LOCUS       NZ_CP064192            20906 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Saccharothrix sp. 6-C chromosome, complete genome.
ACCESSION   NZ_CP064192
VERSION     NZ_CP064192.1
KEYWORDS    RefSeq.
SOURCE      Saccharothrix sp. 6-C
  ORGANISM  Saccharothrix sp. 6-C
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharothrix.
REFERENCE   1  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Saccharothrix texasensis strain 6-C
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) College of Life Sciences, Chongqing
            University, University Town Road, Chongqing, Chongqing 401331, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 10:20:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,916
            Genes (coding)                    :: 7,819
            CDSs (with protein)               :: 7,819
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 78 of 97
            Pseudo Genes (internal stop)      :: 6 of 97
            Pseudo Genes (multiple problems)  :: 27 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:34:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4398088
            Orig. end                         :: 4418994
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064192.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20906
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="20"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20906
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20906
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10906](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10906
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(471..1028)
                     /locus_tag="IOD16_RS18330"
                     /old_locus_tag="IOD16_18235"
     CDS             complement(471..1028)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18235"
                     /product="hypothetical protein"
                     /protein_id="WP_201441014.1"
                     /transl_table=11
                     /translation="MGSNGLETALECVERGWSVVPGALWIDDTYVDPVTNADSEALALS
                     SPVLATLDPEEVRRLWPVLEEGVTRSTLAVLGTLMTAIVVEPERARLVIEFEAFRSAPT
                     PVVMLPIPMFGVMIESAVFVVSSSGGLDEKLVFPADGLLPLPPAVVEGYETRWLVSPVE
                     CDGLMSGPELARLLALETSNRR"
     gene            complement(1018..1353)
                     /locus_tag="IOD16_RS18335"
                     /old_locus_tag="IOD16_18240"
     CDS             complement(1018..1353)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18240"
                     /product="hypothetical protein"
                     /protein_id="WP_201441015.1"
                     /transl_table=11
                     /translation="MTLTLESDGDQAEGGETPVSLFDDPKIVGDVQELVNDQAPRVFAV
                     VQETFGPPEDLQIVAWGMTTKTGVEVVSVHGGTRMGLQSAENALIFYRAGGRAIPQIFW
                     VGGEGGE"
     gene            complement(1331..1624)
                     /locus_tag="IOD16_RS18340"
                     /old_locus_tag="IOD16_18245"
     CDS             complement(1331..1624)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18245"
                     /product="hypothetical protein"
                     /protein_id="WP_201441016.1"
                     /transl_table=11
                     /translation="MGQAEVIPSDWTAGQPVFSGSSEAVMFVVWSELASDLGGVVLFLV
                     WLVMPLLYLVAVGRRYVRQCQENAQAAVWARDEVRLIREEQREGSHDLDAGE"
     misc_feature    1660..1676
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            complement(1799..2971)
                     /locus_tag="IOD16_RS18345"
                     /old_locus_tag="IOD16_18250"
     CDS             complement(1799..2971)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="IOD16_RS18345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18250"
                     /product="protein kinase family protein"
                     /protein_id="WP_201441017.1"
                     /sec_met_domain="Pkinase (E-value: 3.7e-24, bitscore: 84.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVREDLVLSDLHDRYGATPADPAFLRLYSTTDSNLAPVFASFHQR
                     LNYLLDFMNQKKRVNGHYNADESRQLLDLIVELEEVQATLRRVGVEFWISPVYQLALDR
                     CKKFLTRSGGSSIPDDFGPIAVERYDQVFASVDEVVRPKPSQRQYPLQLVGEGSYAIVH
                     KYLDEERGVYIAVKRARKGLLPKDLKRFRAEYDLLRNLSFPYIVQAYAYDDLNNSYTME
                     YCDATLASFISRHNARLSFGVRKRIALQFLYGVNYLHFKGILHRDISRRNILVKQYEFP
                     AVMVKLSDFGLHKEIGSGLTATGSSMKGTIIDPTLDHFKDFDTLAEIYAIGSVLSFIFS
                     GRERLGVCTGRIGEIVDRCTSIRRDARYSSVVDIIADVETLPMDDETTSA"
     misc_feature    complement(3024..3039)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.95"
                     /tool="antismash"
     misc_feature    complement(3080..3097)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     gene            complement(3099..3911)
                     /locus_tag="IOD16_RS18350"
                     /old_locus_tag="IOD16_18255"
     CDS             complement(3099..3911)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18255"
                     /product="hypothetical protein"
                     /protein_id="WP_201441018.1"
                     /transl_table=11
                     /translation="MPQDEHVQIEAREWRSLALPQPLSFAPPYASRSTNPDGYRYWWQL
                     IRFVFDLPDPNKFPPLEGFTPDELRVLERYVDTCYELSESTVLSSKGGIRVSFKDGVEQ
                     VSADLPSKEALRGTVVLFRQLASTEEPASYNKTRKIIGRRVNFQADSRRDERIEWQQRW
                     NRAHGLLSASLLTAMADRKVIERMGGASSLPVPGEDVKPQEILSLFQYGDLIHWARNAE
                     EMQALMKDEFLIKWRTVQFIEVVIQLSHFYMGYSLLVSTAIKRSAGSS"
     misc_feature    complement(3980..3998)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.75"
                     /tool="antismash"
     misc_feature    complement(4004..4019)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(4043..4063)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.6"
                     /tool="antismash"
     gene            complement(4383..5897)
                     /locus_tag="IOD16_RS18355"
                     /old_locus_tag="IOD16_18260"
     CDS             complement(4383..5897)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /locus_tag="IOD16_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18260"
                     /product="recombinase family protein"
                     /protein_id="WP_201441019.1"
                     /transl_table=11
                     /translation="MSVSALSRPTTLAEWIAATVPPGIPTMDATPVGSLRFLFYGRAST
                     HEHQDPRTSRAWQLDVSRRLTGGHGRIVGEYVEVGCSRQVPWHLRPRAAAMLRYIATNA
                     ARVDAVVVGEYERAFLDTSQVRELRAVLERYGVQLWLPEAEGPVDFGNPAHEALLTLLA
                     KRSLTEVLRSRHRVVTAMRMQTVEQGRYLGGRPPYGYRLVDASPHPNRALARRGVRQQR
                     LVPNPATALVVKLIFTLRLAGHSAAGIARHLNEQAVPTPSSADAERDRRWVDAGWSRTR
                     PEGAPGNLYLREDHLLSRIAAHLTAVGIADNPGPEHTARLVDELGLVFRCDTAGVALLD
                     RGSTGPARAPRRRLAPQPVHSSPGTEHPGKAGEQLLLTVSCAPASEADQPDAPRGQIDA
                     PAHRTRPTRQPLRRRIGPAAPQGRRRQTAFHVALGTTRSRNASRAGGAEYRLPGQHGGD
                     RGRQVVGRAGRRPLLLPSHRQTSYEQRPSGRVEAGSGNTMPHETPS"
     misc_feature    complement(5181..5183)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6172..8328)
                     /locus_tag="IOD16_RS18360"
                     /old_locus_tag="IOD16_18265"
     CDS             complement(6172..8328)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088219.1"
                     /locus_tag="IOD16_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18265"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_236595079.1"
                     /transl_table=11
                     /translation="MHGNLNLHPPPPRPAPVIPRQLPAAPGLFTGRTAELARLDRALTH
                     AATPQEPGTDTREPTTAAPTTGPAGAGTTVLVSAIGGAGGIGKTWLALAWAYRHLERFP
                     DGQLFVDLHGFSPTGESVAPAVAVRGFLDALGVDPNRIPADLDAQAALYRSLVAGRRML
                     IVLDNAATAEQVVPLLPGSPSCTVLVTGRHRLASLIDRHGARHLPLDVLTYEEARGLLA
                     ARLGADRVAAEPEAVDELIGLCGGHPLALSIIARTAGPHPDVALAETAAELRDLGLEAL
                     DHDTDPAASLPTVLSRSLRHLTDTQRTVFALLGITPGPDTTPPATAALTGLPNRTARRT
                     LSGLENASLLERRPGGRYAMHDLVRAYAADTAHTILPEHVREAALTRVVDFHLHTAHTA
                     DRLLDPHCTPLSPEPPAPGVHPHPLPDTAAALAWLQAEHATLLATQRTAATLGHHHTIW
                     HLAWNLTTFHNRRGHRHDAVTTWRAALAAADHLPDPTTRGRTHRLLGNACSVLGLHEQA
                     TTHLEQALDLAVRHHDPTGQAHTHQVLALAWEQRRDDRQALEHAHRALALIRALDQPVW
                     EAESLNAVGWYAARLGRFDTAREHCQAALTLHRHHHDPDGEAATLDSLGYIAHHTGDHH
                     QALDHYHHALTLFRGIGYAYQVADNLDSVGHPHAALGQFDLARTVWREALELYREQGRD
                     TDAERVQQQLDELDHFTSANPDSG"
     gene            complement(8466..9443)
                     /locus_tag="IOD16_RS18365"
                     /old_locus_tag="IOD16_18270"
     CDS             complement(8466..9443)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="IOD16_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18270"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_201441021.1"
                     /transl_table=11
                     /translation="MEIRILGNVEIHSDDDVITLTRSAERCLLGLLAVEVGRPVPVTTL
                     LDRIWVEEGRSEPKPETLIRYVGYIRDAMERAGGDGIWLRHEPGANAYLLDVDPGTVDY
                     HRFLRETRAAGEHRDLDRLHDALALWRGTPLEDVRRRWVDTFRHHAHAHRRTALATLWE
                     LLLEQGRHHEIPPQLGPLEADIVHDERLLLLGAEALAHSGRHVDITAWADHIATRMRDL
                     SGGTGLSTLTQSRLHHLVTHPPGPTTPTPHNSTPTGTNGESSDLGTGDIGSSHHEGVSG
                     AGGRSTTIHGGVNGAAWGITIGAATGDHLTISAPPQTGEPDNPR"
     misc_feature    9900..9914
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     gene            10001..10906
                     /locus_tag="IOD16_RS18370"
                     /old_locus_tag="IOD16_18275"
     CDS             10001..10906
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003082534.1"
                     /locus_tag="IOD16_RS18370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18275"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_236595080.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 5.1e-20,
                     bitscore: 70.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 2.3e-37, bitscore: 127.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYEHRPVRLGEDRVQIGGWVHGVGAIIPDPDGWVWALLTLLDGT
                     RTVDQVVADLVHHHPRHPAADIADAIGELWQAGYLENAAAPEPPGLSLAERERYGRSRA
                     LWRWTDLAPRTTTWDAQLALRQARVTVIGVGGAGSTAALALTASGVGTIHLVEPDTVEL
                     SNLNRQILYTEHDLGRPKIDAAIGRLRAHNREVTVTGEQLLVDGPGVLRRLSTGCDVLL
                     LAADIPQEIRSWTNRACLDTGTAWVHGGYHGPRVNVGLFRPGSGPCYDCARTATAEHLA
                     AEPPITPWPPLGQTGARHLV"
     aSDomain        10004..10261
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IOD16_RS18370_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.80E-22"
                     /identifier="RREFam017.1"
                     /label="IOD16_RS18370"
                     /locus_tag="IOD16_RS18370"
                     /protein_end="87"
                     /protein_start="1"
                     /score="70.3"
                     /tool="antismash"
                     /translation="KYEHRPVRLGEDRVQIGGWVHGVGAIIPDPDGWVWALLTLLDGTR
                     TVDQVVADLVHHHPRHPAADIADAIGELWQAGYLENAAAPE"
     gene            <11019..12388
                     /locus_tag="IOD16_RS18380"
                     /old_locus_tag="IOD16_18285"
                     /pseudo=""
     CDS             <11019..12388
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612118.1"
                     /locus_tag="IOD16_RS18380"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="IOD16_18285"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="PSRRTFTTEYKLALVAEYENAPNGEKGAILRREGLYSSHVIEWTR
                     ARDAGRLGGAAAESTASATPARRSAEQVELEKLRRQNEKLASDLVRTRMALDIMGKAHA
                     LLRELSVSTDEGRPPRT"
     gene            12478..12648
                     /locus_tag="IOD16_RS18385"
                     /old_locus_tag="IOD16_18290"
     CDS             12478..12648
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18290"
                     /product="hypothetical protein"
                     /protein_id="WP_236595081.1"
                     /transl_table=11
                     /translation="MAGNLAAHAVMSLITGAPALPVNREYGINLVTLQDTFALGIQSAR
                     PDCPACGPFAA"
     gene            complement(12689..13105)
                     /locus_tag="IOD16_RS18390"
                     /old_locus_tag="IOD16_18295"
     CDS             complement(12689..13105)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18295"
                     /product="hypothetical protein"
                     /protein_id="WP_201441024.1"
                     /transl_table=11
                     /translation="MVVEVRDLRQTSAALGRFEDAVEYAELEVVLRLRVGKPLGVAYAL
                     HDVAVARQGLGEHDTVVGLCEQSVAAYGEHGGAEAERAKALETLATSLIHLGRIREAVE
                     RLREAAAIMAEAGDPRAGQVLRRAEALVDPDDRG"
     misc_feature    complement(13124..13137)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            13124..13672
                     /locus_tag="IOD16_RS18395"
                     /old_locus_tag="IOD16_18300"
     CDS             13124..13672
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1229: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024751.4"
                     /locus_tag="IOD16_RS18395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18300"
                     /product="IS630 family transposase"
                     /protein_id="WP_236595082.1"
                     /transl_table=11
                     /translation="MICVDEFGPLNLQPRKGKAWRPTGSPLRLRATYNRHHGVMHMLAA
                     LDLTTGKIHYRIRRRKRHAEFLDLLESLRARWPGQKLYIVADNFSPHRHPDVRAWAADH
                     DVELVFLPTYGSWLNWIEAEFTALRYFALNGTDHRTHAEQNTAIAAYIRWRNARARPKT
                     GFATDSPIRTWTHYPIKVA"
     misc_feature    13208..13210
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<13698..13965)
                     /locus_tag="IOD16_RS18400"
                     /old_locus_tag="IOD16_18305"
                     /pseudo=""
     CDS             complement(<13698..13965)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890318.1"
                     /locus_tag="IOD16_RS18400"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="IOD16_18305"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLSYPAAIPLSNHTLVRLGDLIRAERVRRRSRWRRLGPGRQALLV
                     RPSAQRRHLCSSGRRIRSFLQHRLALRPGSGGPSRRPGRRPPRR"
     gene            complement(14094..14816)
                     /locus_tag="IOD16_RS18405"
                     /old_locus_tag="IOD16_18310"
     CDS             complement(14094..14816)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18310"
                     /product="hypothetical protein"
                     /protein_id="WP_201441025.1"
                     /transl_table=11
                     /translation="MEQATKIIFLIAFLFVGVFGAIVWLFQANVKHSTGSASGPEPATF
                     EVCQATSPPMVTEVGKATLFEVAMHLDRAECVASDDDSHRRLTAATNMIKVEMPGSGFD
                     GRIELLGSDTQPLDEKRRKAIWRWVLKADRPGDYELPIVITFQDPEGGLWLQDMQSKLR
                     FRVDGHIGYRISRAAQWLRDFVNTTEVIIGGTAAIVGTFGAAAWRRGVESSRNVGNARR
                     NSRLGKGVGYGKVIRRRK"
     misc_feature    complement(14139..14141)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14556..14558)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15165..16157)
                     /locus_tag="IOD16_RS18410"
                     /old_locus_tag="IOD16_18315"
     CDS             complement(15165..16157)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033545.0"
                     /locus_tag="IOD16_RS18410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18315"
                     /product="IS630 family transposase"
                     /protein_id="WP_201441026.1"
                     /transl_table=11
                     /translation="MLRLRVVAALESGVVAGYRQAAEVFGVSERSVGSWWRAYRRDGRG
                     GLATRTGRPGPVELIGAEDRGTLFAAMADYTPEELLIGGPLWTRQAVVVLIRLVVGVDM
                     TEQGVGLWLRRHGFTPQRPARRAYEQQPAAVRAWLDEEYPAIEARAKAEGAAIAWVDQC
                     GLRSDAAPPGRSWAPKGRTPIVRVTGKRLRVNVMSAVASRGALWFTVFTERFTAAVFTA
                     FLDCVARQAGRKVHVIVDRHPVHRSKVVRTWLEDNADRVELHLMPGYSPELNPDELLNA
                     DLKRNVNASRAHNIDRLAHETRRFLRRRQRQPHIVHGYFQAPHVRYAAM"
     misc_feature    16718..16735
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    16927..16942
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.03"
                     /tool="antismash"
     gene            complement(16988..17317)
                     /locus_tag="IOD16_RS18415"
                     /old_locus_tag="IOD16_18320"
     CDS             complement(16988..17317)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18320"
                     /product="hypothetical protein"
                     /protein_id="WP_201441027.1"
                     /transl_table=11
                     /translation="MANQAALDPASRQSWAKRYQCNFSPHLFIGGQIQPMYGSAGQISQ
                     IAQIAVYSLTAIRERSAINSYRLAERIRELVPVSTLPIWSPTSDAFASSRNVGSVGVLE
                     ELGGR"
     gene            17472..17639
                     /locus_tag="IOD16_RS18420"
                     /old_locus_tag="IOD16_18325"
     CDS             17472..17639
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18325"
                     /product="hypothetical protein"
                     /protein_id="WP_201441028.1"
                     /transl_table=11
                     /translation="MPGRTEDLLFLLEYRPGPHRYVKPGLIAVHQATEALSAPAAAADD
                     GPAQPPPTSR"
     gene            complement(17763..17921)
                     /locus_tag="IOD16_RS18425"
                     /old_locus_tag="IOD16_18330"
     CDS             complement(17763..17921)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18330"
                     /product="hypothetical protein"
                     /protein_id="WP_201441029.1"
                     /transl_table=11
                     /translation="MAVSAALTSPCTTARLTPTPRAISRRAVPDAVERRREVVDETRAV
                     SRSRIGV"
     gene            complement(17946..18350)
                     /locus_tag="IOD16_RS18430"
                     /old_locus_tag="IOD16_18335"
     CDS             complement(17946..18350)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18335"
                     /product="hypothetical protein"
                     /protein_id="WP_201441030.1"
                     /transl_table=11
                     /translation="MTKKSTSVIAALGVTAAMVGTPSTTQAQSADHNTVAISCYAVADE
                     PWYRSPSVYATGHIYCNPWADAEITVKITANGALKGESSTGYTAPHITDTAVAQNWTGD
                     QKWCTLVSGTYYVNGRSYPVSATACESAGF"
     misc_feature    18381..18398
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.9"
                     /tool="antismash"
     gene            complement(18510..19580)
                     /locus_tag="IOD16_RS18435"
                     /old_locus_tag="IOD16_18340"
     CDS             complement(18510..19580)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630081.1"
                     /locus_tag="IOD16_RS18435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_18340"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_201441031.1"
                     /transl_table=11
                     /translation="MRMAALLAMLAFLIPVTAAAAPVPSSTTLVECANTMSDGEQLNAA
                     IRASLVGVEIVISGRCSIDSTIRLLGDRSYHGMSRTGTVIRQADGANLAALVASDSYLD
                     DTDFTGDPVTLRSLTLEGNREANPRAGDGLVLRSWASVVDPVPVLGANRHGIRVTNPSA
                     NGTLLGNTQVNGRISACHVAESGGSGIRVEDPGNAVTDWQLTDNWIASAGAAGISLDNT
                     AGWYVERNHVYDVAAGAIAAERLFGSSVSDNCIEDFAGFGIRASAQGEAASTVAHNRVV
                     GTSGEVSAFVSVRINYGAAAVAVVANTLRDSGTRIGLDYQAATGTTATIASTGNLVTGV
                     TTPRRVSSGVTVTTGI"
     misc_feature    19870..19884
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            complement(19882..20250)
                     /locus_tag="IOD16_RS18440"
                     /old_locus_tag="IOD16_18345"
     CDS             complement(19882..20250)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS18440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_18345"
                     /product="hypothetical protein"
                     /protein_id="WP_201441032.1"
                     /transl_table=11
                     /translation="MPTALLAGAALALTTLTAPGAQAGEIDAAACSWTVSTPGKSGSYV
                     RSTATTAGCSGSSRWHAVLQWRNFLGGWTNLDEASWSGNTSVSLTYVCTPGETETYRGI
                     IDRSDGQSKISLTRTITC"
ORIGIN
        1 cgacctccgc cccgcagcga gcctgtggag gtgacgcaag ctgatcgtgc cgggttctcc
       61 agcctcccgc gcgaagacct cgacgtactc ggcgaactcc tccagcgtct gctgtcggtc
      121 ccaaatcttc tgctcaagca ccgtccgcgc cgtccgcatg accacctcct atcggctgat
      181 tctgcgctga caagccgttg atttcagtgt gtcacgacgc agcagtcacc cgtcccgagg
      241 cccgtcccac ccaaccaacc cgtcccgacc gacgggacac caagcgcatc agcactgacc
      301 agcgaaaaca cgccgtagtg acgtttggga cgggacacat caacccgtcc cagacacgcg
      361 aaacggccgt gtgcgacgcc atccgaatgg atggttcgca cacggccgtc ccgtcccaca
      421 ggtgccgggg gaggcgtccg gcaccccatg cccaaccgtc gaaggtgcgg tcaacgacgg
      481 ttggaagtct ccagcgccaa cagccgcgcc agctccggcc cgctcatcag gccgtcacac
      541 tcgaccggcg acaccagcca ccgcgtctcg tatccctcga ccacagccgg cggtagcggc
      601 aacaacccat ccgcggggaa gaccagcttc tcgtccaacc ctccggacga cgacacgacg
      661 aacactgccg actcgatcat cacgccgaac atcgggatcg gcagcatcac caccggcgtc
      721 ggcgcacttc tgaacgcctc gaactcgatc accagccgag ctcgctccgg ctccacgacg
      781 atcgcggtca tcagcgtccc gaggacagcc aacgtcgacc gcgtgacgcc ctcctccaac
      841 accggccaca gtcgccgaac ctcctccggg tccagcgtcg ccaacaccgg agacgacagg
      901 gcaagcgctt cggagtcggc gttcgtcacg ggatcgacgt aggtgtcatc gatccacaac
      961 gcacccggaa ccaccgacca tccacgctcg acgcactcca gcgcggtctc cagcccgtta
     1021 ctccccacct tcgcccccaa cccagaagat ctggggaatc gcacgcccac cggcccggta
     1081 gaagatcaac gcgttctccg ccgactgcaa acccatacgc gtcccgccat gaacgctgac
     1141 cacctccaca ccggtcttgg tggtcatccc ccacgccacg atctgcaagt cctccggagg
     1201 cccgaacgtc tcctggacca ccgcgaacac ccgcggagcc tggtcgttca ccaactcctg
     1261 cacgtcgccg acgatcttcg gatcatcgaa cagcgaaaca ggcgtctcgc caccctctgc
     1321 ctggtccccg tcactctcca gcgtcaaggt catgactgcc ttccctctgc tcctcacgga
     1381 tcagacgcac ctcatcccgc gcccaaaccg ccgcctgtgc gttctcctgg cactgccgca
     1441 cgtaccgcct accgacagcg acgaggtaga gcagaggcat cacgagccac accaggaaca
     1501 gcacgacgcc gccgagatca ctcgccaact cactccacac cacgaacatc accgcctcag
     1561 acgatccgct gaacacaggt tgaccggcgg tccagtcgga aggaatgacc tctgcctgcc
     1621 ccacaaagac atgggaggtc aagcacgact aaaagcagct tgtaacttca cgaccataaa
     1681 ggaccgtgat ggcaatcaac aacttgattt atgcccttgg cgaccaagac acgcttgccg
     1741 atcgcgattg acagttggca cgattaccgc aagatccacg cagcctacag tcaaccaact
     1801 acgcagaagt cgtctcatcg tccatcggca atgtttcgac atcagcgatt atatcgacca
     1861 ccgatgaata tcgagcatct cggcgaatgc ttgtacaccg atccacaatt tctccaatcc
     1921 gaccagtgca aacacccagc cgctcacgcc ccgagaagat gaaagaaagt accgaaccta
     1981 tcgcatatat ctcggcaagt gtgtcgaagt ccttaaagtg atcgagcgtt ggatcgatga
     2041 tcgtcccctt cattgacgac cccgttgccg ttaggcccga cccgatctct ttgtgtagcc
     2101 caaaatcaga cagcttgacc ataacggcag gaaattcgta ttgcttaacc agaatattgc
     2161 gtcgactaat atctcgatga agaatacctt tgaagtggag gtagttaacg ccatacagga
     2221 attgcagcgc aatccttttg cggaccccaa agctcaaacg ggcattgtgt ctcgatataa
     2281 acgaagccaa ggtggcatcg cagtactcca tagtatacga gttgttgagg tcgtcgtagg
     2341 catacgcctg cactatgtac ggaaaactaa gatttctaag caaatcatac tcagctcgaa
     2401 accgcttcaa atccttcggc agaagtccct tcctagcacg tttaaccgca atatagacac
     2461 cccgctcctc gtcgaggtac ttgtgtacga ttgcataaga cccctcacct acaagttgaa
     2521 ggggatactg ccgttgcgac ggttttggac gaaccacttc gtccacggag gcgaaaacct
     2581 ggtcgtagcg ctcgacggca atcggtccaa agtcgtcggg aatagaactg ccgccagacc
     2641 gcgtcaggaa cttcttacag cgatcaagcg cgagttggta gacgggcgaa atccagaatt
     2701 ctacgccaac tctacgcaga gtggcctgca cctcctccaa ttcaacgatg aggtcgagga
     2761 gttgcctgct ttcatcagcg ttataatgtc cgttcacgcg cttcttttgg ttcataaaat
     2821 ctagcaagta gttaaggcgt tgatggaagg atgcgaacac tggagcaaga ttggagtccg
     2881 ttgtcgaata cagacggaga aacgccgggt cggccggtgt ggcgccgtaa cggtcatgca
     2941 agtcgctcaa cacaagatct tcacgtacca cgatccagcc accttcccga atatccgaag
     3001 tgagagacag tcaactgcga cacgttaaca actatagacg aagagccccg atgtaacgat
     3061 ccgacacaga gcgcactgat atccactaag tgcgatactt acgacgaccc tgcagaacgt
     3121 ttgatagccg ttgacaccaa aagagaatac cccatataga agtgactcaa ttggattacg
     3181 acttctataa attgaacagt gcgccatttg atgaggaatt catccttcat caaggcctgc
     3241 atctcttcgg cgtttcgcgc ccagtggatc aaatctccgt actgaaaaag agacaaaatt
     3301 tcctgcggct tcacgtcttc ccctggaacg ggaagcgacg atgcaccccc catacgttca
     3361 atgacctttc gatcggccat tgctgtcaaa agcgatgcac tgagaaggcc atgagcacga
     3421 ttccatcgct gttgccactc aattcgctca tcgcgacggc tgtcagcttg aaaatttact
     3481 cgcctaccga taatctttcg cgttttattg taacttgcgg gttcctctgt gcttgcgagt
     3541 tgtcggaaga gcacaactgt cccccgcaga gcttctttac tcggcagatc cgcacttacc
     3601 tgctcgactc cgtccttaaa agagacacgg atacctcctt tactgctcaa cacagtggac
     3661 tctgacaact cgtaacatgt atcaacatag cgttcaagca cccgaagctc atcaggcgta
     3721 aaaccctcaa ggggaggaaa tttattcgga tcgggcaagt caaatacaaa acgaattagt
     3781 tgccaccaat accggtagcc gtcgggattc gtacttctcg atgcgtaggg aggagcaaaa
     3841 ctcaagggct gaggaagggc aaggctccgc cactcacgag cttctatctg gacgtgttca
     3901 tcttgaggca tggacagatt gtcgcacatg cccccctcga tgccagtgga gacacgccgc
     3961 accctaccga agggggaata ttggtgaaat atacggcacg ctcgatactt cctatcaatt
     4021 caaagctaac taattcagca agtaatagag ctctcgacca taagctcact agagcaacaa
     4081 agaggcgact ttccgaaagt agcgaacgcc aattaccata gaaatcgaag aaaggcctgc
     4141 actgctcacc tttacgcgat tcgccaccat atccgaatac tcagcctaaa gataggttag
     4201 tcgagcttgc atccatacgg acgtaaaaga agatacaaaa atcccgcctc gctcgcaaat
     4261 gtagctaacg cgagcggggc aggaatacgc ttaaatcatg cgatatcaac aagattgagg
     4321 cgtgtgaata gtgcgcaagt ccggcctcgg acacataatt tgccccgcga gatatctcca
     4381 ggtcagctgg gagtctcgtg gggcattgtg tttcccgacc ctgcttcgac cctacctgat
     4441 ggtcgctgct cgtaggatgt ctgccgatgc gagggcaaga gcagcgggcg gcgtccggct
     4501 cgtcccacga cctgtcgacc gcggtcaccg ccgtgctggc ccggcagccg gtactcagct
     4561 cccccggctc gggatgcgtt ccgcgaacgg gtggtgccga gggcgacgtg gaacgcggtc
     4621 tgccggcgcc gaccctgggg cgctgccggg ccgatccgtc gccggagagg ctggcgtgtg
     4681 gggcgggttc tgtgagccgg tgcatcgatc tgaccccttg gcgcatcggg ctgatccgct
     4741 tccgaggccg gcgcgcagct cacggtcagc aggagttgtt cgcctgcctt tccagggtgt
     4801 tcggtcccag ggctgctatg gactggctgc ggtgccaggc gcctgcgtgg tgcgcgcgct
     4861 ggcccggtgc tgccgcggtc gagcagggcg accccggcgg tgtcgcagcg gaagacgagt
     4921 ccgagctcgt cgaccagccg tgcggtgtgc tccgggccgg ggttgtcggc gatgcccacg
     4981 gcggtgaggt gtgcggcgat gcggctgagc aggtgatcct cgcgcaggta gaggttgccc
     5041 ggtgcgccct ccggtcgggt acgagaccaa cccgcatcga cccaacgtcg gtcgcgttcc
     5101 gcgtccgcgc tcgatggggt gggcacggcc tgctcgttga ggtggcgggc aatgcccgca
     5161 gcactgtgcc cggccagacg taaggtgaag atcagcttca cgacgagcgc ggtggccggg
     5221 ttcggcacga gtcgctgctg ccgcacaccg cgacgcgcca acgcccgatt cgggtgcggg
     5281 ctggcgtcga cgagccggta gccgtagggc ggcctgccgc cgaggtaacg tccctgttcg
     5341 acggtctgca tgcgcatggc ggtgacgacc cggtggcggg aacgcagcac ctctgtgagc
     5401 gagcgcttcg ccagcaatgt cagcagcgct tcgtgcgcgg ggttaccgaa gtccaccggc
     5461 ccctccgcct cgggcagcca cagctgcacc ccgtaccgct ccagcaccgc ccgcagctcc
     5521 cgcacctgac tggtgtcgag aaaggcgcgc tcgtactcgc cgaccaccac cgcgtcgacc
     5581 cgggccgcgt tcgtggcgat gtagcgcaac atcgccgcag cccgaggccg cagatgccac
     5641 ggcacctgac gggaacaccc gacctcgacg tactccccca cgattctgcc gtgcccgccg
     5701 gtgagccggc gggagacatc cagctgccac gcccgagagg tgcgcgggtc ctggtgctca
     5761 tgggtggaag cccggccgta gaacagaaac cgcagactgc cgacaggagt cgcatccatg
     5821 gtcgggatgc ccggcgggac cgtggcggcg atccactcgg caagcgtggt cggacgggac
     5881 agggcggaca ccgacatggc gcggtcctcg acatcggaac gggggttgga cgccggggtg
     5941 acgaggcgtc ttcgccatga tgacaaggaa ctccagatat acgcccgatc ggagcagccc
     6001 gagccgcctg tgcttgtctg aacagctgcg gcgtacgcgt atctgaccgt gcctggtggc
     6061 gtcgataccc acggcgagtc gctgctcgag agcgcggaac cgcgctgccg caggcttgac
     6121 gtcggcttca gtctctcgcg caccgacgcc gacctacccc aggtcgaccg ctcaaccgct
     6181 gtccgggttg gcgctggtga agtggtcgag ctcgtcgagc tgctgttgga cgcgttcggc
     6241 gtcggtgtcg cggccttgtt cccggtacag ctccagtgcc tcccgccaca ccgtgcgggc
     6301 taggtcgaac tgtccgagtg cagcgtgggg atggcccacg ctgtcgaggt tgtccgcgac
     6361 ctggtaggcg tagccgatgc cgcggaacag ggtgagggcg tggtggtagt ggtcgagggc
     6421 ctggtggtgg tcgccggtgt ggtgggcgat gtacccgagg ctgtccaggg tggccgcctc
     6481 gccgtcgggg tcgtggtggt gtcggtgcag ggtgagggcg gcctggcagt gctcgcgggc
     6541 ggtatcgaac cggcccaggc gcgcggcgta ccagcccacc gcgttgagcg actcggcttc
     6601 ccataccggc tggtcgaggg cgcgaatgag ggcgagggcg cggtgggcgt gctccagggc
     6661 ctgccggtcg tcccttcgct gttcccaggc gagcgcgagc acctggtggg tgtgggcctg
     6721 tccggtgggg tcgtggtggc gcacagccag gtccagggcc tgctccaggt gggtggtggc
     6781 ctgttcgtgc aggcccagca cggagcaggc gttgccgagg agtcggtggg tacggccgcg
     6841 ggtggtgggg tcgggcaggt ggtcggcggc ggccagtgcg gcccgccacg tggtgaccgc
     6901 gtcgtgccgg tgtccccgcc gattgtggaa ggtggtcagg ttccaggcca ggtgccagat
     6961 ggtgtggtgg tggccgaggg tggcggcggt gcgttgggtg gccagcaggg tggcgtgctc
     7021 ggcctgcagc caggccagcg ccgcggcggt gtcgggcagc gggtgcgggt ggacgccggg
     7081 cgcgggcggc tcgggcgaca ggggcgtgca gtgggggtcc aggaggcggt cggcggtgtg
     7141 ggcggtgtgc aggtggaagt ccaccacccg ggtcagagcc gcttcccgca cgtgctcggg
     7201 caggatggtg tgggcggtgt ccgcggcgta ggcgcggacc aggtcgtgca tggcgtaccg
     7261 gccaccgggc cgccgttcca gcagtgaggc gttctccagc ccgctcagcg tcctgcgggc
     7321 ggtgcggttg ggcagtccgg tgagggcggc ggtggcgggt ggggtggtgt cgggtccggg
     7381 ggtgatgccc agcagcgcga acacggtgcg ttgggtgtcg gtgaggtggc gcagggaccg
     7441 ggacagcaca gtgggcaggc tggcggccgg gtcggtgtcg tgatcgagcg cctccaggcc
     7501 gaggtcgcgc agttcggcgg cggtctcggc caacgcgacg tcggggtggg gcccggcggt
     7561 gcgcgcgatg atcgacaacg ccagcgggtg gcccccgcac agcccgatca gctcgtccac
     7621 ggcctcgggt tcggcggcga cgcggtcggc gcccaggcgg gcggccagca ggccgcgggc
     7681 ctcctcgtag gtgaggacgt cgaggggcag gtggcgggct ccgtgccggt cgatcagcga
     7741 ggccagccgg tgacggccgg tgaccagcac cgtgcaggac ggcgagccgg gtagcagcgg
     7801 cacgacctgc tcggcggtgg cggcgttgtc cagcacgatg agcatccgcc gcccggccac
     7861 caggctgcgg tacagcgctg cctgggcgtc gaggtcggcg gggatgcggt tcgggtcgac
     7921 gcccagggcg tcgaggaagc cgcgcaccgc caccgccggc gccaccgact caccggtggg
     7981 actgaagccg tgcaggtcca cgaacagctg cccgtcggga aatcgctcca ggtgccggta
     8041 tgcccatgcc agagcgagcc aggtcttgcc gatgcctccg gcaccgccga tcgccgagac
     8101 cagcactgtc gtccccgcac ctgccgggcc ggtagtgggg gctgcggtgg tcggttcccg
     8161 cgtgtcggtg cctggttcct gtggtgtggc ggcgtgggtc agggcgcggt ccaaccgggc
     8221 gagttccgcg gtccggccgg tgaacagtcc cggtgcggcg ggcagctgcc gcgggatgac
     8281 cggcgcgggt cgcggtggtg gcgggtgcag gttcaggttg ccgtgcacca caccgaccgc
     8341 ggcaccgtga tcggtggcga cgaggtcacc gtggatgctc gttgtcgccg cggtgccggc
     8401 ggccggggtg gtgtcggggt gaggcgggtc ggccgccgac gcggtgtgcc cgtggtccgc
     8461 gtcggctagc gagggttgtc cggttctccc gtctggggcg gtgcgctgat ggtgaggtgg
     8521 tcgccggtag cggcaccgat ggtgatgccc catgccgcgc cgttgacgcc accgtgaata
     8581 gtcgtactac gaccaccggc cccgctgaca ccctcgtggt ggctggagcc tatgtccccg
     8641 gtgccgaggt cgctggattc gccgttggtg cctgtgggtg tgctgttgtg cggggttggt
     8701 gtggtcgggc ctggcgggtg ggtgacgagg tgatgcaggc gggactgggt aagagtcgag
     8761 agcccggtgc cgccgctgag gtcgcgcatg cgggtggcga tgtggtcggc ccaggcggtg
     8821 atgtcgacgt gtcggccgct gtgagccagt gcctcggcgc ccaggagcag aagccgttcg
     8881 tcgtggacga tgtcggcttc cagcgggccg agctggggtg ggatctcgtg gtgtcgacct
     8941 tgttcgagca gcagttccca gagcgtggcc agggcggtgc ggcggtgtgc gtgggcgtgg
     9001 tggcggaagg tgtccaccca gcgtcggcgc acgtcctcca gcggcgtccc acgccacaac
     9061 gcgagggcgt cgtggaggcg gtcaaggtcg cggtgttcgc ccgcggcacg ggtttcccgc
     9121 aggaagcggt ggtagtcgac agtgccggga tcgacgtcga gaaggtaggc gttggcaccg
     9181 ggctcgtggc gtagccagat gccgtctccc cccgctcgtt ccatggcgtc gcgaatgtag
     9241 ccgacgtagc ggatcaaggt ttccggtttg ggttcgctgc gcccttcctc gacccagatc
     9301 cggtcgagca gcgtggtgac cgggacaggt cggccgacct cgacggccag caggcccaac
     9361 agacaccgct ccgccgacct ggtcaacgtg atgacgtcgt cgtcgctgtg gatctcgacg
     9421 ttgcccagta tccggatctc cacccgtccc cccggctgta gcccttgctg acgagcgcag
     9481 tctggcgaga tccgccccgt cgtccagccg caataacagt gctgcactcg tccgtaacgc
     9541 cagtccaccc ggatggggca ggtgtcgtcg accgtatgtg gcggttttgg gcgtcgggtc
     9601 atccggttgg tgtccgacaa ctgcggacac cgcagcggac aagattccca cccgattggg
     9661 gtagcgatgt cggccgcggt gtcgaggacg ccgtccgggg atctgtcgcg tgccgcaacc
     9721 gacgctgttt ccagccccac aagagggaag cggggcggaa cggaaaccga cgtcatgagg
     9781 acggaatgga ctggacacgg gttcacgcac caccaccgga cgaacagcag ccaccgtggt
     9841 cgtgtctggc gttcaccgcc cagcgccgcc tcggagcacg cggcgagggg gtgaggacat
     9901 gatcatcaca ttcatcccga tcgagcggga gaagaccttc agcaagccca agaacgacaa
     9961 caactagaag acgggaggga gtgtcatgtt tcgtccgtgt gtgaagtacg agcaccggcc
    10021 ggtccgcctc ggcgaggacc gggtgcaaat cggtggctgg gtccacggtg tgggcgcgat
    10081 catcccggac ccggacggct gggtgtgggc gttgctgacg ctcctggacg gcacccgcac
    10141 ggtggaccag gtggtcgccg acctggtcca ccaccacccc cgacaccctg ccgccgatat
    10201 cgccgacgcc atcggtgagc tgtggcaggc cggttacctg gagaacgccg ccgcaccgga
    10261 gccgcccggc ctaagcttgg ccgagcggga gcggtacggg cgcagccggg cgttgtggcg
    10321 gtggacggac ctcgccccgc gcacgacgac gtgggacgcg cagctggcgt tgcggcaggc
    10381 acgcgtcacc gtgatcgggg tcggcggtgc gggcagcacc gcggcgctgg cgctgaccgc
    10441 ctccggggtc ggcaccatcc acctggtcga gcccgacacg gtggagttgt ccaacctcaa
    10501 ccgccagatc ctctacaccg agcacgacct cgggcgcccc aagatcgacg ccgccatcgg
    10561 gcgcctgcgg gcacacaacc gcgaggtcac cgtgaccggt gagcaactgc tcgtcgacgg
    10621 tcccggcgtc ctgcgccggc tgtcgacagg gtgtgatgtg ctgctgctgg ccgccgacat
    10681 cccgcaggag atccggtcgt ggaccaaccg ggcgtgcctg gacaccggca ccgcgtgggt
    10741 ccacggcggc taccacggcc ccagggtcaa cgtcggcctg ttccgacccg gttccggccc
    10801 gtgctacgac tgcgcacgca ccgccaccgc ggaacacctg gccgccgaac caccgatcac
    10861 cccgtggccc cctcttggtc agactggtgc gagacacctc gtgtgatcga ggttcgtgat
    10921 caagggcggg atcggagatt cttgtgctcg tgtccacccc atccgacaag cagtcccggc
    10981 gttcctccgg cgcgacaccc accgatccgg ccgcgcgtcc gtcccggcgg acgttcacca
    11041 ccgagtacaa gctcgctttg gtcgcggagt acgagaatgc cccgaacggg gagaagggcg
    11101 cgatcctgcg ccgcgagggc ctgtactcct cgcacgtcat cgagtggacc cgggctcgag
    11161 acgcgggccg gttgggcggt gcggcggcgg aatcgacggc ctcggcgaca ccggcgcgca
    11221 ggtcggccga gcaggtcgag ctggagaagc tgcgccggca gaacgagaag ttggcctccg
    11281 acctggtcag gacccggatg gcgctggaca tcatgggaaa agctcacgcg ctcttgcggg
    11341 aactctccgt gagcacggac gagggcaggc cgcccaggac gtgacggcgg ccgcgttcgc
    11401 cgagctgcgc gccgccgacg tcccggtaac cacgtcgtgc gcgctgaccg gcaggtcccg
    11461 ggccacgcac taccgccacg ccgggatgac gggcccgccg tccggccccc ggccgcgacg
    11521 tcgtccgccg ccgcacgccc tggacgcagc cgaacgcacc gaggtgttgg aggtgttgac
    11581 cagccctgtc taccgggacc tggcgatccc gcaggtgtgg gcacgcgagt tggacgaggg
    11641 ccgttaccgg tgctcgatct ccacgatgta ccggatcgcc cgcgccgccg ggcaggtccg
    11701 cgaacgccgc cgcaccgcca cccacccgcc ccggacacgc ccggaactgc tcgcccgtgg
    11761 tccgagccag gtgtggtcgt gggacatcac cgcgttgaaa gggccggtga aaggcatctg
    11821 gtaccgctgt tacgtcgtgc tggacatctt ctcccggtac gtcaccgggt ggctggtcgc
    11881 cgccgcggag gacgcggtcg tggccaggga cttcctcgcc gacgccgtcg cccgcaacgg
    11941 caccgcgcca cacacggtcc acgccgaccg cggcggcgcc atggtctcca aaccggtctc
    12001 cgcgctcctg gtcgacctcg gcgtgctccg ctcgcattcc cgtccccgcg tctcgaacga
    12061 caacccctat tccgaagccc agttcaagac gatgaagtac gtgcccgact tccccgaacg
    12121 gttcggctcc ctggccgacg cccgcgcgtt ctgcgaggag ttcttcctcg cctacaacca
    12181 cgaacaccgt cactccggca tcggcatgca cacccccgcg tccgtccact tcggaaccgc
    12241 agaacagatc cgcgaccaac gccaggccac tctcgaccgc gcccacaccc gacacccaca
    12301 acgcttcgca caccgacccc gaccaccccg actgcccgag acagcctgga tcaaccagcc
    12361 tgtcgagcaa ccgcaaccga ccccgtaaac acaacctgtc tcatctgaat tgacaactac
    12421 cggcccgccc aggccgatac ggaaggagtg cacgcgacca acgcggtgac ggccgggatg
    12481 gcgggcaacc tggcggcgca cgcggtgatg agcctgatca ccggtgcccc ggcgttgccg
    12541 gtcaaccgcg agtacggcat caacctggtc accctccagg acaccttcgc cctcggtatc
    12601 cagtcggccc ggccagattg ccccgcctgc gggccgttcg ctgcctgagc cggtgggtcg
    12661 cgccccgtca cggggtgcga cccgccggct atccgcgatc gtcgggatcc accagtgctt
    12721 cggcccgccg cagtacctgt ccggcgcgcg gatcaccggc ctcggccatg atcgcggcag
    12781 cctcccgcag acgctccacc gcctctcgta tccggccgag gtggatcagc gaggtcgcga
    12841 gggtctccaa ggctttggca cgttcggctt ccgcgccgcc gtgctcgcca taggcagcca
    12901 cggactgctc gcacaacccg accacggtgt cgtgctcgcc caacccctgc cgagcgacag
    12961 ccacgtcgtg cagggcgtac gccaccccga gcggcttacc cacccgaagc cgcaacacca
    13021 cctccagttc ggcgtactcc accgcatcct cgaaccgccc cagcgcggcg ctggtctgac
    13081 gtagatcccg gacctctacg accacccgcc cgacgacggc cgggtgatct gcgtcgacga
    13141 gttcgggccg ctcaacctcc agccccgcaa gggcaaggcc tggcggccga ccggctcacc
    13201 actgcgatta cgggccacct acaaccgcca ccacggcgtc atgcacatgc tcgccgcact
    13261 cgacctgacc accgggaaga tccactaccg catccggcgc cgcaaacgcc acgccgagtt
    13321 cctcgacctc ctcgagtccc tgcgcgccag gtggccggga cagaagctct acatcgtggc
    13381 cgacaacttc tcgccgcacc gccaccccga cgtccgcgcc tgggccgccg accatgacgt
    13441 cgagctagtg ttcctgccga cctacggttc ctggctgaac tggatcgagg ccgagttcac
    13501 cgccctgcgc tacttcgccc tcaacggcac cgaccaccgc acccacgccg agcagaacac
    13561 cgccatcgcg gcctacatcc gctggcgcaa cgccagagcc cgacccaaga ccggcttcgc
    13621 caccgactca cccatccgca cctggaccca ttacccgatc aaggttgctt gacgcagcac
    13681 taggcagcgc gtcgaccggc ggcgtggagg tcgtcggcca gggcggcgag aaggtccacc
    13741 gcttcccgga cgtagcgcca ggcggtgctg caggaaactt cgaatccggc ggccagacga
    13801 gcacaggtgt cgccgttgcg cagatgggcg aaccagcagc gcctgacggc cgggacccag
    13861 gcgccgccac cgggatcgtc gtcgcacacg ctcggcacgg atcaggtcgc ccaggcggac
    13921 gagggtgtgg ttggacagcg gaatcgcggc agggtaagac agcacggcga ggctcccggt
    13981 cggggcatcg gatcttggtc gactgctgtc ttaccgagag cctcgcccac cccgctccct
    14041 actactcagc ctgcgctgtg acctgcgacg tcacgatgaa aatggctcaa tgatcacttt
    14101 cgccgccgta tcacctttcc gtagccgacc cccttcccta aacgcgaatt ccttcgagca
    14161 ttaccgacgt tccttgaact ttccacacct cgcctccagg cagccgcacc gaaggtgccg
    14221 acaatcgcag ccgtgccacc tattatcact tccgtggtgt tgacaaaatc gcgcagccat
    14281 tgcgctgcac gtgagatacg gtagccgata tgtccatcaa cccgaaaccg caacttgctc
    14341 tgcatatcct gcagccagag ccctccctcg ggatcctgga aggtgattac gatgggtagc
    14401 tcgtaatctc caggccgatc ggcttttagt acccacctcc aaatggcctt tctacgcttc
    14461 tcgtccaagg gttgagtatc cgatcccaac aattcgatac gaccgtcgaa tcctgatcca
    14521 ggcatctcaa ctttgatcat gttggtggcc gccgttaaac gcctgtggga atcgtcatct
    14581 gacgcgacgc actcggccct gtccagatgc atcgccactt cgaatagcgt cgccttccca
    14641 acctccgtca ccatgggcgg cgaggtcgcc tgacaaacct cgaacgtcgc cggctcgggt
    14701 ccgctcgcac tcccggtaga gtgcttgacg ttagcctgaa atagccagac gatcgctccg
    14761 aaaacaccga cgaaaaggaa cgcgatcaga aaaataatct tcgtcgcctg ttccatggct
    14821 ctgaacctac ggagaatcac tctagatgcg ctgaacgatg aaactgacaa caagaagaga
    14881 ccaacgatga gcaaagttac aaccagcacg gcagtgaagt ccacatccat ctgcaaccag
    14941 ccttcggcac gtgacatacc caatagttaa attctactta tgcccttgac tgcaaagcaa
    15001 tggggacccc tctaccggac tactacgcaa cggaaattct agttcgtgtg gaaatcagcg
    15061 tagggaacag cgtcaggtcc gctggcggtt caccaccgac gacgcacgcg tcaaatttcg
    15121 ccacctatac cccgagagtt attgagccga aagtgttcgg ttgcctacat ggcggcgtag
    15181 cggacgtgcg gtgcctggaa gtagccgtgg acgatgtgcg gttggcgttg gcggcgtcgt
    15241 aggaagcgtc gggtctcgtg ggcgaggcgg tcgatgttgt gggcgcggga ggcgttgacg
    15301 ttgcgtttga ggtcggcgtt gagcagttcg tcggggttga gctcggggct gtagccgggc
    15361 atcaggtgca gctcgacccg gtcggcgttg tcctccagcc acgtgcggac gaccttgctg
    15421 cggtgcaccg ggtgccggtc gacgatgacg tgcaccttcc ggcctgcctg ccgggcgacg
    15481 cagtcgagga acgcggtgaa cacggccgcg gtgaagcgtt cggtgaagac ggtgaaccac
    15541 aacgcgccgc gtgaggcgac cgcggacatg acgttgaccc gtagccgttt cccggtcacc
    15601 cgcacgatcg gcgtgcggcc cttcggcgcc caggaccggc cgggcggcgc ggcatccgag
    15661 cgcaaaccgc attggtcgac ccacgcgatc gcggcaccct cggccttcgc ccgtgcctcg
    15721 atcgccggat actcctcgtc cagccacgcg cgcaccgcgg cgggctgctg ctcgtaggcg
    15781 cggcgggccg ggcgctgcgg ggtgaagccg tggcggcgca gccacaaccc cacaccctgt
    15841 tcggtcatgt cgaccccgac caccagccgg atcagcacga ccaccgcctg gcgggtccac
    15901 agcggcccgc cgatcagcaa ctcctccggc gtgtagtccg ccatcgccgc gaacagcgtg
    15961 ccccgatcct ccgcaccgat cagctcgacg gggccgggcc ttcccgtccg ggtcgccagg
    16021 ccgccacggc cgtcccgccg gtaggcacgc caccaactgc ccaccgagcg ctccgagacc
    16081 ccgaacacct ccgccgcctg ccgataaccc gcgaccaccc cggactccaa cgcggccacc
    16141 acccgcaacc gcagcacctc acgctccgca ggcgataacc gatgcgcacc ctcgacctcg
    16201 atcacaagcg atcaacctac cggaagacga tcactttcga ctcaatatct ccacgacgaa
    16261 cacgcgacag ttgaagacac gacctcacca atctggaagg ccctggtggt gatgcgtcga
    16321 gcttcgccgt cgcctgagtt cggccgctta ccaccatgtc catgtgatgc tggacttcat
    16381 agattccgcc gtgttcaagg ccacctcacc cggaattccg ccctcttcgg tgacgttcga
    16441 gatggacccc aagtagatac acgctgatcg gactaatcga tatcggccat tgagagaccc
    16501 tggcgcatcc ttgtgcctca aacttggcgc aacgccgtcg aaccttcaca aggggtggta
    16561 atctcgtgct cccagaaggg gggtcggttc gactgcggca tttcgctaca aacttgatat
    16621 tgctcggcgc gctcattcga catatgtcac gctttgtggc gtgcatataa catgaggtga
    16681 tgccagcgat ctatcacggg ggagatgttt gatgatatat cgaataaagt cgatagtgct
    16741 cgcattgctg agcgtcgggc ttctgatcgg ttcgacggga tctgcgcatg ccgagaactc
    16801 ggctactgca tcggctgcgg aaccgcaacg ggtcgtcgcg ctgaccggtg cggaggtcgg
    16861 ggtccagggc aactgcactg ggccgatctg cggcaagatc acgaactcaa gttcatccga
    16921 cgccagcatg caaatcatca actactggcc acccggtcct gctggcggac tctccctgag
    16981 gcccgggtca tcgtccaccc aattcttcaa ggacaccgac gctgcctaca ttccggctgg
    17041 atgcaaaggc gtcagaagtt gggctccaga ttgggagggt ggatactggt acaagttccc
    17101 ggatacgttc agcgagacgg tacgagttga ttgctgaccg ttcacggatg gcggtcagcg
    17161 agtacaccgc gatctgcgcg atctgcgaga tctgcccggc tgatccgtac atcggttgaa
    17221 tctgtccgcc aataaagagg tgtggcgaaa aattacattg ataacgtttc gcccaggact
    17281 gtcgacttgc cgggtcaagt gctgcttggt tggccatgcg acaaggtcgg acgtcctatc
    17341 cctgacgtct tgataaggca tgatgaaggg cgcagccgcc agcgactgcg cccttcatca
    17401 tggtcaccgc aagtccggca gatcggacga cgtgggcacc agcttgcggc gggcggcctt
    17461 gctggagctt tgtgccaggc cgcaccgagg acctgctgtt cctgttggag taccggcccg
    17521 gcccacaccg ctacgtcaag cccggcctga tcgcggttca ccaggccacc gaggcactgt
    17581 ccgcgcccgc cgccgcagcc gacgacggtc cggcgcagcc accacccaca agtcgatgac
    17641 cagcaccaac ccggctggac attgtttctg cacgcttgct actggaagac accccccagg
    17701 cgaccacaca ccgtcatctc accagcgaac ccgcgacagt tgaatacgcg acatcaccag
    17761 tctcaaacgc cgatccgcga ccgcgacacc gcccgcgtct cgtccacgac ctcccgccgc
    17821 cgctcgaccg cgtccggcac cgccctgcgc gagatcgccc gcggcgtcgg cgtcaacctc
    17881 gccgtggtgc acggcgaggt caacgccgcg gaaaccgcca tccggcagcc atcctaaccg
    17941 cgaagctaga atccggcgga ctcgcatgca gtagcggaaa cgggatagga tcggccgttg
    18001 acgtagtagg ttccggaaac caaagtgcac cacttctggt cgccggtcca gttctgggca
    18061 accgcggtgt cggtgatgtg cggagccgtg tagcccgtcg aactctcacc tttgagggcg
    18121 ccgttcgcgg taatcttcac tgtgatctcg gcgtcggccc acgggttgca gtagatgtga
    18181 cccgtggcgt agacacttgg acttctgtac cagggttcat ccgcgaccgc gtagcaagag
    18241 atcgccaccg tattgtgatc tgcggactgc gcttgggtcg tgctgggcgt gccgaccatg
    18301 gccgcggtga ctcccagcgc agctattacc gacgtcgact tcttggtcat tcctttgact
    18361 cccgccatga tgtttgccgg ttgatgttgc aatgttaaat tgccgggacc ccggaccggg
    18421 tcgaaagtat ctccggtctt ggttatcggc ggcgttatcc gaggctaggt gaatacgcgt
    18481 cttcgccagt cggcgacttg ggcttcgtgt cagatgcccg tggtgacggt gacgcccgag
    18541 gacacgcggc gtggtgtggt cacgccggtc accaggttgc cggtggaggc gatcgtcgcc
    18601 gtcgtgccgg tggcggcctg gtagtccaac ccgatcctgg tgccgctgtc gcggagggtg
    18661 ttggccacca cggccaccgc cgctgcgccg tagttgatgc gcaccgacac gaaggccgac
    18721 acctcgcccg aggtgcccac gacccggttg tgcgcgacgg tggaggctgc ctcgccctgc
    18781 gcggaggccc ggatgccgaa gccggcgaag tcctcgatgc agttgtcgga gacgctgctg
    18841 ccgaacaggc gctccgcggc gatggccccg gcggcgacgt cgtagacatg gttgcgctcg
    18901 acgtaccagc ccgcggtgtt gtccaggctg atcccggcgg cgcccgcgct ggcgatccag
    18961 ttgtcggtca actgccagtc ggtcaccgcg ttgcccgggt cctcgacccg gatgccactg
    19021 cccccggact ctgcgacgtg gcacgccgag atccggccgt tgacctgggt gttgcccaac
    19081 agggtcccgt tcgcggaggg attggtcacc cggatcccgt gccggttcgc cccgagcacc
    19141 ggcacgggat ccaccaccga cgcccacgac cgcagcacca acccgtcccc cgcgcgcggg
    19201 ttggcctccc gattcccctc caacgtcagc gaacgaaggg tcacggggtc accagtgaag
    19261 tccgtgtcat cgaggtagga gtcactggcc accaacgcgg ccaggttcgc cccgtccgcc
    19321 tgacggatca ccgtcccggt acgggacatc ccatgatagg aacggtcacc gagcagacgg
    19381 atcgtgctgt cgatcgaaca ccgccctgaa atcacgatct ccaccccgac aagactggcc
    19441 ctgatcgccg cgttgagctg ttcgccgtcc gacatcgtgt tcgcacactc caccagggtc
    19501 gtgctcgacg gcaccggtgc agcggccgcg gtcacgggaa tcaagaaagc caacattgcc
    19561 agaagggctg ccatgcgcat gatttctccg attggccaaa tcgatcgcac tggcagtgcg
    19621 ctagcaggat tgcgcgaacc gacctgtcga atatggaggg cagtaagcag gtcgagtggt
    19681 gtcgtaccgc gcttggcgcg gtacgacacc acgaccgcta atgaacgagg gtgtacggtg
    19741 acggtggacg cagtcgtcgg cagcttcagg tacgggaaac cggatagttt cgacgcgaca
    19801 tgcgggccgg ttgacgactg agaatgtcca cgaactcgtc aagatttcct tgagcgccac
    19861 caaatgatct ggacttggtg ttcagcaggt gattgttctg gtcaggctga tcttcgactg
    19921 gccgtctgag cggtcgatga tgcccctgta ggtctcggtc tcgcccggag tgcacacgta
    19981 ggtcagtgaa accgaggtgt tgccgctcca gctcgcctcg tccaggttgg tccagccccc
    20041 gaggaagttc cgccactgca gcaccgcgtg ccagcgtgag ctgcccgagc agcccgcagt
    20101 ggtcgcggtc gacctgacgt aggagccgga cttgccgggt gtactcaccg tccaactgca
    20161 ggcggcggca tcgatttctc ccgcttgcgc cccaggcgct gtcagggtgg tcaacgcaag
    20221 cgcggctccc gcgagaagag ccgtgggcat gatgtgacgt ctacgcatat ctccccttag
    20281 ttaagcgaac tgcacgtgcg aaaaacttct aacgttagtc gaacgctggc gcgcagactt
    20341 acgtgccgga tacggacgca gccgcaatcg cggccaactt ggcgatcttg gatgataccc
    20401 ctcctcgaca tgagctattc catcgatgtg ccgagcccgc attccggcca aacgtagatc
    20461 aggacgtgcg gttactgaca atgcctgact cggacttgcg cacctttgac tctcagtgcc
    20521 gagtgcttgc ctgttcgtgc ccgggtgcgc gatggagggt catgcgccgg tagtccgccg
    20581 gcggcatccc gaaggcggca cgaaaggcgc ggctgaaatg agccgcctcg ctgaatcccc
    20641 aacgggccgc aatggcgtgg atcgggtgcg tctgcaggcg gggatcggcg aggtcgcggt
    20701 ggcagcgttc gagccgttgc cggcgaatcc tggcggcgac cgtcgtgtct tggttctgga
    20761 acagtcggtg tagttgccgg agggagatgt ggtgggccga ggcgatcatg cccggcgaca
    20821 gggccgggtc gccgaggtgc tcgttgatga aggcgtgaat ccgggccagg agcgcctcgt
    20881 ggtggcgttc gggtggtagc gggttc
//
