LOCUS       NZ_AP018365            45163 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  Streptomyces sp. SN-593 chromosome.
ACCESSION   NZ_AP018365
VERSION     NZ_AP018365.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. SN-593
  ORGANISM  Streptomyces sp. SN-593
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Panthee,S., Kito,N., Hayashi,T., Shimizu,T., Ishikawa,J.,
            Hamamoto,H., Osada,H. and Takahashi,S.
  TITLE     beta-carboline chemical signals induce reveromycin production
            through a LuxR family regulator in Streptomyces sp. SN-593
  JOURNAL   Sci Rep 10 (1), 10230 (2020)
   PUBMED   32576869
  REMARK    DOI:10.1038/s41598-020-66974-y Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Takahashi,S., Toyoda,A., Sekiyama,Y., Takagi,H., Nogawa,T.,
            Uramoto,M., Suzuki,R., Koshino,H., Kumano,T., Panthee,S., Dairi,T.,
            Ishikawa,J., Ikeda,H., Sakaki,Y. and Osada,H.
  TITLE     Reveromycin A biosynthesis uses RevG and RevJ for stereospecific
            spiroacetal formation
  JOURNAL   Nat Chem Biol 7 (7), 461-468 (2011)
   PUBMED   21642985
  REMARK    Publication Status: Online-Only
REFERENCE   3
  AUTHORS   Panthee,S., Takahashi,S., Takagi,H., Nogawa,T., Oowada,E.,
            Uramoto,M. and Osada,H.
  TITLE     Furaquinocins I and J: novel polyketide isoprenoid hybrid compounds
            from Streptomyces reveromyceticus SN-593
  JOURNAL   J. Antibiot. 64, 509-513 (2011)
REFERENCE   4
  AUTHORS   Takahashi,S., Takagi,H., Toyoda,A., Uramoto,M., Nogawa,T., Ueki,M.,
            Sakaki,Y. and Osada,H.
  TITLE     Biochemical characterization of a novel indole prenyltransferase
            from Streptomyces sp. SN-593
  JOURNAL   J Bacteriol 192 (11), 2839-2851 (2010)
   PUBMED   20348259
REFERENCE   5  (bases 1 to 8833490)
  AUTHORS   Takahashi,S., Ueki,M., Toyoda,A., Ishikawa,J., Sakaki,Y. and
            Osada,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2017) Contact:Shunji Takahashi Chemical Biology
            Research Group, RIKEN Center for Sustainable Resource Science
            (CSRS); Hirosawa 2-1, Wako, Saitama 351-0198, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Phrap v. 0.990329
            Genome Coverage                   :: 16x
            Sequencing Technology             :: ABI 3730
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016756395.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 03:58:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,420
            CDSs (total)                      :: 7,334
            Genes (coding)                    :: 7,181
            CDSs (with protein)               :: 7,181
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 153
            CDSs (without protein)            :: 153
            Pseudo Genes (ambiguous residues) :: 0 of 153
            Pseudo Genes (frameshifted)       :: 35 of 153
            Pseudo Genes (incomplete)         :: 136 of 153
            Pseudo Genes (internal stop)      :: 8 of 153
            Pseudo Genes (multiple problems)  :: 25 of 153
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:29:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1429831
            Orig. end                         :: 1474994
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP018365.1.
            This work was done in collaboration with Shunji Takahashi, Masashi
            Ueki, Atsushi Toyoda, Yoshiyuki Sakaki and Hiroyuki Osada (RIKEN)
            and Jun Ishikawa (National Institute of Infectious Diseases).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..45163
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="10"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..45163
                     /SMILES="C(C)C(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..45163
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:25163](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..25163)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(638..1264)
                     /locus_tag="RVR_RS06055"
                     /old_locus_tag="RVR_1710"
     CDS             complement(638..1264)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025605.4"
                     /locus_tag="RVR_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1710"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_202232860.1"
                     /transl_table=11
                     /translation="MTARDNEGAAAPQTARKRGRPTAAERAQRRDEILDAAVRLFVAGG
                     FEQVTLDDIAARAHVTKRTIYAYVGDRTEIFLAAVERLRERALEQPVREDGLVDLAAKI
                     VFALHGDEAVGLHRLMITEAHRFPDLARRFYDDGPRGYVAALADRLTPPDPETAEALFA
                     LLLGEPHRRRLLGLAPAPTRQAAAAHARSAVGRLVRPVPPEGPAA"
     misc_feature    1305..1318
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.56"
                     /tool="antismash"
     gene            1438..2691
                     /gene="pdhA"
                     /locus_tag="RVR_RS06060"
                     /old_locus_tag="RVR_1712"
     CDS             1438..2691
                     /EC_number="1.2.4.1"
                     /GO_component="GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA]"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /gene="pdhA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145137.1"
                     /locus_tag="RVR_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1712"
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="WP_202232861.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-10, bitscore:
                     39.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPTTRASAAGNPPDRGARAQGGGRSGRRRAAAGTAGPGAPAAEG
                     EVRAGSGGEAPADAEAGPGTGGEALADAELLAFYRQMVLVRRFEERAARAYTEAKVGGY
                     CHLNLGEEATVAGLMAAARSEDYVFTNYREHGYALARGIAPERVMAELYGRTDGVSKGW
                     GGSMHMFDVASRFMGGYGIVGGQVPLATGAALAVDYRGGTEAVVCLMGDGTTNIGAFHE
                     SLNIAALWGLPVVYVVVNNGLGMGTTVEQSSAEPELHKRAASYRMASARVDGNDPVAVF
                     RAARTALDSARAGRPYLLETVSGRLKGHSVVDPARYRTREEAEALRAADPIAAYAVRLH
                     RQGVLTDELIERIDAEATAAVTAAAAFADASPHPDVSTLFDYTYATPVPNDSRRLPGEA
                     LFPAPPRPVGASPAGVPA"
     gene            2688..3680
                     /locus_tag="RVR_RS06065"
                     /old_locus_tag="RVR_1713"
     CDS             2688..3680
                     /EC_number="1.2.4.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145136.1"
                     /locus_tag="RVR_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1713"
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="WP_202232862.1"
                     /transl_table=11
                     /translation="MSVISYRQALHAALHDEMLRDERVFLIGEEIGRFEGSYKITAGML
                     DAFGPRRVRDTPIAEEGFTGAAIGAAMVGLRPVVEIMTINFSLLALDQIVNHAAKVYGM
                     FGGQARVPLVIRTPGGGGQQLGATHSQNIELYYAFVPGMKVVAPSSPADAKALMLAAIR
                     DDDPVLVLENLALYNTTGEVPDDLGPAPIGRAAVTREGADITVVAYSRMAAVALQVAER
                     LAGEGIDVEVVDLRSLRPLDRESIVASVRKTGCAVVLEDDWLTYGIGAEVAATIGDGAF
                     DWLDAPVRRVAMAEVPLPYAKTLETAALPSADDAAAAIRETLDAVARRR"
     gene            3707..5146
                     /locus_tag="RVR_RS06070"
                     /old_locus_tag="RVR_1714"
     CDS             3707..5146
                     /EC_number="2.3.1.-"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012424.4"
                     /locus_tag="RVR_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1714"
                     /product="dihydrolipoamide acetyltransferase family
                     protein"
                     /protein_id="WP_202232863.1"
                     /transl_table=11
                     /translation="MIDILMPRLSDTMTQGVVAAWLKQPGDTVSPGDVLVEIETDKALM
                     EHEAYDAGTLAEILVPEGGSAPIGAPIARLDDGASVAAGAGADAMGDGARAGAGTGTGA
                     PGDAAGGPVGGAGSVTGTGTGGSGGSGSGGTPGAAGASGPGPAAAEDHTEAGSPSGPPT
                     TAPDLPERRAATPLVRRLARERDIDLATVAGTGPGGRIVRADIDALDTLAALAAPEAPG
                     GQGAVDAVNALDAAAAPGTAKTPDGREPRPVPFDPIRRAIAARLTESGTTVPTFTATAS
                     ADVGDLLALRGRINASRAEDGVKVSVNDLLVRAVALALRGHPGVNASYSPDGQGQTLLH
                     GRVHVGVAVASPAGLVVPVVRDADRASVTAIAAATRDLVAKAAERRLAAADMGDGTFTV
                     SNLGMYGVEHFTAIINPPQGAILAVGAAGDELALAGGEVVTRKRLRYTLTADHRVIDGA
                     LAAQFLKTLTELLENPLRIVA"
     gene            complement(5244..5600)
                     /locus_tag="RVR_RS06075"
                     /old_locus_tag="RVR_1717"
     CDS             complement(5244..5600)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RVR_1717"
                     /product="hypothetical protein"
                     /protein_id="WP_202232864.1"
                     /transl_table=11
                     /translation="MPKTVIHVFHDDDDALATGTRVAQRIHEVAQERGSEVEVFCFGPA
                     QRRLGEEGGSAAVLTFNRQIDELVAAGVVVGACVNSARADGVEDLLTGRGLRLRVARDE
                     FVRFTLEQATVVSF"
     misc_feature    5676..5690
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            complement(5757..6326)
                     /locus_tag="RVR_RS06080"
                     /old_locus_tag="RVR_1718"
     CDS             complement(5757..6326)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RVR_1718"
                     /product="hypothetical protein"
                     /protein_id="WP_202232865.1"
                     /transl_table=11
                     /translation="MSQEHGRKRSGRRTARLLTGAALALATTVGAAGAAGAAAPNADRS
                     AAGYLSASHAAPATVVSPAVATTSFTHTSTTAPYYTITCTLTASDPLRYYGGAYPGGGV
                     EAIGSVQCNNLVNTIAVQVALVKNSSVVARSTVRYSYSTNLGGQTTDTPHGAGTYITAA
                     VTGITFPDGYYWASPEVDSPSLYIAS"
     misc_feature    complement(7326..7341)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.6"
                     /tool="antismash"
     misc_feature    complement(7331..7344)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.74"
                     /tool="antismash"
     gene            7339..7509
                     /locus_tag="RVR_RS06085"
                     /old_locus_tag="RVR_1720"
     CDS             7339..7509
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673915.1"
                     /locus_tag="RVR_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1720"
                     /product="hydrophobic protein"
                     /protein_id="WP_202232866.1"
                     /transl_table=11
                     /translation="MGPLLLVLLLALILFGAGFALKILWWVAVVVLVVWLLGFVVRSTH
                     SGGGRSRWYRW"
     gene            7707..7892
                     /locus_tag="RVR_RS06090"
                     /old_locus_tag="RVR_1721"
     CDS             7707..7892
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575508.1"
                     /locus_tag="RVR_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1721"
                     /product="CsbD family protein"
                     /protein_id="WP_202232867.1"
                     /transl_table=11
                     /translation="MSTDDKTKAKVEQGKGKLKETAGRAVGNERLEAEGRAEQAKGDVR
                     AAGEKAKDAAKDAFGN"
     gene            complement(8001..8333)
                     /locus_tag="RVR_RS37355"
     CDS             complement(8001..8333)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS37355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237404597.1"
                     /transl_table=11
                     /translation="MVTAFARSPGSRKTTAVTSASSFTRSVFAASQPSLVYASRISCSG
                     GPSVGICRTWSVTLIRSTQGLLGAPRVDLDQILDRVVAVAKIAGTPEYRQPILDAALAG
                     LVGCDG"
     misc_feature    complement(8777..8792)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.83"
                     /tool="antismash"
     gene            9163..>9393
                     /locus_tag="RVR_RS06105"
                     /pseudo=""
     CDS             9163..>9393
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607936.1"
                     /locus_tag="RVR_RS06105"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DCC1-like thiol-disulfide oxidoreductase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTRPVVVFDGDCAFCTASVQFGERWLRPRCDFTPWQRADLRSLG
                     LEQQRAEYEVLWVTPAGVVYGGVQAVAQLLLS"
     gene            10084..10650
                     /locus_tag="RVR_RS06110"
                     /old_locus_tag="RVR_1725"
     CDS             10084..10650
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129267.1"
                     /locus_tag="RVR_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1725"
                     /product="DUF5819 family protein"
                     /protein_id="WP_202232870.1"
                     /transl_table=11
                     /translation="MLVCFALLHLFFLFLHVAPENQISRRYAGQIQSWVFPFFEQNWRL
                     FAPDPESAVPQISVRTAHTSADGHYQVSAWFDLTAIDNAGVRHNPFPSHTTQNMLRRAW
                     TGYLDSHSTSDVSYTDRAKMWQEYLRNIAVDRVDTRPGAVEWVQLRVRTSPVPNYDAAG
                     HTHPLPPSAVDTRKLPWWKVTAHDH"
     gene            10676..11809
                     /locus_tag="RVR_RS06115"
                     /old_locus_tag="RVR_1726"
     CDS             10676..11809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129266.1"
                     /locus_tag="RVR_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1726"
                     /product="HTTM domain-containing protein"
                     /protein_id="WP_202238420.1"
                     /transl_table=11
                     /translation="MSTGPGLVRAARASLGGLITLLTTRHVSLYAAAVLRFGYGLCYLV
                     FLLREFPHRDEIWGPDSPWTPALAHQLFAQTGWFSFLTLSNSLIYFDFCYAAAIIVCAL
                     FLLGWRTRAMSVAFALVVASFHARAIFMTDGGDNLVLLMALYLTATACGRRWSLDARRE
                     DRRVRPRGRAPRQAGNDVWTPLSLARQPVVTALHNCGMFVICAQVCLLYGSAGLYKVQG
                     SSWQSGTALHYVVNLDLFRPWPALSALLDHYPLLLAVLGYLTVLIQVAFPFALFSRLKY
                     VLLVMLLAMHLGIAVLLGLPLFSAAMIVADAAFLPDRFYRAAAHTARRVLDRLRTHAST
                     TPSPHVAMVPSQPGEPGLPRSGDDPALPAGVRARGQK"
     gene            12406..12564
                     /locus_tag="RVR_RS06120"
     CDS             12406..12564
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_202232871.1"
                     /transl_table=11
                     /translation="MPNGSVLVSRRSRSRASSAASSKPRSTSRRRPKISPRSVSQQPSS
                     TPGAPAA"
     gene            <12573..>12710
                     /locus_tag="RVR_RS38855"
                     /pseudo=""
     CDS             12573..>12710
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262570.1"
                     /locus_tag="RVR_RS38855"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="electron transfer flavoprotein subunit beta"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRKALSMGADRGVHVEDDALHGTDVIGTSLVLAKAVEHVGFDLVV
                     T"
     gene            <12709..>12972
                     /locus_tag="RVR_RS06130"
                     /pseudo=""
     CDS             12709..>12972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884313.1"
                     /locus_tag="RVR_RS06130"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="electron transfer flavoprotein subunit alpha/FixB
                     family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGAVRVLAADAPEFADYLVVPKVDALQAAVAAVEPLAVLVPSSAE
                     GKEVAARLALRIGPGILTDAVDVEAGGEGVVATQSVFAAAFTT"
     gene            complement(13307..14020)
                     /locus_tag="RVR_RS06135"
                     /old_locus_tag="RVR_1732"
     CDS             complement(13307..14020)
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013950.4"
                     /locus_tag="RVR_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1732"
                     /product="G1 family glutamic endopeptidase"
                     /protein_id="WP_202232872.1"
                     /transl_table=11
                     /translation="MRRFLIRVATVAAAAAFAAPAVPATAAAAPGLSFRPLHYNINGYN
                     WGGYAATGSGFTSVSAAWTEANATCNSTNDLYAPWVGIDGYGSSTVEQTGVATDCSSGS
                     PVHQAWYEMYPASPVYLSRTSYPVAAGDHITASVTNTSGSTYALKLTDSTRGWTYSINK
                     SLSAQRASAEVIIESPTGAYPNFGTLNFTSATVNGSSLGSYGPTALDPSNGAYEARTSA
                     LGTSGTSFSETYLRE"
     misc_feature    14094..14108
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    14108..14125
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 13.91"
                     /tool="antismash"
     gene            14199..14555
                     /locus_tag="RVR_RS06140"
                     /old_locus_tag="RVR_1733"
     CDS             14199..14555
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RVR_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RVR_1733"
                     /product="hypothetical protein"
                     /protein_id="WP_202232873.1"
                     /transl_table=11
                     /translation="MAYPGDSVEADEVADAVGGEVPVEGNRQCGTEDHGEQQSGEADRG
                     HGAAGDAAAAQGIELSPRSPRAIRLWAKGRARALARQGDCAGTARAIGRALDLTTTASA
                     PPAAVMARLRTLKG"
     misc_feature    complement(14236..14250)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(15029..15994)
                     /locus_tag="RVR_RS06145"
                     /old_locus_tag="RVR_1735"
     CDS             complement(15029..15994)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059009.1"
                     /locus_tag="RVR_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1735"
                     /product="pirin family protein"
                     /protein_id="WP_202232874.1"
                     /transl_table=11
                     /translation="MSNLDVKPSASVCGGREDVSAAPVRELLTGRITPLGESTRVRRLL
                     PNLGRRMIGAWCFVDHYGPDDIAREPGMQVPPHPHTGLQTVSWLHDGEVLHRDSLGSKQ
                     TVRPRELGLMTSGRGISHSEESPRDHGRYLHGAQLWVALPDAHRNTEPAFEHHAELPEV
                     TAHGLHATVILGELDGAVSPGTVHTPLVGADLTLAEGTAARLPLQPDFEYAALAMSGRV
                     DVDGVAVTPGSLLYLGAGRRDLSLLADSSASLMLLGGEPFAEKLVMFWNFVGRTGEDIA
                     QAREDWHTGNRFGEVHGYDGDRLLAPELPPTPLKPRGRER"
     misc_feature    complement(15973..15987)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 15.9"
                     /tool="antismash"
     misc_feature    complement(15980..15994)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            complement(16002..17969)
                     /locus_tag="RVR_RS06150"
                     /old_locus_tag="RVR_1736"
     CDS             complement(16002..17969)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016472454.1"
                     /locus_tag="RVR_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1736"
                     /product="acyclic terpene utilization AtuA family protein"
                     /protein_id="WP_202238421.1"
                     /transl_table=11
                     /translation="MRIANCSGYYGDRLAAAREMVEGGPIDVLTGDYLAELTMLLLWKA
                     RRRDPDGGYALSFLAQMHDVLGTCLERGIKVVVNAGGLNPAGLAAKLRELAAAAGLRPS
                     VAHVEGDDLLGRLPELRSRGHAFAHLATGRPLAAAGVEPVTANAYLGGWGIARALRSGA
                     DVVVCGRVTDASLVVGPAAWAFGWAPDDWDALAGAVTAGHIIECGTQATGGNYSFFTEI
                     PDPVHPGFPIAEVHPDGSSVITKHPGTGGAVTVGTVTAQLLYETGHPAYLNADVVARFD
                     TVRLTQEGTDRVAVGPVTGEPAPDTLKVCVNHVGGHRNSAVFVLTGLDLDAKADFAEAA
                     LRDATGGPAAFAGYDLRREHGHEVDRLTLTVKDPDPGKVGRGFFSAVAGTALAGYPGLY
                     LEHATARPTEYGVYWPALVPAEEVAEVAVLADGTRLAVPRAGGPGRSGAEGPGAEGAAS
                     GAVPPGAVPPGAVAAGAVPPGAVAVGGGPGGGLLPGRVAPGVRPDAVPPPPPPVAGAPR
                     PERAEPYGGRTGAEPGRTVRLPLGTLVGARSGDKGGDANVGLWVADDDAYAWLRTYLDV
                     PRLRALLPEAARLPVSRYELPNLRALNFVVHDLLGDGVAASTRADPQAKALGERLRGRL
                     ADIPERLVEPPRAPRPQPGA"
     gene            18169..18777
                     /locus_tag="RVR_RS06155"
                     /old_locus_tag="RVR_1740"
     CDS             18169..18777
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059584.1"
                     /locus_tag="RVR_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1740"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_202232875.1"
                     /transl_table=11
                     /translation="MNQPPARPDPAERPDPAERPDAGAPDDDGGPLSVHEVIDIVDEDD
                     HVVGTSPRGEAYARGLRHRCAFILARDDRDRIFVHRRTSRKLVFPSLYDVFVGGVVGAG
                     ESYDETALREAEEELGVSGLPQPTRLFKFLYRQENGPGGWWSTVYEVRVDGPVRPQPEE
                     VAWHAFVTEEELETRLREWEFVPDGLEAYRRLARWRAER"
     gene            complement(18830..19843)
                     /locus_tag="RVR_RS06160"
                     /old_locus_tag="RVR_1743"
     CDS             complement(18830..19843)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627209.1"
                     /locus_tag="RVR_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1743"
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="WP_202232876.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 3.7e-06, bitscore:
                     25.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTHRRLPGAAAALAVTLAASAALVLGPAGPAPAATAREGAAAVP
                     AGTAADGASVVSQTWLDARTVDLRISSPAVGGTVSTRLLLPADWSAQAGRTWPVLYLLQ
                     GAHDDYTSWTRETDIEQFTADKEVIVAMPSSGPTGIPSAWWNYGSGHPDYETFQVTELM
                     QLLQQDYRAGATRAIGGVSTGGWAAMAFAARHPGTFAAAASYSGVLDTTMPGMPTVVEA
                     IVAREGLDPMSLWGSPVLNFPLWNAENPFALASGLQGTKLFLSSGTGVVGGNGELSAEA
                     LETTLWPGSQAFAVRLALLGLPVQTHFYTGGTHSWTYWKQEYKTSWPVIAQALGLT"
     gene            complement(20001..25163)
                     /locus_tag="RVR_RS06165"
                     /old_locus_tag="RVR_1745"
     CDS             complement(20001..25163)
                     /NRPS_PKS="Domain: ACP (5-66). E-value: 6e-15. Score: 47.3.
                     Matches aSDomain: nrpspksdomains_RVR_RS06165_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (114-587). E-value:
                     4.2e-150. Score: 492.3. Matches aSDomain:
                     nrpspksdomains_RVR_RS06165_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (775-1068). E-value: 3.1e-82.
                     Score: 268.2. Matches aSDomain:
                     nrpspksdomains_RVR_RS06165_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (1196-1262). E-value:
                     2.1e-19. Score: 61.6. Matches aSDomain:
                     nrpspksdomains_RVR_RS06165_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005475279.1"
                     /locus_tag="RVR_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1745"
                     /product="type I polyketide synthase"
                     /protein_id="WP_202232877.1"
                     /sec_met_domain="hyb_KS (E-value: 9.8e-152, bitscore:
                     504.4, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.9e-66, bitscore:
                     222.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.7e-80, bitscore: 268.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-15, bitscore:
                     54.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1e-14, bitscore:
                     54.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARLGAWYGLDPSDIDDDRPFAELGLTSRDAVALSGELRALTGVP
                     LAPTALWDATTLGRLLGALAEGGAAQDAAAHPRPELSVPGPAGGPGRGPEHGSERAPEP
                     GPGRGPAAVPVAVVGLGCRLPGGATSPAALWELLREGRDAVGTVPDDRWAPFLPPAVGS
                     RAGRRPGEPGPGGPGAGGPGVNLAQPDRAAPGGQGATGGAESASGPGEPGPGGPGLEGV
                     SRHGAFLPDIAAFDAEFFGISPHEAVRMDPQQRLLLEVAREGLDHAAIPATELAGTATG
                     VFVGISGNEYASLTTADLGAVDAWTPPGAALSIAANRLSYALDLRGPSMAVDTACSSSL
                     VAVHHAVRSLATGETDTALAAGVNLLLSPALTLAFQRAGALAPDGRCKTFDASADGMVR
                     GEGCVVAVLKRLADAERDGDRVLAVVHGTAVNSDGRSNGLLAPNPAAQRALLRQAHGPR
                     GALLDYVEAHGTGTALGDPIEAQALGAVLGTGRDPDQPLLIGSAKTNFGHLEAAAGMVG
                     LAKTVLALHHGLLPAHLHLTEPNPLIDFDALGLRVVTAPEPWPRYSGTATAGVSAFGFG
                     GTNAHVTLAEYRPTGPCPPAALHRPAHASGPAAAPSSAPTPEPVTAAAPGDAATAPLPG
                     PEPATAAAAARWPEPVTAAARRPAPVVVAEPPPAVLVLDAPSDARLRAAAEALARWLAS
                     PPGRAVPLRDLARTLHGRTGRGRHRAAAVAADHDEAAAALARLATGRPHPALARPAPPP
                     PDGPRPAYPPSPSNGGAPRPVWVFSGYGSQWPGMGRRLLAAEPAFAAAVDRLEPLLERH
                     AGLSLRAHLRPDADLATPSVVQPVLFGLQVALAGLWRWYGVEPAAVIGHSMGEVAAAVV
                     AGAIDEESGARVIGTRARLLDGLSGGAMAVVELSAAEVRRHAATFPSVRVAVHSSPAQS
                     VVTGTAADIDNLVAMVRRLGGLARPLRVVAAGHSPQVDPLLAPLTRQLGEVPHTVPGRA
                     FYGTVLDDPREVPAFDAGYWAAGLRQPVRFAQAVAAAAEDGHRTYVEISAHPTQLHPLA
                     ETLAAQGIEGAVLLPTLRRNTDDARTFRTGLAAHLLHGTAVARDLLHPGARPADVPSAG
                     WRHRRYWVETATAVHRRGPEPAAAPGEFGAAATGTDGDAPAAGFTAGAAAKPLSGPPSG
                     PPSGPPSEPAAGSPGAGGAVAASGAPTVLGRLLGHVAQVMGYAPTDIDPRTPLTDLGLD
                     SLMAARILAAVGRDFGVAVEPRVLLRHGTVEALAAWLARHGDDPADAATGAPADAATGA
                     PADAATGAPADAATGVLADTAPPVPVPPTPPVTEPAASTRPSEDAAAPARSGQNGRRRR
                     IQPRDAAERLVAHAWATVAGGPPPGAEDDLGLPGRPFDDVARFAAELTGRSGYRVAPGE
                     LLTRPPTVSAVAELLRPRLESATGGPVRTLSAAGTGAPLFLFHPAGGSSAVYGGLVRRL
                     GPDRPCYGLDRLPALADVGDRARAYARTIRDVRPNGPWVLGGWSYGGLLAQETARLLAA
                     PEDTAPEPHRDPRRRTTPGAVAALVLVDSVLPLPAPRLTPRDEALRRFSGFARYVEETY
                     GARLDLPYDRLAALDDAGQVDLVVGALARSADLPAAVLEHQRASYLDLRSAERHTPRPY
                     AGRTLLYRATEPAPHTVRDPRYDRDDPALGWDAHCRDLTVRPLPGHHLALLDPPVVDEL
                     AALLARDLAGGATEPPRPEPGER"
     CDS_motif       complement(20139..20159)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0011"
                     /evalue="4.40E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="RVR_RS06165"
                     /protein_end="1675"
                     /protein_start="1668"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="WDAHCRD"
     CDS_motif       complement(20610..20681)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0010"
                     /evalue="5.50E-11"
                     /label="NRPS-te1"
                     /locus_tag="RVR_RS06165"
                     /protein_end="1518"
                     /protein_start="1494"
                     /score="34.8"
                     /tool="antismash"
                     /translation="PNGPWVLGGWSYGGLLAQETARLL"
     CDS_motif       complement(20817..20846)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0009"
                     /evalue="1.30E-02"
                     /label="NRPS-beforete1"
                     /locus_tag="RVR_RS06165"
                     /protein_end="1449"
                     /protein_start="1439"
                     /score="8.7"
                     /tool="antismash"
                     /translation="PLFLFHPAGG"
     aSDomain        complement(21378..21575)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS06165_PP-binding.1"
                     /evalue="2.10E-19"
                     /label="RVR_RS06165_PP-binding.1"
                     /locus_tag="RVR_RS06165"
                     /protein_end="1262"
                     /protein_start="1196"
                     /score="61.6"
                     /tool="antismash"
                     /translation="RLLGHVAQVMGYAPTDIDPRTPLTDLGLDSLMAARILAAVGRDFG
                     VAVEPRVLLRHGTVEALAAWL"
     aSModule        complement(21378..24821)
                     /complete
                     /domains="nrpspksdomains_RVR_RS06165_PKS_KS.1"
                     /domains="nrpspksdomains_RVR_RS06165_PKS_AT.1"
                     /domains="nrpspksdomains_RVR_RS06165_PP-binding.1"
                     /locus_tags="RVR_RS06165"
                     /monomer_pairings="mmal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(21960..22838)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS06165_PKS_AT.1"
                     /evalue="3.10E-82"
                     /label="RVR_RS06165_PKS_AT.1"
                     /locus_tag="RVR_RS06165"
                     /protein_end="1068"
                     /protein_start="775"
                     /score="268.2"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFSGYGSQWPGMGRRLLAAEPAFAAAVDRLEPLLERHAGLSLRAH
                     LRPDADLATPSVVQPVLFGLQVALAGLWRWYGVEPAAVIGHSMGEVAAAVVAGAIDEES
                     GARVIGTRARLLDGLSGGAMAVVELSAAEVRRHAATFPSVRVAVHSSPAQSVVTGTAAD
                     IDNLVAMVRRLGGLARPLRVVAAGHSPQVDPLLAPLTRQLGEVPHTVPGRAFYGTVLDD
                     PREVPAFDAGYWAAGLRQPVRFAQAVAAAAEDGHRTYVEISAHPTQLHPLAETLAAQGI
                     EGAVLLPTLRRN"
     CDS_motif       complement(22107..22154)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0008"
                     /evalue="1.30E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="RVR_RS06165"
                     /protein_end="1019"
                     /protein_start="1003"
                     /score="11.4"
                     /tool="antismash"
                     /translation="FDAGYWAAGLRQPVRF"
     CDS_motif       complement(22491..22610)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0007"
                     /evalue="1.20E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="RVR_RS06165"
                     /protein_end="891"
                     /protein_start="851"
                     /score="43.1"
                     /tool="antismash"
                     /translation="GVEPAAVIGHSMGEVAAAVVAGAIDEESGARVIGTRARLL"
     CDS_motif       complement(22614..22670)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0006"
                     /evalue="2.30E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="RVR_RS06165"
                     /protein_end="850"
                     /protein_start="831"
                     /score="20.4"
                     /tool="antismash"
                     /translation="VVQPVLFGLQVALAGLWRW"
     CDS_motif       complement(22788..22844)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0005"
                     /evalue="3.60E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="RVR_RS06165"
                     /protein_end="792"
                     /protein_start="773"
                     /score="19.3"
                     /tool="antismash"
                     /translation="VWVFSGYGSQWPGMGRRLL"
     aSDomain        complement(23403..24821)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS06165_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="4.20E-150"
                     /label="RVR_RS06165_PKS_KS.1"
                     /locus_tag="RVR_RS06165"
                     /protein_end="587"
                     /protein_start="114"
                     /score="492.3"
                     /tool="antismash"
                     /translation="VAVVGLGCRLPGGATSPAALWELLREGRDAVGTVPDDRWAPFLPP
                     AVGSRAGRRPGEPGPGGPGAGGPGVNLAQPDRAAPGGQGATGGAESASGPGEPGPGGPG
                     LEGVSRHGAFLPDIAAFDAEFFGISPHEAVRMDPQQRLLLEVAREGLDHAAIPATELAG
                     TATGVFVGISGNEYASLTTADLGAVDAWTPPGAALSIAANRLSYALDLRGPSMAVDTAC
                     SSSLVAVHHAVRSLATGETDTALAAGVNLLLSPALTLAFQRAGALAPDGRCKTFDASAD
                     GMVRGEGCVVAVLKRLADAERDGDRVLAVVHGTAVNSDGRSNGLLAPNPAAQRALLRQA
                     HGPRGALLDYVEAHGTGTALGDPIEAQALGAVLGTGRDPDQPLLIGSAKTNFGHLEAAA
                     GMVGLAKTVLALHHGLLPAHLHLTEPNPLIDFDALGLRVVTAPEPWPRYSGTATAGVSA
                     FGFGGTNAHVTLAEY"
     CDS_motif       complement(23622..23666)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0004"
                     /evalue="4.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="RVR_RS06165"
                     /protein_end="514"
                     /protein_start="499"
                     /score="9.8"
                     /tool="antismash"
                     /translation="GSAKTNFGHLEAAAG"
     CDS_motif       complement(23727..23774)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0003"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="RVR_RS06165"
                     /protein_end="479"
                     /protein_start="463"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YVEAHGTGTALGDPIE"
     CDS_motif       complement(23958..23996)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0002"
                     /evalue="2.80E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="RVR_RS06165"
                     /protein_end="402"
                     /protein_start="389"
                     /score="13.9"
                     /tool="antismash"
                     /translation="FDASADGMVRGEG"
     CDS_motif       complement(24138..24185)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06165_0001"
                     /evalue="4.30E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="RVR_RS06165"
                     /protein_end="342"
                     /protein_start="326"
                     /score="21.7"
                     /tool="antismash"
                     /translation="GPSMAVDTACSSSLVA"
     aSDomain        complement(24966..25148)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS06165_ACP.1"
                     /evalue="6.00E-15"
                     /label="RVR_RS06165_ACP.1"
                     /locus_tag="RVR_RS06165"
                     /protein_end="66"
                     /protein_start="5"
                     /score="47.3"
                     /tool="antismash"
                     /translation="AWYGLDPSDIDDDRPFAELGLTSRDAVALSGELRALTGVPLAPTA
                     LWDATTLGRLLGALAE"
     gene            complement(25381..27246)
                     /locus_tag="RVR_RS06170"
                     /old_locus_tag="RVR_1748"
     CDS             complement(25381..27246)
                     /NRPS_PKS="Domain: CAL_domain (46-520). E-value: 3.7e-78.
                     Score: 254.5. Matches aSDomain:
                     nrpspksdomains_RVR_RS06170_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523425.1"
                     /locus_tag="RVR_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1748"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_202232878.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 1.8e-212, bitscore:
                     707.0, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-81, bitscore:
                     270.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTPPPARPVPLTESLRRWSAERGGQRAFTFVDYPDPDSPGRART
                     LTWRRLDEHARDIALRLRGRVGPGERAALMLPQGLGYVAAFLGCLYAGVIAVPLFGPDL
                     PGHADRLAAVLGDCEPRCVLTDAATAPAVDAFLAEHGIPPVPVLHVERTPGAEPPPRIP
                     WPTADPEDIAYLQYTSGSTRVPAGVMISHGNVVANAQQAIDAFAATPEDTTTVGWLPLF
                     HDMGLVLSVAAPVVGGFPSVLTDPVAFLEQPVRWLRLLSTYRGAISAAPNFAYDYCAAR
                     ITAEQAAGLRLDGVRALINGSEPVRPGTVGRFHAAFADAGLRPQAHCPSYGLAEATVFA
                     TTDPPTAPPRTLACDADALAEGRIVPAGAEEHVGAAEATGERTPAGAAEGGSEREAAGA
                     VEGRPAPVTLVGCGIPVGQVLRITDPRTGRPLPTGHVGEIRLRGPNIGLGYWKRADRSA
                     ESFAARITGEYGDWLRTGDLGALHDGQVYVTGRLKDLLVVDGRNHYPQDLEETVQAALP
                     VVRRDRLAVFAVPPARGARDADAAPDIVAVAEYRRGAGPTAQDRTAAEGAARAAVSARH
                     GVRLARLVLVPPGAVPRTSSGKVSRSACRDRYLTGSLAKEAAPGA"
     aSDomain        complement(25687..27108)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS06170_CAL_domain.1"
                     /evalue="3.70E-78"
                     /label="RVR_RS06170_CAL_domain.1"
                     /locus_tag="RVR_RS06170"
                     /protein_end="520"
                     /protein_start="46"
                     /score="254.5"
                     /specificity="Minowa: AHBA"
                     /tool="antismash"
                     /translation="TWRRLDEHARDIALRLRGRVGPGERAALMLPQGLGYVAAFLGCLY
                     AGVIAVPLFGPDLPGHADRLAAVLGDCEPRCVLTDAATAPAVDAFLAEHGIPPVPVLHV
                     ERTPGAEPPPRIPWPTADPEDIAYLQYTSGSTRVPAGVMISHGNVVANAQQAIDAFAAT
                     PEDTTTVGWLPLFHDMGLVLSVAAPVVGGFPSVLTDPVAFLEQPVRWLRLLSTYRGAIS
                     AAPNFAYDYCAARITAEQAAGLRLDGVRALINGSEPVRPGTVGRFHAAFADAGLRPQAH
                     CPSYGLAEATVFATTDPPTAPPRTLACDADALAEGRIVPAGAEEHVGAAEATGERTPAG
                     AAEGGSEREAAGAVEGRPAPVTLVGCGIPVGQVLRITDPRTGRPLPTGHVGEIRLRGPN
                     IGLGYWKRADRSAESFAARITGEYGDWLRTGDLGALHDGQVYVTGRLKDLLVVDGRNHY
                     PQDLEETVQAALPVVR"
     CDS_motif       complement(25864..25953)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06170_0002"
                     /evalue="1.20E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="RVR_RS06170"
                     /protein_end="461"
                     /protein_start="431"
                     /score="24.1"
                     /tool="antismash"
                     /translation="PTGHVGEIRLRGPNIGLGYWKRADRSAESF"
     CDS_motif       complement(26671..26730)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06170_0001"
                     /evalue="5.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="RVR_RS06170"
                     /protein_end="192"
                     /protein_start="172"
                     /score="25.1"
                     /tool="antismash"
                     /translation="AYLQYTSGSTRVPAGVMISH"
     gene            complement(27436..28983)
                     /locus_tag="RVR_RS06175"
                     /old_locus_tag="RVR_1749"
     CDS             complement(27436..28983)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140838.1"
                     /locus_tag="RVR_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1749"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_202232879.1"
                     /transl_table=11
                     /translation="MTRTAEFESRRARLLRGGPPEAVARLHARGRLTARERLDALLDEG
                     SFTEFDAFVQHRATAFGMDSRRPDGDGVVTGHGTVDGRQVAVFAQDATVFGGSMGEAFG
                     QKVAKVMDHAVKVGCPVIGLNDGGGARIQEGVVALAHYAELVHRNVRASGVVPQLSLVL
                     GPCAGGAAYSPALTDFTVMVRDTSHMFVTGPDVIRSVTGEVTTAEELGGAHTSGTVSGT
                     AHYVADDEADAFDFVRVLLSYLPANNRDAPPDYGLRADPSVTARDLQLDAIVPEDPGRA
                     YDMRDVLRRVVDDAELLEVQELFAPNIICAFARVEGSSVGVVANQPLHSAGALDIDASE
                     KAARFVRFCDAFGIPLLSFVDVPGYLSGVRLEHEGIVRRGAKLLYAYAEASVPTVTVVV
                     RKAYGGGYAVMGSKHLGADLNLAWPTARIAVMGAQGAVAILHRRALSEAEDPELLRKQL
                     VEEYENDFATPFQAAQRGYLDAVIMPHETRGRIVRGLRALRTKELALPQRRHGNIPL"
     gene            29303..30511
                     /locus_tag="RVR_RS06180"
                     /old_locus_tag="RVR_1750"
     CDS             29303..30511
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140840.1"
                     /locus_tag="RVR_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1750"
                     /product="PucR family transcriptional regulator"
                     /protein_id="WP_237404598.1"
                     /transl_table=11
                     /translation="MVRHGAVLAEEPFHRFSADLAEHLRPLTEDIRREVVNAILAGIPE
                     YARPTNAAYTTTITTGVELGLNLLLDRLTAPGIGAREVFDIYHAIGRGEAREGRTLDSF
                     QGALRIAARITWRTISTLADSDTLPRQELALLGEAALVHLDEIAAATSAGFAEAQAHLA
                     DEPRRRRLRLLDMLTDEQPPTAQAIATLAPAARWPVPSRIAVAVLDGHWEREESRPILP
                     PDLLADFDRKPVRVVVPDPEGPGRARAIEAALRGHRAALGPTVPLTEGARSLRWALDAL
                     GLARRSVLPSRGLVRCSDHLTTLLLFQDEDLVDALGTRHLDPLERMPRPYRDRLAETLL
                     SWLRCSRNASEVAVRLGIHPQTVRYRLRRLDDLFGDRLQDPDVCFEMELALRLRQMRPR
                     QAG"
     misc_feature    29329..29343
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.73"
                     /tool="antismash"
     misc_feature    30401..30403
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            30803..31747
                     /locus_tag="RVR_RS06185"
                     /old_locus_tag="RVR_1754"
     CDS             30803..31747
                     /EC_number="1.14.19.-"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta9_cd03505"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007264560.1"
                     /locus_tag="RVR_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1754"
                     /product="fatty acid desaturase"
                     /protein_id="WP_202232880.1"
                     /sec_met_domain="delta9_cd03505 (E-value: 2.2e-92,
                     bitscore: 309.7, seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASSAEAAPWGEPMRTSDRVVVGLFVGVPFAAVIASVAVLWGWG
                     IGWHDVVIGAVAYAVAVHGVTIGYHRLFTHRAFRAARPLKILLAVAGTLAVEGDVITWC
                     ADHRRHHQFADRPGDPHSPWRFGTSAAAVAKGMVWAHIGWTFTNEKTNQARYVPDLLAD
                     RDLVRVARWQPLVVAASFGLPAVAGGLWGPGGWDGRAALSAFFWAGLVRIGLLHHVTWS
                     INSICHVAGARPFRSRDRSGNVWWLAPLSGGESWHNLHHADPTSARHGVLPGQIDSSAR
                     LIRIFELLGWARAVRWPDRRRLAARAVRDGAEG"
     gene            32048..32563
                     /locus_tag="RVR_RS06190"
                     /old_locus_tag="RVR_1755"
     CDS             32048..32563
                     /EC_number="2.7.1.12"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046316 - gluconokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885038.1"
                     /locus_tag="RVR_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1755"
                     /product="gluconokinase"
                     /protein_id="WP_202232881.1"
                     /transl_table=11
                     /translation="MTARPAAPLPLVVIMGVSGSGKTTIGGLLAARLGVPYAEADDFHP
                     AANLAKMASGRPLDDADRAPWLDTIAEWLAGRGLRGGVVSCSALRRRYRDRLREAAPGL
                     FFAHLDGTPELIAARLAGRTHHFMPPALLASQFEALEPLEPDESGTAVPIDGDAEPTVE
                     RILAALPA"
     gene            complement(32571..33908)
                     /locus_tag="RVR_RS06195"
                     /old_locus_tag="RVR_1756"
     CDS             complement(32571..33908)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001374.1"
                     /locus_tag="RVR_RS06195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1756"
                     /product="glucarate dehydratase family protein"
                     /protein_id="WP_202232882.1"
                     /transl_table=11
                     /translation="MGERDSYIQTAGAPSGAASATIAEVRLTPILIADPPLLNTQGVHQ
                     PYTPRLIVEVVTSDGTTGVGETYGDSGYLRLAAPLAQALPGHRLDDLNGLFTLAERVCG
                     DPGEVSDSVTSSGLRGVQTADKLRLSVISGFEVACLDALGKVVGLPVHALLGGKVRDAV
                     DYSAYLFYRLAEHPQGAGEADDWGAALDPAGVVAQARRFADAYGFGSFKLKGGVFPPDQ
                     EIAAVRALAQAFPGKPLRLDPNGAWSVETSLEVARELGDVLEYLEDPASSTDRMARVAA
                     QTSVPLATNMCVTTFPEIPEAFARGAVQVVLSDHHYWGGLRNTQHLAAICRTFGVGLSM
                     HSNTHLGISLAAMTHVAATVPNLDYACDSHYPWQSEDVITERHVFTGGRLAVSDTPGLG
                     VELDRDALARLHRRWQDDDGTMRDRDDAAAMRKADPEWRMPSVPRW"
     misc_feature    33880..33898
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    33899..33914
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(34027..34042)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.51"
                     /tool="antismash"
     gene            34051..35112
                     /locus_tag="RVR_RS06200"
                     /old_locus_tag="RVR_1757"
     CDS             34051..35112
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018532841.1"
                     /locus_tag="RVR_RS06200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1757"
                     /product="phosphotransferase family protein"
                     /protein_id="WP_202232883.1"
                     /sec_met_domain="APH (E-value: 1.7e-49, bitscore: 167.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASANPPGLDLDRLRRHLDRELPGLVRGGLRADLLEGGRSNLTY
                     RVTDGAGTWVVRRPPLGHVLATAHDMGREHRVISALADTPVPVPRTLLRCDDPEVVGAP
                     FYVMEFVPGTPYRSEDQLREIGPERTRAAVHTLVDTLVDLHAVDPAAVGLADFGRPEGF
                     LDRQLRRWGKQLDASRSRELPGVDELHAALGRSLPDSPAPAIVHGDYRLDNVLIDAGGR
                     LTAVLDWEMSTLGDPLTDLGLLVMYTEQRSSDLLSAPATGGAPGHPGAREIVARYAERS
                     GRDVTAVDWYTAFAYFKLAVILEGIHYRWTLGQTVGAGFDRIGDVVPVFIDRGLNTLRR
                     SGAGHLPTTRDED"
     gene            35119..36333
                     /locus_tag="RVR_RS06205"
                     /old_locus_tag="RVR_1758"
     CDS             35119..36333
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141665.1"
                     /locus_tag="RVR_RS06205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1758"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_202232884.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.8e-13, bitscore:
                     47.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.2e-21, bitscore:
                     73.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.7e-36, bitscore:
                     124.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFGYDTRTEELRARLSAFLDEHVLPAEPVFAQQREQAVGDDRWT
                     APPIVELLKAEARSQGLWNLFLPGEHGAGLTNLQYAPLAELTGRSPHLAPPALNCAAPD
                     TGNMEVLAEFGTPAQRKEWLDPLLAGEIRSAFAMTEPEVASSDATNIETRIERDGDSYV
                     INGRKWYISGAMNPKCAVLIVMGKTDPTAERHRQQSQVLVPRDTPGVDVRRGMRVFGYD
                     DGDHGGHAEIVFRDVRVPVANLVGEEGGGFAIAQARLGPGRIHHCMRLIGMAERALELM
                     CRRANARTAFGKPLAAQGVVQEWIAEARVEIEQLRLLVLKTAWLMDTVGNQGAHTEIQA
                     IKIATPAAVQRIVDRAIQLHGAGGVSQDFPLAELWAAVRTLRLADGPDEVHKRSLARRE
                     LRRYA"
     gene            complement(36471..37454)
                     /locus_tag="RVR_RS06210"
                     /old_locus_tag="RVR_1763"
     CDS             complement(36471..37454)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0003960 - NADPH:quinone reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_function="GO:0070402 - NADPH binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (15-325). E-value: 2.6e-61.
                     Score: 199.4. Matches aSDomain:
                     nrpspksdomains_RVR_RS06210_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627472.1"
                     /locus_tag="RVR_RS06210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1763"
                     /product="NADPH:quinone oxidoreductase family protein"
                     /protein_id="WP_202232885.1"
                     /sec_met_domain="ADH_N (E-value: 2.8e-10, bitscore: 38.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.5e-30, bitscore:
                     103.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAWRVHHNGEPREAMRLDEIPTPAPGPGEVLLRVRAACVNFPDA
                     LLCRGQYQVRPPLPFTPGVELCGEVVRAGEGVAGLTPGDRVISPVALPAGAYAEYAVVP
                     AAGVLPAPEALDDAEAAALHIGYQTGWFGLHRRAALRPGETLLVHAAAGGVGSAAVQLG
                     KAAGATVIGVVGGPEKAGAAREAGADVVVDRHREDFVAVVKEATGGRGADVVYDPVGGD
                     AYTRSTKCIAFEGRIVVVGFTSGTIPAPGLNHALVKNYTILGLHWGLYNTQDPAAVRRA
                     HDELTDLAAKGAVKPLVSERLPLTAAADAVQRVSDGTTVGRLVVLP"
     aSDomain        complement(36480..37409)
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS06210_PKS_ER.1"
                     /evalue="2.60E-61"
                     /label="RVR_RS06210_PKS_ER.1"
                     /locus_tag="RVR_RS06210"
                     /protein_end="325"
                     /protein_start="15"
                     /score="199.4"
                     /tool="antismash"
                     /translation="MRLDEIPTPAPGPGEVLLRVRAACVNFPDALLCRGQYQVRPPLPF
                     TPGVELCGEVVRAGEGVAGLTPGDRVISPVALPAGAYAEYAVVPAAGVLPAPEALDDAE
                     AAALHIGYQTGWFGLHRRAALRPGETLLVHAAAGGVGSAAVQLGKAAGATVIGVVGGPE
                     KAGAAREAGADVVVDRHREDFVAVVKEATGGRGADVVYDPVGGDAYTRSTKCIAFEGRI
                     VVVGFTSGTIPAPGLNHALVKNYTILGLHWGLYNTQDPAAVRRAHDELTDLAAKGAVKP
                     LVSERLPLTAAADAVQRVSDGTTVGRLVV"
     CDS_motif       complement(36969..37028)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06210_0001"
                     /evalue="7.20E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="RVR_RS06210"
                     /protein_end="162"
                     /protein_start="142"
                     /score="24.8"
                     /tool="antismash"
                     /translation="GETLLVHAAAGGVGSAAVQL"
     gene            complement(37451..38146)
                     /locus_tag="RVR_RS06215"
                     /old_locus_tag="RVR_1761"
     CDS             complement(37451..38146)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544058.1"
                     /locus_tag="RVR_RS06215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1761"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_202232886.1"
                     /transl_table=11
                     /translation="MARKATSGSSGGGGTGPGTARAGATAPGTTAPGATAAVPERLLAE
                     ATRLFAERGYDRTSVQEIVEAAGVTKGALYHYFGSKDDLLHEIYGRVLRLQTERLDAIA
                     ARPVPVTERIAEAAADVVVTSIQNLDDTKIFFRSIHQLGPEKQKAVRAERRRYHETFRA
                     LIEEGQRDGLLRPEPRPDLVVDYFFGSVHHLGTWYHADGPLTAEQVAAEFSDLLLHSLR
                     PPATPGDPT"
     gene            complement(38204..39943)
                     /locus_tag="RVR_RS06220"
                     /old_locus_tag="RVR_1764"
     CDS             complement(38204..39943)
                     /NRPS_PKS="Domain: AMP-binding (32-483). E-value: 7.7e-99.
                     Score: 323.0. Matches aSDomain:
                     nrpspksdomains_RVR_RS06220_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087843.1"
                     /locus_tag="RVR_RS06220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1764"
                     /product="AMP-binding protein"
                     /protein_id="WP_202232887.1"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-105, bitscore:
                     350.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSADQPWLKHFTQEQRAASEHPPSVLHTFLAVAGRTPERPALR
                     YFDGTLAYGELDALSDGLARHLAERGFAPGDRLAVMLQNVPQFVIGLLAAWKAGGVVIP
                     VNPMYKSGELAHILHDAGAAAILCSRTAWEAYVRDTVADSPVRIALTADEHDLQTRDDA
                     RVLGQRPRPGTSELPASDGPAPEGSTPAGTASDGPGVPPDVLAVARAHAGPSPVRSAAD
                     LPAADDTALVSYTSGTSGHPKGALNTHGNISFNAHRQVRLQQLPDDAVVFVLAPLFHIT
                     GMVCQLAAALAGGHSVALAYRFEPGVVLDAFREHRPAFTVGPSTAFMALLARPDAAPGD
                     FASFRHIASGGAPLPPAVVESFRTRSGGRYLANGYGLTECTAPCASVPPGLEAPVDPES
                     GTLAVGVPGPGTMVRILDDTGAEVPFGQQGEIAVSGPMVVPGYWNKPEETAAGLPGGEL
                     RTGDVGFMDEDGWLYVVDRKKDMINASGFKVWPREVEDVLYTHPAVREAAVVGVPDAYR
                     GESVKAYVSLQPGAAVEPEELVAYCRERLAAFKYPRQVEVRVELPKTTTGKILRRELRA
                     AAG"
     aSDomain        complement(38495..39847)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_RS06220_AMP-binding.1"
                     /evalue="7.70E-99"
                     /label="RVR_RS06220_AMP-binding.1"
                     /locus_tag="RVR_RS06220"
                     /protein_end="483"
                     /protein_start="32"
                     /score="323.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AVAGRTPERPALRYFDGTLAYGELDALSDGLARHLAERGFAPGDR
                     LAVMLQNVPQFVIGLLAAWKAGGVVIPVNPMYKSGELAHILHDAGAAAILCSRTAWEAY
                     VRDTVADSPVRIALTADEHDLQTRDDARVLGQRPRPGTSELPASDGPAPEGSTPAGTAS
                     DGPGVPPDVLAVARAHAGPSPVRSAADLPAADDTALVSYTSGTSGHPKGALNTHGNISF
                     NAHRQVRLQQLPDDAVVFVLAPLFHITGMVCQLAAALAGGHSVALAYRFEPGVVLDAFR
                     EHRPAFTVGPSTAFMALLARPDAAPGDFASFRHIASGGAPLPPAVVESFRTRSGGRYLA
                     NGYGLTECTAPCASVPPGLEAPVDPESGTLAVGVPGPGTMVRILDDTGAEVPFGQQGEI
                     AVSGPMVVPGYWNKPEETAAGLPGGELRTGDVGFMDEDGWLYVVDRKKDMIN"
     CDS_motif       complement(38591..38674)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06220_0002"
                     /evalue="9.50E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="RVR_RS06220"
                     /protein_end="451"
                     /protein_start="423"
                     /score="27.6"
                     /tool="antismash"
                     /translation="PFGQQGEIAVSGPMVVPGYWNKPEETAA"
     CDS_motif       complement(39197..39256)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_RS06220_0001"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="RVR_RS06220"
                     /protein_end="249"
                     /protein_start="229"
                     /score="17.2"
                     /tool="antismash"
                     /translation="ALVSYTSGTSGHPKGALNTH"
     gene            complement(39940..40758)
                     /locus_tag="RVR_RS06225"
                     /old_locus_tag="RVR_1765"
     CDS             complement(39940..40758)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059594.1"
                     /locus_tag="RVR_RS06225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1765"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_237405248.1"
                     /transl_table=11
                     /translation="MEALSGARVVVTGAGGGIGAALARRFAAEGARVAVNDLDADAARA
                     TAAEIDAAVVPGDASGVVPAARTALGGTIDVFCANAGVGTGGGPEADEDAWELAWDVNV
                     MSHVRAARDLLPEWLERGSGRFVSTVSAAGLLTMIGAAPYSVTKHGALAFAEWLSLTYR
                     HRGVRAHAVCPQGVRTAMLSTTGPAGDLVLAPTAIEPEDVADAVIEGIAAERFLILPHP
                     EVAGYYAARAAEPERWLGGMNKLQRQYEQQLAAAEERPADAAGAERGGRA"
     gene            complement(41032..43806)
                     /locus_tag="RVR_RS06230"
                     /old_locus_tag="RVR_1767"
     CDS             complement(41032..43806)
                     /EC_number="3.5.1.-"
                     /GO_function="GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671750.1"
                     /locus_tag="RVR_RS06230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1767"
                     /product="penicillin acylase family protein"
                     /protein_id="WP_202232889.1"
                     /transl_table=11
                     /translation="MPLRTPRRIGTRVGRRIGTLRTAAAAALLALGATLLAPGAMAAHA
                     ADPTTDYCGGQCSDILPPGENGNATLADILANKAFGTRPAHTTDQLGPYSSLATGYQNL
                     TDATLSNFFNSSSFGVPSNQVASVVSPRSDVTITRDKATGVPHIKGTTRDGTEFGAGYA
                     AAQDRLWLMDLFRHVGRGELSSFAGGAAANRGLEQEFWQQAPYTEADLQAQVDWLSNNS
                     GDRGRQALADAQDYIDGINAYITAAKSGRYFPGEYDLTGHVNAITNAGDIEPFQLTDLI
                     ALASVIGALFGTGGGGEVQSALSLLAAQQKYGVQDGTNVWESFRERDDPEATSTVHDGS
                     SFPYAGKPASAQGEALPDPGSVVPEPLVYDATGGATQSTTKSPGVLPSNMFSDPRKGMS
                     NALVVSGAHTASGHPVAVFGPQTGYFAPQLLMLQELQGPGISARGASFAGLGMYVELGR
                     GQDYAWSATSASQDVTDTYAVQLCQDDTHYILHGSCVPMEKLERTNSWTPTLADSTPAG
                     SYRMQVWRTAYGPVIYRATVGGKPVAYTQLRSSYMHEADSIIGFQELNDPGFVHDAASF
                     QKAAQDINYTFNWFYADSRQTAYYNSGTNPVRAAGVDASFPVWGTGAYDWQGWDPTHNT
                     ATYTPPSQHPQSVDQDYYISWNNKQAPGYTSAGFGNGSVHRADLLEDRVKALVQAGGVT
                     RASLVKAMSSASLTDLRGEDVLPELLQVIKSAPVTDSQEAAAVQQLTTWLADGTKRTET
                     SAGSHTYADADAVRTMDAWWPLLVQGEFQTGLGTDLYNALAADLTIDESPSAGHGPTGS
                     HAGSSFQYGWWSYVDKDLRKVLGQSVQGPLAHTYCGGGQLSACRNILLSTLKQAAATPA
                     TTVYPGDDGGCAAGDQWCADSIVQRPLGGITDDRISWQNRPTYQQVVEFPSHR"
     misc_feature    complement(43906..43926)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            complement(43963..44706)
                     /locus_tag="RVR_RS06235"
                     /old_locus_tag="RVR_1768"
     CDS             complement(43963..44706)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458887.1"
                     /locus_tag="RVR_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RVR_1768"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_202232890.1"
                     /transl_table=11
                     /translation="MSLRHHEIAESGHRILNPITDEKLMLLGEVCRLKEGQRQLDLACG
                     KGEMLTRWAERYGTGGVGVDLSEVFLTAARLRAAELGVAERVDFVRGDAGAYEAEPAAF
                     DVVSCVGATWIGGGLGGTVDLLRRALRPGGLMLVGEPYLTEPAPKEAFEAMGFEPEDFT
                     SLVGTLDRFEAAGTELVEMVLADGDSWDRYVAEQWFAISDWLRAVPADHRDAADMREFL
                     AHSRRTHLEYQRRYLGWGVFVLRAV"
ORIGIN
        1 gtcggcgagg ccgccggtgg tgggcgcgta ggaccacgcg ttgtcgttga cgacgatgac
       61 gagcggccgg tccttcgccg ccgcgatgtt gttgagcgcc tcccaggcca tgccgccggt
      121 cagcgcgccg tcgccgatga ccgcgaccac gctgtcgtcc ctccccagca gccggttggc
      181 cgcggccagg ccgtcggccc agcccaggac ggtggaggcg tgcgagttct cgatcacgtc
      241 gtgcggggac tcggcgcgcg acgggtagcc cgacaggccg ccccgcgccc gcagccggcg
      301 gaagtcctga cggccggtca ggagcttgtg cacgtaggtc tggtggccgg tgtcgaagag
      361 gatcctgtcg ttcggcgagt cgtacacccg gtggagggcg atggtcagct ccaccacccc
      421 caggttcggc ccgaggtggc cgccggtccg cgcgaccgcg tcgatgagga acgccctgat
      481 ctcgccggcg agttgcgtga gctgatcgga gtcgagcccg tccaggtccc ggggatccct
      541 gatgtgcgtc agcagtgaca ccgtgcctcc ttcgcgaatg ggccggtcgg cgccgccgtc
      601 cggccgatgg tggttccgcc ccgtggcgcc cgccggttca ggccgcgggt ccttccggcg
      661 gtacggggcg gaccagccgc ccgaccgcgc tcctggcgtg ggcggccgcc gcctgccgcg
      721 tcggcgcggg ggccagcccg agcagccgcc ggcggtgcgg ttcgcccagc agcagggcga
      781 acagggcctc ggctgtctcg gggtcgggcg gggtgaggcg gtcggcgagc gcggcgacgt
      841 agccgcgcgg cccgtcgtcg tagaagcggc gggcgaggtc cgggaagcgg tgggcttcgg
      901 tgatcatcag ccggtgcagg ccgacggcct cgtcgccgtg gagcgcgaag acgatcttcg
      961 ccgcgaggtc caccaggccg tcctcgcgca cgggctgttc gagggcgcgc tcccggagcc
     1021 gttcgaccgc cgcgaggaag atctcggtcc ggtccccgac gtaggcgtag atggtgcgct
     1081 tggtcacgtg tgcccgcgcg gcgatgtcgt cgagcgtgac ctgctcgaac ccgccggcca
     1141 cgaacaggcg gaccgcggcg tcgaggatct cgtcccggcg ctgggcgcgc tcggccgcgg
     1201 tcgggcggcc gcgcttgcgc gccgtctgcg gcgcggcggc gccctcgttg tccctcgcag
     1261 tcatcgcgca ccctccgtgg tcgacagcgt ccgggccccg atcctataat gaaccgaagc
     1321 tcgtatcatt aatgaggtga ccgccccgca cccgcggggc ggaacgacgg cccccgcggt
     1381 ccggccggac cggccggcag gcgggcgcgg tccgtcaggg tgagaaggag atctcgtatg
     1441 cccccgacta ccagggcctc agcggccggg aacccgccgg accggggcgc tcgcgcacag
     1501 ggcggcggga ggtccggacg ccgcagggcg gccgcgggga cggccgggcc cggggcgccc
     1561 gcggcggagg gggaggtccg cgcgggttcg ggcggggaag cccccgcgga cgcggaggcc
     1621 ggccccggta cgggcggaga agcgctcgcg gacgcggaac tgctcgcctt ctaccggcag
     1681 atggtgctgg tccgacggtt cgaggagcgt gcggcccgcg cctacacgga ggcgaaggtc
     1741 ggcggctact gccacctgaa cctcggcgag gaggccaccg tcgccgggct gatggccgcg
     1801 gcgcggtcgg aggactacgt cttcaccaac taccgggagc acggctacgc cctcgcccgg
     1861 ggcatcgcgc cggaacgggt catggccgag ctgtacgggc ggaccgacgg cgtctcgaag
     1921 ggctggggcg ggtcgatgca catgttcgac gtcgcctcgc ggttcatggg cggctacggg
     1981 atcgtcggcg gccaggtccc gctggccacc ggggcggccc tggccgtcga ctaccgcggc
     2041 ggcaccgagg ccgtggtctg cctgatgggc gacggcacga cgaacatcgg cgccttccac
     2101 gagtcgctga acatcgccgc gctgtggggg ctgcccgtcg tgtacgtggt cgtcaacaac
     2161 gggctgggca tgggcaccac cgtcgagcag tcctccgccg agcccgagct gcacaagagg
     2221 gcggcgtcgt accggatggc ctccgcccgc gtggacggca acgacccggt ggccgtcttc
     2281 cgggccgccc gcaccgcgct ggacagcgcc cgggcggggc ggccgtacct gctggagacc
     2341 gtctcgggac gcctcaaggg gcactccgtg gtcgatcccg cccggtaccg cacccgcgag
     2401 gaggccgagg cgctgcgcgc ggccgatccg atcgccgcct acgccgtacg gctgcaccgc
     2461 cagggcgtgt tgaccgacga gctcatcgag cggatcgacg ccgaggccac cgccgcggtg
     2521 accgccgccg cggcgttcgc cgacgccagc ccgcacccgg acgtgtccac cctcttcgac
     2581 tacacctacg ccaccccggt gccgaacgac tcccggcgcc tgccgggcga ggcgctgttc
     2641 ccggcgccgc cgcgcccggt gggcgcctcg cccgcggggg tgccggcatg agcgtgatca
     2701 gctaccgcca ggccctgcac gccgccctgc acgacgagat gctgcgcgac gagcgggtgt
     2761 tcctgatcgg cgaggagatc ggccggttcg aggggtcgta caagatcacc gcgggcatgc
     2821 tcgacgcctt cggtccgcgg cgggtgcggg acaccccgat cgccgaggag gggttcaccg
     2881 gggcggcgat cggcgcggcc atggtggggc tgcggccggt cgtggagatc atgacgatca
     2941 acttctcgct gctggcgctg gaccagatcg tgaaccacgc cgcgaaggtc tacggcatgt
     3001 tcggcggcca ggcgcgcgtc ccgctggtga tccgcacccc cggcggagga gggcagcaac
     3061 ttggcgccac gcactcgcag aacatcgagc tgtactacgc cttcgtcccg ggcatgaagg
     3121 tggtcgcgcc gtcgagcccg gcggacgcga aggcgctcat gctggcggcg atccgcgacg
     3181 acgaccccgt cctggtgctg gagaacctcg ccctctacaa caccaccggc gaggtccccg
     3241 acgacctcgg gcccgcgccg atcggccggg ccgccgtcac ccgggagggc gccgacatca
     3301 ccgtggtcgc gtactcgcgg atggccgccg tggccctcca ggtggccgag cgcctcgccg
     3361 gtgaggggat cgacgtcgag gtggtcgacc tgcgcagcct ccgcccgctg gaccgggagt
     3421 cgatcgtcgc gtccgtgcgg aagaccgggt gcgcggtcgt gctggaggac gactggctca
     3481 cctacggcat cggtgccgag gtcgccgcca cgatcggcga cggggcgttc gactggctcg
     3541 acgcccccgt ccggcgggtc gccatggccg aggtcccgct gccgtacgcg aagaccctgg
     3601 agaccgcggc cctgccctcg gccgacgacg cggccgccgc catccgcgag acgctcgacg
     3661 ccgtcgcacg gcgccgctga gcccacggaa cgacagaaga gacgccatga tcgacatcct
     3721 catgccccgc ctgtccgaca ccatgacgca gggggtcgtc gccgcctggc tcaaacagcc
     3781 cggcgacacc gtgagcccgg gcgacgtgct ggtcgagatc gagaccgaca aggccctcat
     3841 ggaacacgag gcgtacgacg ccggcacgct ggccgagatc ctcgtccccg aaggggggag
     3901 cgcgcccatc ggcgcaccca tcgcccggct ggacgacggt gcgtccgtgg cggccggtgc
     3961 gggggccgac gccatgggcg acggtgcccg ggccggtgcc ggtaccggta ccggggcccc
     4021 gggtgatgcc gccggtggtc ccgtcggtgg tgccggtagc gtcaccggca ccggcaccgg
     4081 cggcagcggc ggcagcggga gcggcggcac gccaggcgcc gcgggggcct ccgggccggg
     4141 gccggccgcg gccgaggatc acacggaagc cgggtcgccg tcagggccgc ccacgaccgc
     4201 gcccgatctg ccggagcgcc gggcggcgac gccactggtg cgccggctgg cgcgggagcg
     4261 cgacatcgac ctcgccacgg tcgccggcac cggtccgggc ggccggatcg tgcgcgccga
     4321 catcgacgcg ctcgacacgc tcgccgcgct cgccgcgccg gaagcgccgg gcgggcaggg
     4381 tgcggtggac gccgtgaacg ccctggacgc ggcggccgcc ccgggtaccg cgaagacgcc
     4441 ggacgggcgg gaaccgcggc cggtgccgtt cgacccgatc cgccgggcga tcgccgcacg
     4501 gctgacggag agcggcacca ccgtccccac cttcaccgcg accgcctccg cggacgtcgg
     4561 cgacctgctc gccctgcgcg ggcggatcaa cgcctcccgc gccgaggacg gggtgaaggt
     4621 cagcgtgaac gacctcctcg tccgcgcggt cgcgctcgcg ctgcgcgggc accccggcgt
     4681 caacgcgtcg tactccccgg acggtcaggg gcagacgctc ctgcacgggc gggtgcacgt
     4741 cggcgtcgcc gtcgcgtcac ccgccggcct ggtcgtcccc gtcgtccgcg acgcggaccg
     4801 cgcgtcggtc accgcgatcg ccgccgcgac ccgggacctt gtcgcgaagg ccgcggaacg
     4861 gcggctggcc gccgcggaca tgggcgacgg gacgttcacg gtcagcaacc tcgggatgta
     4921 cggcgtggag cacttcaccg cgatcatcaa ccctccccag ggcgcgatcc tcgccgtggg
     4981 cgccgccggc gacgaactcg ccctcgccgg cggtgaggtg gtgacgcgca agcggctgcg
     5041 gtacacgctc acggccgacc accgcgtcat cgacggggcc ctggcggcgc agttcctcaa
     5101 gacgctcacg gagctgctgg agaaccccct gcggatcgtc gcctgagcgg gcgccaccgc
     5161 cggtacgcac cagcgacgtg tcaccgccgg gaggtggcgg tgacacgtcg ccgtcggatg
     5221 gaggcggcgg gcgccgcccc ccgtcagaag ctgacgaccg tggcctgttc gagggtgaag
     5281 cgcacgaact cgtcgcgggc gacgcgcagg cgcaggccgc gcccggtgag caggtcctcg
     5341 accccgtcgg cgcgggcgga gttgacgcac gcccccacca cgacgcccgc cgcgaccagt
     5401 tcgtcgatct gccggttgaa ggtcaggacg gccgccgagc cgccctcctc cccgagccgg
     5461 cgctgggcgg gcccgaagca gaagacctcg acctcgctcc cccgctcctg tgcgacctcg
     5521 tggatgcgct gggccacccg cgttccggtg gccagcgcgt catcgtcgtc gtggaacaca
     5581 tgaatgaccg tcttgggcat cgcgcactct ccgctcgtcc actgcctcca gggcactgcg
     5641 gagcctagtg aacttctcaa ccaacgagac gtcttgtctc atcatgcgaa cggcgtgacg
     5701 ctgggagggc cggggcgccg ggcaccgggc ggcggcgccc cgggccggac ggaggctcag
     5761 gaggcgatgt agaggctggg actgtcgacc tcggggctgg cccagtagta gccgtcgggg
     5821 aaggtgatcc cggtgaccgc ggccgtgatg tacgtccccg cgccgtgcgg cgtgtcggtg
     5881 gtctggccgc ccaggttggt gctgtacgag tagcgcaccg tgctccgggc caccacggag
     5941 ctgttcttca ccagcgccac ctggaccgcg atggtgttga ccaggttgtt gcactggacg
     6001 ctgccgatgg cctccacccc gccgcccggg tacgcgcccc cgtagtagcg cagcgggtcg
     6061 ctggcggtga gggtgcaggt gatcgtgtag tacggcgcgg tggtcgaggt gtgggtgaag
     6121 ctggtcgtcg ccaccgccgg ggacaccacc gtggcgggcg ccgcgtggga ggcggacagg
     6181 tacccggcgg ccgaccggtc ggcgttcggg gccgcggcgc ccgcggcacc ggcggcgccc
     6241 acggtggtcg cgagggccag cgcggccccc gtcagcagcc gcgcggtacg gcggccggat
     6301 ctctttcggc cgtgttcctg ggacatcgga gtctccctgt gtcgtcggtg aggtgccgga
     6361 cgggcgcggg caggcgcgag cgcgcccggg acgtgccgtc cgggtgtacg gggcttgctt
     6421 cgtggtggtg ctcgcgtgcc gtgccgcgcc gtgccgcgcc gcgtgctgtg ccgtacgccg
     6481 tgccgtgccg tacgccgtgc gcgggccggt gcccgccgcg gcgcgccggc gtggtgccgt
     6541 cgtgcacggc ggcgccccgg ccgtccgccg ccccgtggcg ggcggggcgc gccgcgccgt
     6601 ggtcacgtca cggccgggca ccgggccgaa ccgccgcggc gaacgcggcg ggaggaacgt
     6661 gtggtgtggc tcagcatcac cggaagccca cactccgtca atgagcgccg gagaagaggc
     6721 gagataccac cataagggag gctggccggt ccgctacggt cccggcgccc catccggcca
     6781 ccccggacgg ggcaccccgg cccggccgcc cggcggcacc gccgggacca ccgcccccgc
     6841 ggacgtgggc gtacgcgcca gggcgccaca cgcccgggca cgctccccgc acggcccgag
     6901 ggctcggctc ctccgccggc ttccgcccgg ccgtcctgaa cacggcgtcc gccgggccgt
     6961 gttcgcgcca ccggccggcc ccgtacgggc ggcggcccgg ccaccccggg aacgccggcc
     7021 ggagcggccc gcttccgcgt gaccggcgca ctcccccgga cacgggaagc cgccttccgg
     7081 caattttcgg actccgtatg cttttcccgc ccatcagacc gtatggacac ccgcgaaccc
     7141 ctacactccg gaccccgccg gaccacgcgc cgcccgaccc gccacgcgcc gcccgacccg
     7201 accccgtacc ggccgcgccg tacgccaccg accggcccca ccggatgtgc ggcatcaccg
     7261 ggcggggata caccgcgcgc atattctcgg catgatcggg tcggcggtgg gaaagcggcg
     7321 gctcggaggt tgataatcat gggaccgttg ctcctcgttc ttctgctggc tctgatcctc
     7381 ttcggtgcgg gattcgcgct gaagattctc tggtgggtcg ccgtggtcgt gctggtggtc
     7441 tggctgctgg gcttcgtggt ccgctccacg cactccggcg gtgggcgtag ccgctggtac
     7501 cgctggtgac gcggcgagtg cacgccgtat cgccgtattg acgtcgccgc cgggggaata
     7561 catcccgcat tcggggaaag gcgccgtgaa gtcggggcgt gtgatcgcgt gaccgtttcc
     7621 ccggtggcgc cgagcgcatc cccttcccgg atttctgcgg gacctgcgcg gcaggtacat
     7681 ccgcagcgcg agaaaaagga gttgtgatga gcaccgatga caagaccaag gccaaggtcg
     7741 agcagggcaa gggcaagctc aaggagaccg ccggccgcgc ggtcggcaac gagcggctgg
     7801 aggccgaggg ccgcgcggag caggcgaagg gcgatgtccg cgccgcgggc gagaaggcca
     7861 aggacgccgc caaggacgct ttcgggaact gaccccgtcc tcggtccgcc ccggacacga
     7921 cggcggcggc ccaccgcgat cgacgcggtg ggccgccgcc gtcgtgtcac acccgcacga
     7981 cccggcggag gccggggacg tcagccgtcg cacccgacca gtccggcgag tgccgcgtcg
     8041 aggatcggct gccggtactc cggggtgccg gcgatcttcg cgacggccac cacgcgatcg
     8101 aggatctggt cgaggtcgac gcgcggcgcg ccgaggaggc cctgcgtcga ccggatcagc
     8161 gtcacggacc acgtccggca gatgccgacg ctcggaccgc ccgagcacga gatgcgggag
     8221 gcgtacacga ggctcggttg gctggcggcg aagaccgaac gggtgaagct gctcgcgctg
     8281 gtgaccgcgg tcgtcttccg cgagcccggg ctcctcgcga aggccgtgac caccctcgac
     8341 gtgctgtccg gcggccgggc ggtcctcggc atcggcgcgg cggcgcacgc ggacacgcac
     8401 gcggacgcgg ccggcccttc ccgccggtcg ccgagcggat cgagcggctc aggaggcgct
     8461 gcgcgtcgtc cggcacatgt ggagtggtta ggagggcccg ttcgacggcc ggcactaccg
     8521 cccggcccgt acgcccaact cccggcaggc gctgtccctc cgcacccgac gatcctggtc
     8581 ggaggcgagg gcgggaggaa gacgctgaag cgcgtcgccc gccacgccgg cgcgtgcacc
     8641 atcggcgtgt acgacctcga cgcgacgccc gccaactgga cgtcttccgc cggcactgcg
     8701 ccgacgaggg ccgcgatgac gaccggatgg ataagacggc agggcatcgc ttcgacctgg
     8761 ggaggaacgg cgagacgtca acaggacgtc gagcacctgc acgcggtcgc cgaagtggca
     8821 tcacccagcc ccacggcccc ctgctccggg tcggcgaacc cggtcggctc gacccgttcg
     8881 gcgagcgggt cgtccccgcc gtcgcgacgt tccggccgac ggtcccgacg cggaaaccca
     8941 tgccggatgc ccgactggcc cgggtgagcg aactgcgagc gaccgagacg tcgtgcggtc
     9001 ggagagcggc cgtcgcctcg ccggtcccgg cataccgccg cgcatggatg acgggcttcc
     9061 cgcgcgtgct cctacgtcgc gcgcgtgatg cttcgcgggc agccggtgcc ggcgcgggcg
     9121 cgttgtcctc ggcgttggga ctcggcattg gatgatcgcg gtatgcgtac ccgaccggta
     9181 gtggtcttcg atggggactg tgccttctgc acggcctcgg ttcagttcgg cgagcggtgg
     9241 ctgcggcccc gttgtgattt cacgccgtgg cagcgcgcgg atctacggtc actggggctc
     9301 gagcagcagc gagctgagta cgaagtgctc tgggtgacgc ccgcaggcgt ggtgtacgga
     9361 ggcgtccagg ccgtcgcgca gctgttgctc agtttcggca acaccgtcgg cggcaacacc
     9421 gtgggcggtg gcaacacgat cggcggtggc aacaccgtcg ggggtggcaa caccgtcggg
     9481 ggcagcaccg tcggcggcaa tacggccggc aacaccgctg gcaacaccgg cggcgaccac
     9541 gggaagcctc cgcacgagga gaagccgccg cagcacggca agccccctta cgacgagaag
     9601 ccctcctacg gcgacacccc tccctctgag ggcaagccca cgtacggcga caacccgacg
     9661 tacggcgaca acccctcgta cggagacacg ccgcagcagt cggacgatga ctacccctgg
     9721 gcgcagaagg cgaaggagca ggaacaggag agctaggccc aggagcactg atgcatcaac
     9781 ccgtcctggc ccggccgacg ctgcgacgcg tctgccgggc cgggcctcct ggctctccag
     9841 gtacggggaa gttcagcgga acgttgtgag aggagggccg ggatgacaac gactggccca
     9901 gaaggcgtac tgagcggggg ccggccggtg gacgtgaaag cgccggacgc cgcctcgtcg
     9961 cgcggccacg gcactgtgcc caccgcgctg ccggaccgac gaggagacaa cccacccgga
    10021 gggccggacg cgcctgccgc cctgccgcct gtactgcgga aggcgaccag gagcatctcc
    10081 gtcatgctgg tgtgcttcgc tctcctgcac ctgttcttcc ttttcctgca cgtcgcgcca
    10141 gagaaccaga tctcccggcg ctacgccggg cagatccaga gctgggtctt cccgttcttc
    10201 gagcagaact ggcgcctgtt cgcccccgac cccgagtcgg ccgtccccca gatctcggtc
    10261 cgcacggccc acacctccgc agacggtcac taccaggtca gcgcctggtt cgacctcaca
    10321 gcgatcgaca acgcaggcgt caggcacaac cccttcccga gccacaccac gcagaacatg
    10381 ctccgcaggg catggaccgg ctacctcgac tcccacagca ccagcgacgt gtcctacacc
    10441 gaccgcgcga agatgtggca ggaatacctg cggaacatcg ccgtcgaccg tgtcgacacg
    10501 cggcccggcg ccgtcgaatg ggtccaactc cgcgtccgca cgagcccggt gcccaactac
    10561 gacgccgccg gtcacactca cccgctgccg ccctcggcgg tcgacacccg caaactgccc
    10621 tggtggaagg tgaccgccca tgaccactga ccggaacacg acaccccggc ctgccatgag
    10681 caccggcccc ggtctcgtgc gggcagcccg ggccagtctc ggcggcttga tcaccctgct
    10741 caccacccgc catgtctcgc tctacgcggc ggcggtcctg cgcttcggct acggcctgtg
    10801 ctatctcgtg ttcctgctcc gcgaattccc gcaccgagac gagatctggg gtcccgactc
    10861 cccgtggacc ccggcgctcg cgcaccaact cttcgctcaa accggctggt tcagcttcct
    10921 caccctctcc aacagcctga tctacttcga cttctgctac gcggcggcca tcatcgtctg
    10981 cgcgctgttc ctgctgggct ggcggacccg ggccatgtcc gtggctttcg ccctcgtcgt
    11041 ggcctcattc cacgcgcggg ccatcttcat gaccgacgga ggggacaacc tggttctcct
    11101 gatggccttg tacctcaccg cgactgcctg cggccgacgc tggtcgctgg acgcgcggcg
    11161 cgaagaccgt cgggtacgac cccgcggccg ggccccacgg caggccggca acgacgtgtg
    11221 gaccccgctc agcctggccc ggcaaccggt ggtcacagcc ctccacaact gcggcatgtt
    11281 cgtcatctgt gcccaggtgt gtctccttta cggctccgcg ggcctgtaca aggtgcaggg
    11341 cagttcgtgg caatcgggaa ccgccctgca ctacgtcgtg aacctcgacc tcttcaggcc
    11401 ctggcccgcg ctgtccgcgc tcctcgacca ctaccccctc ctcctcgcgg tgctcggcta
    11461 cctcaccgtg ctgatccaag tggccttccc cttcgccctg ttcagccgcc tgaaatacgt
    11521 gctgctcgtc atgctcctgg ccatgcacct cggcatcgcc gtcctcctcg ggctcccgct
    11581 cttctccgcc gccatgatcg tcgccgacgc cgccttcctg cctgaccgct tctaccgcgc
    11641 ggcggcacac accgcccgcc gcgtcctcga ccgtctgcgc acccacgcat ccaccacgcc
    11701 ctccccgcac gtggcgatgg tgccgtcgca gccgggggaa cccggtcttc ccaggtccgg
    11761 agacgacccg gccctccccg ccggcgtccg cgcacgcggt cagaagtaac cggcggggtc
    11821 cagtgacggg catcgccgcc cggcccggtc gctaccgtgc tcgtgccgcg gggaccgtgg
    11881 ccgttctccc cgctgatgac ggcctgacgg gcgcgcttgt tcagcgcgat gacacgcacg
    11941 tgccagtggt gagcggtttc ggcacaagcg atcgcggagt cgagcaggcg cgtggcccgt
    12001 tcggcgtcgg gcgcggtcgg gctcagtgaa ggggtgggat gagggtgcgg acgccgatcg
    12061 tggaggtggc gtgggcggtg ttctgcgggc cgttctccgg cggccagatc ccccggtcgt
    12121 cgtgggactc cttgcggatc tccagccgtg cgtcgaggtc ggaacggcca gatgtgcgtg
    12181 atcctgggga taccgtccag gccgtacatg gccgcggtca gggggtacat ccgggtccgt
    12241 tcgggcaccg ctatccgcca gccgttcatc gtgggggtca ggccgcccag ccgcaggtgg
    12301 taggtgcgga actcgtacac gccgccgtag ccgcccgtgg tgacctccgg gaggaacggg
    12361 aacatgcggt aggtctccac cgtgaagtgg tcgaggtgat cgccgatgcc gaacggatcg
    12421 gtgctggtga gcaggcgctc gcgctcccgc gccagttccg cggcgtcctc gaagccccgc
    12481 agcaccagca ggcggcgccc gaagatctcg ccgcgctcgg tctcccagca gcccagcagc
    12541 acccccggcg caccggccgc gtaggactcc agctgcgcaa ggcgctgtcg atgggtgcgg
    12601 acaggggcgt gcacgtggag gacgacgcgc tgcacggcac cgatgtgatc ggcacgtccc
    12661 tggtgctcgc caaggcggtc gagcacgtgg gcttcgacct ggtcgtgaca cggggcggtc
    12721 cgggtgctgg ccgcggacgc gccggagttc gcggactatc tggtggtgcc gaaggtggac
    12781 gcgttgcagg cggcggtcgc ggccgtcgag ccgctggcgg tgctggtgcc gtcgtcggcg
    12841 gagggcaagg aggtcgccgc gcggctggcg ctgcggatcg gtccgggcat cctcaccgac
    12901 gcggtcgacg tggaggccgg cggggagggg gtggtggcca cgcagtcggt gttcgccgcc
    12961 gccttcacca ccccgagagc gcgcgcggag tcgcgcgctt cggggacgtc ggccagctcc
    13021 ctgtgttcgg tctcgatgtg ctgggcgtcg tccctccggc tcaagtccac gcgcatcagc
    13081 gggaacaggt gcacctggga gcggatcgcc tgccatgccc cctcggggcg gccatggtgc
    13141 gcggcagtgt aggcagcgtc gtggaactcg aagcggtcca ggcggacgtc ctgcacgggc
    13201 tgagcctgga gggtcggtgg tcgaacatcc ggccggaggg gtgcgggtgc tggacacggc
    13261 ctgggggcgt gcgctggggc ggggtgccgc cccagcgccg gcgcgactac tcccgcaggt
    13321 acgtctcgct gaagctggtg ccgctggtgc cgagcgcgct ggtccgggcc tcgtacgcgc
    13381 cgttcgacgg gtcgagcgcg gtcgggccgt aggagccgag ggagctcccg ttgacggtgg
    13441 ccgaggtgaa gttgagggtg ccgaagttcg ggtaggcccc ggtcggcgac tcgatgatga
    13501 cctcggcgct ggcccgttgg gcggagaggg acttgttgat gctgtaggtc cagccacgcg
    13561 tggagtcggt cagcttcagc gcgtacgtgc tgccgctggt gttggtcacc gaggcggtga
    13621 tgtggtcacc ggccgcgacc gggtacgaag tgcggctgag gtagaccgga ctcgccgggt
    13681 acatctcgta ccaggcctgg tgaacggggc tgccgctgga gcagtcggtc gccacgcctg
    13741 tctgctccac ggtggacgag ccgtacccgt cgatgccgac ccagggggcg tagaggtcgt
    13801 tggtggagtt gcaggtcgcg ttcgcttcgg tccaggcggc cgagaccgag gtgaagccgc
    13861 tgcccgtggc ggcgtacccg ccccagttgt agccgttgat gttgtagtgc agggggcgga
    13921 aggacagtcc cggtgcggcc gccgcggtgg ccggaacggc cggagcggca aaggccgccg
    13981 cagccgcgac ggtggcgacg cgtatcagga atctgcgcat gctggctcct tcgtgggggg
    14041 tgcaggatgc tcaaaccgcc ggccttgggg gtgtgcggga cgcggcgcgg caattcagaa
    14101 tcatcgatag tcatggacct gtcaatatgg cctctgtgga cctaccaccc tccccggcag
    14161 gaggccggac gcgcgctcgg cgggtgcggc gagcggcgtt ggcgtacccc ggggacagcg
    14221 tcgaggcgga cgaagtggcc gacgccgtcg ggggcgaggt gccggtagag ggcaaccgcc
    14281 agtgcggcac cgaggaccat ggggagcagc agtccggtga ggcggaccgc ggccacggcg
    14341 ccgcgggcga tgcggccgcc gcccaaggga tcgagttgtc cccgcgcagc ccccgggcga
    14401 tccggctctg ggcgaagggc cgcgcccgtg cactcgcccg gcagggcgac tgcgccggaa
    14461 cggcacgagc gatcggccga gcactcgacc tgacgaccac ggcgtcggca ccgcccgcgg
    14521 cagtgatggc caggttgcga accctcaagg gctgatgacg gctaccagcg cacggggctc
    14581 ccggaggtgt ccaggtgctg ttgcgaacca tccagtgctg atgacgacct gtacgacgtc
    14641 gccgccgtcc tggaggaccc accgcgggac ggcgtgccgg acttcacccc cgtcgagtcc
    14701 cacgccccgg cacatggcgc gtgtttcggc cccggggcga cgtttgtccg ggagtccacc
    14761 agctgtcccg gcaccgcgga ggaggaggcg ccgggccgga cgcgaagcgc ccgagagcgc
    14821 tgctgactac cggtcagcaa actcggcatg aggtcagcat ccgtcctggc acaccctgtc
    14881 acacgcggac gcacaggcga atccgcgacc gcgccgacca cgctttccga gcctcgcgag
    14941 cgcgggtggt ggacggcgtg cggcgccgtc acccgcccgc tcgggcgccc tcggtcaagg
    15001 gcacgggtgg catcggcgtt cttgcaggtc agcgctcgcg gccgcgcggt ttgagggggg
    15061 tgggcgggag ctccggggcc aggaggcggt cgccgtcgta gccgtggacc tcgccgaaac
    15121 ggttcccggt gtgccagtcc tcacgggcct gggcgatgtc ctcgccggtg cgcccgacga
    15181 agttccagaa catgaccagc ttctccgcga agggctcgcc gcccagcagc atgagggagg
    15241 cggagctgtc ggccaggagg gacaggtccc ggcgcccggc gccgaggtag aggagcgacc
    15301 ccggggtgac ggccaccccg tcgacgtcca cccgcccgga catcgccagc gcggcgtact
    15361 cgaagtccgg ctggagcggc agccgcgcgg cggtgccctc ggcgagggtg aggtcggcgc
    15421 cgaccagggg cgtgtggacg gtaccgggcg acaccgcacc gtcgagctcg ccgaggatca
    15481 ccgtggcgtg cagcccgtgc gcagtgacct cgggcagctc cgcgtggtgc tcgaacgcgg
    15541 gctccgtgtt ccggtgcgcg tcgggcagcg ccacccacaa ctgggcgccg tgcaggtagc
    15601 ggccgtggtc gcgcggcgac tcctcggagt gcgagatgcc ccgcccggag gtcatcagcc
    15661 ccaactcccg tggccgtacg gtctgcttgc tgccgaggct gtcgcggtgc agcacctcgc
    15721 cgtcgtgcag ccagctcacg gtctgcaacc ccgtgtgcgg gtgcggcggc acctgcatgc
    15781 ccggttcgcg ggcgatgtcg tcggggccgt agtggtcgac gaagcaccac gcgccgatca
    15841 tccggcggcc gaggttgggg agcagccggc gcacccgcgt gctctcaccg aggggcgtga
    15901 tgcggccggt gagcagttcg cggaccgggg cggcggacac gtcctcgcgg cccccgcaga
    15961 cgctcgcgga cggtttcaca tcgagattgc tcatggtccg atcatgcacc gggttgcggc
    16021 cggggcgccc gaggcggctc caccagccgt tccgggatgt ccgccaaccg gccgcgcagc
    16081 cgctccccga gcgccttcgc ctgggggtcg gcacgggtgg acgccgccac cccgtcgccg
    16141 agcaggtcgt gcacgacgaa gttcaacgcc cgcaggttgg gcagttcgta gcggctgacc
    16201 ggcagccggg ccgcctcggg cagcagcgcg cgcagccggg gcacgtcgag gtacgtacgc
    16261 agccaggcgt aggcgtcgtc gtccgcgacc cacaggccga cgttggcgtc gccgcccttg
    16321 tcccccgacc gcgcgccgac cagcgtgccc agcggcaggc gtacggtcct gccgggctcc
    16381 gcgccggtcc gcccaccgta cggctccgcg cgctcgggcc gcggcgcgcc cgcgaccggg
    16441 ggcggcggcg ggggcacggc gtcgggcctc acccccggcg cgacgcgccc cggcaacagc
    16501 ccgccgcccg gcccgccccc gaccgctacg gcaccgggcg gtacggcacc ggccgctacg
    16561 gcaccgggcg gtacggcacc gggcggtacg gcaccggacg ctgcgccttc ggccccgggc
    16621 ccctccgccc ccgaccgccc cgggccgccg gccctcggca ccgccagccg cgtaccgtcc
    16681 gcgagcaccg cgacctccgc cacctcttcc gccgggacca acgccggcca gtacacgccg
    16741 tactcggtcg ggcgggcggt ggcgtgctcc aggtagaggc cggggtagcc ggccagcgcg
    16801 gtgccggcga cggcggagaa gaagccgcgg ccgaccttgc cggggtcggg gtccttcacc
    16861 gtcagggtga gccggtccac ctcgtggccg tgctcgcgcc gcaggtcgta cccggcgaac
    16921 gcggccgggc ccccggtggc gtcgcgcagc gcggcctcgg cgaagtcggc cttggcgtcg
    16981 aggtcgaggc cggtgagcac gaacaccgcg gagttgcggt ggccgccgac gtggttgacg
    17041 cagaccttga gggtgtcggg cgccggttcg ccggtgaccg ggccgaccgc gacccggtcg
    17101 gtgccctcct gggtgaggcg gacggtgtcg aaccgggcca ccacgtcggc gttgaggtag
    17161 gcgggatggc cggtctcgta gagaagttgg gcggtgacgg tgccgacggt gacggcaccg
    17221 ccggtgccag ggtgcttggt gatgacgctg gagccgtccg ggtggacctc ggcgatgggg
    17281 aagccggggt gcaccgggtc ggggatctcg gtgaagaagg agtagttgcc gccggtggcc
    17341 tgcgtgccgc actcgatgat gtggccggcg gtgaccgcgc cggccagcgc gtcccagtcg
    17401 tcgggcgccc agccgaacgc ccacgcggcg ggcccgacca cgagcgacgc gtcggtgacg
    17461 cgcccgcaga ccaccacgtc ggcgcccgag cgcagcgccc gcgcgatgcc ccagccgccg
    17521 aggtaggcgt tggcggtgac cggctcgacg cccgcggcgg ccagcgggcg gccggtggcg
    17581 aggtgggcga aggcgtggcc ccgggagcgg agttcgggca gccggccgag caggtcgtcg
    17641 ccctcgacgt gggcgacgga gggccgcagc cccgccgccg cggcgagttc gcggagcttc
    17701 gcggcgagcc cggccgggtt gaggccgccg gcgttgacca cgaccttgat gccgcgctcc
    17761 aggcaggtgc cgagcacgtc gtgcatctgg gcgaggaagg acagcgcgta gccgccgtcc
    17821 gggtcgcgcc gccgggcctt ccacagcagc agcatggtga gttcggcgag gtagtcgccg
    17881 gtgaggacgt cgatcgggcc gccctcgacc atctcgcggg cggcggcgag ccggtcgccg
    17941 tagtagcccg agcagttggc gatccgcagc ggtgcggtgc gcccgcggcc gtggaccggc
    18001 tcgccggccg gagcggtcgt gcccaccgga ccgttcgccg cactggtcac cgtactctcc
    18061 cgtcacttcg ccccagggtc accggccccg gcgatcatcg tgccgatgcc cgcgccgcgc
    18121 aagaccccgt gagggcgggg atcggacggc cggtggttga atcgcgggat gaaccaacct
    18181 cccgcgcgcc ccgatccggc cgaacgcccc gatccggccg aacgccccga cgccggcgcg
    18241 cccgacgacg acggcggccc gctgtccgtg cacgaggtca tcgacatcgt ggacgaggac
    18301 gaccacgtcg tcggcacctc gccgcgcggc gaggcgtacg cgcgcgggct gcggcaccgc
    18361 tgcgcgttca tcctggcccg cgacgaccgc gaccggatct tcgtgcaccg ccgcacgtcc
    18421 cgcaagctcg tcttcccgtc cctgtacgac gtcttcgtcg gcggcgtcgt cggggcgggc
    18481 gagtcctacg acgagacggc cctgcgcgag gccgaggagg agctgggcgt gtccggactg
    18541 ccgcagccca cccgcctgtt caagttcctc taccgccagg agaacggccc cggcggctgg
    18601 tggtcgacgg tgtacgaggt acgggtcgac ggtccggtgc ggccgcagcc ggaggaggtc
    18661 gcctggcacg ccttcgtgac cgaggaggag ctcgaaacgc ggttgcgcga gtgggagttc
    18721 gtgccggacg ggctggaggc gtaccgccgg ctggcccgct ggcgggcgga gcgctgaggc
    18781 cgtccggcgg gtcgtgccgg gtcccggggc cggtcccgcc cgcggcttct caggtcaggc
    18841 cgagcgcctg cgcgatcacc ggccacgacg tcttgtactc ctgcttccag tacgtccaac
    18901 tgtgcgtgcc gccggtgtag aagtgggtct ggaccgggag gccgagcagt gccagccgca
    18961 cggcgaacgc ctgcgagccg ggccacagcg tggtctccag cgcttcggcg ctcaactcgc
    19021 cgttcccgcc cacgactccg gtcccggagg agaggaagag cttggtgccc tggaggcccg
    19081 aggcgagcgc gaacgggttc tcggcgttcc acagcgggaa gttgaggacg ggcgagcccc
    19141 acagcgacat cgggtccagt ccctcgcggg cgacgatcgc ctcgaccacg gtcggcatgc
    19201 ccggcatcgt ggtgtcgagc acgccgctgt aggaggccgc ggcggcgaag gtgcccgggt
    19261 gccgcgcggc gaaggccatc gccgcccagc cgccggtgga caccccgccg atcgcccggg
    19321 tggcgccggc gcggtagtcc tgctggagga gctgcatcaa ctcggtgacc tggaaggtct
    19381 cgtagtccgg gtggccgctg ccgtagttcc accaggcgct ggggatgccg gtgggaccgg
    19441 acgacggcat ggcgacgatc acctccttgt cggcggtgaa ctgctcgatg tcggtctcgc
    19501 gcgtccacga ggtgtagtcg tcgtgggcgc cctggagcag gtagagcacc ggccaggtgc
    19561 ggccggcctg ggccgaccag tcggccggca gcagcaggcg ggtggagacg gtgccgccga
    19621 ccgcgggcga ggagatccgc aggtccacgg tgcgcgcgtc gagccaggtc tgggagacga
    19681 cggacgcgcc gtccgcggcg gtgcctgcgg gtacggcggc ggcaccctcg cgcgcggtgg
    19741 cggccggtgc cgggcccgcg gggccgagga ccagcgccgc gctggccgcg agcgtgacgg
    19801 ccagtgccgc ggcggccccc ggaagacggc ggtgcgtgtg catgggacac ctcatgtcgt
    19861 aggcggttcg gggcggaagg ggttcatggc gtggggagtt cgcggcggac ggtccaccgg
    19921 cgcggacacc cgggttcggg gtgccgggga cggatccgcc cggtgcggac gtgccggggg
    19981 cggacccgcc gggtgcgcgt tcaccgttcg cccggctcgg gccgcggggg ctcggtggcg
    20041 ccgccggcca ggtcgcgggc caggagtgcg gcgagttcgt ccaccacggg cgggtcgagc
    20101 agcgccaggt ggtggccggg cagcgggcgg acggtcaggt cccggcagtg ggcgtcccag
    20161 ccgagcgccg ggtcgtcgcg gtcgtagcgg ggatcgcgca ccgtgtgcgg ggccggctcg
    20221 gtggcgcggt agagcagggt ccggccggcg taggggcgcg gggtatgccg ctcggcgctg
    20281 cgcaggtcga ggtacgacgc gcgctggtgc tccagcacgg ccgccggcag atcggccgac
    20341 cgggcgaggg cgccgacgac gagatcgacc tgcccggcgt cgtcgagtgc cgccagccgg
    20401 tcgtagggca ggtcgagccg ggcgccgtag gtctcctcga cgtaccgggc gaagccggag
    20461 aagcgccgca acgcctcgtc gcgcggggtg agtcggggcg cgggcagcgg cagcacgctg
    20521 tccaccagca ccagcgcggc caccgccccg ggcgtcgtac gccgccgcgg gtcgcggtgc
    20581 ggctccgggg ccgtgtcctc gggggcggcg agcagccggg cggtctcctg cgccagcagc
    20641 ccgccgtacg accaaccgcc cagcacccag ggtccgttcg gccggacatc gcggatcgta
    20701 cgggcgtacg cgcgggcgcg gtcgcccacg tcggccaggg cgggcagccg gtccaggccg
    20761 tagcaggggc ggtcggggcc gagccgccgg acgaggccgc cgtagaccgc ggaggagccg
    20821 cccgccgggt ggaagaggaa gagcggcgca ccggtgcccg cggcgctgag ggtgcggacg
    20881 gggccgccgg tcgccgactc cagccgtggg cgcaggagtt cggcgaccgc ggagaccgtc
    20941 ggcggacggg tcagcagctc ccccggcgcc accctgtacc cgctgcgccc ggtcagctcc
    21001 gcggcgaacc gcgccacgtc gtcgaacggc cggccgggca gcccgagatc gtcctcggcg
    21061 ccgggcggcg gaccgcccgc gacggtggcc caggcatggg cgaccagccg ctcggcggcg
    21121 tcgcgcggct ggatacgacg ccggcggccg ttctgccccg accgggcggg ggcggccgcg
    21181 tcctccgacg gccgtgtgga ggcggcgggt tcggtcaccg gcggggtggg cggcacgggc
    21241 acgggcggcg cggtgtccgc caggactccg gtcgcggcgt ccgccggggc tccggtcgcg
    21301 gcgtccgccg gggctccggt cgcggcgtcc gccggggctc cggtcgcggc gtccgccggg
    21361 tcgtcgccgt ggcgcgccag ccaggccgcc agcgcctcca cggtgccgtg ccgcagcagc
    21421 acgcgcggct cgacggcgac gccgaagtca cgccccacgg cggcgaggat gcgggccgcc
    21481 atcagcgagt cgaggccgag gtcggtgagc ggggtgcggg ggtcgatgtc ggtcggggcg
    21541 tagcccatga cctgggcgac gtggccgagc aggcgcccga ggacggtcgg ggcgcccgac
    21601 gccgccaccg cgccgcccgc gccgggggaa ccggcagcgg gctcggaagg gggtccggaa
    21661 gggggtccgg aagggggtcc ggaaaggggc ttggcggcag ccccggcagt gaatccggcg
    21721 gcaggcgcgt ccccgtccgt acctgtggcc gccgcgccga actcgcctgg ggcggcggcc
    21781 ggttcgggcc cgcgccggtg caccgccgtg gccgtctcca cccagtacct gcggtgccgc
    21841 cagccggccg aggggacgtc ggcgggccgg gcccccgggt ggagcaggtc ccgtgcgacc
    21901 gccgtgccgt gcagcaggtg tgccgccagg cccgtgcgga aggtgcgggc gtcgtccgtg
    21961 ttccggcgca gcgtcggcag cagtaccgcg ccctcgatcc cctgggcggc caacgtctcg
    22021 gcgagcgggt gcagttgggt cgggtgggcg gagatctcga cgtaggtccg gtggccgtcc
    22081 tcggccgcgg cggcgaccgc ctgcgcgaag cgcaccggtt ggcgcagccc ggcggcccag
    22141 tagccggcgt cgaaggcggg cacctcgcgc gggtcgtcca ggacggtgcc gtagaacgcg
    22201 cggcccggca cggtgtgcgg cacctcgccg agttggcggg tgagcggcgc cagcagcggg
    22261 tccacctgcg gggagtgccc ggcggcgacc acccgcagcg ggcgggccag cccgccgagc
    22321 cgccgcacca tggcgaccag gttgtcgatg tcggcggccg tcccggtcac gacgctctgc
    22381 gcgggcgagg agtgcaccgc gacccgcacg ctcgggaagg tcgcggcgtg ccggcgcacc
    22441 tcggccgccg acagctccac caccgccatc gcgccaccgg acagcccgtc gagcagccgc
    22501 gcccgggtac cgatgacccg cgcgccgctc tcctcgtcga tcgcgcccgc gacgaccgcg
    22561 gcggccacct cccccatcga gtgcccgatg acggcggccg gttccacgcc gtaccaccgc
    22621 cacaggccgg ccagcgcgac ctggagcccg aagagcaccg gctgcaccac ggagggggtc
    22681 gccaggtcgg cgtccggccg caggtgcgcg cgcagcgaga gtccggcgtg gcgttccagc
    22741 agcggttcca ggcggtccac ggccgcggcg aacgccggct ccgcggccag cagccggcgg
    22801 cccatcccgg gccactgcga gccgtagccg gagaagaccc acaccggccg gggcgcgccg
    22861 ccgttcgacg ggctcggcgg gtaggccggt cgggggccgt cgggtggcgg cggggcgggg
    22921 cgtgccaggg ccgggtgcgg ccggccggtg gccaggcggg ccagcgcggc ggcggcctcg
    22981 tcgtggtccg cggccacggc ggcggcgcgg tgcctgcccc gcccggtacg gccgtgcagg
    23041 gtgcgggcga ggtcgcgcag cggcaccgcg cggccgggcg gggaggccag ccagcgggcg
    23101 agtgcctcgg cggcggcccg cagccgggcg tccgacgggg cgtccagcac caggacggcg
    23161 ggcggcggtt cggcgacgac cacgggcgcc ggccggcgag cggctgcggt cacgggctcc
    23221 ggccagcgag cggcggcggc cgcggtcgcg ggttccggcc cgggaagcgg agcggtcgcg
    23281 gcgtccccgg gggcggccgc ggtcacgggt tccggggtgg gcgcggagga cggcgcggcg
    23341 gcggggccgc tcgcgtgggc cggtcggtgg agggccgccg gggggcaggg cccggtgggc
    23401 cggtactccg ccagcgtgac atgggcgttg gtcccgccga atccgaacgc ggagacaccc
    23461 gcggtcgcgg tgccggagta gcgcggccag ggttccggcg cggtcacgac gcgcagcccg
    23521 agcgcgtcga agtcgatcag cgggttcggc tcggtgaggt ggaggtgggc gggcagcagg
    23581 ccgtggtgca gcgccagcac cgtcttcgcc aggccgacca ttcccgccgc ggcctccagg
    23641 tgcccgaagt tggtcttggc cgagccgatc agcagcggct ggtccgggtc ccggccggtg
    23701 ccgagcacgg cgcccagcgc ctgcgcctcg atcgggtcgc cgagcgcggt gccggtgccg
    23761 tgggcctcca cgtagtcgag cagcgcgccc cgcgggccgt gcgcctggcg cagcagggcg
    23821 cgctgcgccg ccgggttggg ggcgagcagc ccgttggagc ggccgtcgga gttcacggcg
    23881 gtgccgtgga ccaccgccag cacccggtcg ccgtcccgtt cggcgtcggc gaggcgcttg
    23941 agcacggcga cgacgcagcc ctcgccgcgc accatcccgt cggccgacgc gtcgaaggtc
    24001 ttgcagcggc cgtcgggcgc gagcgccccc gcgcgttgga acgcgagggt cagcgcgggg
    24061 gacagcagca ggttgacgcc cgcggcgagc gcggtgtccg tctcgccggt ggcgaggctg
    24121 cgcaccgcgt ggtgcaccgc caccagcgac gacgagcacg cggtgtccac ggccatgctc
    24181 ggcccgcgca ggtcgagcgc gtacgacagc cggttcgcgg cgatgctcag cgccgcgccc
    24241 ggcggggtcc acgcgtcgac cgcgccgagg tcggcggtgg tcagcgacgc gtactcgttg
    24301 ccgctgatgc cgacgaagac gccggtggcg gtgccggcca gttcggtggc ggggatcgcc
    24361 gcgtggtcca ggccctcgcg ggcgacctcc aggagcaggc gctgctgcgg gtccatccgc
    24421 acggcctcgt ggggggagat cccgaagaac tccgcgtcga aggcggcgat gtccggcagg
    24481 aacgcgccgt gccggctgac accctccaac cccggtccgc ccggcccagg ttcgccgggc
    24541 cccgatgcgg actccgcccc gccggtggcg ccttggcccc ccggagccgc acgatccggc
    24601 tgcgccaggt tcacccccgg tccgcccgcc cccgggccgc ccggccccgg ctcgccgggc
    24661 cgtcggccgg cacggctgcc gacggcgggc gggaggaacg gcgcccagcg gtcgtcgggc
    24721 acggtgccca ccgcgtcccg cccctcgcgc agcagctccc acagtgccgc gggcgaggtg
    24781 gcgccgccgg gcaggcggca gccgagcccg acgacggcga ccgggacggc ggccggacct
    24841 cgccccggcc ccggctccgg ggcccgctcc gagccgtgct ccggacctcg gccaggcccc
    24901 ccggccggac cggggacgga cagctccggc cgggggtgtg cggccgcgtc ctgcgcggca
    24961 ccgccttcgg cgagcgcccc gagcagccgg ccgagcgtcg tggcgtccca cagcgcggtc
    25021 ggtgccagcg gcaccccggt cagggcccgc aactcgccgc tgagcgcgac cgcgtcccgc
    25081 gaggtgagcc ccaactcggc gaacgggcgg tcgtcgtcga tgtcggaggg gtcgagcccg
    25141 taccaggccc ccagccgcgc cacgatcgcc tcccgcacct ccgcccccgc ctggcgcccg
    25201 cccccgccgc cgtccccggc gcccggtgcc ggtgcacctg cgacacggcc ttccccgacc
    25261 ggggcgggcg gcgggcccgc ggccgtactg cgtcccgctt cggacgccgc gggcacggcg
    25321 agggacgggg tggacgccgg gaccgggggc tcggccgggc cgggcggcgg agtggggtgg
    25381 tcaggcaccg ggtgcggcct ccttcgcgag ggagccggtc agatagcggt cgcggcaggc
    25441 cgaacgggag accttgccgc tggacgtgcg gggcaccgcg cccgggggca cgagcaccag
    25501 acgggcgagc cgcacaccgt ggcgggcgga cacggcggcc cgcgcggcgc cctcggcggc
    25561 cgtacggtcc tgggcggtgg gcccggcgcc gcgccggtac tcggcgacgg cgacgatgtc
    25621 gggggcggcg tcggcgtccc gggcgccccg cgccggcggc accgcgaaga cggcgaggcg
    25681 gtcccggcgt accacgggga gcgccgcctg gacggtctcc tccaggtcct gcggatagtg
    25741 gttgcggccg tccacgacga gcaggtcctt cagccggccg gtgacgtaca cctgcccgtc
    25801 gtggagcgcg ccgaggtcgc cggtgcgcag ccagtcgccg tactcgccgg tgatgcgggc
    25861 ggcgaaggac tccgcggacc ggtcggcgcg cttccagtag ccgaggccga tgttggggcc
    25921 gcgcagccgg atctcgccga cgtgtccggt gggcagcggg cgcccggtgc gcgggtcggt
    25981 gatcctcagc acctggccga ccgggatgcc gcagccgacc agcgtcacgg gggccgggcg
    26041 gccctccacg gcgccggccg cctcccgctc gctcccccct tccgccgcgc cggccggcgt
    26101 ccgctcgccc gtcgcctccg ccgccccgac gtgctcctcc gcgcccgccg gcacgatccg
    26161 gccctccgcc agcgcgtcgg cgtcgcaggc gagcgtgcgc ggcggggcgg tcggcgggtc
    26221 cgtcgtggcg aagacggtgg cctcggccag gccgtaggag gggcagtgcg cctgcgggcg
    26281 cagcccggcg tccgcgaagg cggcgtggaa gcggccgacg gtgccgggcc ggaccggctc
    26341 gctgccgttg atcagcgcgc ggaccccgtc cagccgcagc cccgcggcct gctccgcggt
    26401 gatccgggcg gcacagtagt cgtacgcgaa gttgggcgcc gcgctgatgg cgccccggta
    26461 ggtggagagc aaccgcagcc agcgcacggg ctgttcgagg aaggcgaccg ggtcggtgag
    26521 gaccgagggg aagccgccga cgaccggcgc ggcgacgctg agcaccaggc ccatgtcgtg
    26581 gaagagcggc agccatccga cggtggtcgt gtcctcgggc gtggcggcga acgcgtcgat
    26641 cgcctgctgg gcgttggcga cgacgttccc gtggctgatc atcacaccgg cggggacgcg
    26701 ggtggagccc gaggtgtact ggaggtaggc gatgtcctcg gggtcggcgg tcggccacgg
    26761 gatccggggc ggcggctcgg ccccgggcgt ccgctcgacg tggagcacgg gtaccggcgg
    26821 gatgccgtgc tcggcgagga acgcgtccac cgcgggcgcg gtcgcggcgt cggtgagcac
    26881 gcagcggggc tcgcagtcgc cgagcaccgc cgcgagccgg tccgcgtgcc cgggcaggtc
    26941 ggggccgaac agcggcaccg cgatcacccc ggcgtacagg cagccgagga acgccgccac
    27001 gtagccgagc ccctggggca gcatcagcgc ggcgcgctcg ccgggtccga cccggccgcg
    27061 cagccgcagc gcgatgtcgc gggcgtgctc gtccagccgc cgccaggtga gcgtccgcgc
    27121 ccgcccgggc gagtcggggt ccgggtagtc gacgaaggtg aacgcccgct gcccgccgcg
    27181 ctccgccgac cagcggcgca gcgactcggt cagcgggacg ggacgcgcgg ggggaggtgt
    27241 cggcacgggc actcctggag aggggtagcg gcacgggcgc acggggccgg ccgggtgtgc
    27301 gggagatcgg ggcgcggggc ggagcggagc ggacggcggg ggcggatcag ggggcgcggg
    27361 gagggggcgc ggggaggggc aggagacggg gcagggggca ggagggggcg ggtcaggtca
    27421 ggtcaggtca ggggatcaga gcgggatgtt gccgtgccgg cgctgcggca gggccagttc
    27481 cttcgtccgc agcgcgcgca gcccccggac gatccggccg cgggtctcgt gcggcatgat
    27541 cacggcgtcg aggtagccgc gctgcgcggc ctggaacggc gtggcgaagt cgttctcgta
    27601 ctcctcgacg agttgcttgc gcagcagttc ggggtcctcg gcctcgctca gcgcgcggcg
    27661 gtgcaggatc gcgacggcgc cctgcgcgcc catgacggcg atgcgggcgg tgggccaggc
    27721 gaggttgagg tcggcgccca ggtgcttgga gcccatgacc gcgtagccgc cgccgtacgc
    27781 cttgcggacc acgacggtga cggtgggcac gctcgcctcc gcgtacgcgt agaggagttt
    27841 ggcgccgcgc cggacgatgc cctcgtgttc gagccggacc ccggacaggt agccggggac
    27901 gtccacgaag gacagcaggg ggatgccgaa cgcgtcgcag aaccgtacga acctggcggc
    27961 cttctccgac gcgtcgatgt cgagcgcacc ggccgagtgc agcggctggt tggcgacgac
    28021 gccgaccgag gagccctcga cgcgggcgaa ggcgcagatg atgttgggtg cgaacagctc
    28081 ctgtacctcc aggagttcgg cgtcgtccac gacgcggcgc aggacgtccc gcatgtcgta
    28141 ggcgcggccg gggtcctcgg gcacgatggc gtcgagttgc aggtcccgcg cggtgaccga
    28201 ggggtcggcg cgcaggccgt agtccggggg cgcgtcgcgg ttgttggcgg gcaggtagga
    28261 cagcagcacg cggacgaagt cgaaggcgtc cgcctcgtcg tcggcgacgt agtgggcggt
    28321 gccgctgacc gtgccgctgg tgtgggcgcc gcccaactcc tcggcggtgg tgacctcccc
    28381 ggtcaccgag cggatgacgt cggggccggt gacgaacatg tgcgaggtgt cgcggaccat
    28441 cacggtgaag tcggtgagcg ccggcgagta ggcggcgccg cccgcgcacg ggccgaggac
    28501 gagggagagc tgggggacga cgccggaggc cctgacgttg cggtgcacga gttcggcgta
    28561 gtgggcgagg gcgacgacac cctcctggat gcgggcgccg ccgccgtcgt tgaggccgat
    28621 gacgggacag ccgaccttga ccgcgtggtc catcaccttg gcgaccttct gcccgaacgc
    28681 ctcgcccatg ctgccgccga agacggtggc gtcctgcgcg aacaccgcga cctgccggcc
    28741 gtccacggtg ccgtggccgg tgacgacccc gtcgccgtcg ggccgccggg agtccatgcc
    28801 gaacgcggtc gcgcggtgct ggacgaaggc gtcgaactcg gtgaacgacc cctcgtccag
    28861 gagcgcgtcg aggcgctccc gggcggtcag ccggccgcgg gcgtgcaggc gggccacggc
    28921 ctcgggcgga ccgccgcgca gcaggcgggc gcggcgggac tcgaactcgg cggtgcgcgt
    28981 catgcgcggt cctcctccgg ccagggatgt cgtggacacc acaggctccg ctcggccggg
    29041 tgggcggggg tagtgcgggg cctgacagcg ggcggcacgg gcgctgtcac ttcggtgaca
    29101 aggcggtcgg agcgccgggc ggggtgtgcg ggggccgcgg cgggagcgct gaggtcggtg
    29161 agcgcccggg ccgggcccgc tgtcatccgg atgacaacgc agcggccgcc gcccgcactg
    29221 tccggttcac cactggtgca ggtgttgcta ccggagagta aggtcacggc actccacccg
    29281 atcgagcgga aggggccgtt ccgtggtgag acatggggcc gtactggcgg aggagccgtt
    29341 ccaccggttc tccgccgacc tcgccgagca cctgcgcccg ctgaccgagg acatccggcg
    29401 cgaggtggtg aacgccatcc tcgccggcat ccccgagtac gcccgtccga ccaacgccgc
    29461 ctacaccacc accatcacca ccggcgtcga actcggcctg aacctcctgc tcgaccggct
    29521 caccgcgccc ggcatcggcg cccgggaggt cttcgacatc taccacgcca tcggccgcgg
    29581 cgaggcacgc gaggggcgca ccctcgactc cttccagggg gcgctgcgca tcgccgcccg
    29641 catcacctgg cgcaccatca gcaccctcgc cgactccgac acgctgcccc gccaggagct
    29701 cgcgctgctc ggcgaggccg cgctggtgca cctggacgag atcgccgccg ccacctcggc
    29761 cggcttcgcc gaggcccagg cccacctcgc ggacgagccg cgccgccgcc ggctgcggct
    29821 gctcgacatg ctcaccgacg agcagccgcc gaccgctcag gccatcgcca cgctcgcccc
    29881 cgccgcccgc tggccggtgc cctcgcggat cgcggtcgcg gtgctcgacg gccactggga
    29941 acgggaggag tcgcggccga tcctgccgcc cgacctgctc gcggacttcg accgcaagcc
    30001 ggtccgcgtg gtggtgcccg accccgaggg ccccggccgg gcgcgcgcga tcgaggcggc
    30061 gctgcgcggc caccgcgccg cgctgggacc gacggtgccg ctcaccgagg gcgccaggtc
    30121 gctgcggtgg gcgctggacg cactgggtct ggcgcgccgc tccgtgctgc cctcgcgcgg
    30181 gctggtgcgc tgctccgacc acctcaccac gctcctgctc ttccaggacg aggacctggt
    30241 ggacgcgctc ggcacccgcc acctggaccc gctggagcgc atgccccgcc cgtaccgcga
    30301 ccggctcgcg gagacgctgc tgtcctggct gcggtgcagc cgcaacgcca gcgaggtcgc
    30361 ggtcaggctg ggcatccacc cgcagaccgt ccgctaccgc ttacgccgcc tcgacgacct
    30421 gttcggcgac cggttgcagg acccggacgt gtgcttcgag atggaactcg cgctgcgact
    30481 gcggcagatg cggccgcggc aggccggttg agccggagcg cgccgcgccg cccgctccgg
    30541 ccctcgcccg tcggaacgga ccgtgggaac cgcccgtcgg aacggaccgt gggaaccgac
    30601 cgtgggccgt gggctgcacc cgcgggaggc gcccgcggaa tgcgcccgcg gaccgtcgac
    30661 gcggcgccgt cccgggcgcg ttgtcagccg ggtgatgacc gaaggccgca cggtgcgcac
    30721 acggtgcgta gccgaggtga cggaccgtca gtaggctgcg agccgtccga gcgcaggccc
    30781 gagcgtgccc aggaggcttt tgatggcagc gagttcggcg gaggcggcgc cctggggtga
    30841 gccgatgcgc acctccgacc gggtggtggt cggcctgttc gtcggcgtgc ccttcgccgc
    30901 ggtgatcgca tccgtggcgg tgctgtgggg ctggggcatc ggctggcacg acgtggtgat
    30961 cggcgcggtg gcgtacgcgg tggccgtgca cggcgtgacg atcgggtacc accggctctt
    31021 cacccaccgg gccttccgcg cggcccgccc gctgaagatc ctgctcgcgg tggccggcac
    31081 gctcgcggtg gagggcgacg tgatcacctg gtgcgcggac caccgccgcc accaccagtt
    31141 cgcggaccgg ccgggcgacc cgcactcacc gtggcgcttc ggcacgtcgg cggccgcggt
    31201 ggccaagggc atggtgtggg cgcatatcgg ctggaccttc accaacgaga agaccaacca
    31261 ggcccgttac gtgcccgacc tgctcgccga ccgcgacctc gtccgggtgg cgaggtggca
    31321 acccctggtc gtggcggcct cgttcgggct gcccgcggtg gccggcgggc tgtgggggcc
    31381 gggcggctgg gacggccggg ccgcgctgtc ggcgttcttc tgggccggcc tggtgcggat
    31441 cggcctgctg caccacgtca cctggtcgat caactcgatc tgccacgtgg ccggtgcgcg
    31501 ccccttccgc tcccgcgacc gctccgggaa cgtctggtgg ctggcgccgc tgtccggcgg
    31561 cgagtcctgg cacaacctcc accacgccga ccccacgtcg gcccggcacg gggtgctgcc
    31621 cgggcagatc gactccagcg cccggctgat ccggatcttc gaactgctcg gctgggcccg
    31681 cgcggtgcgc tggcccgacc gccgacggct ggcggccagg gcggtccggg acggcgccga
    31741 ggggtgaaca ccgggaccac ggcgaccggc gaacggtgac cggcgaccgg tgcccgcggg
    31801 gtccacgggg gccggcggcc gcggggtcca cggcggccgg cggccagcgg ccgcgcggat
    31861 cacggacgca cccggaacgc cggtgcggcc tgagggccta cccggcagat cgtggcgagc
    31921 ctgcgacgcc cggcacgatc cgccggacag gccccacccg gcagaacacc ccggtatggc
    31981 ggcaatgtcc cccgccgcgc cgccccggac ttgaaccggg cccgcgccgg cgtgttcagt
    32041 gggcgccatg acagcccgac ccgccgctcc gctccccctc gtcgtgatca tgggggtgtc
    32101 cgggtcgggg aagacgacga tcggcggcct gctggccgcg cggctgggcg tgccctacgc
    32161 cgaggccgac gacttccacc cggcggccaa cctcgccaag atggcgtccg gccggccgct
    32221 ggacgacgcc gaccgcgcgc cctggctcga cacgatcgcg gagtggctcg ccgggcgcgg
    32281 tctgcgcggc ggcgtggtga gctgctccgc gctgcgccgc cgctaccggg accggctgcg
    32341 cgaggcggca cccgggctgt tcttcgcgca cctggacggc acgccggagc tgatcgcggc
    32401 gcggctggcc ggccgcacgc accacttcat gccgccggcg ctgctggcct cgcagttcga
    32461 ggcgctggag ccgctggagc cggacgagtc gggcaccgcc gtgccgatcg acggcgacgc
    32521 ggagccgacg gtggagcgca tcctggcggc gctgccggcc tgatcccggg ctaccagcgg
    32581 ggcaccgacg gcatgcgcca ctccggatcg gccttgcgca tcgcggcggc gtcgtcccgg
    32641 tcgcgcatcg tgccgtcgtc gtcctgccag cggcggtgca gccgggcgag ggcgtcgcgg
    32701 tcgagttcga cgcccagccc gggggtgtcg gagacggcga gccgcccgcc ggtgaagacg
    32761 tgccgctcgg tgatgacgtc ctcgctctgc cacgggtagt gcgagtcgca ggcgtagtcg
    32821 aggttgggca cggtcgcggc gacgtgggtc atcgcggcga ggctgatgcc caggtgggtg
    32881 ttggagtgca tggacaggcc caccccgaag gtgcggcaga tcgccgcgag gtgctgggtg
    32941 ttgcgcagcc cgccccagta gtggtggtcg gagagcacca cctgcacggc cccccgggcg
    33001 aacgcctccg ggatctccgg gaacgtcgtc acgcacatgt tcgtcgccag cggcacggac
    33061 gtctgcgcgg cgacccgtgc catccggtcg gtgctgctgg cggggtcctc caggtactcc
    33121 agcacgtcgc cgagttcgcg ggcgacctcc agcgaggtct ccaccgacca ggcgccgttg
    33181 gggtcgagcc gcagcggctt gccggggaac gcctgcgcga gcgcccgtac ggcggcgatc
    33241 tcctggtcgg gcgggaagac gccgcccttg agcttgaagg agccgaagcc gtacgcgtcg
    33301 gcgaagcggc gggcctgggc gacgacgccg gccgggtcga gggcggcgcc ccagtcgtcc
    33361 gcctcgccgg cgccctgcgg gtgctcggcg aggcggtaga agaggtaggc gctgtagtcc
    33421 acggcgtcgc ggaccttgcc gccgagcagc gcgtggaccg gcaggcccac gaccttgccg
    33481 agcgcgtcga ggcaggccac ctcgaagccg gagatcaccg acagccggag cttgtccgcg
    33541 gtctgcacgc cgcgcaggcc gctgctggtg acggagtcgg agacctcccc ggggtcgccg
    33601 cacacccgct cggcgagggt gaacagcccg ttcaggtcgt cgagccggtg gccgggcagc
    33661 gcctgggcca gcggcgcggc cagccgcagg tagccggagt cgccgtacgt ctcgccgacg
    33721 ccggtggtgc cgtcggaggt gaccacctcg acgatcagac gcggggtgta gggctggtga
    33781 acgccctggg tgttgagcag cggcggatcg gcgatcagga tgggagtcag ccgcacctcg
    33841 gcgatggtcg ccgaggcggc gccgctcgga gcacccgccg tctgtatata tgaatcgcgt
    33901 tcacccatgg aatcgagcgt aggcgggcgg accggcgacc gtcaatgcgg cccgcggcgc
    33961 ggcgagcccc cgtggccacc cgcgcgcggt ggcgtccgga agggcgccgg agcactggac
    34021 tgcataccga ccagtcggta cgatcccggc atgaccgcat ccgccaaccc gccgggcctg
    34081 gatctcgacc gcctccgccg ccacctggac cgggagctcc ccggcctggt ccgcggcggg
    34141 ctgcgggccg atctgctgga gggcggccgc tccaacctca cctaccgcgt caccgacggc
    34201 gccggcacct gggtggtgcg caggccgccg ctgggccatg tgctggccac cgcgcacgac
    34261 atgggccgcg agcaccgcgt gatcagcgcg ctcgccgaca cccccgtccc ggtgccgcgc
    34321 accctgctgc ggtgcgacga cccggaggtc gtcggcgcgc ccttctacgt gatggagttc
    34381 gtccccggca cgccctaccg cagcgaggac cagctccggg agatcggccc cgagcgcacc
    34441 cgggcggccg tgcacaccct ggtcgacacg ctggtggacc tgcacgcggt ggaccccgcg
    34501 gcggtgggcc tggccgactt cggccgcccg gagggcttcc tcgaccggca actgcgccgc
    34561 tggggcaagc agctcgacgc ctcccgcagc cgcgaactgc cgggcgtgga cgagctgcac
    34621 gccgccctcg gccgctcgct gcccgactcc cccgcgcccg cgatcgtgca cggcgactac
    34681 cgcctggaca acgtgctgat cgacgccggc ggccgactca ccgccgtgct ggactgggag
    34741 atgtccaccc tcggcgaccc gctcaccgac ctcgggctgc tggtgatgta caccgagcag
    34801 cgcagcagcg acctgctctc cgcgcccgcc accggcggcg ccccgggcca ccccggcgcc
    34861 cgcgagatcg tcgcgcgcta cgccgagcgg tccggccgcg acgtcaccgc ggtcgactgg
    34921 tacaccgcgt tcgcctactt caagctcgcc gtgatcctgg agggcatcca ctaccggtgg
    34981 accctcggcc agaccgtcgg cgccgggttc gaccggatcg gcgacgtcgt gccggtcttc
    35041 atcgaccgcg ggctgaacac cttgcggcgg tccggcgccg gtcacctccc caccacccga
    35101 gacgaggact gagcgcccat ggacttcggc tacgacacca ggaccgagga actgcgcgcc
    35161 aggctctcgg cgttcctcga cgagcacgtc ctcccggccg agccggtgtt cgcgcagcag
    35221 cgcgagcagg cggtcggcga cgaccgctgg acggctcctc cgatcgtcga actgctcaag
    35281 gcggaggcgc gctcgcaggg cctgtggaac ctcttcctgc ccggtgaaca cggcgcgggg
    35341 ctgaccaacc tccagtacgc gccgctcgcc gaactcaccg gccgcagccc gcacctggcc
    35401 ccgccggccc tcaactgcgc ggcgccggac accggcaaca tggaggtgct cgccgagttc
    35461 ggcacccccg cgcagcgcaa ggagtggctg gacccgctgc tggccggcga gatccgctcg
    35521 gcgttcgcga tgaccgagcc cgaggtcgcg tcgtcggacg ccaccaacat cgagacgcgt
    35581 atcgagcgcg acggggactc gtacgtcatc aacggccgca agtggtacat ctccggggcg
    35641 atgaacccga agtgcgccgt gctcatcgtg atgggcaaga ccgatccgac ggccgagcgg
    35701 caccgccagc agagccaggt gctggtcccc cgcgacaccc cgggcgtcga cgtccgccgc
    35761 ggcatgcgcg tgttcgggta cgacgacggc gaccacggcg gccacgccga gatcgtcttc
    35821 cgcgacgtgc gggtgccggt cgccaacctc gtcggcgagg agggcggcgg gttcgccatc
    35881 gcgcaggcgc ggttgggccc gggccgcatc caccactgca tgcggctcat cggcatggcc
    35941 gagcgggcgc tggagttgat gtgccggcgc gcgaacgccc gtaccgcctt cgggaagccg
    36001 ctcgccgcgc agggcgtggt gcaggagtgg atcgccgaag cacgcgtgga gatcgagcag
    36061 ttgaggctgc tggtgctgaa gacggcgtgg ctgatggaca ccgtcggcaa ccagggcgcc
    36121 cacaccgaga tccaggcgat caagatcgcc acgccggccg cggtgcagag gatcgtggac
    36181 cgcgcgatcc agttgcacgg cgccggcggg gtgtcccagg acttcccgct ggcggagctg
    36241 tgggcggcgg tccggaccct gcggctggcc gacggcccgg acgaggtcca caagcggtcg
    36301 ctcgcccgcc gcgagctgcg ccgctacgcc tgaccccggg gcggcgcgtc acaccggtcc
    36361 ggggacgtcc ccccggcggt gggccggccg cgcgggttcc cccgcgcccc tgggttcgga
    36421 cggcttcctc cgtgcgaggg gcggcacccg cccaggggcg cgggggaacc tcacggaagg
    36481 acgacgagcc gtcccaccgt cgtgccgtcg ctgaccctct ggacggcgtc ggcggccgct
    36541 gtgaggggaa ggcgttcgct gacgagcggc ttgaccgcgc ccttggcggc caggtcggtg
    36601 agttcgtcgt gggcccgccg gacggccgcc gggtcctgcg tgttgtacag cccccagtgc
    36661 agcccgagga tcgtgtagtt cttcacgagc gcgtggttga gccccggcgc ggggatcgtc
    36721 ccgctggtga agccgaccac cacgatgcgc ccttcgaagg cgatgcactt cgtggaccgg
    36781 gtgtaggcgt cgccgccgac cgggtcgtag acgacgtcgg cgccgcgccc gccggtggcc
    36841 tccttgacca cggccacgaa gtcctcgcgg tgccggtcca cgaccacgtc ggcgcccgcc
    36901 tcgcgtgcgg cgccggcctt ctccggcccg ccgaccacgc cgatgacggt ggcgccggcc
    36961 gccttgccga gctggacggc cgcgctgccg acgccgccgg ccgcagcgtg caccagcagc
    37021 gtctcgccgg ggcgcagcgc ggcgcggcgg tgcaggccga accagccggt ctggtagccg
    37081 atgtgcaggg cggcggcctc ggcgtcgtcg agcgcctcgg gcgcgggcag cacgccggcc
    37141 gcgggcacca ccgcgtactc ggcgtacgcc cccgcgggca gggcgaccgg gctgatgacg
    37201 cggtcgccgg gggtgagccc ggccacgccc tcgccggcgc ggacgacctc accgcacagc
    37261 tcgacgccgg gggtgaaggg cagcggcggc cggacctggt actggccgcg gcacagcagc
    37321 gcgtcgggga agttgacgca ggcggcgcgc acccgcagca gcacctcgcc ggggccgggc
    37381 gccggggtgg gtatctcgtc gaggcgcatc gcctcgcgcg gttcgccgtt gtggtggacg
    37441 cgccatgcct tcacgtggga tctcccgggg tcgcgggcgg ccgcaacgag tgcagcagca
    37501 ggtcggagaa ctcggcggcg acctgctcgg cggtgagcgg gccgtccgcg tggtaccagg
    37561 tgccgaggtg gtgcaccgag ccgaagaagt agtccaccac caggtcgggg cggggttcgg
    37621 gccgcaggag gccgtcgcgc tgcccctcct cgatgagcgc gcggaacgtc tcgtggtagc
    37681 ggcggcgctc ggcgcgcacc gccttctgct tctccggacc gagctggtgg atcgagcgga
    37741 agaagatctt cgtgtcgtcg aggttctgga tgctggtgac gacgacgtcg gcggcggcct
    37801 cggcgatccg ctcggtgacg gggaccgggc gggccgcgat cgcgtcgagc cgttcggtct
    37861 gcagccgcag cacccgcccg tagatctcgt gcagcaggtc gtccttggag ccgaagtagt
    37921 ggtagagggc gcccttggtg acgccggcgg cctccacgat ctcctgcacc gaggtgcggt
    37981 cgtagccgcg ctcggcgaac agccgggtgg cctcggcgag cagccgttcg ggcacggccg
    38041 cggtcgcgcc cggtgcggtg gtgcccggtg cggtggcgcc cgctcgcgcg gtgcccggtc
    38101 ccgtaccgcc gccaccgctg ctgccgctcg tcgccttgcg tgccatggct gccctctcct
    38161 cgtgccgtcc ggtcggccgg cggcgttccg gccggtacgg accctatccg gccgccgccc
    38221 tcagttcgcg gcgcaggatc tttccggtcg tggtcttggg cagctcgacg cgcacctcga
    38281 cctgccgcgg gtacttgaag gccgccagcc gctcccggca gtacgcgacc agttcctccg
    38341 gctcgacggc ggcgcccggc tggagactga cgtacgcctt cacgctctcg ccgcggtagg
    38401 cgtcgggcac ccccacgacg gcggcctcgc ggacggccgg atgggtgtag aggacgtcct
    38461 cgacctcgcg cggccagacc ttgaagccgg aggcgttgat catgtccttc ttgcggtcga
    38521 cgacgtacag ccagccgtcc tcgtccatga agccgacgtc gccggtgcgc agttcgccgc
    38581 cgggcaggcc cgccgcggtc tcctccggct tgttccagta gccgggcacc accatcggac
    38641 cgctgaccgc gatctcgccc tgctgcccga acggcacctc ggcgcccgtg tcgtcgagga
    38701 tgcggaccat ggtgccgggg ccgggcacgc cgaccgcgag ggtgcccgac tccgggtcga
    38761 ccggcgcctc caggcccggc ggcacgctcg cgcacggcgc ggtgcactcc gtcaggccgt
    38821 agccgttggc gaggtagcgg ccgccggagc gggtccggaa ggactcgacc acggcgggcg
    38881 gcagcggagc gccgcccgag gcgatatgcc ggaaggaggc gaagtcgccg ggcgcggcgt
    38941 cgggccgggc gagcagcgcc atgaacgcgg tcgaggggcc gacggtgaag gccgggcggt
    39001 gctcgcggaa cgcgtcgagc accacgccgg gctcgaagcg gtaggcgagc gccacgctgt
    39061 ggccgccggc cagggccgcg gcgagctggc agaccatgcc ggtgatgtgg aagagcggtg
    39121 ccagcacgaa caccaccgcg tcgtccggga gttgctggag gcggacctgg cggtgggcgt
    39181 tgaaggagat gttgccgtgg gtgttgaggg cgcccttggg gtggccgctg gtgccggagg
    39241 tgtagctgac cagcgcggtg tcgtccgcgg cgggcaggtc cgcggcggag cgtaccgggc
    39301 tgggcccggc gtgggcgcgg gcgacggcga ggacgtccgg cggcacgccg gggccgtcgg
    39361 aggcggttcc cgccggggtg gagccctcgg gggcgggacc gtcggaggcc gggagctctg
    39421 acgtcccggg ccgggggcgc tgcccgagca cccgggcgtc gtcgcgggtc tgcaggtcgt
    39481 gctcgtcggc ggtcagcgcg atccggaccg gcgagtcggc cacggtgtcg cggacgtacg
    39541 cctcccaggc ggtgcgcgag cacaggatcg cggcggcccc cgcgtcgtgc aggatgtggg
    39601 ccaactcccc gctcttgtac atcgggttga ccgggatcac gacgccgccc gccttccacg
    39661 cggcgagcag gccgatcacg aactgcggca cgttctggag catgaccgcg aggcggtcgc
    39721 cgggggcgaa gccgcgctcg gcgaggtggc gggcgaggcc gtcggagagg gcgtccaact
    39781 cgccgtacgc cagggtgccg tcgaagtagc gcagcgcggg gcgctcgggg gtgcgcccgg
    39841 cgacggcgag gaaggtgtgc agcacggacg gcgggtgctc gctcgcggcg cgctgctcct
    39901 gcgtgaagtg cttcagccag ggctggtccg cggaggtcgt catgcccgtc cgcccctctc
    39961 cgccccggcg gcgtccgccg gtcgctcctc cgcggcggcg agttgctgct cgtactggcg
    40021 ctggagcttg ttcatgccgc cgagccagcg ctcgggttcc gcggcgcggg cggcgtagta
    40081 gccggccacc tcggggtgcg gcaggatcag gaaccgctcg gccgcgatgc cctcgatcac
    40141 cgcgtcggcc acgtcctcgg gctcgatggc ggtcggcgcg agcaccaggt cgccggcggg
    40201 accggtggtg gagagcatcg cggtgcgcac cccctgcggg cagaccgcgt gcgcgcggac
    40261 gccgcggtgc cggtaggtga gcgacagcca ctcggcgaag gcgagcgcgc cgtgcttggt
    40321 cacggagtac ggtgccgcgc cgatcatcgt cagcaggccg gcggcggaga cggtggacac
    40381 gaagcggccg gagccgcgct ccagccactc cggcagcagg tcgcgggcgg cgcggacgtg
    40441 gctcatcacg ttgacgtccc aggccagttc ccaggcgtcc tcgtccgcct cgggaccccc
    40501 gccggtgccg acgcccgcgt tggcgcagaa cacgtcgatg gtgccgccga gcgcggtccg
    40561 cgcggccggc accacgccgg aggcgtcgcc gggcaccacc gccgcgtcga tctcggcggc
    40621 ggtcgcgcgg gcggcgtcgg cgtcgaggtc gttgaccgcc acccgggcgc cctcggccgc
    40681 gaaccgccgg gcgagtgcgg ccccgatccc gcccccggcc cccgtgacga ccacccgggc
    40741 gccgctcagc gcttccacga ccacgacgtg tctccttcga ctcgacggtg cgaccttctg
    40801 catactaagc ggtcggtcac cgctgcggaa gggcggacgc ggcagggccg ggccccgtcc
    40861 gggacccggc cccacgccgt acggtcggcg ccgccgagcg gcgcctcacg tgtccggcgc
    40921 gtccggcgcg ttcaggcgcg ctgagcacgt ccggcgcgtt caggacatcc aacgcgatca
    40981 acgtgctcgg cgtgctcagc gtgctcagcg tgctcagcgt gctcagcgtg ctcagcggtg
    41041 cgaggggaac tccaccacct gctggtaggt ggggcggttc tgccagctga tccggtcgtc
    41101 ggtgatgccg ccgagcggcc gctgcacgat cgagtcggcg caccactggt cgccggccgc
    41161 gcagccgccg tcgtcgcccg ggtagacggt ggtcgccggg gtggcggccg cctgcttcaa
    41221 cgtggacagc aggatgttcc ggcaggccga gagctgcccg ccgccgcagt aggtgtgcgc
    41281 caacggcccc tgcacgctct gcccgagcac cttgcgcagg tccttgtcga cgtacgacca
    41341 ccagccgtac tggaaggaac tgcccgcgtg cgagccggtc ggcccgtgcc cggccgacgg
    41401 cgactcgtcg atggtcaggt ccgccgccag cgcgttgtac aggtcggtgc cgagccccgt
    41461 ctggaactcg ccctgcacca gcagcggcca ccacgcgtcc atggtccgca ccgcgtccgc
    41521 gtcggcgtac gtgtgcgaac cggccgaggt ctcggtgcgc ttggtgccgt ccgccagcca
    41581 cgtggtcaac tgctggacgg cggcggcctc ctggctgtcg gtcaccggcg cgctcttgat
    41641 cacctggagc agttcgggca gaacgtcctc accgcgcagg tcggtcagcg acgcgctcga
    41701 catcgccttg accagcgacg cccgggtcac cccgccggcc tggaccagcg ccttgacccg
    41761 gtcctccagc aggtcggccc ggtgcaccga gccgttgccg aagcccgccg aggtgtagcc
    41821 gggggcctgc ttgttgttcc aactgatgta gtagtcctgg tcgacggact gcgggtgctg
    41881 cgaaggcggc gtgtaggtcg ccgtgttgtg ggtcgggtcc cagccctgcc agtcgtaggc
    41941 gccggtcccc cacaccggga aggacgcgtc caccccggcc gcccgcaccg ggttggtgcc
    42001 gctgttgtag tacgcggtct gccgggagtc ggcgtagaac cagttgaagg tgtagttgat
    42061 gtcctgcgcc gccttctgga acgacgccgc gtcgtgcacg aaccccgggt cgttcagctc
    42121 ctggaagccg atgatcgagt ccgcctcgtg catgtacgaa ctgcgcaact gcgtgtaggc
    42181 gaccggtttt ccgccgaccg tggcccggta gatcaccggc ccgtacgccg tccgccacac
    42241 ctgcatccgg tacgacccgg cgggggtgga gtccgcgagc gtcggcgtcc aggagttggt
    42301 gcgctccagc ttctccatcg gcacgcagct accgtgcagg atgtagtgcg tgtcgtcctg
    42361 gcagagctgg accgcgtagg tgtcggtcac gtcctgcgag gcggaggtgg cgctccacgc
    42421 gtagtcctgg ccgcggccga gttcgacgta catgcccagc cccgcgaacg acgcgccgcg
    42481 tgcgctgata cccgggccct ggagctcctg gagcatcagc aactgcggtg cgaagtagcc
    42541 ggtctgcggg ccgaacacgg cgaccgggtg gccgctggcg gtgtgcgcgc cgctcaccac
    42601 cagcgcgttg gacatgccct tgcgggggtc ggagaacatg ttcgagggca gcacccccgg
    42661 gctcttggtg gtcgactggg tcgccccgcc ggtcgcgtcg tagaccagcg gctccggcac
    42721 caccgagccg gggtcgggca gcgcctcgcc ctgcgcgctg gccggcttgc ccgcgtacgg
    42781 gaacgaactg ccgtcgtgca cggtcgaggt ggcctccggg tcgtcccgct cccggaacga
    42841 ctcccacacg ttcgtgccgt cctgcacgcc gtacttctgc tgggcggcca gcagcgacag
    42901 cgccgactgc acctctcccc cgccgccggt gccgaagagc gcgccgatca ccgaggcgag
    42961 cgcgatcagg tcggtgagct ggaacggctc gatgtccccg gcgttggtga tggcgttcac
    43021 gtgcccggtc aggtcgtact cgccggggaa gtaccggccg ctcttcgccg cggtgatgta
    43081 ggcgttgatg ccgtcgatgt agtcctgcgc gtccgcgagc gcctgcctgc cgcggtcacc
    43141 gctgttgttg ctgagccagt cgacctgggc ctggaggtcg gcctcggtgt agggcgcctg
    43201 ctgccagaac tcctgctcca ggccgcggtt ggccgccgcg ccgccggcga acgacgacaa
    43261 ctccccccgg ccgacgtgcc ggaagaggtc catcagccac aaccggtcct gcgcggcggc
    43321 gtatcccgcc ccgaactcgg tgccgtcccg cgtggtgccc ttgatgtgcg gcaccccggt
    43381 ggccttgtcg cgggtgatcg tgacgtcgga gcgcgggctg accaccgagg cgacctggtt
    43441 cgagggcacc ccgaacgagg acgagttgaa gaagttgctc agcgtcgcgt ccgtcaggtt
    43501 ctggtacccg gtcgcgagcg aggagtacgg cccgagctgg tcggtcgtgt gggccgggcg
    43561 cgtaccgaac gccttgttgg cgaggatgtc ggcgagggtg gcgttgccgt tctcgccggg
    43621 cggcaggatg tccgagcact gcccgccgca gtagtcggtg gtggggtccg cggcgtgcgc
    43681 ggccatcgcg cccggcgcca acagggtggc gccgagggcc agcagcgcgg cggcggccgc
    43741 ggttctcagg gtgccgatcc gcctgccgac gcgcgtgccg atccgtcgtg gggtccgtag
    43801 cggcatgtct gctccttccg gataccggtg cgcggaggtt accgccggta cggactcccc
    43861 ggaagatgaa catacgtcag cttttcgttt tctccggcgc tccatttggc gtgaacacga
    43921 cgatacgtgc gcacatcgcc cggacccgcg gggccgccgc cgtcacacgg cccgcagcac
    43981 gaacacgccc caccccaggt agcggcgctg gtactccaga tgggtacgcc ggctgtgggc
    44041 caggaactcg cgcatgtccg ccgcgtcccg gtggtccgcc ggcaccgccc gcagccagtc
    44101 cgagatcgcg aaccactgct cggcgacgta gcggtcccag ctgtccccgt cggccagcac
    44161 catctccacc agctccgtgc cggcggcctc gaaccggtcc agcgtgccca ccagcgaggt
    44221 gaagtcctcc ggctcgaacc ccatcgcctc gaacgcctcc ttgggcgccg gctcggtcag
    44281 gtacggctcg ccgaccagca tcagcccgcc cggccgcagc gcccgccgca gcaggtcgac
    44341 ggtgccgccg agcccgccgc cgatccacgt cgcccccacg caggacacga cgtcgaacgc
    44401 cgccggctcc gcctcgtacg cccccgcgtc gccgcgtacg aagtccaccc gctcggccac
    44461 ccccagctcc gcggcccgca gccgggccgc cgtcaggaac acctcgctca ggtcgacccc
    44521 gacgcccccg gtgccgtacc gctccgccca gcgggtcagc atctccccct tcccgcacgc
    44581 caggtcgagc tgccgctgcc cctccttcag gcggcagacc tcgccgagga gcatcagctt
    44641 ctcgtccgtg atggggttca ggatgcggtg cccggactcc gcgatctcgt gatggcgcag
    44701 gctcatgcga ctcctcggcc gtacaggccc ccggcggggg cagaacccgc gcatcgtgcc
    44761 tgatccgggg gcacgggtgc cagtcgatat cgcgcggccg gggaggaggt ggagccgcag
    44821 gcccggcagc cgggacgcct cggcggtccg ggcctgctcc cgggccggtc cggcggctcc
    44881 ccgccgtgag cccggcagga tccgccggac aggccctaac gccggtcgag ccgcagcagg
    44941 ctctccgccg tcgcgagcac ggcctcctcg cccggccggg gcgcccagcc cagcagccgt
    45001 ccggccttcg ccgcgctcgt gcggcggatc gggaccgggc gcgcggccgc ctggcccgcc
    45061 gggtccgcgt ccgccgggcc ggccccctgc gagacctcct ccgtcggcac ccgcgccccg
    45121 gccgcgccca accgctcctt gagcagcacc gcgacgtcgc gca
//
