LOCUS       NZ_CP064192            21140 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Saccharothrix sp. 6-C chromosome, complete genome.
ACCESSION   NZ_CP064192
VERSION     NZ_CP064192.1
KEYWORDS    RefSeq.
SOURCE      Saccharothrix sp. 6-C
  ORGANISM  Saccharothrix sp. 6-C
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharothrix.
REFERENCE   1  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Saccharothrix texasensis strain 6-C
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) College of Life Sciences, Chongqing
            University, University Town Road, Chongqing, Chongqing 401331, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 10:20:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,916
            Genes (coding)                    :: 7,819
            CDSs (with protein)               :: 7,819
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 78 of 97
            Pseudo Genes (internal stop)      :: 6 of 97
            Pseudo Genes (multiple problems)  :: 27 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:34:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6258190
            Orig. end                         :: 6279330
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064192.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21140
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="34"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21140
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21140
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11140](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11140)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    153..168
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    complement(219..234)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.01"
                     /tool="antismash"
     gene            380..922
                     /locus_tag="IOD16_RS26145"
                     /old_locus_tag="IOD16_26010"
     CDS             380..922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945349.1"
                     /locus_tag="IOD16_RS26145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26010"
                     /product="hypothetical protein"
                     /protein_id="WP_123746471.1"
                     /transl_table=11
                     /translation="MELTPRALFGLARTTVETAVSVPGRVLDLLGAAEAVVRRADEMVT
                     RTERVLAETEALVGRAKAVTAAAEDVTTDVGRTARTSRELLDSYAPIAQKAQPLAQRFV
                     DDLSPHEVDAAVQLVDQLPVLTKHLIEDVLPILATLDRVGPDIHQLLEVTNDVRQAILG
                     IPGFTFMRRRGEAKEDD"
     misc_feature    complement(1124..1138)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            1209..1529
                     /locus_tag="IOD16_RS26150"
                     /old_locus_tag="IOD16_26015"
     CDS             1209..1529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012690132.1"
                     /locus_tag="IOD16_RS26150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26015"
                     /product="YciI family protein"
                     /protein_id="WP_123746470.1"
                     /transl_table=11
                     /translation="MKYMLLICVDGDIEPTEGDPTIEQWLAEVGDRRLDGSQLRSVQDA
                     TTVRTRGDEVLLSDGPFAETKEQIVGYDVVDCADLDEAIRIASRHPCARFGSVEVRPFY
                     TG"
     misc_feature    complement(1224..1237)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            1526..2743
                     /locus_tag="IOD16_RS26155"
                     /old_locus_tag="IOD16_26020"
     CDS             1526..2743
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1126:
                     extracytoplasmic-function sigma-70 factor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226537.1"
                     /locus_tag="IOD16_RS26155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26020"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_201436510.1"
                     /transl_table=11
                     /translation="MTVEAEVSELFRAERGRIVATLIRLTGDWDLAEECVQDAFARALE
                     CWPREGVPQRPGAWLTTTARNRALDRLRRSSVEAAKLREVVATPDDPPGEEDDGIGDDL
                     LRLVFTCCHPALTLEARVALTLRTVAGLTTPEIARAFLVPEATMAKRLVRARQKIRNAR
                     IPYRVPPAHLLPERTGGVLAVLYLLFNEGYAAGGGADLSRRDLCVEAIRLARTLVASMP
                     DEPEAVGLLALALLQDSRRDARFDHAGDLVPLDEQDRSRWDGAQVEEGVALLDSALRRG
                     RPGPYQVQAAIAACHATAARAQDTDWPQIALLYGELVKLVPSPVVRLNRAVAVAMADGP
                     AAGLALVDDLADEVTGHLLPATRADFLRRLGRGAEALAAYERARALAPTDAERRHLTRL
                     IGALGG"
     gene            complement(2780..3601)
                     /locus_tag="IOD16_RS26160"
                     /old_locus_tag="IOD16_26025"
     CDS             complement(2780..3601)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153186.1"
                     /locus_tag="IOD16_RS26160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26025"
                     /product="TIM barrel protein"
                     /protein_id="WP_201436511.1"
                     /transl_table=11
                     /translation="MPSRRTFLGTALATGAAVALPATASAAGHPRRRRVPKESISIQLY
                     TLRGIMGDDPEPVLSALADIGYRKVELAGTYGRSAAEFAAVLRRCGLRATSSHVGIDGD
                     LDQVIADARTLGHRYVVVPWVNHATLAEWRAFTARLEAAGDRLRRAGLSLGYHNHAHEF
                     AELAGVRPFDVITAGTTPRNVHLELDLYWAVTGGVDPVAVHRANFPRVRQFHVKDRAAD
                     GSFADPGTGTIDFAAIFRAANVTEYIVENDQPRDALVTARVGYDYLVDLRF"
     misc_feature    complement(3656..3671)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(3712..3728)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.2"
                     /tool="antismash"
     misc_feature    3728..3741
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.88"
                     /tool="antismash"
     misc_feature    complement(3730..3743)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.01"
                     /tool="antismash"
     gene            3830..5086
                     /locus_tag="IOD16_RS26165"
                     /old_locus_tag="IOD16_26030"
     CDS             3830..5086
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS26165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_26030"
                     /product="hypothetical protein"
                     /protein_id="WP_201436512.1"
                     /transl_table=11
                     /translation="MDVLPCGHAAYAADSRGCAHLVVERPPDHYGWFTGVGLAYDRLCE
                     ACAKRDDPPLIVLCVGCEERVEDYSELVGWLGRPEVRRHDADPGGTWTSADCAAEPLNA
                     WSVAALPGGWLVLTEAGLVRVDGTGTAFVAPVSLPVEPADLRSPDPPRPALHTSPDGRH
                     AAVVTDFGRHGVVLDLVAGAPVLTLDRGDYRYRQTCFPLAFVGSDRDAVVVAATDWNRL
                     DAIDLASGRLLTGRVTAWSGDGPKPEHYLDYFHGALLLDPSGRWLLDDGWVWSPSGVTL
                     VHDVAAWLGGDAHATEHGRQLAVREAWDVPMAWVDERTAVLQPIDRHDRPAVAGVEVHD
                     VVDARRVAAFAGPVGRMWGHDGLLYVGTAAGLEVWDPVDGARTGVVEGFTPIAHNPRTG
                     RFAELAAGRLRTWTPEPPP"
     gene            5244..5858
                     /locus_tag="IOD16_RS26170"
                     /old_locus_tag="IOD16_26035"
     CDS             5244..5858
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227638.1"
                     /locus_tag="IOD16_RS26170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26035"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_123746466.1"
                     /transl_table=11
                     /translation="MRETTAGPATGGYAKGRIRREDIITAAVAVYGEAGYHGSSLREIA
                     KRAGITHAGLLYYFPTKEALLAAVLERRDAEDAEREQLQAAPGVDVLRHFLALAEHNVR
                     HPGIVDLYSRLAAEAVAEDHPAHDYFVRHYRAAREGVVGSFRALADRGELRPGVDPAAA
                     ALTFVALMDGLQVQWLTTPDEVDLVGSLRFYLGGLLTVPLG"
     gene            complement(5839..6948)
                     /locus_tag="IOD16_RS26175"
                     /old_locus_tag="IOD16_26040"
     CDS             complement(5839..6948)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801782.1"
                     /locus_tag="IOD16_RS26175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26040"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_201436513.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3.3e-20, bitscore:
                     71.8, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.3e-21,
                     bitscore: 75.7, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPVGVGVVGTGVISDEYLRNLTAFPDVRVRAVADLDPERAAAR
                     AIRHGVPRSSTVEELLADPDIGIVVNLTVPAAHVAVSRAAVEAGKHVWVEKPLGLDLRG
                     TRDLLDLAARRGLRVACAPDTLLGAGWQTARRAVDAGRIGEPRTALALFQTPGPESWHP
                     APEFLFQAGGGPLLDMGPYYLTGLVHLLGPISRVTATGGRARDTRVIGSGPRAGVEFAV
                     TVPTTVTALVEFERGGTAQAVFSFDSALSRTGFVEVAGTLGTAVLPDPNGFGGATAVHL
                     FDGVQTLAPQGHQATRGTGVLELARAIRAGEPERASGELAYHVLDAMLAVERSIGSGRA
                     VDVGSTVEPPPALPVDWDPTATTLSRAGR"
     gene            complement(6945..7679)
                     /locus_tag="IOD16_RS26180"
                     /old_locus_tag="IOD16_26045"
     CDS             complement(6945..7679)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658467.1"
                     /locus_tag="IOD16_RS26180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26045"
                     /product="TIM barrel protein"
                     /protein_id="WP_201436514.1"
                     /transl_table=11
                     /translation="MSRTSVQLYSVRDAFAADPSDTLRRLAAIGFTHVEPYGVLENADV
                     LRTALPEHGLTAPTAHAQLIGADQAAVFAAAAECGIEVVIDPHVDAERWRDPADIAATA
                     SALNAAARVAAEHGVRVGYHNHWWELASRIDGRSAFEVLADRLDPEVVLEVDTYWATVG
                     GEDAPALLRRLGDRVHAIHVKDGGLAQDASGQVPAGQGRVPVAEVLAAAPHALRVVEFD
                     AYDGDLFAGLAESYAFLAEVAA"
     misc_feature    complement(7710..7724)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 27.15"
                     /tool="antismash"
     misc_feature    7711..7725
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     misc_feature    7762..7774
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            7877..8611
                     /locus_tag="IOD16_RS26185"
                     /old_locus_tag="IOD16_26050"
     CDS             7877..8611
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019359.4"
                     /locus_tag="IOD16_RS26185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26050"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_268957744.1"
                     /transl_table=11
                     /translation="MAKVAGMTVRTLHHYDELGLLRPGERTPSGHRRYTEADLHRLYQI
                     RLLRQLGMSLEEIGGVLTGAADAGPLARVLAAHLGQLDEQVWRLNALRRQTRGLLVQLS
                     GPTRPDPDRLLALLGSTTIFDGHLTREQRDFLDEHAFEVGPDARRRLDEEWPDVLAKVV
                     GHYRAGDPVDDPEVRRTARRLVDVGETFAAGDREILRSMGAFFRENGRGVLRDVLPGQP
                     VDDLGDGLWDYVARMYAALSAD"
     gene            8660..9838
                     /locus_tag="IOD16_RS26190"
                     /old_locus_tag="IOD16_26055"
     CDS             8660..9838
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672232.1"
                     /locus_tag="IOD16_RS26190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26055"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_236594394.1"
                     /transl_table=11
                     /translation="MPAAALAVLAATLTGVAEAEPGPDARPAPDLVLSLPAPTGPHHVG
                     VTALHLVDTERPDPWSGDGRPREVVVSVHYPASDVRDHPVAPQLTPGAAAAFPSYAPWG
                     FPHLPTSGVDWAATLTHSHVDAPARPGRRPVVLYSPGLVEPRAFGVNTAEEPASRGYVV
                     VTIDHPGETFTVDLPSGLRPVGLPGRPDADPPLYRAVIATRLADTDLVLDRLEVLAAGG
                     NPDAGGRALPRHLGRALDLRRVGMYGQGLGGTIAAEAMYEDQGGRIDAAINLEGFLDYH
                     PEQPGQDGELLPVARHGAGRPLLLIGTEGFRNDRYRRAWAAALAHDHVRQHVIADANHW
                     ALTDFAATVPQLHAAGLMDDAGRAAMVGALDPAVAVPTVRRHVVSFFDRALR"
     gene            complement(10001..11140)
                     /locus_tag="IOD16_RS26195"
                     /old_locus_tag="IOD16_26060"
     CDS             complement(10001..11140)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="IOD16_RS26195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26060"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_201436517.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-37, bitscore:
                     127.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTDAVRGDLAEVRAGVDATLDRFLAEKARTAPDPCLPPLVDVL
                     RGFVAGGPRLGPSACHCGFLAAGGSSDDPAVAWTGAALEMFHTFALVHDDIMSHAELRR
                     GRPTVHRALAERFPGVDGDPTAAERFGVNLAILAGDLCSTWTDELLDRAEVDRARWREV
                     RALLHTMRTELIAGQCLDLGGDPRSTADPVRSAWRMIRLKTARYAVELPLRVGVALAGG
                     GEAPTGGGEALTRFCGAYGRPVGEAFQLRDDLLGVFGDPEVPGRPSPQALRGGRPTVLM
                     ALARQQATPEQLEVISTLHGDPELDEERAARLRDVVVATGAVARVERLIKARADRASGA
                     LRSSATSPAAKASLAELVALTTRRPRSVTTPAQRTRSGT"
     misc_feature    11383..11396
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    11458..11476
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 20.83"
                     /tool="antismash"
     gene            11515..13281
                     /locus_tag="IOD16_RS26200"
                     /old_locus_tag="IOD16_26065"
     CDS             11515..13281
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103446.1"
                     /locus_tag="IOD16_RS26200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26065"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_201436518.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.7e-83,
                     bitscore: 278.1, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.2e-07, bitscore:
                     28.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTTLPGAARSPAPRITGPADLRGLSRGALDELARELRARLVE
                     AVGRTGGHLGSNLGVVELTVALHRVFRSPHDRVVFDTGHQSYVHKMLTGRADGFADLRR
                     EGGLSGYPSRAESPHDLVENSHASTALSYADGLARAARLRGEHDRHVVAVVGDGALTGG
                     MAWEALNNLGGLDHPVVVVLNDNGRSYAPTAGAVGRHLATLRAGGGGGVFAAFGLAYLG
                     PVDGHDVARVEEALTAAKALGRPVVVHCVTEKGKGHPPAENDPVDHLHAVSAPSASRGP
                     GWTSVFGRHLLVLADRHPDLVCLTAAMPHPTGLTAFAEAFPDRVLDTGIAEQHTVTCAA
                     GLAMGGLRPVVAVYSTFLTRAADQVLMDVALHRLPVTFVLDRAGVTGEDGPSHHGAWDL
                     ALLRGVPGMRVAAPRDGARLRELLDEAVADDGPTAVRFPKGVVGADVAAVDRLGRVDVL
                     HRPSRRDVLLVTVGGLASDGVAAAVALAGEGIGVTVCDPRWVTPVDPAVVALAAEHRVV
                     VCVEDGVRGGGVGEAVAGALREAGLSRRTRVLGLPDDFLPHGSRADILRMHDLDAAGIA
                     RTVARFLPGWTS"
     gene            complement(13327..14007)
                     /gene="lipB"
                     /locus_tag="IOD16_RS26205"
                     /old_locus_tag="IOD16_26070"
     CDS             complement(13327..14007)
                     /EC_number="2.3.1.181"
                     /GO_function="GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lipB"
                     /inference="COORDINATES: protein motif:HMM:NF010925.0"
                     /locus_tag="IOD16_RS26205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26070"
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="WP_201441582.1"
                     /transl_table=11
                     /translation="MRFVRGGFGRDAVGYEEAYAEQRRLHALRVADEIGDVCVLQEHLP
                     VYTAGKRTKAAAFPADDVPVVTVDRGGEITWHGPGQLVGYPVVKLPVPLDSVGHVRRLE
                     EALIGTCAEFGVATARLAGRSGVWVLGDRPPAPDVPPSAARAHGQHRKVAAIGVRIERC
                     TSLHGFGLNCDPDLTPFDRIVPCGIEDAGVTSLSAELGRRVTPTEVAPVVERHLTRVFA
                     TDRR"
     gene            complement(14061..14498)
                     /locus_tag="IOD16_RS26210"
                     /old_locus_tag="IOD16_26075"
     CDS             complement(14061..14498)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270: UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019589.4"
                     /locus_tag="IOD16_RS26210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26075"
                     /product="3-hydroxyacyl-ACP dehydratase"
                     /protein_id="WP_201436519.1"
                     /transl_table=11
                     /translation="MTYPEILRLLPHRHPVLLVDRVLDVVPGESLTALKAVSANEPCYA
                     RTGPGDYPSTLLVESWCQAAVLLSSWGNPAPDRVVLFGAIADVEFHRPVVPGCVVHHSV
                     RVLDRLADTTVFTGESTADGHLVMTVGRITTTTRTTTTLRP"
     gene            complement(14495..14857)
                     /locus_tag="IOD16_RS26215"
                     /old_locus_tag="IOD16_26080"
     CDS             complement(14495..14857)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019589.4"
                     /locus_tag="IOD16_RS26215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26080"
                     /product="beta-hydroxyacyl-ACP dehydratase"
                     /protein_id="WP_201436520.1"
                     /transl_table=11
                     /translation="MTGPLASGYLASGVEVLERSGSTTVARMVVAPDDPVFAGHFPGFP
                     IFPGVAVVEFAHRAATALGTARLAAVESARFVRPTFPGATLTVRLTWDDARRRCAAVVS
                     DDDGVVARIKLRYETS"
     gene            complement(14861..15832)
                     /locus_tag="IOD16_RS26220"
                     /old_locus_tag="IOD16_26085"
     CDS             complement(14861..15832)
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874750.1"
                     /locus_tag="IOD16_RS26220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26085"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_201436521.1"
                     /sec_met_domain="fabH (E-value: 2.5e-106, bitscore: 354.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRGAVILGVGASLPGRVVTNDDLAARLDTSDEWIRSRTGIGSR
                     RWVEPGTSTSDLAVDAGARALRSAGTSTADAVIVATTTPDRSCPAIAPDVAARLGMVGV
                     PAHDVAAVCTGFLYGLANAVGLIASGAARTVLLIAAETFSTILDPDDRGTAVIFGDGAG
                     AVVVGEGEGAIGPCVLGSDGTGADLIQVPAGERYFRMSGKEVFRAAVDRMSDVALDALA
                     RAGLGPDDVDHLAPHQANRRICDAVARRLGLADSKVLADLDEIGNTAAASIPVLLADAA
                     ATGRLKAGDRVLAVAFGGGLTWGATTLVWPDVTADFGVLGEG"
     gene            complement(15843..17054)
                     /locus_tag="IOD16_RS26225"
                     /old_locus_tag="IOD16_26090"
     CDS             complement(15843..17054)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (49-402). E-value:
                     1.4e-63. Score: 207.3. Matches aSDomain:
                     nrpspksdomains_IOD16_RS26225_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010307580.1"
                     /locus_tag="IOD16_RS26225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26090"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_201436522.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 9.5e-55, bitscore:
                     184.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 1.9e-125, bitscore: 417.7,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLDIAVTGLGLVTPGGVGVEAGWAAVRAGRSTAARDPLLAGHE
                     VTISCRVPDFDADALLGARRAVRLDRFTRLALVAAREAVAGEDLATWDSARVGVVIGTS
                     AGGGETFERQHGVLLADGPTGVSPLVLPMHLPNMVAGQVAIEFGFRGPNLVVSTACASG
                     ATAIGVACDLLAARRCDVVLAGGVDALLNPLTMAGFARMGALSRRDDPATASRPFDVDR
                     DGFVAGEGAAVLVLRRAEDARADGRRVRARVVGYGATADAHHITNPDPEGRGVAAATRA
                     ALADAGASASDVDHVNAHGTSTQLNDLVEGRVLAELLPSGPLVTSTKGVTGHLLGAAGA
                     AEAVFTVLAVEQGVVPPTANLTTLDPRLDLDVATAVVPRGIDLALSNSFGFGGQNAVLA
                     IAKA"
     aSDomain        complement(15849..16907)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS26225_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.40E-63"
                     /label="IOD16_RS26225_PKS_KS.1"
                     /locus_tag="IOD16_RS26225"
                     /protein_end="402"
                     /protein_start="49"
                     /score="207.3"
                     /tool="antismash"
                     /translation="CRVPDFDADALLGARRAVRLDRFTRLALVAAREAVAGEDLATWDS
                     ARVGVVIGTSAGGGETFERQHGVLLADGPTGVSPLVLPMHLPNMVAGQVAIEFGFRGPN
                     LVVSTACASGATAIGVACDLLAARRCDVVLAGGVDALLNPLTMAGFARMGALSRRDDPA
                     TASRPFDVDRDGFVAGEGAAVLVLRRAEDARADGRRVRARVVGYGATADAHHITNPDPE
                     GRGVAAATRAALADAGASASDVDHVNAHGTSTQLNDLVEGRVLAELLPSGPLVTSTKGV
                     TGHLLGAAGAAEAVFTVLAVEQGVVPPTANLTTLDPRLDLDVATAVVPRGIDLALSNSF
                     GFGGQNAVLAIAK"
     CDS_motif       complement(16557..16604)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS26225_0001"
                     /evalue="8.80E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="IOD16_RS26225"
                     /protein_end="166"
                     /protein_start="150"
                     /score="11.9"
                     /tool="antismash"
                     /translation="GPNLVVSTACASGATA"
     gene            complement(17041..17274)
                     /locus_tag="IOD16_RS26230"
                     /old_locus_tag="IOD16_26095"
     CDS             complement(17041..17274)
                     /GO_function="GO:0000035 - acyl binding [Evidence IEA]"
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (2-68). E-value: 1.2e-15.
                     Score: 49.5. Matches aSDomain:
                     nrpspksdomains_IOD16_RS26230_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="IOD16_RS26230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26095"
                     /product="acyl carrier protein"
                     /protein_id="WP_123746455.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-12, bitscore:
                     46.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYETLKKILVDTLKVAPEQITPDATKDDLDLDSLAFVELSMVLGK
                     EHDLHISDDELFDMETVGDIVALMRERAGDRP"
     aSDomain        complement(17071..17268)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS26230_PP-binding.1"
                     /evalue="1.20E-15"
                     /label="IOD16_RS26230_PP-binding.1"
                     /locus_tag="IOD16_RS26230"
                     /protein_end="68"
                     /protein_start="2"
                     /score="49.5"
                     /tool="antismash"
                     /translation="ETLKKILVDTLKVAPEQITPDATKDDLDLDSLAFVELSMVLGKEH
                     DLHISDDELFDMETVGDIVAL"
     gene            17385..18065
                     /locus_tag="IOD16_RS26235"
                     /old_locus_tag="IOD16_26100"
     CDS             17385..18065
                     /NRPS_PKS="Domain: PKS_KR (5-168). E-value: 1.5e-10. Score:
                     33.2. Matches aSDomain:
                     nrpspksdomains_IOD16_RS26235_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020500428.1"
                     /locus_tag="IOD16_RS26235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26100"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_201436524.1"
                     /transl_table=11
                     /translation="MADAPVAVVTGGNRGIGLEVCRQLAELGHVVVLTARDAAKARSAA
                     GRLGVDHHRLDVTEDASVAALVDHVTTRHGRLDVLVNNAAIHYDTWQRASSADLGVVRE
                     AMETNFYGPWRTVLGLLPLLRAARRARVVNVSSEAASLASMGGGTPAYGTSKAALNALT
                     LTLAAELPGMKVNAVCPGWVATDMGGPGGRPVARGAASVVWAATLPDDGPTGGFFRDGK
                     RVPW"
     aSDomain        17400..17888
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS26235_PKS_KR.1"
                     /evalue="1.50E-10"
                     /label="IOD16_RS26235_PKS_KR.1"
                     /locus_tag="IOD16_RS26235"
                     /protein_end="168"
                     /protein_start="5"
                     /score="33.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGGNRGIGLEVCRQLAELGHVVVLTARDAAKARSAAGRLGV
                     DHHRLDVTEDASVAALVDHVTTRHGRLDVLVNNAAIHYDTWQRASSADLGVVREAMETN
                     FYGPWRTVLGLLPLLRAARRARVVNVSSEAASLASMGGGTPAYGTSKAALNALTLTLAA
                     "
     CDS_motif       17406..17489
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS26235_0001"
                     /evalue="2.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IOD16_RS26235"
                     /protein_end="35"
                     /protein_start="7"
                     /score="23.2"
                     /tool="antismash"
                     /translation="VVTGGNRGIGLEVCRQLAELGHVVVLTA"
     gene            18088..18711
                     /locus_tag="IOD16_RS26240"
                     /old_locus_tag="IOD16_26105"
     CDS             18088..18711
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103794.1"
                     /locus_tag="IOD16_RS26240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26105"
                     /product="DUF4230 domain-containing protein"
                     /protein_id="WP_201436525.1"
                     /transl_table=11
                     /translation="MKWRIGVAAAVLVAVGVLVAAVLVVPRLLTGTDTIDRSQPALLQS
                     LRDLSQYHASAGEFQVVLDIERDVRYVPSALAGQRTLFVAAGTVNAYVDFGGLAEGALE
                     VSPTTASGEARKVRLALPKAVLDKPNLDQERCYVFAQERGLFDRLTSLVQTQDQQPFYV
                     AAEQKISDAARESGLAQRAEDNTRKMLTGMFGALGYQVEFTSLD"
     gene            complement(18695..19363)
                     /locus_tag="IOD16_RS26245"
                     /old_locus_tag="IOD16_26110"
     CDS             complement(18695..19363)
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680671.1"
                     /locus_tag="IOD16_RS26245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26110"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_201436526.1"
                     /transl_table=11
                     /translation="MSKAGAPLSRDRVLRAAVAIADAGGLAGLTMRSLGDALGVKPMSL
                     YHHVKNKDEILDGIVDLVFARMELPTPGGDWRHEMVKRADSARDVLKRHPWAIGLLESR
                     KAPGPATLRHHDATIGTLRRAGFSVAMTAHAYALLDSYVYGFAVQEAALPFNGPDSATE
                     VTADIMAHFGEGEYPHLVEMATEHVLRPGNDFADEFPFGLGVILDALAGWLPAEVSPGS
                     "
     gene            19468..20058
                     /locus_tag="IOD16_RS26250"
                     /old_locus_tag="IOD16_26115"
     CDS             19468..20058
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025687.4"
                     /locus_tag="IOD16_RS26250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_26115"
                     /product="DUF4386 domain-containing protein"
                     /protein_id="WP_201436527.1"
                     /transl_table=11
                     /translation="MSTRAIGRAMGALFLLAFVAYGTGTALVGSGSGARVAAGALLMLV
                     NSAVVVGIGVLAFPVLRPHGELTAHAYLVGRAAEAALLAVGVVFVLLPASAGVGAAGNH
                     YSYQVAMMAVGAVGVLFCRVLLRARLVHRAIAVWGVVGYAVFLLGAVLEVLGYGVGVAL
                     SVPGGLFEVALGVLLIARGFARSEVDREPALAG"
     gene            complement(20153..20371)
                     /locus_tag="IOD16_RS26255"
                     /old_locus_tag="IOD16_26120"
     CDS             complement(20153..20371)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS26255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_26120"
                     /product="hypothetical protein"
                     /protein_id="WP_201436528.1"
                     /transl_table=11
                     /translation="MVRLNPWSRGFGTAAAFAVLPAFFGVLLPARADGDVLALVGGILL
                     TAPAAGLLARGWWRCGSGNPRPGGRST"
ORIGIN
        1 gcaggacttc taccgcgacc ggatgcgcgc gcacggcgtc gaggtggtcg tcccggacga
       61 gccggaccgc acgctcgtgc acgacgtgat ctaccaggag ctgacccgcg accgggtcga
      121 gccggcgtcg cgcgccgcct accgggacgt gatggcacgc ctggtcgacc ggggcgcgga
      181 agcggtggtc ctgggctgca ccgagatcac cctgctggtc gaccagtccg acagcgccgt
      241 gccgctggtc gactccaccc gcgtccacgt cgaggcgggc gtcgacctcg cgctggcctg
      301 aggccggggc gggcacccgg atcgacggtc ggggatctcc ctgaggcccg ccacgtcggc
      361 gtgcggcaga gtggacggca tggagctcac cccgcgcgcc ctgttcggcc tggccaggac
      421 gaccgtcgag accgccgtgt cggtgccggg ccgcgtgctc gacctgctcg gcgcggcgga
      481 ggccgtcgtg cgccgcgccg acgagatggt cacccgcacc gagcgggtgc tggcggagac
      541 cgaggcgctg gtcgggcggg cgaaggcggt caccgcggcg gccgaggacg tcacgaccga
      601 cgtcggccgc accgcccgga cgtcacgcga gctgctggac agctacgcgc ccatcgcgca
      661 gaaggcgcag ccgctggctc agcggttcgt ggacgacctg tcgccccacg aggtggacgc
      721 cgccgtgcag ctggtggacc agctcccggt gctgaccaag cacctgatcg aggacgtgct
      781 gccgatcctg gccacgctgg accgcgtcgg accggacatc caccagctgc tggaggtcac
      841 caacgacgtc cggcaggcga tcctgggcat ccccggcttc acgttcatgc gccgccgcgg
      901 cgaggccaag gaagacgact aggcgcaccg ggaacgtcgc cggcgtgggt ggagctgctc
      961 ggcgaccggc gacccgaccc cgacgagcgg ttcgcactcg cgtcggttgc tcctcgtcga
     1021 gctcgggcgg atgcggccgc gtcaccgggc ggcttggcga cgggttccgg cgccgcgtcg
     1081 gacagcgcgg cgtcggcctc ggccgcggcc ggctcccccg ccgcggaaaa gatcttcaga
     1141 cggggtgtcc tcctcggcgg accccgttcg tcgtagtggt ggaatgcacc ggacgacagg
     1201 ggagaccgat gaagtacatg ctgctgatct gcgtcgacgg cgacatcgag ccgaccgagg
     1261 gcgacccgac catcgagcag tggctggccg aggtcgggga ccggcggctg gacggctccc
     1321 agctgcggtc ggtccaggac gccacgaccg tgcggacgcg cggtgacgag gtgctgctga
     1381 gcgacgggcc gttcgccgag acgaaggagc agatcgtcgg ctacgacgtc gtcgactgcg
     1441 ccgacctgga cgaggcgatc cggatcgcct cccggcaccc gtgcgcgcgg ttcgggtcgg
     1501 tcgaggtgcg gcccttctac accggatgac ggtcgaggcg gaggtctcgg agctgttccg
     1561 ggccgaacgg gggcggatcg tggcgacgct gatccgtctc accggcgact gggacctggc
     1621 cgaggagtgc gtgcaggacg ccttcgcgcg ggcgctggag tgctggccgc gcgaaggcgt
     1681 cccccagcgc cccggcgcgt ggttgaccac gaccgcccgc aaccgcgcgc tggaccggtt
     1741 gcggcggtcg agcgtggagg cggcgaagct gcgggaggtg gtggcgacgc cggacgaccc
     1801 gcccggggag gaggacgacg gcatcggcga cgacctgctg aggttggtct tcacgtgctg
     1861 ccacccggcg ttgacgctgg aggcgcgggt cgcgctgacc ctgcgcaccg tcgccggcct
     1921 gaccacgccg gagatcgcgc gggcgttcct ggtgccggag gcgacgatgg ccaagcggct
     1981 ggtgcgggcg cggcagaaga tccgcaacgc ccgcatcccg taccgggtgc cgccggccca
     2041 cctgctgccc gagcgcacgg gtggcgtgct ggctgtgctg tacctgttgt tcaacgaggg
     2101 ctacgcggcc ggcggtggcg ccgacctgtc gcggcgggac ctgtgcgtgg aggcgatccg
     2161 gctggcacgc acgctggtcg cttcgatgcc cgacgagccg gaggcggtcg ggctgctcgc
     2221 gctggcgctg ttgcaggact cccgccggga cgcgcggttc gaccacgcgg gcgacctcgt
     2281 gccgctcgac gagcaggacc ggtcccggtg ggacggcgcg caggtcgagg agggcgtggc
     2341 gctgctggac tcggcgctgc gccgcggccg gccgggtccg taccaggtgc aggccgccat
     2401 cgccgcctgc cacgccacgg ccgcgcgggc gcaggacacg gactggcccc agatcgccct
     2461 gctctacggc gagctggtca agctcgtccc gtcgccggtc gtgcggttga accgggcggt
     2521 ggccgtggcg atggcggacg gcccggcggc cgggctggcg ctggtggacg acctcgccga
     2581 cgaggtgacc ggtcacctgc tcccggccac cagggcggac ttcctgcggc gcctgggccg
     2641 cggggccgaa gcgctcgccg cctacgagcg ggcccgcgcc ctggccccga ccgacgccga
     2701 gcgccgccac ctcacccgcc tgatcggcgc gttgggcggg tgaggtggcg gcccgggagc
     2761 cgcgtctcgc gcgcgggcct cagaaccgca ggtccaccag gtagtcgtac cccacccggg
     2821 cggtgacgag ggcgtcgcgc ggctggtcgt tctccacgat gtactcggtc acgttcgcgg
     2881 cccggaagat ggccgcgaag tcgatcgtgc cggtgcccgg gtcggcgaac gacccgtcgg
     2941 ccgcccggtc cttcacgtgg aactgccgga ccctggggaa gttcgcccgg tgcaccgcca
     3001 ccgggtcgac cccgccggtc accgcccagt acaggtccag ctccaggtgc acgttgcgcg
     3061 gcgtcgtccc cgccgtgatc acgtcgaacg gccggacgcc cgccagctcg gcgaactcgt
     3121 gcgcgtggtt gtggtagccg aggctcagcc cggcgcgccg caacctgtcc cccgccgcct
     3181 ccaaccgcgc ggtgaacgcc cgccactccg ccagggtggc gtggttcacc cacggcacca
     3241 ccacgtaccg gtgcccgagg gtgcgcgcgt cggcgatcac ctggtcgagg tcgccgtcga
     3301 tgcccacgtg gctggacgtg gcccgcagcc cgcaccgccg cagcacggcg gcgaactcgg
     3361 ccgcgctgcg accgtacgtg ccggccagct cgaccttgcg gtaaccgatg tccgccagcg
     3421 ccgacagcac gggttccggg tcgtcgccca tgatcccgcg cagggtgtag agctggatgc
     3481 tgatcgactc cttcggcacg cggcggcggc gcgggtggcc ggcggcggac gcggtggcgg
     3541 gcagggcgac ggccgcgccg gtggcgaggg cggtgccgag gaacgtgcgg cgggacggca
     3601 tgggtgactc ctcgatcagc tgacgtcggt cgtccgggca tcgcggcgac ggccttgtgg
     3661 tccagctcac aacgcaaggc gtgcgccatt ctgttcagga tcaaccgaag ttcgcaagac
     3721 ttttgccagt tctagacaaa agtcagggcc gaacggccga agcccccgcc ctcgcgcgca
     3781 cggtccgtcg acaccgacgc cccggcccgc ggtggtccac aatgggccgg tggacgtgct
     3841 gccgtgcggg catgccgcgt acgccgccga ctcccgaggc tgcgcgcacc tcgtcgtgga
     3901 acggccccct gaccactacg ggtggttcac cggggtcggc ttggcctacg accggctctg
     3961 cgaggcgtgc gcgaagcggg acgacccgcc cctgatcgtg ctgtgcgtcg ggtgcgagga
     4021 gcgggtggag gactacagcg agctggtcgg ctggctcggc cggccggagg tccgccggca
     4081 cgacgccgat cccggaggca cgtggacgag cgccgactgc gcggcggaac cgctgaacgc
     4141 gtggagcgtg gcggccttgc ccggcggttg gctggtgctc accgaagccg gtctggtgcg
     4201 cgtcgacggg accgggacgg cgttcgtcgc gccggtgtcg ctgcccgtcg agccggcgga
     4261 cctgcgctcg cccgacccgc cgcgcccggc gctgcacacc tcgccggacg ggcggcacgc
     4321 cgcggtggtg accgacttcg gccggcacgg cgtcgtgctc gacctggtcg ccggcgcgcc
     4381 ggtgctgacc ctggaccggg gtgactaccg ctaccgccag acgtgcttcc cgctggcgtt
     4441 cgtcggctcg gaccgggacg cggtcgtcgt cgccgcgacc gactggaacc ggctcgacgc
     4501 gatcgacctc gcctccggcc ggctgctcac cgggcgggtg acggcgtggt cgggcgacgg
     4561 gccgaaaccg gagcactacc tggactactt ccacggcgcg ctgctgctcg acccgtcggg
     4621 gcggtggctg ctggacgacg gctgggtgtg gagcccgtcc ggcgtgacgc tcgtgcacga
     4681 cgtggcggcg tggctgggcg gcgacgcgca cgcgaccgag cacggcaggc agctcgccgt
     4741 gcgggaggcg tgggacgtgc cgatggcgtg ggtggacgag cgcaccgcgg tgctccagcc
     4801 gatcgaccgc cacgaccggc cggcggtggc cggcgtcgag gtgcacgacg tggtggacgc
     4861 gcggcgggtg gcggcgttcg ccggtccggt cgggcggatg tgggggcacg acggcctgct
     4921 ctacgtcggc acggcggcgg ggctggaggt ctgggacccc gtggacggcg cgcggacggg
     4981 cgtggtcgag ggcttcacgc cgatcgcgca caacccgcgc accggcaggt tcgccgaact
     5041 ggcggccgga cggctcagga cgtggacccc ggaaccacca ccgtgagccg ggcgccgccg
     5101 ggtcggagtc gtcgctccat gcgggaggtc cccttgatcc gcgcgcgggc ccacgtcgtg
     5161 ttctccggca ggtcgtcacc acccagcaca tctccgactg cgggctcacc cacctggccg
     5221 tcggcgtgcg gcatgatgtc cgcgtgcgcg agacgacggc gggccccgcg accggcggtt
     5281 acgcgaaggg ccgcatccgg cgcgaggaca tcatcaccgc ggcggtcgcg gtgtacgggg
     5341 aggccgggta ccacgggtcg tcgttgcgcg agatcgccaa gcgcgccggg atcacgcacg
     5401 cggggctgct gtactacttc cccaccaagg aagcgctgct cgccgcggtg ctggagcgcc
     5461 gtgacgcgga ggacgccgag cgggagcagc tccaggccgc tcccggcgtc gacgtcctgc
     5521 gccacttcct cgccctggcc gagcacaacg tgcgccaccc cggcatcgtc gacctctact
     5581 cgcggctggc cgccgaggcc gtcgccgagg accacccggc gcacgactac ttcgtccgcc
     5641 actaccgggc ggcccgcgag ggcgtggtcg gctcgttccg ggccctcgcg gaccgcggcg
     5701 aactccgccc cggcgtcgac ccggcggcgg cggcgctgac gttcgtcgcg ttgatggacg
     5761 gcttgcaggt ccagtggctg accacgccgg acgaggtcga cctggtcggc tcgttgcggt
     5821 tctacctcgg cggcctgctc accgtcccgc tcggctgagg gtcgtcgcgg tcgggtccca
     5881 gtcgaccggc agggcgggtg gcggctcgac cgtgctgccg acgtccaccg cgcgccccga
     5941 cccgatggac cgctccacgg ccagcatggc gtccagcacg tggtacgcga gctcgccgga
     6001 ggcgcgttcc ggctcgccgg cccggatcgc ccgcgccagc tccagcacac ccgtgccgcg
     6061 cgtcgcctgg tgcccctgcg gcgcaagcgt ttgcacgccg tcgaacaggt gcaccgcggt
     6121 cgcgccgccg aagccgttcg ggtcgggcag cacggcggtg cccagcgtcc cggcgacctc
     6181 cacgaaaccc gtgcgggaca acgccgagtc gaagctgaac acggcctgcg cggtgccgcc
     6241 gcgctcgaac tcgaccaggg cggtcaccgt ggtcggcacg gtcaccgcga actcgacgcc
     6301 cgcgcgcggc ccggagccga tcacccgcgt gtcccgggcc cgaccgccgg tggcggtgac
     6361 ccggctgatc gggccgagca ggtgcaccaa cccggtcagg tagtacggcc ccatgtcgag
     6421 caacggcccg ccgcccgcct ggaacaggaa ctccggcgcg gggtgccagc tctccgggcc
     6481 cggcgtctgg aacagggcca gcgcggtgcg cggctcgccg atgcgcccgg cgtcgacggc
     6541 ccgccgcgcg gtctgccacc cggcgccgag cagggtgtcg ggcgcgcacg cgacgcgcag
     6601 gccccgccgt gcggccaggt cgagcaggtc gcgcgtgccg cgcaggtcca gcccgagcgg
     6661 tttctccacc cagacgtgct tcccggcctc gaccgcggcc cggctgaccg cgacgtgcgc
     6721 ggcgggcacg gtcaggttga ccacgatccc gatgtccggg tcggccagca gctcctccac
     6781 agtggacgat cgcggcacgc cgtgccggat cgcccgcgcc gccgcgcgtt ccgggtcgag
     6841 gtcggccacg gcccgcaccc gcacgtccgg gaaagcggtc aggttgcgca ggtactcgtc
     6901 gctgatgacg cccgtgccga cgaccccgac gccgaccggg gcgctcacgc cgcgacctcg
     6961 gcgaggaacg cgtagctctc ggccaggccg gcgaacaggt cgccgtcgta ggcgtcgaac
     7021 tcgaccacgc gcagcgcgtg cggcgcggcg gccagcacct ccgccaccgg cacgcgcccc
     7081 tgaccggccg ggacctggcc cgacgcgtcc tgcgcgagac cgccgtcctt gacgtggatc
     7141 gcgtgcacgc ggtcgccgag gcggcgcagc aacgcgggcg cgtcctcgcc gccgaccgtc
     7201 gcccagtagg tgtcgacttc cagcaccacc tcggggtcga ggcggtcggc cagcacctcg
     7261 aacgcgctgc ggccgtcgat ccgggacgcc agctcccacc agtggttgtg gtagccgacg
     7321 cggacgccgt gctcggcggc gacccgggcg gcggcgttga gcgcggacgc ggtggcggcg
     7381 atgtcggccg ggtcccgcca gcgctcggcg tccacgtgcg ggtcgatcac cacctcgatg
     7441 ccgcactcgg ccgcggcggc gaagacggcg gcctggtcgg cgccgatgag ctgcgcgtgc
     7501 gcggtcggcg cggtgaggcc gtgctcgggc aaggcggtgc gcagcacgtc ggcgttctcc
     7561 aggacgccgt agggctcgac gtgggtgaag ccgatggcgg cgaggcgccg cagggtgtcg
     7621 gagggatcgg ccgcgaacgc gtcgcggacg gagtagagct gcacggaggt cctgctcatc
     7681 acgggctcct gacgtcgtcg tcggcatgcg tggaagcgct cccacagatt tctaccacct
     7741 ggtagaaatt cgcgctacgg cgtgccgtcg tcacccgtcc gggcaatgga cttgaacctg
     7801 acgccacgtg aggttccagg gtcggtgcca tgagcgctga gggtgcctcg accagccgcg
     7861 gtggagcgtc ggcgccctgg ccaaggtcgc cgggatgacg gtccggacgc tgcaccacta
     7921 cgacgagctg ggcctgctgc ggcccggcga gcgcacgccg tccggccacc ggcgctacac
     7981 cgaggcggat ctgcaccggc tctaccagat ccggctgctg aggcagctcg gcatgtcgtt
     8041 ggaggagatc ggcggcgtgc tgaccggcgc ggccgacgcc gggccgctcg cccgggtgct
     8101 cgccgcgcac ctgggacagc tggacgagca ggtgtggcgg ctcaacgcgc tgcgccgcca
     8161 gacgaggggt ctgctcgtcc agctgagcgg gccgacccgg ccggaccccg accggctcct
     8221 cgccttgctg ggcagcacca cgatcttcga cgggcacctc acccgggaac agcgcgactt
     8281 cctggacgag cacgccttcg aggtcggccc ggacgcccgc aggaggctcg acgaggaatg
     8341 gcccgacgtg ctcgcgaagg tggtcgggca ctaccgcgcg ggcgacccgg tggacgaccc
     8401 ggaggtccgc cggaccgccc ggcgcctggt cgacgtcggc gagacgttcg ccgccggcga
     8461 ccgggagatc ctgcgctcga tgggggcgtt cttccgggag aacggccggg gcgtgctgcg
     8521 ggacgtgctg ccggggcagc cggtggacga cctcggcgac ggcctgtggg actacgtggc
     8581 ccgcatgtac gcggcgctgt cagccgactg aagaactgcc cggaaccgaa cagggggaga
     8641 catgttccac aggacgagtg tgcccgcagc ggccctggcg gtcctcgccg cgacgctgac
     8701 cggcgtcgcc gaggccgagc cgggcccgga cgcgcgcccg gccccggacc tggtcttgag
     8761 cctgcccgcg ccgaccggcc cgcaccacgt cggcgtcacc gcgctgcacc tggtcgacac
     8821 cgagcggccg gacccgtggt ccggtgacgg ccggccgcgc gaggtggtgg tctcggtgca
     8881 ctaccccgcg tcggacgtcc gcgaccaccc ggtcgcgccg cagctgacgc cgggcgcggc
     8941 ggcggcgttc ccgtcgtacg cgccgtgggg gttcccgcac ctgccgacca gcggcgtgga
     9001 ctgggccgcc acgctcaccc actcgcacgt ggacgcgccg gcgcgtcccg ggcgccgacc
     9061 ggtcgtgctc tacagccccg ggttggtcga gccgcgcgcg ttcggcgtga acaccgccga
     9121 ggagccggcg agccggggct acgtcgtggt gacgatcgac caccccggcg agaccttcac
     9181 cgtcgacctg ccgtccgggc tgcggccggt cggcctgccc ggtcggcccg acgcggatcc
     9241 gccgctctac cgggcggtga tcgccacccg gctcgcggac acggacctcg tgctcgaccg
     9301 gctggaggtc ctggcggcgg gcggcaaccc cgacgccggg ggccgcgcgc tcccgaggca
     9361 cctcggccgc gccctcgacc tgcgtcgggt cggcatgtac ggccaggggc tgggcggcac
     9421 gatcgccgcc gaggcgatgt acgaggacca gggcgggcga atcgacgcgg cgatcaacct
     9481 ggagggcttc ctggactacc acccggagca gcccggccag gacggcgagc tgctgcccgt
     9541 cgcccggcac ggagccggcc ggccgttgct gctgatcggc accgagggct tccggaacga
     9601 ccgctaccgg cgcgcgtggg cggcggcgct cgcgcacgac cacgtccggc agcacgtgat
     9661 cgccgacgcg aaccactggg cgttgaccga cttcgccgcc accgtgccgc aactgcacgc
     9721 ggcgggcttg atggacgacg ccgggcgcgc ggcgatggtc ggcgcgctcg acccggccgt
     9781 cgcggtgccg accgtgcgcc ggcacgtggt gtccttcttc gaccgcgccc tgcgctagga
     9841 ccgcagggcc gccaccgcgg cggccgggtg gtcggccgtg atgccggtgg ccggcgccgg
     9901 cccgcgcgcc gggttcgacc aggcccgccg caccgcccac agcggcctca ccgggtcgac
     9961 gtcggccgga cccgaaggag ccgcccggct cgtcgaaggc tcacgtgccg ctgcgcgtgc
    10021 gctgggccgg tgtggtcacg ctcctcggcc ggcgggtcgt gagggcgacc agctccgcca
    10081 gcgacgcctt ggcggccggg ctcgtcgccg acgaccgcag cgcgcccgac gcccggtccg
    10141 cgcgggcctt gatcagccgt tccacccggg ccaccgcccc ggtcgcgacc accacgtcgc
    10201 gcagccgcgc ggcccgctcc tcgtccagct ccggatcgcc gtgcagggtc gagatcacct
    10261 cgagctgctc gggggtggcc tgctgccggg ccaaggccat cagcacggtc ggcctgccgc
    10321 cgcgcagggc ctgcggggaa ggcctgccgg gcacctcggg gtcgccgaac acgccgagca
    10381 ggtcgtcgcg cagctggaac gcctcgccga ccggcctccc gtacgcgccg cagaaccggg
    10441 tcagcgcctc gccgccgccg gtgggcgcct cgccgccgcc ggccagcgcc acgccgacgc
    10501 gcaacggcag ctccaccgcg taccgggcgg tcttgagccg gatcatccgc cacgccgacc
    10561 gcaccgggtc cgccgtggag cgcgggtcgc cgccgaggtc gaggcactgc ccggcgatca
    10621 gctcggtgcg catggtgtgc agcagcgcgc gcacctcgcg ccaccgcgcc cggtcgacct
    10681 cggcccggtc cagcagctcg tcggtccacg tggagcacag gtcgcccgcc aggatggcga
    10741 ggttcacgcc gaaccgctcg gccgccgtcg ggtcgccgtc gacaccgggg aaccgctcgg
    10801 cgagcgcccg gtgcacggtc ggccggccgc gccgcagctc ggcgtggctc atgatgtcgt
    10861 cgtgcaccag cgcgaaggtg tggaacatct ccagcgccgc gccggtccac gccaccgcgg
    10921 gatcgtcgga cgagccgccc gcggcgagga aaccgcagtg gcacgccgag ggtcccaacc
    10981 gcgggccgcc ggccacgaac ccgcgcagca cgtccaccag cggcggcagg cacgggtcgg
    11041 gcgcggtgcg cgccttctcc gccaggaagc ggtcgagcgt cgcgtccacc ccggcgcgga
    11101 cctcggcgag gtcgccgcgc acggcgtcgg tgacagtcat ggaacctcca cgagcacgga
    11161 caggaccggc ttccggtgag cacgcgcgga gcgggcgcgc gtcgggtgcg cacggccgcg
    11221 gtccagcggc cggacgtggc cacctcccgg cgctctcgaa gctaacaccg gcggggcggg
    11281 accgacgccc gacgacccgt tcggggaccg tcccacctgc gtctccggcc cttgggcgac
    11341 gacgtcggaa gcagcggttc cccgttttcc gcgaaccaca cgcacacgtc cgtgtggcgc
    11401 ccgcgatctc gttcgcgtga aacgcggcgg cccgcttgtc ccggccggcc gggtgcggca
    11461 ggttcgcctc accccacgtt gccgcaaggc cttcgcaccg cctggagtgg cctgatgacc
    11521 gacaccacca ccctgcccgg ggccgcccgg tcccccgcgc cccggatcac cggcccggcc
    11581 gacctgcgcg gcctgtcgcg cggcgcgctg gacgagctgg cgcgcgagct ccgggcacgc
    11641 ctggtcgagg cggtgggccg cacgggcggc cacctcggct cgaacctcgg ggtggtcgag
    11701 ctgacggtgg cgctgcaccg ggtgttccgg tcgccgcacg accgggtcgt gttcgacacc
    11761 ggtcaccagt cctacgtgca caagatgctc accggccggg ccgacgggtt cgccgacctg
    11821 cgccgcgagg gcggcctgtc cggttacccg agccgggcgg agtcgccgca cgacctggtg
    11881 gagaactcgc acgcgtccac cgcgctgtcc tatgcggacg gtctggcgcg ggcggcgcgg
    11941 ctgcgcggcg agcacgaccg gcacgtggtg gccgtcgtcg gcgacggcgc gctcaccggc
    12001 ggcatggcgt gggaggcgct gaacaacctc ggcggcctcg atcacccggt cgtggtggtg
    12061 ctcaacgaca acggccggtc gtacgcgccg acggcgggcg cggtcggcag gcacctcgcc
    12121 accctgcgcg cgggcggcgg cggaggcgtg ttcgccgcct tcgggttggc ctacctcggc
    12181 ccggtcgacg ggcacgacgt cgcccgggtg gaggaggcgt tgaccgccgc gaaggcgttg
    12241 gggcgcccgg tcgtcgtgca ctgcgtgacc gagaagggca agggtcaccc gcccgcggag
    12301 aacgacccgg tggaccacct gcacgccgtg tccgcgccgt cggcctcgcg cggtccgggg
    12361 tggacgtcgg tgttcgggcg gcacctgctg gtgctcgccg accggcaccc cgacctggtg
    12421 tgcctgaccg cggccatgcc gcacccgacc gggctgaccg cgttcgccga ggcgttcccc
    12481 gaccgggtgc tcgacaccgg gatcgccgag cagcacaccg tgacgtgcgc ggcgggcctg
    12541 gccatgggcg ggctgcggcc ggtggtggcg gtgtactcga cgttcctgac ccgggcggcc
    12601 gaccaggtgc tgatggacgt ggcgctgcac cggctgccgg tgacgttcgt gctcgaccgg
    12661 gccggggtga ccggtgagga cggtcccagc caccacggcg cgtgggacct ggcgctgctg
    12721 cgcggcgtgc ccgggatgcg ggtggccgcg ccccgggacg gcgctcggct gcgcgagctg
    12781 ctggacgagg cggtcgccga cgacgggccg accgcggtcc gcttccccaa gggcgtcgtc
    12841 ggcgcggacg tcgccgcggt ggaccggttg ggccgggtgg acgtgctgca ccggccgtcg
    12901 cggcgggacg tgctgctggt gaccgtcggc gggctcgcgt ccgacggggt ggccgccgcc
    12961 gtggcgctcg ccggcgaagg catcggcgtg accgtgtgcg acccgcgctg ggtgaccccg
    13021 gtcgacccgg cggtggtggc gttggccgcc gagcaccggg tggtggtgtg cgtggaggac
    13081 ggcgtgcgcg gcggcggcgt cggggaggcg gtggccggcg cgctgcgcga ggccgggctg
    13141 agccgccgca cccgggtgct cgggctgccg gacgacttcc tgccgcacgg ctcgcgtgcc
    13201 gacatcctgc gcatgcacga cctggacgcc gccggcatcg cccgcacggt ggcccgcttc
    13261 ctgccggggt ggacgtcgtg acgcgcttct cgccacctgc gtccggcggt caccggcggt
    13321 cggcggtcac cggcggtcgg tcgcgaacac cctcgtcagg tggcgttcga ccaccggcgc
    13381 cacctcggtc ggcgtgaccc ggcggccgag ttcggcggac aacgacgtga cgccggcgtc
    13441 ctcgatgccg cagggcacga tccggtcgaa cggggtcagg tcgggatcgc agttgagccc
    13501 gaacccgtgc aggctggtgc accgctcgat gcggacgccg atcgcggcga ccttgcggtg
    13561 ctgcccgtgg gcgcgggccg cggacggcgg cacgtccggc gcgggcggtc ggtcgccgag
    13621 cacccacacg ccgctgcgcc cggcgagccg tgccgtcgcc acgccgaact cggcgcacgt
    13681 gccgatcagc gcctcctcca gcctgcggac gtggccgacg gagtccaggg gcacgggcag
    13741 cttcaccacg gggtagccga cgagctggcc cggaccgtgc caggtgatct ccccgccgcg
    13801 gtccaccgtc accaccggca cgtcgtcggc ggggaacgcg gcggccttcg tgcgcttgcc
    13861 cgccgtgtac acgggcaggt gctcctggag cacgcagacg tcaccgatct cgtccgccac
    13921 gcgcaacgcg tgcaacctcc gctgctccgc gtacgcctcc tcgtacccga ccgcgtcccg
    13981 cccgaaccca ccgcgcacga accgcatcgc acccacggtc acgagtctag gtacctctcg
    14041 gggcggaggt cggcggccga tcacgggcgg agggtggtgg tggttcgggt ggtggtggtg
    14101 atccggccca cggtcatcac gaggtggccg tcggcggtcg actcgccggt gaagacggtc
    14161 gtgtcggcga ggcggtccaa gacgcgcacc gagtggtgga cgacgcagcc ggggacgacc
    14221 ggccggtgga actccacgtc cgcgatcgcg ccgaacagga cgacgcggtc gggggccggg
    14281 ttgccccagg acgacagcag cacggcggcc tggcaccagg attcgaccag cagcgtcgac
    14341 gggtagtcgc cgggacccgt gcgggcgtag cagggttcgt tggcgctgac cgctttgagc
    14401 gcggtcagcg actcgcccgg caccacgtcc agcacgcggt cgaccagcag caccgggtgg
    14461 cggtgcggca ggagccggag gatctcgggg taggtcatga cgtctcgtag cgcagcttga
    14521 tccgggcgac cacgccgtcg tcgtcgctca ccaccgccgc gcaccgccgt cgcgcgtcgt
    14581 cccaggtcag gcgcacggtc aaggtggcgc cggggaacgt cggccgcacg aaccgggccg
    14641 attcgacggc ggccagccgc gccgtgccga gagcggtcgc cgcgcggtgg gcgaactcca
    14701 ccaccgcgac gccggggaag atcgggaagc ccgggaagtg gcccgcgaac accgggtcgt
    14761 cgggcgcgac gaccatgcgc gcgacggtgg tcgaaccgga ccgctccagc acttccacgc
    14821 ccgacgcgag gtagcccgac gcgagtggac cggtcaccgg tcagccttcc ccgagcacgc
    14881 cgaagtcggc ggtcacgtcc ggccacacga gcgtggtcgc gccccaggtg agcccgccgc
    14941 cgaaggccac cgccagcacc cggtcgcccg ccttgagccg gccggtcgcg gcggcgtcgg
    15001 ccagcagcac ggggatcgag gcggcggcgg tgttgccgat ctcgtccagg tccgccagca
    15061 ccttcgagtc cgccaggccg aggcggcgcg cgacggcgtc gcagatgcgc cggttcgcct
    15121 ggtgcggcgc gaggtggtcg acgtcgtccg ggccgaggcc ggcgcgggcc agggcgtcca
    15181 gcgcgacgtc cgacatccgg tcgaccgcgg cccggaacac ctccttgccg ctcatccgga
    15241 agtagcgctc ccccgccggc acctggatca ggtcggcccc ggtgccgtcg ctgccgagca
    15301 cgcacgggcc gatcgcgcct tcgccctcgc cgacgaccac cgcgcccgcg ccgtcgccga
    15361 agatgaccgc cgtgccgcgg tcgtccgggt cgaggatggt ggagaaggtc tcggcggcga
    15421 tcagcagcac ggtccgcgcc gcgccgctcg cgatcaggcc gaccgcgttc gccaggccgt
    15481 acaggaagcc ggtgcacaca gcggccacgt cgtgcgccgg cacgccgacc atgcccagcc
    15541 gggccgcgac gtccggcgcg atggccgggc acgaccggtc cggggtggtc gtcgccacga
    15601 tcaccgcgtc cgcggtggac gtcccggcgg agcgcagggc ccgcgcgccc gcgtcgacgg
    15661 ccaggtccga cgtggacgtg cccggctcga cccacctgcg ggagccgatg ccggtgcgcg
    15721 accggatcca ctcgtccgag gtgtccaagc gggccgccaa gtcgtcgttg gtgacgaccc
    15781 gtccgggcag gctcgcgccg acgccgagga tcaccgcacc gcggtaggtc atcgtccctc
    15841 cctcacgcct tggcgatggc cagcacggcg ttctgcccgc cgaacccgaa cgagttgctc
    15901 aacgccaggt cgatcccgcg cggcacgacg gcggtcgcca cgtcgaggtc cagccggggg
    15961 tcgagggtcg tcaggttcgc ggtcggcggc acgacgccct gctcgaccgc gagcacggtg
    16021 aacaccgcct ccgccgcgcc ggccgcgccg agcaggtgcc cggtcacgcc cttggtcgac
    16081 gtcaccagcg gcccagacgg cagcagctcc gccagcaccc gcccctccac caggtcgttg
    16141 agctgcgtgg acgtgccgtg cgcgttgacg tggtcgacgt ccgaggccga cgcgcccgcg
    16201 tccgccaacg ccgctctcgt cgccgcggcc acgccccggc cctcggggtc ggggttggtg
    16261 atgtggtggg cgtcggcggt cgcgccgtac ccgacgaccc gcgcccggac ccgccgcccg
    16321 tcggcgcgcg cgtcctccgc gcgccgcagc accagcaccg ccgcgccctc ccccgccacg
    16381 aacccgtccc ggtcgacgtc gaacggccgg gacgcggtcg ccgggtcgtc ccgccgcgac
    16441 agcgcgccca tccgggcgaa ccccgccatg gtcagcgggt tgagcagcgc gtcgacgccg
    16501 ccggccagca ccacgtcgca ccggcgcgcg gcgagcaggt cgcacgcgac gccgatcgcg
    16561 gtggccccgg acgcgcacgc ggtcgacacc accaggttcg gcccgcggaa gccgaactcg
    16621 atggcgacct ggcccgcgac catgttcggc aggtgcatcg gcagcaccag cggcgacacc
    16681 ccggtcgggc cgtcggcgag cagcaccccg tgctgccgct cgaaggtctc gccgccgccc
    16741 gccgaggtgc cgatcaccac gccgaccctg gccgagtccc acgtggcgag gtcttccccg
    16801 gcgaccgcct cccgcgccgc gaccagcgcc aacctggtga accggtcgag ccggacggcc
    16861 cgccgcgcgc cgagcagcgc gtcggcgtcg aagtcgggga cgcggcagga gatcgtcacc
    16921 tcgtggccgg cgagcagcgg gtcgcgggcg gcggtggacc ggcccgcgcg caccgccgcc
    16981 cagccggcct cgaccccgac gccgcccggg gtgaccaggc cgagcccggt caccgcgatg
    17041 tcaaggccgg tcaccggcgc gctcccgcat cagcgccacg atgtcgccga cggtctccat
    17101 gtcgaacagc tcgtcgtcgc tgatgtgcag gtcgtgctcc ttgccgagca ccatcgacag
    17161 ctccacgaac gccagcgagt ccaggtcgag gtcgtccttc gtggcgtccg gggtgatctg
    17221 ctccggcgcg accttcagcg tgtccacgag gatcttcttc aacgtctcgt acacggcgat
    17281 ctcccaaagt ccacccggat cctgcccgtc atcgaacctc atcggccgga tcggtggcca
    17341 accagggaga atgtcggcgg ggtgcgactc tgggggagga cggcatggcg gacgcgccgg
    17401 tggcggtcgt gacgggcggg aaccggggca tcgggctgga ggtgtgccgg cagctggcgg
    17461 agctcggcca cgtcgtggtg ctgaccgcgc gcgacgcggc caaggccagg tcggcggccg
    17521 gacggctggg cgtggaccac caccggttgg acgtgaccga ggacgcgtcg gtggccgcgc
    17581 tggtcgacca cgtgaccacg cggcacggcc ggctggacgt gctggtgaac aacgcggcca
    17641 tccactacga cacctggcag cgggcgtcct cggccgatct gggggtcgtc cgggaggcca
    17701 tggagaccaa cttctacggg ccgtggcgca cggtcctcgg cctgctgccg ctgctgcggg
    17761 cggcccggcg cgcgcgggtg gtgaacgtgt cgagcgaggc cgcgtcgttg gcgtcgatgg
    17821 gcggcggcac gccggcttac gggacgtcga aggcggcgtt gaacgcgttg accttgacgt
    17881 tggccgccga actgcctggg atgaaggtca acgcggtgtg cccggggtgg gtcgccactg
    17941 acatgggcgg acccggcggg cggccggtgg cgcggggcgc ggcgagcgtg gtgtgggcgg
    18001 cgacgctgcc cgacgacggg ccgacgggcg ggttcttccg cgacgggaag cgggttccct
    18061 ggtagcgcgc cggggtaacc cggcggcatg aagtggcgca tcggtgtggc ggcggcggtg
    18121 ctggtggcgg tcggggtcct ggtggcggcg gtgttggtgg tgccccggtt gttgacgggc
    18181 acggacacga tcgaccgcag ccagccggcg ttgttgcagt cgttgcggga cctgagccag
    18241 taccacgcgt cggcgggcga gttccaggtg gtgctcgaca tcgagcgcga cgtccggtac
    18301 gtgccgtcgg cgctggccgg gcagcggacg ctgttcgtgg cggccgggac ggtgaacgcc
    18361 tacgtcgact tcggcgggct ggccgagggc gccttggagg tgtcgccgac gaccgcgtcc
    18421 ggcgaggcgc ggaaggtccg gttggcgctg cccaaggcgg tgctggacaa gccgaacctc
    18481 gaccaggagc ggtgttacgt gttcgcgcag gagcgcgggc tgttcgaccg gctgacgtcg
    18541 ttggtgcaga cgcaggacca gcagccgttc tacgtggcgg cggagcagaa gatctccgac
    18601 gcggcgcggg agtccgggtt ggcgcagcgg gcggaggaca acacccgcaa gatgctgacc
    18661 ggcatgttcg gcgcgctggg ctaccaggtc gagttcacga gcctggactg acctcggccg
    18721 ggagccaccc cgccagggcg tcgaggatca cgccgagccc gaacgggaac tcgtcggcga
    18781 agtcgttgcc cggtcgcagg acgtgctcgg tcgccatctc cacgaggtgc gggtactcgc
    18841 cctccccgaa gtgcgccatg atgtccgcgg tcacctcggt ggcggaatcg gggccgttga
    18901 aggggagcgc ggcctcttgg accgcgaacc cgtacacgta gctgtccagc agggcgtagg
    18961 cgtgggcggt catggcgacc gagaagcccg cgcggcgcag ggtgccgatg gtcgcgtcgt
    19021 ggtgtcgcag cgtcgccggg ccgggcgcct tgcgcgactc cagcaggccg atcgcccacg
    19081 ggtggcgctt gagcacgtca cgggcggagt ccgcccgctt gaccatctcg tgccgccagt
    19141 cgccgccggg cgtcggcagc tccatccggg cgaagaccag gtccacgatg ccgtcgagga
    19201 tctcgtcctt gttcttgacg tggtggtaga gggacatcgg cttgacgccg agcgcgtcgc
    19261 cgagggaccg catggtcagc cccgcgaggc cgcccgcgtc ggcgatggcg acggcggcgc
    19321 gcagcacgcg gtcccggctc agcggtgctc ctgccttcga catccgacct ccgtggtgac
    19381 ggttgcgcgg tggtgacggt cgcgtactta gtaaggtacc gtctgcctta ctaagtaagg
    19441 ccagcaccgc cggcgaaggg gaaccccatg tcaacgagag ccatcggccg ggccatgggg
    19501 gcgctgttcc tcctggcgtt cgtcgcgtac ggcaccggca ccgccctggt cggttcgggg
    19561 tcgggcgcgc gggtggccgc gggagccctg ctgatgctgg tgaactccgc cgtcgtggtc
    19621 ggcatcggcg tgctggcgtt cccggtgctg cgaccgcacg gcgagctgac cgcgcacgcg
    19681 tacctggtcg gccgggcggc ggaggcggcg ctgttggccg tcggcgtcgt gttcgtgctg
    19741 ctgccggcgt cggccggggt gggcgcggcg ggcaaccact acagctacca ggtggcgatg
    19801 atggccgtgg gcgccgtggg cgtgctgttc tgccgggtcc tgctgcgcgc ccgtctggtg
    19861 caccgcgcca tcgcggtgtg gggcgtggtc ggctacgccg tcttcctgct gggcgcggtc
    19921 ctcgaagtgc tcggctacgg cgtcggcgtg gcgctctccg tcccgggcgg cctgttcgag
    19981 gtcgcgctgg gggtcctgct gatcgccagg ggcttcgccc ggtccgaggt cgaccgggaa
    20041 ccggcgctgg cgggctagcg catcgtcgcg ccgcccgccc cggccagggc gaggacggcc
    20101 tcgtggtgcg cggaggggac ggggtgctgc gcgagccggt cgcgcggacc gatcaggtgg
    20161 accttccgcc gggccgcggg ttcccgctgc cgcagcgcca ccacccccgg gcgaggaggc
    20221 cggccgccgg cgcggtgagg aggatgccgc cgacgagcgc gagcacgtcc ccgtcggccc
    20281 gcgccggcag caggaccccg aagaacgcgg gcagcaccgc gaacgccgcc gccgtgccga
    20341 accccctgga ccaggggttg agccggacca cctcgacgaa ctcgccgtac ccgtgccgcc
    20401 cggcgacctc gacggcctcg gcccgggtgc ccgcccggac cggcgtgccg ccgcgtcgcc
    20461 ctcccccgtc acgggcccgc gatcacgtcg accgccaggg cgccggagga caccgggccc
    20521 cggtccggaa cggcgtatgc tgcccgacga tgaggcgcaa gctccggccg ccgctggacc
    20581 agcggcacgg cctcgacccg gcacggctgc ggttccccga cgacgggccg tggacgacgg
    20641 tccgcgacca cctggtcgac cggttgcccc gggtcgcgcc cgagcggatc gacctgatgc
    20701 tcgccgaggg ccgcgtgtac ggcctcgccg gcccgatcgc gccggacgcc ccgttcacgc
    20761 ccggcggcgc ggtgtggttc caccgcgacc tgcccgacga ggtggcggtg cccttcgaga
    20821 tccgggtcgt gcaccgcgac gacgccctcc tcgtggtcga caagccgcac ttcctggcca
    20881 cgatcccgcg cggcaagcac gtggtcgaga cggcgctcgt ccggctgcgc cgcgacctcg
    20941 ggctgccgca gctgagcccc gcgcaccggc tggaccgggt gaccgccggc ctggtcatgt
    21001 tcgtggtcga gccgaccctg cgcggcaagt accagaccct gttcgccgac cgcgcggtgc
    21061 gcaaggagta cgaggccatc gcgccgcacg accccgcgct gaccctgcct gcccgcgtga
    21121 gcagccgcat cgtgaaggtc
//
