LOCUS       NZ_CP064192            47296 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Saccharothrix sp. 6-C chromosome, complete genome.
ACCESSION   NZ_CP064192
VERSION     NZ_CP064192.1
KEYWORDS    RefSeq.
SOURCE      Saccharothrix sp. 6-C
  ORGANISM  Saccharothrix sp. 6-C
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharothrix.
REFERENCE   1  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Saccharothrix texasensis strain 6-C
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) College of Life Sciences, Chongqing
            University, University Town Road, Chongqing, Chongqing 401331, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 10:20:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,916
            Genes (coding)                    :: 7,819
            CDSs (with protein)               :: 7,819
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 78 of 97
            Pseudo Genes (internal stop)      :: 6 of 97
            Pseudo Genes (multiple problems)  :: 27 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:34:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3364894
            Orig. end                         :: 3412190
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064192.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..47296
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="15"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..47296
                     /SMILES="C([*])C(-O)(C)"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..47296
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:27296](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27296
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            390..1385
                     /locus_tag="IOD16_RS14520"
                     /old_locus_tag="IOD16_14525"
     CDS             390..1385
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Thioesterase (55-283). E-value: 5.4e-31.
                     Score: 100.7. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14520_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="IOD16_RS14520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14525"
                     /product="thioesterase domain-containing protein"
                     /protein_id="WP_123741240.1"
                     /sec_met_domain="Thioesterase (E-value: 8.5e-25, bitscore:
                     87.1, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 6.2e-05, bitscore: 21.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTREREDGPVDGSGVKALPAAEEFAWARQRRADIRRAGGVLDLV
                     LPLREGGAGPALFCAPPLVGASWCYLALLPHLAPEHPVHGLQLRGLRRPEPLPVDLAEA
                     ARDFADQIRLTQPHGPYHLFGWSIGGNTAHAIAEELERRGHEVGLLVIGDTVPGLPNSL
                     SVADDNLWLVCDFVLRELGYQPVVEPDDPDPVRRMLEVVRGRPGLGLHEWPDRQLLALP
                     HVIRNNLAAAQRHVPGRVRGPVLFLSATEDERSTESKVASWDDHVSTPVDVVEVDCLHE
                     HMLLPAPVARIGAAISARLGGPRVPGTNPKSPEPTAGALESFIATGEPRT"
     aSDomain        555..1238
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14520_Thioesterase.1"
                     /evalue="5.40E-31"
                     /label="IOD16_RS14520_Thioesterase.1"
                     /locus_tag="IOD16_RS14520"
                     /protein_end="283"
                     /protein_start="55"
                     /score="100.7"
                     /tool="antismash"
                     /translation="ALFCAPPLVGASWCYLALLPHLAPEHPVHGLQLRGLRRPEPLPVD
                     LAEAARDFADQIRLTQPHGPYHLFGWSIGGNTAHAIAEELERRGHEVGLLVIGDTVPGL
                     PNSLSVADDNLWLVCDFVLRELGYQPVVEPDDPDPVRRMLEVVRGRPGLGLHEWPDRQL
                     LALPHVIRNNLAAAQRHVPGRVRGPVLFLSATEDERSTESKVASWDDHVSTPVDVVEVD
                     CLHEHM"
     CDS_motif       735..809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14520_0001"
                     /evalue="8.50E-14"
                     /label="NRPS-te1"
                     /locus_tag="IOD16_RS14520"
                     /protein_end="140"
                     /protein_start="115"
                     /score="43.8"
                     /tool="antismash"
                     /translation="QPHGPYHLFGWSIGGNTAHAIAEEL"
     gene            1557..3203
                     /locus_tag="IOD16_RS14525"
                     /old_locus_tag="IOD16_14530"
     CDS             1557..3203
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (38-440). E-value: 8e-55.
                     Score: 178.0. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14525_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681766.1"
                     /locus_tag="IOD16_RS14525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14530"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_201440479.1"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-52, bitscore:
                     176.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGANLRTALAQDMRVGAGNVLPMLVEHGADPDTPRMTFDVDVDG
                     IPAWTPLSLRDLTERVAARADWFARKGIGRRDPVAVFVTSAADVFLNFFALNHLGAIPA
                     LMNGAMPIEVAAEFVRRLRGVGVLLDADHAALRDHELGVPVLGDAAETGTGDADQAPPP
                     YRHHDDDPVAITHSSGTTRMPTPVVHSHHSLFAAVRAVRLTEARPHGRVRELSVLPAAH
                     AAGIIVVNQALCNGYELLCLSAQGGPFERSGEVVLDAIERWRPTGVFGFAVTWAELARF
                     DLSKRDLGSVRNWSSTGDCAHEAHIRRLVAVGSHPVWTPDGVVDEPGSKFIDTLGSTEM
                     GHSAFAISHRPGSDRYDRCVGKPYPFAEVALLDVTTGEEVPVGQVGQCGLKSPTLAPGY
                     WNDSTATYRNRLNGYYLTGDLMYRDEEGYYYHLDRANDAVDLGGGEWLYTALSEERVLA
                     RCPDVRDCTVLASKQDDGAPVTDVLLVLHEGADPGLDRGEAVRAALGEAVARTVRRVDV
                     VPDEQLTVGPTGKVRKFLMRQRVLADAPHGR"
     aSDomain        1671..2876
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14525_AMP-binding.1"
                     /evalue="8.00E-55"
                     /label="IOD16_RS14525_AMP-binding.1"
                     /locus_tag="IOD16_RS14525"
                     /protein_end="440"
                     /protein_start="38"
                     /score="178.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FDVDVDGIPAWTPLSLRDLTERVAARADWFARKGIGRRDPVAVFV
                     TSAADVFLNFFALNHLGAIPALMNGAMPIEVAAEFVRRLRGVGVLLDADHAALRDHELG
                     VPVLGDAAETGTGDADQAPPPYRHHDDDPVAITHSSGTTRMPTPVVHSHHSLFAAVRAV
                     RLTEARPHGRVRELSVLPAAHAAGIIVVNQALCNGYELLCLSAQGGPFERSGEVVLDAI
                     ERWRPTGVFGFAVTWAELARFDLSKRDLGSVRNWSSTGDCAHEAHIRRLVAVGSHPVWT
                     PDGVVDEPGSKFIDTLGSTEMGHSAFAISHRPGSDRYDRCVGKPYPFAEVALLDVTTGE
                     EVPVGQVGQCGLKSPTLAPGYWNDSTATYRNRLNGYYLTGDLMYRDEEGYYYHLDRAND
                     AVD"
     CDS_motif       2697..2774
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14525_0001"
                     /evalue="1.40E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="IOD16_RS14525"
                     /protein_end="406"
                     /protein_start="380"
                     /score="14.3"
                     /tool="antismash"
                     /translation="PVGQVGQCGLKSPTLAPGYWNDSTAT"
     gene            3207..4889
                     /locus_tag="IOD16_RS14530"
                     /old_locus_tag="IOD16_14535"
     CDS             3207..4889
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (19-272). E-value:
                     1.2e-57. Score: 187.2. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14530_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (442-511). E-value: 9.2e-18. Score:
                     56.2. Matches aSDomain: nrpspksdomains_IOD16_RS14530_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="IOD16_RS14530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14535"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_201440480.1"
                     /sec_met_domain="Condensation (E-value: 1.9e-46, bitscore:
                     157.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.1e-11, bitscore:
                     41.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYPLSFEQEWALSRPAVLSHATWLDGPVDPAALRRAVDVVVARH
                     PVLRTHVTASGEQVVSETGRVVLEHVVLPGDVARAESVAAELAERPFDLSREPLTRAAV
                     IEVGAGRWLFALVAHRVVADGSTLAMLLADLSTVYREGLSELPSSWMDYGDYAVWQRER
                     LRGEELARQLAHWREVLRDAPAPVRLPAGRRAASLTAVVDPTAVRRLAAVAEGAGATLP
                     AAFLAAYAVVLSRYAGRPDVVVGAPVSGRTRVELEPIAGPFADVVPVRVPLAGEPSFAE
                     LLVRVRDAAAQAVSHDEVPLGVLVEELGVGLSDAVRFTFPPPAAPALDLPGVTVRSRVA
                     LSDAATADLDLRVDEHGALTLEHRTDQGFADWVLRSVVAVLEHATADSAVSELPVPVPE
                     DTWSAVAEPSPAEPSPNGAVRSAAAGAAEPEVDVSPVPARGEIEQAMAKTWADLLRRPG
                     RVGVRDNLFGLGGGSLAAVRFASLVADTYGVTLPLPLIFASPTVAALAEFVSAELEAAR
                     TAREAEADQAARLATLSDDELDDLLRAVVATRERRRSTGGDGR"
     aSDomain        3264..4022
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14530_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-57"
                     /label="IOD16_RS14530_Condensation_LCL.1"
                     /locus_tag="IOD16_RS14530"
                     /protein_end="272"
                     /protein_start="19"
                     /score="187.2"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: HRVVADG"
                     /tool="antismash"
                     /translation="SHATWLDGPVDPAALRRAVDVVVARHPVLRTHVTASGEQVVSETG
                     RVVLEHVVLPGDVARAESVAAELAERPFDLSREPLTRAAVIEVGAGRWLFALVAHRVVA
                     DGSTLAMLLADLSTVYREGLSELPSSWMDYGDYAVWQRERLRGEELARQLAHWREVLRD
                     APAPVRLPAGRRAASLTAVVDPTAVRRLAAVAEGAGATLPAAFLAAYAVVLSRYAGRPD
                     VVVGAPVSGRTRVELEPIAGPFADVVPVRVP"
     aSModule        3264..4739
                     /domains="nrpspksdomains_IOD16_RS14530_Condensation_LCL.1"
                     /domains="nrpspksdomains_IOD16_RS14530_PCP.1"
                     /incomplete
                     /locus_tags="IOD16_RS14530"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3276..3359
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14530_0001"
                     /evalue="7.20E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="IOD16_RS14530"
                     /protein_end="51"
                     /protein_start="23"
                     /score="40.9"
                     /tool="antismash"
                     /translation="WLDGPVDPAALRRAVDVVVARHPVLRTH"
     CDS_motif       3663..3698
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14530_0002"
                     /evalue="9.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="IOD16_RS14530"
                     /protein_end="164"
                     /protein_start="152"
                     /score="18.1"
                     /tool="antismash"
                     /translation="YGDYAVWQRERL"
     CDS_motif       3858..3914
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14530_0003"
                     /evalue="1.80E-03"
                     /label="Cy4"
                     /locus_tag="IOD16_RS14530"
                     /protein_end="236"
                     /protein_start="217"
                     /score="11.4"
                     /tool="antismash"
                     /translation="GATLPAAFLAAYAVVLSRY"
     CDS_motif       3927..4016
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14530_0004"
                     /evalue="9.50E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="IOD16_RS14530"
                     /protein_end="270"
                     /protein_start="240"
                     /score="34.1"
                     /tool="antismash"
                     /translation="DVVVGAPVSGRTRVELEPIAGPFADVVPVR"
     CDS_motif       4065..4136
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14530_0005"
                     /evalue="1.60E-03"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IOD16_RS14530"
                     /protein_end="310"
                     /protein_start="286"
                     /score="10.7"
                     /tool="antismash"
                     /translation="RDAAAQAVSHDEVPLGVLVEELGV"
     aSDomain        4533..4739
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14530_PCP.1"
                     /evalue="9.20E-18"
                     /label="IOD16_RS14530_PCP.1"
                     /locus_tag="IOD16_RS14530"
                     /protein_end="511"
                     /protein_start="442"
                     /score="56.2"
                     /tool="antismash"
                     /translation="EQAMAKTWADLLRRPGRVGVRDNLFGLGGGSLAAVRFASLVADTY
                     GVTLPLPLIFASPTVAALAEFVSA"
     gene            4886..6253
                     /locus_tag="IOD16_RS14535"
                     /old_locus_tag="IOD16_14540"
     CDS             4886..6253
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (81-427). E-value:
                     3.1e-29. Score: 94.2. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14535_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331884.1"
                     /locus_tag="IOD16_RS14535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14540"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_328809456.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4e-27, bitscore:
                     94.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTPATAGDLADLDTGTLFGALEDPALNSMNFLNEVAIHYPDAI
                     PLAAGRPSEEFFELEDVHRYLRIFSEHLGRRLTEAQVRRTVLQYGRTKGIIHELVAENL
                     RLDEDISVDPESVVVTAGCQEAMFLVLRALRADDRDVLLAVSPTYVGLTGAARLVDLPV
                     RPVRTGEHGIDLADLVAVIRRERAAGRRPRACYVVPDFANPSGLSLDLATRRRLLEVAA
                     AEDVLLIEDNPYGLFHGDADRVPTLKALDAARRVVYLGSFAKSVLPGARVGYVVADQRV
                     SGADGTTGLFADQLSKIKSMLTVNTSPIAQAVVGGKLLAHGCRLAGATAPERRLYDRNL
                     RRLVTGLAERFPPGSDVTWTVPTGGFFVVVTVPFAVDDRLLERSARDYGVLWTPMGHFY
                     DGVTAVRALRLSCSAVSVDQIDRGLDRLAALINDRSGRSAGTIDHGHLADSARGEP"
     aSDomain        5129..6166
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14535_Aminotran_1_2.1"
                     /evalue="3.10E-29"
                     /label="IOD16_RS14535_Aminotran_1_2.1"
                     /locus_tag="IOD16_RS14535"
                     /protein_end="427"
                     /protein_start="81"
                     /score="94.2"
                     /tool="antismash"
                     /translation="VRRTVLQYGRTKGIIHELVAENLRLDEDISVDPESVVVTAGCQEA
                     MFLVLRALRADDRDVLLAVSPTYVGLTGAARLVDLPVRPVRTGEHGIDLADLVAVIRRE
                     RAAGRRPRACYVVPDFANPSGLSLDLATRRRLLEVAAAEDVLLIEDNPYGLFHGDADRV
                     PTLKALDAARRVVYLGSFAKSVLPGARVGYVVADQRVSGADGTTGLFADQLSKIKSMLT
                     VNTSPIAQAVVGGKLLAHGCRLAGATAPERRLYDRNLRRLVTGLAERFPPGSDVTWTVP
                     TGGFFVVVTVPFAVDDRLLERSARDYGVLWTPMGHFYDGVTAVRALRLSCSAVSVDQID
                     RGLDRL"
     misc_feature    6304..6318
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.6"
                     /tool="antismash"
     gene            6342..7751
                     /locus_tag="IOD16_RS14540"
                     /old_locus_tag="IOD16_14545"
     CDS             6342..7751
                     /NRPS_PKS="Domain: AMP-binding (40-377). E-value: 8e-40.
                     Score: 128.6. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14540_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681761.1"
                     /locus_tag="IOD16_RS14540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14545"
                     /product="fatty acid--CoA ligase family protein"
                     /protein_id="WP_201440481.1"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-34, bitscore:
                     116.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKGLASSGFELVTSPEWVDEILLRGADDDICLYSGGPVDRGALR
                     RMVADAQARLAAAGLGPGGSLALRLPPSTAYVANLLAGWRLGAQVSLLDHRLTAYEVEL
                     ALGRLAPQVVVEPGRVTSSPLSAFAEVEETVTARSGRPAGTPHAVIQFSSGSTGPSKVI
                     GRTAADLVAEIERYTRIDGVPLPGERIVVLASMVHVLGLVGALLYGLHAGVQIRPPDRL
                     TGDSVLDAVAAEPTPATVLGVPFHIGLLASVVEPPSLPQLKRMTTGGEPVPAATAAAFT
                     GKYGVPLGNMWGMTEVGVIATDLFGEHRPALTPAPGLSVVERDGELLVSRPESPYVGLS
                     DPDRWADGWLRTRDAGAVDPDTGLVTVKGRLDSQVSVGGLKVDLTEVEATVAGLPGVVA
                     AVVLHDDVITAYAQLDAPATAASVQAGLAERLAAYKRPRRLHVLDAMPRTITGKLVRDR
                     SVLRQAASGGM"
     aSDomain        6462..7472
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14540_AMP-binding.1"
                     /evalue="8.00E-40"
                     /label="IOD16_RS14540_AMP-binding.1"
                     /locus_tag="IOD16_RS14540"
                     /protein_end="377"
                     /protein_start="40"
                     /score="128.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RGALRRMVADAQARLAAAGLGPGGSLALRLPPSTAYVANLLAGWR
                     LGAQVSLLDHRLTAYEVELALGRLAPQVVVEPGRVTSSPLSAFAEVEETVTARSGRPAG
                     TPHAVIQFSSGSTGPSKVIGRTAADLVAEIERYTRIDGVPLPGERIVVLASMVHVLGLV
                     GALLYGLHAGVQIRPPDRLTGDSVLDAVAAEPTPATVLGVPFHIGLLASVVEPPSLPQL
                     KRMTTGGEPVPAATAAAFTGKYGVPLGNMWGMTEVGVIATDLFGEHRPALTPAPGLSVV
                     ERDGELLVSRPESPYVGLSDPDRWADGWLRTRDAGAVDPDTGLVTVKGRLDSQVSV"
     CDS_motif       7446..7505
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14540_0001"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="IOD16_RS14540"
                     /protein_end="388"
                     /protein_start="368"
                     /score="14.4"
                     /tool="antismash"
                     /translation="GRLDSQVSVGGLKVDLTEVE"
     gene            7800..8054
                     /locus_tag="IOD16_RS14545"
                     /old_locus_tag="IOD16_14550"
     CDS             7800..8054
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681763.1"
                     /locus_tag="IOD16_RS14545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14550"
                     /product="hypothetical protein"
                     /protein_id="WP_236594981.1"
                     /transl_table=11
                     /translation="MSQEETPGRDDVLRMLASLDGRPSEDVPELIESMELAWLVHQVEQ
                     RYGVRMELDSGQYSRMTTVSGAADVLREVIGMPDEHIRD"
     gene            8035..9123
                     /gene="hppD"
                     /locus_tag="IOD16_RS14550"
                     /old_locus_tag="IOD16_14555"
     CDS             8035..9123
                     /EC_number="1.13.11.27"
                     /GO_function="GO:0003868 - 4-hydroxyphenylpyruvate
                     dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hppD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700320.1"
                     /locus_tag="IOD16_RS14550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14555"
                     /product="4-hydroxyphenylpyruvate dioxygenase"
                     /protein_id="WP_201440482.1"
                     /transl_table=11
                     /translation="MNISGIDHIELYVGDAKQTAFYLCSAFGFEVCGQGGPETGLAGQR
                     SLLLRQGDIQVVLTTGLVPDHPATEYVRRHGDGVAVVGIGVDDVAAAYRTLTERGAEPV
                     SPPREYASAAAGGDDRRVVVAEVSGFSDVTHRLVERHGSPREFLPGAIEVAEPHPDTDV
                     KLLRAIDHLAICVPAGGLASTARYYVDVFGFEQIFEEYVEVGGQGMDSRVVQSPSGHVT
                     FTLIEPDPERQPGQIDNFLTWHAGAGVQHVAFGTDDIVKAVGTLGDKGVRFLGTPGSYY
                     DTLEERVGHLDAPLDELRRLGVLVDRDHWGQLLQIFTESMHVRRTLFLEIIERRGALTF
                     GSGNIKALYEAKQGELSGTTAP"
     misc_feature    8065..8067
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9134..9149
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            9135..10034
                     /locus_tag="IOD16_RS14555"
                     /old_locus_tag="IOD16_14560"
     CDS             9135..10034
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681769.1"
                     /locus_tag="IOD16_RS14555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14560"
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_201440483.1"
                     /sec_met_domain="PhyH (E-value: 1.9e-21, bitscore: 76.1,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEFTLTDHERALLPSDDDVRFFAEHGWYLSKKLFSDDEVDELTA
                     AVGRYYSGERSRRLPTRPPRLAYWTPEHGDVQRHNDYVHYESDGIAKALLKPLIGAVAA
                     RLAEADEIRVFQSTLIYKPPIAEEPSNVVPWHFDKHYWSSSSSDRMLTAFIPFHDCDEE
                     LGTITMVDGSHLWEEVGSDDSATKHFAERDADHLENLLTANAEHNGTTVRKIPMIIPKG
                     HMSFHHCRTYHGSGPNRSTRPRQAISLHLQDGDNAYREFPLSDGNLAFYNHDSLVRRTA
                     DGRPDYADPEFCPPVWRS"
     gene            10022..11023
                     /locus_tag="IOD16_RS14560"
                     /old_locus_tag="IOD16_14565"
     CDS             10022..11023
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681780.1"
                     /locus_tag="IOD16_RS14560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14565"
                     /product="thiamine pyrophosphate-dependent dehydrogenase E1
                     component subunit alpha"
                     /protein_id="WP_236594982.1"
                     /transl_table=11
                     /translation="MALLTAVAAHAPDSDVGLYRTVRLIRRFEERAVELVRSGDIIGGI
                     HPYTGQEAVAAGVCAALRVDDMITSTHRGHGHVLAKGADPARTLAELAGRATGLNRGRG
                     GSMHAADFGSGILGANAIVGANGAITAGAAWAARQDGGDQVAVSFFGDGAVNQGVLLEA
                     MNLAALWRLPTLFVCENNGYATTLTVADAVAGTITGRGEAFGMPSVTVDGMDPRAVLDA
                     AREAVDRARAGGGPSLVECLTYRFDAHHTWEHKARVRYRDDDEVRSGRERDPVEIQGAR
                     LTGDERTSVDAEVEAVVDAAVAFALDSPHPDPVGALDHLYATGMRARPGGGG"
     gene            11023..11991
                     /locus_tag="IOD16_RS14565"
                     /old_locus_tag="IOD16_14570"
     CDS             11023..11991
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681781.1"
                     /locus_tag="IOD16_RS14565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14570"
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /protein_id="WP_201440484.1"
                     /transl_table=11
                     /translation="MPWLSYRKALNRALVDELARDPAVFVLGEDVRVAVSNVTAGLLKR
                     FGPDRVLDTPLSEQAFTSFATGAALRGRRPVIEFQIPALLYLAFEQIVNQAHKFSLMTG
                     GQTRVPVTYLVPGSGSRTGWAGQHSDHPYALFAHAGVKTVVPATPEDAYGLLATAIRDD
                     DPVVVFAPAAALDVRVDVDHDGLAPVPLGVGRVHREGEDVTVVAVGHLVHDAVAVAEEL
                     AGDVSVEVFDPRTVYPFDWDGLAASLAKTGRLVVVDDSNRMCGIAAEVLATAAEGCDLV
                     VPPVRVTRPDGAVVPFARGLDLAVQPDRAQLTAAIRKVLKQ"
     gene            12006..12926
                     /locus_tag="IOD16_RS14570"
                     /old_locus_tag="IOD16_14575"
     CDS             12006..12926
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681758.1"
                     /locus_tag="IOD16_RS14570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14575"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_201440485.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.8e-09, bitscore:
                     36.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLDPQLTTAPGNTASPPLYTLSVEEARAADLAAIRAAAGAGEPV
                     RHVTDRRLPGPGGDLPIRVYRPVDAAGPLPTVVYFFGGGWALGSIDTSDEICRALANAV
                     PCQVITVGYRLAPEHKFPAAVDDCRTAVAWIAANAAELGVDPDRLAVAGDSAGGNLAAV
                     VTLDRDGPPLAAQVLVYPNTDHRGDTGSMRENDDPAAFNRRSVAWYWGHYLANPDDGRD
                     PRASPLLAEDLTGLPPALVITAEHDPLRDEGEQYADRLREAGVPVVATRYLGTAHGFFA
                     MSGVVDAAREARAEVAAFLRAHLGP"
     gene            13053..14198
                     /locus_tag="IOD16_RS14575"
                     /old_locus_tag="IOD16_14580"
     CDS             13053..14198
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102302.1"
                     /locus_tag="IOD16_RS14575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14580"
                     /product="glycosyltransferase"
                     /protein_id="WP_201440486.1"
                     /sec_met_domain="MGT (E-value: 9.5e-96, bitscore: 320.2,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILFSSLGLYGHTFPLLPLAVAARELGHDVDYFTGKGFADVLAS
                     QGIEHVEGGLSPRKAFEQAMAGTRPGTPGDVDVERVAFTFASVLPRSFATGLAPVLAER
                     KPDLVVHEFGNPGAGLAAKAAGVPALCHSYGRMWQEPDFAAPARDYLTALGAELGVEVP
                     RTDSMALGHPYLDICPPSVQNPEFLASSAHRIPLRPVAFAAAGELPSWVEEHREPLVYL
                     TLGTAFSQATLLRTAVDGLAVLGARVLVAAGPKVDPGTLGELPDNVVVLPWVPQADLLP
                     HADLVVHHGGAGTTLGTFGAGVPQLVLPQAADQFNNGVVVTEAGLGDHLRPEDATAEAI
                     TTKARHLLTDEAVRAAAHAMAAEVAGMPSPHDVARTLPDYA"
     gene            complement(14246..16789)
                     /locus_tag="IOD16_RS14580"
                     /old_locus_tag="IOD16_14585"
     CDS             complement(14246..16789)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024816.4"
                     /locus_tag="IOD16_RS14580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14585"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_201440487.1"
                     /transl_table=11
                     /translation="MDDVRRPSQWAWAQSGSSVQQAGRDIRNDTYDVRLSPGHGPGLVS
                     VEAPWGRLPEHLRGRDDISADLAGLVADPPGRLVVLHGAGGYGKSTLALWLARHAADRQ
                     VPVWWVSADNAQTLADGLREVALQAGANPVSVELAWSGRASAPDLLWRALDAVDGRWVL
                     VVDNADDPDVLSGGGRLSEGTGWLRPPEPGHGLVVVTSRQGNPRAWPRHTDQRLLTGID
                     AADAGLVLTDLAGPRAGSLPEAQRLGDRLGGLPLALRLAGSYLAAGADALLVPGAELPR
                     TFADYQAALDARVDVLDAPPADHDEERDERELISRTWELSLDLLARRGHPRARPLLRLL
                     SFFGQAPIPVDVLDAALLATVPTWAATTPETVSRLLRVLLDLGLVDRADLPDRQALTLH
                     RLIRDTNRHHAAAEPDVHQHAIALVKLVHAATRTPLITQEAWSRRHALASHAEAALELC
                     RAHLDHVPPDLVEQAITAAREAAFFRRHVHDLDQAAVDFQVILDCRRQTLGEHHPDTLA
                     TRTDLAVVRGTPALPGQPDQAEAELTEVLDVQRRVLGDHHPDTLRTRHALAGRLAERGD
                     WPAAEQAHRRTTEIAQRELGPDHEATLAGRHALAQALYSLGRSAEAETEFHAALEAHRR
                     VFGEEHANTLATWHGYATVLADLEKPAAAAAEFRSILRIQARKSGEHSEPALSARHGLG
                     HSLRRLGRNTEAKAEYEAVLDLGRPTLGDEHPGILTCRANLAALRAELGDTASAETELR
                     DVLEIQCCVHGLAHPATLQTRLDLASLMALNGDTPSAEALLWQVVMLGSPTLGLDHPMI
                     RLCRLLLNTVTSSPTPRRAARRPRRTGPARRRRRR"
     misc_feature    complement(16963..16977)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            16973..17971
                     /locus_tag="IOD16_RS14585"
                     /old_locus_tag="IOD16_14590"
     CDS             16973..17971
                     /EC_number="2.7.7.6"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646287.1"
                     /locus_tag="IOD16_RS14585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14590"
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="WP_201440488.1"
                     /transl_table=11
                     /translation="MTDESLPSDDATVVAAVRSGDTARFALLTERYRRELQVHCYRMLA
                     NYEDAQDLTQETFLRAWHKRESFRGHAALRTWLYRIATNACLDFLEKRDDRTPVPSELP
                     DSEVPHLQPYPDRMLPEDPQESVVARETIELAFIVAVQHLPPRQRAVFILRDVLGWPAS
                     NAADALELTVASVTSALQRARVTMRAQLPDRRLDWRGTATHELSSDERDVVRSYIDAHE
                     RNDLDGLMGLLRDDLRFAMLPDPGTVTRTAKDAVDGWVSGGLFGPGHDDWRGVATAVNR
                     MPAAVLYLRTPDDPRHRLFAVAVLHVVDGKIARLTGFDAADKPWLDLPPTL"
     gene            complement(18083..18667)
                     /locus_tag="IOD16_RS14590"
                     /old_locus_tag="IOD16_14595"
     CDS             complement(18083..18667)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673908.1"
                     /locus_tag="IOD16_RS14590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14595"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_201440489.1"
                     /transl_table=11
                     /translation="MRKLIFAMNVTLDGYIAATGDDIGWSGGDGPDSSPGDELFQWWSD
                     RVGATGLALYGRKLWEAMSPHWPTADQRPGATPAEIEFARRWRDMPKVVFSSTISTVDW
                     NTRLVTGDAVAEITRLKADDGGPMDIGGATLAAAAMRAGLIDEYVLVTAPVLVGGGTPF
                     FTALDNWVNLTLVQTRTFPGGVVLTRYETRR"
     gene            18828..19304
                     /locus_tag="IOD16_RS14595"
                     /old_locus_tag="IOD16_14600"
     CDS             18828..19304
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS14595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_14600"
                     /product="hypothetical protein"
                     /protein_id="WP_201440490.1"
                     /transl_table=11
                     /translation="MSRVVTWSGNTSSADAAAAFERCVEHAGGGTFVMGHAHLRDDGRL
                     VVGAISGDTIMKCGVDEFGVRTSTTDPARHPVRETGFGLPLSTGYDDRLAATVVGYAGD
                     DVVAVNFRIPDGRVIPARVRQGVYLLGLPAETNHDYGDLTHEAFDATGAVIPGR"
     gene            20001..27296
                     /locus_tag="IOD16_RS14600"
                     /old_locus_tag="IOD16_14605"
     CDS             20001..27296
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (9-428). E-value:
                     1.3e-160. Score: 526.9. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14600_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (531-821). E-value: 2.2e-101.
                     Score: 331.1. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14600_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (886-1043). E-value: 1.2e-34.
                     Score: 112.0. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14600_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1324-1511). E-value: 9.1e-57.
                     Score: 183.9. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14600_cMT.1"
                     /NRPS_PKS="Domain: PKS_ER (1737-2051). E-value: 5.6e-110.
                     Score: 359.3. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14600_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2071-2250). E-value: 7.7e-58.
                     Score: 187.4. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14600_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (2350-2414). E-value:
                     5.2e-12. Score: 37.9. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14600_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="IOD16_RS14600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14605"
                     /product="type I polyketide synthase"
                     /protein_id="WP_201440491.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.2e-84, bitscore:
                     280.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.7e-158, bitscore:
                     526.9, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.9e-99, bitscore: 331.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 1.4e-06, bitscore: 27.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1e-19, bitscore:
                     69.7, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8e-55, bitscore:
                     184.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-09, bitscore:
                     36.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPNCPTDAVAIVGAACRLPGGIADLDQLWTALSEGRDLIGEVPE
                     GRFDPDRFFDPDPLRPGKSYSFAGGFLSDVRGFDAEYFGISPREAAAMDPQQRMLLEMG
                     TEALDDAGLDRRELAGSDTAVFLGVSGAGYGLLQLNDLRTADVHSMIGGTASIIPNRLS
                     YALDLRGPSMVVDTACSSAMVALHQACEAVRSGRSALALAGGINLLLDPMTFVGFSKAM
                     MLSPTFRCRSFSADADGYVRAEGGGLVVLKRLSDALADGDRVHAVLLATGTNTDGRTNG
                     LAMPSAHAQADLLRGIYDGLGVDADDLVYLEAHGTGTPVGDPVECTALGEALGRRRQAG
                     PLPIGSVKTNLGHLESASGMPGLFKAMLVLRHGVVPPSLHGEQPNPEIDFAGLGLHPVS
                     QPLPVGPGVVGVNSFGFGGTNAHAVLAPAPVAGDPPRTPGGALPVMVSARSGEALVAAV
                     GRVRDRFAAASAEEFYDLAYTTCLRRTPDAHRVVVVAADPAEAADRLDAALRGDHEVAA
                     ALDVATTRDGVAFAFSGNGSQWYGMGRDLLATEPAFRAAVTAVDAALAPHLGWSVVEEL
                     AAAEDRLHDTAVAQPLLFAVQWGLVALLRERGVVPSVVLGHSVGEVAAACVAGALDLDT
                     AAKVVAERSLAQARTAGAGRMAAVGLSHERAEEVLAEFPGQLVPAAVNSAQDVTVAGDA
                     GAVTRLVEKLIANDVFARELDLDYAFHSPAMDPVEDRVRTGLAGVRSAEPEIPMLSTVT
                     GMPVRAGELDADYWWRNVRQPVLFHQAASALAEQGIGVVVEIGPHPVLTGYLRRTGGEP
                     LKTVATLNRGGTGRALAERVVAGVSAAGGALRWSRYFPDRGRVCDLPTYPWQREEHWKG
                     VPEAWVRTSGTGRLDHPLLGERMPALEPIWFAAVEPARTPWMADHRVGGSVVVPATGYV
                     EMALAAGRRVLGDRVEVTGLDITRALALSWLPTMDVRTQVSLSDEDGLFRVASRQGDDG
                     DWTLHARGRVRRLVADAPVAPREPAEPADHVPAAEHYTACDRAGISYGPAFRGLREIRV
                     RPGEAWADYEFPLSCDDHEVHPALLDLALQAGIPLLRLDTPDSRAYLPSSVDRVRRWRQ
                     PTAHGRIRVQVRSHTAREACWDISVLDADGEVAVELTGCRLQSFGAVLRAGVQRLETVL
                     RAAPRPGEQVGPWPVPALPPVTVTPAPCHAAVRGMATEAGARFAVAAVESLLPGRVAFT
                     TDDLLAAGVLPEYRRLVDVLLRSASAHGRVRADGPVWHLIGSPDLEGFARRHAEFPEAA
                     ALLALHLGCGLNLVDVLCGRVDLEDLVLGDTEATAYFHDLNPVAASYNEAVRESVRAIV
                     QRWPADRPLRVLEVGAGTGGTTGFVLPVLPADRTRYVFSDVSAGCLTGARTRFGSWDFV
                     EYRTFDLDTDPDPREFPDGGFDLVIAANALHAATDLRAAVGRVARLLCPGGRLIAVESH
                     DVAMLALTSGLSRGFWSYSDVSSRPDSPLVPVAEWPELLRTGGFDRVDVAEDGERTGFS
                     VLTAAVGDTAATPTVPTTTARWVVVLDDPEDRERADAVVAALRGAGADTTAVTADVPDW
                     EAVLVDADGVAVVLGGAAGDAADRAVRAAAVLRGIGAAATRRDDAEPLPLWVVARPSGA
                     LPAPESPDDPVDAATWGTARTLGNENRSVAVRRVSWDHGDDPAASAGRLVAELLDPSDE
                     DEVVLTASGRFVPRTVPARTPTRADAASARLVVREPSLFYRLTWVEQEVPEPGAGQVVV
                     RVAAAALNYRDIMVATGLLPPAAEAGAGIDSASTLGLEFAGVVTAVGPDVSAVRPGDRV
                     FGMAPGAFASHVLTRVEQLAPVPDGMSCTEAATMPVAWITVHHGLRALARLRAGETVLV
                     HGAAGGVGIAAVGLARRTGATVIATAGSELKRDYLRAIGVDHVVDSRSVKFADDVLRIT
                     GGRGVDIVLNSLSGEALVRGLEVLAPCGRFVEIGKRDIYQDSRLAMRPLADNISLFAVD
                     IANLASHDRDWAVRCAEEVFAAVTAGEYTPLPHRVYPVTRIDEAFKLMQHSRHIGKVVV
                     SFDEAVPVERTPGRLALDPGATYLVVGGLSGFGAATARRLVDRGARRLVLVGRRGPATE
                     EARDLVEELTARGVRVDAHAADVTDRSAMAAVLGSIPPDHPLRGVVHAAMVLDDRPLED
                     LDDNAFHTALDPKLRGALVLDDLTDGLELDFFVLYSSGAALVGNFKQANYVAGNLFLEA
                     LTRARRRRGRPALAVQWGAIADTGYVAREAMGEQLAKLGLAPCHSDQALDVLEDLLCVP
                     EADVVAVGDFRFEQAAAVLSASATPRLAGLLPEDGGESGQELRDLLRRIDDFPRAEALQ
                     LIEDVLVTELAAIMQTTPDRVDRTKTLSELGVDSLMGMELLVVLRHRFQYQVSPMELMQ
                     TGGRISAMAEPALDHLIRMAAAERAL"
     aSDomain        20028..21284
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14600_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.30E-160"
                     /label="IOD16_RS14600_PKS_KS.1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="428"
                     /protein_start="9"
                     /score="526.9"
                     /tool="antismash"
                     /translation="VAIVGAACRLPGGIADLDQLWTALSEGRDLIGEVPEGRFDPDRFF
                     DPDPLRPGKSYSFAGGFLSDVRGFDAEYFGISPREAAAMDPQQRMLLEMGTEALDDAGL
                     DRRELAGSDTAVFLGVSGAGYGLLQLNDLRTADVHSMIGGTASIIPNRLSYALDLRGPS
                     MVVDTACSSAMVALHQACEAVRSGRSALALAGGINLLLDPMTFVGFSKAMMLSPTFRCR
                     SFSADADGYVRAEGGGLVVLKRLSDALADGDRVHAVLLATGTNTDGRTNGLAMPSAHAQ
                     ADLLRGIYDGLGVDADDLVYLEAHGTGTPVGDPVECTALGEALGRRRQAGPLPIGSVKT
                     NLGHLESASGMPGLFKAMLVLRHGVVPPSLHGEQPNPEIDFAGLGLHPVSQPLPVGPGV
                     VGVNSFGFGGTNAHAVLAPA"
     aSModule        20028..27242
                     /complete
                     /domains="nrpspksdomains_IOD16_RS14600_PKS_KS.1"
                     /domains="nrpspksdomains_IOD16_RS14600_PKS_AT.1"
                     /domains="nrpspksdomains_IOD16_RS14600_PKS_DH.1"
                     /domains="nrpspksdomains_IOD16_RS14600_cMT.1"
                     /domains="nrpspksdomains_IOD16_RS14600_PKS_ER.1"
                     /domains="nrpspksdomains_IOD16_RS14600_PKS_KR.1"
                     /domains="nrpspksdomains_IOD16_RS14600_PP-binding.1"
                     /locus_tags="IOD16_RS14600"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20508..20555
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0001"
                     /evalue="4.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="185"
                     /protein_start="169"
                     /score="18.7"
                     /tool="antismash"
                     /translation="GPSMVVDTACSSAMVA"
     CDS_motif       20697..20735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0002"
                     /evalue="5.40E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="245"
                     /protein_start="232"
                     /score="13.1"
                     /tool="antismash"
                     /translation="FSADADGYVRAEG"
     CDS_motif       20928..20975
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0003"
                     /evalue="5.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="325"
                     /protein_start="309"
                     /score="12.3"
                     /tool="antismash"
                     /translation="YLEAHGTGTPVGDPVE"
     CDS_motif       21033..21077
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0004"
                     /evalue="1.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="359"
                     /protein_start="344"
                     /score="11.0"
                     /tool="antismash"
                     /translation="GSVKTNLGHLESASG"
     CDS_motif       21588..21641
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0005"
                     /evalue="3.50E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="547"
                     /protein_start="529"
                     /score="16.3"
                     /tool="antismash"
                     /translation="FAFSGNGSQWYGMGRDLL"
     aSDomain        21594..22463
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14600_PKS_AT.1"
                     /evalue="2.20E-101"
                     /label="IOD16_RS14600_PKS_AT.1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="821"
                     /protein_start="531"
                     /score="331.1"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="FSGNGSQWYGMGRDLLATEPAFRAAVTAVDAALAPHLGWSVVEEL
                     AAAEDRLHDTAVAQPLLFAVQWGLVALLRERGVVPSVVLGHSVGEVAAACVAGALDLDT
                     AAKVVAERSLAQARTAGAGRMAAVGLSHERAEEVLAEFPGQLVPAAVNSAQDVTVAGDA
                     GAVTRLVEKLIANDVFARELDLDYAFHSPAMDPVEDRVRTGLAGVRSAEPEIPMLSTVT
                     GMPVRAGELDADYWWRNVRQPVLFHQAASALAEQGIGVVVEIGPHPVLTGYLRRTGGEP
                     LKTVATLNR"
     CDS_motif       21822..21932
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0006"
                     /evalue="4.00E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="644"
                     /protein_start="607"
                     /score="51.1"
                     /tool="antismash"
                     /translation="GVVPSVVLGHSVGEVAAACVAGALDLDTAAKVVAERS"
     CDS_motif       22284..22331
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0007"
                     /evalue="5.50E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="777"
                     /protein_start="761"
                     /score="12.5"
                     /tool="antismash"
                     /translation="LDADYWWRNVRQPVLF"
     aSDomain        22659..23129
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14600_PKS_DH.1"
                     /evalue="1.20E-34"
                     /label="IOD16_RS14600_PKS_DH.1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1043"
                     /protein_start="886"
                     /score="112.0"
                     /tool="antismash"
                     /translation="HPLLGERMPALEPIWFAAVEPARTPWMADHRVGGSVVVPATGYVE
                     MALAAGRRVLGDRVEVTGLDITRALALSWLPTMDVRTQVSLSDEDGLFRVASRQGDDGD
                     WTLHARGRVRRLVADAPVAPREPAEPADHVPAAEHYTACDRAGISYGPAFRGL"
     CDS_motif       22734..22811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0008"
                     /evalue="8.10E-13"
                     /label="PKSI-DH_m2"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="937"
                     /protein_start="911"
                     /score="40.7"
                     /tool="antismash"
                     /translation="WMADHRVGGSVVVPATGYVEMALAAG"
     CDS_motif       23742..23777
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0009"
                     /evalue="2.90E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1259"
                     /protein_start="1247"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="SASAHGRVRADG"
     CDS_motif       23880..23903
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0010"
                     /evalue="1.40E+01"
                     /label="PKSI-ER_m1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1301"
                     /protein_start="1293"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="GLNLVDVL"
     aSDomain        23973..24533
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14600_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="9.10E-57"
                     /label="IOD16_RS14600_cMT.1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1511"
                     /protein_start="1324"
                     /score="183.9"
                     /tool="antismash"
                     /translation="NPVAASYNEAVRESVRAIVQRWPADRPLRVLEVGAGTGGTTGFVL
                     PVLPADRTRYVFSDVSAGCLTGARTRFGSWDFVEYRTFDLDTDPDPREFPDGGFDLVIA
                     ANALHAATDLRAAVGRVARLLCPGGRLIAVESHDVAMLALTSGLSRGFWSYSDVSSRPD
                     SPLVPVAEWPELLRTGGFDRVDVA"
     aSDomain        25212..26153
                     /ASF="ER domain putatively catalyzing 2R-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14600_PKS_ER.1"
                     /evalue="5.60E-110"
                     /label="IOD16_RS14600_PKS_ER.1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="2051"
                     /protein_start="1737"
                     /score="359.3"
                     /tool="antismash"
                     /translation="RLTWVEQEVPEPGAGQVVVRVAAAALNYRDIMVATGLLPPAAEAG
                     AGIDSASTLGLEFAGVVTAVGPDVSAVRPGDRVFGMAPGAFASHVLTRVEQLAPVPDGM
                     SCTEAATMPVAWITVHHGLRALARLRAGETVLVHGAAGGVGIAAVGLARRTGATVIATA
                     GSELKRDYLRAIGVDHVVDSRSVKFADDVLRITGGRGVDIVLNSLSGEALVRGLEVLAP
                     CGRFVEIGKRDIYQDSRLAMRPLADNISLFAVDIANLASHDRDWAVRCAEEVFAAVTAG
                     EYTPLPHRVYPVTRIDEAFKLMQHSRHIGKVVV"
     CDS_motif       25287..25319
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0011"
                     /evalue="1.50E-02"
                     /label="PKSI-ER_m1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1773"
                     /protein_start="1762"
                     /score="8.7"
                     /tool="antismash"
                     /translation="LNYRDIMVATG"
     CDS_motif       25371..25409
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0012"
                     /evalue="3.60E-04"
                     /label="PKSI-ER_m2"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1803"
                     /protein_start="1790"
                     /score="13.4"
                     /tool="antismash"
                     /translation="LGLEFAGVVTAVG"
     CDS_motif       25536..25580
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0013"
                     /evalue="8.30E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1860"
                     /protein_start="1845"
                     /score="12.8"
                     /tool="antismash"
                     /translation="AATMPVAWITVHHGL"
     CDS_motif       25605..25667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0014"
                     /evalue="2.00E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1889"
                     /protein_start="1868"
                     /score="23.4"
                     /tool="antismash"
                     /translation="GETVLVHGAAGGVGIAAVGLA"
     CDS_motif       25677..25727
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0015"
                     /evalue="1.70E-04"
                     /label="PKSI-ER_m6"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1909"
                     /protein_start="1892"
                     /score="14.4"
                     /tool="antismash"
                     /translation="GATVIATAGSELKRDYL"
     CDS_motif       25797..25835
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0016"
                     /evalue="1.60E-05"
                     /label="PKSI-ER_m7"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1945"
                     /protein_start="1932"
                     /score="17.2"
                     /tool="antismash"
                     /translation="TGGRGVDIVLNSL"
     CDS_motif       25881..25910
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0017"
                     /evalue="2.20E-03"
                     /label="PKSI-ER_m8"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="1970"
                     /protein_start="1960"
                     /score="11.3"
                     /tool="antismash"
                     /translation="GRFVEIGKRD"
     CDS_motif       26106..26153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0018"
                     /evalue="8.30E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="2051"
                     /protein_start="2035"
                     /score="18.7"
                     /tool="antismash"
                     /translation="AFKLMQHSRHIGKVVV"
     aSDomain        26214..26750
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14600_PKS_KR.1"
                     /evalue="7.70E-58"
                     /label="IOD16_RS14600_PKS_KR.1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="2250"
                     /protein_start="2071"
                     /score="187.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="ATYLVVGGLSGFGAATARRLVDRGARRLVLVGRRGPATEEARDLV
                     EELTARGVRVDAHAADVTDRSAMAAVLGSIPPDHPLRGVVHAAMVLDDRPLEDLDDNAF
                     HTALDPKLRGALVLDDLTDGLELDFFVLYSSGAALVGNFKQANYVAGNLFLEALTRARR
                     RRGRPALAVQWGAIAD"
     CDS_motif       26217..26315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0019"
                     /evalue="1.20E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="2105"
                     /protein_start="2072"
                     /score="43.6"
                     /tool="antismash"
                     /translation="TYLVVGGLSGFGAATARRLVDRGARRLVLVGRR"
     CDS_motif       26592..26702
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS14600_0020"
                     /evalue="1.20E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="2234"
                     /protein_start="2197"
                     /score="56.4"
                     /tool="antismash"
                     /translation="LDFFVLYSSGAALVGNFKQANYVAGNLFLEALTRARR"
     aSDomain        27051..27242
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14600_PP-binding.1"
                     /evalue="5.20E-12"
                     /label="IOD16_RS14600_PP-binding.1"
                     /locus_tag="IOD16_RS14600"
                     /protein_end="2414"
                     /protein_start="2350"
                     /score="37.9"
                     /tool="antismash"
                     /translation="VLVTELAAIMQTTPDRVDRTKTLSELGVDSLMGMELLVVLRHRFQ
                     YQVSPMELMQTGGRISAMA"
     gene            complement(27362..28639)
                     /locus_tag="IOD16_RS14605"
                     /old_locus_tag="IOD16_14610"
     CDS             complement(27362..28639)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018657.4"
                     /locus_tag="IOD16_RS14605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14610"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_201440492.1"
                     /transl_table=11
                     /translation="MTPPGRPLTGLEAGFFAYGSRPTPINLQIGGLVLFTGTPPGVDEG
                     RRFVLAWPDAVPALGLVPHFEGRRSRWLVRPELDPDRQGGVWEAPPGGLRAAVDSLMAE
                     EPPPDIPPWQCWLIRGYAEGEWAVLVKAHHALLDGASLVQLACRVLGGTSAEERRHRPR
                     RRGRAGDLVRVARGLLRYVLRFLPVATGAFAFEGTGARRFEWTTVPLATLRGVADRHGC
                     TVNDVFLAALTTVLREWPHTPWRRGPRPVWTLVPADLHERDGDDEPAAKVVNLRVALPC
                     HEPDARRRLRAVARATAISKRSGHIATGAAGSRALPVWLVSAILRLTFSRWHIDLLASN
                     VRGSRRALAYEGTPMTGMVPLGFIPRGHPLGAFLVSYSGQACIGFAVDPALPGGDALCR
                     LWEPAVQELDELDVVGTDREPEEALD"
     gene            complement(28636..29757)
                     /locus_tag="IOD16_RS14610"
                     /old_locus_tag="IOD16_14615"
     CDS             complement(28636..29757)
                     /NRPS_PKS="Domain: NAD_binding_4 (4-257). E-value: 4.8e-61.
                     Score: 198.0. Matches aSDomain:
                     nrpspksdomains_IOD16_RS14610_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013530.4"
                     /locus_tag="IOD16_RS14610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14615"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_201440493.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.8e-08, bitscore:
                     31.6, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 6.3e-59, bitscore:
                     198.0, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVALTGATGFLGTRLVRELLSRHEAITILTRAGGADPVDRIARA
                     LHAVGTPEPRLAERLRVVGIELSRPDLGLSAAAFRELADGLDAVWHCAGDIDLEANLSR
                     VRAVNVEGTRNVLALAAAGRRDPLFCYISTAFVAGGRRTGVVYEDDLDGSWGFENAYEQ
                     SKYEAELLVHSWATAHRRPAVVLRPSILVDDRPPRPELPAHPLQAVTRAIEAILKQATP
                     LDKVLLASAKGPIRLPGAPSAHLNLIPVDDAAAAMVELAQARRDRGVDTYHVVHHRDVT
                     VADVQHALRDLSRTRFTLVQEKPVRMTKLEAKLHAAMPSVTSGFLPYLAHRRRYDDTHV
                     RKVLGTSASTTPIGAGYLLSGLRDGSRPAGVAR"
     aSDomain        complement(28987..29745)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS14610_NAD_binding_4.1"
                     /evalue="4.80E-61"
                     /label="IOD16_RS14610_NAD_binding_4.1"
                     /locus_tag="IOD16_RS14610"
                     /protein_end="257"
                     /protein_start="4"
                     /score="198.0"
                     /tool="antismash"
                     /translation="LTGATGFLGTRLVRELLSRHEAITILTRAGGADPVDRIARALHAV
                     GTPEPRLAERLRVVGIELSRPDLGLSAAAFRELADGLDAVWHCAGDIDLEANLSRVRAV
                     NVEGTRNVLALAAAGRRDPLFCYISTAFVAGGRRTGVVYEDDLDGSWGFENAYEQSKYE
                     AELLVHSWATAHRRPAVVLRPSILVDDRPPRPELPAHPLQAVTRAIEAILKQATPLDKV
                     LLASAKGPIRLPGAPSAHLNLIPVDDAAAAM"
     gene            complement(29807..30630)
                     /locus_tag="IOD16_RS14615"
                     /old_locus_tag="IOD16_14620"
     CDS             complement(join(29807..30276,30276..30630))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611183.1"
                     /locus_tag="IOD16_RS14615"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="IOD16_14620"
                     /product="IS5 family transposase"
                     /protein_id="WP_201441368.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MARRRPWEVEDELWELIEPLLPKVERRFRYPGRRRLDDRKALCGI
                     LFVLYTGIQWEFLPQELGYGSGMTCWRRLRDWNAAGVWSRLHELLLARLQAAGALDWSR
                     AVVDSSSIRAVKGGPKTGPSPVDRARAGSKHHVITDGGGVPLAVTLTGANRNDITQLMP
                     LIHAVPPVRGRVGRPRRRPGRLFADRAYAHDKYRRQLRAQGIRPVIARRGVEHGSGLGV
                     HRWVVEQTLALLHWFRRLRVRWEIRDDIHEAFLSIACSIICWRRLQRHHSLR"
     gene            31105..31638
                     /locus_tag="IOD16_RS14620"
                     /old_locus_tag="IOD16_14625"
     CDS             31105..31638
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039694.3"
                     /locus_tag="IOD16_RS14620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14625"
                     /product="DUF6230 family protein"
                     /protein_id="WP_123741254.1"
                     /transl_table=11
                     /translation="MAVLVPAGLVSGAVLTGVAQGAIGVSLATAGQITLTVDRVESEGF
                     EIMPSVSTSGTAALVVRLPSAEVSGLCQTSTVDLPVIGAMTTELRARQVHVTDLVLEVH
                     DLGGALSLDELLVGRGADPDGGRVGHRAGKAVLGRMTIKAESVTARSFAAEGLQLGHRD
                     GTQGCSGSPSGDGR"
     gene            31635..32027
                     /locus_tag="IOD16_RS14625"
                     /old_locus_tag="IOD16_14630"
     CDS             31635..32027
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039352.3"
                     /locus_tag="IOD16_RS14625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14630"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_201440494.1"
                     /transl_table=11
                     /translation="MSRFGHWRRSCPFTAGVLAVAAAVELVVAVGLSAGVVVLSGSGAA
                     MAWLFAALLLVAGVTLLVNPALRHFAGVVALVVGVASLVHANLGGFLLGFAAAVVSGAL
                     ALSWVPVDDPTCEPEEPSSAVLPVEH"
     gene            complement(32817..33200)
                     /locus_tag="IOD16_RS14630"
                     /old_locus_tag="IOD16_14635"
     CDS             complement(32817..33200)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="IOD16_RS14630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14635"
                     /product="ATP-binding protein"
                     /protein_id="WP_201440495.1"
                     /transl_table=11
                     /translation="MDLPVSRTPSRELRRWVRAALYQEDEDCAEKAWLVLAELTANAHD
                     HGRSPAVVRVWGSTASSAVRIEVEDAGREAPGPGSSRWGGRRGFGLALVEGLAHRWGVD
                     VHPTGKTVWAELVGRSTGAEPVG"
     misc_feature    33329..33349
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.25"
                     /tool="antismash"
     gene            33417..33812
                     /locus_tag="IOD16_RS14635"
                     /old_locus_tag="IOD16_14640"
     CDS             33417..33812
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS14635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_14640"
                     /product="ATP-binding protein"
                     /protein_id="WP_201440496.1"
                     /transl_table=11
                     /translation="MNTVDLLRKSVDLDLPDSRPATAALMGLVAGLVGGVGDDRLVDVQ
                     VVAAQLVGNAYRHARAPRRLRMYRLPDRDLVRIEVGDGSSSLLPVLGRLDAPEHGRGLL
                     MVNRLSVNWGHRRDGDRKAVWAEVSLV"
     gene            complement(34706..35464)
                     /locus_tag="IOD16_RS14640"
                     /old_locus_tag="IOD16_14645"
     CDS             complement(34706..35464)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024583.4"
                     /locus_tag="IOD16_RS14640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14645"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_201440497.1"
                     /transl_table=11
                     /translation="MTRDQDVSVRTLASELARMGRLVEDEEHEEVARRFVEHLVHAVPD
                     CDLALLAVDRGGEVDVAAATGHPPLDLAADQGDPVREALRYREPRRLGDTTQDRRWPLF
                     AARLAVHGHRSCLVLPLPTLHSPTAAAMLVSREPHRFNDHSYDIILLIALHAGVALDNV
                     EVLHHSKQMVRHLTTALDTRHTIGLAQGLLMRHFAHDTEQSFTLLRRASQHTNRKLRDI
                     AHDLVTAHECGDFDEVLARHRIPGPDGVPM"
     misc_feature    complement(36139..36154)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            complement(36177..37214)
                     /locus_tag="IOD16_RS14645"
                     /old_locus_tag="IOD16_14650"
     CDS             complement(36177..37214)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /locus_tag="IOD16_RS14645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14650"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_201440498.1"
                     /transl_table=11
                     /translation="MRVTLKDIARAAGVSIMTVSNVINGKHARVSTDTVERVRRIVAEL
                     GYVPNGSARSLAANSSRLVGLLVPAASEASLAISPHNIAIVGHIERRLRKSGYHLLLRG
                     VSDTDEIGEALRSWSLDGAVLLGFLDEEVDRLDRRVTGATPVLAIDSYSDNPLTTGVRT
                     DDFTGAHLATSHLLSLGHRRIVFAAPSFTEVGVVHERFLGFRAALRDAGASPENCPIET
                     VDTTHDDGVELGRRLLTSHPEATAVFATADILAIGIIEGMRDTGVPVPQRVSVVGFDDL
                     DISAYITPTLTTVAQDIVGKATHAVDRLLDLARGGGHHTAPLVLDVRLVVRNSTASPRP
                     TAAGH"
     gene            37388..39007
                     /locus_tag="IOD16_RS14650"
                     /old_locus_tag="IOD16_14655"
     CDS             37388..39007
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077635.1"
                     /locus_tag="IOD16_RS14650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14655"
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="WP_201441369.1"
                     /sec_met_domain="Alpha-amylase (E-value: 2.2e-64, bitscore:
                     216.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSPAGHRQWWRDAVIYQIYPRSFADSDGNGTGDLNGVRGRLAYL
                     RDLGVDAIWFTPWYASPLADGGYDVADYRAIDPAFGTLADAEALIAEAAGMGIRTIVDV
                     VPNHVSSEHEWFKAALAAGPGSPERERFWFREGRGADGGLPPTDWVSSFAGGTWTRVPD
                     GQWYLHLFAPEQPDLNWNHPDVRREHEDVLRFWFDRGVAGIRVDSASMPVKDPALPEVR
                     QTYEPGGHPFIDRDELHDIYRGWRAVADSYDEPRVLVGEIWLDDQQRFARYLRPDEMHS
                     AFNFDFMGRPWEAKQLRESIQSTLDAHAPVGAPPTWVLSNHDVTRPVTRYGREDSSFSF
                     ATKRFGTPTDLELGERRARAAALLTAALPGALYVYQGDELGLPEVEDLPLEALQDPMHF
                     RSGGTDPGRDGCRVPLPWTRSGHSFGFSPDGSGAPAWLPQPAFGWGERSVEAQDRDPRS
                     TLALYRAALALRRSEPGLRGERFSWSDSTEDVLAFTRDDVVCVVNLGTAPVPLPDHHEV
                     LLTSVDLDGDHLPADAAAWLRA"
     gene            39027..40409
                     /locus_tag="IOD16_RS14655"
                     /old_locus_tag="IOD16_14660"
     CDS             39027..40409
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013697.4"
                     /locus_tag="IOD16_RS14655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14660"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_201440499.1"
                     /transl_table=11
                     /translation="MKSSAARPLLTRLATAAIVLPLVLTACGSDPDDQVGADGKVVITV
                     AMDSGLEKAAIDAFTKRAEQFEAANADVDVRTQEYTWTAASFTAQLAGGTIPDVFTVPF
                     TDGRGLIERKQIADVSEQVAKLPYSSSLNPNIAKAGQAADGRQWAVPIAAYGQALHYNR
                     TLFTQAGLDPDKPPTTWAEVRSAAKQITERTGQTGYAQMTSGNTGGWILTTLDYAFGGR
                     IEKITGDQAEATVDTPEMTEVLDTVRAMRWEDNSMGANFLYDWAGINQDFAAGRIGMYV
                     SGGGNYGNLVTQNGLKAADYGVAALPLADEPDAGVLGGGTLAVVSPKIGERSKEAAVKW
                     IDFYYMGKLTDQEAAVADAKTLAETNQPVGVPALPVVDRATYDKQQEWTKQYVNVPLDQ
                     MTPYTAKMFDQPLVTEPTRSTQDVYKILDRTVQALLTDQAADVPALLAEADAEVQAQIG
                     RG"
     gene            40519..41379
                     /locus_tag="IOD16_RS14660"
                     /old_locus_tag="IOD16_14665"
     CDS             40519..41379
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666445.1"
                     /locus_tag="IOD16_RS14660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14665"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_236594983.1"
                     /transl_table=11
                     /translation="MSTLVFLLPLLLVFGVFSWAPIVQSVVMSFQRTNLVGPVEFVGLD
                     NFAQVLSDPLLWTALRNTVWFAVLALLFGYPLPLLAAVLISEVRHRKGLFSALAYLPVV
                     IPPVVAVLLWKFFYDAGPTGVFNTVLGWVGLGPWQWLQNPGSAMPALVLEATWAAAGGT
                     VIIYLAALAGVPADLYEAAEIDGSGIWRKVWHVTLPRLRGVLLVTFILQIIGTAQVFLE
                     PFLFTGGGPANSTTTLLLLIYDYAFANSLGGDYGAATALSIMLAAVLALFSTAYFRLTR
                     SWSAS"
     gene            41376..42236
                     /locus_tag="IOD16_RS14665"
                     /old_locus_tag="IOD16_14670"
     CDS             41376..42236
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.4"
                     /locus_tag="IOD16_RS14665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14670"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_201440500.1"
                     /transl_table=11
                     /translation="MNRGLVSPTEWATTRTRLVLRTLQGLLLGTLLLVGLGPVLWLAKA
                     AVTPTQDTLRAPLSVFPHGFDLSNLVTAWTRVEIDKYFLNTVWLAAGSWAVQLVVATTA
                     GYALAVLRPRYGALITGVVLGTLFVPSIVLLVPLYLTVVDTGMINTFWAVWLPAGASAF
                     NVVLVQRFFASLPREVFEAARVDGAGPFRIFWSVVLPLSRPVIGVVSVFAVVASWKDFL
                     WPMLVLPDPAVQPLSVRLPALQRYVELDVFLAALAISSIIPIALFLVFQRLFLSGGALE
                     GAVKG"
     gene            42285..45263
                     /locus_tag="IOD16_RS14670"
                     /old_locus_tag="IOD16_14675"
     CDS             42285..45263
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028300.4"
                     /locus_tag="IOD16_RS14670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14675"
                     /product="CBM35 domain-containing protein"
                     /protein_id="WP_201440501.1"
                     /transl_table=11
                     /translation="MLSNLSRRGLAALTTTVVVAGLITLWSTAAPAAPAVLEAESAALS
                     GGARVESEHTGYSGAGYAGGFTDANRGNAKATFTTNATAGQNTLTLRYANGTGSTRTVT
                     LSVNGSVRQVSLPATPGWASWGTVRQSVPLNAAGNSIAVSYGAGDNGNVNLDNITVEPA
                     PVSAGDLEAESAQLSGGARVESEHAGYTGSGYVGGFTDVNRGAATATFTTAGGSAGSSE
                     LTLRYANGTGSTRSLSVSVNGAVRQVSLPATSSWAAWGTATAAVTLNAGANTIAISYGA
                     GDSGNVNLDNIRLSTAVPTTTTTTTTNPPGPAGTYELETGFLSGGAVVATSPSGATGTG
                     SVNLPGNGARVIRSINQTRAGNATVTLRHTNSSTRTVTLYVNGVKGAQLTLPGGTGWRT
                     TTHSAALRSGLNLIGYHVTSGDTGGVQLDNIAVTNTAGLAVRGATVPYTTYETESGTGT
                     RIAGRAYTTEAAEASGRSAMKLTGTGQYVQVTLTKPANAITVRAGLPDDASGNGTTAPL
                     AVYVGGTKVRDLALTSKYSWMYGDYPFTAGPGGARPHRYFDDARVLLPQTYPAGTVLRL
                     AKDTNATSYITVDLVEAEVVDGPTTAPAGYLSITDHGARADDGVDDSAALRSAVSAARG
                     NAARGVWIPAGRFTLSSLVQVNGVDVRGAGIWHTVLLGANRRGGFYVNGADTTLADFTF
                     DGDVTTRDPDGAPNSDAFIEGEFGTGSLIFNVAANHAKVGLWIKQADGLLASGMRIRNT
                     MADGLNINGNTANVRVEQSDFRNTGDDALTMWSWESAGTVSRSVFAFNTVALPILANGV
                     AIYGGTDNRAEDNLITDTVFNGSGVMLSTWHASMPFNGTTTVQRNTLTRTGTRNWDWHT
                     HTGAVWLFAERSDITGAVVLRDLEINDSNYHGLLLSWNKAVRDLTVANVRINGTGGATE
                     SFDDGAGTVTNANSHGTYFYLMSGTGRFDGVTVSGLKGTGSRGMVNDENRYTVQRGSGN
                     SGW"
     gene            45361..46953
                     /locus_tag="IOD16_RS14675"
                     /old_locus_tag="IOD16_14680"
     CDS             45361..46953
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950059.1"
                     /locus_tag="IOD16_RS14675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_14680"
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="WP_201440502.1"
                     /sec_met_domain="Alpha-amylase (E-value: 3.7e-68, bitscore:
                     229.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPWWQDAVFYQVYPRSFADSDGDGVGDLPGVRSRLAYLRALGVD
                     AVWLSPFYLSPQADGGYDVEDYRAVDPLFGTTDDARALLADAHALGLRVIVDVVPNHSS
                     SRHPWFREALAAPGSDHRARYHFRPGRDGGPPNDWQSLFGGPAWTRTTNPDGTPGDWYL
                     HLFSPEQPDFDWTHPAVAEEFRSVLRHWLDLGVDGFRVDVAHGLVKAPGLPDHGMPTHL
                     LDLTATPFWDQDGVHAIYREWRRLLDAYPGERVAVAEAWGPTLTRTARYVRPDELHQAF
                     NFHHLTCPWDPVALRAVIDDSLSAMSAVGAPATWVLSNHDVVRHATRLAPDADAGTGLR
                     RARAATLLMLALPGSAYLYQGEELGLPEVRDLPPHARRDPAFARTRGRDGFRDGCRIPL
                     PWWGTQPPYGFSPSDTRTWLPQPSHWGDYTVAAQTGDPASTLEMYRAALTARKTVRGEL
                     VWLPTASHVLAFERGTARCAVNLGDRTCTIDTGGVDHILTASGPVRHDGHLTSVPPDTT
                     IWWRTGTAGSGSL"
ORIGIN
        1 ttcgtgacct ccggcgtggc cgcggagtcc ttcccggcca acgccatcac cgccgagctg
       61 gtgccgatgc tcgacctgat gccgaagctg gacgccgtgg tgtgccacgc cggcggcgcc
      121 gtcaacgaag cgctcacctt cggggtcccg atggtcgtcg cgccggtgcg ggccgagcag
      181 gtggcgctgg cgcggcaggt cgcccggtcg ggcgcgggca tcgaggtgtc ggtcctcgac
      241 gtcacggtgg ccgagctgga cgccgcgctg cgggcggtgc tcgacgggcc ggaccaccgg
      301 cgccacgccc ggcggatcgg cgcggagttc gccgccgccg ggggagcggc gacggccgcc
      361 gcccacctgg tcgagttggc gtccggcacg tgaccacacg cgagcgggag gacggtccgg
      421 tggacgggtc cggggtgaag gcgctgccgg cggccgagga gttcgcgtgg gccaggcagc
      481 ggcgggccga catccgccgc gcgggtggcg tcctggacct ggtgctgccg ctgcgcgagg
      541 gcggcgccgg ccccgcgctg ttctgcgcgc cgccgctggt cggcgcgagc tggtgctacc
      601 tggcgctgct gccgcacctc gcgcccgagc acccggtgca cggcctccag ctgcgcgggc
      661 tgcgcaggcc cgaaccgctg ccggtcgacc tggccgaggc ggctcgggac ttcgccgacc
      721 agatcaggct cacccagccg cacggcccgt accacctgtt cggctggtcg atcggtggca
      781 acacggcgca cgcgatcgcc gaggagctgg agcggcgcgg ccacgaagtg ggcctgctcg
      841 tcatcggcga cacggtgccc ggcctgccga acagcctcag cgtggccgac gacaacctgt
      901 ggctggtgtg cgacttcgtg ctccgcgagc tcggctacca gccggtggtc gagccggacg
      961 accccgaccc ggtgcgccgg atgctggagg tcgtccgcgg ccggccgggg ttgggcctgc
     1021 acgagtggcc ggaccggcaa ctgctcgccc tgccgcacgt gatcaggaac aacctcgcgg
     1081 cggcacaacg ccacgtcccc ggtcgggtgc gcggcccggt gctgttcctc tccgccaccg
     1141 aggacgagcg gagcaccgag tcgaaggtgg cctcatggga cgatcacgtg agcacaccgg
     1201 tggacgtggt ggaggtggac tgcctgcacg agcacatgtt gctgcccgcg ccggtcgccc
     1261 ggatcggggc cgcgatctcc gcccgcctgg gcggcccgcg cgtgcccggg acgaacccga
     1321 agtcgcccga accgaccgca ggcgcactcg aaagcttcat tgccaccggg gaaccgcgaa
     1381 cctagtctct gcgtaggagt ccgcgtccgc ccttcgtccg gttcacgaga cctgcggtcg
     1441 gcgtagcagt cgacgggaca ccgcacgccg cccgaacccg cactgccgcc gatgcgcgaa
     1501 cccgccccgg tggcgacagt tcggcggtcc accgttctcc gcaaccggga ggtctcatga
     1561 gcggggcgaa cctgcgcacc gcgttggcgc aggacatgcg ggtcggcgcg ggcaacgtgc
     1621 tgcccatgct ggtggagcac ggcgcggacc cggacacgcc gcggatgacc ttcgacgtcg
     1681 acgtggacgg catccccgcg tggaccccgc tgtcgctgcg cgacctgacc gaacgggtcg
     1741 cggcacgggc ggactggttc gcccgcaagg ggatcggccg gcgcgacccc gtcgccgtgt
     1801 tcgtcacctc ggcggccgac gtgttcctca acttcttcgc gctcaaccac ctcggcgcga
     1861 tcccggcgct gatgaacggc gccatgccga tcgaggtcgc cgcggagttc gtccgccggc
     1921 tgcgcggcgt cggcgtgctg ctcgacgcgg accacgcggc gttgcgggac cacgaactcg
     1981 gcgtgcccgt cctcggtgac gcggcggaga ccggcaccgg cgacgccgac caggcgccgc
     2041 cgccctaccg ccaccacgac gacgacccgg tggcgatcac gcactcttcg ggcacgaccc
     2101 ggatgccgac gccggtcgtc cactcgcacc acagcctgtt cgccgccgtg cgcgcggtgc
     2161 ggctcaccga ggccaggccg cacggtcggg tgcgcgagct gtccgtgctg cccgccgcgc
     2221 acgcggccgg gatcatcgtg gtgaaccagg cgctgtgcaa cggctacgag ctgctgtgcc
     2281 tgtccgcgca gggcggcccg ttcgagcgca gcggcgaggt ggtgctggac gccatcgagc
     2341 ggtggcggcc gaccggcgtg ttcggcttcg ccgtcacgtg ggccgagctg gcccggttcg
     2401 acctgtcgaa gcgcgacctg ggctcggtgc gcaactggtc gagcaccggt gactgcgcgc
     2461 acgaggcgca catccggcgg ttggtcgcgg tcggcagcca cccggtctgg acgccggacg
     2521 gcgtggtgga cgagccgggc tcgaagttca tcgacacgct cggctcgacc gagatgggcc
     2581 acagcgcgtt cgccatcagc caccggcccg gcagcgaccg ctacgaccgg tgcgtcggca
     2641 agccgtaccc gttcgccgag gtggcgttgc tggacgtgac gacgggcgag gaggtgccgg
     2701 tcggccaggt cgggcagtgc gggctcaagt cgccgacgct cgcgcccggc tactggaacg
     2761 actcgaccgc cacctaccgc aaccgcctca acggctacta cctcaccggc gacctgatgt
     2821 accgggacga ggagggctac tactaccacc tcgaccgggc caacgacgcg gtcgacctcg
     2881 gcggcggcga gtggctctac accgcgttgt ccgaggagcg cgtcctggcc cggtgcccgg
     2941 acgtgcgcga ctgcacggtg ctcgcgtcga agcaggacga cggcgccccg gtgaccgacg
     3001 tgctgctggt gctgcacgaa ggggccgatc cggggctgga ccggggcgag gcggtgcggg
     3061 ccgcgctcgg cgaggcggtg gcgcgcacgg tgcggcgggt cgacgtggtg cccgacgagc
     3121 agctgaccgt cgggccgacc gggaaggtcc gcaagttcct catgcggcaa cgggtcctgg
     3181 cggacgcgcc acacgggagg tagctcgtgc ggtacccgct gtcgttcgag caggagtggg
     3241 cgctgtcccg gcccgcggtc ctgtcccacg cgacctggct ggacggtccg gtcgaccccg
     3301 ccgcgctgcg gcgggcggtg gacgtcgtgg tcgcgcggca cccggtgctc cggacgcacg
     3361 tcaccgcctc gggggagcag gtcgtctcgg agacgggtcg tgtggtgctg gagcacgtcg
     3421 tgctgcccgg cgacgtggcg cgcgccgagt cggtcgccgc ggagctggcc gagcggccgt
     3481 tcgacctgtc gcgcgagccc ctgacgaggg ccgcggtgat cgaggtcggt gcgggccggt
     3541 ggttgttcgc gctggtggcg caccgggtcg tggccgacgg ctccacgttg gcgatgctgc
     3601 tcgccgatct gtccactgtg taccgcgaag gcctgtccga gcttccgtcg tcgtggatgg
     3661 actacgggga ctacgccgtg tggcagcgcg agcggttgcg cggtgaggag ctggcacgtc
     3721 agctggcgca ctggcgcgag gtgctgcgcg acgcgcccgc gccggtgcgg ctcccggccg
     3781 ggcgtcgggc cgcgtcgctg accgcggtgg tcgacccgac cgcggtccgg cggctggcgg
     3841 ccgtggcgga gggggccggc gcgaccctgc ccgcggcgtt cctcgccgcg tacgccgtgg
     3901 tgctgtcccg gtacgcgggt cggcccgatg tcgtggtcgg ggcgccggtg agcggccgca
     3961 cccgggtgga gctggagccg atcgcgggtc cgttcgccga cgtggtcccg gtccgggttc
     4021 cgctggcggg cgagccgtcc ttcgccgagc tgctcgtccg ggtgcgggac gccgcggcac
     4081 aggcggtgtc gcacgacgag gttccgctcg gggtgctcgt ggaggaactg ggggtcggcc
     4141 tgtccgacgc ggtgcggttc accttcccgc cgcctgccgc gcccgcgctg gaccttcccg
     4201 gtgtgaccgt gcggagccgg gtcgccctga gcgacgcggc caccgccgat ctcgacttgc
     4261 gggtggacga gcacggcgcc ctgaccctgg agcaccgcac cgaccagggg ttcgccgact
     4321 gggtgctgcg gtcggtggtg gcggtgctgg agcacgcgac cgcggacagc gcggtgtcgg
     4381 agctgccggt gccggttccc gaggacacgt ggtccgcggt ggccgagcca tcgccggccg
     4441 agccgtcgcc caacggcgcg gtgcggtccg ctgccgcggg ggccgcggag cccgaggtgg
     4501 acgtgagtcc ggtgccggcg cggggtgaga tcgagcaggc catggccaag acctgggccg
     4561 acctgctccg ccggcccggc cgggtcggtg tgcgcgacaa cctgttcggc ctgggcgggg
     4621 gatcgctcgc ggcggtccgg ttcgcctcgc tcgtcgccga cacctacggc gtcaccctgc
     4681 ccctcccgct catcttcgcc tcgccgaccg tcgcggcgct cgcggagttc gtgtcggcgg
     4741 agttggaggc cgcccggacg gcccgggagg ccgaagccga ccaggcggcc cggttggcga
     4801 cgttgtccga cgacgagctg gacgacctgc tgcgcgccgt cgtggccacc cgcgagcgcc
     4861 gccgctccac cgggggtgac ggaaggtgag caccacgccc gccaccgccg gggacctcgc
     4921 cgacctggac accggcacgc tgttcggcgc gctggaggat cccgccctga actcgatgaa
     4981 cttcctcaac gaggtggcga tccactatcc ggacgcgata ccgctggccg ccgggaggcc
     5041 gagcgaggag ttcttcgaac tggaggacgt gcaccgatat ctgcgcatct tctccgagca
     5101 cctcggccgg cgcctgaccg aggcccaggt gcggcgcacc gtattgcagt acggccggac
     5161 caagggaatc atccacgaac tggtcgcgga aaacctccga ctggacgagg acatctcggt
     5221 cgacccggaa tcggtcgtgg tcaccgccgg gtgtcaggaa gcgatgttcc tcgtcttgcg
     5281 cgcgttgcgc gccgacgacc gcgacgtgct gctcgcggtg tcgccgacgt acgtcgggct
     5341 gaccggcgcg gcccggttgg tcgacctgcc cgtgcgcccg gtccgcaccg gggagcacgg
     5401 gatcgacctg gcggacctgg tcgcggtgat ccgccgggag cgcgccgccg gccgccggcc
     5461 gcgagcctgc tacgtcgtcc cggacttcgc caacccgtcc ggcctgagcc tggacctggc
     5521 gacccggcgg cggctgctgg aggtcgcggc ggccgaggac gtcctgctga tcgaggacaa
     5581 cccctacggg ctgttccacg gcgacgcgga ccgggtgccg acgctcaagg ccctggacgc
     5641 ggcgcggcgc gtcgtctacc tgggttcgtt cgccaagtcc gtgctgcccg gcgcacgcgt
     5701 cggctacgtg gtcgccgacc agcgggtatc cggcgccgac ggcacgaccg gcctgttcgc
     5761 cgaccagctt tcgaagatca agagcatgct gacggtgaac acgtcgccga tcgcgcaggc
     5821 cgtcgtcggc ggcaagctgc tggcgcacgg ctgccgcctc gccggcgcga ccgcacccga
     5881 acggcggctc tacgaccgga acctgcggcg cctcgtgacc gggctggcgg agcgcttccc
     5941 acccggctcg gacgtcacct ggaccgtgcc gaccggcggg ttcttcgtcg tggtcacggt
     6001 cccgttcgcg gtcgacgacc ggctgctgga acgctccgcc cgcgactacg gcgtgctgtg
     6061 gacgccgatg gggcacttct acgacggcgt cacggccgtt cgggcgctgc gcctgtcgtg
     6121 cagcgccgtt tccgtcgacc agatcgatcg cggcctcgac cggctggccg cattgatcaa
     6181 tgaccggtcg ggccggtcgg cgggcacgat cgaccacggc cacttggccg atagtgctcg
     6241 cggtgaaccg tgacgtacta ttccatgcgc tcgtcggcgg acgtgacgga aaactcctgc
     6301 gtaaatattt cgagaattgc gcgaccaggc ggggagacct gatgacaaaa ggcctggcgt
     6361 cgtccgggtt cgaactcgtg acgagtccgg aatgggtgga cgagatcctg ctccgcggcg
     6421 cggacgacga tatctgcctg tattcgggcg gaccggtcga ccggggtgcg ctgcgccgga
     6481 tggtcgcgga cgcgcaggca cgtctcgcgg cggccggact gggcccgggc ggttcgctcg
     6541 cgctgcggct gccgccgtcg acggcgtacg tggcgaacct gctcgccggc tggcgcctcg
     6601 gcgcccaggt gagcctcctc gaccaccgcc tcaccgccta cgaggtcgag ctggcgctcg
     6661 gcaggctcgc accgcaggtg gtggtcgagc cgggacgcgt cacgagcagc ccgctcagcg
     6721 cgttcgccga ggtggaggag accgtcacgg cccgctccgg ccggcccgcc gggacaccgc
     6781 acgcggtgat ccagttcagc tccgggtcca ccggtccgtc caaggtgatc ggccgcacgg
     6841 ccgccgacct ggtcgccgag atcgagcggt acacccggat cgacggcgtg ccgctgccgg
     6901 gcgagcggat cgtggtgctg gcctccatgg tgcacgtgct gggcctggtc ggcgccctgc
     6961 tgtacggcct gcacgccggc gtgcagatca ggccgcccga ccggctcacc ggcgacagcg
     7021 tgctggacgc ggtcgcggcc gaaccgaccc cggccacggt gctgggcgtc ccgttccaca
     7081 tcggactgct cgcgtccgtg gtggagccgc cgtcgctgcc gcagctgaag cggatgacca
     7141 ccggcggcga accggtgccc gccgcgaccg ccgccgcgtt caccgggaag tacggcgtgc
     7201 cgctgggcaa catgtggggc atgaccgagg tcggtgtgat cgccaccgac ctgttcggcg
     7261 agcaccggcc cgctctcacc ccggcgcccg gcctgtcggt cgtcgagcgc gacggcgagc
     7321 tgctggtgag ccggccggag tcgccgtacg tcggcctgtc cgacccggac cggtgggcgg
     7381 acggctggct gcgcaccagg gacgcgggcg cggtcgaccc ggacaccggc ctcgtcaccg
     7441 tcaagggacg gctggactct caggtgtcgg tcggcggcct gaaggtcgac ctgaccgagg
     7501 tggaggccac ggtggccgga ctgccgggcg tggtggcggc cgtcgtgctg cacgacgacg
     7561 tcatcaccgc ctacgcgcag ctcgacgcgc ccgccacggc ggcgtccgtc caggcgggcc
     7621 tggccgagcg gctcgccgcc tacaagagac cacgccggct gcacgtgctc gacgcgatgc
     7681 cgcgcaccat cacgggaaag ctggtccgcg accggtcggt gctccgccag gccgcgtccg
     7741 gagggatgtg atccgatgag aacacgaacc gtcgccgcac ccgggagcgg ggtgccgcgg
     7801 tgagccagga agagacaccc ggccgggacg acgtcctgcg gatgctggcg agcctcgacg
     7861 gcaggccgtc cgaggacgtc cccgagctga tcgaatcgat ggaactggcc tggctggtgc
     7921 accaggtgga acagcgctac ggcgtgcgca tggaactcga cagcggccag tacagccgca
     7981 tgaccaccgt ctccggagcc gctgacgtgc tccgggaagt gatcgggatg cctgatgaac
     8041 atatccggga ttgaccacat cgagttatac gtcggcgacg cgaagcagac ggcgttctac
     8101 ctgtgcagcg ccttcgggtt cgaggtctgc ggccagggcg gccccgagac ggggctggcc
     8161 ggccagcgct cgctgctgct gcggcagggt gacatccagg tcgtgctgac gaccggcctg
     8221 gtgcccgacc accccgcgac cgagtacgtg cgacggcacg gcgacggcgt ggccgtggtc
     8281 gggatcgggg tggacgacgt cgcggccgcc taccgcaccc tcaccgagcg gggcgccgaa
     8341 ccggtgtcac cgccccgtga gtacgcgtcc gcggctgccg ggggcgacga ccggcgggtc
     8401 gtcgtcgccg aggtctccgg cttctccgac gtgacgcacc ggctggtcga gcggcacggc
     8461 tcgccgcgcg agttcctgcc cggcgcgatc gaggtggccg aaccccaccc ggacaccgac
     8521 gtcaagctgc tgcgcgcgat cgaccacctg gcgatctgcg tgccggccgg cggcctcgcc
     8581 tcgaccgcgc gctactacgt ggacgtcttc gggttcgagc agatcttcga ggagtacgtc
     8641 gaggtgggcg ggcagggcat ggactccagg gtcgtgcaga gcccgtccgg tcacgtcacc
     8701 ttcacgctga tcgagccgga cccggaacgc cagccggggc agatcgacaa cttcctgacg
     8761 tggcacgccg gcgcgggcgt gcagcacgtc gcgttcggca ccgacgacat cgtcaaggcg
     8821 gtgggcaccc tcggcgacaa gggcgtgcgg ttcctcggca cgccgggttc ctactacgac
     8881 acgctcgagg agcgggtcgg tcacctggac gcgccgctgg acgagctgcg ccgcctcggc
     8941 gtcctggtcg accgggacca ctggggccag ttgctgcaga tcttcaccga gtcgatgcac
     9001 gtgcgccgga cgctcttcct ggagatcatc gagcggcggg gcgcgttgac cttcggcagc
     9061 gggaacatca aggcgctgta cgaggcgaag cagggcgagc tgtccggcac gacggccccg
     9121 tgaagggaac cacggtgaac gagttcacgc tgaccgacca cgaacgcgcg ctgctcccgt
     9181 ccgacgacga cgtccggttc ttcgccgagc acggctggta cctgtcgaag aagctgttct
     9241 ccgacgacga ggtggacgag ctgaccgcgg ccgtcggccg ctactactcc ggtgagcgga
     9301 gcaggcggct gccgacgcgc ccgccccggc tggcctactg gacgcccgag cacggcgatg
     9361 tccagcgcca caacgactac gtgcactacg agagcgacgg catcgccaag gcgctgctca
     9421 agccgctgat cggcgcggtg gccgcgcggc tggcggaggc cgacgagatc cgggtgttcc
     9481 agtcgaccct gatctacaag ccgccgatcg ccgaggagcc gtcgaacgtc gtgccctggc
     9541 acttcgacaa gcactactgg tcgtcgtcct cgtcggaccg gatgctcacc gcgttcatcc
     9601 cgttccacga ctgcgacgag gagctgggca cgatcaccat ggtcgacggc agccacctct
     9661 gggaggaggt cggctcggac gacagcgcca cgaagcactt cgccgagcgc gacgccgacc
     9721 acctggagaa cctgctcacc gccaacgccg agcacaacgg caccacggtc cggaagatcc
     9781 cgatgatcat ccccaagggg cacatgagct tccaccactg ccggacctac cacggcagcg
     9841 ggcccaaccg ctccacccgg ccgcgccagg ccatctcgct gcacctgcag gacggcgaca
     9901 acgcctaccg cgagttcccc ctgtcggacg gcaacctggc cttctacaac cacgactccc
     9961 tcgtgcggcg caccgcggac ggcaggccgg actacgccga cccggagttc tgcccgcccg
    10021 tgtggcgctc ctgaccgccg tggcggcaca cgcgccggac tccgacgtcg gcctgtaccg
    10081 cacggtgcgg ctgatccgcc ggttcgagga gcgggcggtc gaactcgtgc gctccggcga
    10141 catcatcggc ggcatccacc cctacacggg ccaggaggcc gtcgccgccg gcgtgtgcgc
    10201 ggcgctgcgc gtggacgaca tgatcaccag cacccaccgc gggcacgggc acgtgctcgc
    10261 caagggcgcc gacccggccc ggacgctcgc cgagctggcc ggccgcgcca ccgggctgaa
    10321 ccgggggcgc ggcgggtcga tgcacgcggc ggacttcggg tcgggcatcc tcggcgcgaa
    10381 cgcgatcgtc ggtgcgaacg gcgcgatcac cgccggggcg gcctgggcgg cccggcagga
    10441 cggcggcgac caggtcgcgg tgagcttctt cggcgacggc gcggtcaacc agggcgtgct
    10501 gctggaggcc atgaacctgg ccgccctgtg gcggctgccg acgctgttcg tctgcgagaa
    10561 caacggctac gccaccaccc tgaccgtggc ggacgccgtc gcgggcacga tcaccgggcg
    10621 tggcgaggcg ttcgggatgc cgtcggtgac ggtggacggg atggacccgc gcgcggtgct
    10681 cgacgcggcg cgcgaagcgg tggaccgcgc ccgcgcgggc ggcgggccgt cgctggtcga
    10741 gtgcctgacc taccggttcg acgcgcacca cacctgggag cacaaggccc gggtccgcta
    10801 ccgcgacgac gacgaggtcc ggagtggacg ggagagggat ccggtggaaa tccagggcgc
    10861 gcggctgacc ggcgacgagc ggacgagcgt cgacgcggaa gtcgaggccg tcgtggacgc
    10921 ggccgtcgcg ttcgcgctcg acagccccca ccccgacccc gtcggcgcgc tcgaccacct
    10981 gtacgccacc gggatgcggg cgcgtccggg cggtggtggg tgatgccgtg gctgtcctac
    11041 cggaaggcgc tcaaccgggc gctcgtcgac gagctggccc gtgatccggc ggtgttcgtg
    11101 ctgggcgagg acgtccgggt cgcggtctcc aacgtgaccg cgggcctgct caagcggttc
    11161 gggcccgacc gggtgctgga cacgccgctg tcggagcagg cgttcacgag cttcgccacc
    11221 ggggcggcgt tgcgcgggcg gcgaccggtg atcgagttcc agatcccggc gctgctgtac
    11281 ctggcgttcg agcagatcgt caaccaggcg cacaagttct cgctgatgac cggtggccag
    11341 acccgcgtgc cggtgacgta cctggtgccc ggctccgggt cgaggacggg ctgggccggg
    11401 cagcactccg accacccgta cgccctgttc gcccacgccg gggtgaagac ggtggtgccg
    11461 gccacgcccg aggacgccta cggcctgctg gcgaccgcga tccgggacga cgacccggtg
    11521 gtggtgttcg caccggcggc ggcgctcgac gtccgcgtgg acgtcgacca cgacgggctg
    11581 gccccggtgc cgctcggtgt cggccgggtc caccgcgagg gcgaggacgt cacggtcgtc
    11641 gcggtcggcc acctcgtgca cgacgcggtg gcggtcgccg aggagctggc cggtgacgtc
    11701 tcggtcgagg tgttcgaccc gcgcacggtg taccccttcg actgggacgg gctggccgct
    11761 tcgctggcca agaccgggcg gctggtcgtg gtcgacgact ccaaccgcat gtgcggcatc
    11821 gcggccgagg tcctcgccac cgcggccgag gggtgcgacc tggtcgtgcc gcccgtccgg
    11881 gtgaccaggc cggacggcgc cgtggtgccg ttcgcccgcg ggctcgacct cgccgtgcaa
    11941 cccgatcgcg cccagctgac cgccgcgatc cggaaggtgc tcaagcagtg acgacggagg
    12001 cccgcatgcc actggacccg cagctcacga cggcgcccgg gaacacggcc tccccgccgc
    12061 tctacaccct ttcggtcgag gaggcgcggg cggccgacct cgccgccatc cgggcggcgg
    12121 cgggcgcggg cgagccggtg cgccacgtca ccgaccggcg cctccccgga ccgggcggcg
    12181 acctgccgat ccgggtctac cgcccggtgg acgcggccgg gcccctgccc accgtggtct
    12241 acttcttcgg cggcgggtgg gcgctgggca gcatcgacac ctccgacgag atctgccgcg
    12301 ccctggccaa cgcggtgccg tgccaggtga tcaccgtcgg ctaccggctc gcgcccgagc
    12361 acaagttccc cgccgccgtg gacgactgcc gcacggccgt cgcctggatc gccgcgaacg
    12421 cggccgagct cggcgtcgac cccgaccgcc tcgccgtggc gggcgacagc gccggcggca
    12481 acctcgcggc cgtggtgacc ctggaccgcg acgggccccc gttggccgct caggtgctgg
    12541 tctaccccaa caccgaccac cgcggcgaca ccgggtccat gcgcgagaac gacgatcccg
    12601 ccgcgttcaa ccgccgatcc gtcgcctggt actggggcca ctacctggcg aacccggacg
    12661 acggccgcga cccgcgggcc tcgcccctgc tcgccgagga cctgaccggg ctgccgccgg
    12721 cactggtcat caccgccgag cacgacccgc tgcgcgacga gggcgagcag tacgccgacc
    12781 ggctgcgcga ggccggcgtg cccgtggtcg ccacgcggta cctcgggacg gcgcacggct
    12841 tcttcgccat gtcgggcgtg gtggacgcgg cccgtgaggc gcgggccgag gtcgcggcgt
    12901 tcctgcgcgc gcacctcggt ccgtgacgcc cacgtcgccg acacggcgtc cgggaatccc
    12961 tgccagggcc ggttcggcac cgtgccaagt ggaatgactg ccagcgggaa cgcgcatagg
    13021 cgtcgggtgc ggcggagtct aggctcgcca ccgtgaggat cctcttctcc agcctcggct
    13081 tgtacgggca cacgttcccc ctgctgccgc tcgcggtcgc cgcgcgggag ctcggccacg
    13141 acgtcgacta cttcaccggc aagggcttcg cggacgtcct ggcctcacaa ggaatcgagc
    13201 acgtcgaggg cggcctgtcg ccgcgcaagg cgttcgagca ggcgatggcg gggaccaggc
    13261 ccgggacgcc gggcgacgtc gacgtcgagc gggtcgcgtt cacgttcgcc tcggtgctgc
    13321 cgcgcagctt cgccaccggg ctggcgccgg tcctcgccga gcgcaagccc gacctggtcg
    13381 tgcacgagtt cggcaacccc ggcgcgggcc tggccgcgaa ggccgcgggc gtgcccgcgc
    13441 tgtgccactc gtacggccgg atgtggcagg agcccgactt cgccgcgccc gcgcgcgact
    13501 acctcaccgc cctcggcgcg gagctgggag tcgaggtgcc ccggaccgac tcgatggcgc
    13561 tgggccaccc gtacctcgac atctgcccgc cttcggtgca gaacccggag ttcctggcct
    13621 cgtcggccca ccggatcccg ttgcggccgg tggcgttcgc cgcagcgggg gagttgccgt
    13681 cgtgggtcga ggagcaccgg gagcccctgg tgtacctgac gttgggcacg gcgttcagcc
    13741 aggcgacgtt gttgcgcacc gccgtcgacg gcctggcggt gctgggcgcg cgggtgctgg
    13801 tggccgccgg cccgaaggtc gatccgggga cgttgggcga actgcccgac aacgtcgtgg
    13861 tgctgccgtg ggtgccccag gccgacttgc tgccccacgc ggacctcgtg gtccaccacg
    13921 gcggcgcggg caccaccctg ggcacgttcg gcgcgggcgt gccgcagctc gtcctgcccc
    13981 aggcggccga ccagttcaac aacggcgtgg tggtgaccga ggccgggctg ggcgaccacc
    14041 tgcggcccga ggacgccacc gccgaggcga tcaccaccaa ggcccgccac ctgctcaccg
    14101 acgaggccgt acgcgccgca gcccacgcga tggccgccga ggtggccggc atgccgtcac
    14161 ctcacgacgt cgcccgcacc ctgcccgact acgcctgagc agaacccgcc ggccgccggg
    14221 tcggtggtcg tcgcggtccg ggtggtcatc gacggcgtcg tcgtcgggcg gggccggtgc
    14281 gtcgcgggcg gcgcgcggcg cgtcgaggtg tcgggctcga cgtcaccgtg ttcaggagca
    14341 gccggcacag tcggatcatc gggtggtcca ggcccagcgt cggcgatccg agcatcacga
    14401 cctgccacag cagtgcctcg gcggacggtg tgtcgccgtt gagcgccatg agggaggcga
    14461 ggtccagtcg cgtctgcagc gtggcgggat gggccaggcc gtgcacgcaa cactggatct
    14521 ccagcacgtc gcggagctcg gtctcggcag aggcggtgtc gcccagttcc gcccggagcg
    14581 cggcgaggtt ggcccggcag gtcaggatgc cggggtgctc gtcgcccaac gtcggccgcc
    14641 cgaggtcgag cacggcttcg tactcggcct tggcctcggt gttccggccg agtcggcgca
    14701 gggagtgccc gaggccgtgg cgtgcgctca gcgcgggttc cgagtgctcg ccggacttgc
    14761 gcgcctggat tcgcaggatc gaccggaact ccgccgccgc ggccgccggt ttctccaggt
    14821 cggccagcac ggtcgcgtag ccgtgccagg tggccagcgt gttggcgtgc tcctcgccga
    14881 agacgcggcg atgggcttcc agcgccgcgt ggaactccgt ctcggcttcg gctgaccgcc
    14941 ccagcgagta gagggcctgg gcgagggcgt gccggccggc cagcgtggcc tcgtgatccg
    15001 gtcccagttc ccgctgcgcg atctccgtcg tccgccggtg tgcctgctcg gcggcgggcc
    15061 agtcaccccg ctcggccagc ctgccggcga gcgcgtgccg ggtgcgcagc gtgtcggggt
    15121 ggtggtcgcc gagcacgcgt cgttgcacgt cgagcacttc cgtcagctcc gcctcggcct
    15181 ggtccggctg ccccggcagt gcgggcgtgc cgcggacgac ggcgaggtcc gtcctggtcg
    15241 cgagcgtgtc ggggtggtgc tcgcccaagg tctgccgccg gcagtcgagg atcacctgga
    15301 agtcgaccgc cgcctggtcg aggtcgtgaa cgtgccggcg gaagaaggcc gcctcgcgag
    15361 cggcggtgat cgcctgttcg accaggtccg gcgggacgtg gtcgaggtgt gcccggcaca
    15421 gctccagcgc cgcctcggcg tgggaggcca gcgcgtgccg gcgggaccac gcctcctgcg
    15481 tgatgagtgg tgtgcgagtg gccgcgtgca ccagcttgac gagagcgatg gcgtgctggt
    15541 ggacgtccgg ctcggcggcg gcgtgatggc ggttggtgtc gcggatgagg cggtgcagcg
    15601 tcagcgcctg tcggtcgggg aggtcggcgc ggtcgacgag gccgaggtcg aggaggacgc
    15661 gcagcagccg ggacacggtc tccggggtgg ttgccgccca cgtcggcacg gtggccagca
    15721 gggccgcgtc gagcacgtcc accgggatgg gcgcctggcc gaagaaggac agcaaccgca
    15781 gcagcggccg ggcccggggg tgaccgcggc gggccagcag gtcgagggac agctcccagg
    15841 tgcgggagat cagctcccgt tcgtcgcgtt cctcgtcgtg atcggccggt ggggcgtcca
    15901 gcacgtccac gcgggcgtcg agcgccgcct ggtagtcggc gaacgtccgg gggagctcgg
    15961 cgcccgggac gaggagcgcg tcggcgccgg cggcgaggta gctgccggcc agccgcaacg
    16021 ccaacggcag gccgccgagc cggtcgccga ggcgctgggc ctccgggagg ctgcccgccc
    16081 gcggtcccgc caggtccgtc agcacgaggc cggcgtccgc ggcgtcgata ccggtcagga
    16141 ggcgttggtc cgtgtgccgc ggccaggccc gcgggttgcc ctgccggctg gtgacgacca
    16201 ccaggccgtg gcccggctcg gggggacgca gccaacccgt gccctccgac aaccgacctc
    16261 cgcccgacaa cacgtcgggg tcgtcggcgt tgtcgaccac cagcacccac cggccgtcga
    16321 cggcgtcgag ggcgcgccac aacaggtcgg gcgcactggc ccggcccgac cacgccagct
    16381 ccaccgagac gggattcgcc ccggcctgca gcgccacctc tcgaagaccg tcggccagcg
    16441 tctgcgcgtt gtcggccgac acccaccaca ccggcacctg tcgatcggcg gcgtgccgcg
    16501 ccaaccacag tgcgagcgtg ctcttcccgt acccgcccgc gccgtgcagc accaccaggc
    16561 ggcccggcgg atcggccacc aggcccgcca agtcggccga gatgtcgtcc cggccgcgca
    16621 ggtgctcggg caggcgtccc cacggagctt ccaccgagac cagacccggc ccgtgccccg
    16681 gagacaggcg cacgtcgtag gtgtcgttgc ggatgtcgcg tccggcctgc tgaacgctgc
    16741 tccccgactg cgcccacgcc cactgcgacg gccgccgaac gtcgtccacg cacgccaccc
    16801 cctcgggatc gacatccgca tccatccaac caccgccatc cacgcggcgg acgagccgca
    16861 cgggccggtg cgggtccgac atcgatgacg tgcgcagggc tcaccgatca gaaatcctcc
    16921 gccacgtcgt cagttctgac gacccgtcac accggtggaa ggatcgacga ccatgaccga
    16981 cgagagcctg ccgagcgacg acgccacggt cgtcgcggcg gtccgctcgg gcgatacggc
    17041 gcggttcgcg ctgctcacgg agcgctaccg gcgtgagttg caggtgcact gctaccggat
    17101 gctcgcgaac tacgaggacg cccaggacct cacgcaggag acgttcctgc gggcgtggca
    17161 caagcgggag tctttcaggg gccacgccgc gctgcggacc tggctgtacc ggatcgcgac
    17221 gaacgcctgc ctggacttcc tggagaagcg cgacgaccgg acacccgtgc cgtccgagct
    17281 gccggactcc gaggtgccgc acctgcagcc ctaccccgac cggatgctcc ccgaagaccc
    17341 gcaggagtcg gtggtggcgc gggagacgat cgagctggcg ttcatcgtcg ccgtccagca
    17401 cctgccgccg cggcagcggg cggtgttcat cctgcgcgac gtcctgggct ggccggcgtc
    17461 gaacgccgcc gacgccctgg agctgaccgt cgcatcggtg accagcgcac tgcaacgggc
    17521 gcgcgtgacg atgcgcgcgc agctgcccga ccgccgcctc gactggcgcg gcaccgccac
    17581 ccacgagctg tcgagcgacg agcgcgacgt ggtgaggtcc tacatcgacg cccacgagcg
    17641 caacgacctc gacgggctga tgggactgct gcgcgacgac ctgcgcttcg cgatgctgcc
    17701 cgatccgggc accgtgacca ggacggcgaa ggacgcggtg gacggctggg tctccggtgg
    17761 gctcttcggg cccggccacg acgactggcg cggtgtcgcc acggcggtca accgcatgcc
    17821 cgccgccgtg ctgtacctcc gcacccccga cgacccgcgg caccggctgt tcgccgtcgc
    17881 ggtcctgcac gtcgtggacg ggaagatcgc ccggctcacc gggttcgacg ccgccgacaa
    17941 gccgtggctg gacctgcccc cgacgctgtg atcggacaca tcaccaccgg gacgggtcca
    18001 gtgccccggg cgcggtcgcc gaagtcaccg cgtgacgcga accccgctgc cccgccggca
    18061 ccgccggcgg ggcagcccgt gctcatcgcc tcgtctcgta ccgggtcagc accacaccgc
    18121 cggggaacgt ccgggtctgc accagggtga ggttcaccca gttgtccagg gccgtgaaga
    18181 acggcgtgcc gccgccgacc aggaccggcg cggtgaccag gacgtactcg tcgatcagac
    18241 cggcccgcat cgccgccgcg gcgagcgtgg cgccaccgat gtccatgggg ccgccgtcgt
    18301 cggccttgag ccgggtgatc tcggcgaccg cgtcgccggt gaccaggcgg gtgttccagt
    18361 cgaccgtgct gatcgtggag gagaacacga ccttcggcat gtcccgccag cggcgggcga
    18421 actcgatctc cgccggcgtg gcccccggcc gctggtcggc ggtcggccag tggggactca
    18481 tcgcctccca cagcttgcgc ccgtacagcg ccaggcccgt cgccccgacc cggtcggacc
    18541 accactggaa cagctcgtcg cccggtgacg agtccggtcc gtccccgccg ctccagccga
    18601 tgtcgtcgcc ggtcgcggcg atgtagccgt ccagggtcac gttcatggcg aagatcagtt
    18661 tccgcatcgt gccaacctcc cgtgaatcga tctcacccat acagacgggc ggggcgcgga
    18721 aagctgatcg gtgcccgatc cgcgtccacg ggcagccctc gcgtacccga ctcggcacgc
    18781 gtcggattcg ggcctcacca gcgggcacgg tatgtcccgg aggtgggatg tcccgggtcg
    18841 tcacgtggtc gggcaacacg tcgtcggccg acgcggcggc ggcgttcgag cggtgcgtcg
    18901 agcacgccgg cggcgggacg ttcgtcatgg ggcacgctca cctgcgcgat gacggccggc
    18961 tggtggtcgg ggcgatctcg ggcgacacca tcatgaagtg cggcgtcgac gagttcggcg
    19021 tcaggaccag caccacggat cccgcccgcc acccggtccg cgagacgggg ttcggccttc
    19081 ccctgtccac cggctacgac gaccggctcg ccgcgaccgt ggtcgggtac gcgggcgacg
    19141 acgtggtggc ggtgaacttc cgcatcccgg acggccgggt gatcccggcg cgggtgcggc
    19201 aaggcgtcta cctcctggga ctgcccgccg agacgaatca cgactacggc gacctcaccc
    19261 acgaggcctt cgacgcgacc ggagcggtga tccccggccg ttgagccgcg caattcggtg
    19321 aacgtgtcgg tcaggacttc gtcggcggcc tgcgtcctcc gcattcccgg gcagttccgc
    19381 caagggcgcg cgtttcggtc cgaccaagag cgcattgcgc aagtggcgcg gtgtcgaatt
    19441 gtcgagtgac cgggcggccg gtcggatggc gacttgccgc tcgcgatgag gaagcgctac
    19501 ctgcggccct gtcgtcgtca tccgatcagg gaatggccga cgcgctctcg aggcggcaga
    19561 atcggcgcct gcaaggcggt ggtgggcgcg gccgttttgc ttcgcctttg atccgcccgg
    19621 agggccgcag ggtgatccgt gctcctggca cacgcgtcga cgccgggcat ggcggcagcg
    19681 ttcgacggcg tcgcccggga gcctgtccgc gcggcctgcg tctgcgctgc gcctgcggcc
    19741 gagttctccc tcgacgatcc cctgcgggag cgatatcccg acatctcgag gaattcagtc
    19801 ggacgtgatt cggcgcgggt gctcgtcgtg cggattcggc gccgcggatt ccctgtgcgg
    19861 ggcacgtgac ggcggttacc gggtgcgctt gtccttcgtg tcgagtcgct gacgagtcat
    19921 acccgtccga gtggctgccg ccccgcgacc gcaccaggtc ggtcctgtct tgaaagccac
    19981 cgatacatgg agaacagcgc atgagtccga actgtccgac ggatgccgtg gcgatcgtcg
    20041 gcgcggcgtg ccggctaccc ggcggcatcg ccgacctcga ccagttgtgg accgccctgt
    20101 ccgaggggcg tgacctgatc ggggaggtcc ccgagggcag gttcgacccc gaccggttct
    20161 tcgacccgga cccgctgcgc ccgggcaaga gctactcgtt cgccggcggc ttcctgtccg
    20221 acgtcagggg gttcgacgcc gagtacttcg gcatctcccc gcgcgaggcg gcggcgatgg
    20281 acccgcagca gcggatgctg ctggagatgg gcaccgaggc cctggacgac gcgggcctgg
    20341 accggcggga gttggcgggg tccgacacgg ccgtgttcct cggtgtgtcg ggcgccggtt
    20401 acggtctcct ccagctgaac gacctgcgca ccgccgacgt gcactcgatg atcggcggca
    20461 cggcctcgat catccccaac cggctctcct acgccctcga cctgcgcggt cccagcatgg
    20521 tggtggacac cgcctgctcg tcggcgatgg tcgcgctgca ccaggcgtgc gaggcggtgc
    20581 gcagcgggcg cagcgcgctc gcgctcgccg gcggcatcaa cctcctgctc gaccccatga
    20641 ccttcgtggg gttctccaag gcgatgatgc tctcgccgac cttccgctgc cggtccttct
    20701 ccgccgacgc cgacgggtac gtgcgggccg agggcggcgg cctcgtggtg ctcaagcgcc
    20761 tgtccgacgc cctggccgac ggcgaccggg tgcacgccgt cctgctggcg accggcacca
    20821 acaccgacgg gcgcaccaac ggcctggcca tgcccagcgc gcacgcccag gccgacctgc
    20881 tgcgcgggat ctacgacggg ctcggggtcg acgcggacga cctggtgtac ctggaggcgc
    20941 acggcaccgg cacgcccgtc ggcgacccgg tcgagtgcac cgccctcggc gaggcgctgg
    21001 gccgccgtcg ccaggcgggt ccgctgccga tcggctccgt caagaccaac ctggggcacc
    21061 tggagagcgc gtccgggatg ccgggcctgt tcaaggcgat gctcgtgctc cgccacgggg
    21121 tggtgccgcc gtcgctgcac ggcgaacagc ccaacccgga gatcgacttc gccgggctcg
    21181 gactgcaccc ggtgtcacag ccgctgccgg tcggcccggg ggtcgtcggg gtcaacagct
    21241 tcgggttcgg cggcaccaac gcgcacgccg tcctcgcgcc cgcgcccgtg gccggcgacc
    21301 cgccccggac cccgggcggc gcgctgccgg taatggtctc ggcccgttcc ggcgaggcgc
    21361 tggtggcggc ggtgggccgg gtgcgggacc ggttcgccgc ggcttcggcg gaggagttct
    21421 acgacctcgc ctacacgacc tgcctgcgcc gcacccccga cgcccaccgg gtcgtcgtgg
    21481 tggccgccga tccggcggag gcggccgacc ggctcgacgc ggcgctgcgc ggtgaccacg
    21541 aggtcgccgc cgcgctcgac gtggcgacca cccgcgacgg ggtggcgttc gccttctccg
    21601 gcaacggctc gcagtggtac ggcatggggc gtgacctgct ggcgaccgaa ccggccttcc
    21661 gcgcggccgt gacggcggtg gacgcggcgc tggcacccca cctggggtgg tcggtggtcg
    21721 aggagctggc cgcggccgag gaccggctgc acgacaccgc cgtcgcccaa ccgctgttgt
    21781 tcgccgtcca atggggactg gtcgcgctgc tgcgcgagcg gggagtcgtg ccgtccgttg
    21841 tcctgggcca cagtgtcggc gaggtggccg ccgcctgcgt ggccggcgcg ctggacctgg
    21901 acaccgccgc gaaggtggtg gccgagcgca gcctcgccca ggcccggacc gccggcgccg
    21961 gtcgcatggc ggcggtcggc ctgtcccacg agcgggccga ggaggtgctt gccgagttcc
    22021 ccggccaact ggtgccggcg gcggtcaaca gcgcccagga cgtcacggtc gccggcgacg
    22081 cgggcgcggt gacccggttg gtggagaagc tgatcgcgaa cgacgtgttc gcccgggagc
    22141 tggacctgga ctacgcgttc cacagccccg cgatggaccc cgtcgaggac cgggtgcgca
    22201 ccggcctggc cggtgtgcgc tccgccgagc ccgagatccc gatgctgtcc accgtgaccg
    22261 ggatgccggt gcgggcgggg gagctggacg ccgactactg gtggcgcaac gtccggcagc
    22321 cggtgctgtt ccaccaggcc gcgtcggcgc tcgcggaaca gggcatcggc gtggtggtgg
    22381 agatcggccc gcacccggtg ctcaccggct acctgcgccg caccggcggt gaaccgctca
    22441 agacggtggc gaccctcaac cggggtggca ccgggcgggc gttggcggag cgggtggtcg
    22501 ccggtgtgtc ggccgcgggc ggcgccctgc ggtggagccg gtacttcccc gaccgcggcc
    22561 gggtctgcga cctccccacc tacccgtggc agcgcgagga gcactggaag ggcgtgcccg
    22621 aggcgtgggt gcgcaccagc ggcaccgggc gtctcgacca cccgctgctg ggggagcgga
    22681 tgcccgcgtt ggagccgatc tggttcgccg ccgtagagcc cgcccgcacg ccgtggatgg
    22741 ccgaccaccg cgtcggcggg tcggtcgtgg tgcccgcgac cgggtacgtc gagatggcgc
    22801 tggccgccgg ccgccgggtg ctgggcgacc gggtggaggt gaccggcctg gacatcaccc
    22861 gcgcgctggc gctgtcgtgg ctgccgacca tggacgtccg gacccaggtg tcgctgtccg
    22921 acgaggacgg cctgtttcgg gtggcctccc gccagggtga cgacggtgac tggactctgc
    22981 acgcccgggg ccgcgtccgc cgcctggtcg ccgacgcccc ggtggcgccc cgggagcccg
    23041 ccgaacccgc cgaccacgtg cccgccgccg agcactacac cgcctgcgac cgggccggca
    23101 tcagctacgg cccggcgttc cgggggctgc gcgagatccg cgtccgaccc ggcgaggcgt
    23161 gggcggacta cgagttcccg ctctcctgcg acgaccacga ggtccacccg gcgctgctgg
    23221 acctggctct tcaggcgggc atcccgctgc tgcggctcga cacgcccgac agccgggcat
    23281 acctaccgtc ctctgtggac cgtgtccgac ggtggcggca acccaccgcg cacgggcgca
    23341 tccgggtcca ggtccgctcc cacaccgcgc gcgaggcgtg ctgggacatc agcgtgctcg
    23401 acgccgacgg cgaggtggcc gtcgagctga ccgggtgccg gctccagtcg ttcggcgcgg
    23461 tgctgcgagc aggcgtccag cgactggaaa ccgtgctgcg cgccgccccg cgcccgggcg
    23521 agcaggtcgg gccgtggccg gtgccggcac tgcccccggt caccgtgacc cctgccccct
    23581 gccacgccgc cgtgcgcggc atggcgaccg aggccggggc ccggttcgcg gtggcggccg
    23641 tcgagtcgct gctgcccggc cgggtcgcct tcaccaccga cgacctgctg gccgccggcg
    23701 tgctgcccga gtaccggcgg ctggtcgacg tgctgctgcg ctcggcttcg gcacacggcc
    23761 gggtccgcgc cgacggtccg gtctggcacc tgatcgggtc ccccgacctg gaggggttcg
    23821 cccgccggca cgccgagttc cccgaggccg cggcgctcct ggccctgcac ctcgggtgcg
    23881 gcctgaacct cgtggacgtc ctgtgcggcc gggtggacct ggaggacctc gtgctcggcg
    23941 acaccgaggc caccgcctac ttccacgacc tcaaccccgt cgccgcgagc tacaacgaag
    24001 cggtccggga gtcggtgcgc gccatcgtgc aacgctggcc cgccgaccgt ccgctgcgcg
    24061 tcctggaggt cggcgcgggc accggcggca ccacggggtt cgtgctcccg gtgctgcccg
    24121 ccgaccgcac gcggtacgtg ttcagcgacg tgtccgccgg ttgcctcacc ggggcccgga
    24181 ccaggttcgg ctcctgggac ttcgtggagt accggacgtt cgacctggac acggacccgg
    24241 acccgcggga gttccccgac ggcgggttcg acctggtgat cgcggccaac gcgctgcacg
    24301 cggcgaccga cttgcgcgcc gccgtgggcc gtgtcgcgcg gctgctgtgc cccggcggac
    24361 gcctgatcgc cgtggagtcg cacgacgtgg cgatgctggc gctgacctcg gggctttcgc
    24421 gcggtttctg gtcctacagc gacgtctcgt cgcggccgga ctcgccgttg gtccctgtgg
    24481 ccgagtggcc ggagttgctg cgcaccggcg ggttcgaccg ggtcgacgtg gccgaggacg
    24541 gcgaacggac cgggttctcc gtcctgaccg ccgccgtcgg cgacaccgcc gccaccccca
    24601 ccgtgccgac gacgacggcg cggtgggtcg tcgtgctcga cgacccggag gaccgggaac
    24661 gcgcggacgc cgtcgtggcg gccctgcgcg gggcaggagc cgacaccacg gcggtgaccg
    24721 ccgacgtccc cgactgggag gcggtcctgg tcgacgccga cggtgtcgcc gtcgtgctcg
    24781 ggggcgcggc cggtgatgcc gcggaccgtg ccgtgcgcgc cgcggcggtc ctgcggggga
    24841 tcggcgccgc cgccacccgt cgcgacgacg ccgagccgtt gccgctgtgg gtggtggcgc
    24901 ggccctcggg agccctgccc gcccccgagt cgcccgacga cccggtggac gccgccacct
    24961 gggggaccgc ccggaccttg ggcaacgaga accgctccgt ggccgtgcgg cgcgtctcct
    25021 gggaccacgg cgacgacccc gccgcctccg ccgggcggct cgtcgccgaa ctgctcgacc
    25081 cctccgacga ggacgaggtc gtgctcaccg cgtcgggccg cttcgtcccc aggacggtgc
    25141 ccgcccgcac cccgacccgc gcggacgcgg cgtccgcgcg cctggtcgtc cgcgaaccga
    25201 gcctgttcta ccggctgacg tgggtcgagc aggaggtccc ggaacccggt gccgggcagg
    25261 tggtggtgcg ggtggcggcg gcggccctga actaccgcga catcatggtg gccacggggc
    25321 tgctgccccc ggccgcggag gcgggggcgg gcatcgactc ggcgtcgacg ctggggttgg
    25381 agttcgcggg cgtggtcacc gccgtcgggc cggacgtgtc cgccgtgcgg cccggcgacc
    25441 gggtcttcgg catggcgccc ggggcgttcg cctcgcacgt gctcacgcgg gtggagcagc
    25501 tcgccccggt gcccgacggc atgtcctgca ccgaggccgc cacgatgccg gtcgcctgga
    25561 tcaccgtgca ccacggcctg cgcgcgctgg cgcgactgcg ggcgggggag acggtgctgg
    25621 tgcacggcgc ggcgggcggc gtcgggatcg ccgcggtcgg gctggcccgc cggaccgggg
    25681 ccacggtgat cgccaccgcc ggctcggagc tcaagcgcga ctacctgcgc gcgatcgggg
    25741 tcgaccacgt cgtggactcc cgcagcgtga agttcgccga cgacgtcctg cggattaccg
    25801 gcgggcgcgg cgtggacatc gtgctcaact ccctcagcgg cgaggcactg gtccgcggct
    25861 tggaggtgct ggcgccgtgc ggcaggttcg tcgagatcgg caagcgggac atctaccagg
    25921 actcccggct ggccatgcga ccgctggccg acaacatcag cctgttcgcc gtcgacatcg
    25981 ccaacctggc ctcccacgac cgcgactggg ccgtgcggtg cgccgaggag gtgttcgccg
    26041 ccgtcaccgc gggggagtac acgcccctgc cgcaccgggt ctacccggtg acgcgcatcg
    26101 acgaagcctt caagctgatg cagcactccc gccacatcgg caaggtcgtc gtgtcgttcg
    26161 acgaggccgt gcccgtcgag cggacgcccg gccggctcgc gctcgaccct ggggcgacct
    26221 acctggtcgt cggggggttg agcgggttcg gcgcggcgac cgcgcgccgg ctggtcgacc
    26281 ggggcgcccg gcggctggtg ctggtcggcc ggcgcggccc ggcgacggag gaagcccggg
    26341 acctggtcga ggagctcacc gcccggggcg tccgggtgga cgcccacgcg gccgacgtga
    26401 ccgaccgctc ggccatggcg gcggtgctcg gctcgatccc cccggaccac ccgttgcgcg
    26461 gtgtcgtgca cgccgcgatg gtgctggacg accggccgct ggaagacttg gacgacaacg
    26521 cgttccacac cgcgttggac cccaagctgc gcggcgcgct cgtcctggac gacctgaccg
    26581 acgggctgga gctggacttc ttcgtcctgt actcctccgg cgccgcgctg gtcggcaact
    26641 tcaagcaggc caactacgtc gccggcaacc tgttcctgga ggcgctgacc agggcgcgcc
    26701 ggcggcgcgg gcggcccgcg ctggccgtgc agtggggagc gatcgccgac accgggtacg
    26761 tggcgcgcga ggcgatgggc gagcagttgg ccaagctcgg cctcgcaccg tgccactccg
    26821 accaggcgtt ggacgtcctg gaagacctgc tgtgcgtgcc ggaagccgac gtcgtggccg
    26881 tgggcgactt ccggttcgag caggccgccg cggtgctgtc ggcgtccgcc acgccgcggc
    26941 tggcggggct gctgcccgag gacggcggtg agagcgggca ggagctgcgc gacctcctgc
    27001 gccgcatcga cgacttcccc cgcgccgagg cgttgcagct gatcgaggac gtgctggtca
    27061 ccgagttggc cgcgatcatg cagaccacgc ccgaccgcgt cgaccgaacc aagacgctca
    27121 gcgaactggg cgtggactcg ttgatgggca tggaactgct ggtggtgctg cgccaccggt
    27181 tccagtacca ggtgtcaccc atggaactga tgcagaccgg cggtcggatc tcggcgatgg
    27241 ccgagccggc cctggaccac ctgatccgga tggccgcggc ggaacgcgcg ctctgaccct
    27301 gacgcggaag cgcccggcgg tgtggccgcc gggcgcttcc cgtcttcgac ttcccggttc
    27361 ctcagtcgag cgcttcctcc ggctcccggt cggtcccgac gacgtcgagt tcgtccagtt
    27421 cctgcacagc cggttcccac agccggcaca acgcgtcccc gccgggcagc gccgggtcga
    27481 cggcgaaccc gatgcaagcc tggccggagt acgacaccag gaacgccccg agggggtgcc
    27541 cgcgcgggat gaagcccagc ggcaccatcc ccgtcatggg cgtgccctcg taggccaacg
    27601 cccgccgcga cccgcgcacg ttgctggcga gcaggtcgat gtgccaccgc gagaacgtga
    27661 gccgcaggat ggcgctgacc aaccagaccg gcagcgcccg ggacccggcc gcccccgtgg
    27721 cgatgtggcc gctgcgcttg ctgatcgccg tcgcgcgggc caccgcccgc aaccggcggc
    27781 gggcatcggg ttcgtggcac ggcagcgcca ccctcaggtt gaccaccttg gccgccggct
    27841 cgtcgtcgcc gtcgcgctcg tgcaggtcgg cggggaccag cgtccagacc ggtcgcggac
    27901 cgcggcgcca cggcgtgtgc ggccactcgc gcaggacggt ggtcagcgcg gccaggaaca
    27961 cgtcgttcac cgtgcacccg tggcggtcgg ccaccccgcg caacgtcgcc agggggaccg
    28021 tggtccactc gaagcgccgc gcaccggtgc cctcgaaggc gaacgcaccg gtcgcgaccg
    28081 gcaggaaccg cagcacgtag cgcagcaggc cgcgagcgac gcggacgagg tcgcccgccc
    28141 gcccgcgccg ccgaggtcgg tgtcggcgct cctccgccga cgtgcccccc agcacccggc
    28201 aggcgagctg gaccagcgag gcgccgtcga gcagggcgtg gtgggccttc accagcacgg
    28261 cccactcacc ctcggcgtac ccccggatga gccagcactg ccacggcggg atgtccggcg
    28321 gcggctcctc ggccatgagg gagtccaccg cggcccgcaa cccgcccggc ggggcctccc
    28381 acaccccgcc ctgccgatcg gggtcgagct ccgggcggac cagccaccgc gaccgccgcc
    28441 cctcgaagtg cggcaccagc cccaacgcgg gcacggcgtc gggccaggcc agcacgaagc
    28501 gccgaccttc gtcgacgccg ggcggcgttc cggtgaacag gaccagcccc ccgatctgca
    28561 ggttgatcgg cgtcgggcgc gagccgtagg cgaagaagcc ggcctccaga ccggtgagcg
    28621 gcctgcccgg gggcgtcatc gggcgacccc ggcaggccgg gagccgtcgc gcagaccgga
    28681 caacaggtag ccggcgccga tcggcgtggt gcttgcggac gtgccgagca ccttgcgcac
    28741 gtgggtgtcg tcgtagcggc gccggtgcgc caggtagggc aggaaccccg acgtcacgga
    28801 cggcatggcc gcgtgcaact tggcttccag cttggtcatg cggacgggtt tctcctggac
    28861 gagggtgaaa cgggtgcggg agaggtcgcg cagcgcgtgc tggacgtcgg ccaccgtgac
    28921 gtcgcggtgg tggaccacgt ggtaggtgtc cacaccgcgg tcgcgtcggg cctgagccag
    28981 ctcgaccatg gccgccgccg cgtcgtcgac cgggatgagg ttcaggtggg cggagggcgc
    29041 gccgggcagg cggatcgggc ccttggccga ggccaggagc accttgtcga gcggggtggc
    29101 ctgcttcagg atcgcctcga tggcgcgggt gaccgcctgg agcgggtggg cgggcagctc
    29161 cggtcggggc ggacggtcgt cgaccaggat gctgggccgc agcacgacgg ccgggcggcg
    29221 gtgggcggtg gcccaggagt gcacgagcag ctcggcttcg tacttggact gctcgtaggc
    29281 gttctcgaag ccccaggagc cgtcgaggtc gtcctcgtac accaccccgg tgcggcgccc
    29341 accggccacg aaggcggtgc tgatgtagca gaacaagggg tcgcggcggc cggcggcggc
    29401 cagggcgagc acgttccggg tgccttcgac gttgaccgcg cgaacccggg agaggttcgc
    29461 ttccaggtcg atgtcgcccg cgcagtgcca cacggcgtcg aggccgtcgg ccagctcccg
    29521 gaaggcggcg gcggacagtc ccaggtcggg ccgggaaagc tcgatcccga cgacccgcag
    29581 gcgctccgcg aggcgcggtt cgggtgtgcc gacggcgtgc agcgcacgtg ctatccggtc
    29641 gaccgggtcg gcgccccccg cgcgggtgag gatcgtgatc gcctcgtgcc gggacagcag
    29701 ctcgcgcacg agccgggtac cgaggaaacc cgtggcaccg gtgagcgcaa cgcgcatggg
    29761 acagcctctc gtgaccttcg gttgaccgac tgcggactta gaactcctaa cgcaatgagt
    29821 ggtggcgttg gaggcgtcgc cagcagatga tcgagcaggc gatgctgagg aaggcctcgt
    29881 ggatgtcgtc gcggatctcc cagcggacgc gcaggcggcg gaaccagtgc agcagcgcga
    29941 gggtctgttc gaccacccag cggtggacgc ccagacccga gccgtgttcg acgccgcggc
    30001 gggcgatgac cggccggatg ccctgggcgc ggagttggcg gcggtacttg tcgtgggcgt
    30061 aggcccggtc ggcgaacaac cggccgggcc tacgccgcgg tcgtcccacc cgtccacgca
    30121 cgggcgggac ggcgtggatc agcggcatca actgggtgat gtcgttacgg ttcgcgccgg
    30181 tcaacgtcac cgccaagggc acgccgccgc cgtcggtgat cacgtggtgc ttggagcccg
    30241 cccgggcacg gtcgaccggg ctcggcccgg ttttgggccg cccttcaccg ccctgatcga
    30301 cgaggagtcc accaccgccc gagaccagtc caacgccccc gcggcctgca acctcgccaa
    30361 cagcagctcg tgcagccggg accacacccc tgcggcgttc cagtcccgca accgccgcca
    30421 acacgtcatg cccgacccgt agcccagctc ctggggcagg aactcccact ggatgcccgt
    30481 gtagagcacg aacaggatgc cgcacaacgc cttgcgatcg tccaaccgcc tacgaccggg
    30541 ataccggaac cgccgctcga ccttcggcaa cagcggttcg atcaactccc acagctcgtc
    30601 ctcgacctcc caaggccgac gccgggccac accaacctcc caccggacca acaccacatc
    30661 cgacaagatc acagcatacc caagatcatt ctgttaggag ttctaaatca ggacgatcaa
    30721 gcaccggcaa gctgcgcgcc accttcgagt gacacgccaa agggttacgg tgcagtactc
    30781 ctcgggctcc acgcccagtt ccagcgtgat cgccgagccc gacagtggac gcggatgcct
    30841 gtgaggcagg gatgtcacgt caccccgtgt gtgcacagtg gacagctcca cgactgggtg
    30901 tcccgctgac tcgtgcctgc gcaccgcggt caccgcaagt ggttgtcctt catgccaacg
    30961 gggaatggca cgtcatcctc cccgcccgtt aggttcggtg ccggcccgcg gcacccgggg
    31021 ccgttgtccc gtgctcgatt acctgagggg tctgatccgg tggatcgcgg tcgtagccga
    31081 gggcgcacga gctggaagcg tttcgtggcg gtgctggtgc cggccgggtt ggtgtcgggg
    31141 gcggtgctga ccggtgtcgc ccagggagcg atcggggtgt cgctggccac cgccggccag
    31201 atcaccctga cggtcgaccg ggtcgagtcg gaaggcttcg agatcatgcc ctcggtgtcc
    31261 acctccggga cggcggcgtt ggtggtgcgc ctgccctcgg cggaggtgtc ggggttgtgc
    31321 cagacctcga cggtcgacct gccggtgatc ggcgcgatga ccacggagct gcgggcgcgg
    31381 caggtgcacg tgaccgacct ggtgctggag gtgcacgacc tcggcggcgc gctcagcctc
    31441 gacgagttgc tggtcgggcg gggcgcggat ccggacggcg gccgggtcgg ccaccgcgcg
    31501 gggaaggcgg tcctgggccg catgaccatc aaggccgagt cggtgacggc acgctcgttc
    31561 gccgccgaag ggttgcagct gggccaccgc gacggcacgc aggggtgctc gggctcaccg
    31621 agcggcgacg ggcggtgagc cgcttcggcc actggcggcg ctcctgcccc ttcaccgccg
    31681 gggtgctcgc cgtcgcggcg gcggtggaac tggtcgtcgc cgtgggcctc tccgccgggg
    31741 tggtggtgct ctccggctcg ggcgcggcga tggcctggct gttcgcggcc ctgctgctgg
    31801 tcgcgggagt cacgctgctg gtcaacccgg ccctgcgcca cttcgcgggc gtcgtggccc
    31861 tcgtggtcgg cgtggcgagc ctggtgcacg ccaacctggg cggcttcctc ctgggcttcg
    31921 ctgcagccgt ggtgagcgga gcgctggcac tgtcgtgggt cccggtcgac gacccgacct
    31981 gcgagccgga ggagccgagc tccgccgtac ttccggtcga gcactgacac gccgatccct
    32041 tggctccggc gcatttcggg tggcggctcg tccgttgtgg tgatcgcggc cggcctggac
    32101 gacggtggcg ccctggaaca gtccgtccac ccacgggctg gtcaggatca ggacggtggt
    32161 gccgccggtg accacctccg cgcagcgcac ctgggccgcc accgccaccg ccaccgatgc
    32221 ccggtcccgg cggtgcccgc cggcctcgtg ccgcagcacc ggaaactccc atcccgggtg
    32281 cagcagtcgt aacccccaag cttcgcacca cgacgacgaa caccctcgtc cgcaccgcac
    32341 cgcaccgcac cgcaccgatc gcgtggagcg ctcgggcgtt gaccgccgcg ccggccaccc
    32401 tcgttcacgc accggtggaa ctctccgccg ttgagggtgt cctggcgaga tcggcgccgg
    32461 tggtggcgtc gttgccgtag atcgtcttgc cggggttggc gctggtgcag tcaatcgtgt
    32521 cgttcccgca gtgcgcacgg cgaggttcga cggcctgtgg gggtgcccgg acgctgcgcc
    32581 gaaccgtcga accgcggtgg tggtgcgccg tgcccgacag gcatgaacgt ggcgtctgcg
    32641 cgcgaccggc gtccggccgt cggctggacg gctctgctcg ggcggtcgtc gggccgacga
    32701 cctcgaaccg ccggtactgc gtcgaagcac tccacagccc gcgatcgggc cgggccgctg
    32761 gagccggtcg tggccaacgg ctcggaggac gggatcgcga caccggggcg ccggggtcag
    32821 cccaccggct cggccccggt tgaacggccg accagctcgg cccacacggt cttgcccgtc
    32881 gggtggacat cgacacccca tcggtgcgcc aagccctcga cgagggccag gccgaagccg
    32941 cgcctcccgc cccagcggga cgatcctggg ccgggcgcct cgcggcccgc gtcctcgacc
    33001 tcgatccgca ccgccgacga ggccgtcgac ccccagaccc tgaccacggc cggggaccgc
    33061 ccgtggtcgt gggcgttggc cgtcagctcc gcgaggacca accaggcctt ctccgcgcag
    33121 tcctcgtcct cctggtacaa cgccgcccgc acccaccgtc gcagctctcg tgacggcgtc
    33181 cgcgagaccg gcaggtccat gctcaacacc agccgaccct gttcgccccc gtgtccgtca
    33241 ccctgcgcct tgggaccaac ctgcccgatc gcactcattg cctcgaccta cccgggcagc
    33301 cccatctcca caccgacccc ggcggctcgt gtcgtcgtgg tgacgaccgg tccgtcggag
    33361 cgggtatagg gtgtcgtatc tgtgccttgt gaggccacag gcatcgaggg cgtgcagtga
    33421 acactgtcga tcttctccga aagagcgtcg atctcgacct gcccgacagt cgcccagcca
    33481 cagcagccct gatgggtttg gtcgccggcc tggtgggcgg ggtcggtgac gatcggctcg
    33541 tggacgtcca ggtcgtcgcc gcgcagttgg tcggcaacgc ctaccgtcat gcccgagcac
    33601 cgcggcggtt gcggatgtac cggttgcccg accgtgatct ggtgcggatc gaggtgggcg
    33661 acggcagctc gagcctgctg ccggttctgg gccggctgga cgcacccgag cacggccgcg
    33721 gcctgctcat ggtcaaccgg ctgtcggtca actggggaca tcggcgtgac ggtgaccgga
    33781 aagcggtctg ggccgaggtc agcttggtct gagccgttcg gccgcctgtc ttcaggccga
    33841 gcgcggtccg tcgtcgtggc acgaggtcgt ggcggcgtgt gcttgacgac gtcgaccacc
    33901 ggtgtccacg tcgacgggca tgggtggagc cggtggacgg atggggagtg agtcgacttc
    33961 cccaggccgg ctcgcccgcg cacggccgcg atgtggccgc cgctcgccgg gcgatgtgca
    34021 ccacgcccgg cgcgaatctc gccggctcgg ggccaaatcg ccggtcaagg cgttgaccag
    34081 gcgctcgccg aggtgccgga gatgcccagg cagcacgggc gctgtttgct caacgtctcc
    34141 gtgctgcctg ggcccggacc actggaagcg gccctaccgc cgtgcgatcg ctcgttcggc
    34201 actacgccaa ttacccggct tgcgcggacg tacaccgcag gtgcgggggt ttgtccggtg
    34261 accacggcga ccgctccgcc agcactgccc gccgttgcac ggcgggtgaa gcaggcaggg
    34321 ccgggacgtc gaccgccggt cgagcaacct ccggcagggc aacgggcgaa tctcgctggc
    34381 cgcccctcgg cgcgccgaat ccctccgccg gcacccagcc accggggcat cgcgttcgac
    34441 tccgggcgat ctgcgacgat gctggcccgg acgtcgagga atgggtattc gcgcaggtcg
    34501 cgtgcctgca ctcgaacacc tgctccgtgg tgatcagcac ctggttcgcg agcagtggcc
    34561 ggtcggatgg ccgtcctggg cggagaggtg gacgtgtcct gctccgcccc gcgtgctccg
    34621 cggccgaccg gtgaggatgc gccggtacgg acagcgcgtg cgcaccgccg gccggcacga
    34681 tcgccggcca cctgcgtcga tccggtcaca tcggcacgcc gtcaggtccg gggatgcggt
    34741 ggcgggccag tacctcgtcg aaatcgccgc actcgtgagc ggtcacgagg tcgtgggcga
    34801 tgtcgcgcag cttgcggttg gtgtgctgcg aagccctccg cagcagcgtg aagctctgct
    34861 cggtgtcgtg ggcgaagtgc ctcatcagca gaccttgcgc caggccgatg gtgtggcggg
    34921 tgtcgagcgc cgtggtcagg tgccgcacca tctgcttgct gtggtgcagc acctcgacgt
    34981 tgtccaaggc gacgccggcg tgcagggcga tcagcaggat gatgtcgtag gagtggtcgt
    35041 tgaaccggtg gggttcgcgc gacaccagca tcgcggcggc ggtgggggag tgcagggtgg
    35101 gcaggggcag caccaggcag ctccggtggc cgtgcacggc cagacgtgcg gcgaacaacg
    35161 gccagcggcg gtcctgcgtg gtgtcgccca gccggcgcgg ttcgcggtag cgcagtgcct
    35221 cgcgaaccgg gtcaccctgg tccgcggcga ggtcgagcgg cgggtgaccg gtggccgcgg
    35281 ccacgtcgac ctcgcccccg cggtcgaccg cgaggagcgc cagatcacag tccgggacgg
    35341 cgtggaccag gtgttcgacg aagcggcgtg cgacctcctc gtgctcctcg tcctccacca
    35401 acctgcccat ccgggccagc tcggaagcca atgtgcggac ggagacgtcc tggtcacgtg
    35461 tcatcggtgc acccctcgac aggccgcgct ccgcgcgacg gccgcgagac cgggcggagc
    35521 tggtaaccgg gatgctgcac tgctgaacac cctccaggcg gtcaagataa cgcaatgccc
    35581 cggccacacg ttcccccgac ctgccgcggc ggatgggcag ggcacgcgcc gaccgggagc
    35641 gcggacgccg tgccacctcg tgtcgttctc gtagccgtac gtgcgcggac gtgactcacg
    35701 gtggtctcgt cgtgttcggg catgtgggcg gtgtggttgg gaggagcccc gagtggtcgg
    35761 aggtcgctgc ggagcgcgtc gacttgcggg gcagcgctta cgaagaggtg ctgcgcaccc
    35821 agcggccgtg gcaggagcag gacggtgacg gcgcgcgggt cgtgctgccg gtgaccaacc
    35881 gcggcgaccg cgtcggcgag cagcgaggtg aggatcaccg acttcgtgca accaggggag
    35941 gatcgatccg taggcggtct gccatgagtc gtcacctcac ctgttaaaca cgcgccctgc
    36001 gacggtcgtg aagctcgtca accagcttct cggccgcttc ggggccgggt tcgtcctccg
    36061 atgcggcccg gtacctcgca ggagagacgc gctggtgaac gcttcaggct cgtctccgaa
    36121 catcgacgcc accacggcgt gacgcggtcg tgccaggtca tcggcggccg ccggtgtcag
    36181 tggcctgcgg ccgttggtct cggggatgcg gtggagttgc gcacgacgag tcggacgtcg
    36241 aggaccagcg gtgcggtgtg gtggcctccg cctcgggcga ggtcgaggag gcggtcgacg
    36301 gcgtgggtcg ccttcccgac gatgtcctgg gcgacggtgg tgagcgtggg ggtgatgtag
    36361 gcgctgatgt ccaggtcgtc gaacccgacg accgagaccc gttgcggcac gggaacgccg
    36421 gtgtcgcgca tgccctcgat gatgccgatc gcgaggatgt ccgcggtggc gaacaccgcg
    36481 gtcgcctcgg ggtggctcgt gagcaggcgc ctgcccagtt ccacaccgtc gtcgtgcgtg
    36541 gtgtcgacgg tctcgatcgg acagttctcc ggggaggccc cggcgtcccg cagggccgcg
    36601 cggaagccga ggaagcgttc gtggacgaca ccgacttcgg tgaacgacgg cgcggcgaac
    36661 acgatccgac gatgccccag ggacagcagg tgcgaggtgg ccaggtgtgc gccggtgaag
    36721 tcgtccgtcc gcaccccggt ggtcaacggg ttgtcggagt agctgtcgat ggccagcacc
    36781 ggtgtcgctc cggtgacccg gcggtccagg cggtcgacct cctcgtcgag gaagccgagc
    36841 agcacggctc cgtccaggct ccaggaccgc agggcctcgc cgatctcgtc ggtgtcggac
    36901 accccgcgca gcagcaggtg gtagccgctc ttgcgcagtc ggcgctcgat gtgaccgacg
    36961 atggcgatgt tgtgcgggga gatggcgagg ctggcctcgc tcgcggcggg cacgagcagc
    37021 ccgacgaggc gcgagctgtt ggcggccagg ctgcgtgcgg aaccgttggg cacgtagccg
    37081 agctcggcga cgatccggcg cacccgctcg acggtgtcgg tcgacacgcg agcgtgcttg
    37141 ccgttgatca cgttcgacac cgtcatgatg ctcacgcccg ccgccctggc gatgtccttc
    37201 agggtcaccc gcaccggtct gatctctcct ctcgcctccg cagaacacgg actggtcgtt
    37261 gacacctgcg ctgcggcgcg gttagtgtcc cacaccactt gatatagcgc taaaccgact
    37321 ctgaccggcg acgttcggtt catttggggt gcgccgtgag cggcaatgag ggggagagat
    37381 cgtgacgatg ggcagcccgg cggggcaccg gcagtggtgg cgggacgcgg tgatctacca
    37441 gatctacccg cgcagcttcg ccgactccga cggcaacggc accggcgacc tcaacggcgt
    37501 ccgcggcagg ctggcgtacc tgcgcgacct gggtgtggac gcgatctggt tcaccccgtg
    37561 gtacgcctcg ccgctggccg acggcggtta cgacgtggcc gactaccggg ccatcgaccc
    37621 ggcgttcggc acgctggccg acgccgaggc gctgatcgcc gaggccgccg ggatgggcat
    37681 ccgcacgatc gtcgacgtcg tcccgaacca cgtttccagt gagcacgagt ggttcaaggc
    37741 ggcgctggcg gccggacccg gttctccgga gcgggagcgc ttctggttcc gcgagggccg
    37801 cggcgcggac ggcgggctgc cgccgacgga ctgggtgtcg agcttcgcgg gcggcacgtg
    37861 gacgcgggtg ccggacggcc agtggtacct gcacctgttc gcccccgagc agcccgacct
    37921 gaactggaac cacccggacg tgcggcgcga gcacgaggac gtgctgcggt tctggttcga
    37981 ccgaggcgtg gcgggcatcc gggtcgactc ggcgtcgatg ccggtcaagg acccggcgct
    38041 gcccgaggtg cggcagacct acgaaccggg cgggcacccg ttcatcgacc gcgacgagct
    38101 gcacgacatc taccggggct ggcgcgcggt ggccgactcc tacgacgagc cgcgcgtcct
    38161 ggtgggggag atatggctgg acgaccagca gcgcttcgcc cgctacctgc gtcccgacga
    38221 gatgcactcg gcgttcaact tcgacttcat gggacgcccg tgggaggcca agcagctgcg
    38281 cgagtcgatc cagtccacct tggacgccca cgccccggtc ggcgcgccgc ccacgtgggt
    38341 gctgtccaac cacgacgtca cccgcccggt cacccggtac ggccgtgagg acagctcgtt
    38401 ctccttcgcc accaagcggt tcggcacacc gaccgacctg gagctgggag agcggcgagc
    38461 tcgcgcggcg gcgctgctga ccgcggcgct gcccggcgcg ctgtacgtct accagggtga
    38521 cgagctgggt ctgcccgagg tggaggacct accactggag gcgttgcagg accccatgca
    38581 cttccgctcc ggaggcaccg acccggggcg cgacgggtgc cgcgtgccgt tgccgtggac
    38641 ccgctcaggt cactcgttcg ggttcagccc ggacgggtcg ggcgcccctg cctggctgcc
    38701 gcagccggcc ttcgggtggg gcgagcgctc ggtggaggcg caggaccggg acccgcgttc
    38761 cacgctggcg ctctaccggg ccgccctggc cctgcgccgg tccgaacccg ggttgcgcgg
    38821 ggagcgcttc tcctggtcgg acagcaccga ggacgtgctg gccttcaccc gcgacgacgt
    38881 cgtgtgcgtc gtcaacctcg gcaccgcgcc ggtgccgctg cccgaccacc acgaggtgct
    38941 gctgaccagc gtcgacctcg acggtgacca cctgcccgct gacgccgccg cctggctgcg
    39001 cgcctgatcg acacgaagga aagacgatga agtcctccgc cgcaaggcca ctgctgacca
    39061 gactcgcgac cgcggcgatc gtgctgccct tggtcctgac cgcgtgcggc tccgatcccg
    39121 acgaccaggt gggcgccgac ggcaaggtcg tcatcaccgt cgcgatggac tcgggcctgg
    39181 agaaggccgc gatcgacgcg ttcaccaagc gcgccgagca gttcgaggcc gcgaacgccg
    39241 atgtcgacgt ccgcacccag gagtacacct ggaccgccgc gtcgttcacc gcccagctcg
    39301 ccggcggcac catccccgac gtgttcaccg tgccgttcac cgatggccgc ggcctgatcg
    39361 agcgcaagca gatcgccgat gtcagcgagc aggtcgccaa gctgccctac tcctcctcgc
    39421 tgaacccgaa catcgccaag gccgggcagg cggcggacgg caggcagtgg gcggtgccga
    39481 tcgccgccta cggacaggcg ctgcactaca accgcacgtt gttcacccag gccgggctgg
    39541 acccggacaa gccgcccacg acgtgggccg aggtgcgttc cgcggccaag cagatcaccg
    39601 agcgcaccgg ccagaccggc tacgcccaga tgacctcggg caacaccggc ggctggatcc
    39661 tgaccacgct cgactacgcc ttcggcggcc gcatcgagaa gatcaccggc gaccaggccg
    39721 aggccaccgt ggacaccccg gagatgaccg aggtgctcga caccgtgcga gccatgcgct
    39781 gggaggacaa cagcatgggc gcgaacttcc tctacgactg ggccggcatc aaccaggact
    39841 tcgccgcggg ccgcatcggc atgtacgtct ccggcggcgg caactacggc aacctcgtca
    39901 cccagaacgg cctcaaggcc gccgactacg gggtcgccgc cctgccgctg gcggacgagc
    39961 cggacgcggg cgtgctcggc ggcggcacgc tggccgtggt gagcccgaag atcggcgagc
    40021 gcagcaagga agccgccgtc aagtggatcg acttctacta catgggcaag ctgaccgacc
    40081 aggaggcggc cgtcgccgac gccaagacgc tggccgagac caaccagccc gtcggcgtgc
    40141 cggctctgcc cgtggtggac cgtgcgacct acgacaagca acaggagtgg accaagcagt
    40201 acgtcaacgt gccgttggac cagatgacgc cgtacacggc gaagatgttc gaccagccgc
    40261 tggtcaccga gccgacccgg tccacccagg acgtctacaa gatcctggac cggacggtgc
    40321 aggcactgct caccgaccag gccgcagacg tgcccgccct gctggccgag gccgacgccg
    40381 aggtgcaggc ccagatcggc cggggctgac gtggccgtcc gatcccactc ccgcgtggcg
    40441 gcggtccccc cgccgccacg cgggccccgc ccgccgcgac ggcggcgcac gcccgccacg
    40501 tgggtgcgcc gcggtgggtt gagcaccctg gtcttcctgc tgccgctgct gctggtgttc
    40561 ggggtcttct cctgggcgcc gatcgtgcag tcggtggtga tgagcttcca gcgcaccaac
    40621 ctcgtggggc ccgtcgagtt cgtcggcttg gacaacttcg cccaggtgct gtcggacccg
    40681 ctgctgtgga ccgcgttgcg caacacggtg tggttcgcgg tgctggcgct gctgttcggc
    40741 tacccgctgc cgctgctggc cgcggtgctg atcagcgagg tccgccaccg caaggggctg
    40801 ttcagcgcgt tggcctacct gccggtggtg atcccgccgg tggtcgcggt gctgctgtgg
    40861 aagttcttct acgacgccgg cccgaccggg gtgttcaaca cggtgctggg ctgggtcggg
    40921 ctcgggccgt ggcagtggct gcagaacccg ggcagcgcga tgcccgcgct ggtgctggag
    40981 gccacgtggg ccgccgccgg cggcacggtg atcatctacc tggccgcgct ggccggggtg
    41041 cccgccgacc tgtacgaggc cgccgagatc gacggctcgg ggatctggcg caaggtctgg
    41101 cacgtcacgc tgccgcggct gcggggcgtg ctgctggtga cgttcatcct ccagatcatc
    41161 ggcaccgcgc aggtgttcct ggaaccgttc ctgttcaccg gcggcggtcc cgcgaactcg
    41221 accaccaccc tgctgctgct gatctacgac tacgcgttcg cgaacagcct cggcggcgac
    41281 tacggcgcgg ccaccgcgct gagcatcatg ctcgcggccg tcctggcgct gttctccacc
    41341 gcgtacttcc ggttgacgag atcctggagc gcgtcgtgaa ccgaggtctg gtctcgccca
    41401 ccgagtgggc gaccacccgc acccggctgg tgctgcgcac ccttcaaggg ttgttgctcg
    41461 gcactctgct gctcgtcgga ctgggacccg tgctgtggct ggccaaggcc gccgtcacgc
    41521 ccacccagga cacactgcgg gcacccctgt cggtgttccc ccacggcttc gacctgtcca
    41581 acctggtcac cgcgtggacc cgagtggaga tcgacaagta cttcctcaac accgtctggc
    41641 tcgccgccgg ctcgtgggcc gtgcagctgg tggtggccac caccgccggg tacgcgctgg
    41701 ccgtgctgcg gccccgctac ggagccctga tcaccggcgt ggtgctgggc acgctgttcg
    41761 tcccctcgat cgtgctgctg gtgcccctgt acttgaccgt ggtcgacacc ggcatgatca
    41821 acacgttctg ggcggtgtgg cttccggccg gcgcgagcgc gttcaacgtc gtcctcgtgc
    41881 agcggttctt cgcgagcctg ccgcgcgagg tgttcgaggc ggcccgggtc gacggcgccg
    41941 ggccgttccg gatcttctgg tcggtggtgc tgccgctgtc gcggcccgtc atcggcgtgg
    42001 tgtcggtgtt cgccgtggtg gccagctgga aggacttcct ctggcccatg ctggtgctgc
    42061 ccgaccccgc ggtgcagccg ctgtccgtgc gcctgcccgc cctgcagcgc tacgtggagc
    42121 tcgacgtctt cctcgccgcc ctggcgatct cgtcgatcat ccccatcgcg ctgttcttgg
    42181 tgttccaacg actgttcctg agcggcggcg cgctggaggg cgcggtcaag ggatgagcca
    42241 gggcccgacg tcgggcctct accctgcgga aagagacaac aacgatgttg agcaacctct
    42301 ccaggagagg actcgcggca ctcaccacga cggtggtggt cgccggtctg atcaccctgt
    42361 ggagcacggc cgcccccgcg gcgccggccg tgctcgaagc cgagtcggcc gcgctctccg
    42421 gcggcgcccg cgtcgagtcc gagcacaccg gctactccgg cgccggctac gccggcgggt
    42481 tcaccgacgc caaccgcggc aacgccaagg cgaccttcac caccaacgcc acggccgggc
    42541 agaacaccct gaccctgcgc tacgccaacg gcaccggctc gacgcgcacc gtgaccctgt
    42601 cggtcaacgg cagcgtccgc caggtctccc tgcccgccac ccccggctgg gcctcgtggg
    42661 gcaccgtgcg ccagagcgtg ccgctcaacg ccgccggcaa ctccatcgcc gtgtcctacg
    42721 gcgccggtga caacggcaac gtcaacctgg acaacatcac cgtcgagccg gcccccgtct
    42781 ccgccggtga tctcgaggcg gagtcggccc agctgtcggg cggcgcccgc gtcgagtccg
    42841 agcacgccgg ttacaccggc agcggttacg tgggcggctt caccgacgtc aaccggggcg
    42901 cggcgacggc gacgttcacc actgccggcg gcagcgccgg gagcagcgag ctgacgctgc
    42961 gctacgccaa cggcaccggc tcgacgcgct ccctgtccgt gtcggtcaac ggcgccgtcc
    43021 ggcaggtgtc gcttcccgcc acctcttcct gggccgcgtg gggaaccgcg accgccgcgg
    43081 tgaccctcaa cgccggtgcg aacacgatcg cgatctccta cggcgccggt gacagcggca
    43141 acgtcaacct ggacaacatc aggctgtcca ccgccgtgcc gaccaccacg accacgacga
    43201 cgaccaaccc gccgggaccc gccggcacct acgaactgga gacagggttc ctgtccggtg
    43261 gcgcggtggt ggccaccagc ccgtccggcg ccacgggaac cggatcggtg aacctgcccg
    43321 gcaacggcgc gcgcgtcatc cgcagcatca accagaccag ggcgggcaac gccaccgtca
    43381 ccctgcgcca caccaactcc tccacgcgca cggtgaccct gtacgtcaac ggcgtcaagg
    43441 gtgcgcagct gaccctgccc ggcggcaccg gctggcgcac cacgacccac agcgcggcac
    43501 tgcgctcagg gttgaacctc atcggctacc acgtcaccag cggtgacacc ggcggcgtcc
    43561 agctcgacaa catcgcggtc accaacaccg cgggcctggc cgtgcgcggc gcgaccgtgc
    43621 cctacaccac ctacgagacc gagagcggca ccggaacccg catcgccggc cgcgcctaca
    43681 cgaccgaggc cgccgaggcg tcggggcgca gcgccatgaa gctcaccggc accggtcagt
    43741 acgtgcaggt cacgttgacc aagcccgcca acgccatcac cgtgcgcgcc ggcctgcccg
    43801 acgacgcctc gggcaacggc accaccgcac cgctggcggt gtacgtgggc ggaaccaagg
    43861 tccgcgacct cgcgctgacc tccaagtaca gctggatgta cggcgactac cccttcaccg
    43921 ccggccccgg cggcgcgcgt ccgcaccgct acttcgacga cgcccgcgtc ctgctgcccc
    43981 agacctaccc ggccggcacg gtgctgcgcc tggccaagga caccaacgcg accagctaca
    44041 tcaccgtgga cctggtcgag gccgaggtcg tcgacggccc gaccacggcc ccggccggtt
    44101 acctcagcat caccgaccac ggagcacggg ccgacgacgg cgtcgacgac agcgccgccc
    44161 tccgctcggc cgtgtccgcc gcccggggca acgcggcccg cggcgtctgg atcccggccg
    44221 gtcggttcac cctctccagc ctggtccagg tcaacggcgt cgacgtgcgc ggcgccggga
    44281 tctggcacac ggtgctcctg ggcgccaacc gacgcggcgg gttctacgtc aacggcgccg
    44341 acaccacgct ggccgacttc accttcgacg gcgacgtcac cacccgcgac cccgacgggg
    44401 cgcccaactc ggacgccttc atcgagggcg agttcggcac cgggtcgctg atcttcaacg
    44461 tggcggccaa ccacgccaag gtcggtctgt ggatcaagca ggccgacggc ctgctcgcct
    44521 cgggcatgcg catccgcaac acgatggcag acggtctgaa catcaacggc aacaccgcca
    44581 acgtccgcgt cgagcagagc gacttccgca acaccggcga cgacgcgctg accatgtggt
    44641 cctgggagtc cgcgggcacc gtcagtcgca gcgtgttcgc cttcaacacg gtcgcgctgc
    44701 ccatcctggc caacggcgtg gccatctacg gcggcaccga caaccgcgcc gaggacaacc
    44761 tgatcaccga caccgtgttc aacggctccg gcgtcatgct ctccacctgg cacgcgtcca
    44821 tgccgttcaa cggcacgacg accgtgcagc gcaacaccct cacccgcacc ggcacccgca
    44881 actgggactg gcacacccac accggcgcgg tctggctgtt cgccgaacgc tccgacatca
    44941 ccggcgcggt cgtgctgcgc gacctggaga tcaacgacag caactaccac ggcctgctgc
    45001 tgagctggaa caaggccgtg cgcgacctga ccgtcgccaa cgtcaggatc aacggcaccg
    45061 gcggcgccac cgagtccttc gacgacggcg ccgggaccgt caccaacgcc aactcccacg
    45121 gcacctactt ctacctcatg tccggcaccg gccggttcga cggcgtgacc gtctccgggc
    45181 tcaagggcac gggcagccgc gggatggtca acgacgagaa ccggtacacc gtccagcgcg
    45241 gcagcggcaa ctccggctgg tgaaccaccg gtgcgacccc gcgcgtgact tcagcggggt
    45301 cgcaccggtg cccggatcga cgcaggaaca ccacccggca cagaccagga agcaccacga
    45361 atgacccctt ggtggcagga cgccgtgttc taccaggtct acccccgcag cttcgccgac
    45421 tccgacggcg acggcgtggg cgacctgccc ggagtccgat cccgactggc ctacctgcgt
    45481 gcgctcggcg tggacgcggt gtggctgtca ccgttctacc tcagcccgca ggccgacggc
    45541 ggctacgacg tcgaggacta ccgggcggtc gacccgctgt tcgggaccac ggacgacgca
    45601 cgggcgctgc tcgccgacgc ccacgcactc ggcctgcgcg tcatcgtgga cgtggtgccc
    45661 aaccactcct cgtcgcgcca cccgtggttc cgggaggccc tggccgcacc gggctccgac
    45721 caccgtgccc gctaccactt ccgccccgga cgcgacggcg ggccgcccaa cgactggcag
    45781 tcgctgttcg gcggcccggc gtggacccgc accaccaacc ccgacggcac gcccggcgac
    45841 tggtacctgc acctgttctc gcccgaacaa cccgacttcg actggaccca cccggccgtc
    45901 gccgaggagt tccggtccgt gctgcggcac tggctcgacc tgggcgtgga cggctttcgc
    45961 gtcgacgtgg cccacggcct ggtcaaagca cccgggctgc ccgaccacgg catgccgacc
    46021 cacctgctgg acctcaccgc caccccgttc tgggaccagg acggggtcca cgccatctac
    46081 cgcgagtggc ggcggctgct ggacgcctac ccgggcgagc gcgtagcggt ggccgaggcg
    46141 tggggcccga cgctgacgcg caccgcccgc tacgtgcggc ccgacgagct gcaccaggcg
    46201 ttcaacttcc accacctgac ctgcccgtgg gacccggtcg cactgcgcgc ggtcatcgac
    46261 gactcgctga gcgccatgtc cgccgtgggc gcacccgcga cctgggtgct gtccaaccac
    46321 gacgtggtcc gccacgcgac caggctcgca cccgacgccg acgcggggac ggggctgcgc
    46381 cgggcccgcg cggcgacact gctgatgttg gcgctgcccg gctcggccta cctctaccag
    46441 ggcgaggagt tgggcctgcc cgaagtgcgc gacctgccgc cacacgcacg tcgtgacccc
    46501 gcgttcgccc gcacccgcgg ccgtgacggg ttccgcgacg gctgccggat cccgctgccc
    46561 tggtggggaa cgcaaccgcc ttacggcttc agcccgtccg atacccggac gtggctgccc
    46621 caaccctcgc actggggcga ctacacggtg gccgcccaga ccggcgaccc ggcttcgacc
    46681 ctggagatgt accgcgccgc gctgacggct cgcaagaccg tgcgcggcga actggtctgg
    46741 ctgcccaccg cgtcgcacgt gctcgcgttc gaacgcggca ccgcgcgctg cgcggtcaac
    46801 ctgggcgacc ggacctgcac catcgacacc ggcggcgtcg accacatcct cactgccagt
    46861 ggccccgtgc gccatgacgg ccatctcacg agcgtgccac ccgacacgac gatctggtgg
    46921 cggaccggca ccgcgggttc cgggtcgctc tgacgcccgg caggaccgac cacgagcagc
    46981 cgggctcgtg cggaccgcgg ctgtgcccga caacccgggg cggcgcatga ccgcgaagcc
    47041 gtgcgccatg aagccgagcc gatgccgtgg gaaccctcct cacacaaagg ggcgtcgtgg
    47101 tctattggac ctggagaatg gggctgtgca gctccacgtg gtagctcgct tcccagactt
    47161 ggccgacgga gacgtactcc gcacttctgc gcgggatggc gcaggtggcg gtgggagtgg
    47221 atttgacgga gtgcgcaggg acgaggaagt tgctccagac gccgccggcg caggtgatcg
    47281 acgttccgct gcgggt
//
