 35 of 153
            Pseudo Genes (incomplete)         :: 136 of 153
            Pseudo Genes (internal stop)      :: 8 of 153
            Pseudo Genes (multiple problems)  :: 25 of 153
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:29:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7083209
            Orig. end                         :: 7110057
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP018365.1.
            This work was done in collaboration with Shunji Takahashi, Masashi
            Ueki, Atsushi Toyoda, Yoshiyuki Sakaki and Hiroyuki Osada (RIKEN)
            and Jun Ishikawa (National Institute of Infectious Diseases).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26848
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="26"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26848
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26848
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16848](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16848
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(353..961)
                     /gene="idi"
                     /locus_tag="RVR_RS30660"
                     /old_locus_tag="RVR_8523"
     CDS             complement(353..961)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952075.1"
                     /locus_tag="RVR_RS30660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8523"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_202237152.1"
                     /transl_table=11
                     /translation="MPTSPATGRPGSPSTVPSPDGVAEPIMLELVDENGVTIGTAEKLS
                     AHLAPGRLHRAFSVFLFDDEGRLLLQRRALSKYHSPGVWSNTCCGHPYPGEQPFVAAAR
                     RTAEELGVAPALMREAGTVRYNHPDPASGLVEQEYNHLYVGVVRAPLLPDPDEIGETLF
                     VTPGELAKLREDGPFSAWFQTVLDAALPAVREVAGTAGW"
     gene            complement(1091..2053)
                     /locus_tag="RVR_RS30665"
                     /old_locus_tag="RVR_8525"
     CDS             complement(1091..2053)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386154.1"
                     /locus_tag="RVR_RS30665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8525"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_202237153.1"
                     /transl_table=11
                     /translation="MGAGSGHHHGHGHGHSHGHQHGTATTAGGAHRGRLRIALTITLLV
                     LATEVAGSLVTGSLALLADAGHMATDAAGLAMALLAVHVAARPPSERRTFGYARAEILA
                     AGLNALLLLAVGVFIFYEGVRRLITPHGIDGGATIVFGVIGLVANSVSLAVLMAGQKES
                     LNVRAAFLEVMADAFGSLAVVAAAVVYLLTGWRQADAVASLLIGVLIVPRTWQLMREAL
                     DVLLEAAPRGVDMRQVRRHIEGLAGVEGLHDLHAWTITSGLPVLSAHVVVSQDVLDAVG
                     YEKMLHDLQGCLGTHFDVAHCTFQLEPAGHAAHEPGMCR"
     misc_feature    complement(2192..2210)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.4"
                     /tool="antismash"
     misc_feature    complement(2250..2264)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.44"
                     /tool="antismash"
     misc_feature    complement(2277..2291)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     misc_feature    2277..2292
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    complement(2280..2295)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.75"
                     /tool="antismash"
     gene            2436..4322
                     /locus_tag="RVR_RS30670"
                     /old_locus_tag="RVR_8528"
     CDS             2436..4322
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="RVR_RS30670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8528"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_202239392.1"
                     /transl_table=11
                     /translation="MSTAILTGPPDAGTPSPLADDLRALGFQVVEADGPRAVAERVAGA
                     PPAERVAVVDRRFRGHRHALRLALTDPRFDAGAVPGALAVQAAARPALSRALHELAGGA
                     DAAAPAAGGPAAPQGGAPTATVADGDVLADVLAGELGRQGAEPYRPELGVLVARVARGP
                     QEEAAAAEAVAGVDEEAVRLRSAVKSRDGFFTTHCISPYSRYIARWCARRGLTPNQVTT
                     ASLLVALIAAGCAATGTRGGYVAAGVLLLASFVLDCTDGQLARYSLQYSTLGAWLDATF
                     DRAKEYAYYAGLALGAARGGHDDVWALALGAMVLQTCRHVVDFAFNEANHDAAANTSPT
                     AALSGRLDSVGWTVWVRRMIVLPIGERWFLIAVLTAATTPRVTFVVLLIGCALAACYTT
                     AGRVLRSLTRKARRTDRAAQALADLADSGPLAEAVARVAAPLARRLPAFAPPLLAAIGA
                     GALTATAALATRGTWWVVAAAVLYVVTSAIAVARPLKGALDWLVPPFFRAGEYGAVLAL
                     AAVSEVNGALPAAFGLVAAVAYHHYDTVYRIRGGTGAPPRALVRAAGGHEGRALLVAVL
                     SAVLVTGSRHDGFTAALTVLAAVLALLVLTESIRFWVSSGAPAVHDESGEPA"
     gene            4319..5071
                     /locus_tag="RVR_RS30675"
                     /old_locus_tag="RVR_8529"
     CDS             4319..5071
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640650.1"
                     /locus_tag="RVR_RS30675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8529"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_202237154.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.7e-09, bitscore:
                     36.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPDGAADGPTVLDLTLG
                     NFAAVGITRAAVVVGYRKEAVYARKEALEARYGVELTLVDNDKAEEWNNAYSLWCARDV
                     LREGVILANGDTVHPVSVERTLLAARGDGRRIILALDTAKKLADEEMKVVAEPGRGVRR
                     ITKLMDPAEATGEYIGVTLIEADAAADLADALKATYERDPDLYYEDGYQELVDRGHVLD
                     VAPVGDIPWVEIDNHADLARGREIACQY"
     gene            5059..6120
                     /locus_tag="RVR_RS30680"
                     /old_locus_tag="RVR_8530"
     CDS             5059..6120
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="RVR_RS30680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8530"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_202237155.1"
                     /sec_met_domain="Fe-ADH (E-value: 3.6e-20, bitscore: 70.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.3e-06, bitscore:
                     26.5, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRGGALADLSRLLADERISTSGKIAVAVSD
                     GSGARLRERLAPELPGADWFPVAAGTIDAAVKLADAMRGQRYDAVVALGGGKIIDAAKY
                     AAARVGLPMVAVATNLSHDGICSPISTLDNDNGRGSYGVPGPIAVVIDLDVIREAPSRY
                     LRAGIGDAVSNLSALADWELSHRETGERIDGLAAAMARGAGEAVLRHPGTVADDDFLVI
                     LAEGLVLTGIAMSISGDSRPSSGACHEISHAFDLLHPQRAAAHGEQVGIGAAFAMHLRG
                     AREESALIADTLRRHGLPVLPEQIGFSAQEFVEAVRYAPQTRPGRHTILEHLDLSATEI
                     RDAYADYAKTISS"
     gene            6098..6877
                     /locus_tag="RVR_RS30685"
                     /old_locus_tag="RVR_8531"
     CDS             6098..6877
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="RVR_RS30685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8531"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_202237156.1"
                     /transl_table=11
                     /translation="MPKPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRIDRHLV
                     NTRVTPNQLTYLMTVCGVLAAPALLVPGIAGAVLGVVAVQLYLLLDCVDGEIARWKKQY
                     SLAGVYLDRVGAYLTDAAVLVGFGMRAADIWGSGRIDWLWAFLGTLAALGAVLIKAETD
                     LVGVARHQGGLPPVKEAASELRSSGMALARRAASALQFHRLVLGIEASILILVLAVVDQ
                     IRGDLFFTRLGVAVLAAIALLQTLLHLVSVLASSRLK"
     gene            6886..7761
                     /locus_tag="RVR_RS30690"
                     /old_locus_tag="RVR_8532"
     CDS             6886..7761
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="RVR_RS30690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8532"
                     /product="glycosyltransferase"
                     /protein_id="WP_202239394.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-09,
                     bitscore: 36.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVGAVVITMGTRPAELQDLLDSVAKQQGAPVEVALVGNGSPLPV
                     MEREHLRTAELPENLGIPGGRNVGVELFGPGGRDVDVVLFLDDDGLLPGDDTAELVRRA
                     FEQDPELGIISFRIADPETGETQRRHVPRLRASDPMRNSRVTTFLGGASAVRTEVIRQV
                     GALPEQFFYAHEETDLAWRALDAGWMIDYRSDLVLLHPATSPARHAVYHRLVARNRVWL
                     ARRNLPWPLVPVYLGVWMALTLARRPSGTALRAWFGGFREGWATPCGPRRPMRWRTVWR
                     LTRLGRPPII"
     misc_feature    7830..7848
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            7842..8774
                     /locus_tag="RVR_RS30695"
                     /old_locus_tag="RVR_8535"
     CDS             7842..8774
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981489.1"
                     /locus_tag="RVR_RS30695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8535"
                     /product="ABC transporter permease"
                     /protein_id="WP_202237157.1"
                     /transl_table=11
                     /translation="MSDTTHNGAVAVGASPVPSAFDDGLSPAELAAKYGLSVSGARPGL
                     LTYTRLLWGRRHFINEFAKARTAAQYTQARLGQLWQVMTPLLNAAVYYLIFGILIGTHR
                     GIDNFIAFLVTGVFIFTFTQSSVLSGVKSISGNLGLIRALHFPRASMPIAFTLMQLQQL
                     MMSMFVLLAIVLMTGEVPDASWLLMFPALLCQWVFNTGLALIVARLGSKMTDLSQLMPF
                     MLRTWMYMSGVMYSITKLTTTAPHILRILLDVNPAAVYIDLMRFALIDSVTAAQMPAHV
                     WPMAVVWALVVGVGGYVYFWKAEESYGRG"
     gene            8761..9570
                     /locus_tag="RVR_RS30700"
                     /old_locus_tag="RVR_8537"
     CDS             8761..9570
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432678.1"
                     /locus_tag="RVR_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8537"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_202233427.1"
                     /transl_table=11
                     /translation="MAVAEQPALPPVQVSRPMVPTVIVEDVNIVYTVYGAGTGKGSASA
                     ALGRMLSKKRRSTNVRRVHAVKNVSFTAYRGEAIGIIGSNGSGKSTLLRAIAGLLPPES
                     GRIYTDGQPSLLGVNAALMNDLTGGTNVVLGGLAMGMSREEVRSRYKGIVDFSGINEKG
                     DFISLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRAFQRRSEERIRELRKEA
                     GTVFLVSHSNKSIRDTCERSIWLEHGVMLMDGPTEDVLAAYEAKTGK"
     misc_feature    9690..9699
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.21"
                     /tool="antismash"
     gene            10001..10888
                     /gene="hpnC"
                     /locus_tag="RVR_RS30705"
                     /old_locus_tag="RVR_8539"
     CDS             10001..10888
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019527751.1"
                     /locus_tag="RVR_RS30705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8539"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_202237158.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.5e-38, bitscore:
                     130.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5e-39,
                     bitscore: 133.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGDVASRAVLDKAARENFPVAPRILPRAWRQDLMAVYGFARLVD
                     DIGDGDLADGGRPDAVRLGLPAEAAGDRPTMLDAFEADLHRVFDGTPRHPLLLELRPTV
                     RKHRLTPEPFLGLIAANRQDQVVSRYATYGDLLAYCELSANPVGRLVLSITGTSTPERV
                     RRSDAVCTALQIVEHLQDVAEDLGRDRVYLPQEDMKLFSVDEADLAAPSAGEKVRELVA
                     FEAGRARDLLGEGGALVRSVRGRLRLLLAGFVGGGRAALRAVENAGYDVLSGSPKATKP
                     VLLREVGSTLRREG"
     gene            10885..11841
                     /gene="hpnD"
                     /locus_tag="RVR_RS30710"
                     /old_locus_tag="RVR_8540"
     CDS             10885..11841
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019993175.1"
                     /locus_tag="RVR_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8540"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_202237159.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.1e-53, bitscore:
                     181.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 6.9e-66,
                     bitscore: 221.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTVNGSAHTSGQVLAAYKYCETVTGHEARNFAYGIRLLPTAKR
                     QAMSAVYAFSRRVDDIGDGGLPPEEKLRRLEEARGLLHRVEAHEVEEDDTDPVAVALAD
                     SCAAFPIPLGGLGELIDGVQMDVRGESYETWDDLAVYCRCVAGAIGRVSLGVFGTVDGH
                     DHARAAEYADTLGLALQLTNILRDVREDAGNGRTYLPAQDLAKFGCAEGFHSDLPPAGS
                     DFTGLVEFEVRRARALFATGYRLLPMLDRRSGACVAAMAGIYRRLLERFAADPEAVLRG
                     RVSLPGREKAYVAVRGLAGLDARRTARTPVADPRRGV"
     gene            12071..13579
                     /gene="hpnE"
                     /locus_tag="RVR_RS30715"
                     /old_locus_tag="RVR_8541"
     CDS             12071..13579
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236661.1"
                     /locus_tag="RVR_RS30715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8541"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_202237160.1"
                     /transl_table=11
                     /translation="MTTTRSGPDAGPDTGPAGPGADPAARGRARRTAVVVGGGLAGVTA
                     ALALADAGVEVTLTEARPRLGGLAFSFKRGELTVDNGQHVFLRCCTAYQWFLDRIAARD
                     LVTLQDRLDVPVLDADTGRTGRIGRVGLPVPLHLAPSLLRYPHLSVAERASVGRAALAL
                     RGLDLDDPALDRVDFASWLAARGQSARTVEALWDLVAVATLNATSAQSSLGLAAKVFKT
                     GLLSAPGAADIGWAAVPLGDLHDGRARAALDAAGVRVLLRSRAAALTARPPGADDGSGG
                     DPARDVAHAGWCVNVETGPGRGEQLNAGTVVLAVPQHEAHELLPAGALEEPEKLLRIGT
                     APILNVHVIYDRQVLQQPFLAAIGSPVQWVFDRTRSSGLTGGGQYVALSQSAVQDEIDL
                     PVAELRRRYLPELERVLPAARGAAVRDFFVTRERTATFAPTPGVGALRPGPATRAPGLY
                     LAGAWTATGWPATMEGAVRSGLHASRQALSALGLPCEPGVLEAA"
     gene            13576..14655
                     /locus_tag="RVR_RS30720"
                     /old_locus_tag="RVR_8543"
     CDS             13576..14655
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308889.1"
                     /locus_tag="RVR_RS30720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8543"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_202237161.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.7e-59, bitscore:
                     197.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIGATRGENVTADSVIALLENGRILTTPVLRAAVARLAPPMDT
                     VASYHFGWIDEAGRPADGDGGKAVRPALALLSAQAAGAPAETGVPGAVAVELVHNFSLL
                     HDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEILLEQGTADAGRATRRLTTA
                     TRKLIDGQAQDISFEHRERVTVDECLEMEGNKTGALLACASSIGAVLGGASESDADALE
                     EYGYHLGLAFQAIDDLLGIWGDPATTGKQTWSDLRQRKKSLPVVAALAADGPAAERLGE
                     LLAADAKNSGLIETDAFSEEEFALRAALIEEAGGREWTSQEARRQYTTAIAALDKMDMP
                     EEIRRKLVGLADFVVVREK"
     gene            14755..16848
                     /gene="shc"
                     /locus_tag="RVR_RS30725"
                     /old_locus_tag="RVR_8546"
     CDS             14755..16848
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558138.1"
                     /locus_tag="RVR_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8546"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_202237162.1"
                     /sec_met_domain="T2TS (E-value: 6.5e-151, bitscore: 502.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGGPGTPTHRTPSASSASEPEPVPAGDTEAAAQRAVQRAA
                     DHLLARQHPDGWWKGDLETNVTMDAEDLLLREFLGIRDEQVTAASARWIRSQQREDGAW
                     PTFHGGPGDLSATIEAYVALRLAGDDPAEAHMALAAKWSRGEGGVAASRVFTRIWLALF
                     GWWDWDDLPEMPPEVIFLPKWMPLNIYSFGCWARQTIVPLTVVGAHRPVHPAPFGIDEL
                     HLDPGRPNPKQRRKSITSWDGVFQRLDQVLHAYRRFSPRMVRRSAMNACARWIIERQEA
                     DGCWGGIQPPAVYSVMALHLLGYDLDHPVVKAGLDSLDRFAVWPEDGVRMIEACQSPVW
                     DTCLATIALADAGIGADHPALVKAADWMLGEQITRPGDWSVQRPRLAPGGWAFEFHNDN
                     YPDVDDTAEVVLALRRIDHPDRARLDSAIDKAVRWNVGMQSRNGAWGAFDADNTSPFPN
                     RLPFCDFGEVIDPPSADVTAHVVEMLAALGLEHDGHTRRGIDWLLGEQEDSGAWFGRWG
                     VNYIYGTGSAVPALAAAGLGPDHPAIRRAVDWLHQVQNADGGWGEDLRSYSDQEWAGRG
                     HSTASQTAWALMALLAAGERDTASVERGVRWLTDTQLEDGSWDEPYFTGTGFPRDFSIN
                     YHLYRMVFPLTALGRYARAEPFGAGHPAAPSGGSAVTAPSTGASGSGMSSTSTTIPSTG
                     KGA"
     misc_feature    14798..14812
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            16852..17469
                     /locus_tag="RVR_RS30730"
                     /old_locus_tag="RVR_8547"
     CDS             16852..17469
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558139.1"
                     /locus_tag="RVR_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8547"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_202237163.1"
                     /transl_table=11
                     /translation="MGPSRPPLTVVCALPIERFALRRGTARNTADFPVTVLRTGMGPKN
                     AERVVAQALKDPALHGGSVLTTGFCAGLAPGMRPGDVVVSDDGHESARLAAALKAALAD
                     RGHTVHTGTLAESDHVVRGAERTALAATGAIAVDMESAAMRRAALAEGAHRIAAARVVV
                     DTPEFELVRVGTLRTGIIAFRVLRDLVPAFLDWHRTTTLPWR"
     gene            17475..18503
                     /gene="hpnH"
                     /locus_tag="RVR_RS30735"
                     /old_locus_tag="RVR_8549"
     CDS             17475..18503
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558140.1"
                     /locus_tag="RVR_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8549"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_202237164.1"
                     /sec_met_domain="PF04055 (E-value: 2.6e-17, bitscore: 62.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.2e-08, bitscore: 32.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTVRVASYLFEQKMVRRREKFPLIVELEPLFACNLKCEG
                     CGKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKFV
                     FLCTNALLMRKKMDKFTPSPYFAFTVHIDGMRERHDESVAKEGTFDEAVAAIKEAKRRG
                     FRVTTNSTFFNTDTPQTIIEVLNYLNDDLQVDEMMLSPAYAYEKAPDQEHFLGVEQTRE
                     LFRKAFGDGNRKKWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYV
                     PTYQKLLDETDWEKYGRGRDERCDNCMAHCGYEPTAVLATMGSLKESIRAARETVASNR
                     AK"
     gene            18631..>20493
                     /gene="dxs"
                     /locus_tag="RVR_RS30740"
                     /old_locus_tag="RVR_8551"
                     /pseudo=""
     CDS             18631..>20493
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552431.1"
                     /locus_tag="RVR_RS30740"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8551"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /pseudo=""
                     /sec_met_domain="DXP_synthase_N (E-value: 5.2e-111,
                     bitscore: 368.9, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.7e-06, bitscore:
                     24.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMLEHIKGPRDLKALPDGRLDELAADIRHFLVDAVARTGGHLGP
                     NLGVVELTIALHRVFDSPADRILWDTGHQSYVHKLLTGRQDFSKLRSKGGLSGYPSRAE
                     SEHDVIENSHASTVLGWADGLAKANEVRGSDDRVVAVIGDGALTGGMAWEALNNIAAAR
                     DRPLIIVVNDNERSYAPTIGGLANHLSTLRTTDGYERFLSWGKQLLQQTPVIGQPLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYLGPIDGHDIDAMESALRRARRFHGPVLVHCLTEK
                     GRGYAAAEQDEADHFHAVGAIDPATGRPLAPSAGPSWTSVFGEEMVAIGAERPDVVAIT
                     AAMLQPVGLAKFAAAYPHRVFDVGIAEQHAATSAAGLATGGLHPVVAVYATFLNRAFDQ
                     VLMDVALHRCGVTFVLDRAGVTGVDGASHNGMWDMSILQVVPGLRIAAPRDADQLRAQL
                     REAVAVDDAPTVVRFPKETAGEAVPALERVGGVDVLARPAGDLRPDVLLVSVGALAGTC
                     LSVAELLTGRGIGVTVADPRWVKPVDPALTELAAGHRMVAVVEDNGRVGGVGSTIAQAL
                     RDASVDVPLRDFGIPPQFLAHAKRGEVLADIGLVPAEIAGSVGAS"
     gene            20796..22232
                     /locus_tag="RVR_RS30745"
                     /old_locus_tag="RVR_8553"
     CDS             20796..22232
                     /NRPS_PKS="Domain: Aminotran_3 (58-380). E-value: 4e-87.
                     Score: 284.3. Matches aSDomain:
                     nrpspksdomains_RVR_RS30745_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552430.1"
                     /locus_tag="RVR_RS30745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8553"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_202237165.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.2e-86, bitscore:
                     288.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSDPTPEPGSPVPGGQPKGFDLGTLLAERGGERYDLHGKHLNH
                     QLPRMLHTIGFDKFYERAEGAHFWDAEGNDYLDMLAGFGVMGVGRHHPVVRKALHDVLD
                     AGLPDLTRFDCQPLPGLLAEKLLSYTPHLDRVFFGNSGTEAVETALKFARYATGKPRVL
                     YCKHSFHGLTTGSLSVNGEEGFQDGFAPLLPDTEIEVGDLDALARELKRGDVAAMIVEP
                     IQGHGVYIPPAGYLRSAQSLLRAHKALLICDEVQTGIGRTGTFYAYQQEEGVEPDLLTV
                     AKTLSGGYVPVGATLGRDWIFKKVYSSMDRVLVHSASYGSNAQAMVAGLATLSVMEDEQ
                     LVENSRRMGDLLRTRLAALVDEYELLKDVRGRGLMVAVEFGRPKSLKLRGRWTMLQAAR
                     KGLFAQMVVVPLLQRHRILTQVSGDHIEVIKLIPPLVVDEADIDRFVNAFTDVMDDAHG
                     GGGLMWDFGRTLVKQAVANR"
     aSDomain        20970..21935
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS30745_Aminotran_3.1"
                     /evalue="4.00E-87"
                     /label="RVR_RS30745_Aminotran_3.1"
                     /locus_tag="RVR_RS30745"
                     /protein_end="380"
                     /protein_start="58"
                     /score="284.3"
                     /tool="antismash"
                     /translation="FYERAEGAHFWDAEGNDYLDMLAGFGVMGVGRHHPVVRKALHDVL
                     DAGLPDLTRFDCQPLPGLLAEKLLSYTPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCKHSFHGLTTGSLSVNGEEGFQDGFAPLLPDTEIEVGDLDALARELKRGDVAAMIVE
                     PIQGHGVYIPPAGYLRSAQSLLRAHKALLICDEVQTGIGRTGTFYAYQQEEGVEPDLLT
                     VAKTLSGGYVPVGATLGRDWIFKKVYSSMDRVLVHSASYGSNAQAMVAGLATLSVMEDE
                     QLVENSRRMGDLLRTRLAALVDEYELLKDVRGRGLMVAVEF"
     gene            complement(22282..23142)
                     /locus_tag="RVR_RS30750"
                     /old_locus_tag="RVR_8555"
     CDS             complement(22282..23142)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267608.1"
                     /locus_tag="RVR_RS30750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8555"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_202237166.1"
                     /transl_table=11
                     /translation="MTQDVRQPATTGPEPRLTGVRNFRDVGGLPTADGRRVRPGVLFRS
                     GHLAHADEQDTDFLASLGLHTIFDFRNGDDIALEGPDVTLPGTRNINLPLSDPAQHAGF
                     WHTVRDGDLAALHAALGDGRGARRMEASYRKLVLERTSEHGRMLALLAGTAADQDPAGG
                     PAQGAAVPALLHCAAGKDRAGTSMAIILLALGVQRPAIEADYLESNARHRRYKVVRGDG
                     STGTAIDPEVRALLDPLFEARIEYLRAAFDTIDERWGSVDRYLEEGLCLGPAARTRLQD
                     HLLTG"
     gene            23456..24274
                     /locus_tag="RVR_RS30755"
                     /old_locus_tag="RVR_8556"
     CDS             23456..24274
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145655.1"
                     /locus_tag="RVR_RS30755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8556"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_202239396.1"
                     /transl_table=11
                     /translation="MLAPAAAGFGSYAAVGDSFTEGVGDPGPGEAFVGWADRLAGLLAG
                     RRAEGGPPGAFRYANLAVRGRLLDRIIDEQVPRAVTLAPDLVTFCAGGNDILRPGSDPD
                     ALAERFEGAVADLRAVVGTVLVCTGFDTRGVPVLGLLRGKIATYNAHIRAVADRYGCPV
                     LDLWSLRSIHDRRAWSEDRLHLSSAGHARVALRAAQVLGIETPSDPDLPWPPEPLRLPA
                     QVRKDNLHWAREYLVPWIGRRLRGESSGDDVLPKRPELLPLEPARLESCR"
     misc_feature    complement(23502..23514)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            complement(<24531..24761)
                     /locus_tag="RVR_RS38005"
                     /pseudo=""
     CDS             complement(<24531..24761)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="RVR_RS38005"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSASVADARARIRARLREWGADAELRDDAGLVVTELFTNAVRHTD
                     SRQITCALRDVGSAVRLEVTDQGCGGASPVPC"
     misc_feature    complement(24897..24911)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.91"
                     /tool="antismash"
     misc_feature    complement(24906..24920)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.89"
                     /tool="antismash"
     gene            25027..25851
                     /locus_tag="RVR_RS30765"
                     /old_locus_tag="RVR_8558"
     CDS             25027..25851
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571015.1"
                     /locus_tag="RVR_RS30765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8558"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_202239398.1"
                     /transl_table=11
                     /translation="MVLGKRLQDLREKAGLSFEQAGRALDVTHATIRRMEKAEVGLKIP
                     YVEKLLTTYGVTAPDEIGGFLALCREANRPGWWHNFRDVLPEWFSAFVSLEGEASVIRA
                     YEPHYVPGLLQVPSYAQAVLRAGLPNATSEEIDRLVTLRVERQALLSRAEAPLLWVVMD
                     ETVLRRPIGGPKVMREQVGALMDAADLPNVRLQVIPFAAGPHPAMYGPFHIFRFQLKEI
                     PDIAYTESLVGGAYFDDRDDVSTFLEALDRMCAQAAPAQSTKAILDGMRKEI"
     gene            25855..26106
                     /locus_tag="RVR_RS30770"
                     /old_locus_tag="RVR_8559"
     CDS             25855..26106
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175173.1"
                     /locus_tag="RVR_RS30770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_8559"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_202237167.1"
                     /transl_table=11
                     /translation="MDRVTNDSIYNGMPAAELGADGWRKPWSGGNGGSCVEAKRLNDGR
                     VALRQSTDPEGPALIYTNHEITSFIQGAKAGDADFLLG"
     misc_feature    26696..26709
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.22"
                     /tool="antismash"
ORIGIN
        1 gcggtcgggc cggagtgggt caggatcgcg gtggaggaca accaccccta ccggccgaag
       61 gcgctggagg ccgaccacgc gcgcaccggc gggcgcggcc tggtgctggt caagacgatc
      121 acggacgagg cgggcggctc ctgcgacatc gcgcagaccc cgggcggcgg gaaggtgatc
      181 tgggcggcgc tcccgctgcg cgcgcccctg tactgacggc ggggccggga cggcgaccgg
      241 gccgccgggc ggggaggacg accgggccgc cgggcgggga ggacggccgg gccggccggg
      301 ccggaggcgc gaagcgtgtc gccgcgcccc cggccccacc ggcccgcgcg gctcaccagc
      361 ccgcggtgcc ggccacctcg cgcacggcgg gcagcgccgc gtccagcacg gtctggaacc
      421 acgccgagaa cggaccgtcc tcacgcagct tcgccaactc cccgggcgtc acgaagagcg
      481 tctcgccgat ctcgtccggg tccggcagca gcggggcgcg aaccaccccg acgtacaggt
      541 ggttgtactc ctgctcgacc aggcccgagg cggggtccgg gtggttgtag cggaccgtgc
      601 cggcctcgcg catcagcgcc ggcgcgaccc ccagctcctc ggcggtgcgc cgggcggcgg
      661 ccacgaacgg ctgctcgccg gggtacgggt ggccgcagca ggtgttggac cacacgccgg
      721 gggagtggta cttgctcagc gccctgcgct ggagcagcag ccggccctcg tcgtcgaaga
      781 ggaagaccga gaacgcgcgg tgcagcctgc cgggcgcgag gtgcgccgac agcttctccg
      841 ccgtgccgat ggtgacgccg ttctcgtcga ccagttcgag catgatcggt tctgcgaccc
      901 cgtcggggga cggcacggtg gagggggagc cgggtcggcc ggtggcggga ctggtgggca
      961 tttccatcct tcgcgttcga cgacgagttc ttagtctgcc tcaccgccgc cgccgttccg
     1021 cgcgcgcacc gcccccgccg caccggcgtg aagagggcgc gaggtggtac ccgggggcgc
     1081 cccgcacccg tcagcggcac atgcccggct cgtgcgccgc gtggccggcc ggttcgagct
     1141 ggaaggtgca gtgcgccacg tcgaagtgcg tgccgaggca gccctggagg tcgtggagca
     1201 tcttctcgta ccccaccgcg tccagcacgt cctggctcac cacgacgtgc gcggacaaca
     1261 ccggcaggcc cgaggtgatg gtccacgcgt gcaggtcgtg cagcccctcg acgcccgcca
     1321 gcccctcgat gtggcggcgc acctgccgca tgtccacccc ccggggcgcc gcctccagca
     1381 gcacgtccag cgcctcgcgc atcagctgcc aggtgcgcgg cacgatcagt acgccgatca
     1441 gcagcgaggc gaccgcgtcg gcctgccgcc agcccgtgag caggtagacc acggccgccg
     1501 ccaccaccgc gagcgagccg aacgcgtcgg ccatcacctc caggaaggcg gcccgcacgt
     1561 tcaggctctc cttctggccg gccatcagca ccgccagcga caccgagttc gccaccaggc
     1621 cgatgacgcc gaagacgatc gtggcgccgc cgtcgatgcc gtgcggggtg atcaggcggc
     1681 ggacgccctc gtagaagatg aagacgccga cggcgagcag cagcagggcg ttgagcccgg
     1741 cggccaggat ctcggcgcgg gcgtagccga aggtgcggcg ctcgctcggc ggccgggccg
     1801 cgacgtggac ggccagcagc gccatcgcca ggcccgccgc gtcggtggcc atgtggcccg
     1861 cgtcggccag cagggcgagc gagccggtga ccaggctccc ggccacctcg gtggccagca
     1921 ccagcagggt gatcgtcagg gcgatccgca gccggccgcg gtgcgcgccg ccggcggtgg
     1981 tggccgtgcc gtgctggtgg ccatggctgt ggccgtgtcc gtgtccgtgg tggtgaccgc
     2041 tccctgcccc catcgacggg gcccccttcc gcatgcgcct gggtgtccgc tgaacgcctg
     2101 ctctcgtggt ccgcgggcca gtcaacaccg gttacccacc gtgggcaagc cgatactgga
     2161 gaccgttgtc atgtgcggtg acctggggtg gtgaggtgac cctaatccgt cgccgaaggg
     2221 ggggcgcgga ggtgccggag ggcccgctcg ccccgatgtt gtggcgggcg accggaatcg
     2281 aggatgatga tcacactggg cgggccacgt tcaggcgaac acgcagtgaa cgactgccga
     2341 cccgcatccg ataacctcgc cgtcgtgtcc ggcccggagc cgcctgccgc ggcctcgccg
     2401 gtgcgccttc gtacgcattc agggagtggg ttcctctgtc gaccgcaatt ctcaccggcc
     2461 cgcccgacgc cgggacgccg tcgccgctcg cggacgacct gcgggctctg ggattccagg
     2521 tcgtggaggc cgacgggccg cgcgcggtgg ccgagcgcgt cgccggcgcg ccgcccgccg
     2581 agcgcgtcgc ggtcgtcgac cgccgcttcc gcggccaccg ccacgccctg cggctggccc
     2641 tgaccgaccc ccgcttcgac gccggcgccg tgcccggcgc gctggccgtg caggccgccg
     2701 cccggcccgc gctgtcccgg gcgctccacg agctggccgg cggcgcggac gccgccgccc
     2761 cggccgccgg cggcccggcc gcgccccagg gcggcgcgcc caccgccacg gtcgccgacg
     2821 gcgacgtcct cgccgacgtg ctggccgggg aactgggccg gcagggcgcc gagccgtacc
     2881 ggcccgaact gggcgtcctg gtggcccggg tggcccgcgg gccccaggag gaggccgccg
     2941 cggccgaggc ggtcgccggc gtggacgagg aggcggtgcg gctgcgcagc gcggtgaagt
     3001 cccgcgacgg gttcttcacc acgcactgca tcagcccgta ctcccgctac atcgcgcgct
     3061 ggtgcgcccg gcgcggcctg acccccaacc aggtgaccac cgcctccctg ctggtcgcgc
     3121 tgatcgccgc cgggtgcgcg gcgaccggca cccgcggcgg gtacgtcgcc gccggcgtgc
     3181 tgctgctcgc ctcgttcgtc ctggactgca ccgacggcca gctcgcccgc tactccctcc
     3241 agtactccac cctcggcgcc tggctcgacg cgaccttcga ccgcgccaag gagtacgcct
     3301 actacgccgg cctggcgctg ggcgccgccc gcggcggcca cgacgacgtg tgggcgctgg
     3361 ccctgggcgc gatggtgctc cagacctgcc gccacgtcgt ggacttcgcc ttcaacgagg
     3421 ccaaccacga cgccgccgcc aacaccagcc ccaccgccgc cctgtccggg cggctggaca
     3481 gcgtcggctg gacggtgtgg gtgcgccgga tgatcgtgct gccgatcggc gagcgctggt
     3541 tcctgatcgc ggtcctcacc gccgccacca ccccccgcgt caccttcgtg gtgctgctca
     3601 tcggctgcgc gctggccgcc tgctacacca ccgccggccg cgtgctgcgc tccctcaccc
     3661 gcaaggcccg gcggacggac cgggccgcgc aggcgctcgc cgacctcgcc gacagcggcc
     3721 cgctggccga ggccgtggcg cgcgtcgcgg cgccgctcgc ccggcggctg cccgccttcg
     3781 cccccccgct gctcgccgcg atcggcgccg gagcgctcac cgcgaccgcc gcgctggcca
     3841 cccgcggcac ctggtgggtc gtggcggccg ccgtgctcta cgtcgtgacc agcgcgatcg
     3901 ccgtcgcccg cccgctgaag ggcgcactgg actggctggt gccgccgttc ttccgggccg
     3961 gcgagtacgg cgcggtgctg gcactggccg ccgtctccga ggtgaacgga gcgttgcccg
     4021 ccgccttcgg gctggtggcc gcggtcgcct accatcacta cgacacggtc taccgcatcc
     4081 gcggcggaac cggagccccg ccccgcgcac tggtgcgggc ggccggcggc cacgagggcc
     4141 gggcgctgct ggtggccgtg ctgtcggcgg tcctggtcac cggaagccgc cacgacggct
     4201 tcaccgccgc actgacggtg ctcgccgccg tcctcgcgct gctcgtcctc accgagagca
     4261 tccgcttctg ggtgtcctcg ggggcacccg ccgtacacga cgagtcagga gaacccgcat
     4321 gatcggcctg gtgctggcgg caggcgcagg acggcgcctg cggccgtaca cggacacgct
     4381 gccgaaggcg ctggtgccgg tcgggccgga cggcgcggcg gacggcccga cggtgctcga
     4441 cctcacgctc ggcaacttcg cggcggtcgg catcacccgt gccgcggtcg tcgtcggcta
     4501 ccgcaaggag gccgtctacg cccgcaagga ggcgctggag gcccgctacg gcgtcgagct
     4561 gaccctcgtc gacaacgaca aggccgagga gtggaacaac gcctactccc tgtggtgcgc
     4621 gcgcgacgtg ctgcgggagg gagtgattct ggccaacggc gacaccgtcc acccggtctc
     4681 cgtcgagcgc acgctgctgg ccgcccgcgg tgacggccgc cggatcatcc tcgcgctgga
     4741 cacggccaag aagctcgccg acgaggagat gaaggtcgtc gccgagcccg gccgtggggt
     4801 gcgccggatc accaagctga tggacccggc cgaggccacc ggggagtaca tcggcgtcac
     4861 cctgatcgag gcggacgccg cggccgacct cgccgacgcg ctcaaggcca cctacgagcg
     4921 cgaccccgac ctgtactacg aggacggcta ccaggaactg gtcgaccgcg gccacgtgct
     4981 ggacgtggca ccggtcggcg acatcccctg ggtcgagatc gacaaccacg ccgacctcgc
     5041 ccgcggacgg gagatcgcgt gccagtactg acccggctga tcccctcgcc ggtcgtcgtc
     5101 gacatccgcg ggggcgcgct cgccgacctc tcccggctgc tggccgacga gcggatctcg
     5161 acgtccggca agatcgccgt ggcggtcagc gacggctccg gcgcccggct gcgcgagcgg
     5221 ctggcgcccg aactgccggg cgccgactgg ttcccggtcg ccgccggcac catcgacgcc
     5281 gccgtgaagc tcgccgacgc catgcgcggc cagcgctacg acgcggtggt cgcgctgggc
     5341 ggcgggaaga tcatcgacgc cgcgaagtac gcggccgccc gggtcgggct gccgatggtg
     5401 gcggtcgcca ccaacctctc gcacgacggc atctgctcgc cgatctccac cctcgacaac
     5461 gacaacgggc gcggctcgta cggcgtgccc ggcccgatcg cggtcgtgat cgacctggac
     5521 gtcatccgcg aggccccgag ccgctacctg cgggccggca tcggcgacgc ggtctccaac
     5581 ctctccgcgc tcgccgactg ggagctgtcc caccgcgaga ccggcgagcg gatcgacggc
     5641 ctggccgcgg ccatggcgcg cggcgcgggc gaggcggtgc tgcggcaccc gggcaccgtc
     5701 gccgacgacg acttcctcgt catcctcgcc gagggcctgg tgctcaccgg catcgcgatg
     5761 tcgatcagcg gggacagccg cccctcctcg ggcgcctgcc acgagatcag ccacgccttc
     5821 gacctgctcc acccgcaacg ggccgccgcg cacggcgagc aggtgggcat cggcgcggcc
     5881 ttcgcgatgc acctgcgcgg cgcccgcgag gagtccgcgc tcatcgccga cacgctgcgg
     5941 cggcacggac tgccggtgct gccggagcag atcggcttct ccgcccagga gttcgtggag
     6001 gcggtgcgct acgcgccgca gacccggccc gggcgccaca cgattctgga acacctcgac
     6061 ctgtccgcca ccgagatcag ggacgcgtac gccgactatg ccaaaaccat cagtagctga
     6121 gctgcgcccc gtcgttcatc cggcgggcgt caaggaccgg cgcagcgggg agcactgggc
     6181 cggccggctg tacatgcgcg aggtgtcgct gcgcatcgac cgccacctgg tgaacacccg
     6241 cgtcacgccc aaccagctga cctacctgat gaccgtctgc ggcgtgctcg ccgcaccggc
     6301 cctgctggtc cccggcatag ccggcgccgt gctcggcgtg gtcgcggtcc agctctacct
     6361 gctgctggac tgcgtcgacg gcgagatcgc ccgctggaag aagcagtact cgctggccgg
     6421 cgtgtacctc gaccgcgtcg gcgcctacct gaccgacgcg gccgtgctgg tcggcttcgg
     6481 catgcgcgcc gccgacatct ggggcagcgg ccgcatcgac tggctgtggg cgttcctcgg
     6541 caccctggcc gcgctcggcg ccgtgctgat caaggcggag accgacctgg tcggcgtggc
     6601 ccggcaccag ggcgggctgc cgccggtcaa ggaggcggcc tccgagctgc gctcctccgg
     6661 gatggcgctg gcccgccggg ccgcctccgc gctccagttc caccggctgg tgctcggcat
     6721 cgaggcgtcg atcctcatcc tggtgctcgc cgtcgtcgac cagatccgcg gcgacctgtt
     6781 cttcacccgc ctcggcgtgg ccgtgctggc cgcgatcgcg ctgctccaga ccctcctgca
     6841 cctcgtctcc gtcctcgcgt cgagcaggct gaagtgagcg ccccgctgac ggtgggtgcc
     6901 gtcgtcatca ccatgggcac ccgacccgcg gagctccagg acctgctgga ctccgtcgcc
     6961 aagcagcagg gcgccccggt cgaggtggcg ctcgtcggca acggctcgcc gctgccggtg
     7021 atggagcgcg agcacctgcg caccgccgaa ctgccggaga acctgggcat ccccggcggc
     7081 cgcaacgtcg gggtggagct gttcggcccc ggcggccggg acgtcgacgt cgtcctcttc
     7141 ctcgacgacg acggcctgct gcccggcgac gacaccgccg agctggtccg ccgggccttc
     7201 gagcaggacc cggagctggg catcatcagc ttccggatcg ccgacccgga gaccggcgag
     7261 acccagcgcc ggcacgtgcc gcggctgcgt gcctcggacc cgatgcgcaa ctcgcgggtg
     7321 accaccttcc tcggcggtgc cagcgcggtg cgcaccgagg tcatccggca ggtcggcgcc
     7381 ctgcccgagc agttcttcta cgcccatgag gagacggatc tggcctggcg tgcccttgac
     7441 gccggctgga tgatcgacta ccgctccgac ctggtgctgc tccacccggc cacctcgccg
     7501 gcccggcacg cggtctacca ccggctggtg gccaggaacc gggtctggct ggcccggcgc
     7561 aacctgccct ggcccctggt gccggtgtac ctcggcgtat ggatggcgct caccttggcg
     7621 cgcaggccct cgggcaccgc gctgcgcgcg tggttcggcg gcttccggga gggctgggcc
     7681 accccgtgcg gcccgcgccg cccgatgcgc tggcgtacgg tgtggcggtt gacccggctg
     7741 ggccgacccc cgatcatctg acaagctcgg atctgagagc atcaggcgca gtccgggaac
     7801 ccctgcaccc ggcgcgcacc ttgaggacga aagtgtcaac tgtgagcgat acgacgcaca
     7861 acggtgcggt cgccgtcggc gcctcgccag tgccctcggc cttcgacgac ggcctcagcc
     7921 ccgccgaact cgccgccaag tacgggttgt cggtcagtgg tgcgcggccc gggttgttga
     7981 cctacacgcg tctgttgtgg ggtcgtcgac atttcatcaa cgagttcgcg aaggcgcgga
     8041 cggcggcgca gtacacgcag gcgcggctgg gtcagttgtg gcaggtgatg acgccgttgt
     8101 tgaacgcggc ggtgtactac ctgatcttcg ggatcctgat cggtacgcat cgggggatcg
     8161 acaacttcat cgcgttcctg gtgacgggtg tgttcatctt cacgttcacg cagtcgtcgg
     8221 tgttgagcgg ggtgaagtcg atctcgggga atctggggtt gatccgggcg ttgcattttc
     8281 cgcgggcgtc gatgccgatc gcgttcacgt tgatgcagtt gcagcagttg atgatgtcga
     8341 tgttcgtgtt gctggcgatc gtgttgatga ccggtgaggt gccggacgcg tcgtggttgt
     8401 tgatgttccc ggcgttgttg tgccagtggg tgttcaacac ggggttggcg ttgatcgtgg
     8461 cgcggttggg cagcaagatg acggatctgt cgcagttgat gccgttcatg ttgcggacgt
     8521 ggatgtacat gtcgggggtg atgtacagca tcacgaagtt gacgacgacg gcgccgcaca
     8581 tcctgcggat cctgttggat gtgaatccgg cggcggtgta catcgatctg atgcggttcg
     8641 cgttgatcga ttcggtgacg gcggcgcaga tgccggcgca tgtgtggccg atggcggtgg
     8701 tgtgggcgct ggtcgtcggt gtcggtgggt acgtgtactt ctggaaggcg gaagagtcct
     8761 atggccgtgg ctgagcagcc ggcgcttccg ccggtgcagg tgagtcgtcc gatggtgccg
     8821 acggtgatcg tggaggacgt gaacatcgtc tacacggtgt acggggcggg gacgggtaag
     8881 gggagtgcgt cggcggcgtt gggtcggatg ctgtcgaaga agcgccggtc gacgaacgtg
     8941 cggcgggtgc atgcggtgaa gaacgtgagt ttcacggcgt atcggggtga ggcgatcggg
     9001 atcatcgggt cgaacggttc ggggaagtcg acgttgttgc gggcgattgc ggggttgctg
     9061 ccgccggagt cggggcggat ctacacggat gggcagccgt cgttgctggg ggtgaacgcg
     9121 gcgttgatga atgatctgac gggggggacg aacgtggtcc tgggggggtt ggcgatgggg
     9181 atgtcgcggg aggaggtgcg gtcgcggtac aaggggatcg tggatttctc ggggatcaac
     9241 gagaagggtg atttcatctc gttgccgatg cggacgtatt cgtcgggtat ggcggcgcgg
     9301 ttgcggttct cgatcgcggc ggcgaaggat catgacgtgt tgatgatcga tgaggcgttg
     9361 gcgacgggtg accgggcgtt ccagcggcgg tcggaggagc ggatccggga gttgcggaag
     9421 gaggcgggga cggtgttcct ggtcagtcac agcaacaagt cgatccggga cacgtgtgag
     9481 cggtcgatct ggttggagca cggggtgatg ctgatggacg ggccgaccga ggacgtcctc
     9541 gccgcctacg aggcgaagac cggcaagtga ggatccggcg gcgggcgggc ggcggctgac
     9601 gtggcgtcgg gaaccggccg caccgacccc gcggccgcac cttgtccggc ttcgtccggc
     9661 tcggtccgcc gtgccgaccg gatccgggaa gttttttgcc ggaacatgat ccccgccgga
     9721 tgatccggcg gggatcggtt gttgaggtcg ggtgtcgccg cccgccgatc gggggcgcgc
     9781 ccccggcgta cgccgggtaa gcctccgacg taagctgtac cggtgctggg agcctgccga
     9841 tgatcgatac ccgggtacgg gtgaccgcga gtgagcatgc ggcgtgtccg aaatgggaag
     9901 tttcgacggg gcagtgtaga acgggggatg tggcggccat gaagatcggg accatcctgc
     9961 tccggggcgc gctcgccgcc tgtgcgccgg gaagcccgcg gtgaccgggg acgtcgcctc
    10021 ccgtgccgtc ctcgacaagg ccgcgcgcga gaacttcccc gtggcaccga ggatccttcc
    10081 gcgcgcctgg cgccaggacc tgatggccgt ctacggattc gcccgtctgg tggacgacat
    10141 cggcgacggc gacctggccg acggcggccg gcccgacgcg gtccggctcg gcctgcccgc
    10201 cgaggcggcc ggcgaccgcc cgacgatgct cgacgccttc gaggccgacc tgcaccgggt
    10261 gttcgacggc accccccggc acccgctgct gctggagctg cgcccgaccg tgcgcaagca
    10321 ccggctgacc cccgagccct tcctcggcct catcgccgcc aaccgccagg accaggtggt
    10381 cagccgctac gccacctacg gcgacctgct cgcctactgc gagctgtccg ccaatccggt
    10441 gggccggctg gtgctctcca tcaccggcac ctccaccccg gagcgggtcc ggcgctccga
    10501 cgcggtgtgc accgcgttgc agatcgtgga gcacctccag gacgtcgcgg aggatctcgg
    10561 cagggaccgg gtgtacctcc cccaggagga catgaaactc ttctcggtgg acgaggccga
    10621 cctcgccgcg ccgagcgcgg gggagaaggt acgcgagctg gtcgcgttcg aagccgggcg
    10681 ggcccgtgac ctgctgggcg agggcggtgc cctggtccgc agcgtgcggg gccggctcag
    10741 actgctgctg gccggattcg tcggcggcgg tcgtgcggcg ttgcgggcgg tggagaacgc
    10801 ggggtacgac gtgctgtcgg gttcacccaa ggccaccaag cccgtcctgc tgcgtgaggt
    10861 ggggtcgaca ttgcgaagag aggggtgacc cggaccgtga acggttcagc gcacacgtcc
    10921 ggacaggtgc ttgctgcata caagtactgt gagaccgtga ccggccacga ggcccgcaac
    10981 ttcgcctacg gaatccgtct gctgcccacg gcgaagcggc aggcgatgtc ggcggtctac
    11041 gccttctccc ggcgggtcga cgacatcggg gacggcgggc tgccgcccga ggagaagctg
    11101 cgccggctgg aggaggcccg cgggctgctg caccgcgtcg aggcccacga ggtcgaggag
    11161 gacgacaccg acccggtggc ggtcgccctc gccgactcct gcgcggcctt cccgatcccg
    11221 ctgggcggtc tcggcgaact catcgacggc gtccagatgg acgtgcgggg cgagagctac
    11281 gagacctggg acgacctggc cgtttactgc cgctgtgtgg cgggagctat cggtagggtc
    11341 tcattgggcg ttttcggcac cgtggatggg cacgatcacg ctcgtgccgc cgaatacgcc
    11401 gacacgctcg gcctcgccct gcagctcacc aacatcctgc gcgacgtccg cgaggatgcc
    11461 ggcaacggac gcacctacct gcctgcccag gacctcgcca agttcggctg cgccgagggc
    11521 ttccacagcg acctgccgcc ggccggctcc gacttcaccg gcctggtcga gttcgaagtg
    11581 cgccgggccc gcgcgctgtt cgccaccggc taccggctgc tgccgatgct cgaccgcagg
    11641 agcggcgcct gtgtcgccgc catggccggc atctaccggc ggctgctgga gcggttcgcc
    11701 gccgaccccg aggcggtgct gcgcggtcgg gtgtccctgc ctggccggga gaaggcgtac
    11761 gtcgccgtcc gcggcctcgc cggcctcgac gcccgccgca ccgcgcgtac ccccgtcgcc
    11821 gatccgcgga ggggcgtgtg agaacgaccc gcgtgcacca agcgggttcc accgcgcagt
    11881 ccgcccccgg cacgtccccc gccacgccgc tcgcccggcc cgtccgttcc gcccggtccc
    11941 tccggcgggc gcggttcccg cggccgctcg cgcacccgtc gtccggccga gcaaccctgc
    12001 cgacgcgccc tgcgtcacct tccgcgacgg cccgccgcac cccgctcggt gcggcccgag
    12061 gagagcacgc atgacgacca cccgatccgg cccggacgcc ggtccggaca ccggcccggc
    12121 cgggccggga gccgaccccg ccgcgcgcgg ccgcgcgcgg cgcaccgccg tcgtggtcgg
    12181 cggcggcctg gccggggtga ccgcggcgct cgcgctcgcc gacgccgggg tcgaggtgac
    12241 cttgaccgag gcccggccgc ggctgggcgg cctcgccttc tccttcaagc gcggcgagtt
    12301 gaccgtggac aacggccagc acgtcttcct gcgctgctgc accgcctacc agtggttcct
    12361 ggaccggatc gcggcccgcg acctggtgac cctccaggac cggctggacg tgccggtcct
    12421 ggacgcggac accggcagga ccggacggat cggccgggtg gggctgccgg tcccgctgca
    12481 cctggccccg agcctgctgc gctacccgca cctgtcggtg gccgagcggg cgtcggtcgg
    12541 gcgcgccgcg ctcgcgctgc gcggcctgga cctggacgac ccggccctgg accgggtcga
    12601 cttcgcctcc tggctcgccg cgcgcgggca gtccgcgcgg accgtcgagg cgctgtggga
    12661 cctggtggcg gtggccactt tgaacgcgac ctcggcccag tcctcgctgg gcctggccgc
    12721 gaaggtgttc aagaccgggc tgctgtccgc gccgggcgcc gccgacatcg gctgggcggc
    12781 ggtcccgctc ggcgacctgc acgacggccg ggcccgcgcg gcgctggacg cggccggggt
    12841 gcgggtactc ctgcggtccc gcgcggccgc cctgacggcc cgtccgccgg gcgcggacga
    12901 cggctccggc ggcgacccgg cacgtgacgt cgcccacgcc gggtggtgcg tgaacgtgga
    12961 gaccgggccc ggccgcggcg agcaactcaa cgccggcacg gtggtgttgg cggtgccgca
    13021 gcacgaggcg cacgaactgc tgccggcggg tgcgctggag gagccggaaa agctcttgcg
    13081 gatcgggacg gcgccgatcc tcaatgtcca tgtgatctac gaccggcagg tgctccagca
    13141 gccgttcctg gcggcgatcg gcagtccggt ccagtgggtc ttcgaccgca ccaggagctc
    13201 cgggctcacc ggcggcggcc agtacgtggc gctgtcccag tccgccgtgc aggacgagat
    13261 cgacctgccg gtggccgagt tgcgccgacg ctacctgccg gagctggagc gggtgctgcc
    13321 cgccgcccgc ggcgcggccg tccgcgactt cttcgtcacc cgtgaacgca ccgcgacctt
    13381 cgcgcccacg ccgggcgtgg gagccctgcg ccccgggccc gccacccgtg cccccggcct
    13441 gtacctggcc ggcgcgtgga ccgccaccgg ctggcccgcg accatggagg gtgcggtgcg
    13501 cagcggcctg cacgcctccc gacaagcttt gtccgccctc ggactgccct gtgaacccgg
    13561 cgtactggag gcggcatgag tgcaattggt gcgacaagag gagagaacgt gaccgctgac
    13621 agcgtgatcg cgctgctgga gaacggccgc atcctgacca cccccgtgct ccgcgcggcc
    13681 gtcgcacggc tcgccccgcc gatggacacc gtcgcctcgt accacttcgg gtggatcgac
    13741 gaggccggcc ggcccgcgga cggggacggc ggcaaggcgg tgcgtcccgc gctggccctg
    13801 ctgtccgcgc aggccgcggg cgcgcccgcg gagaccggcg tgcccggcgc ggtcgcggtg
    13861 gagctggtgc acaacttctc gctgctgcac gacgacctga tggacggcga cgagcagcgc
    13921 cggcaccggg acacggtgtg gaaggtgcac ggaccggccc aggcgatcct ggtcggcgac
    13981 gcgctcttcg cgctggccaa cgagatcctg ctggagcagg gcaccgccga cgccggccgg
    14041 gccacccgcc ggctgaccac cgcgacccgc aagctgatcg acggtcaggc ccaggacatc
    14101 tccttcgagc accgcgagcg ggtcaccgtg gacgagtgcc tggagatgga gggcaacaag
    14161 accggcgccc tgctggcctg cgcctcctcc atcggcgcgg tgctcggcgg agcctcggag
    14221 tccgacgcgg acgcgctgga ggagtacggc taccacctgg ggctcgcgtt ccaggcgatc
    14281 gacgacctgc tcggcatctg gggcgacccg gccaccaccg gcaagcagac ctggagcgac
    14341 ctgcggcagc gcaagaagtc gctgccggtg gtcgcggcgc tcgccgccga cggccccgcg
    14401 gccgagcggc tgggcgaact cctggcggcg gacgcgaaaa actccggact gatcgaaact
    14461 gatgccttca gcgaggaaga gttcgccctg cgggcggcgt tgatcgagga ggcaggtggt
    14521 cgggagtgga cgtcccagga ggcccggaga cagtacacga ccgccattgc cgcactggac
    14581 aaaatggaca tgccggaaga aatccgacgt aagctcgtgg gcctggcgga ttttgtggtg
    14641 gtccgcgaga agtaaacaga cagacgtgga gcgtatgacg tcgccggtct cactcttgtg
    14701 acggcggacg gccgcccccg acaccgcaga agtctcaact gcaaagggga agccatgaca
    14761 gcgacgaccg acggcggtcc agggacgcca acccaccgga caccttcggc cagtagcgcc
    14821 tcggagccgg agcctgttcc agccggtgac acagaggcgg cggcgcagcg tgccgtgcag
    14881 cgcgccgcag accacctcct ggcacggcag caccctgacg gatggtggaa aggcgacctc
    14941 gagacaaacg tgacgatgga tgccgaggac ctgctgctgc gggagttcct cggcatccgt
    15001 gacgagcagg tcaccgcggc ctcggcccgc tggatccgct cgcagcagcg cgaggacggc
    15061 gcctggccca ccttccacgg cgggcccggc gacctctcgg cgaccatcga ggcgtacgtc
    15121 gccctgcggt tggccgggga cgacccggcc gaggcgcaca tggcgctggc cgcgaagtgg
    15181 tcccgcggcg aggggggcgt ggccgccagc cgggtcttca cccggatctg gctcgccctg
    15241 ttcggctggt gggactggga cgacctgccg gagatgccgc ccgaggtcat cttcctgccc
    15301 aagtggatgc cgctgaacat ctactcgttc ggctgctggg cccggcagac catcgtgccg
    15361 ctgaccgtgg tcggcgccca ccggccggtg caccccgcgc cgttcggcat cgacgaactg
    15421 cacctcgacc cgggccggcc gaaccccaag cagcgccgca agtcgatcac cagttgggac
    15481 ggcgtcttcc agcgcctgga ccaggtgctg cacgcctacc gcaggttcag cccccggatg
    15541 gtgcgccgca gcgcgatgaa cgcgtgcgcc cgctggatca tcgagcgcca ggaggccgac
    15601 ggctgctggg gcggcatcca accgcccgcg gtctactcgg tgatggccct gcacctgctc
    15661 gggtacgacc tggaccaccc ggtggtcaag gccggactgg actcgctgga tcgtttcgcc
    15721 gtgtggcccg aggacggcgt gcggatgatc gaggcgtgcc agtccccggt ctgggacacc
    15781 tgcctggcga ccatcgcgct cgccgacgcc ggcatcggcg ccgaccaccc ggcgctggtc
    15841 aaggccgcgg actggatgct cggcgagcag atcacccgcc ccggcgactg gtccgtgcag
    15901 cgcccccgac tggcgcccgg cggctgggcc ttcgagttcc acaacgacaa ctacccggac
    15961 gtggacgaca cggccgaggt ggtgctcgcg ctgcgccgga tcgaccaccc cgaccgggcc
    16021 cggctcgact ccgcgatcga caaggcggtg cgctggaacg tcggcatgca gtccaggaac
    16081 ggcgcctggg gcgccttcga cgccgacaac accagcccct tcccgaaccg gttgccgttc
    16141 tgcgacttcg gcgaggtgat cgacccgccg tcggccgacg tgaccgcaca cgtggtggag
    16201 atgctggccg ccctcggcct ggagcacgac gggcacaccc ggcgcggcat cgactggctg
    16261 ctgggggaac aggaggacag cggcgcctgg ttcggccgct ggggggtcaa ctacatctac
    16321 ggcaccgggt cggccgtccc ggcgctggcc gcggcggggc tcggcccgga ccacccggcg
    16381 atccgccggg ccgtcgactg gctccaccag gtgcagaacg ccgacggcgg ctggggcgag
    16441 gacctccggt cctacagcga ccaggagtgg gccggccgcg ggcactcgac cgcgtcgcag
    16501 accgcgtggg cgctgatggc gctgctggcg gccggcgaac gggacaccgc gtccgtcgag
    16561 cgcggggtgc gctggctgac cgacacccag ctcgaggacg gctcgtggga cgagccgtac
    16621 ttcaccggca ccggcttccc gcgcgacttc tcgatcaact accacctgta ccggatggtc
    16681 ttcccgctga ccgcgctcgg ccgctacgcc cgcgccgagc ccttcggcgc cggccacccg
    16741 gcggccccgt ccggcgggtc cgccgtgacc gcgccgagca ccggcgcgtc cggttccggc
    16801 atgtccagca cgtccaccac catcccgagc accggaaagg gggcctagtt cgtgggccct
    16861 tcccgacccc cgctgacggt ggtctgcgcc ctgccgatcg agcgcttcgc gctgcgcagg
    16921 ggcaccgcca ggaacaccgc ggacttcccg gtcaccgtgc tgcgaaccgg catgggaccg
    16981 aagaacgcgg agcgggtcgt cgcccaggcc ctgaaggacc cggcgctgca cggaggttcc
    17041 gtcctgacca ccggcttctg cgcggggctc gcccccggca tgcggccggg agacgtcgtc
    17101 gtctccgacg acgggcacga gagcgcgcgg cttgccgccg cgctcaaggc cgctctcgcg
    17161 gaccggggcc acaccgtgca caccggcacg ttggcggagt ccgatcatgt cgtgcggggc
    17221 gccgagcgca ccgcactcgc ggcgacgggt gccatcgccg tggacatgga gtcggccgcg
    17281 atgcgccgtg ccgctctcgc cgagggcgcg caccgcatcg cggcggcccg cgtcgtcgtc
    17341 gacacgcccg agttcgaact cgtccgtgtc ggaacgcttc gcaccgggat catcgcattc
    17401 cgcgtgctca gagatcttgt tcccgccttt ctcgattggc accgcactac cacgctcccc
    17461 tggaggtgag ccagatggcc atgccgctcc gtcagaccgt ccgcgtcgcg tcgtacctct
    17521 tcgaacagaa aatggtccgg cgtcgcgaaa agttcccgct gatcgtcgaa ctcgaaccgc
    17581 tcttcgcctg caacctcaaa tgtgagggct gcggcaagat ccagcacccg gccggggtgc
    17641 tgaagcagcg catgccggtt gcccaggcgg tcggggcggt gctggagtcg ggtgcgccga
    17701 tggtctccat cgcgggcggc gagccgctca tgcaccccca gatcgacgag atcgtgcgcc
    17761 agctcgtcgc tcgtaagaaa ttcgtattcc tctgcacgaa cgccctgctc atgcgcaaga
    17821 agatggacaa gttcacacct tctccttact ttgcttttac cgtgcacatt gacggtatgc
    17881 gggagcggca cgacgagtcg gtggccaagg agggcacctt cgacgaggcg gtggcggcga
    17941 tcaaggaggc caagcgccgc ggcttccggg tgaccaccaa ctccaccttc ttcaacaccg
    18001 acaccccgca gacgatcatc gaggtgctca actacctcaa cgacgacctc caggtcgacg
    18061 agatgatgct gtcgcccgcg tacgcgtacg agaaggcccc cgaccaggag cacttcctcg
    18121 gtgtcgagca gacccgcgag ctgttccgca aggcgttcgg cgacggcaac cgcaagaagt
    18181 ggcggctcaa ccacagcccg ctcttcctgg acttcctgga gggcaaggcg gacttcccct
    18241 gcaccgcctg ggcgatcccc aactactctc tcttcggctg gcagcgcccc tgctacctga
    18301 tgagcgacgg ctacgtgccg acgtaccaga agctcctgga cgagaccgac tgggagaagt
    18361 acggccgcgg gcgggacgag cggtgcgaca actgcatggc gcactgcggc tacgagccca
    18421 cggccgtgct ggccaccatg ggctcgctga aggagtccat ccgcgccgcc cgggagaccg
    18481 tcgcgtccaa ccgcgcgaag tgaccgcccg gtaaaagcgg gtacgagcca ccggtacggc
    18541 atccgccgcc ggtggctcgt actccgcgct gccaccggcc ggtcagcggc cggcgatcca
    18601 ccgcaatccc ggcaggaacg aggtccacgc atgtcgatgc tggagcacat caaaggcccg
    18661 cgcgacctga aggcactgcc cgacggccgg ctcgacgaac tcgcggccga catccgccac
    18721 ttcctcgtcg acgcggtcgc caggacaggc ggccacctcg gcccgaacct cggcgtggtg
    18781 gagctgacga tcgcgctgca ccgcgtcttc gactcacccg ccgaccgcat cctgtgggac
    18841 accggccacc agtcctacgt gcacaagctg ctcaccggac gccaggactt ctccaagctc
    18901 cgcagcaagg gcggcctgtc cggctacccc tcgcgggcgg agtccgagca cgacgtgatc
    18961 gagaacagcc acgcctccac ggtgctcggc tgggccgacg gcctcgccaa ggccaacgag
    19021 gtgcgcggca gcgacgaccg cgtggtcgcg gtgatcggcg acggcgcgct gaccggcggc
    19081 atggcctggg aggcgctgaa caacatcgcc gccgcccggg accgcccgct gatcatcgtg
    19141 gtcaacgaca acgagcgctc ctacgcgccg accatcggcg gcctggccaa ccacctgtcc
    19201 accctgcgca ccaccgacgg ctacgagcgc ttcctgtcct ggggcaagca gctcctccag
    19261 cagaccccgg tgatcggcca gccgctctac gagtcgctgc acggcgcgaa gaagggcttc
    19321 aaggacgcct tcgccccgca gggcatgttc gaggacctgg ggctgaagta cctcgggccg
    19381 atcgacggcc acgacatcga cgccatggag tccgcactgc gccgggcccg ccgcttccac
    19441 gggccggtcc tggtgcactg cctcaccgag aagggccgcg gctacgcggc cgccgagcag
    19501 gacgaggcgg accacttcca cgccgtcggc gccatcgacc cggcgaccgg ccggccgctg
    19561 gccccctccg cggggccgag ctggacctcg gtgttcggcg aggagatggt ggccatcggc
    19621 gccgagcggc cggacgtggt cgccatcacc gcggcgatgc tccagccggt gggcctggcg
    19681 aagttcgccg ccgcctaccc gcaccgcgtc ttcgacgtcg gcatcgccga gcagcacgcc
    19741 gcgacctcgg ccgcgggcct ggccaccggc gggctgcacc cggtcgtcgc ggtctacgcc
    19801 acgttcctca accgggcctt cgaccaggtg ctgatggacg tcgccctgca caggtgcggc
    19861 gtgaccttcg tcctggaccg cgccggggtg accggggtgg acggcgcctc gcacaacggc
    19921 atgtgggaca tgtccatcct ccaggtggtg cccgggctgc ggatcgccgc gccgcgcgac
    19981 gccgaccagt tgcgggcgca gttgcgggag gcggtcgcgg tggacgacgc gcccaccgtc
    20041 gtccgcttcc ccaaggagac tgcgggcgag gcggtgcccg cgctggagcg ggtgggcggt
    20101 gtggacgtcc tggcccggcc ggccggggac ctgcggcccg acgtgctgct ggtgtccgtc
    20161 ggcgcactcg ccgggacctg cctgtcggtg gccgaactgc tgaccggccg gggcatcggc
    20221 gtcaccgtgg ccgacccgcg ctgggtcaag ccggtcgacc cggcgctgac cgaactcgcc
    20281 gccgggcacc gcatggtggc cgtcgtcgag gacaacgggc gggtcggggg cgtcggctcg
    20341 acgatcgcgc aggcgctgcg ggacgcgtcg gtggacgtgc cgctgcgcga cttcggcatc
    20401 ccgccgcagt tcctcgcgca cgccaagcgc ggcgaggtgc tggcggacat cgggctggtc
    20461 ccggcggaga tcgccgggtc cgtcggcgcg tccttcctgc ggctggccgc gcgcgccggg
    20521 cagccgtccg gtagcggcac cgaggcccgc ggtgcttccg gcgcccgtgc cgcctcgggc
    20581 gccgccgctt cgggcgccgc cgcttcgggc gccgccgcct cgggcgcccg tgccgcctcg
    20641 ggccccggcg acgcccgcga gcagggcccc gcgtccccgt ccgcggccgg cgccgggaag
    20701 gtccccggcc aggccgaccc ggcacgtccc gaagacgcct cggcggcgca tacttcgggt
    20761 ggcagcaccc cacgcacacg aggagcaggt gagcgatgac atcgtccgac ccgacgcccg
    20821 agccgggcag cccggttccc ggtgggcagc cgaaggggtt cgacctgggc acccttctcg
    20881 cggagcgggg cggtgagcgg tacgacctgc acggcaagca cctgaaccac cagttgccgc
    20941 ggatgctgca caccatcggc ttcgacaagt tctacgagcg ggccgagggc gcgcacttct
    21001 gggacgccga gggcaacgac tacctggaca tgctcgccgg gttcggtgtg atgggcgtcg
    21061 gccgccacca ccccgtggtc cgcaaggcgc tgcacgacgt gctggacgcc gggctgccgg
    21121 acctgacccg gttcgactgc cagccgctgc ccgggctgct cgcggagaag ctgctctcct
    21181 acaccccgca cctggaccgg gtgttcttcg gcaacagcgg caccgaggcg gtggagaccg
    21241 cgctgaagtt cgcccggtac gccaccggca agccccgggt gctgtactgc aagcactcct
    21301 tccacggcct gaccaccggc tcgctgtcgg tcaacggcga ggagggcttc caggacggct
    21361 tcgccccgct gctgcccgac accgagatcg aggtcggcga cctggacgcg ctggcgcgcg
    21421 agctcaagcg cggcgacgtg gcggcgatga tcgtggagcc gatccagggg cacggtgtgt
    21481 acatcccccc ggccgggtac ctgcggtccg cccagtcgct gctgcgcgcc cacaaggccc
    21541 tgctgatctg cgacgaggtg cagaccggca tcggccgcac cgggaccttc tacgcctacc
    21601 agcaggagga gggcgtcgag cccgacctgc tgacggtggc gaagacgctc tccgggggct
    21661 acgtcccggt gggcgcgacg ctcggccggg actggatctt caagaaggtc tactcctcca
    21721 tggaccgggt gctggtgcac tccgccagct acggttccaa cgcgcaggcg atggtcgcgg
    21781 ggctggccac gctctcggtg atggaggacg agcaactggt cgagaactcc cggcggatgg
    21841 gcgacctgct gcgcacccgg ctggccgcgc tcgtcgacga gtacgaactg ctgaaggacg
    21901 tgcgcggccg cggcctgatg gtcgcggtcg agttcggccg gcccaagtcg ctgaagctgc
    21961 gcggccgctg gacgatgctc caggccgccc gcaagggcct gttcgcgcag atggtggtgg
    22021 tgccgctgct ccagcggcac cgcatcctca cccaggtctc cggggaccac atcgaggtga
    22081 tcaagctgat cccgccgctg gtggtcgacg aggcggacat cgaccgcttc gtgaacgcct
    22141 tcaccgacgt catggacgac gcgcacggcg ggggcggtct gatgtgggac ttcggccgca
    22201 ccctggtgaa gcaggcggtg gccaaccggt agaacgcgcg gtcccccgtg gcgccgcgcg
    22261 ccggcgccac gggggagcgg ctcaaccggt cagcaggtgg tcctggaggc gggtgcgggc
    22321 cgcggggccc aggcacaggc cctcctccag gtagcggtcc accgagcccc agcgctcgtc
    22381 gatcgtgtcg aacgcggccc gcaggtactc gatccgggcc tcgaacagcg ggtcgagcag
    22441 cgcgcggacc tccgggtcga tcgcggtgcc ggtgctgccg tcgccgcgca ccaccttgta
    22501 gcggcggtgc cgggcgttgc tctccaggta gtccgcctcg atcgcgggcc gctgcacgcc
    22561 cagggccagc aggatgatcg ccatggaggt accggcccgg tccttgccgg cggcgcagtg
    22621 cagcagcgcc gggacggccg cgccctgcgc gggccccccg gccgggtcct ggtcggccgc
    22681 cgtcccggcg agcagggcga gcatccggcc gtgctccgag gtgcgctcca ggacgagctt
    22741 gcggtaggac gcctccatcc gccgcgcgcc ccggccgtcg ccgagcgccg cgtgcagcgc
    22801 cgcgaggtcg ccgtcgcgga cggtgtgcca gaagccggcg tgctgcgcgg gatcgctgag
    22861 cgggaggttg atgttgcggg tgcccggcag cgtgacgtcc gggccctcca gcgcgatgtc
    22921 gtcgccgttg cggaagtcga agatcgtgtg cagcccgagt gaggcgagga agtccgtgtc
    22981 ctgctcgtcg gcgtgcgcga ggtggccgct gcggaagagc acccccggcc gcacccgccg
    23041 gccgtcggcg gtgggcagcc cgcccacgtc gcggaagttg cgtaccccgg tcagccgggg
    23101 ttccggaccg gtcgtggcgg gctgccgtac gtcctgcgtc acccggtgct ccctcgtctc
    23161 tgcgtcgcgt gcgtgcgtcc cctgcgggcg cgcatggcca ccgccaagat acggcagcac
    23221 gggcaaacgc gtaccgaccg gtacgtgtcc gtctcgttcc gccggcggcg gcctgccgcg
    23281 cggcgggcgg gtgggatgaa tcacgtgccg tcaacccgtc cttacggtcg cgtaggtcac
    23341 aggccgagga gaaaaatggt gcgacgtggc tgacgatacg cggacaacag acgactacgg
    23401 agagaccgac ggggagcgac cggcgccgca cgggccgacg agcggaccgg gcctcgtgct
    23461 cgcgcccgcc gcggccgggt tcgggtcgta cgcggcggtc ggggacagct tcacggaggg
    23521 cgtcggcgac cccgggcccg gcgaggcgtt cgtggggtgg gcggaccggc tggcggggct
    23581 gctcgccggc cgccgggccg agggcggccc gcccggcgcc ttccgctacg ccaacctcgc
    23641 ggtgcgcggc cggctgctgg accggatcat cgacgagcag gtgccccggg cggtgacgct
    23701 cgcgcccgac ctggtcacct tctgtgccgg cggcaacgac atcctgcgcc cgggcagcga
    23761 ccccgacgcg ctcgccgagc ggttcgaggg cgcggtggcg gacctgcgcg cggtggtggg
    23821 cacggtgctg gtctgcaccg gcttcgacac ccgcggggtg cccgtgctgg gcctgctgcg
    23881 cggcaagatc gcgacgtaca acgcgcacat ccgggcggtc gccgaccgct acggctgccc
    23941 ggtgctggac ctgtggtcgc tgaggtccat ccacgaccgg cgggcctgga gcgaggaccg
    24001 gctgcacctg tcctcggccg ggcacgcgcg ggtggcgctg cgcgccgccc aggtgctcgg
    24061 gatcgagacg ccgtccgacc cggacctgcc ctggccgccc gagccgctcc ggctgcccgc
    24121 gcaggtccgg aaggacaacc tccactgggc ccgcgagtac ctggtgccgt ggatcggccg
    24181 ccggctgcgc ggggagtcct ccggcgacga cgtgctgccc aagcggccgg aactgctgcc
    24241 gctggagccc gcccgactgg agtcctgccg ctgatcgggg ccggccgctc gccggagcgg
    24301 tgagcggtcg ctcccggtcg ggcggggcgg gtggcgcggg agaggcggtg cgttgcccgg
    24361 tgcgtcagcg gggcgcgtgc ccggtatgtc agcggggcgc gtggtgtgcg gccagttcgg
    24421 cccacaccac gcgcccccgt gccgtccgct gcggggtcgg agccccaggc cgtcgccagc
    24481 acgctcacca gcagcaggcc gcggccgccc tcctcgtcgt cggtggccgt acagggcacc
    24541 gggctcgcgc cgccgcaccc ctggtcggtc acctccagcc gcaccgccga gccgacgtcg
    24601 cgcagcgcgc acgtgatctg ccggctgtcg gtgtgccgga cggcgttggt gaacagctcg
    24661 gtcaccacca ggccggcgtc gtccctcagt tccgcgtccg cgccccattc ccgcagccgg
    24721 gcccgtatcc gggcgcgggc gtccgccacg gacgcgctca tcgcgggcaa ccggaagacg
    24781 tcctggcgcg tacaggcgcg gacgtccgcc cggtgtccgg gtcggagggc gtgagttgaa
    24841 aggaccaccc cgtaactatg ggccccgccc tggacacatg gcaaggtccg aactgtaaat
    24901 tacagaatcg acagaacatg ctgttcctgg cgctgacgtc atgacacact gcttgtcagt
    24961 caagggagtt ggaggttgag gcacgtgatg gaccccaggc cgggcggtgc gccgacggtc
    25021 ctgcgcatgg tgctcggcaa gcgactccag gacctccgtg agaaggccgg cctcagcttc
    25081 gagcaggccg ggcgcgccct tgatgtgaca cacgccacga tccggcggat ggagaaggca
    25141 gaagtcgggc tgaagatccc gtacgtcgag aagctgctca ccacgtacgg ggtcaccgcc
    25201 cccgacgaga tcggcggctt cctcgcgctg tgccgcgagg ccaaccggcc cggttggtgg
    25261 cacaacttcc gcgacgtgct gcccgagtgg ttcagcgcct tcgtcagcct cgaaggcgag
    25321 gcgtcggtca tccgcgccta cgaaccgcac tacgtccccg gactgctcca ggtccccagc
    25381 tacgcccagg ccgtgctgcg tgccggcctg cccaacgcca catccgagga gatcgaccgg
    25441 ctggtcacgc tgagggtgga gcggcaggcg ctgctctccc gcgccgaggc gccgctgctg
    25501 tgggtcgtga tggacgagac ggtgctgcgc cggccgatcg gcggcccgaa ggtgatgcgc
    25561 gagcaggtgg gtgccctgat ggacgccgcc gacctgccga acgtgcgcct ccaggtgatc
    25621 ccgttcgccg cgggcccgca cccggccatg tacgggccgt tccacatctt ccggttccag
    25681 ctcaaggaga tcccggacat cgcctacacc gagagtctgg tgggcggcgc ctacttcgac
    25741 gaccgggacg acgtgtccac cttcctcgag gccctcgacc ggatgtgcgc gcaggcagcg
    25801 ccggcacaga gcaccaaagc catcctcgat ggcatgcgca aggagatctg aaccatggat
    25861 cgcgtcacca acgacagcat ctacaacgga atgcccgccg cggaactcgg cgcggacggc
    25921 tggcggaagc cctggagcgg cggcaacggc ggctcctgcg tggaggccaa gcgcctcaac
    25981 gacggccggg tggcgctgcg ccagtccacc gaccccgagg gccccgcgct catctacacc
    26041 aaccacgaga tcacctcgtt catccagggc gccaaggccg gcgacgcgga cttcctgctc
    26101 ggatgaccgg gacccgacgc cggcccggcc ggctccgaca ccccgaccag gacacgacga
    26161 agcggaggac cgcgtgaccg agcagggctt tcccgccggt gagatcgaca catcccggcc
    26221 gcacccggcc cggatgtacg actactacct cggtggcaag gacaactacg aggtggaccg
    26281 ggaagccgcc gaccgcgtgg tggacgccgt gcccgaggtg gtcgtcgggg cccgcgcgaa
    26341 ccgggacttc ctccagcggg cggtgcgcta cctcgccgag cacggggtgc gccagttcat
    26401 cgacataggc accggcatcc cgacctcgcc gaacacccac gagatcgccc actcggtcgc
    26461 gcccgacgcc cggatcgcct acatcgacaa cgacccgatc gtcgccaccc acgccggcgc
    26521 ccgactgctc ggcaccggca acaccggctt cttcctcgcc gacatgcgcg acccgcagac
    26581 gatcctgaac caccccacca tccgggagct gatcgacttc ggacagccgg tcgccctgat
    26641 gctggtgtcg gtgctgcact tcgtcaccga cgaggagaac ccgcgcgaga ccgtcgccac
    26701 gctgcgcgac gccatgcccg agggcagcta cctggtgctc tcgcacgcca ccgccgactt
    26761 caacgccggc aaggccgacg aggtcaccac ggtctacaag aaggccaccg cgctgctcac
    26821 cccgcgcacc cacgccgagg tgctggac
//
