LOCUS       NZ_CP068102            41856 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Rothia aeria strain FDAARGOS_1137 chromosome, complete genome.
ACCESSION   NZ_CP068102
VERSION     NZ_CP068102.1
KEYWORDS    RefSeq.
SOURCE      Rothia aeria
  ORGANISM  Rothia aeria
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micrococcales;
            Micrococcaceae; Rothia.
REFERENCE   1  (bases 1 to 2583917)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2583917)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 8.0.0, HGAP v. 4
            Genome Coverage                   :: 941.26x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016726365.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 16:41:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,276
            CDSs (total)                      :: 2,214
            Genes (coding)                    :: 2,202
            CDSs (with protein)               :: 2,202
            Genes (RNA)                       :: 62
            rRNAs                             :: 4, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 12
            CDSs (without protein)            :: 12
            Pseudo Genes (ambiguous residues) :: 0 of 12
            Pseudo Genes (frameshifted)       :: 2 of 12
            Pseudo Genes (incomplete)         :: 10 of 12
            Pseudo Genes (internal stop)      :: 2 of 12
            Pseudo Genes (multiple problems)  :: 2 of 12
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:52:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1159090
            Orig. end                         :: 1200946
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP068102.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41856
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..41856
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..26994
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26994
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16994](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16994)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    906..920
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            complement(1275..1574)
                     /db_xref="GeneID:93861575"
                     /locus_tag="I6I94_RS04795"
                     /old_locus_tag="I6I94_04795"
     CDS             complement(1275..1574)
                     /codon_start=1
                     /db_xref="GeneID:93861575"
                     /inference="COORDINATES: protein motif:HMM:NF018925.5"
                     /locus_tag="I6I94_RS04795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04795"
                     /product="DUF1440 domain-containing protein"
                     /protein_id="WP_236588949.1"
                     /transl_table=11
                     /translation="MHFTFAIFFAVLYCVVAEYWPKIKLWQGVAFGIVLDILFHVIIMP
                     AMGVVPAPWNQPFGEHFSEFFGHILWLWSIELVRRDLRNRITGEPDAEYPVTAR"
     gene            complement(1643..1978)
                     /db_xref="GeneID:93861576"
                     /locus_tag="I6I94_RS04800"
                     /old_locus_tag="I6I94_04800"
     CDS             complement(1643..1978)
                     /codon_start=1
                     /db_xref="GeneID:93861576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888504.1"
                     /locus_tag="I6I94_RS04800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04800"
                     /product="DUF2218 domain-containing protein"
                     /protein_id="WP_006888504.1"
                     /transl_table=11
                     /translation="MSEYPPAESLPVRQRAVVATERPARYVKQLGSHMGRKIDTAELPG
                     GLRLTFNRDGIFRGYGDLLIDEANNALIMEVRAEDEEKATNIAGVLDRHLVRFGERDEL
                     VVEFRRV"
     misc_feature    complement(2075..2090)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.84"
                     /tool="antismash"
     gene            2287..3759
                     /db_xref="GeneID:93861577"
                     /locus_tag="I6I94_RS04805"
                     /old_locus_tag="I6I94_04805"
     CDS             2287..3759
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888587.1"
                     /locus_tag="I6I94_RS04805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04805"
                     /product="NCS2 family permease"
                     /protein_id="WP_201620947.1"
                     /transl_table=11
                     /translation="MSSENTAAPQAPQTNTTQGALDRYFKITERGSTISAEIRGGLATF
                     FAMSYIVVLNPLIIGLVKDANGHALGVPQVAAVTALIAGIMTIAMGIYAKQPFAMAAGL
                     GVNALLATTILSTPNLTWPQIMGLVVWAGVLMTALVLTGFRTAVFEAVPESLKTAIVVG
                     IGFFIAFIGLVNAGIIRRTVDAAHTTVPVTFGVGGHLLGWPTVVFLVGLFLTIALFIRK
                     VRGAILYGVLASTVLSIILEAVFHIGSSKDNPTGWSLNVPAWGGGSALPDVSLLFSADM
                     FGAFGTIGGMAATMLIFTILISAFFDAMGTTVGLATEAGTIDKDGKIENIDRVLLVDAL
                     GSVAGGGTSSSANQIFVESATGIGAGARTGLANVVTGALFVGAVFLSPLVTIVPFEAVA
                     PAMVFVGFLMIRQAVHIDWQDWGLGIPAFMTIIFMPFAYSIADGIGAGFISYVFIRLVQ
                     GRGREVHWLMYVVSAVFLVFFSTGLINGFTHG"
     gene            3971..5440
                     /db_xref="GeneID:93861578"
                     /locus_tag="I6I94_RS04810"
                     /old_locus_tag="I6I94_04810"
     CDS             3971..5440
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005507244.1"
                     /locus_tag="I6I94_RS04810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04810"
                     /product="NCS2 family permease"
                     /protein_id="WP_126499528.1"
                     /transl_table=11
                     /translation="MSSENTAAPQAHKPNASGGALDRYFKITERGSSISAEIRGGLAAF
                     FAMSYIVVLNPLVIGTGADSAGNTLGVPQVAAVTALVAGVMTILMGVIAKQPFAMAAGL
                     GVNALLASTIATTPGLTWADIMGLVIIAGLIMTVLVLTGFRTAVFEAVPESLKTAIVAG
                     IGFFIAFIGLVDSGIIRRMPDAAGTTVPVSLGVGGHLLGWPTLVFIFGLFLTIALFIRN
                     VRGAILIGVVASTVLAIILEAVFHIGSSKGNPTGWSLNVPALNNFSFSAPDFSLIGSAR
                     FGAFGAIGVLGASLLVFAILLSVFFDAMGVSVGLATEAGTIDKDGKVENINEVLLVDAV
                     GSVVGGGASGSANQIFVESATGIGEGARTGLANIVTGVLFLVAIIASPLVTIVPFEAVA
                     PALVVVGFLMVRQAVHIDWQDWGLGIPAFMTIIFMPLSYSIANGIGAGFVSYAFIRLVQ
                     GRGREVHWLMYVVSAVFVIYFGMGIINGFTH"
     gene            complement(5581..6462)
                     /db_xref="GeneID:93861579"
                     /locus_tag="I6I94_RS04815"
                     /old_locus_tag="I6I94_04815"
     CDS             complement(5581..6462)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861579"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888449.1"
                     /locus_tag="I6I94_RS04815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04815"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_128087415.1"
                     /sec_met_domain="Abi (E-value: 9e-16, bitscore: 55.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLEKINVLYCVLAVYCVCFIFRIYEYFVLRTDQSFWGEAFVHKL
                     IGIGILGLVMQACSLGARSIGFTREHIMRPILAGLGFGAVVFAIAYVAEIALLPPTEFR
                     SLDVYVSTYAVSSNTGHQTALIFFVICLAGNVINVVMEEGVFRGLFQKLLGFRYSFMGA
                     AAISSVLFGLWHVIAPVRNYTDGTSSLGGAVMNALILMLTSAVVGFKFALMTRLTGSLY
                     MAMANHCANNVIVNLVHVTSVSGEDTLMFVRISIAQGLSFLVVAVWYLVASRRGSLPAA
                     GIEGAPASHPQP"
     misc_feature    complement(6425..6443)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 23.81"
                     /tool="antismash"
     gene            complement(6546..6938)
                     /db_xref="GeneID:93861580"
                     /locus_tag="I6I94_RS04820"
                     /old_locus_tag="I6I94_04820"
     CDS             complement(6546..6938)
                     /codon_start=1
                     /db_xref="GeneID:93861580"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6I94_RS04820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6I94_04820"
                     /product="hypothetical protein"
                     /protein_id="WP_037288454.1"
                     /transl_table=11
                     /translation="MRKLAVNICATTGISLILLAVIGLLSGGTYLYLVGVFQVLATNMM
                     IHVGMLLVSRMALKYPLLEALVDIALILVMICGSGLAFGWFSSTPLWILCILGIVMYGA
                     STALNILHMRREVQEINMLIVRRKFT"
     gene            complement(6935..7336)
                     /db_xref="GeneID:93861581"
                     /locus_tag="I6I94_RS04825"
                     /old_locus_tag="I6I94_04825"
     CDS             complement(6935..7336)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888519.1"
                     /locus_tag="I6I94_RS04825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04825"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_236588950.1"
                     /transl_table=11
                     /translation="MSIVYAQKDVRVSRIVDFVESVEQRIKCENGSTDIMVNASDIFYC
                     ESVKKTTFVHVAGNTYRTDHRLYDLAEKLQDCGFVRVSKSCILNINVLESVKPLFNSRM
                     EAILTTGDKVYINRTYLKNVKQALKGYGA"
     CDS             complement(7418..7501)
                     /gene="allorf_1166508_1166591"
                     /locus_tag="allorf_1166508_1166591"
                     /protein_id="allorf_1166508_1166591"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVNNLYGGGYFCSLVVSSCSLVDTHPA"
     CDS_motif       complement(7478..7501)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVNNLYGG"
                     /locus_tag="allorf_1166508_1166591_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(7418..7477)
                     /prepeptide="core"
                     /locus_tag="allorf_1166508_1166591_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="1895.1"
                     /monoisotopic_mass="1893.9"
                     /core_sequence="GYFCSLVVSSCSLVDTHPA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVNNLYGG"
                     /leader_location="[7477:7501](-)"
                     /alternative_weights="1913.2"
                     /alternative_weights="1931.2"
                     /alternative_weights="1949.2"
     gene            complement(7622..9997)
                     /db_xref="GeneID:93861582"
                     /locus_tag="I6I94_RS04830"
                     /old_locus_tag="I6I94_04830"
     CDS             complement(7622..9997)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861582"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888614.1"
                     /locus_tag="I6I94_RS04830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04830"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_128087413.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.8e-27, bitscore:
                     90.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFPAVLQAAATECGLGVGASVLQHYGRYQTISDLRLIAEPGREG
                     LSMLQVRNLLMAEGMDVGAYKANSLEQLRDIGKPAILHWNNSHYVVLVRIRKDRVHIMD
                     PATGMKVIPLQEAEGSFSGSVLVPTPRKDFKKKSRKVFQDWQLNTFFTKKMFAQYAVFV
                     VLLVITYSVTFAVPVVIQSVVDAQLRGHEDAILVATIGVVVGVAGYYLVSIARAAALAS
                     IVSSIGYQLLGGMFKRLLKLPLTYFALRSPGDILYRLSSVNTLRNFLSTNLTELVINIG
                     TMIVILVFIAQQSREILIITFVVLAVLMLIWFVTARPTSQALDAEYAHASEAQVVELDA
                     INTVASMKMTGSASSTYETWREAYKQSLASMRRRMVLQQGVLGSAASVVQLGGPLILLL
                     ASLPLVNQGVLTLGQAIATEGISAMLFSSISSTMFGIMNIIAVDRAVARIVDIQRYDPE
                     QDGGTITKLASSDIELENVNFTYPGGTQPVLSEVSITVPEGHDIALVGSSGSGKSTLAM
                     LLCSLYSPVSGTIRMGGINVQDYSLDALRSHIGYVPQQLQTRGGTLYENLTAGLDDGRT
                     REEIEADVLSMGILDFVKGLPMGFDTIMSSDGENFSGGQRQRIAIVTALLRRPRILVLD
                     EATSALDTTTERQVTELIARYKCTKVVVAHRLSTIRNAQRIIVLEGGRIIQSGSHDELI
                     RVPGRYRDLYYLEDPESIAQEIRAHEAPQAQGKPQAQEPQDEQREYEESLYDHMAWVGV
                     ESAPRFRCRTSFWSSGSRYREATAARMHKAADNSRWLG"
     gene            complement(10001..13060)
                     /db_xref="GeneID:93861583"
                     /gene="lanM"
                     /locus_tag="I6I94_RS04835"
                     /old_locus_tag="I6I94_04835"
     CDS             complement(10001..13060)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861583"
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888423.1"
                     /locus_tag="I6I94_RS04835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04835"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_201620948.1"
                     /sec_met_domain="DUF4135 (E-value: 6.9e-54, bitscore:
                     180.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5e-29, bitscore: 98.2,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIRELLPELDEEQFQRLASYVSSTSLLERIGTTASEAPDSDFIV
                     RLSAPVSSALGPTAEPSMFHALIAQLAENERGNVEHAITSSGYAVTSQIHRLTNQFLDN
                     LTARLNNFYLRPLVAHIKKASAQGLLQADTPEGRYEDYCRRWHEELSDDFHASYPLLNR
                     IHQVTVQQFHAMIAEIFERVRTHENDIRELLNTTDAAPLQLESFGLPRTRYGGGRAGCL
                     LKFTQGTVVYKSRNVEGERAFWQIVQDLTQQGAPAMRAARVIQGEGYGFMEFIKAEEVD
                     FSGEDFLEASGRLAGLLYALQGKDMHAKNLIPLATGPVPIDLETVLHPIYILADDTPQP
                     PEGSAHLRKLRGISNSAFLPTRITRRDASLGYRDVGFLHGEQGNDPFNEVIVERPFRDD
                     AAARMNREPAPAPEENQEAASMVALVGDESSVEVLEERRLYEAARARAFARGFTQMHQW
                     ICEHREAMLEAVRANFTGLMLRALLQSTRFYTQILKMLSSPEALASQEVFATVGLRAAT
                     LSHNRPLDMVAAEAEALWRFDVPFFMHQTDGSDIVSFEGKPVGLSIKGSALEETLRHIA
                     TLDENDLEEQLQQIWAAFISPYPANTLANSPAELLSAGEDEQHERELCAAIADQLTGTL
                     RLGGSEQDSRTWLAPNPGLWQQHIGAWQTTVLGIDLYTGSVGPAMALAQAAHTLGNAEY
                     AQAAHRVLDPIAQDVFDKRLFSIPPETCDGVSGGEAGIALSLASAAEYLDDPRLKEAAI
                     MLGDRVAARMEQVEHPMPGYLDNQVGAATLLLGYNLATNRAALLEVLEKHALDIVAGRV
                     EENWWNVSGFAYGVSGSIFALARWGQEMPTPGRAQHAVKILLQRLNSFRCAEGWRAQLS
                     ERSGTGDAHTGGTWCSGSAGIALALAAVHVWMPEFSPRTELDRAVQYAFRTGTRSNLTL
                     CHGDLGTLEVLNWIIARVPDVPDAEDIRAAVKNGYGPSVIRATLDDKSSRYSLTPSLLV
                     GTSGVLSWLAHRLGGGRLYTPVIPDVSEDR"
     gene            complement(13102..13290)
                     /db_xref="GeneID:93861584"
                     /locus_tag="I6I94_RS04840"
                     /old_locus_tag="I6I94_04840"
     CDS             complement(13102..13290)
                     /codon_start=1
                     /db_xref="GeneID:93861584"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888468.1"
                     /locus_tag="I6I94_RS04840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04840"
                     /product="hypothetical protein"
                     /protein_id="WP_006888468.1"
                     /transl_table=11
                     /translation="MPKDITLLEEISDQELGQVNGGGSHGGGYYSSVGGGSYGGGYCGG
                     GCGGYGYGFGFWGGSFS"
     CDS_motif       complement(13225..13290)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPKDITLLEEISDQELGQVNGG"
                     /locus_tag="I6I94_RS04840_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13102..13224)
                     /prepeptide="core"
                     /locus_tag="I6I94_RS04840_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.20"
                     /molecular_weight="3622.7"
                     /monoisotopic_mass="3620.4"
                     /core_sequence="GSHGGGYYSSVGGGSYGGGYCGGGCGGYGYGFGFWGGSFS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPKDITLLEEISDQELGQVNGG"
                     /leader_location="[13224:13290](-)"
                     /alternative_weights="3640.7"
                     /alternative_weights="3658.8"
                     /alternative_weights="3676.8"
                     /alternative_weights="3694.8"
     misc_feature    complement(13478..13494)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.72"
                     /tool="antismash"
     misc_feature    13647..13663
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 24.59"
                     /tool="antismash"
     gene            complement(13986..16994)
                     /db_xref="GeneID:93861585"
                     /gene="lanM"
                     /locus_tag="I6I94_RS04845"
                     /old_locus_tag="I6I94_04845"
     CDS             complement(13986..16994)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861585"
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888544.1"
                     /locus_tag="I6I94_RS04845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04845"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_201620949.1"
                     /sec_met_domain="DUF4135 (E-value: 4.5e-63, bitscore:
                     210.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.7e-32, bitscore:
                     109.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIRELLPELDDEQFQQLVSDVSDVSLLDRLDTTSDSPPVGRPSA
                     PVPSALGPTAEPAMFYTLFAWLFESEYKRVVQAVRASHYVDKEHFPNIVGGLLDEFTVR
                     LANFYIRPLVAHIKKVSSEGLLQGDTPEERYIDYCRRWPKDFMDGFYTNYPLLRRVHSI
                     IVHQFHAIAAELFERIQAQESGIRELLGAQNAEPLTLESLTMAGDYHNGGRTGCLLVFS
                     QGTVAYKPRSVDGERAFYRIVQKLAEQGAPRMRAARVVQGEDYGFMEFIEREDVDFTAE
                     KFLESSGQLSALFYALLGKDMHEENLIPTSEGAVPIDLETILHCSHLLNDGKADIPDNS
                     ALLHKERGICTSALLPTRLVRKDPSKGYVDIGFIRGEQGANPFKGTVIEQPFRDDAIVR
                     SVRYSDLGGPQQGTDPDTHTLEKRRATEVARARGFVRGFEQMYRWVCEHRDAMQELVRS
                     ECAALTLRAVLQPTMQYEQLVRMLGSPEALSSKSVFATVALRTAAFDDDRSLELVLAEV
                     ESLWQLDIPFFKHRADRTAIMTPDGQEVGLGIKTSALEETLNHISHMDEDDLDEQLNQI
                     WSAFISPYPANTLADEPADIRQGRGGEREERELSTAIADRLAATVHSGTAPEDPWTWVS
                     PVPSSQQHHHGIWNTDVLQTDLYGGSVGIALALAQAAHVLGHQEYAETAHRVFDPLAET
                     ILSGEKSLKLPEYIRDMAFAGEPGIAFTLAGGARYLGDTRLKDAALELGNQVAARIAKV
                     EHPTPGYLSGHVGAATLLLGHELATDRQAPLAVLDRHAQDIIAGRIDDAWWAQSGFATG
                     MSSSIFALSRWSQDMPSPERARQAVATLLNRLDELDNGEYWQMRVPIGESAHDGTWCHG
                     SAGVALALAAVHCWLPELSNRASLDRAVRRSLQEGTKRNFTSCHGALGTLDVLEWVVSH
                     VPDVSNAEAVHDAVKNGYNVSLLRETLNDKSVRYSLTPSLMVGTSGVLLWLTRRAGDTH
                     LYTPIVPDSAEAH"
     misc_feature    17014..17023
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.08"
                     /tool="antismash"
     gene            complement(17024..17221)
                     /db_xref="GeneID:93861586"
                     /locus_tag="I6I94_RS04850"
                     /old_locus_tag="I6I94_04850"
     CDS             complement(17024..17221)
                     /codon_start=1
                     /db_xref="GeneID:93861586"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03949.1"
                     /locus_tag="I6I94_RS04850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04850"
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="WP_128087412.1"
                     /transl_table=11
                     /translation="MAKDTMFMEELTDQELEQVNGGCYSSCGYYGGSYGGSYGGSYCGS
                     GSSYYGGGYYYAAVGYGYSC"
     CDS_motif       complement(17156..17221)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKDTMFMEELTDQELEQVNGG"
                     /locus_tag="I6I94_RS04850_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17024..17155)
                     /prepeptide="core"
                     /locus_tag="I6I94_RS04850_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.70"
                     /molecular_weight="4213.4"
                     /monoisotopic_mass="4210.6"
                     /core_sequence="CYSSCGYYGGSYGGSYGGSYCGSGSSYYGGGYYYAAVGYGYSC
                     "
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKDTMFMEELTDQELEQVNGG"
                     /leader_location="[17155:17221](-)"
                     /alternative_weights="4231.4"
                     /alternative_weights="4249.4"
                     /alternative_weights="4267.4"
                     /alternative_weights="4285.4"
                     /alternative_weights="4303.5"
     CDS             17419..17490
                     /gene="allorf_1176509_1176580"
                     /locus_tag="allorf_1176509_1176580"
                     /protein_id="allorf_1176509_1176580"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVENRDLASSSPKYSAIKNCSRK"
     CDS_motif       17419..17448
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVENRDLASS"
                     /locus_tag="allorf_1176509_1176580_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       17449..17490
                     /prepeptide="core"
                     /locus_tag="allorf_1176509_1176580_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1427.7"
                     /monoisotopic_mass="1426.8"
                     /core_sequence="SPKYSAIKNCSRK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVENRDLASS"
                     /leader_location="[17418:17448](+)"
                     /alternative_weights="1445.7"
                     /alternative_weights="1463.7"
     CDS             17619..17804
                     /gene="allorf_1176709_1176894"
                     /locus_tag="allorf_1176709_1176894"
                     /protein_id="allorf_1176709_1176894"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLCALIALYYGHHITKWCDIKWKLRICESVKLFLSHNRSPISAFG
                     SSRCYPFFASSIEHPQ"
     CDS_motif       17619..17651
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLCALIALYYG"
                     /locus_tag="allorf_1176709_1176894_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       17652..17804
                     /prepeptide="core"
                     /locus_tag="allorf_1176709_1176894_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="5727.6"
                     /monoisotopic_mass="5724.0"
                     /core_sequence="HHITKWCDIKWKLRICESVKLFLSHNRSPISAFGSSRCYPFFA
                     SSIEHPQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLCALIALYYG"
                     /leader_location="[17618:17651](+)"
                     /alternative_weights="5745.6"
                     /alternative_weights="5763.6"
                     /alternative_weights="5781.6"
                     /alternative_weights="5799.6"
                     /alternative_weights="5817.7"
                     /alternative_weights="5835.7"
     CDS             complement(17689..17904)
                     /gene="allorf_1176779_1176994"
                     /locus_tag="allorf_1176779_1176994"
                     /protein_id="allorf_1176779_1176994"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MEIMMRTYCILPRWFDTVEGLARVAISLLQGRELIVGVLLRMQRM
                     DSIESFRKLILGSYCVIGTVLHSHIS"
     CDS_motif       complement(17731..17904)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MEIMMRTYCILPRWFDTVEGLARVAISLLQGRELIVGVLLRMQRMDSIESFRKLILGS"
                     /locus_tag="allorf_1176779_1176994_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17689..17730)
                     /prepeptide="core"
                     /locus_tag="allorf_1176779_1176994_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="1374.6"
                     /monoisotopic_mass="1373.7"
                     /core_sequence="YCVIGTVLHSHIS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEIMMRTYCILPRWFDTVEGLARVAISLLQGRELIVGVLLR
                     MQRMDSIESFRKLILGS"
                     /leader_location="[17730:17904](-)"
                     /alternative_weights="1392.6"
                     /alternative_weights="1410.6"
     misc_feature    complement(17815..17831)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.75"
                     /tool="antismash"
     gene            complement(18006..18518)
                     /db_xref="GeneID:93861587"
                     /locus_tag="I6I94_RS04855"
                     /old_locus_tag="I6I94_04855"
     CDS             complement(18006..18518)
                     /codon_start=1
                     /db_xref="GeneID:93861587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888379.1"
                     /locus_tag="I6I94_RS04855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04855"
                     /product="hypothetical protein"
                     /protein_id="WP_128087411.1"
                     /transl_table=11
                     /translation="MSDVISQESFDELALYFNGGGHLLTPDARRIAAERARILCACGLD
                     TLRQYTRRTGMTVHYYVAPYDTSDLLRTGADALALTGVRHELSRIKTPLIDAYILSGDL
                     TKFAPSWGLEPAPPTRANVILREVSALPRVLRLHVAADALHAYEAGAAGESARKAAQRI
                     LSELCSS"
     gene            18778..19266
                     /db_xref="GeneID:93861588"
                     /locus_tag="I6I94_RS04860"
                     /old_locus_tag="I6I94_04860"
     CDS             18778..19266
                     /codon_start=1
                     /db_xref="GeneID:93861588"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6I94_RS04860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6I94_04860"
                     /product="hypothetical protein"
                     /protein_id="WP_236588951.1"
                     /transl_table=11
                     /translation="MNSFNQLAAYIDDRTIAISPDARRRAKERAQVLAHTGLKALERYQ
                     ERSGMKVHYFRADPSNLEKLRHESALQMTGVSHDISEVYSSFTDAYVKTWDLETVVYKY
                     RLEPRLSVREANVLLREVEELPHIYSLHIALDLLDLRDARSRSEAERLLGKVLHEPHH"
     gene            complement(19521..19898)
                     /db_xref="GeneID:93861589"
                     /locus_tag="I6I94_RS04865"
                     /old_locus_tag="I6I94_04865"
     CDS             complement(19521..19898)
                     /codon_start=1
                     /db_xref="GeneID:93861589"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6I94_RS04865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6I94_04865"
                     /product="hypothetical protein"
                     /protein_id="WP_128087410.1"
                     /transl_table=11
                     /translation="MRIILFENFCERVFMSWFGKKQPNSKITWEGLTEFSVPGTNTGLD
                     LHPHFLAAQVAENRGWRFDYNGSIYEEQDNGSPLLVAEDIHELASFGEKNSWFKYSDRG
                     SRFIHWSLVSESLEAAKYPLS"
     cand_cluster    19530..41856
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    19530..41856
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[29529:31856](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(29530..31856)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="2"
     misc_feature    19875..19888
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    complement(19924..19937)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.71"
                     /tool="antismash"
     misc_feature    19924..19938
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.44"
                     /tool="antismash"
     misc_feature    complement(19927..19943)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.12"
                     /tool="antismash"
     gene            complement(19942..20379)
                     /db_xref="GeneID:93861590"
                     /locus_tag="I6I94_RS04870"
                     /old_locus_tag="I6I94_04870"
     CDS             complement(19942..20379)
                     /codon_start=1
                     /db_xref="GeneID:93861590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398386.1"
                     /locus_tag="I6I94_RS04870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04870"
                     /product="YchJ family protein"
                     /protein_id="WP_128087409.1"
                     /transl_table=11
                     /translation="MSETILYDPQTRCSCTSGEIYGACCGRYLGEFAASGTLNAPTPLA
                     LMRSRFTAFALHDAPYLLASWHPHTRPAELTLDETLRWYRLDILGSSGGPFDAAGTVEF
                     AAYYRSVPGTPAKEHVKGTMQEKSRFEKVNGTWYYLDGEVG"
     gene            complement(20517..21944)
                     /db_xref="GeneID:93861591"
                     /locus_tag="I6I94_RS04875"
                     /old_locus_tag="I6I94_04875"
     CDS             complement(20517..21944)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861591"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006498.1"
                     /locus_tag="I6I94_RS04875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04875"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_004006498.1"
                     /transl_table=11
                     /translation="MAEQKKRIAVNAFDMTCVGHQSFDLWRHPRSRATEYNTIKYWTDL
                     AQILEKGFFDGVFLADVVGIYDIYKNSAAPAIEGGAQVPVNDPFMQISAMAAVTEHLGF
                     GVTSAVTYEQPYTLARKYASLDHLTNGRVGFNVVTSYLPSAAECQGLETQIEHDTRYEL
                     AEEFLDVCYKLWEGSWEDGAVVKDREKGIYADPAKVHPIQHKGKYFSVPGAGLTEPSPQ
                     RTPVIFQAGASSRGQKFSGKHAEVVFIGALRPDLTRIITDRIRDRAEENGRGRDEIKVF
                     AMLSIIVDETEEKAKAKYEEYRKYVNLESSQAIIGGWSGVDLSQFDEDEVLNYVKTESI
                     QSFLTPFTLQAKDKQWTRKDIAEHCTIGGMGEVIVGDPQQVADELERWIDEGGLDGINL
                     AYHVSPGSFEDFIEFVVPELQKRGRYRTSYEGETLRESLFGKGQTKVADSHPAAKYRGA
                     YVGKPSTADTPARAIAN"
     CDS             complement(21945..22097)
                     /gene="allorf_1181035_1181187"
                     /locus_tag="allorf_1181035_1181187"
                     /protein_id="allorf_1181035_1181187"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPQMMIWLQGTRSKYGANAPPAQLGTPRRPPPIRRRRAGCRNTRT
                     FAKGT"
     CDS_motif       complement(22047..22097)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPQMMIWLQGTRSKYGA"
                     /locus_tag="allorf_1181035_1181187_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21945..22046)
                     /prepeptide="core"
                     /locus_tag="allorf_1181035_1181187_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="3599.1"
                     /monoisotopic_mass="3597.0"
                     /core_sequence="NAPPAQLGTPRRPPPIRRRRAGCRNTRTFAKGT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPQMMIWLQGTRSKYGA"
                     /leader_location="[22046:22097](-)"
                     /alternative_weights="3617.2"
                     /alternative_weights="3635.2"
                     /alternative_weights="3653.2"
     CDS             21970..22074
                     /gene="allorf_1181060_1181164"
                     /locus_tag="allorf_1181060_1181164"
                     /protein_id="allorf_1181060_1181164"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFLHPARRLLIGGGLLGVPSCAGGAFAPYLLRVP"
     CDS_motif       21970..22008
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFLHPARRLLIGG"
                     /locus_tag="allorf_1181060_1181164_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22009..22074
                     /prepeptide="core"
                     /locus_tag="allorf_1181060_1181164_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="2040.4"
                     /monoisotopic_mass="2039.1"
                     /core_sequence="GLLGVPSCAGGAFAPYLLRVP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFLHPARRLLIGG"
                     /leader_location="[21969:22008](+)"
     CDS             22029..22169
                     /gene="allorf_1181119_1181259"
                     /locus_tag="allorf_1181119_1181259"
                     /protein_id="allorf_1181119_1181259"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MCRWRIRAVLASCSLKPDHHLGHPATGEGCRPASQSFTPGLIILA
                     F"
     CDS_motif       22029..22064
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCRWRIRAVLAS"
                     /locus_tag="allorf_1181119_1181259_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22065..22169
                     /prepeptide="core"
                     /locus_tag="allorf_1181119_1181259_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="3468.9"
                     /monoisotopic_mass="3466.8"
                     /core_sequence="CSLKPDHHLGHPATGEGCRPASQSFTPGLIILAF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCRWRIRAVLAS"
                     /leader_location="[22028:22064](+)"
                     /alternative_weights="3487.0"
                     /alternative_weights="3505.0"
                     /alternative_weights="3523.0"
     regulatory      complement(22048..22157)
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00634"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00634"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class IV; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     CDS             complement(22150..22269)
                     /gene="allorf_1181240_1181359"
                     /locus_tag="allorf_1181240_1181359"
                     /protein_id="allorf_1181240_1181359"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTKYCMIHAKYYGAESQKLMFVIYCSPHLRGDTLRTQGL"
     CDS_motif       complement(22228..22269)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTKYCMIHAKYYGA"
                     /locus_tag="allorf_1181240_1181359_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22150..22227)
                     /prepeptide="core"
                     /locus_tag="allorf_1181240_1181359_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="2821.3"
                     /monoisotopic_mass="2819.5"
                     /core_sequence="ESQKLMFVIYCSPHLRGDTLRTQGL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTKYCMIHAKYYGA"
                     /leader_location="[22227:22269](-)"
                     /alternative_weights="2839.3"
                     /alternative_weights="2857.3"
                     /alternative_weights="2875.3"
     regulatory      22333..22415
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            22420..23241
                     /db_xref="GeneID:93861592"
                     /locus_tag="I6I94_RS04880"
                     /old_locus_tag="I6I94_04880"
     CDS             22420..23241
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861592"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888518.1"
                     /locus_tag="I6I94_RS04880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04880"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_128087408.1"
                     /transl_table=11
                     /translation="MTQNHHTQLPANAQTITFDAVSQSFPQSGKNTHEVLREVSFTAAA
                     GEIISVIGASGCGKSTLLRAAAGLNRITGGQVRIDNTPVSGLDQRVAIGFQEPRLLPWR
                     TVADNVALGLPQGTPKTRAQERIRELLRLVGLADYATHRPKEISGGMAQRVSLARALAR
                     EPGVLLLDEPFGALDALTRIKMQDLLLDIHRQDPTTVLLVTHDVEEALYLSDRVIVLGK
                     PAPDASATITRVVTISDAHPRDRASKELTALRAELLTELGVEKADTALVPA"
     gene            23360..24409
                     /db_xref="GeneID:93861593"
                     /locus_tag="I6I94_RS04885"
                     /old_locus_tag="I6I94_04885"
     CDS             23360..24409
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0042918 - alkanesulfonate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888401.1"
                     /locus_tag="I6I94_RS04885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04885"
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_128087407.1"
                     /transl_table=11
                     /translation="MTAITRAEALKGLLAFSALTTVLAGCAGEGAGNPGAGSAKGKDTV
                     TVDYATYNPLSLVIKKKGWLEKALQEKGKKLEWVKSAGSNKANEALRSGNIDVGSTAGS
                     AALLARANGSPIKVIDLYSQPEWSALVTTKNSNIHAVSDLKGKSVAVTKGTDPYFLLLQ
                     ALKQEGIAAKEVTIQNLQHADGRTALDNGQVNAWSGLDPIMASAEIESHDVLFYRNLDF
                     NTYGFLNATEQFLTDNPDAAQTIVNVYEYARKWALENTAEATQILADESGIKLETAKLV
                     MERTHLNIDPIPGDKQVQVLKGVGPILVESGDVPNQSDIDKALSSIVDDTYAKKADSAA
                     VENVKKTVS"
     gene            24412..25344
                     /db_xref="GeneID:93861594"
                     /locus_tag="I6I94_RS04890"
                     /old_locus_tag="I6I94_04890"
     CDS             24412..25344
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861594"
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888349.1"
                     /locus_tag="I6I94_RS04890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04890"
                     /product="ABC transporter permease"
                     /protein_id="WP_128087406.1"
                     /transl_table=11
                     /translation="MSVTLDKISNAPELSDTPKHTKSAAAETAAARTAAASTAAGRTQL
                     ASSHRGQPRPRRALPLGAKHYVGLILPAALIMLWYVLSTAGVFTAVQLPAPTRVIAAGT
                     ELAQRGELATHLVISTQRVVLGFSIGAVLGLFLGAIIGLWGPARIAAAPTIGALRAVPS
                     LAWVPLLLLWIGIGENSKVTLVAIGAFFPVYTTVSAALAHVDPKLVEAARAFGYRGVKL
                     FTTVQLPAVLPSVVSGLRLALAQAWLFLVAAELLGASMGLGYLLTDSQNNGRTDRLLLA
                     IVLLAVLGKLTDALIGVFERWVKAKYPSN"
     gene            complement(25444..26535)
                     /db_xref="GeneID:93861595"
                     /locus_tag="I6I94_RS04895"
                     /old_locus_tag="I6I94_04895"
     CDS             complement(25444..26535)
                     /codon_start=1
                     /db_xref="GeneID:93861595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005509195.1"
                     /locus_tag="I6I94_RS04895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04895"
                     /product="C4-dicarboxylate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_236588962.1"
                     /transl_table=11
                     /translation="MKSARLFAATVVLIAAGAVPASASTINTYDTDGDGIPNAWEISGY
                     DADGDGTVDVDYPGMGANPYRKDIFVEMDYMPGELATEADLDRITEVFASLPLRNPDGT
                     RGVSIHLDAGPARSAKYNLGGGNEIPHQKLNGMGDWAALKNRHFASARDAGFHYMIWGD
                     YYGNTSSSGLGFTGARGFIVTVGHTYWRGASSDIRVGTFIHELGHNLGLRHGGADEENY
                     KPNYLSIMNYEYQLSGVPRAGGKNYFGYSTHEHMPLDEKNLDERRGLGANAYGYLCKGK
                     PAHRNVDFNKNGVIDAQPVAADVNGNRRMSTLRAKSDMKTLRFAASATSQGVTSTPRTD
                     PDEVEVDYNEVTAEFARERGLLP"
     CDS             26573..26689
                     /gene="allorf_1185663_1185779"
                     /locus_tag="allorf_1185663_1185779"
                     /protein_id="allorf_1185663_1185779"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNEIQLIGAPQPPPTRGTRGALRRAPARKCIKIRYVRG"
     CDS_motif       26573..26599
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEIQLIGA"
                     /locus_tag="allorf_1185663_1185779_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       26600..26689
                     /prepeptide="core"
                     /locus_tag="allorf_1185663_1185779_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="3236.8"
                     /monoisotopic_mass="3234.9"
                     /core_sequence="PQPPPTRGTRGALRRAPARKCIKIRYVRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEIQLIGA"
                     /leader_location="[26572:26599](+)"
                     /alternative_weights="3254.9"
     misc_feature    26698..26712
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.39"
                     /tool="antismash"
     gene            26829..27689
                     /db_xref="GeneID:93861596"
                     /locus_tag="I6I94_RS04900"
                     /old_locus_tag="I6I94_04900"
     CDS             26829..27689
                     /codon_start=1
                     /db_xref="GeneID:93861596"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6I94_RS04900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6I94_04900"
                     /product="transcriptional initiation protein Tat"
                     /protein_id="WP_201620952.1"
                     /transl_table=11
                     /translation="MTHVPFRGGLTRRRALAGAAWSAPAVAASATAPAYAASDQVVAVD
                     YGVFTQAFNTTMDNPNSTFFGLDSYHGQLTDTRASRTTKWEGLLAAGGGTFTPGGSVGN
                     GLYGGAGLWFAAPHTASGEYTGTTTLRTGARFSIKYTFTFADEIQTRPPLLWEDGEQQQ
                     VAALAQSAGGARSNNPRLAAFNGAGFTAVFRESDSYGTEWRGTLDIVTAEDAVASAEGM
                     QVFNQVLLSQVPVYYDQVGESFSLRTTVTVVDATLLLEPVNSAAPSEQNIAGLSASATI
                     THSPA"
     gene            complement(27705..29369)
                     /db_xref="GeneID:93861597"
                     /locus_tag="I6I94_RS04905"
                     /old_locus_tag="I6I94_04905"
     CDS             complement(27705..29369)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861597"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="I6I94_RS04905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04905"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_201620953.1"
                     /transl_table=11
                     /translation="MSLTSSAASLLQPLIVNDLVDSAGSAQGIGYLPVLIILVLIIGAI
                     LNGVQQYFIQKVAESVARDARTQLVRKILRIPLDALEKYTKGDVLSRVINDTMLLRRCL
                     TEGFVQSFVGVFTLIGAVIGMFFIDPLLLAISAVISLLAVVSVTMATSKVEKSSAQMQQ
                     AVGELSSDVSSVLEASSLVRTENAAGHQFKRLQQKVDNAWLKGIGVARLVALITPISAV
                     AMQITFLVVLGVGGVRVANGIITVGNLVSFVMFLVMMIMPLGYIFGTMSNIAEASGGIT
                     RIQEILGIPDEYPEQLDTYHENRDIRSILLDNVSFKYGAEPEEGASPYLISGMTLSIAP
                     GEKIAIVGPSGSGKSTLLRLIARLYEISGGNLLYSGTASSDISIPAVRAKIGLVQQESP
                     LILGTLLDNVYISGRGTDSAAAHRILKDLGLEKVLERSGHGVDLNIGGSGTSLSGGEKQ
                     RLAIARVILKNPQVYLLDEFTSQLDGISEELVVSVLNNNAAPESTMIMVAHRMSTVVNA
                     DMIYVMDHGRIVAQGTHDILMEFSPLYRELVSNQLIH"
     gene            complement(29530..29946)
                     /db_xref="GeneID:93861598"
                     /locus_tag="I6I94_RS04910"
                     /old_locus_tag="I6I94_04910"
     CDS             complement(29530..29946)
                     /codon_start=1
                     /db_xref="GeneID:93861598"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="I6I94_RS04910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04910"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_128087402.1"
                     /sec_met_domain="PF13471 (E-value: 6.6e-19, bitscore: 65.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDNPTTATDAHTVSSIKARLAVCAAKIIARLPVTVIVRLLKMFR
                     PLQKSSSIQQALAVDAKVREVSPLCRGERGCLARSISTYLLLSLMRRKVVWASGFRVKP
                     FLAHAWVTVEGEPINEHHDVQGFVTVASTNPEAR"
     gene            complement(29939..30241)
                     /db_xref="GeneID:93861599"
                     /locus_tag="I6I94_RS04915"
                     /old_locus_tag="I6I94_04915"
     CDS             complement(29939..30241)
                     /codon_start=1
                     /db_xref="GeneID:93861599"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="I6I94_RS04915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04915"
                     /product="PqqD family protein"
                     /protein_id="WP_236588963.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-10,
                     bitscore: 38.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.9e-08, bitscore: 29.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKRYASLPERFCIADGVKISGTESGIVVFVPTRSAYFQGNSTTE
                     HILDLVEQGRRNSEIIDSFIRQYTQSDPDEIREDLEGTLRELWTMGVLEKGEDHG"
     aSDomain        complement(29960..30199)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_I6I94_RS04915_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.50E-12"
                     /identifier="RREFam002.1"
                     /label="I6I94_RS04915"
                     /locus_tag="I6I94_RS04915"
                     /protein_end="94"
                     /protein_start="14"
                     /score="38.4"
                     /tool="antismash"
                     /translation="ADGVKISGTESGIVVFVPTRSAYFQGNSTTEHILDLVEQGRRNSE
                     IIDSFIRQYTQSDPDEIREDLEGTLRELWTMGVLE"
     gene            complement(30234..31856)
                     /db_xref="GeneID:93861600"
                     /locus_tag="I6I94_RS04920"
                     /old_locus_tag="I6I94_04920"
     CDS             complement(30234..31856)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861600"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="I6I94_RS04920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04920"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_172425646.1"
                     /sec_met_domain="Asn_synthase (E-value: 6.8e-27, bitscore:
                     92.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELYTTSGNVQKISHFLRSSSNNITVRPLPTHEASASNTDSTAG
                     SELVSSVSRHRSVYRSKLGPVDLLSTSVKPLVDALNPAINMSRVALGLCRNPPGWVRRV
                     SYWENIMALPPATTVCEDEHGSVQNTSYFADALSLQDSTLSFSDVSQHVYTVLNSVLRR
                     LAEGRTHVSADLSGGVDSTVISVLLAAQNVPFTAFHAGTDDKDNRDTQLAQKIAEHFAI
                     DLIKLDSFTKSTAGFTIPDELRGFSEAPRAWHANLPHLTALVRSARERGSSIHCLGIGG
                     DELFEPMPVQALLYFKQGEKMRAIKAISSVAAAARWPKVSTLRAAFSPETKQRELQRRL
                     TRRGQNIPENIDAFSWFPNFTLPSWLSEEATEQVIELMRATPIPPEEEELDKYRFHIYG
                     SLEFQGEVLRGMNEYFSETGLEFAAPYLEDDMIRSSLVYPGVLSGHGMSKPVILEAMKG
                     TLPEFFYRDIYKSDYSFDLYQDYERSKENFLKMIGDSLLAELNLVDIDTVRTIANSPLG
                     SSETLYDFERMTHMEVWLRENYV"
     misc_feature    32062..32074
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            complement(32455..32622)
                     /db_xref="GeneID:93861601"
                     /locus_tag="I6I94_RS04925"
                     /old_locus_tag="I6I94_04925"
     CDS             complement(32455..32622)
                     /codon_start=1
                     /db_xref="GeneID:93861601"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6I94_RS04925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6I94_04925"
                     /product="hypothetical protein"
                     /protein_id="WP_157769145.1"
                     /transl_table=11
                     /translation="MYTKAQLTRLGSFEEATHGWFWGSYRDIFGALRGPNSGFEGGGGF
                     TGGGVSGGSW"
     misc_feature    complement(32710..32727)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    complement(32750..32767)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
     misc_feature    complement(32779..32797)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.97"
                     /tool="antismash"
     misc_feature    complement(32841..32854)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.27"
                     /tool="antismash"
     misc_feature    32847..32861
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.92"
                     /tool="antismash"
     misc_feature    complement(32856..32870)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    32858..32871
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    33021..33033
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(33140..33149)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(33279..33629)
                     /db_xref="GeneID:93861602"
                     /locus_tag="I6I94_RS04930"
                     /old_locus_tag="I6I94_04930"
     CDS             complement(33279..33629)
                     /codon_start=1
                     /db_xref="GeneID:93861602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888509.1"
                     /locus_tag="I6I94_RS04930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04930"
                     /product="VOC family protein"
                     /protein_id="WP_006888509.1"
                     /transl_table=11
                     /translation="MAVKRIVTNLAADKPESAAAFYRDILGLELLMDHGWIQTYGNAET
                     TTVQVSIASEGGSGTPVPDLSVEVDNLDEILARIHTAGITLEYGVAEEPWGVRRFFVRD
                     PLGNLVNILQHM"
     misc_feature    33787..33802
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     regulatory      33935..34051
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            34057..36204
                     /db_xref="GeneID:93861603"
                     /locus_tag="I6I94_RS04935"
                     /old_locus_tag="I6I94_04935"
     CDS             34057..36204
                     /NRPS_PKS="Domain: AMP-binding (87-575). E-value: 8.1e-94.
                     Score: 306.4. Matches aSDomain:
                     nrpspksdomains_I6I94_RS04935_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:93861603"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888461.1"
                     /locus_tag="I6I94_RS04935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04935"
                     /product="AMP-binding protein"
                     /protein_id="WP_201620954.1"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-54, bitscore:
                     181.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLPSPFSFTNPLAPTPNPAHESDEARVAFWEKQAERLSWGKAWD
                     NAHTFQKPQVIGTDAEGIEEYSVPEIKWFEGGKLNVAYNCVDRHVEAGRGDKVALYFEG
                     EPGDREAITYAELQRRIARAANGLLKLGVRKGDRVVIYLPVIPETIIFTLACARIGAIH
                     SLVFGGFSAEALKFRVEDTGAKVLITTDGQNRRGKVVPVKVNADEACSGENNIEHVIVV
                     DRTSAADPVAHAQVPWTAGRDIWYHDLVDDQPDTHEYELHDAEDPLFIIYTSGTTGKPK
                     GLVHTMAGYLVQTAYTHALLYDLLPDYVDDDGVLRPDELSAVNDPAKVESTVHWCTADL
                     AWVTAHTYEIYGPLVNGVTEVIFEGTPNTPHYGRHFEVIERYGVTNYYTAPTLIRSLMG
                     AFPDGPEPGKYDFSTVRLLGSVGESINPQAWKWLRKHVGGGTASFIDTWWQSETGSTIC
                     SPRPHDPAFAPEGTFPEGTPHCTPLPGCATREVPGVSVRVVDEHGDLVEPGKQGFIVVD
                     KIGPSMARTVWGDPQRYLNSYWKHYGTRGWFLAGDGAKVDDEGNVYILGRIDDVINISG
                     HRLSTIEIESALVTHPAVVEAGVCPVEDELTGHQAVAYVTLTDEGRALTEDELKAALTE
                     HVREHIGPIAKPKDVVAVADIPKTRSGKITRRLLGELYQGHKLGDISSLQNEEALGAIA
                     QVLVDTGRVNPDAFTEEQAAA"
     aSDomain        34318..35781
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6I94_RS04935_AMP-binding.1"
                     /evalue="8.10E-94"
                     /label="I6I94_RS04935_AMP-binding.1"
                     /locus_tag="I6I94_RS04935"
                     /protein_end="575"
                     /protein_start="87"
                     /score="306.4"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="RHVEAGRGDKVALYFEGEPGDREAITYAELQRRIARAANGLLKLG
                     VRKGDRVVIYLPVIPETIIFTLACARIGAIHSLVFGGFSAEALKFRVEDTGAKVLITTD
                     GQNRRGKVVPVKVNADEACSGENNIEHVIVVDRTSAADPVAHAQVPWTAGRDIWYHDLV
                     DDQPDTHEYELHDAEDPLFIIYTSGTTGKPKGLVHTMAGYLVQTAYTHALLYDLLPDYV
                     DDDGVLRPDELSAVNDPAKVESTVHWCTADLAWVTAHTYEIYGPLVNGVTEVIFEGTPN
                     TPHYGRHFEVIERYGVTNYYTAPTLIRSLMGAFPDGPEPGKYDFSTVRLLGSVGESINP
                     QAWKWLRKHVGGGTASFIDTWWQSETGSTICSPRPHDPAFAPEGTFPEGTPHCTPLPGC
                     ATREVPGVSVRVVDEHGDLVEPGKQGFIVVDKIGPSMARTVWGDPQRYLNSYWKHYGTR
                     GWFLAGDGAKVDDEGNVYILGRIDDVINIS"
     CDS_motif       34861..34914
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6I94_RS04935_0001"
                     /evalue="5.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="I6I94_RS04935"
                     /protein_end="286"
                     /protein_start="268"
                     /score="22.0"
                     /tool="antismash"
                     /translation="FIIYTSGTTGKPKGLVHT"
     CDS_motif       35749..35811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6I94_RS04935_0002"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="I6I94_RS04935"
                     /protein_end="585"
                     /protein_start="564"
                     /score="14.4"
                     /tool="antismash"
                     /translation="LGRIDDVINISGHRLSTIEIE"
     gene            complement(36331..38073)
                     /db_xref="GeneID:93861604"
                     /locus_tag="I6I94_RS04940"
                     /old_locus_tag="I6I94_04940"
     CDS             complement(36331..38073)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861604"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888609.1"
                     /locus_tag="I6I94_RS04940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04940"
                     /product="MDR family MFS transporter"
                     /protein_id="WP_128087399.1"
                     /transl_table=11
                     /translation="MAEEAAPKKRPHTPSIEHAAEKPWVAMWSLVIGFFMILLDTTIVT
                     VALPHMQNELNASLSAVIWVTSAYLLAYAVPLLITGRLGDRFGQKQMYLLGMVVFTLSS
                     LWCGLSPNVEMLIVARVVQGIGASLMTPQTMSIITLMFPPHKRGVAMSVWGAAAGIASL
                     VGPIAGGLLVDGPGWTWIFFINIPIGVIGIYLAVRNIPHFPSKQHNFDWLGVVLSAIGL
                     FLMVFGIQEGSTYDWGIITESLWGTGIPVSVWGMIIAGIIVFTLFIVWQAVNRKEPLVP
                     LGLFKDRNFSVSNIAIAAMGAHTLTLAFPTTIYFQQVRGMSPTQAALMTAPLALFSGAL
                     SPLVGKRLGTSNPKWYAVSGFALLVVGFIVLRALMTADQSLALLLVPFAILGIGNSMIW
                     GPLAVTATRNLPPRLAGAGSGVYNETRQVASVLGSAGIATFMGGLITEQVTQAMQRMRP
                     AGAGAGGGAMSAPAVSGEGMSGGQVPDFLREPIATAMNDSLILALALAAVGMVACLFFA
                     KPVDKGAWASGQNVSDAPSSENTSTKNSSAENPGEVSSAEGSKATGESDPEPSDKGAET
                     GSKP"
     gene            38370..39062
                     /db_xref="GeneID:93861605"
                     /locus_tag="I6I94_RS04945"
                     /old_locus_tag="I6I94_04945"
     CDS             38370..39062
                     /codon_start=1
                     /db_xref="GeneID:93861605"
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888543.1"
                     /locus_tag="I6I94_RS04945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04945"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_128087398.1"
                     /transl_table=11
                     /translation="MAVVTIIGGHGKVALLAEPLLVERGHTVNALIRRPEQSEDIVTRG
                     ANPVVTDITALSTEEMVKLLTELGTEVLVWSAGAGGVGGPERTYAVDRDAAIRSMDAAR
                     LAGIKRYVMVSYLGAGSGHGIDPDNSFYAYAESKAIADEHLRGSGLDYTILGPGMLTLE
                     EAGGITLGVEPAHTPGAESNTPRATVAQVLAAVLEDPSTVGKALPFIGGPTPIAQALAS
                     APNSNKLR"
     gene            39171..39488
                     /db_xref="GeneID:93861606"
                     /locus_tag="I6I94_RS04950"
                     /old_locus_tag="I6I94_04950"
     CDS             39171..39488
                     /EC_number="3.6.1.7"
                     /GO_function="GO:0003998 - acylphosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005509193.1"
                     /locus_tag="I6I94_RS04950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04950"
                     /product="acylphosphatase"
                     /protein_id="WP_128087397.1"
                     /transl_table=11
                     /translation="MGFFSYFTDKTAPEPAEAQLTAYVSGRVQGVGFRWWCAGTAKPMG
                     LSGYAENLDDGRVKVIAQGTRASCEHLLDALNSGDTAGHVDFVDATFSDPQGTFKGFGI
                     R"
     gene            39622..40959
                     /db_xref="GeneID:93861607"
                     /locus_tag="I6I94_RS04955"
                     /old_locus_tag="I6I94_04955"
     CDS             39622..40959
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398372.1"
                     /locus_tag="I6I94_RS04955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04955"
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="WP_201620955.1"
                     /transl_table=11
                     /translation="MTRYRWGITGACILFLAGVIVYNLREFLAYDYLVYYAGGKSVNWF
                     LDYPSNLYDLDILRETVRAENFRYIFGDSGLWLAFTYPPFASLLFIPASFLPLRVAIGL
                     HLAFFVPIAFYCAKVLRDYLAKRNSRLLFEKYLSPFSFIVLCAALILLSAPWRNNFLYG
                     QINPYLLVLILYDLLRPGTRIPRGVFIGIAAGIKLTPLAIGVLFLVRKEWKSIIALGVS
                     FAGTIAAGFAVLPQQSLTYWGSVIWDPSRVGNPISSNSMAIQGVLGRMTFQDGTVLKAL
                     YGIAAIALIAVIGYALRKMEQHNLYLSQISLAILVPVFISPISWFHHAVILPIFMVCAA
                     VDFLPLVARWRSRAGRILCYLCYALSSLMLINTLLDWGKLVVRFWRRVDFYPFTGRYPG
                     MDAHTLLLRAADEQPVMFVTSIPALALVVLVVLWAVLLRRPAESRQ"
     gene            complement(41071..41655)
                     /db_xref="GeneID:93861608"
                     /locus_tag="I6I94_RS04960"
                     /old_locus_tag="I6I94_04960"
     CDS             complement(41071..41655)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:93861608"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006489.1"
                     /locus_tag="I6I94_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6I94_04960"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_201620956.1"
                     /transl_table=11
                     /translation="MKIPELITEKFTLRPLREADLDELVQICTDPETVRWTTVPLNYTR
                     DDAQTFLTFTQRAAAAGRELTWAIDDSGVLAGAISLRLPEGSANAPGTYADLGFYTAAQ
                     MRGRGIMTDAVRTVLGFSFDPLGLGLDTIGWAALVGNAASERVAVKAGFTNITDETSTS
                     AARPDKYGNRKAVAVRQATMTRAQFAEIWRD"
ORIGIN
        1 gtaatcacgc ccttatcagc gtcgtagccg acctcgggca gttcagatcc gaaataacca
       61 atcgcgcggt acacagcctg cacggggtag tccacgaact cgccggtgcc ctcgataccg
      121 cccttaccgt caagcttatt gcgttccatg cggatgccca caaccttgcc gtcctcaccc
      181 agaatctcgt gcggggactg caggaagtgc aggtgcaggc ggcgcgatgc ggtctgctcg
      241 ccctcctcct ggtcggtaag ccaggtggtg agggtcttca tcatggtctt cacctggtta
      301 ttcgtctgaa tagcctcatc cgaagcctcg tcgaactcga agtcctcttc gtagagcaca
      361 atatcgacat cgcgggagtg tgaaagctcg cgcagctcca agggggtgaa cttgatctgc
      421 gcggggccgc ggcggccaaa gacgtgcaca tcggtcacgg gcgaagattt cagcccttcg
      481 tacacattct cgggaatttc ggtgacgagc agatcatcgg cgtgcttaga gagcacacgc
      541 gcaatatcca acgccacgtt accgttacca agcaccgcga tttccttcgc gttcagcggc
      601 caggtgcgcg ggtaatcggg gtgaccgtca taccacgaga cgaaatcggc ggcaccatag
      661 gaaccatcca ggtcgatgcc cttaatgggc aggggcgcgt catgaatagc gccggtcgcg
      721 aagataatgg cgtcgtagtg ctcgcgcagg tcggcaaggt tcaaatcctt accgtattcg
      781 acattgccga agaatcgaat atcaccgcgg tcaagcacct tgtgcagggc ggtaataatg
      841 cccttaatac gcgggtgatc gggcgccaca ccgtaacgaa tcagcccgaa gggagcgggg
      901 taacgatcaa aaatgtcgat agaaacctca acggctccag agcgtacttc ctcagatttg
      961 gtgatgaggt cagcggcgta aatgccagcg gggcctgcgc caataacagc gacgcgcagg
     1021 gggcgggtag cttcagacac gtatttttcc tttcaaagtt cgccccggta cacggttcag
     1081 gctggtgcgg cggcgagctc tctttttagt cctcgttcat tctaccgggc acagcggtta
     1141 ggatgggcta aaaagaggga aagcgagcaa tagctcatat atttttattc cttatatatg
     1201 gcaatacggc tgtgccccgc atgagacgct catgcggggc acagccgtat accggttacg
     1261 atacactcag tgatttagcg ggcagtcacc gggtactctg catcgggttc accggtgatg
     1321 cggttacgca ggtcgcggcg gaccagctca atcgaccaca accagaggat gtgcccaaag
     1381 aactcagaga agtgctcccc aaaaggctgg ttccacgggg cgggcacaac tcccattgcg
     1441 ggcataatga tgacgtggaa aagaatatca agcacaatgc cgaaagccac accctgccag
     1501 agcttaatct tgggccaata ttcagccacc acacagtaga gcaccgcaaa gaaaatagcg
     1561 aatgtgaagt gcactaggga aaatatctgg ggtatccgcc ctcatttttc cacggaggtg
     1621 ccgcagtata taaaacgtct gcctacaccc ttcggaactc aaccaccagc tcgtcacgtt
     1681 cgccaaagcg caccaggtgg cgatccagca cacccgcaat attagtggcc ttctcctcat
     1741 cctcagcacg cacctccata atgagggcgt tattagcttc atcaatcagc agatcgccat
     1801 agccacgaaa aataccatca cggttaaacg tcagccgcag accgcccggc agttcggcgg
     1861 tatcaatctt acggcccata tgcgaaccta gctgtttcac ataacgggct gggcgttcag
     1921 tagcaaccac ggcacgctgg cgtacaggca aagactcagc gggaggatac tcgctcacaa
     1981 ttcacctctc aaattctcgg tagtagccct accaatacgg aagttaaggt attcctcatc
     2041 ttaccagcca gcccaggccc cgcctcaccc tcactacccc actgcggtaa agcccaaaac
     2101 ctccaccgcg cgcccactca caggctgtac taccgcccct catcaagcaa ctagcgcaca
     2161 cgcgctgcta ccccctagaa taatgaggta acaagagcgt cacgccccgc acggctgacg
     2221 cttttcttat gcgcgccccc gaccggtggg cacgcaccct acgagagtat ctacggattc
     2281 aacgaaatgt cttctgagaa caccgcggct ccccaggcac cccaaaccaa cacaacgcag
     2341 ggcgccctgg accgttactt caaaattaca gaacgaggct caactatctc cgccgagatt
     2401 cgcggcggct tagcgacctt cttcgccatg agctatatcg tggtgctaaa ccccctcatt
     2461 atcggcctcg tgaaagacgc caacggccac gcgctcggcg tgccgcaggt ggccgctgtc
     2521 accgcgctta tcgccggaat catgacgatc gccatgggta tctacgcgaa acagcctttc
     2581 gcaatggcgg cagggctggg cgtgaacgca ctactggcaa ccactatcct cagcaccccc
     2641 aatctcactt ggccgcaaat tatggggctg gtcgtgtggg cgggtgtgct catgactgcc
     2701 ctcgtgctga ccggcttccg caccgccgtc tttgaggcgg tccccgagag cctcaaaacc
     2761 gcaattgtgg tgggtatcgg cttcttcatt gcctttatcg ggctggtcaa cgcaggtatt
     2821 atccgccgca ccgtagacgc cgcgcacacc accgtccccg tcaccttcgg cgtgggcggg
     2881 cacctgcttg gctggcccac cgtggtgttc cttgtcgggc tgttcctcac cattgcccta
     2941 tttattcgga aagtacgcgg ggccatccta tacggtgtgc ttgcctccac cgtgctgtca
     3001 ataatcctag aggccgtttt ccacattggc agcagcaaag acaacccgac cggctggtca
     3061 ctgaacgtac ccgcatgggg cggcggcagc gccctacccg atgtttcgct gctgttctca
     3121 gcagatatgt ttggggcgtt cggcaccatc ggcggtatgg ccgccacgat gctgatcttc
     3181 accatcctca tctcggcgtt cttcgacgcg atgggcacca ccgtgggcct agccaccgaa
     3241 gctggcacca ttgataaaga cggcaaaatt gagaacatcg accgtgtgct gctggtggat
     3301 gcgctcggct cagttgcggg cggtggcacc tccagctcgg ccaaccagat ttttgtggaa
     3361 tcggcaaccg gtattggtgc tggcgcccgc acgggcctgg cgaacgtggt caccggcgcg
     3421 ctctttgtgg gcgcggtctt cctctctcca ctggtgacca tcgtcccctt cgaggcggtc
     3481 gcccccgcca tggttttcgt ggggttcctc atgatccgcc aggccgtgca tatcgactgg
     3541 caggattggg gcctgggtat cccggcgttt atgaccatta ttttcatgcc gttcgcctac
     3601 tccattgccg acggtattgg tgcagggttc atctcctacg tcttcatccg cctggtgcag
     3661 ggtcgcgggc gcgaggtgca ctggctcatg tacgtggtat cggctgtttt cctggtgttc
     3721 ttcagcaccg gactcattaa cggtttcacc cacgggtaaa ggcagcttcc cagcattcca
     3781 tctgccggaa agtccgttac gggggcttag gcgccccggc ggcttttcgg caggtggatg
     3841 cgggagaaaa acaaaacacc tagaataggg tggtaacacc agcgctgaat cccgccgggg
     3901 ttcggcgctt ttcttattgt ggcgcaaacc cgcgcccacg tcccacgaga gtatctacgg
     3961 attcaacgaa atgtcttctg agaacaccgc ggctccccag gcacacaagc ccaacgcatc
     4021 gggcggcgca ctggaccgtt acttcaaaat cactgaacga ggctcatcta tttcagccga
     4081 gattcgtggc ggtctcgccg cgttcttcgc tatgagttat atcgtcgtcc tcaaccccct
     4141 ggtgatcggc accggcgcag actcggcggg aaataccctt ggcgtgccgc aggtcgccgc
     4201 ggtcaccgca ctcgtcgccg gcgtaatgac catcctgatg ggtgttatag ccaagcaacc
     4261 tttcgcgatg gcggcggggc tgggtgtgaa cgcactgctg gcctccacga tcgcaaccac
     4321 tcccgggctg acgtgggcag atattatggg cctggtgatt atcgctggtc ttattatgac
     4381 cgtgctggtg ctcaccggct tccgcaccgc cgtattcgag gcggtccccg agagcctcaa
     4441 aaccgcgatc gtggcgggaa tcggcttctt tatcgccttt atcgggctgg ttgattccgg
     4501 gattatccgc cgcatgccgg atgccgcagg aaccaccgtt cccgtctcgc tcggggtggg
     4561 cggtcaccta cttggctggc ctactctcgt gtttattttc ggccttttcc tcaccatcgc
     4621 cctgtttatt cgcaatgtgc gcggcgctat cctcattggc gtggtggcat ctaccgtact
     4681 ggcgatcatc ctagaagctg ttttccatat tggcagcagc aaagggaacc cgaccggctg
     4741 gtcgctcaac gttcccgcgc tcaataattt ttccttctca gcccccgatt tctcgcttat
     4801 cgggtctgca cgattcggcg cgttcggcgc tatcggcgtg ctgggtgcat ccttgctggt
     4861 gttcgctatt ctgctctcgg ttttctttga tgccatgggt gtttcggtgg gcttagcaac
     4921 cgaagcgggc accatcgata aggacggcaa ggtcgagaac attaacgagg tgctgctcgt
     4981 ggatgcggtc ggttccgtgg tcggcggcgg cgcatccggc tctgcgaacc agatttttgt
     5041 ggagtcggca actggtattg gtgagggtgc ccgcacgggt ctggcgaata tcgtcaccgg
     5101 cgtgctgttc ctggtggcga ttatcgcctc gccgctggtg acgattgttc cctttgaggc
     5161 cgtcgccccc gctctggtgg ttgttgggtt cctgatggtg cgccaggccg tgcatatcga
     5221 ctggcaagat tggggtctgg gtatcccggc gttcatgacc atcattttca tgccgttgtc
     5281 gtactcgatc gctaacggta ttggtgcagg gttcgtctcc tacgccttca tccgtctggt
     5341 tcagggccgc gggcgcgagg tgcactggct catgtacgtg gtgtcggcgg tgttcgtcat
     5401 ctacttcggc atgggtatta ttaacggttt cacgcactag cgtttactga aatcccgggt
     5461 atatatcggg tgtaaaaagg ctctttttga agagaagcgg cggaaaacta cgctttattc
     5521 gaaaagagcc ttttatacac ctatgggggg gtagatatgc gctcgaaaac gtcagaaatt
     5581 tcacggctgc ggatgtgacg cgggcgcccc ctcaatccct gccgcaggaa gactcccgcg
     5641 gcgtgaagcc accaggtacc atactgccac cacgagaaat gatagccctt gcgctatgga
     5701 gatccgcacg aacatcagcg tatcctcccc ggaaaccgac gttacatgca caagattcac
     5761 gatcacatta tttgcacagt ggtttgccat cgccatatag aggctgcccg tcaggcgcgt
     5821 catcagcgca aatttaaatc cgaccacggc tgatgtcagc atcaggatca gagcattcat
     5881 gaccgctccg cccaagcttg aggttccgtc cgtatagttc cgtacgggag cgatcacatg
     5941 ccacagacca aagagcaccg aagaaatggc tgcagcaccc ataaacgagt aacggaatcc
     6001 cagaagtttc tgaaaaagcc cgcgaaaaac tccttcttcc atgaccacgt tgatcacgtt
     6061 ccccgccaga cagatcacaa agaatatgag cgctgtctga tgccccgtat tgctgctgac
     6121 cgcgtaagtg ctcacataaa cgtcaaggga gcgaaattcg gtgggcggta aaagcgctat
     6181 ctcagcgaca taggcaatcg caaaaactac tgcgccgaaa cccagcccag caaggatagg
     6241 gcgcattatg tgctcacggg taaatccaat gctgcgggct ccaagagagc aggcctgcat
     6301 caccaaccct aaaattccta taccgatcag cttatgaacg aaggcttcac cccaaaaact
     6361 ctgatcggta cgaagcacaa aatactcata tatacgaaaa ataaagcata cacaatacac
     6421 ggccagcaca cagtataaaa cattaatttt ttcaagacgc atacgaaata ctccacaaaa
     6481 tatagtggtt ttagggcgca aaaaattacc gcaaaaataa tattttgttt tcagagatag
     6541 tggttttaag taaattttcg tcgaacaatg agcatattta tttcctgaac ctcccggcgc
     6601 atatgcaaaa tattcagggc ggttgaggcg ccatacatca cgattcccag aatgcacagg
     6661 atccagagcg gggtgctgga aaaccagccg aacgccagcc cgctgccgca gatcatgacg
     6721 aggataaggg ctatatcgac aagcgcctcc agcaggggat atttcagtgc catgcgcgaa
     6781 accagcagca tacccacatg aatcatcata ttggtcgcga gaacttggaa gactcccaca
     6841 aggtaaagat acgttccacc tgataacaga ccgatgacgg ccagtaaaat gagggagata
     6901 cccgtggtcg cacaaatatt aacagcaagt tttctcatgc accgtatcct ttcaacgctt
     6961 gtttgacgtt tttgaggtat gtgcgattta tatagacttt atcgccggtt gttaatatgg
     7021 cttccatgcg gctattaaaa agcggtttaa cactctcaag aacgttaatg ttgagaatgc
     7081 atgacttact cacccgcaca aatccacaat cttgaagttt ctccgcaagg tcgtagagcc
     7141 tatggtcggt cctatacgta tttcctgcta cgtgcacaaa cgttgttttc ttaacgcttt
     7201 cacaatagaa aatatctgaa gcgttcacca tgatgtcggt gcttccgttt tcgcatttaa
     7261 tccgctgctc caccgattcc acaaaatcga cgatgcggct gacccgcaca tccttctggg
     7321 cataaacgat actcacctcg ggttcctgat aggcaggatc ctcgcataat ctcagcttca
     7381 ccacatcacc tcatgcacag cctaacatgc ggcgaaccta tgcaggatgg gtatcgacta
     7441 agctgcatga agacacgacc aagctacaga aatacccccc cccatagagg ttgttcacca
     7501 cagtttagag agcatgtgcc gtcatgtttt acccgtcatg ccatggcagc tgtatcgtta
     7561 agtttcactg acatgccccg cagattcctg cacataccga tttcttcgcc ggaaggcagg
     7621 cttaccccag ccaccgggag ttatcggcgg ccttatgcat cctggccgca gtagcctccc
     7681 ggtacctgga gccgctgctc cagaatgagg tcctgcacct aaaccgcggg gcagattcaa
     7741 cccccaccca cgccatatgg tcatacaggc tttcttcgta ttcccgctgc tcgtcctggg
     7801 gttcctgggc ctgcggcttc ccttgagcct gcggtgcctc atgggcacgg atctcttgtg
     7861 cgatgctttc agggtcctcc aggtagtaca gatcccggta gcggccaggg acccggatca
     7921 gctcatcatg gcttccgctc tggataatgc gcccgccctc caaaacaata atccgctggg
     7981 cgttgcgaat agtggagaga cggtgcgcca ccacaacctt cgtgcactta taccgtgcaa
     8041 tcagctccgt cacctgacgc tcagtggtgg tatctaacgc gctcgttgcc tcatccagca
     8101 ccaggatgcg cgggcgccgc agcagcgccg tcacaatggc gatgcgctga cgctgcccgc
     8161 ctgagaagtt ctcaccatca ctggacatga tcgtgtcaaa ccccatgggc agacccttca
     8221 caaaatccag aatacccatg ctcagcacat ccgcttcgat ctcctcgcgg gttcggccat
     8281 catcaagccc cgccgtgaga ttctcgtaca gggtgccgcc ccttgtctgc agctgctgcg
     8341 gaacataccc aatgtgggag cgaagcgcat ccaaggaata atcctgcaca ttgatcccgc
     8401 ccatccgaat agtgccggac accgggctgt acagcgaaca tagcagcata gccagcgtgc
     8461 tcttgcccga cccggatgag cccacaaggg ctatgtcatg cccctctggc accgtaatag
     8521 acacctcaga aagcacgggc tgcgttccgc cggggtaagt aaagttcacg ttctcaagct
     8581 caatatcgct gctggcaagc ttagtgatgg tgccgccatc ctgctcaggg tcgtaacgct
     8641 gaatatcaac gatacgcgcc accgcccggt ccacggcaat aatgttcata atgccgaaca
     8701 tcgttgacga aatagaggag aacagcatgg cagaaatacc ctcggtggcg atagcctgcc
     8761 cgagcgtgag cacgccctga ttcaccagag gaagcgaagc cagcagcaga atcagcggcc
     8821 cgcccagctg caccacggaa gctgcggaac caagcacacc ctgctgcagc accatgcggc
     8881 ggcgcattga ggcaagcgac tgtttgtacg cctcacgcca cgtctcatat gtggagcttg
     8941 ccgaaccagt cattttcatg gatgccacgg tgttaatggc atcaagttcg accacctggg
     9001 cttctgaggc gtgcgcatat tcggcgtcga gcgcctggga ggtggggcgt gccgtcacga
     9061 accagatcag catcagcacg gcgagtacca cgaaggtgat aatgaggatt tcgcgtgact
     9121 gctgggcgat gaagacgaga atcacgatca tcgtaccgat attaatcacg agctcagtca
     9181 ggttcgtgga cagaaagttc cgcagcgtat tgacgctgga aagacggtac agaatatcgc
     9241 ccggggagcg gagcgcaaag taggtcagcg gcagcttcag cagccttttg aacatcccgc
     9301 ccagcagctg gtacccgatg gacgagacga tactagccaa agccgcggca cgggcgatgg
     9361 acaccaggta gtagcccgcc acgccaacaa ccacgccgat agttgcgacg aggatggcgt
     9421 cttcatggcc tctgagttgg gcgtccacca cgctttggat caccaccggc acggcgaacg
     9481 taacgctgta ggtaatcacc agcagcacca cgaaaaccgc gtactgggcg aacatctttt
     9541 tcgtgaagaa cgtgttcagc tgccagtctt ggaagacttt tcgggatttc tttttaaagt
     9601 ctttccgggg ggtgggaacc agcacgctac cggagaaaga gccttcagct tcctgaaggg
     9661 ggataacttt catccccgtt gcggggtcca taatatgtac gcggtcttta cggatgcgta
     9721 ccagcaccac atagtgggag ttgttccagt gcaggatagc tggcttgccg atatcgcgca
     9781 actgttccag cgagttagct ttgtacgccc cgacgtccat accttctgcc atgagaaggt
     9841 tgcgcacttg gagcatgctc aggccttcac gcccgggttc ggcaatgagg cgcagatcag
     9901 atatcgtctg ataccgcccg taatgctgca atacggacgc gccgacacct agcccgcact
     9961 cagtagcagc cgcttggaga accgctggaa accccatatt ttaccggtcc tcactcacgt
    10021 caggaatgac gggggtgtat aaacgccctc cccctaaacg gtgagccagc cacgacagca
    10081 ccccggaggt acccaccagc agtgacgggg tcagtgagta ccgtgaagac ttatcgtcaa
    10141 gtgtcgcgcg aataactgag gggccgtacc cgtttttgac ggctgcacgg atatcctcgg
    10201 cgtcgggcac atcgggaacg cgagcaataa tccagttgag cacctccagg gttcctaagt
    10261 ccccgtggca caacgtcaag ttactcctag ttccggtacg gaacgcgtac tgcaccgccc
    10321 ggtcgagctc agtacgcggg gagaactccg gcatccacac gtgtacggct gcgagtgcaa
    10381 gagcgatacc cgcagagcca gagcaccatg tgccgccggt gtgtgcgtcg ccagtgccgc
    10441 tgcgttcgga gagctgggcc cgccagcctt ccgcgcacct gaaactgttc agccgctgca
    10501 ggagaatctt cacggcatgt tgagcgcgcc caggtgtggg catctcctgt ccccagcggg
    10561 ccagagcaaa aattgacccg ctcacaccgt aggcgaaccc gctcacattc caccagttct
    10621 cctcaacccg gccagcaaca atatccaggg cgtgcttttc gagcacctcc agcagggcgg
    10681 cgcggttggt ggcgaggtta taccccagaa gtagtgtggc ggcgcctacc tggttatcca
    10741 ggtaccccgg catcggatgc tccacctgct ccatacgggc ggcaacccgg tcgccaagca
    10801 taatggcggc ttctttcagc cgggggtcgt ccaagtactc tgcggcgctg gcaagtgaga
    10861 gcgcgatacc cgcctcaccg cctgagacac cgtcgcaggt ctccggggga atgctaaaga
    10921 gcctcttatc gaagacatcc tgcgctatcg ggtctaacac acggtgcgca gcctgagcgt
    10981 actccgcgtt tcctagcgtg tgtgctgcct gggctagggc catcgcaggc ccgaccgacc
    11041 cggtgtacag gtctatccca agaaccgtgg tttgccatgc accaatatgc tgctgccaga
    11101 gcccggggtt aggtgcgagc cacgtccggg agtcttgctc actgcctcct aggcgcagag
    11161 tgcccgtcag ctggtctgcg atcgcggcgc aaagctcccg ttcgtgctgt tcgtcttccc
    11221 cggcggagag taattctgcc gggctattgg ccagggtgtt cgccgggtag ggtgagatga
    11281 aggcggccca gatctgttgg agctgctcct ctaggtcatt ctcgtcaagg gtggcaatat
    11341 gccgcagggt ttcttccagg gcgctgcctt taatgctgag ccccaccggt ttgccctcaa
    11401 acgatacgat gtcagagcca tccgtctggt gcatgaagaa gggtacgtcg aaccgccaga
    11461 gagcttccgc ttcagccgca accatatcca gggggcggtt gtggcttagg gtggcggcgc
    11521 gcagccctac cgtggcgaac acttcttggg atgcgagcgc ctcgggactg ctgagcatct
    11581 taaggatttg ggtgtaaaac ctggttgatt gcagcagggc gcgaagcatc agcccggtaa
    11641 agttcgcgcg aaccgcctca agcatcgcct cgcggtgctc acagatccat tggtgcatct
    11701 gcgtaaaccc tcgggcgaag gcacgggcac gggcagcttc atagagacgc cgctcttcca
    11761 gcacctcaac actagattcg tcgccgacga gtgccaccat gcttgccgct tcttggttct
    11821 cctctggggc tggggccggt tcgcggttca tccgggcggc agcatcgtcc cggaagggac
    11881 gctcaacaat gacctcatta aacgggtcat tcccctgctc cccgtggagg aagccgacgt
    11941 cacggtaccc cagggaggcg tcgcggcgcg taatacgggt gggcagaaac gcgctattgg
    12001 aaatcccacg gagttttcgc aggtgggcgc tgccttcagg cggttgaggg gtgtcatcgg
    12061 cgaggatgta tatggggtga agcaccgtct caaggtcaat cggcacgggc ccggtggcca
    12121 gggggatcag gttcttggcg tgcatatctt tgccctgcaa tgcgtagagc aaacccgcta
    12181 gccggccgga ggcttctaag aagtcttcgc ctgagaaatc tacctcctca gctttaataa
    12241 actccatgaa gccgtaaccc tcaccctgga ttacccgggc ggcacgcata gcgggtgccc
    12301 cctgctgagt aaggtcttga acgatctgcc agaatgctcg ctcgccctca acgttgcgtg
    12361 atttgtagac cactgtgccc tgcgtgaact taaggaggca gccagcacgc ccgccgccgt
    12421 aacgagttcg gggcagcccg aaagattcaa gctgaagtgg tgcggcatcc gtggtattca
    12481 aaagctcacg gatatcgttt tcgtgggtgc ggacacgctc gaaaatctcg gcgatcatcg
    12541 cgtgaaattg ctgcaccgtc acctggtgga tacggttcag aagtgggtag cttgcgtgga
    12601 agtcatcgct tagttcttcg tgccagcggc ggcagtagtc ttcgtagcgc ccttccggtg
    12661 tgtctgcctg caatagcccc tgcgcagagg cctttttgat gtgggcaacc agtggtctga
    12721 ggtagaaatt gtttaaacgc gccgttaggt tatccaagaa ttggttggtt aaacggtgga
    12781 tctgcgacgt tacagcgtag cccgatgagg tgatggcgtg ttcgacgttt ccacgttcat
    12841 tctccgccag ctgggcgatg agcgcgtgga acatggaggg ttcagcagtc ggccccagtg
    12901 ccgaagacac cggagccgac aaccgtacaa taaaatcgga gtcaggcgct tcggatgcgg
    12961 tggtgcctat ccgttctagt aacgaagtgc tagatacgta agatgctagg cgttggaatt
    13021 gttcctcatc cagttcagga agaagttccc tgattaacac ctgaattctc cttatctatc
    13081 gtatttactt atcctctgga tttaggagaa gctgccgccc cagaagccaa agccgtagcc
    13141 gtagccgccg cagccgccgc cgcagtagcc gccaccgtag ctgccgccac caacggagct
    13201 gtagtagccg ccaccgtggg agccgccacc gttaacctga ccgagttcct gatcggagat
    13261 ctcttccaga agcgtgatat ccttgggcat ggttatcctc cttatgtatt cctgaaccaa
    13321 tttcaggaat agtattatcg gtgtcagttt gatgttttac catcaaactc tagctgggtt
    13381 ccgcaatgac aacgttccaa ggcgccacgt tggaacccac ctccttttca tctgggtgtt
    13441 aggtaaccca atcaaaaagg aaacttgtaa agttttaatt ccccagtggg gttttaaggt
    13501 ataaactaac cagtcacctc tgacaacatt tcatcgctaa agaaatgtgc agcggaaata
    13561 ggtattctaa agatctgtaa atgtgttcgt cagtaaggca aagtccaatt tcagatcacg
    13621 ccacacactg cgtcgtacat gctgtctgca ctattttggc gcaacaacat ggccgccaca
    13681 cagtagagta gcgctacgtc atgtggaaac tttaggatgc ttgagagtgt aaaactttcc
    13741 ctatcaaatt taggggccca atatcagttt tcggaagctc tcaacgctac ctattctttg
    13801 catcttcaat agaatacccg caataaattt tcgtccctgt aataaatcta ttgcgtttct
    13861 ggttagctac tcaactataa caaatccccg gggtaggtgc aatagatttt ctgggaaaat
    13921 cagagtattc caccctcaat gagaggtgtt atccgttaca ccaaaataac cccgagcact
    13981 gcctattagt gagcctcggc cgagtcagga actatggggg tatataggtg ggtatcccct
    14041 gcccggcgag tcaaccacaa cagcaccccg gaggtgccca ccatcagaga aggcgtcaga
    14101 gagtaacgaa cagatttatc gttcagcgtc tcacgcagca gggaaacgtt ataaccgttc
    14161 ttgacggcat catggacagc ctctgcattg gacacatcgg gaacgtgcga gaccacccat
    14221 tcaaggacgt caagggttcc cagggcacca tgacaagagg tgaagttacg cttggttccc
    14281 tcctgcaggg aacgccggac tgcacggtca aggctcgcgc ggttagaaag ttcagggagc
    14341 caacagtgca cagccgctaa ggctaaggcg acacccgcgc taccgtggca ccaggtgccg
    14401 tcgtgggcgc tctccccaat aggtacccgc atctgccagt attccccgtt atcaagctca
    14461 tccaagcggt tcagcaaagt ggcgactgcc tgccgggcac gctctggtga gggcatgtct
    14521 tggctccacc ggctgagggc gaaaattgac gagctcatgc cggtggcaaa cccgctctgt
    14581 gcccaccacg catcatcaat acggccagca ataatgtcct gggcgtgccg gtctaacacg
    14641 gccagcggcg cctgacggtc agtggccagt tcatgcccca gcagaagagt tgccgcgccc
    14701 acatggccgc tcagatagcc gggggttggg tgctccacct tcgctatacg tgcagccact
    14761 tggttcccca gctcaagagc ggcatctttt agccgcgtgt caccaaggta gcgggcgcca
    14821 ccggcaagag tgaaagcgat accgggttca ccggcaaaag ccatgtcgcg tatatactca
    14881 ggcagcttaa gcgatttttc ccccgaaaga atagtctcag ctagcgggtc gaatacgcgg
    14941 tgagcagtct cagcatattc ttggtgcccc agcacgtgtg ctgcttgcgc taacgccaac
    15001 gcaataccca ctgagccgcc gtagagatcc gtctgcaaaa catcagtatt ccaaatacca
    15061 tgatggtgct gctgactgct cgggacaggg ctaacccacg tccacggatc ctccggggcg
    15121 gtgcctgaat gaaccgtagc cgccagccgg tcggcgatcg cggtgctgag ttcacgctct
    15181 tcccgctctc ccccacggcc ctgtcggatg tctgccggtt catccgctag agtattcgcg
    15241 gggtacgggg agataaaagc agaccagatc tggttcagct gctcgtcaag gtcgtcttca
    15301 tccatgtggg aaatgtggtt aagagtctcc tcaagagcgc tggttttaat gcccaagccc
    15361 acctcttgcc cgtcgggtgt catgatcgcg gtacgatcgg cccgatgttt aaagaacggg
    15421 atatcgagct gccacagtga ctctacttct gctaagacca gttccaggga acgatcgtcg
    15481 tcaaaggctg cggtacgtag cgccactgtc gcaaaaacac ttttagagga taatgcctcg
    15541 gggctgccga gcatccgtac cagctgctcg tattgcatgg tgggctgcag cacggcccga
    15601 agagtcagcg cagcacattc gctgcgtacc agctcctgca tagcgtcacg gtgctcacac
    15661 acccaccggt acatttgctc aaacccgcgc acaaacccgc gggcacgggc aacttccgtg
    15721 gcgcgccgtt tctcaagggt gtgggtatcc ggatcggtgc cctgttgggg gccgccgagg
    15781 tcagagtacc ggacagaccg gacaatagcg tcatcccgga aaggttgctc aatgaccgta
    15841 cctttgaagg ggtttgcccc ctgctcaccc cggataaagc caatatcaac ataccctttt
    15901 gaggggtctt tacgtaccag ccgggtgggc agtaaagcgc tggtacaaat accgcgttct
    15961 ttatgtaaca aagcgctgtt gtcgggtatg tctgctttac catcgttcag aaggtgtgag
    16021 cagtgcagta ttgtttcgag gtcaataggg acagcgccct cgctcgttgg gatgaggttc
    16081 tcctcgtgca tgtctttgcc cagcagagcg tagaaaagag ctgacagctg ccccgaagac
    16141 tctaagaatt tttcggccgt gaagtctacg tcttctctct caataaactc catgaacccg
    16201 tagtcttcac cctgaacgac ccgggcggca cgcatgcggg gggcgccctg ttccgcaagt
    16261 ttctgaacga tcctgtagaa cgcccgttcg ccatcaacgc tacgtggttt ataagccacc
    16321 gtcccctggc taaacaccag caggcagccg gtgcgtccac cgttatggta gtcacccgcc
    16381 atggtgaggg actcaagggt gaggggctca gcattttgcg cccctaaaag ctcacgaatg
    16441 ccgctttctt gggcctggat tcgctcaaaa agctccgccg ctatagcgtg gaattggtgc
    16501 acaataatgc tgtggacccg ccgcagaaga ggatagttcg tatagaaacc atccatgaaa
    16561 tctttaggcc agcggcggca gtagtctatg taccgctctt ccggggtgtc cccttgcagc
    16621 agcccttcag aggaaacttt cttaatatgg gcgaccagcg gccgaatata gaaattcgcc
    16681 aggcgcaccg tgaactcatc aaggagccca ccaacaatgt ttgggaagtg ttctttatca
    16741 acatagtgtg aggcacgaac agcctgtact acgcgcttat attcactctc aaaaagccac
    16801 gcaaaaagcg tgtaaaacat agcaggttcg gccgtcggcc ccagtgctga aggcactgga
    16861 gctgacggcc gcccaacagg tggggaatct gaggtggtgt ctaaccggtc gagtaaagaa
    16921 acgtctgaca catctgacac cagttgctgg aactgttcat catccagctc aggaagaagt
    16981 tccctgatta gcactcagta ttccccttgt ctatgttttg ttattagcag gagtagccgt
    17041 acccaacagc agcgtagtag tagccgccac cgtagtagct gctgccgctg ccgcagtagc
    17101 tgccaccgta gctaccgcca tagctgccac cgtagtatcc acagctgctg taacagccgc
    17161 cgttaacctg ctccagctcc tggtcggtca gttcttccat gaacatggta tccttagcca
    17221 tggttatcct ccttatgaat tcctgaatag cctcaggaat gattgtggtt aatcaatagt
    17281 ttgatgtttt ccatcaaact ttggctgggt tccaagatga caacgttcca aaggtgacag
    17341 cttggaaccc acctccttta ttgcaggggt gcacccccct caaaaggaaa cttatagagt
    17401 ttttaatgac cattttgggt ggtcgagaat agagacctag ccagcagttc cccaaaatat
    17461 tccgctatta aaaattgcag cagaaaataa ttgccgctta atctttaaaa gacttgaaga
    17521 atgagttcgc tagaaaaagt taagctctct atatttgtca gcaaagtata tttcctctac
    17581 gatgatgcct atcacctagc taccacgcca caatacactt gctctgtgca ttaatagcgc
    17641 tatactacgg ccaccacatc acaaagtggt gcgacatcaa atggaaactt aggatatgtg
    17701 agagtgtaaa actgttccta tcacacaata ggagcccaat atcagctttc ggaagctctc
    17761 gatgctatcc attctttgca tcctcaatag aacacccaca ataagttctc gtccctgtaa
    17821 taaacttatt gcgactctgg ctagcccctc aactgtatca aaccaccggg gaagtatgca
    17881 ataggtcctc atcataattt ccaaaacttt tctcagagcc gaagcaggtt cgcggggtaa
    17941 tcattatttc cgcggtaaat ccccctattt acccggtggt gcccgccaaa aaccgacagc
    18001 agctttcaag aactgcacag ctcgctcagg atgcgctggg ctgcttttcg ggcgctctcg
    18061 ccagcggcgc cagcctcata ggcgtgcagc gcatctgccg ccacatgcag gcgcagcacc
    18121 cgcggaaggg cagaaacctc acgcagaatc acattcgccc gcgtgggtgg agcaggttcc
    18181 aaaccccaac tcggggcaaa ttttgtgagg tcaccggaca gaatataggc gtctattaga
    18241 ggggttttta tccttgaaag ctcgtgccga accccggtga gcgcgagcgc atccgcaccc
    18301 gttcgcagca agtcgctcgt atcgtagggt gccacatagt agtgcacggt catcccggtg
    18361 cggcgcgtgt actgtcggag tgtatcaagc ccgcaagcgc agaggatgcg ggcgcgttcg
    18421 gcggcaatgc ggcgcgcatc cggggtaagc aggtgccctc ccccgttgaa atagagggcg
    18481 agctcgtcga aagattcctg cgagataacg tcactcatgg cataaacata gcaaacacag
    18541 aataatccgt ggttgcttta cctctcacga tcgacatata tggcaaaaat aatcctattt
    18601 cggtattatt ttgccatgca gtcggtatca gattacgcaa aacatgctgg ggttagttct
    18661 cgtagcgttc gggcgcgcct tgaacgtggg tctttgagcg gagaaaaatt tgctggtcgc
    18721 tggatggtgt tggatagtcc tcggaaccat cgttctttga gcggacgcaa gatttctatg
    18781 aactctttca accaacttgc ggcttatatc gacgatcgta cgatcgctat ttctccagat
    18841 gctcgacgtc gcgctaaaga gcgagcgcag gtcctcgccc atactggtct taaagcttta
    18901 gagcggtacc aagaacgtag cgggatgaaa gttcattact tccgtgcaga tcctagcaat
    18961 cttgagaaat tacgccatga atctgcgctg caaatgacgg gggtaagcca cgacatttcg
    19021 gaggtttatt catcttttac tgatgcctat gttaagacgt gggatcttga aactgtggtc
    19081 tacaaataca ggttagagcc gcgtttatcg gtacgagaag cgaacgtgct actccgtgaa
    19141 gttgaagaat tgcctcatat ttatagcctt cacatcgcgt tagatctcct ggatttacgc
    19201 gatgcacgca gtcggtccga ggctgaacgg cttctaggga aggttctgca tgagccgcat
    19261 cattagaatt gatgccagcg gaccggagct tgagtcatgg ctgggtcttg caacatgtat
    19321 aaaataagta cattgattta taatcaactt ttaaaagtat agtttacgaa gataataata
    19381 ccaagctgca tttccattag aacagattac tggcgtaaat tttgtaactc ataccgctat
    19441 aacagcatat ataaaaagct tttttcacat ataagttaag gatagtaagc taccttcgta
    19501 aataatcctc aaagctcaca tcaacttaga ggatatttag ccgcttccaa ggattcactt
    19561 acaagagacc aatgtataaa gcggctcccg cgatccgaat atttaaacca actatttttc
    19621 tcaccgaaag aagctaattc atgaatatct tccgcaacaa gaagtggact cccattgtct
    19681 tgttcctcat atatactgcc attataatca aatcgccatc cccgattctc agcaacttgt
    19741 gctgctaaaa agtgcgggtg aagatctaaa ccagtatttg ttccaggaac actaaattct
    19801 gtcaatccct cccacgtaat tttactgtta ggttgcttct taccaaacca agacataaaa
    19861 accctttcac agaaattttc aaatagaatg atacgcatac tacagtatca cagatttata
    19921 tagtttatgt agaaaattta cctacccgac ctcgccgtct aggtagtacc aggtgccgtt
    19981 gactttctcg aagcgggact tttcctgcat ggtgcctttc acatgttctt tggcgggcgt
    20041 gccgggaacc gagcggtagt acgccgcaaa ctcgaccgtg cccgccgcat cgaagggacc
    20101 gcccgaagag cccagaatat ccagccggta ccagcgcagc gtttcatcca gcgttaactc
    20161 tgcggggcgc gtatgcgggt gccagctcgc cagcaggtag ggagcatcgt gcagggcgaa
    20221 agcggtaaac cgcgagcgca tcagggccag cggtgtgggc gcgttcaggg ttccggatgc
    20281 ggcaaactcg cccaggtacc gcccgcagca ggcaccgtat atctcgccgc ttgtgcagga
    20341 gcagcgggtt tgaggatcat acaggattgt ttcgctcatg caccccattc taaacgtgcg
    20401 tgaaaaagag cctttattcg aataaagcgg catttttaat gctttattca aataaaggct
    20461 ctttttattg ccctaggagg ggacattttg caaccatgcg cacaggcgca gcgggtttag
    20521 tttgcgatag cgcgtgccgg ggtatctgcc gtggagggct tacccacgta ggcgccacgg
    20581 tacttcgcgg ccgggtggga gtctgcaacc ttagtctgtc ccttaccgaa caggctttcg
    20641 cgcagggtct caccttcgta ggaggtgcgg tagcgtccac gcttttgcag ctcaggaacc
    20701 acgaactcga tgaagtcctc gaaggagccg ggcgaaacgt ggtatgccag gttaataccg
    20761 tccagtccgc cttcatcaat ccagcgttcg agttcgtcag ccacctgctg cgggtcgccc
    20821 acaataacct cgcccatacc gccaatagtg cagtgctcgg caatatcctt acgcgtccac
    20881 tgcttatcct tggcctgcag ggtgaagggg gtgaggaagg actgaatcga ctcggtcttc
    20941 acatagttga gaacctcgtc ctcgtcgaac tgggaaagat ccacgccaga ccagccgccg
    21001 ataatggcct gcgaagattc caggttcacg tacttgcggt actcttcgta ctttgccttc
    21061 gccttctctt cggtctcgtc cacaataatg gagagcatcg cgaaaacctt gatttcgtcg
    21121 cggccgcggc cgttctcttc tgcgcggtca cgaatgcggt cggtaataat gcgggtcaga
    21181 tcggggcgca gcgcaccgat aaacacaacc tcggcatgct tgcccgagaa cttctgcccg
    21241 cggctggatg cgcccgcctg gaaaatcacc ggggtgcgct gggggctggg ctcggtcagc
    21301 cccgcgccag gcacgctgaa gtacttgccc ttgtgctgaa tcgggtgcac cttagcaggg
    21361 tcggcgtaga tgcccttctc gcgatccttg acgaccgcgc cgtcttccca ggagccttcc
    21421 cagagcttgt aacagacgtc caggaactct tcggcgagtt cgtatcgggt gtcgtgctca
    21481 atctgggttt cgaggccctg acattcggcg gcggaaggca ggtatgaggt caccacgtta
    21541 aagcccacac gcccgttagt gaggtggtca agagaagcgt acttgcgggc aagcgtgtaa
    21601 ggctgctcgt aggtgacagc tgaggtcacg ccaaagccca ggtgctcggt cacggcggcc
    21661 attgcggaga tctgcataaa cggatcgttc acgggcacct gagcgccgcc ttcgatagca
    21721 ggtgcggcgg agttcttgta aatatcgtag atgcccacaa catcggctaa gaatacgccg
    21781 tcaaagaagc ccttctcaag gatctgtgcc aggtcagtcc agtatttgat ggtgttgtac
    21841 tcggtagcgc gggagcgggg gtggcgccag aggtcaaagc tttggtgacc cacacaggtc
    21901 atgtcgaatg cgttaactgc gatgcgcttc ttctgctcag ccatctacgt tcctttcgcg
    21961 aatgttcggg tgttcctgca ccccgcgcgc cgcctcctta taggtggtgg ccttcttggt
    22021 gttccaagtt gtgcaggtgg cgcattcgcg ccgtacttgc ttcgtgttcc ttgaagccag
    22081 atcatcatct ggggcacccc gctacgggag agggttgccg cccggctagc cagagcttta
    22141 cgccgggact cataatcctt gcgttctgag tgtatcccct cgcagatggg gtgaacagta
    22201 tatgacgaac attaattttt gtgactccgc accgtaatat ttcgcatgaa tcatgcaata
    22261 tttagtcacc gttagtcacg gtacgtcatg tgttttcgct gcaatggcgc cctcctctag
    22321 ggttataggc gtaacccatc cagagcgact gagagacctg gctcgacgac gtcgcagcaa
    22381 cccctagcgg gtgctaacgc caggaccgat ggaagtaaca tgacacagaa tcaccacacc
    22441 cagctacccg ccaacgccca gacgatcact ttcgacgccg tcagccagtc gttcccacag
    22501 tccggcaaga acacgcacga ggtgcttcgc gaagtaagtt ttaccgccgc cgcgggagaa
    22561 attatttcgg tcattggcgc atcaggatgc ggcaagtcaa cgttgttgcg ggccgccgcc
    22621 ggactgaacc gcattacggg cgggcaggtg cgcatcgaca acaccccggt gagcgggctt
    22681 gatcagcggg tggcaatcgg ttttcaggag ccgcgcctgc tgccctggcg caccgtcgcc
    22741 gataatgtag cgcttgggct gccgcagggc accccaaaga cacgagcgca ggagcgcatc
    22801 cgcgagctgc tgcgcctggt ggggctcgcc gactacgcca cgcaccgtcc caaagaaatc
    22861 tccggcggaa tggctcagag ggtttctttg gcgagggcgc tggcgcgtga acccggggtg
    22921 ctgctgctgg acgaaccgtt tggggcgctt gatgcgctga cccgcattaa aatgcaggat
    22981 ctgctgctgg atattcacag acaggaccca accacggttc tgctggtcac ccacgatgtg
    23041 gaagaggcgc tgtacctctc agaccgggtg attgtgcttg gtaagcccgc gcccgatgcg
    23101 tccgcaacga tcacacgtgt agtcaccatt agcgacgccc acccgcgtga tagggccagc
    23161 aaagagctaa ctgccctgcg ggctgagctg ctgacagagc tcggcgtgga aaaagccgat
    23221 accgccttgg ttcccgccta gaacagggcg ctgactcccg cgtgctctag ggccgccgca
    23281 cgccttcacc ccctcttggt gaataattat tcatcttctt actgtttttc tcaccccatc
    23341 agatacccaa ggattaccca tgacagccat caccagagct gaagctctta agggcttgct
    23401 ggccttcagc gccctcacca ccgttcttgc cggatgcgcc ggagaaggcg caggaaaccc
    23461 cggcgcggga tccgcaaaag gcaaagacac tgtgaccgtg gattacgcca cctacaaccc
    23521 gctctccctt gttattaaaa agaaagggtg gttagagaag gcccttcagg aaaaaggtaa
    23581 aaaactggaa tgggtcaaat cagccgggtc aaacaaagcc aatgaggctc tgcgttcggg
    23641 aaacattgat gtgggctcaa ctgccggttc tgccgcgctg ctggcccgcg cgaacggctc
    23701 acccattaag gtgattgacc tgtactcgca gcccgaatgg tcggcgctgg tcaccaccaa
    23761 aaactcgaat attcatgcag tatcagattt aaagggtaag tcggtggcgg tcaccaaagg
    23821 aaccgacccg tacttcctgc tgctccaagc gctcaagcag gaaggcatcg cggcaaaaga
    23881 ggtaaccatc cagaacctgc agcacgccga tgggcggacc gccctcgata acgggcaggt
    23941 caacgcctgg agcgggctcg acccgattat ggccagcgcg gaaatcgaaa gccacgacgt
    24001 actgttctac cgcaacctag acttcaatac gtacgggttc ctcaacgcca ccgagcagtt
    24061 cctcacagac aacccggacg cggcgcaaac catcgtgaac gtgtatgagt atgcacgcaa
    24121 atgggcgctg gaaaacactg ctgaagcaac ccagattctc gccgacgagt ccggtattaa
    24181 gttagaaacc gccaaactcg tgatggaacg aacccacctg aatattgacc caatcccagg
    24241 ggacaagcag gtgcaggtgc tcaaaggtgt tggcccgatc ctcgtcgaat ccggggacgt
    24301 ccccaaccag tcagacattg ataaggcgct gagcagcatc gtggacgaca catacgccaa
    24361 gaaagccgac agcgccgccg ttgagaacgt gaagaagacg gtgagctagc catgagtgta
    24421 accctcgaca aaatttccaa cgccccggaa ctttcagata cccccaaaca cacgaaatcc
    24481 gcagccgcag aaaccgccgc agcccgcacg gcagctgcca gcaccgctgc cgggcgcacc
    24541 caattggcga gctcccaccg cggccagccc cggccaaggc gcgccctgcc cctgggtgct
    24601 aaacactatg tggggcttat cctgcctgca gcgctcatca tgctgtggta tgtgctgagc
    24661 accgccgggg tattcaccgc ggtgcagctg cccgccccca cccgcgtcat agccgccgga
    24721 accgagctgg cccagcgcgg tgagctagca acccacctgg taatctccac ccagcgggtg
    24781 gtgctcgggt tcagcatcgg cgcggtgctg gggctgtttc tgggggcgat tatcgggctg
    24841 tgggggcccg cgcgcatcgc cgcagcgccc accattgggg cgttacgcgc cgtgccctcg
    24901 ctcgcctggg ttccgttgct gctgctgtgg atcggcatcg gcgagaactc taaagtaacg
    24961 cttgtggcaa tcggcgcgtt cttccccgtg tacaccaccg tctcggcggc actggcacac
    25021 gtggatccta aacttgtaga ggctgcacgc gccttcgggt accggggcgt taagcttttc
    25081 actaccgtcc agctgcccgc cgtgctgccg tctgtggtgt cgggtctgcg cctggcgtta
    25141 gcgcaggcct ggctgttcct ggtggctgcc gagctattgg gggcctccat gggcttgggg
    25201 tacctgctca cagattcgca gaacaacggg cgcaccgacc gtctgctgct ggcaattgtg
    25261 ctgctggcgg tgctgggtaa gctcacagat gcgctcattg gcgtgtttga gcgctgggtg
    25321 aaggcaaaat accccagcaa ctaggcgcct tagccgtgcg gcgccccgaa aggaaacctt
    25381 ggtgaagtac agaccaagat attccttccg gggcgccact cagctgccta tcctctacag
    25441 cagttagggc agcaggccac gttcccgcgc gaattcagcg gttacctcgt tatagtccac
    25501 ctcaacctca tcggggtccg tccgcggggt actcgtcaca ccctgggacg tcgcgctggc
    25561 cgcaaaccgt agagtcttca tatcgctctt cgcccgcagc gtgctcatgc gccggttacc
    25621 gttcacatca gcggcgaccg gctgcgcatc aatcacgccg ttcttgttaa aatccacgtt
    25681 acggtgcgca ggtttgccct tacacaagta cccgtaggcg ttcgccccaa gcccgcgccg
    25741 ctcatccagg ttcttctcat ccagcggcat atgctcgtgc gttgaatacc cgaagtagtt
    25801 cttacccccg gcgcgcggca cgccgctgag ctggtactcg tagttcataa tgctcagata
    25861 gttcggcttg tagttctcct catcggcccc accgtgccgc agccccaagt tatgccccag
    25921 ctcgtggatg aatgtgccca ccctaatatc gctgctggca ccccgccagt aggtgtgccc
    25981 aacggtcaca ataaatccgc gagcgcccgt gaaacccagc cccgaagagc tcgtattgcc
    26041 gtaatagtcg ccccagatca tgtagtgaaa accagcgtca cgggccgagg cgaaatgacg
    26101 gtttttcagt gccgcccagt cccccatacc gttaagcttc tgatgcggaa tctcgttccc
    26161 gccgcccagg ttgtacttcg cgctgcgggc gggcccggca tccaggtgga tactcacacc
    26221 ccgcgtaccg tcagggttac gtagcggcag ggaggcgaac acctcggtaa tgcggtcaag
    26281 gtcggcttcg gtggcgagct caccgggcat gtagtccatc tcaacaaaaa tatctttacg
    26341 gtacgggttg gcccccatac ccgggtagtc aacgtcaact gtgccgtcgc catcggcgtc
    26401 atagccgctg atctcccatg cgttcgggat accgtcaccg tccgtatcat acgtgttgat
    26461 ggtgcttgcg ctggcgggga cggcaccggc tgcgattaaa actacggtcg cggcaaaaag
    26521 gcgcgcagat ttcatgaatg ccactgtggc tcctaggatg cttgtgaatt gagtgaatga
    26581 aatacagcta attggcgcac cacaaccacc cccgacacgc ggtacgcgcg gcgcgctgcg
    26641 acgcgcacca gcacgaaaat gcataaaaat ccgctatgtc cggggttgaa gtgcacaaat
    26701 tttcaaatat ttcctacaca taatagcgcc attacagcgc gcaggcacac ttgtctacta
    26761 cactggatag gtcgtattca ctcacatcgc atacattcac actctctcaa atacatacag
    26821 gagtccacgt gacccacgta cccttcaggg gcggcctcac gcggcgccgc gcactcgctg
    26881 gcgccgcatg gtccgccccc gccgtcgccg catccgcaac ggccccagcc tacgcagcct
    26941 cggaccaagt agttgccgtc gactacgggg tattcactca ggcgtttaac accaccatgg
    27001 ataaccccaa cagcaccttc ttcgggctcg actcgtacca cgggcagctc accgacacgc
    27061 gcgcatcccg caccaccaag tgggagggcc tgctcgccgc aggcgggggc acgttcaccc
    27121 ccggcggcag cgtcggcaac ggcctctacg ggggtgccgg gctatggttc gccgccccgc
    27181 acacagcatc cggcgaatac acgggaacca ccaccctgcg caccggggca cgtttcagca
    27241 tcaagtacac gttcacgttc gccgacgaga tacagacccg cccgcccctg ctgtgggagg
    27301 acggggaaca gcagcaggtg gctgcgctcg ctcaaagcgc cggtggtgcc cgctcgaaca
    27361 acccgcggct tgcggcgttc aacggggccg gtttcaccgc ggtattccgg gaatcagaca
    27421 gctacgggac ggagtggcgc ggcaccctcg acattgtcac cgctgaggac gcggtggcct
    27481 cagctgaggg gatgcaggtg tttaaccagg tgctgttgag ccaggtgccc gtgtactacg
    27541 accaggtggg tgagtcgttt agcctgcgaa caaccgtgac cgtggtggat gcgaccctgc
    27601 tgctggagcc ggtgaacagt gcggccccgt ccgagcagaa tattgcgggg ctttccgcca
    27661 gtgccactat cacccactcc cccgcgtagg ccctgcgcac gccgctaatg gatgagctga
    27721 ttagagacaa gctcccggta gaggggtgag aactccatga gtatgtcgtg cgtgccttgg
    27781 gcgacgatcc tgccgtgatc catcacgtaa atcatgtccg cattaacgac ggtggacatg
    27841 cggtgggcaa ccataatcat ggttgattcg ggggcggcgt tattgttcag cacagacacc
    27901 accagctctt cgctaatgcc gtcaagctgg gaggtgaact cgtccagcag gtacacctgc
    27961 gggtttttca ggatcacgcg ggctatggcc agccgctgct tctcaccccc ggataaggac
    28021 gtgccgctgc cgccaatgtt caggtccacg ccgtgccctg aacgttctag cactttttcc
    28081 agccccaaat ctttgaggat gcggtgcgcg gcagcgctat cggtgccgcg ccccgagatg
    28141 tagacgttat cgaggagcgt gcccagaatc aggggggatt cctgctgcac caggccgatt
    28201 ttggcgcgca cagccgggat ggaaatgtct gagcttgcgg tgccggagta gaggaggttc
    28261 ccgcctgaga tttcgtaaag ccgggcgatg agccgcagca gggtgctctt gcccgaaccg
    28321 gagggtccca cgatggcgat cttctccccc ggggcgatgc tgagcgtcat cccggaaatc
    28381 aggtagggtg aggccccttc ctcaggttcg gcaccgtatt taaagctgac gttatccagc
    28441 aggatggagc ggatatcacg gttttcgtgg tatgtgtcca gctgttcggg gtactcgtcc
    28501 gggatgccca ggatctcctg gatgcgggta atgcctccgc tggcttcggc aatattgctc
    28561 atggtgccga aaatgtaccc cagcggcatg atcatcataa ccaggaacat gacgaacgag
    28621 accaggttgc cgacggtaat tatcccgttc gcgaccctga ccccgccaac gccaagaacc
    28681 actaggaacg tgatctgcat ggccaccgca gagatggggg tgatgagggc gacaagccgt
    28741 gccactccga tccccttaag ccacgcatta tcgactttct gctgcagccg cttaaactgg
    28801 tgccccgccg cgttctccgt ccgaacgagt gaggaggcct ccaacacgct ggacacatcc
    28861 gagctcagct cacccaccgc ctgctgcatt tgcgcgctgg atttttcgac cttagaggtt
    28921 gccatcgtga cggacacgac cgccagcagg gatatgacgg cggaaatagc gagcagcagg
    28981 gggtcgatga agaacatccc gatcaccgcc ccaatgagcg tgaaaacacc cacgaacgac
    29041 tgcacgaacc cttccgtgag gcagcggcgc agcagcatcg tgtcattaat gacgcgggaa
    29101 aggacgtctc ctttggtgta tttctctaag gcgtccaggg ggatgcggag tattttccgc
    29161 acaagctgcg tgcgtgcgtc acgggccacc gattcggcga ctttctggat aaagtactgc
    29221 tgaacaccgt tgaggatggc cccgataatg agcaccagaa taatgagaac cggcaggtaa
    29281 ccaataccct gggcggatcc tgcggaatca acaagatcgt tcactattaa cggctgcaaa
    29341 agcgacgcgg ctgagcttgt gagactcatt aaacagataa cggtcagcag ccctttaaag
    29401 ggggatagat acgaaaaaac taccccccag gatgacttcc cattattttt agctttcacc
    29461 atagtctcat gcgcctcact tcttgggtgc cgccgccctc accctgtttt tgcctgaatg
    29521 gttacggcgt tagcgggctt ctgggttggt ggatgcgaca gtcacgaacc cctgcacatc
    29581 gtggtgctca ttaatgggtt ccccctcgac ggtgacccat gcgtgcgcaa ggaacggttt
    29641 cacccggaac ccggaagccc acaccacttt ccggcgcatg agagaaagca aaaggtaggt
    29701 tgagatggac cgtgccaggc acccccgctc cccacggcac agcggggaaa cttcacgcac
    29761 tttcgcatca accgcgagcg cctgctgaat ggatgagctt ttctgcaggg gccggaacat
    29821 tttcagcagg cgaacaataa cggtgaccgg caggcgcgca ataatctttg ccgcacacac
    29881 cgccaggcgc gctttgatac tgctgacggt gtgcgcgtct gttgcggtgg tggggttatc
    29941 acccatggtc ctcgcctttc tctaggacac ccatcgtcca cagttcccgc agggtgcctt
    30001 caaggtcctc ccgaatctcg tccgggtcgg attgtgtgta ctggcgaatg aaagagtcaa
    30061 tgatttctga gttgcggcgc ccctgctcca cgaggtccaa gatgtgctct gtggtgctgt
    30121 ttccttgaaa ataggcgctt cgggtgggca caaaaaccac gatgccggac tcggtgcccg
    30181 aaattttgac gccatcggcg atgcagaacc tctcgggcag tgacgcgtag cgtttataca
    30241 tagttttcac gtagccatac ctccatgtgg gtcatacgtt caaaatcgta gagtgtctct
    30301 gagctgccca gggggctgtt tgcgatcgtg cggacagtgt ctatatccac aaggttcagc
    30361 tccgccagga gactgtcgcc gatcattttc aggaagtttt ctttgctgcg ttcgtagtct
    30421 tggtacaggt cgaagctgta gtcgcttttg tagatgtccc ggtagaagaa ctcgggcagg
    30481 gtgcctttca tggcttccag gatgacgggt ttgctcatcc cgtgcccgct cagaacaccc
    30541 gggtacacca gggaggagcg gatcatgtcg tcctcaaggt agggtgcggc aaattccagg
    30601 ccggtttcgc tgaaatactc gttcatgccc cgaagcactt ccccctgaaa ttccagggac
    30661 ccgtagatgt ggaaccggta tttatccagt tcttcttcct ccggcgggat gggggtcgcc
    30721 ctcatgagct caatgacttg ctcggtagct tcttcggata gccaggaggg cagcgtaaag
    30781 ttcgggaacc aggagaaagc atcgatgttt tcagggatgt tctggccccg gcgggtcagg
    30841 cgccgctgca gctcacgctg tttcgtttct ggggagaaag cggcacgtaa tgtcgatact
    30901 ttcggccagc gggcggcggc cgcaacggag ctaatggctt taatagcccg cattttctca
    30961 ccctgtttga agtagagcag cgcctgaaca ggcatgggct caaacagctc gtccccgcca
    31021 attcccaggc agtggatgct ggagccgcgt tcccgcgcgc tgcgcacaag ggcggtaagg
    31081 tgcggaaggt tagcgtgcca tgcgcggggc gcctcggaaa acccgcgaag ctcgtccggg
    31141 atggtgaaac ctgcggtgct tttcgtaaat gagtcaagct taatgaggtc tatggcgaag
    31201 tgttcggcta ttttctgggc gagctgcgta tcgcggttgt ctttatcgtc cgtcccggcg
    31261 tgaaacgcgg tgaagggaac attctgcgct gcgaggagca cggatatgac cgtggagtcc
    31321 acgccgccgg acaggtcggc agatacgtgg gtgcgccctt cagccagccg cctcagaacc
    31381 gagttcaaaa cggtgtatac gtgctgtgac acatcggaaa aagatagggt gctgtcctgc
    31441 aggctgaggg catctgcgaa gtacgaggtg ttctgcacag acccgtgctc gtcttcgcat
    31501 acggtggtgg ctgggggcag cgccataatg ttctcccagt aggagacgcg gcgcacccac
    31561 cccggcgggt tacggcatag cccgagggcc acccgagaca tattaatagc gggattaagg
    31621 gcatccacta ggggttttac tgatgtgctc agaagatcca ccggccccag ctttgaacgg
    31681 tacacgctgc ggtgccgcga gacggaagat accagctcgc tacctgcggt ggagtcggtg
    31741 tttgatgcgg aagcctcatg agtgggtaac gggcgaacag ttatattatt cgagctgcta
    31801 cgaagaaagt gagaaatctt ctgcacgtta ccggatgttg tgtatagctc tgccacagga
    31861 ttccttatcg tcactttcca cattaaaaat atgggctcgt ttaattattg tttttaccgc
    31921 atcccacttt tatgcggatt tctgcgaata ataaacaagt cacctggcgc gcagggcgct
    31981 atttatagag caacttcagg gggagtcaca agccgggcac cggagagaac atcccggtat
    32041 ttcccgtata taaggccgtg agtgcaatct gcaaaagagt tcatcttcat aaaacgtgcc
    32101 ttaatataca tattcttccc cttttcttaa atattttaaa attctcaaat tacatatatt
    32161 atctacacag atttacccta acccgtaaat tgcatggttt gcaagggatt ctcacgatta
    32221 ttttaatttt tcctgaaagt atttctgctt aaaatagcag gtttacacga actgcccacc
    32281 accagcagcg ccggtaattc ccgcatatga gcagaagcaa ttaatgtcat agcagatacc
    32341 cgatgcgtga aaaggtgggc tgtgaatggc acgggctctg caaacattgg ttggcaactc
    32401 aatagaaaag tgggtgcctc agaagaggca cccactttaa gccttggcgg gaagctacca
    32461 tgagcctcca ctgacgcctc cgccggtgaa gccaccgccg ccttcgaacc cagagttagg
    32521 tccacggagc gcaccgaaaa tatctcgata gcttccccag aaccagccgt gagtagcttc
    32581 ctcgaaggag ccaagcctag taagttgcgc tttggtgtac atagaatttc acctcaacct
    32641 atcctctatt accactcgct tgagcctccg gcaccgttga aattagtcct ggggccatgc
    32701 cataccccgt aaacatcacg gtaacttccc cagagccagc cacgggtaat atgcgcaaaa
    32761 gaggaaatct ttttaaattc tggcttaata tacattatgc ccctcaaaca atatgtggaa
    32821 tatattgcat tacacaactg tgcatgaatt tccagaagtt tctaaataaa atgtatgtta
    32881 ttccggttct acccaaaggc aaagatgcta cttattagcg taccggaggg ctccgtaaat
    32941 atcacgacga ttcccccagt accatccatg agtagcggcc tggaaagagg taattttagt
    33001 gaacgttgct ttggtgtaca ttgcattatc caatcatcat aagcccaaat ttcttggaca
    33061 taggctcttc tagcctactg tggtgtagcg tagcttaaat tccctgcacc acacaagagt
    33121 ttttacatta ttttatagtt caaaaaacaa ttatttaccc gcaaatttta taggctgcaa
    33181 atatttatct ctgtaggata atgcctgccc ctgcgcttcc agcagctctt atagcagtct
    33241 aataacccat cttctggtga tagttttgat gatatccgct acatatgctg caaaatattc
    33301 accaggttcc ccagcggatc gcgaacaaaa aacctccgca cgccccaggg ctcttcagca
    33361 acaccgtatt caagcgtaat acctgccgta tgaatgcggg cgaggatttc atcaagatta
    33421 tctacttcaa ccgataaatc aggcaccggg gtacctgatc cgccttcact agctatgctg
    33481 acctgcacag tcgtagtttc cgcattgccg taagtctgta tccatccgtg atccatgagc
    33541 agctccaggc ccaggatgtc ccggtaaaaa gcagcagctg actcaggttt atcagcggca
    33601 agattagtaa cgatacgctt aacagccatc agacgcccct tccgtgagtg ttttattttg
    33661 gctcaatctt caggcactta cgatgaagcc tatcaagaga tgcaagccta cggggcaaga
    33721 ttaagaacgg gtttaagtct aaagctcatt agatttgcgg gttagagttt ctccgcccgg
    33781 ccggctgtac gcctggggtg tatgcgacgc gagagctaat ctctgggtgc gggatcaaac
    33841 aaatattgcg gaatgttacg aacatggtgt gcacacgcgc aatatgacgg ggtgtctttg
    33901 cacctgcgcc agctacaggg tttactagat tggtaatcca tctagagcga ccgagagacc
    33961 tggctcgacg acgtcgcagc aacctcgcct gcggtggcgc atcatgcgcc ctcataacgc
    34021 cgaaggtgct aacgccagca accgatggga gatactgtgg gactgcccag ccccttctcg
    34081 ttcacaaacc cgctagcccc tacccccaac cccgcgcatg aatctgatga ggcacgggta
    34141 gcgttctggg aaaaacaagc cgagcgccta agctggggca aggcctggga caacgcacat
    34201 accttccaga aaccgcaggt tatcggaacc gatgctgagg gcatcgaaga atactccgta
    34261 cccgagatta agtggttcga gggcggcaaa cttaacgtcg cctacaactg cgtggaccgc
    34321 cacgtggagg cgggccgcgg cgacaaagtg gccctctatt tcgagggtga acccggcgat
    34381 cgtgaagcta tcacctacgc cgaactgcag cgacgcatcg cccgcgccgc caacggcctg
    34441 ctcaaactcg gcgtgcgtaa aggcgaccgt gtagtaatct acctgccggt tattcccgaa
    34501 accattattt tcacgcttgc gtgcgcgcgg atcggcgcaa ttcattcgct cgtgttcggc
    34561 gggttctcgg cggaggcact gaagttccgg gtggaagaca ccggcgcgaa ggttctgatc
    34621 accaccgacg ggcagaaccg ccgcggcaag gtcgtgcccg tgaaggtgaa cgccgatgaa
    34681 gcatgctcgg gtgagaacaa tatcgagcat gtgatcgtgg tggaccgtac aagcgccgca
    34741 gaccccgtgg cgcacgcgca ggttccctgg acggccgggc gcgatatttg gtaccacgac
    34801 ctggtggacg atcagcccga tacccacgag tacgagctgc acgatgccga agacccgctg
    34861 tttatcatct atacctccgg caccacgggc aaacccaaag gcctggtgca cacaatggcg
    34921 gggtatttgg tgcaaaccgc atacacccac gcactgctgt acgatctgct gccggactat
    34981 gtggatgacg acggggtgct gcgccccgat gaactgtctg ccgtgaacga cccggcgaag
    35041 gttgaatcga ctgtgcactg gtgtaccgcc gatctcgcgt gggtgaccgc acacacctat
    35101 gaaatctatg gtccgcttgt gaatggggtg accgaggtta ttttcgaggg tacccccaat
    35161 actccgcatt acggccgtca tttcgaggtt atcgaacgct acggcgtcac caactattac
    35221 accgcgccca ccctgattcg ttccctcatg ggggcttttc ctgacggccc cgaacccgga
    35281 aaatacgact tctcaactgt gcgtctgctc gggtctgtgg gcgagtccat taaccctcag
    35341 gcgtggaagt ggctgcgcaa gcacgtgggc gggggtaccg catcgtttat cgatacgtgg
    35401 tggcagtccg aaaccggctc gaccatctgc tccccgcgac cacacgaccc cgccttcgca
    35461 cccgaaggga ccttccccga aggcaccccg cactgcactc cccttcccgg atgcgccacc
    35521 cgcgaagtcc ccggcgtctc ggtgcgcgtg gtggacgagc acggtgacct cgttgagccc
    35581 ggcaaacagg gcttcattgt ggtcgataag atcggcccct ccatggcacg cactgtctgg
    35641 ggcgacccgc aacgctacct gaattcctat tggaagcact acggtacgcg cggctggttc
    35701 ctcgccggtg acggcgcgaa ggtcgatgat gagggcaacg tgtatatttt ggggcgcatc
    35761 gacgatgtga tcaacatttc cgggcaccgc ctttcgacca tcgaaattga gtctgcgctc
    35821 gtgacgcacc cggccgtggt ggaggctggc gtgtgccccg tggaggacga gctaaccggc
    35881 caccaggcag tcgcctatgt gacgctcacc gacgaaggcc gggcactgac cgaagatgag
    35941 ctgaaggcgg cactcaccga gcatgtgcgc gagcatattg gtcctatcgc taaacccaag
    36001 gatgtggtcg cggtcgccga tattcctaag actcgttcag ggaagattac ccgccgcctg
    36061 ctgggcgagc tctaccaggg gcataagctg ggcgatattt cttcgcttca gaatgaggag
    36121 gcgctcggcg ctatcgcaca ggtactcgta gacaccgggc gagtaaaccc ggatgcgttc
    36181 accgaagagc aggcggcagc gtagggagcg catcgccaag cggtatgcac cctctttcga
    36241 gagcatactg gataagaaac gagcgcatta catattggga gcggtttctt gatggaggaa
    36301 ccgctcccac tttcgtcttg ttgcgtatcg ttagggtttt gagcctgttt ctgccccttt
    36361 atcagagggc tctggatccg attcgccggt ggctttagag ccttccgcgc tggagacctc
    36421 gccggggttt tcggcgctgc tatttttggt actggtgttt tcgctgctgg gcgcatccga
    36481 aacgttctgc ccggatgccc acgcaccttt atccaccggc ttggcgaaga agaggcacgc
    36541 gaccatgccc acggcggcca gagccagcgc cagaatcagt gagtcgttca tcgcggtggc
    36601 aataggttca cgcaggaaat cgggaacctg accgccggac atcccttcac cactgacggc
    36661 gggggcgctc atagcgcctc cgcctgcacc ggcacctgcg ggacgcatcc gctgcatggc
    36721 ctgtgtaacc tgctcggtaa tcaggccgcc catgaacgtg gcaatacccg ccgaaccaag
    36781 cacactggca acctggcgag tctcgttata cacgcccgac ccggcacccg ctaaacgagg
    36841 cggcaggttg cgggttgcgg tcaccgccag cggaccccaa atcatggagt tgccaatacc
    36901 caaaattgca aagggtacaa gcagaagcgc gagggactga tccgccgtca tcaaagcacg
    36961 cagaacaata aatccaacca ccagcagggc aaaccccgaa acggcgtacc atttggggtt
    37021 tgacgtgccc aaacgtttac caaccagcgg agagagagca cccgagaaca gggcgagcgg
    37081 ggcggtcatg agtgccgcct gggtggggct cataccgcgc acctgctgga aataaatagt
    37141 ggttgggaac gccagcgtca gggtgtgcgc gcccatcgcc gcgatagcaa tattagacac
    37201 cgaaaagttg cggtctttaa acagtcccag cggcaccagc ggctctttac ggttaacagc
    37261 ctgccacacg ataaagaggg tgaacacgat gatgcccgcg ataatcatgc cccatacgct
    37321 caccgggatt ccggttcccc acagcgactc ggtgataatg ccccagtcgt aggtagaacc
    37381 ctcctgaata ccaaagacca tcaggaacag gccgatagcg gaaagaacca cgcccagcca
    37441 gtcgaagttg tgctgtttgg agggaaaatg cgggatattc cgaaccgcca gatagatgcc
    37501 gatcacgccg atagggatat tgatgaagaa gatccacgtc cagccggggc catccacgag
    37561 cagaccgcca gcgatagggc ccacgagcga tgcgataccg gccgccgcac cccacacgct
    37621 catcgccacc ccacgtttat gcggcgggaa catgagcgta ataatcgaca tggtttgcgg
    37681 ggtcatcagg gaggcgccta tcccctgcac cacgcgcgca acaatcagca tctccacatt
    37741 gggcgagagc ccgcaccaca gcgaggagag ggtaaaaacc accataccaa gcaggtacat
    37801 ctgcttctgc ccgaacctat cgcccaggcg gccggtaatc agcagcggca ccgcataggc
    37861 gagcaggtaa gcactggtca cccagatcac ggcggagagc gaggcgttga gctcattctg
    37921 catatggggc agcgccacgg tgacgatagt ggtatcgagc aggatcataa agaacccgat
    37981 cacgagtgac cacatggcaa cccacggttt ctcggcggcg tgttcgatgg atggtgtgtg
    38041 tgggcgcttc ttcggcgcgg cttcttcagc cataaatccc ctgcctcatc ttctgtgcgg
    38101 taccgccgag cgataaaaac ctagcacttc atcatagctc tgtttgcgtt cacgaacgag
    38161 taggcgatgg tgatcctcgc agctgtgcct tcccggtgaa gacgtgcttt ctggcgtgcc
    38221 gcgcccgcgg cagcgagtct gctgttccaa tgtgcgcagg ccgcacccgc ccgttttctc
    38281 tttacgcgga agacgcgcgt gtagacatca ctacccagcg cacctagcct gaatatgtag
    38341 gctattttca ccaacatacg gaggagacga tggctgttgt aacgattatt ggcgggcacg
    38401 ggaaagttgc gcttctggcc gagccgctgc tggtggagcg cgggcacacg gtcaatgcgc
    38461 ttattcgcag gccggagcag tcagaggata ttgtcacgcg cggggcgaac ccggtggtca
    38521 ctgacattac cgcattgagc accgaggaga tggtgaagct tttgactgag ctgggaaccg
    38581 aggtgctggt gtggtccgcc ggtgcgggcg gcgtcggcgg gccggaacgc acctacgcgg
    38641 ttgaccgtga cgccgcgatc cggtcgatgg acgcggcacg gctggccggt attaaacggt
    38701 acgtgatggt atcgtacctg ggcgcgggtt ccgggcacgg catcgaccct gataacagtt
    38761 tttacgccta cgccgagtcg aaggcgatcg ccgatgaaca cctgcgcggc tcagggctgg
    38821 attacacgat cctggggccg gggatgctca cccttgagga ggcaggcggt attaccctgg
    38881 gggttgagcc cgcccacacg cccggcgccg aatctaatac tccgcgggcc accgttgccc
    38941 aggtgctggc ggcggttctt gaggacccgt ccacggttgg gaaggcgctc ccgtttattg
    39001 gcgggcccac cccgatcgct caggctctcg catcggcgcc taacagcaat aagctgcgct
    39061 agtacagtcc ccgtatgtgt ggcaggcggc ggcccggatt cgtgcaatcc gggccgcagt
    39121 tttagataat ggctatgagc acgagtaatg accggtaaag gggcgtccgt atgggcttct
    39181 tcagctattt caccgataaa acagctcccg aacctgccga ggcgcagctc accgcgtacg
    39241 tgagcgggcg ggtgcagggg gtggggttcc gctggtggtg cgctggcacc gccaaaccga
    39301 tgggtttgag cgggtacgcc gagaacctgg acgatggccg tgtgaaggtt atcgcgcagg
    39361 gaacccgcgc ctcctgcgag cacctgctgg atgcgctcaa ctcgggtgat acggctgggc
    39421 atgtggactt tgtggatgcc accttcagcg atccgcaggg cacgttcaag gggttcggga
    39481 tccggtagcg ctcctccact ccccatgcta aaaaggctct ttatgctccc gatgcacccc
    39541 gcagtatgcc cccaaatacc cggtaacgtg gaataatggt ctacgcactc atatcattca
    39601 cgtagttcat ggaggtcctt gatgacacgc tatcgctggg gcataaccgg tgcctgcatt
    39661 cttttcttag ctggagttat tgtttataac ctgcgcgaat ttctggcata tgattatctt
    39721 gtctattatg ccgggggtaa aagcgttaac tggtttcttg attaccccag taacctctat
    39781 gatctcgata ttcttcgtga aactgtgcgg gcagaaaact ttagatatat tttcggcgac
    39841 agcggcctgt ggcttgcgtt tacgtacccg ccgtttgcct cgctcctctt tattcccgca
    39901 tcgttcttgc ccctgcgggt ggcaattggc cttcatctgg catttttcgt acctattgcc
    39961 ttctattgcg ccaaggttct gcgtgactat ctggcaaagc gcaattctcg gctgcttttt
    40021 gagaaatatc tttcgccttt ttcctttatt gttttgtgtg ccgcgcttat cttactttca
    40081 gcgccgtggc gcaataattt cttgtacggt caaataaatc cgtatctgct ggtgcttatt
    40141 ctctacgatc ttctgcggcc gggtaccagg attccgcgcg gcgtttttat cggtattgct
    40201 gcgggcatta aacttactcc gctcgccata ggagttcttt ttctagtgcg taaagagtgg
    40261 aaatccatta ttgcactggg ggtctcgttt gcgggaacca ttgcggcggg gtttgctgtg
    40321 cttccgcagc agtctctcac ctattggggc agcgtcatct gggacccgtc acgcgtgggc
    40381 aacccgatat cgagcaatag catggcgatt caaggcgttt tagggcgcat gacctttcag
    40441 gatggtaccg tactgaaggc gctgtacggg atcgcggcaa tcgcgctaat tgcggtgata
    40501 gggtacgccc tgcggaagat ggagcagcac aacctctatc tatcgcagat ctcgttggcg
    40561 attcttgtgc cagtgtttat ctcaccaatc agctggttcc atcacgccgt gattctgccg
    40621 atttttatgg tgtgcgcggc ggtcgatttc ttgccgctgg tggcacggtg gcgttctcgt
    40681 gcggggcgca tcctgtgtta tctgtgctat gcgctgagtt ctctcatgct gattaatacg
    40741 cttctggact ggggaaagct cgtggtgcgc ttctggcggc gtgtcgattt ttacccattt
    40801 accggcaggt atccggggat ggatgcgcat accctgcttc tgcgggcggc ggatgagcag
    40861 ccggttatgt ttgtgacctc aattccagca ttggcgctcg tggtgttggt tgtgctgtgg
    40921 gcggtgctcc tacgccgccc tgctgaaagt agacaatgat aagaaggctc tttatgtgaa
    40981 taaagcatta gaaactccgc tttattcaca taaagagcct ttttacgcgg cggaaacggc
    41041 gagagaggcc aggatacgta cacccaacgc ctaatcacgc cagatttcgg cgaattgggc
    41101 gcgggtcatg gttgcttgcc gcacggcgac agccttccgg ttgccgtact tatcggggcg
    41161 ggccgcgctg gtgctggttt cgtcggtaat attcgtaaac ccggctttta ccgccacccg
    41221 ttcggatgct gcgtttccca ccagtgccgc ccatccgata gtgtctagtc ccagcccgag
    41281 cgggtcgaag ctgaagccga ggacggtgcg taccgcatcg gtcataatgc cgcgcccgcg
    41341 catctgggca gccgtataaa accctaagtc tgcatatgtt ccgggcgcgt ttgcggagcc
    41401 ttcgggcagg cgcagggaga tagcccctgc gagcaccccg ctgtcatcaa tggcccaggt
    41461 gagttcacgc ccggcggctg cggcgcgctg ggtgaaggtg aggaaggttt gcgcgtcgtc
    41521 gcgcgtgtag ttcaggggga cggtggtcca gcgcacggtt tcggggtcgg tgcagatctg
    41581 caccagttcg tcgaggtcag cttcacgcag gggcctgagg gtgaattttt cggtgatgag
    41641 ttcaggaatt ttcatggcac gagtatacac acaccataga gtgatacaaa acacatactc
    41701 agaggccctt gccaccttgt aattatgaat tactcataat aatatggagt tacttcccct
    41761 tcgagggcac caaaaataca gtttccgaaa gaccgcacac tatcgttcgg gagcttcaca
    41821 ccacaacctg aaagggcata aatggctgta ctatcc
//
