LOCUS       NZ_CP064192            10798 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Saccharothrix sp. 6-C chromosome, complete genome.
ACCESSION   NZ_CP064192
VERSION     NZ_CP064192.1
KEYWORDS    RefSeq.
SOURCE      Saccharothrix sp. 6-C
  ORGANISM  Saccharothrix sp. 6-C
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharothrix.
REFERENCE   1  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Saccharothrix texasensis strain 6-C
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) College of Life Sciences, Chongqing
            University, University Town Road, Chongqing, Chongqing 401331, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 10:20:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,916
            Genes (coding)                    :: 7,819
            CDSs (with protein)               :: 7,819
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 78 of 97
            Pseudo Genes (internal stop)      :: 6 of 97
            Pseudo Genes (multiple problems)  :: 27 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:34:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1307287
            Orig. end                         :: 1318085
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064192.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10798
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10798
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10798
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5798](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5798)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(599..612)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.86"
                     /tool="antismash"
     gene            complement(728..3952)
                     /locus_tag="IOD16_RS06160"
                     /old_locus_tag="IOD16_06155"
     CDS             complement(728..3952)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099298.1"
                     /locus_tag="IOD16_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06155"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_236594777.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.6e-60, bitscore:
                     203.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSKRMRGLVWGAVLVAAGLTASGPGVSGAEEARPTTGEHHEVTL
                     ITGDKVVLLDDRVSALVAAPGRERAVFHSYRRDGHLHVVPRDAAKAVSQGKLDPRLFDV
                     TGLVEAGYDDRGRDTVPLIVTGEQEPAAAGLRVGRPLPAVGSYAAQVVKSEAGDTWRTL
                     VSRASVRKVWLDGVRRPSLDRSTAQIGAPTAWRAGHTGKGVKVAVLDTGVDQDHPDLAG
                     HEVAERNFTDDPDNTDGVGHGTHVAATIASSGAKYKGVAPDADLLDGKVCVLSGCQESA
                     IVAGMQWAAEQGADIVNLSIGGGDTAELDPLEEAVNTLSARTGVLFVIAAGNNSRPETI
                     SSPGSADAALTVGAVDRQDGIAAFSSRGPRVGDGAVKPDITAPGVDIVAAKSSSGTVGT
                     PAGDGYVSMSGTSMATPHVAGAAAVLAQQHPDWTGAQIKAALVASAKNNPALTAFDQGA
                     GRVDLAKAITTSVTAEPSSLALGLQEWPHTDDTPITKTVTYRNEGAAPLTLSLATQVTG
                     PDGGTAPAGLVGVSPAKVTVPAGGAATASVTADTRLGSQDGLYVGSVVATGGPTPLRTA
                     LSVNREVESYDVRFDFVDGSGAAAADYYTSVIGLSNGTFAFPYDADGSFTLRLPRGEYF
                     TNSDVQTDDTRLALLPRPGLSVTADTTVTLDARTAKPVKITPPDAGAEEALGDVTMVRA
                     HGDRQASVSTAFLGGFGPNVSIAHVGPELAAGDLTALLGAQFRGTPDGDAPVTYRLAWT
                     RQGSMPVGFVKDVAASELAEVRTTFGPGPAGRTFGHGGNPITAGGVGGWSWLPSVASPG
                     EAVDRVTADLAWSWGFLQFGADGAVEATLTSPERTYQRGAAHDERFNDPVFSPALPESR
                     SPYLARSGDEISFAVPLFTDRAGNGGNAAVSSARTTLLRDGTKVGETPYAANGLFEVPS
                     GAAVYRVETDAVRTAGTSEFATKVSAAWTFRSDTAADDRQVPLPLSVVRFTPELDAGGA
                     TPKGRSLRVPLTVQQQEGAANGRVDRIDVEVSFDDGTTWTAAPVSGGVATIANPGAAGY
                     GSIRVKATDSDGNALEHTVIRAYKIV"
     misc_feature    complement(3931..3944)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    complement(4111..4124)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.17"
                     /tool="antismash"
     misc_feature    4133..4144
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.38"
                     /tool="antismash"
     gene            complement(4145..4606)
                     /locus_tag="IOD16_RS06165"
                     /old_locus_tag="IOD16_06160"
     CDS             complement(4145..4606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006238756.1"
                     /locus_tag="IOD16_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06160"
                     /product="hypothetical protein"
                     /protein_id="WP_236595123.1"
                     /transl_table=11
                     /translation="MLLLATACGAIDAGGTACTAIGTRTGVSVDVEHPGVVSGTIEVCW
                     DDFCATPGLELYPSSRVVGTTCTGASPDDSCSARSEPTEGKHGFADLPQLPVKPVTVTL
                     KLLDQSGSALVDRNIALTPEMVYPNGPDCPAGGPQAGISVGADGSVTER"
     gene            complement(4660..5004)
                     /locus_tag="IOD16_RS06170"
                     /old_locus_tag="IOD16_06165"
     CDS             complement(4660..5004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099301.1"
                     /locus_tag="IOD16_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06165"
                     /product="hypothetical protein"
                     /protein_id="WP_123743266.1"
                     /transl_table=11
                     /translation="MTQPQRDRLAAAQAELLRALLADGAVPEGFDAERVRIEKRALLGK
                     RRGIVAMLQPEVAAELGDRFRPLFDAYAGSHPKEVGTRFREDAARFAEWAVARGELAPP
                     KRRRWWRRAT"
     gene            complement(5001..5798)
                     /locus_tag="IOD16_RS06175"
                     /old_locus_tag="IOD16_06170"
     CDS             complement(5001..5798)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013224517.1"
                     /locus_tag="IOD16_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06170"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_201439240.1"
                     /sec_met_domain="DUF692 (E-value: 4.2e-86, bitscore: 287.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLGVGIGWRPEIDLTVERLPGVDFVEVVAENLHVGHLPESVLL
                     LRERGVPVLPHAVSLSLGGAEPVDPQRVAHLGALAEALDAPLVSDHVCFVRAGGLDSGH
                     LMPLPRTRDALDVLVANVRAAQQDLPVPLALENVAALLDWPDGELTEGQFLAELVDRTD
                     CHLLVDVANLYANARNLGTDVARFLDEIPLERLAYVHVAGGEEHQGVYHDTHAHAVLPE
                     VLDVLAELRARVDPPGVLLERDDDYPADAELADELAAIRAVLG"
     gene            complement(5835..6662)
                     /locus_tag="IOD16_RS06180"
                     /old_locus_tag="IOD16_06175"
     CDS             complement(5835..6662)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="IOD16_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06175"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_201439241.1"
                     /transl_table=11
                     /translation="MTVATQWTPTSAGSAGSTPEPGWEEQGFLVGGPGRAAEVAVVSLV
                     EAGAVRISRAGLVSAVGRPGHGGSPVQARVLRSLPGSLGDVIAATAKSAEAQSLRPHLV
                     DRGLVTPPVRRQVARRTRQLLIAAAVGAVVATIVLELPFPVALGAVFGGVVLTLVLGRV
                     GRPLTPAGRRAVQRLKAVAVSPNRVALVACYGLLGKVERHHVWEVLGMSPAAAATLRRR
                     SRGSASDGGGGASCGGGCGSCSSSSCGSGSSSGSDSGGSSCGGGGCGGGGGGD"
     gene            complement(6604..7527)
                     /locus_tag="IOD16_RS06185"
                     /old_locus_tag="IOD16_06180"
     CDS             complement(6604..7527)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="IOD16_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06180"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_201439242.1"
                     /transl_table=11
                     /translation="MTFLWWYGPALVVAVVVGLRVKRVAGAVPDRPLSFEEIGYLGGGP
                     VRAVEVALAGLVAENRARVSGPVAAAVPGEEQPATALQAVVLARLARPCDLDELVVGAA
                     TSGPARQLGQRLVAAGLLVSPRRRLARAVLAVVPVAALVVVAVLAGPGGWVTVTALSVA
                     GVLGVLLLLGPPPVLTRRGARAYEEATAGLAPVDPAEVTARYGLVRSARVAEPPVPRKG
                     AARADTAVFDGERAEPIAPAETSQAPLPRRRRAVVVEPQRWQRRNGWLVAGGWFAGGWL
                     AAQWLEGDDGGDSVDADFGGFGGFDA"
     gene            complement(7591..8511)
                     /locus_tag="IOD16_RS06190"
                     /old_locus_tag="IOD16_06185"
     CDS             complement(7591..8511)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="IOD16_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06185"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_201439243.1"
                     /transl_table=11
                     /translation="MERPWGLSGPEFLELYWIALAASLAFAIFVRVRLRGTRGDTPAGA
                     PGLLDIAYLTGGPRRVVETSVASLIDSGALVPARSGSVRVVGEPVADHPVDRAVLADAK
                     RYRYRTLTLLITSLAERDEPREVGRRLAEQGYLVAPDVVKRWLRAGVTPMALLFVVGVV
                     RWINGQVINAPVWFLTLQLVLTGVLIWGLLQAAQVTRTAKGRAEVANARERGISGVWRR
                     TGSANAAEVVALNGFDGHPNITLRVAARPRPRPRVASGGAYAAGSYTASGSGCGSGGGS
                     SCSSGSGSSCGGGGGGCGGGGGGGG"
     gene            complement(8745..9182)
                     /gene="msrB"
                     /locus_tag="IOD16_RS06195"
                     /old_locus_tag="IOD16_06190"
     CDS             complement(8745..9182)
                     /EC_number="1.8.4.12"
                     /GO_function="GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075655.1"
                     /locus_tag="IOD16_RS06195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06190"
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="WP_123743261.1"
                     /transl_table=11
                     /translation="MEPVVGATPKVVHSELEWREILTPKEYAVLRDAGTEPAWVGEYTD
                     TKTEGLYECRACGAELFRSDTKFDSHCGWPSFFSPLAGDSVILREDRAHGMVRTEVLCA
                     TCHSHLGHVFEGEGYATPTDQRYCINSVSLRLVETTGDRAD"
     gene            complement(9229..9543)
                     /locus_tag="IOD16_RS06200"
                     /old_locus_tag="IOD16_06195"
     CDS             complement(9229..9543)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099308.1"
                     /locus_tag="IOD16_RS06200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06195"
                     /product="hypothetical protein"
                     /protein_id="WP_201439244.1"
                     /transl_table=11
                     /translation="MASARAADAPDERPQGAIDDELIGLDPDDPETRAFAEHLGRMQQQ
                     PPSFTIEGTVAGVANFADSANRAGGLRRLTAVIVVGLILLGVLISVWYYLGTLVWVFFY
                     "
     gene            complement(9583..10527)
                     /locus_tag="IOD16_RS06205"
                     /old_locus_tag="IOD16_06200"
     CDS             complement(9583..10527)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099309.1"
                     /locus_tag="IOD16_RS06205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_06200"
                     /product="asparaginase"
                     /protein_id="WP_201439245.1"
                     /transl_table=11
                     /translation="MTHELVAEVWRGEFIESVHHGSVIALDRAGREALSLGRPHDTTYP
                     RSSNKPVQALAMLRHGLDLESELLALACASHSGEDFHVDGVHRVLRAHGLTEADLQCTP
                     DVPIGEDALRSHLAAGRAKAPQYMNCSGKHAAMLATCVVNGWSTHDYLDPGHPLQRAIR
                     DTLEELAGERVGAEGVDGCGAPLLGISLTGLARAFGALAGAPDGPEQRIARAMNAHPEW
                     VGGTNRDVTKLMRAIPGAVAKDGAEGVYAIGLPTGEAVACKIADGSSRARAVVLVAALR
                     KLGVDAPDELATFPVLGHGRPVGAVRPSPALAS"
     misc_feature    complement(10613..10631)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.52"
                     /tool="antismash"
     misc_feature    10616..10634
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.81"
                     /tool="antismash"
ORIGIN
        1 acaccgccgc cgtgtcggcc ttggcggtgc gcgcggccac cgaaccgatg gtgggcagcg
       61 cgcgggtgac ctggacgccg ccggtgcgcg gctggtcgcc ggcgatgatc agcggcacgg
      121 tgtcgcggcg cgcgtcgtcg tagcccgcct cgaccagccc ggtgacgtcg aacaggcgca
      181 ggtcgagctt gccgtcggcc agcggccggg cggcgtcgcg cgggacgacg tgcagccggc
      241 cggcccgcag gaaccggtgg aacgtgatgc cgtcgcggtc cgggcccggc gtgaccgaca
      301 ggagcgagtc accggcgacg acgacccggt cgccggtgac cagggtgacg gtgtgccgct
      361 cgccgccggt ggggcccggt tgggccgacg gcggtaacgg ttcgggcgag gcgatggccg
      421 tcgcggcgcc ggcggtcagc ccgaccgcca acaacgcggc cccccaagcg acaccgcgcc
      481 ttcgtggtcc tggattcaac gcagatacct cccgaatctg gttgagcgcg tcgcgagaac
      541 gcgcctgcgg gaggcgaggc gacagcggtg aacccgaaca ggcgccaccc cccggctctt
      601 cgacgctatc cagtcggggg accggattca gcggcccaac gcggtgcgcg ggggccgccg
      661 ggcagcccaa cgggcgttgc tcgccgggaa gggcgcccgc cggtcgcgaa cgcccctccc
      721 gacccgatca gacgatcttg tacgcccgga tcacggtgtg ctccaaggcg ttgccgtcgc
      781 tgtcggtcgc cttcacccgg atcgagccgt aaccggccgc gcccgggttc gcgatggtgg
      841 cgacaccgcc cgacaccggg gccgcggtcc aggtcgtgcc gtcgtcgaag gacacctcga
      901 cgtcgatccg gtcgacccgg ccgttggccg cgccctcctg ctgctgcacg gtcagcggca
      961 cgcgcaggga ccggcccttc ggcgtcgcgc cgcccgcgtc cagctcgggc gtgaaccgca
     1021 ccaccgacag cggcagcggc acctgccggt cgtcggccgc cgtgtccgag cggaacgtcc
     1081 acgcggcgct caccttcgtg gcgaactccg aggtgccggc cgtccgcacc gcgtcggtct
     1141 ccacccggta gaccgccgcg cccgacggca cctcgaacag cccgttggcc gcgtacggcg
     1201 tctcgccgac cttcgtgccg tcgcgcagca gcgtggtccg ggccgacgac accgccgcgt
     1261 tgccgccgtt gcccgcccgg tcggtgaaca gcggcaccgc gaagctgatc tcgtcgccgc
     1321 tgcgcgccag gtacggcgac cgcgactcgg gcagcgcggg ggagaacacc gggtcgttga
     1381 accgctcgtc gtgcgcggca ccccgctggt aggtgcgttc cggcgaggtg agcgtcgcct
     1441 cgaccgcgcc gtccgcgccg aactggagga agccccacga ccacgcgagg tccgcggtga
     1501 cccggtcgac cgcctcgccg ggcgaggcca cggacggcag ccacgaccag ccgccgacgc
     1561 cgcccgcggt gatcgggttg ccgccgtggc cgaacgtgcg gcccgccggc ccgggaccga
     1621 acgtcgtccg cacctcggcc agctcgctcg cggcgacgtc cttgacgaac ccgacgggca
     1681 tgctgccctg ccgcgtccag gcgagccggt aggtcaccgg cgcgtcgccg tcgggcgtgc
     1741 cgcggaactg cgcgcccagc aacgcggtca ggtcgcccgc cgccagctcc ggtccgacgt
     1801 gcgcgatgga cacgttcgga ccgaaaccgc cgaggaacgc ggtgctcacg ctggcctgcc
     1861 ggtcgccgtg ggcgcgcacc atcgtcacgt cgcccaacgc ctcctccgcg cccgcgtccg
     1921 gcggggtgat cttcaccggt ttggcggtgc gcgcgtcgag cgtgaccgtg gtgtcggcgg
     1981 tgacgctcag ccccggccgg ggcagcagcg ccagccgcgt gtcgtcggtc tgcacgtcgg
     2041 agttggtgaa gtactcgccc ctcggcagcc gcagcgtgaa cgagccgtcc gcgtcgtagg
     2101 ggaaggcgaa cgtgccgttg ctcagcccga tgaccgacgt gtagtagtcg gccgccgcgg
     2161 cgcccgagcc gtccacgaag tcgaaccgga cgtcgtagct ctccacctcg cggttcacgc
     2221 tgagcgcggt gcgcagcggt gtcggaccgc cggtcgccac caccgaaccc acgtacaggc
     2281 cgtcctgcga gccgagccgg gtgtcggcgg tgaccgaggc cgtcgccgca ccgcccgccg
     2341 gcacggtcac cttcgccggc gacacgccga ccaggcccgc gggcgcggtg ccgccgtcgg
     2401 ggcccgtcac ctgggtggcc agcgacaacg tgagcggcgc ggcgccttcg ttgcggtagg
     2461 tcacggtctt ggtgatcggg gtgtcgtcgg tgtgcggcca ctcctgcagg cccagggcca
     2521 ggctcgaggg ctcggcggtg accgaggtgg tgatggcctt ggcgaggtcg acgcggcccg
     2581 cgccctggtc gaacgcggtg agcgccgggt tgttcttcgc cgacgccacc agcgccgcct
     2641 tgatctgcgc gcccgtccag tccgggtgct gctgcgcgag caccgccgcc gcgcccgcca
     2701 cgtgcggcgt cgccatggac gtgcccgaca tggacacgta cccgtcgccg gccggtgtgc
     2761 cgaccgtgcc gctgctcgac ttcgcggcca cgatgtccac gcccggcgcg gtgatgtcgg
     2821 gcttgaccgc gccgtcgccg acgcgcggcc cgcggctgga gaacgccgcg atgccgtcct
     2881 gccggtccac cgcgcccacc gtcagcgcgg cgtcggcgct gccgggcgag ctgatcgtct
     2941 cggggcggga gttgttgccc gccgcgatca cgaacagcac gccggtccgc gcggacagcg
     3001 tgttcacggc ctcttccaac gggtccagct cggccgtgtc gccgccgccg atgctgaggt
     3061 tcacgatgtc cgcgccctgc tcggcggccc actgcatgcc cgccacgatc gccgactcct
     3121 ggcagccgga gagcacgcac accttgccgt ccagcaggtc cgcgtccggt gcgacgccct
     3181 tgtacttcgc gcccgagctc gcgatcgtcg cggcgacgtg cgtgccgtgg ccgacgccgt
     3241 cggtgttgtc cgggtcgtcg gtgaagttgc gctccgcgac ctcgtgaccc gcgaggtccg
     3301 ggtggtcctg gtcgacgccg gtgtccagca cggccacctt cacgcccttg ccggtgtgcc
     3361 ccgcccgcca cgcggtcggc gcgccgatct gcgcggtgga gcggtccagg ctcggtcggc
     3421 gcaccccgtc caaccacacc ttgcgcacgc tcgccctcga cacgagcgtg cgccaggtgt
     3481 ccccggcctc cgacttgacc acctgcgcgg cgtacgagcc gaccgcgggc agcgggcggc
     3541 cgacgcgcag accggcggcg gccggctcct gctcgccggt gacgatcagc ggcaccgtgt
     3601 cacggccgcg gtcgtcgtag ccggcctcga ccagccccgt gacgtcgaac agccgcgggt
     3661 ccagcttgcc ctgcgagacg gctttcgccg cgtcgcgcgg cacgacgtgc aggtgaccgt
     3721 cgcgccggta gctgtggaac accgcgcgtt cccgtcccgg cgcggcgacc agcgcgctga
     3781 cccggtcgtc gaggagcacg accttgtcgc cggtgatcag ggtgacttcg tggtgctcgc
     3841 cggtcgtggg ccgggcctcc tccgcgcccg acacccccgg accgctcgcc gtgaggccgg
     3901 ccgcgacgag cacggctccc cacaccaggc cacgcatgcg tttgctcttc aactgtgtcg
     3961 aacctcccgg tgagtgccgc gcgtggcggg cacgcggccg gaagggctgg ctacccgcgg
     4021 tggcggcgga tgtaccgaga gcgacgtcgc ccttgacgtc atcgacgcta gagggtcacg
     4081 agggggccga cagccgctga ttggtcggca tgttcttgac caattcagcc gagcaaacgg
     4141 ttacctaccg ttcagtgaca gagccgtcgg caccaactga gatacctgcc tgtggcccac
     4201 cggctgggca gtccggaccg ttggggtaga ccatttcggg ggtcagcgcg atattccggt
     4261 ccaccagggc agaaccggat tggtccagca gcttcagggt caccgtgacc ggcttgacgg
     4321 gcagctgcgg cagatcggcg aacccgtgct tcccttccgt cggctcggag cgcgcgctgc
     4381 acgagtcatc cggcgaagca ccggtgcagg tcgtcccgac gacccggctc gacgggtaca
     4441 gctccagtcc gggggttgca cagaagtcgt cccagcaaac ctcgatcgtc ccggacacca
     4501 cgccggggtg ctcgacgtcc accgaaacgc cggtgcgcgt gccgatcgcg gtgcacgccg
     4561 tcccgcccgc gtcgatcgca ccgcacgcgg tggccagcaa cagcacgccc aagggccaag
     4621 tccttcgcca catgccgctg ggacggaacg ggccgccgat caggttgcgc gccgccacca
     4681 ccgccttctc ttcggcggcg ccagctcgcc ccgcgcgacc gcccactcgg cgaagcgggc
     4741 ggcgtcctcg cggaagcgcg tgccgacctc tttggggtgg ctgcccgcgt aggcgtcgaa
     4801 cagggggcgg aaccggtcgc ccagctcggc cgccacctcg ggctggagca tcgccacgat
     4861 cccgcgccgt ttgccgagca gcgcgcgttt ctcgatgcgc acccgctccg cgtcgaaccc
     4921 ctcgggcacg gcgccgtcgg ccagcagcgc ccgcagcagc tcggcctgcg ccgcggccag
     4981 ccggtcgcgc tggggctggg tcaccccagc accgcccgga tcgcggccag ctcgtcggcc
     5041 agctcggcgt ccgcggggta gtcgtcgtcg cgttcgagca gcacgcccgg cgggtcgacg
     5101 cgggcgcgca gctcggcgag gacgtccagc acctcgggga gcacggcgtg ggcgtgcgtg
     5161 tcgtggtaga cgccctggtg ctcctcgccg cccgcgacgt gcacgtaagc gaggcgctcc
     5221 agcgggatct cgtcgaggaa gcgggcgacg tcggtgccca ggttgcgggc gttggcgtag
     5281 aggttggcga cgtcgaccag gaggtggcag tcggtgcggt cgaccagctc ggccaggaac
     5341 tggccctcgg tcagctcgcc gtccggccag tcgaggagcg cggcgacgtt ctccagggcg
     5401 agggggacgg gcaggtcctg ctgggcggcc ctgacgttgg cgacgagcac gtcgagcgcg
     5461 tcgcgggtgc ggggcagcgg catgaggtga ccggagtcga ggccgcccgc gcgcacgaag
     5521 cacacgtggt cgctgaccag cggcgcgtcc agcgcctcgg ccagggcgcc caggtgcgcg
     5581 acccgttgcg ggtccacggg ttccgcgcca ccgagcgaga gcgagaccgc gtgcggcagc
     5641 acggggacgc cccgttcccg cagcaggagg acggactcgg gcaggtgccc gacgtgcagg
     5701 ttctccgcga cgacctccac gaagtcgacg ccgggcaggc gttcgacggt gaggtcgatc
     5761 tccggccgcc agccgatgcc gacacccagc ttctccacgg gccacctgcc tttcgtcgtc
     5821 gtccccggcc ggcgtcagtc gccgccgcca ccgccaccgc agccgccacc gccgcacgac
     5881 gagccgccgc tgtcggaacc gctgctgcta ccgctaccac agctgctgct ggagcagctg
     5941 ccgcaccctc cgccgcacga cgccccaccg ccgccgtcgg aagcgctccc gcgcgaccgt
     6001 cgccggagcg tggccgccgc ggccggcgac atgccgagca cctcccacac gtggtggcgc
     6061 tcgaccttgc ccaacagccc gtagcacgcg accagcgcga cccggttcgg cgacacggcg
     6121 accgccttga gccgctgcac cgcgcgccgg ccggcggggg tcaacggccg gccgacccgg
     6181 cccagcacga gcgtcagcac caccccgccg aacaccgcgc cgagggccac cgggaacggc
     6241 agctccagca cgatcgtcgc gaccacggcc cccaccgccg ccgcgatcag cagctggcgc
     6301 gtccgccgtg ccacctgccg ccgcacgggc ggtgtgacca gaccccggtc gaccaggtgc
     6361 ggccgcagcg actgcgcctc ggcgctcttg gccgtcgcgg cgatcacgtc gcccagcgag
     6421 ccgggcagcg agcgcagcac gcgcgcctgc accgggctcc cgccgtgacc gggccggccc
     6481 accgcgctga ccaggcccgc gcgcgagatc cgcacggcgc ccgcctcgac cagggacacc
     6541 accgccacct cggccgcccg gcccggtccg ccgaccagga agccctgctc ctcccacccc
     6601 ggctcaggcg tcgaacccgc cgaacccgcc gaagtcggcg tccactgagt cgccaccgtc
     6661 atcgccctcc aaccactgcg cggccaacca cccacccgcg aaccacccgc ctgccaccag
     6721 ccacccgttg cgccgctgcc agcgttgcgg ttcgaccacc acggcgcgcc tgcgccgggg
     6781 gagtggtgcc tgagacgttt ccgcaggtgc gatcggttcc gcccgttcac cgtcgaacac
     6841 cgccgtgtcc gcccgcgccg cccccttgcg cggcacgggc ggctcggcga cgcgcgcgga
     6901 ccggaccagg ccgtagcggg cggtcacttc ggccgggtcg accggggcga ggcccgccgt
     6961 ggcctcctcg tacgcccgcg cgcccctccg cgtgaggacg ggcggcggac ccagcagcag
     7021 caggaccccg agcacgccgg cgaccgacag cgcggtgacc gtcacccacc cgcccggacc
     7081 cgcgaggacg gcgaccacca cgagcgccgc caccggcacg accgccagca ccgcccgcgc
     7141 caaccgccgc cgcggcgaga ccagcaggcc tgccgcgacc aggcgttgcc cgagctgccg
     7201 ggcgggaccg ctggtggccg cgccgaccac gagctcgtcc aggtcgcacg gccgggcgag
     7261 ccgggcgagc acgaccgcct gcaacgcggt ggccggctgc tcctcgccgg gcaccgccgc
     7321 ggccaccgga ccggacaccc gcgcccggtt ctcggccacc aacccggcca acgccacctc
     7381 gaccgcccgc accgggccgc caccgaggta accgatctcc tcgaacgaca gcggccggtc
     7441 gggcacggcg ccggcgaccc gcttcacccg caggcccacc accaccgcga cgacgagcgc
     7501 cgggccgtac caccacagga acgtcatggc cgccacccta ggagccgtcg ggccgcaccc
     7561 ggccgtcgtc acggaagcgt aagcaccccg tcagcccccg cccccgccgc cgccaccgca
     7621 gccgcccccg ccgccgccgc agctgctgcc actgccgctg gaacagctgc tcccgccgcc
     7681 gcttccgcac ccgctgcccg acgcggtgta cgagccggcc gcgtaagcgc cgccggacgc
     7741 cacccggggg cggggacgcg gacgtgccgc cacgcgcaac gtgatgttcg ggtggccgtc
     7801 gaaaccgttg agggcgacca cctcggcggc gttcgccgag ccggtccggc gccacacccc
     7861 ggagatcccg cgctcgcggg cgttcgccac ctcggcccgg cccttcgcgg tgcgcgtcac
     7921 ctgggccgcc tgcagcagcc cccagatgag cacgcccgtc agcacgagct gcaacgtcag
     7981 gaaccacacg ggcgcgttga tcacctgtcc gttgatccag cgcacgacac cgacgacgaa
     8041 caacagcgcc atcggcgtga cacccgcccg caaccaccgc ttcaccacgt ccggcgcgac
     8101 caggtagccc tgttcggcca gccgccggcc gacctcgcgg ggctcgtccc tctccgccag
     8161 cgacgtgatc agcagcgtca acgtccggta gcggtagcgc ttcgcgtcgg cgagcacggc
     8221 ccggtcgacc gggtggtcgg cgacgggctc gccgacgacg cgcacggacc cgctgcgcgc
     8281 gggcaccagg gcgcccgagt cgatgagcga ggcgaccgac gtctccacga cccgccgcgg
     8341 tccgccggtc aggtaggcga tgtccaacaa gccgggcgcg cccgcggggg tgtctccccg
     8401 cgtcccccgc aggcgcactc ggacgaagat cgcgaaggcc agcgacgcgg ctagcgcgat
     8461 ccagtacagc tcaaggaatt ccgggcctga aagcccccac ggtcgctcca cggtccaccc
     8521 cctgtggccc tcggtgggtc cacgcccacc agctaggggg aatcgtgtgc gccaggccac
     8581 acttcggcaa gggggcttga gcaagcctta gggtcggccg tccgacggtg gtcggtcagg
     8641 aggacgacgc gccgtccacg ccgccggagc cttcgccgtc agtgcccttg aagatgcgca
     8701 tgattcctcc tggagtggat cagtcatcat tcggcgtagc gctttcagtc tgctcgatca
     8761 ccggtggttt cgaccagacg caaactcacc gagttgatgc agtagcgctg atccgttggc
     8821 gtggcgtagc cctcaccctc gaacacgtgc ccgaggtggc tgtggcaggt cgcgcacaac
     8881 acctccgtgc ggaccatgcc gtgcgcgcgg tcctcgcgca ggatcaccga gtcaccggcc
     8941 agcggcgaga agaacgacgg ccagccgcag tgcgagtcga acttggtgtc gctgcggaac
     9001 agctcggcgc cgcacgcgcg gcactcgtag aggccctcgg tcttggtgtc cgtgtactcg
     9061 ccgacccagg cgggctcggt gcccgcgtcg cgcagcaccg cgtactcctt gggggtcagg
     9121 atctcccgcc actccagctc ggagtggacc accttcgggg tggcgccgac gacaggttcc
     9181 atacctccac gttagacgag tccccgacgg ccgagccgcc ggcgcgggtc agtagaagaa
     9241 cacccagacg agggtcccca ggtagtacca gacgctgatc agcaccccca gcaggatgag
     9301 gcccaccacg atgaccgcgg tgagcctgcg caggccgccc gcccggttcg ccgagtccgc
     9361 gaagttcgcg acgcccgcga ccgtgccctc gatggtgaag ctgggtggct gctgctgcat
     9421 ccgaccgagg tgctcggcga acgccctggt ctcggggtcg tcggggtcga ggccgatcag
     9481 ctcgtcgtcg atcgcgccct gcgggcgctc gtcgggtgcg tcggcggctc tggcgctggc
     9541 catggcaccc agcgtagccg gcgcttcaag ccgctgggcg gctcagctcg ccagggcggg
     9601 cgacggtcgg acggcgccga ccgggcggcc gtgaccgagc accgggaacg tcgccagctc
     9661 gtccggcgcg tccactccca gcttgcgcaa cgcggccacc aggaccaccg ccctggcgcg
     9721 gctggacccg tccgcgatct tgcacgccac ggcctcgccg gtcggcaggc cgatcgcgta
     9781 gacgccctcc gcgccgtcct tggccaccgc gcccgggatc gcccgcatga gcttcgtgac
     9841 gtcgcggttc gtgccgccga cccactcggg gtgggcgttc atcgcccgcg cgatccgctg
     9901 ctccggaccg tcaggcgcac cggccagcgc gccgaacgcc ctggccaggc cggtgaggct
     9961 gatgccgagc agcggcgcgc cgcagccgtc gacgccttcc gcgccgaccc gctcgccggc
    10021 cagttcctcc agggtgtcgc ggatggcccg ctggaggggg tggccggggt cgaggtagtc
    10081 gtgggtcgac cacccgttga ccacgcaggt ggccagcatg gcggcgtgct tgcccgagca
    10141 gttcatgtac tgcggcgcct tggctcggcc cgccgccagg tgcgacctga gggcgtcctc
    10201 gccgatcggg acgtccggcg tgcactggag gtcggcctcg gtcaggccgt gcgcgcgcag
    10261 gacgcggtgg acgccgtcga cgtggaagtc ctcgccggag tggctcgcgc aggccagggc
    10321 cagcagctcg ctctccaggt cgagcccgtg gcggagcatg gccagcgcct ggaccggctt
    10381 gttggacgag cgcgggtagg tggtgtcgtg cgggcggccg agggacagcg cttcccgacc
    10441 cgcgcggtcg agggcgatga cggaaccgtg gtgcacggac tcgatgaact caccacgcca
    10501 gacctcggcg accagttcgt gcgtcatgcg tcctcccgac ccttcgcggc cgtgcgcgcc
    10561 cgtgtgcggc cgtgcccctg tgcgcggcga tgcgtgtggt gcgccgacac gctgccaact
    10621 gtcgacagtt aacatcgcgg gtgacatctc gcgctaggag acgttcgtga cacctcccct
    10681 gcacttgagc ttggccggtc aggccgtgga cgtgctccgc gagctggtgc tgaccggcga
    10741 catcccgccc ggcacgcggg tgaacgaggt cgagctggcc cagcggctgg gcatctcc
//
