LOCUS       NZ_CP064192            22535 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Saccharothrix sp. 6-C chromosome, complete genome.
ACCESSION   NZ_CP064192
VERSION     NZ_CP064192.1
KEYWORDS    RefSeq.
SOURCE      Saccharothrix sp. 6-C
  ORGANISM  Saccharothrix sp. 6-C
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharothrix.
REFERENCE   1  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Saccharothrix texasensis strain 6-C
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9045220)
  AUTHORS   Feng,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) College of Life Sciences, Chongqing
            University, University Town Road, Chongqing, Chongqing 401331, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 10:20:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,982
            CDSs (total)                      :: 7,916
            Genes (coding)                    :: 7,819
            CDSs (with protein)               :: 7,819
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 78 of 97
            Pseudo Genes (internal stop)      :: 6 of 97
            Pseudo Genes (multiple problems)  :: 27 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:34:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 965423
            Orig. end                         :: 987958
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064192.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22535
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22535
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22535
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12535](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12535)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            244..918
                     /locus_tag="IOD16_RS04555"
                     /old_locus_tag="IOD16_04550"
     CDS             244..918
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098997.1"
                     /locus_tag="IOD16_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04550"
                     /product="hypothetical protein"
                     /protein_id="WP_201438991.1"
                     /transl_table=11
                     /translation="MKEKRRELAGLCRVAVDRPRWQLGFAAVVSAWSLAWVVGQAFGEP
                     SPLEVLPVRWAGLPTGWLDATRGWFDGRTGFLAVVGGLLWAMTSASRQASAVVGWLAVM
                     ASAEDVGYVAVRWALLSLVVFLAVMGLVSITGRRAFVVDRVAVIPRDVARAGATAAALS
                     AVVPLVAPGLVLARLVGPYVTRPPRRRPGTPIVRAASAERPPAGGTPGELPEPVPAQRG
                     SR"
     gene            1028..1708
                     /locus_tag="IOD16_RS04560"
                     /old_locus_tag="IOD16_04555"
     CDS             1028..1708
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098998.1"
                     /locus_tag="IOD16_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04555"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_236594755.1"
                     /transl_table=11
                     /translation="MGLPVRIHQDVRVPENPAENRLAKVMRRQPVQQRGAATVSAIVDA
                     CATLLNDYDYDDITTARIVELAGVPIGSFYQYFPDKRSVVHALALRGMEEYLGRVETLF
                     TEGRIAEDWREAVRQVVAVYLRMLVEIPGFGRVRFSDLLDGHRLDSSVDQYELMAERLR
                     DLFVSRFAVRGDAPVMLTFRMAAQTADAMFKLAERVDPDERPVVLRTADGVILKMLSTV
                     FDPS"
     misc_feature    1034..1036
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    1091..1093
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1763..3214
                     /locus_tag="IOD16_RS04565"
                     /old_locus_tag="IOD16_04560"
     CDS             1763..3214
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336130.1"
                     /locus_tag="IOD16_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04560"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_201441200.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.9e-44, bitscore:
                     151.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVIGGGPVGENAAARTAAGGLRTALVEAERVGGECSYWACMPSK
                     ALLRPGHALAAARRVPGVPVGERLDPAEVLKRRNSFTSDWDDSGQVEWAEGAGLTVVRG
                     RGRLAGERRVDVDGRVLTATKAVVVCTGSVPRIPSLPGLADVPYWTSREATSAQEVPRS
                     LVVLGGGVVGVEMAQAWARLGSDVTLVVSGERPLPKFEAFAGELVADGLKEDGVRLVTG
                     VKAVGVSTSDGSGGAGSGGEGLGGSGLGGSGLGGSGLGGAGEVSLTLSDDTVVTGAHLL
                     IATGRQPATFDLGVEQFGFTAGEALEVDDTGRVSGVDWLYAAGDVTGRALLTHQGKYAA
                     RAVGTAIVTGATDPEPWTAPVATADHTAVPQVVFTDPEVASVGWTEAQAREAGLDIRVV
                     DLDIAVAGSSLHADGYRGKARMIVDERKRTLVGVTFAGPDVAELVHAATIAIVGEVTVD
                     RLWHAVPAYPTISEVWLRLLEAYGL"
     misc_feature    complement(3222..3238)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    complement(3235..3253)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.32"
                     /tool="antismash"
     misc_feature    3238..3256
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            3333..3704
                     /locus_tag="IOD16_RS04570"
                     /old_locus_tag="IOD16_04565"
     CDS             3333..3704
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099000.1"
                     /locus_tag="IOD16_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04565"
                     /product="hypothetical protein"
                     /protein_id="WP_201438993.1"
                     /transl_table=11
                     /translation="MTRGTVAVAMGAVLWCAFVIASTFLPGGPSWPPVAVHLPGFLIVP
                     VVLHTLFRARSSALLCLAHVPKSVLFTGFAIAVGGWLFSFGAIAGKPGTETLCAVAGLV
                     IVLHVAFGLIGVGMVRTGR"
     gene            complement(3753..5000)
                     /locus_tag="IOD16_RS04575"
                     /old_locus_tag="IOD16_04570"
     CDS             complement(3753..5000)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099001.1"
                     /locus_tag="IOD16_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04570"
                     /product="hypothetical protein"
                     /protein_id="WP_201438994.1"
                     /transl_table=11
                     /translation="MRLIRLGTEPSAVGADVRAALSTWGNGDAVLGGVALLGVRPPDSP
                     RELDAVIVLPRGVLVVVGVDLPDPAMRLEAPLNGQWKIDGWPLTRPDGAMSPAAEALAA
                     TTAVARRIQDMRGEPLPVTTVVAVGPYVGQVVQPTVDLNRGVRVLHPKPTTLLAAAREL
                     ATSDRPCSAEHAAKLVAVLATTGAPPTRQHLIAEGFSDAAADLASASTMLLPKVTPAPA
                     ARKLLPYAAGAVVALLLVIALIISLSSNDTADSATSTTTAPQPTTVVVDGRNFSPRGAD
                     RTDDCASHAFGDVRGWLTGHLCMQLRRAQYETTVDGRKVGVAIAELSLPDSTRASELHA
                     IASAAGSGGVTTLVKDGKGWPGGPKTFDRSAIRVSAKGAQLRITQVVWAEGEQDPADPE
                     LTEIADQALRLPAAQG"
     misc_feature    complement(5140..5155)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    5406..5422
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.36"
                     /tool="antismash"
     gene            5512..6015
                     /locus_tag="IOD16_RS04580"
                     /old_locus_tag="IOD16_04575"
     CDS             5512..6015
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074684.1"
                     /locus_tag="IOD16_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04575"
                     /product="DUF3145 domain-containing protein"
                     /protein_id="WP_123743506.1"
                     /transl_table=11
                     /translation="MSTRGSSSGVVYVHSSPSAVCPHVEWAISGTLGERADLKWAAQPA
                     APGQLRAECNWTGDAGTGARLVSALRAWPMLRFEVTEDPSPGVDGVRYCFAPVLGLWHA
                     RTSANGDIVVSEDQLRALAARSRGGESFAHGVDEILGAAWDDALEPFRRAGDGAPVTWL
                     HRVG"
     gene            complement(6359..8056)
                     /locus_tag="IOD16_RS04585"
                     /old_locus_tag="IOD16_04580"
     CDS             complement(6359..8056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099004.1"
                     /locus_tag="IOD16_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04580"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_201438995.1"
                     /transl_table=11
                     /translation="MTYLRALREQRRGIVVLLGWSVLEGVPALLSGRLVGLAVDRGFGA
                     GRPWVGVGWLLLFAAVAVLGGFGLRQVFMRLGAVVEPLRDALVRQVVRGVLHGGSQTRQ
                     PDASAVARITRHVEVVRDATAGVLVQARALLVTTAAALVGLAVTVSSLAWLVILPVVAA
                     LVLFGLLLPSLARGQRRLVLADEESAAVAGTVLLGMRDVVAVGGSEQALHDVMEQVNRQ
                     ASATVRMACATALRGVVIALGGFAPLVLLLLVAPGMVRAGTLSVGEVLGAVVYLSTSVQ
                     PALRRLADTTSTIVLRLVVALRRLAEAAPPVDVPGGDAVPEGREIELSGVTFGWSATAE
                     PVVRSLDLVLPEGAHLAVIGPSGIGKSTLAGLITGMVEPQAGVVRFGGVPVRSVAPGVR
                     HERIALVPQETYLFTGTVRENLALFAPAAPDAALLSAAEAVGATDVITRLGGLAGSVGH
                     AGGGLSAGEAQLLAAARVHASPADVVILDEAASALDPSAEAVVEQAFAARGGTLIVIAH
                     RLSSALRADLVLLMDGGPPLLGSHQDLLADSPLYRDLMAAWQPTPIAP"
     gene            complement(8056..9648)
                     /locus_tag="IOD16_RS04590"
                     /old_locus_tag="IOD16_04585"
     CDS             complement(8056..9648)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099005.1"
                     /locus_tag="IOD16_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04585"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_201438996.1"
                     /transl_table=11
                     /translation="MVLSSVVRRDPRWLLLALNALPATTAGLLLPTALASAVDMALAGR
                     LDRGTVLWLVGLAGVEVLGDAIGVVLAAAITASGATWLRRRLTAHLVALGHPTRFEPGD
                     AVSRLTGDSAIAGGVSVLAVNLGISVVTAAGAITALALLDWRLAVVFLLSVPLAALLVR
                     SHLRLTAADVATYQEVSGELSARLVDAVGGLRTIAASGRADQEAERVLRPLPRLAAAGV
                     GMWSTQARMIWRAGLLLPAVELAVLTAAGFGVVAGRLSVGDVLATLGYVALGMTVVGQA
                     TLLTAIQRARASAQRLDEVLSTPVPAEDAPGGAATGELVLTGVNVPGALHDVELTVAAG
                     TFVAVVGRSGSGKSALASVIGGLTRPSTGRVRRGGSVGYAFERPSLVGTTVGDAVRYGT
                     SRDHDEVEAACRAAQVHDVVVRLPEGYDTPMSAAPMSGGEAQRLGLARAFVRDPAVLVL
                     DDATASLDMVTESTVERAVESALPGRTRVVVTHRAATARRADVVVWLDGGRVRAVGPHS
                     ELWDDDEYRAVFG"
     gene            complement(9795..9959)
                     /locus_tag="IOD16_RS04595"
                     /old_locus_tag="IOD16_04590"
     CDS             complement(9795..9959)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800163.1"
                     /locus_tag="IOD16_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04590"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_123743503.1"
                     /transl_table=11
                     /translation="MDFILDLQDMETPEAASNAMASGGSSSGGGGSTSASGLSLLGCGA
                     HSTVSLVIC"
     CDS_motif       complement(9894..9959)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDFILDLQDMETPEAASNAMAS"
                     /locus_tag="IOD16_RS04595_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9795..9893)
                     /prepeptide="core"
                     /locus_tag="IOD16_RS04595_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="17.80"
                     /molecular_weight="2568.8"
                     /monoisotopic_mass="2567.3"
                     /core_sequence="GGSSSGGGGSTSASGLSLLGCGAHSTVSLVIC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDFILDLQDMETPEAASNAMAS"
                     /leader_location="[9893:9959](-)"
                     /alternative_weights="2586.8"
                     /alternative_weights="2604.8"
                     /alternative_weights="2622.9"
                     /alternative_weights="2640.9"
                     /alternative_weights="2658.9"
                     /alternative_weights="2676.9"
                     /alternative_weights="2694.9"
                     /alternative_weights="2713.0"
                     /alternative_weights="2731.0"
     gene            complement(10001..12535)
                     /gene="lanKC"
                     /locus_tag="IOD16_RS04600"
                     /old_locus_tag="IOD16_04595"
     CDS             complement(10001..12535)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030764.1"
                     /locus_tag="IOD16_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04595"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_201438998.1"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1035.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2e-10, bitscore: 39.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-09, bitscore:
                     36.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYEAYCFADRLFYDVQSSTETSEDDFSQVLPALPEGWAQGDR
                     NIWRHTYPQGVPLPKQGWKIHVSATVLNAGEVLLKSYEYLVARRIPFKYLRTRSIVLAR
                     NSKYAPREGSGKLITIYPADDSELESTLRELSEILKGQSGAYILSDLRYGAGPLFVRYG
                     GFVEQWLEKDGKRVLAIEGPDGALVPDQRKPTFWTPEWVKIPACLEEHLAVRRAGSADE
                     FPYRVLRSLHFSNGGGVYEAIRKSDDQRVVLKEARPHSGLDRLNVDAVARLHREHEMLE
                     KVAGVPGVPEVFERFSAWEHEFMAMSEVPGRPLGQWLGQHYPLTHHEISDEAVAAYTER
                     ALKVIAAVERIIGDVHARGLVFCDLHPLNILVDDDDSISLIDFELAFRVEEDKKPTLGS
                     PGFQAPPDRSGFEIDEHALAALRLYVFLPLITMLELAPVKLQSHVDFIRRRFGLSEEYC
                     AKILAGLERRVDPPTESPTTALDAPEPELPAVLKMVAAAILASATPQRDDRLFPGDVEQ
                     FETGGATFGYGAAGVLHALDVTGQGRFPDHERWLLEAVRRDPPKEPGFFSGAHGIAYVL
                     EEFGHHDLAGELVRSYAAMVPDTEDHGLGSGLAGIALNLLHFAGTRDDETYAEQALELA
                     ERLDTALANVEPPGDKARAGLEHGWSGPALLFLRLFERTGDRRWLDVGVKALERDLAET
                     MIALDGSTQVRDGSARTLPYVGTGSAGIALVLNEFRLVEPDLPVLDKLPELLSATTGEF
                     VIQPALMLGRAGLLATLVHTGGPGHAIDRHLASLAWHAIPYQGGLAFPGIQLRRLSMDL
                     NTGGAGVLLALGTLANGTPMLPFLKAPTLAGR"
     misc_feature    12490..12503
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.98"
                     /tool="antismash"
     gene            13035..13613
                     /locus_tag="IOD16_RS04605"
                     /old_locus_tag="IOD16_04600"
     CDS             13035..13613
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IOD16_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="IOD16_04600"
                     /product="hypothetical protein"
                     /protein_id="WP_201438999.1"
                     /transl_table=11
                     /translation="MSARLLLPAVLLVAAATAGVGVLAREAYQRPVVPPGGQVAAPGSG
                     QSGSVPRSAQPGSGAVQLSVDAAQHPDGQRVREVLQQFFDAINDHDYEQWAKTVTAHRV
                     GQTPRSRWLSDYESSRDGSILVHRIESVSESRLRVLMTFTSTQDVVKAPAELQADCIHW
                     RVVYPLQVDRGTLRVDLGTEGSTSQFTAC"
     gene            complement(13698..15125)
                     /locus_tag="IOD16_RS04610"
                     /old_locus_tag="IOD16_04605"
     CDS             complement(13698..15125)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020730624.1"
                     /locus_tag="IOD16_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04605"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_123743500.1"
                     /transl_table=11
                     /translation="MTVLASRPVNPAADGEPDPRDPEVRLAQLLDPGSVAPLRPRDGSG
                     MFAVRGRINGAKVVAYCSDATRMGGALGSEGCRHIVEAIDVAVRERTPVIGVWHSGGAR
                     LPEGVESLDGMGQMFAAMIRASGRVPQISVVVGPAAGGGAYGPALTDVVIMAPAGKVFV
                     TGPDVVRSVTGEQIDMDGLGGAEAHGRKSGVVHVVADDEPDAYERARRITGLFAQPGVF
                     DLHSVPDGDDLRALLPEQPQRAYDVKPLVRAILDDDSFEELQAKWAPNVVVGLGRLGGR
                     TVGVIANNPIRKGGCLDSLSAEKAARFVRMCDAFGVPLLVLVDVPGYLPGVGQEWDGVV
                     RRGAKLLHAFGEAVVPRVTLVTRKSYGGAYIAMNSRSLGATAVFAWPIAEVAVMGAKAA
                     VGILHRKKLAAVPDEEREALHAQLVEEHERIAGGVERAVAIGVVDEVIEPTRTRRKLAQ
                     ALAAAPAGRGAHGNIPL"
     gene            complement(15163..16398)
                     /locus_tag="IOD16_RS04615"
                     /old_locus_tag="IOD16_04610"
     CDS             complement(15163..16398)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (67-408). E-value:
                     8.8e-50. Score: 161.7. Matches aSDomain:
                     nrpspksdomains_IOD16_RS04615_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FabF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017984122.1"
                     /locus_tag="IOD16_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04610"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_123743499.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.6e-55, bitscore:
                     187.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="FabF (E-value: 4.5e-168, bitscore: 558.1,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNNDVVVTGLGATTPLGGDVASTWDALLAGRSGVTPLVGGFAE
                     RFELPVRIAARLAVEPTEVLPRVEARRLDRCEQVAVVAARQAWADSGLGEDDVDLERLG
                     VVIGTGIGGAMTLLDQDDLIEASGLRKVSPLTVPMLMPNGPAAHVGLDLKARAGVHAPV
                     SACASGAEALAWAWRMIKTGEADVVVAGGAEACITTITMAGFIQARTMSTRNDDPERAS
                     RPFDVNRDGFVLGEGAGILVLEREDFARARGARIYGKLAGIGTTSDGYHITAADPEGLG
                     QSRAITKALRSADVDPADVGHVNCHATSTPVGDVIEPQAVRRAIGDHPVLTAPKGNHGH
                     LLGASGAVEAITTLLSVRDGIVPPTLNLDDQDPRVQLEVVTGEPRKIELTAAVNNSFGF
                     GGHNVSLVFTGA"
     aSDomain        complement(15175..16197)
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS04615_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="8.80E-50"
                     /label="IOD16_RS04615_PKS_KS.1"
                     /locus_tag="IOD16_RS04615"
                     /protein_end="408"
                     /protein_start="67"
                     /score="161.7"
                     /tool="antismash"
                     /translation="VEARRLDRCEQVAVVAARQAWADSGLGEDDVDLERLGVVIGTGIG
                     GAMTLLDQDDLIEASGLRKVSPLTVPMLMPNGPAAHVGLDLKARAGVHAPVSACASGAE
                     ALAWAWRMIKTGEADVVVAGGAEACITTITMAGFIQARTMSTRNDDPERASRPFDVNRD
                     GFVLGEGAGILVLEREDFARARGARIYGKLAGIGTTSDGYHITAADPEGLGQSRAITKA
                     LRSADVDPADVGHVNCHATSTPVGDVIEPQAVRRAIGDHPVLTAPKGNHGHLLGASGAV
                     EAITTLLSVRDGIVPPTLNLDDQDPRVQLEVVTGEPRKIELTAAVNNSFGFGGHNVSLV
                     F"
     CDS_motif       complement(15448..15492)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS04615_0001"
                     /evalue="1.20E-02"
                     /label="PKSI-KS_m5"
                     /locus_tag="IOD16_RS04615"
                     /protein_end="317"
                     /protein_start="302"
                     /score="8.7"
                     /tool="antismash"
                     /translation="VNCHATSTPVGDVIE"
     gene            complement(16395..16634)
                     /locus_tag="IOD16_RS04620"
                     /old_locus_tag="IOD16_04615"
     CDS             complement(16395..16634)
                     /NRPS_PKS="Domain: PP-binding (9-75). E-value: 2.7e-19.
                     Score: 61.2. Matches aSDomain:
                     nrpspksdomains_IOD16_RS04620_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009947996.1"
                     /locus_tag="IOD16_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04615"
                     /product="acyl carrier protein"
                     /protein_id="WP_053720023.1"
                     /sec_met_domain="PP-binding (E-value: 1.6e-17, bitscore:
                     62.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 0.027, bitscore:
                     13.6, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNEDIQKGLAEIVEEVAGVEAADVTADKSFVDDLDIDSLSMVEI
                     AVQAEDKFGVKIPDDELANLKTVGDAVNYIASNA"
     aSDomain        complement(16410..16607)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS04620_PP-binding.1"
                     /evalue="2.70E-19"
                     /label="IOD16_RS04620_PP-binding.1"
                     /locus_tag="IOD16_RS04620"
                     /protein_end="75"
                     /protein_start="9"
                     /score="61.2"
                     /tool="antismash"
                     /translation="LAEIVEEVAGVEAADVTADKSFVDDLDIDSLSMVEIAVQAEDKFG
                     VKIPDDELANLKTVGDAVNYI"
     gene            complement(16696..17673)
                     /locus_tag="IOD16_RS04625"
                     /old_locus_tag="IOD16_04620"
     CDS             complement(16696..17673)
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099010.1"
                     /locus_tag="IOD16_RS04625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04620"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_201439000.1"
                     /sec_met_domain="fabH (E-value: 1.5e-105, bitscore: 351.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTFSTPAGPAGTRILGMGSYQPETIVSNHDLSLRMDTSDEWIRD
                     RVGIANRRVAKPDELLVDMAIEAGLKAVADAGLTPSDIGAVIVATCTMPSQIPNAAAQV
                     AHRIGITGAAAFDMNAACAGFCYALGTASDLVRAGTAKNVLVIGAEKLTDWVDPDDRST
                     AIIFADGAGAAVVGQSDEPGIGPVSWGSAGDLVDMIHIKDRASSIFQEGQSVFRWATTQ
                     IAPIALKAIELAGIEVSDVDVFVPHQANLRIIEAIAKRLRAKGAREDLVIARDIVDSGN
                     TSSASIPLALDHMRAAGEVRSGDVALLVGFGAGLSYAGQVVRLP"
     gene            complement(17670..18620)
                     /locus_tag="IOD16_RS04630"
                     /old_locus_tag="IOD16_04625"
     CDS             complement(17670..18620)
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (11-289). E-value: 5.6e-44.
                     Score: 142.6. Matches aSDomain:
                     nrpspksdomains_IOD16_RS04630_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099011.1"
                     /locus_tag="IOD16_RS04630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04625"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_328809416.1"
                     /sec_met_domain="PKS_AT (E-value: 7.3e-42, bitscore: 142.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSERVIALLAPGQGSQTPGMLTPWLEVEGAAERVAAWSEATGLD
                     LARLGTTADADEIKDTAVTQPLVVALALLAYEELRRRVELPADTVVGGHSVGELAAAAI
                     AGVLSADDAVSLAAVRGAEMAAACALAPTGMAAVLGGEEDEVLARLDELGLVGANRNGA
                     GQIVAAGPVDALAALVEQPPTRAKIRTLKVAGAFHTRFMAPAEDALRARAAGIVVKDAA
                     LPLLSNADGALVSDGDEVLSRLISQVTRPVRWDACQATLAGHGVTAVVELPPAGALTGL
                     AKRELKGTPTLGLKTPDQLDQVVEMITATPSEVAE"
     aSDomain        complement(17754..18587)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS04630_PKS_AT.1"
                     /evalue="5.60E-44"
                     /label="IOD16_RS04630_PKS_AT.1"
                     /locus_tag="IOD16_RS04630"
                     /protein_end="289"
                     /protein_start="11"
                     /score="142.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PGQGSQTPGMLTPWLEVEGAAERVAAWSEATGLDLARLGTTADAD
                     EIKDTAVTQPLVVALALLAYEELRRRVELPADTVVGGHSVGELAAAAIAGVLSADDAVS
                     LAAVRGAEMAAACALAPTGMAAVLGGEEDEVLARLDELGLVGANRNGAGQIVAAGPVDA
                     LAALVEQPPTRAKIRTLKVAGAFHTRFMAPAEDALRARAAGIVVKDAALPLLSNADGAL
                     VSDGDEVLSRLISQVTRPVRWDACQATLAGHGVTAVVELPPAGALTGLAKRELKGT"
     CDS_motif       complement(18249..18350)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS04630_0002"
                     /evalue="5.20E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IOD16_RS04630"
                     /protein_end="124"
                     /protein_start="90"
                     /score="41.0"
                     /tool="antismash"
                     /translation="VGGHSVGELAAAAIAGVLSADDAVSLAAVRGAEM"
     CDS_motif       complement(18555..18587)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IOD16_RS04630_0001"
                     /evalue="3.80E-03"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IOD16_RS04630"
                     /protein_end="22"
                     /protein_start="11"
                     /score="10.4"
                     /tool="antismash"
                     /translation="PGQGSQTPGML"
     misc_feature    18673..18689
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            complement(18793..19968)
                     /locus_tag="IOD16_RS04635"
                     /old_locus_tag="IOD16_04630"
     CDS             complement(18793..19968)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683044.1"
                     /locus_tag="IOD16_RS04635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04630"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_123743496.1"
                     /transl_table=11
                     /translation="MTSSTALSRATLRTLRRASGDLAAASVAEMEERLPWFRRMPADQR
                     AGVLLLIQNGVSGFVSWLHDPQQAIRLTAEAFRSAPKDISRWVSLRQTVELVRIALELF
                     EQLLPKLAENEAERALLTEGVLRYGREIAFSAATSYAAAAEARGAWDARLEALVVDGIV
                     RGDAEESLLSRATALGWDPAAEATVLVGNPPSDDPPAVVFEVRSRAARVGRPVLLSVQG
                     SRLVVVLGGETDRSESLVRLSDAFGPGPVVAGPTVTSLAEAHRSASDALSGLRAVVGWP
                     AAPRPVRSLDLLPERALAGDPEAEWQLVDRVARPLEEASGSLLETVDAFLEVGGVLEAC
                     ARKLFVHPNTVRYRLKRATELTGRNANDPRDALVLRVALSVGRLARARGLW"
     gene            20085..21596
                     /locus_tag="IOD16_RS04640"
                     /old_locus_tag="IOD16_04635"
     CDS             20085..21596
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (84-287). E-value:
                     1.3e-20. Score: 66.0. Matches aSDomain:
                     nrpspksdomains_IOD16_RS04640_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099013.1"
                     /locus_tag="IOD16_RS04640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IOD16_04635"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_236594756.1"
                     /sec_met_domain="PF00561 (E-value: 3e-25, bitscore: 88.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRFMSVGLVVTAVLATAVAPSFGTARSDPLAEFHTQQLTWSPCK
                     QLLECAELVLPLDYRRPGADRISLVISRKKATDTARRRGVLVLNPGGPGGSGLGMPSFL
                     AGSELAKVYDLIGFDPRGVGGSTALNCRTVPELATLDTRPADSEFPKWAAEAQAAEDAC
                     HRSAGGIRPFVNTANTARDLDVVRAALHEEKINYLGYSYGTYLGAVYGSLFPAHLDRSV
                     LDSAVHPEWIWREQFRAQAVAYRRNVEAWSTWVAEHHDRFALGTTAEAVVGTIETVATT
                     LGQAPVGEQDRTRFDAAVGVGARYRPLWSELAVLVAGLKTGSSSESGALMAGEAREELV
                     SGVFHTVTCEVDWPTDLETYYEDMRIFRDRYPYGFGVMRAAPTTCAFRSFTPPEPAVTL
                     KREGYPVGVVVQAEGDTQTQYESGPAMAERLGHNLVTVRDEGKHGIYGSGNACVDRAVN
                     RYFVDGVLPPSSSTCPGDPRPDVNQVTSAQHVQAYLAGRGLSARF"
     aSDomain        20337..20945
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IOD16_RS04640_Abhydrolase_1.1"
                     /evalue="1.30E-20"
                     /label="IOD16_RS04640_Abhydrolase_1.1"
                     /locus_tag="IOD16_RS04640"
                     /protein_end="287"
                     /protein_start="84"
                     /score="66.0"
                     /tool="antismash"
                     /translation="VLVLNPGGPGGSGLGMPSFLAGSELAKVYDLIGFDPRGVGGSTAL
                     NCRTVPELATLDTRPADSEFPKWAAEAQAAEDACHRSAGGIRPFVNTANTARDLDVVRA
                     ALHEEKINYLGYSYGTYLGAVYGSLFPAHLDRSVLDSAVHPEWIWREQFRAQAVAYRRN
                     VEAWSTWVAEHHDRFALGTTAEAVVGTIETVATTLGQAPV"
     misc_feature    complement(22025..22040)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.24"
                     /tool="antismash"
     misc_feature    complement(22379..22394)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
ORIGIN
        1 ccggtagcag cctgcgcacg gtcgcctcct cttcgtgatc gggtggtgtc cgctggacat
       61 gatgtggcct gggccgccga ggtgcggcgg tgagccgggg tagatcaccc gagagagtgc
      121 gcgaggtcgt cgcgacgccg ggtgacggct tcccggtggg cccaccaccc gatgagcggc
      181 tctacgaagg cacgcgggtg aaaccgggtc gcggcgccgg ctcgctccgg cacgctggga
      241 cgggtgaagg agaagcgccg ggagttggcg ggcctgtgcc gcgtcgcggt ggaccgcccc
      301 aggtggcagc tcgggttcgc ggcggtcgtg tcggcgtggt cgctggcgtg ggtggtgggc
      361 caggcgttcg gcgagccgag cccgctggag gtgctgccgg tgcggtgggc cggcctgccg
      421 accggctggt tggacgcgac gcgcgggtgg ttcgacggcc gcaccgggtt cctggccgtg
      481 gtgggtggtc tgctctgggc gatgacgagc gcgagccgac aggcgtcggc ggtggtcggc
      541 tggctcgcgg tgatggcgtc ggcggaggac gtcggttacg tcgcggtgcg gtgggcgttg
      601 ctgtcgctgg tggtgttcct cgcggtgatg ggcctggtgt cgatcaccgg gcggcgggcg
      661 ttcgtggtgg accgggtggc cgtcatcccg cgggacgtgg cccgcgcggg cgcgacggcg
      721 gcagcgctgt cggcggtggt gccgctggtc gcgccggggc tggtgctggc ccggctggtc
      781 ggcccctacg tgactcggcc accgcgccga cggccgggga cgccgatcgt ccgcgcggct
      841 tccgccgaac ggccgccggc cggcggcaca cccggtgaac tgcccgaacc cgtcccggcg
      901 cagcgcggat cgcgttgagc cggaccggat ttcccgatcc ggtcagggta tgcaaatagt
      961 tttgcacccc aacaaatcta tccgggtaag tcgagtgaac ctcacatcac attctggatt
     1021 cgcctgtttg ggcttaccgg tccgtatcca tcaagatgtg cgagtgccag aaaatcccgc
     1081 cgaaaaccgc ttagccaagg tgatgcgtcg tcagcccgtt cagcagcgcg gcgccgcgac
     1141 ggtgtccgcg attgtcgatg cctgcgcgac gctgctcaac gactacgact acgacgacat
     1201 caccaccgcc cggatcgtcg agctagcagg cgtgccaatt ggatcgttct accaatactt
     1261 cccggacaag cgttctgttg tgcacgcgct ggccctgcgc ggcatggagg agtacctggg
     1321 acgggtggaa acgctgttca cggaggggcg gatcgccgag gactggcggg aagcggtccg
     1381 ccaagtggtc gccgtctacc tgcggatgct cgtcgagatc cccgggttcg ggcgggtgcg
     1441 gttcagcgac ctgctcgacg gccaccgcct cgactcctcc gtcgaccagt acgagctgat
     1501 ggccgagcgg ctgcgggacc tgttcgtgag ccgcttcgcg gtgcgcggcg acgcgccggt
     1561 catgttgacg ttccggatgg ccgcccagac cgcggacgcg atgttcaagc tggccgagcg
     1621 ggtcgatccc gacgaacgcc cggtggtgct ccgcaccgcc gacggggtga tcttgaagat
     1681 gctgtcgacg gtgttcgacc cctcgtgact tgccgcgccg gtcctggtgg tgtggggtgg
     1741 accggtgagc gacgacttcg acgtgatcgt gatcggcggc ggcccggtgg gcgagaacgc
     1801 cgccgcccgg accgccgccg gtggcctgcg gacggcgttg gtggaagccg agcgcgtcgg
     1861 cggcgagtgc tcgtactggg cgtgcatgcc gagcaaggcg ttgctgcgcc cgggccacgc
     1921 gctcgccgcc gcccgccggg tgcccggcgt gccggtcggc gagcggctcg acccggccga
     1981 ggtgctgaag cggcgcaaca gcttcacctc cgactgggac gactcgggtc aggtcgagtg
     2041 ggccgagggc gccgggctga cggtggtgcg cggtcgcggc aggctggcgg gcgagcgccg
     2101 ggtggacgtg gacgggcgcg tgctgaccgc gacgaaggcg gtcgtggtgt gcacgggcag
     2161 cgtgccgcgc atcccgtcgc tgcccggcct ggcggacgtg ccctactgga cgtcccgcga
     2221 ggcgacctcc gcgcaggagg tgccccggtc gctggtggtg ctcggcggcg gcgtggtcgg
     2281 cgtggagatg gcgcaggcct gggcgcggct cggctccgac gtcacgctcg tcgtgtccgg
     2341 tgagcggccg ttgccgaagt tcgaggcgtt cgcgggcgag ctggtcgcgg acgggctgaa
     2401 ggaggacggc gtccggctcg tcaccggggt caaggcggtc ggggtgtcca cttcggacgg
     2461 ctcgggcggc gcgggttcgg gcggtgaggg tttgggtggc tcgggtctgg gtggctcggg
     2521 tctgggtggc tcgggtctgg gtggcgccgg cgaggtgtcg ttgacgttgt cggacgacac
     2581 cgtggtgacc ggtgcccacc tgctgatcgc gaccggtcgt cagccggcga cgttcgacct
     2641 cggcgtggag cagttcggct tcacggcggg cgaggcgctg gaggtcgacg acaccggccg
     2701 ggtgtccgga gtggactggc tgtacgcggc gggcgacgtc acgggtcgcg cgttgctgac
     2761 ccaccagggc aagtacgccg cgcgggcggt cggcacggcg atcgtcaccg gtgcgaccga
     2821 cccggagccg tggaccgcgc cggtcgccac ggccgaccac acggccgtgc cgcaggtggt
     2881 gttcaccgac ccggaggtgg cgtcggtcgg ctggaccgag gcgcaggccc gcgaggcggg
     2941 actggacatc cgggtcgtcg acctcgacat cgcggtggcc ggctcgtccc tgcacgcgga
     3001 cgggtaccgg ggcaaggcgc ggatgatcgt ggacgagcgc aagcgcacgc tcgtcggcgt
     3061 cacgttcgcc ggtccggacg tggccgagct ggtccacgcg gccaccatcg cgatcgtcgg
     3121 cgaggtcacc gtggaccggt tgtggcacgc cgttccggcg taccccacca tcagtgaggt
     3181 gtggttgagg ctgctcgagg cctacggtct ctgacgctga gtgcacgttg tgtcagcaca
     3241 tcgtgtacac catgcgccga gtgccgtatc gaccgtgcgg ccatagagac tcttaacctc
     3301 aaaatgcggc ttcagctcct tacactgcca gtgtgaccag gggaacagtg gccgtcgcga
     3361 tgggcgcggt gctgtggtgc gccttcgtca tcgcctccac gttcctgccc ggcggcccct
     3421 cgtggccgcc ggtcgcggtc cacctgccgg ggttcctgat cgtgccggtc gtgctgcaca
     3481 cgttgttccg cgcgcggtcc agcgcgctgc tgtgcctggc gcacgtgccg aagtcggtgc
     3541 tgttcaccgg gttcgccatc gcggtgggcg ggtggctgtt ctcgttcggc gcgatcgccg
     3601 gcaaaccggg caccgagacg ctgtgcgcgg tggccgggct ggtgatcgtg ctgcacgtgg
     3661 cgttcgggtt gatcggtgtc gggatggtgc gcaccgggcg ttgaccggca ccgtgcgtcg
     3721 gacaggcagg cgtcaagcgt cgaggtgggg gatcacccct gcgcggcggg gagccgcaag
     3781 gcctggtcgg cgatctcggt cagctccggg tcggccgggt cctgctcgcc ctcggcccac
     3841 accacctgcg tgatgcgcag ctgagcgccc ttcgccgaca cgcggatcgc cgaccggtcg
     3901 aacgtcttcg gccctcccgg ccagcccttg ccgtccttga cgagggtggt gacaccgccc
     3961 gagcccgccg ccgacgcgat cgcgtgcagc tcgcttgccc gggtcgagtc gggcaggctc
     4021 agctcggcga tggcgacacc gaccttgcgg ccgtccactg tggtctcgta ctgggcgcgc
     4081 cgcagctgca tgcacaggtg cccggtcagc caaccccgga cgtcgccgaa cgcgtgcgag
     4141 gcgcagtcgt cggtccggtc cgcgccgcgc ggcgagaagt tccggccgtc gacgaccacg
     4201 gtggtcggct gcggggcggt ggtggtggac gtggcgctgt ccgcggtgtc gttcgaggac
     4261 aacgagatga tcagggcgat gaccagcagg agcgccacca ccgcgccggc cgcgtagggc
     4321 aggagcttgc gggcggccgg tgcgggcgtg accttcggca gcagcatcgt gctggcggag
     4381 gccaggtcgg ccgccgcgtc ggagaagccc tcggcgatca ggtgctggcg ggtgggcggc
     4441 gcgccggtcg tggcgaggac ggcgaccagc ttggcggcgt gctcggcgga gcaaggccgg
     4501 tcgctggtgg ccagctcccg cgcggcggcg agcagcgtgg tcggcttcgg gtgcaggacg
     4561 cgcacgccgc ggttcaggtc gacggtcggc tgcacgacct gaccgacgta cgggccgacg
     4621 gccaccaccg tggtgaccgg caacggctcc ccgcgcatgt cctggatgcg gcgggcgacg
     4681 gcggtggtgg cggccagcgc ctcggcggcg gggctcatcg cgccgtccgg ccgggtcagc
     4741 ggccaaccgt cgatcttcca ctggccgttg agcggggcct ccagccgcat ggccgggtcc
     4801 ggcaggtcca cgccgacgac cacgagcaca ccgcgcggca gcacgatcac cgcgtccagc
     4861 tcgcgcgggc tgtccggcgg tcgcacgccg agcagcgcga caccgccgag cacggcgtcg
     4921 ccgttgcccc acgtgctcaa cgcggcgcgc acgtcggcgc ccaccgcgga aggctcggtc
     4981 ccgagtcgga tcagccgcac gggatcacca cgagatcgcg ccgttcggcg gtccacgcgt
     5041 cggcgtgcca cacggtctga cgttcggcgt tccacacggt cggacacggt agcgccgtag
     5101 ggtgacggcc ggtcgggcgc atcgctggag atgacgttgc gtgacagtca tcacctggac
     5161 agcgcgtttg gcgcggtagt tgcgcaaccc cgacgtggag gtcggtggaa gttggtggcg
     5221 gtcgtcgcgg cgaagtggcg gcgatgaggt ggtgacgacc cgccaagatc acgtgaacgt
     5281 ggtcgggtga tcccggaaag tcacccctcg cggcgtggtc tccgcgggtg aggtcgccga
     5341 tttggggtcg aaagtcctgt atctgacccg cccgggtgag gaacgcgatg gttcttatgg
     5401 cggactgctg ccgtagcggg cagaatgacc aagtcgggaa ttcgcaagat cgtccgcatc
     5461 ctcgagaggt cgtaggggaa gacgtccctc gtcgagtagc ggaggtcagc tgtgagcacc
     5521 cgtggcagca gcagtggcgt ggtctacgtc cactcgtcgc cgtctgcggt ctgtccgcac
     5581 gtcgagtggg cgatctcggg caccctcggt gagcgagcgg acctcaagtg ggcggcgcaa
     5641 cccgcggcgc ctggtcagtt gcgcgccgaa tgcaactgga ccggcgacgc cggcaccggt
     5701 gcccgactcg tgtccgcgct cagggcgtgg ccgatgctca ggttcgaggt gacggaagac
     5761 ccgagtccgg gagtggacgg cgtgaggtac tgcttcgcgc ccgtgctggg gttgtggcac
     5821 gcgcgcacga gcgcgaacgg cgacatagtt gtttcagagg accaactccg ggcactggcc
     5881 gcgcgcagca gaggcggcga gtcgttcgcg cacggggtgg acgagatcct gggcgcggct
     5941 tgggacgacg ccctggaacc gttccggcgg gcgggcgacg gtgcgccggt gacgtggttg
     6001 caccgggtgg gatgagcgcg tgcggttgtt cggctaggtg gtcgggtcgg gggcggtgtc
     6061 ttcgctcaag tccggctcga tttgacatgg ggcccgtacg ggcactccag gcaggccaaa
     6121 gccggcaggc ccggcgggga agagcgtccc gccaggcctg ccggcttcga ccagcctaaa
     6181 gcacccgaac ccatgtcaaa tcgggccttt gtgggtggtt gcggggctgt ggtgggtggg
     6241 tcgtgtcagg tgcccacacc gccgccaacg gtcgggatca ttcctccgat ccgtcaccgc
     6301 gtaggcgttc ggcttcgcca ggtcggggtg agatcgcgcg gcgggctcgg ggggtctgct
     6361 agggcgcgat cggggtgggt tgccaggcgg ccatgaggtc ccggtagagg ggtgagtcgg
     6421 ccaggaggtc ctggtggctg ccgagcagtg gcgggccgcc gtccatgagg aggaccaggt
     6481 cggctcgcag cgccgaggag agccggtggg cgatcacgat cagggtgccg cccctggcgg
     6541 cgaatgcctg ctccaccacg gcttcggcgg aggggtcgag ggctgaggcg gcctcgtcca
     6601 ggatcaccac gtcggccggt gaggcgtgga cgcgggcggc ggccaggagt tgggcctcgc
     6661 cggcggagag accgcccccc gcgtggccca cggagccggc caggccgccc agcctggtga
     6721 tcacgtcggt cgcgccgacg gcctcggcgg cggacagcag cgcggcgtcc ggggcggccg
     6781 gggcgaacaa ggccaggttc tcgcggacgg tgccggtgaa caggtaggtc tcctggggga
     6841 ccagggcgat ccgctcgtgg cgcacccccg gcgcgacgga gcgcaccggg acaccgccga
     6901 agcgcacgac accggcctgc ggttccacca tgcccgtgat cagaccggcc aacgtggact
     6961 tgccgatgcc gctcgggccg atcaccgcca ggtgggcgcc ctcgggcagg acgaggtcca
     7021 aggagcgcac gacgggttcg gccgtggcgc tccagccgaa cgtcacgccg ctcagctcga
     7081 tctcgcggcc ctcgggcacg gcgtcgccgc cgggcacgtc gaccggtggc gcggcctccg
     7141 ccagccggcg cagggccacg accagccgca gcacgatggt gctcgtcgtg tccgccagcc
     7201 ggcgcagggc gggctgcacg ctggtgctca ggtagaccac ggcacccagg acctcgccga
     7261 ccgacaacgt gccggcccga accatccccg gcgccacgag cagcagcagc acgagtggcg
     7321 cgaagccgcc cagcgcgatg accacgccgc gcaacgccgt ggcgcacgcc atccgcacgg
     7381 tcgccgacgc ttgccggttc acctgctcca tcacgtcgtg cagtgcctgc tccgaaccgc
     7441 cgacggccac cacgtcccgc atgccgagca acaccgtgcc ggccaccgcc gccgactcct
     7501 cgtcggccag caccagccgc cgctggccgc gcgccaacga cggcagcagc agaccgaaca
     7561 gcacgagtgc cgccaccacc ggcaggatca ccagccacgc caacgacgac accgtgaccg
     7621 ccagcccgac cagcgccgcc gccgtcgtca cgagcagtgc ccgcgcctgc accagcacac
     7681 cggcggtggc gtcgcgcacc acctcgacgt gccgggtgat ccgggcgacc gcgctcgcgt
     7741 ccggctgccg ggtctgcgaa ccaccgtgca gcacaccgcg cacgacctgg cgcaccaggg
     7801 cgtcccgcaa cggctcgacc accgcaccga gccgcatgaa cacctgccgc agcccgaacc
     7861 cgccgagcac cgcgaccgcg gcgaacagca gcagccaccc gacgccgacc cagggcctgc
     7921 cggccccgaa accccggtcc accgccaacc cgaccaaccg gccggacagc agcgcgggca
     7981 ccccttccaa caccgaccag ccgagcagca cgacgatgcc gcgccgttgt tcgcgcaacg
     8041 cccgcaggta cgtcatcagc cgaacaccgc ccggtactcg tcgtcgtccc acagctcgga
     8101 gtgcggcccc accgcgcgca cccggccccc gtccaaccac accacgacgt ccgccctccg
     8161 cgcggtggcc gcgcgatgcg tcaccacgac ccgcgtccga ccgggcaacg ccgactcgac
     8221 cgcacgttcg acggtggact ccgtcaccat gtcgaggctc gccgtggcgt cgtccagcac
     8281 cagcaccgcc gggtcgcgca cgaacgcgcg cgccaatccg agccgctgcg cctcaccacc
     8341 ggacatcggc gccgccgaca tcggggtgtc gtagccctcg ggcagccgca ccaccacgtc
     8401 gtgcacctgc gcggcacggc aggcggcctc cacctcgtcg tgatcacggg acgtgccgta
     8461 gcgcaccgcg tcgccgacag tcgtgccgac gagggagggt cgctcgaacg cgtagccgac
     8521 ggacccgccg cgccgcaccc gtccggtgga cggccgggtc agcccgccga tcaccgacgc
     8581 gagcgcggac ttgcccgacc cggaccggcc gaccacggcc acgaacgtcc cggcggccac
     8641 ggtcagctcg acgtcgtgca gcgcgccggg cacgttcacg ccggtcagca ccagttcacc
     8701 ggtcgccgcg ccgcccggag cgtcttcggc gggcacgggt gtcgacagca cttcgtccag
     8761 ccgttgcgca gacgcccgtg cgcgctggat ggcggtcaac agggtggcct ggccgaccac
     8821 ggtcatcccg agcgccacgt acccgagggt ggccagcacg tcaccgacgc tcaaccggcc
     8881 cgcgaccacg ccgaaaccgg cggcggtcag gacggcgagc tccacggcgg gcagcaggag
     8941 accggcccgc cagatcatcc gcgcctgcgt gctccacatg ccgacaccgg cggcggccag
     9001 gcgggggagc gggcgcagga cgcgttcggc ttcttggtcg gcacgtccgg aggcggcgat
     9061 ggtgcgcagg ccgccgacgg cgtccaccag tcgtgcggac aactcgccgg acacctcctg
     9121 gtaagtggcc acgtccgcgg ccgtcagccg caggtgcgag cggaccagca aggccgccag
     9181 ggggacgctc agcaggaaca cgaccgcgag ccgccagtcc agcagcgcca acgcggtgat
     9241 cgcgccggcg gcggtgacca ccgagatgcc caggttcacc gccagcaccg agacaccgcc
     9301 cgcgatcgcg ctgtcaccgg tcagccggct caccgcgtca ccgggctcga accgcgtcgg
     9361 gtggcccaac gccaccaggt gggcggtcaa ccggcgccgc agccacgtcg cgccgctcgc
     9421 ggtgatcgcc gcggccagca ccacgccgat cgcgtcgccg aggacttcca cgcccgcgag
     9481 ccccaccagc cacaacaccg tgccgcggtc cagccgcccg gccagcgcca tgtccacggc
     9541 cgaggccagc gcggtgggca ggaggagtcc ggcggtcgtg gccggcagcg cgttcagcgc
     9601 cagcagcagc cagcggggat ctcgccgcac gacagaagag agcaccatgc tttgggactc
     9661 ctatgacggt tgccgcggtc gggcgcatca tgtgtcgggg gtccgacggc atgccgtcgg
     9721 acccccgatg accgggtgag cggcgcactt cgactgcgcc gctcacccgg ggtgcagctg
     9781 agctgcgagt cggactagca gatcacgagg ctcacggtgg agtgggcgcc gcagcccagc
     9841 agggacaggc ccgaggcgga cgtgctgccg ccgccgccgc tgctgctgcc acccgacgcc
     9901 atcgcgttgg aagcggcctc gggggtctcc atgtcctgca ggtcgaggat gaagtccatg
     9961 gtggtgactc cttattcggg ggattggatt cggggtactg ctaccgaccc gcgagggtcg
    10021 gggctttgag gaacggcagc atcggggtgc cgttcgcgag ggtgccgagc gccaggagca
    10081 cgcccgcccc gccggtgttc aggtccatcg acaaccgccg cagctggatg ccggggaacg
    10141 ccagtccgcc ctggtagggg atggcgtgcc aggcgagcga ggccaggtgc cggtcgatcg
    10201 cgtgcccggg tccaccggtg tgcacgagcg tggccagcag accggcccgg cccagcatca
    10261 gcgcgggctg gatgacgaac tcgccggtcg tggcgctgag cagctccggc agcttgtcca
    10321 gcaccggcag gtccggttcc accaggcgga actcgttgag caccagggcg attcccgcgc
    10381 tgccggtgcc gacgtagggc agggtgcggg cgctgccgtc ccggacctgc gtcgaaccgt
    10441 ccagcgcgat catcgtctcg gccaggtcgc gctccagcgc cttgacgccc acgtccagcc
    10501 agcgccggtc gccggtgcgc tcgaacaggc gcaggaacag cagcgcggga ccggaccagc
    10561 cgtgctccag gcccgcgcgg gctttgtcgc cgggcggctc gacgttcgcc agcgcggtgt
    10621 ccaggcgctc ggcgagctcc agcgcctgct cggcgtaggt ctcgtcgtcg cgcgtgccgg
    10681 cgaagtgcag caggttgagc gcgatgcccg cgaggccgga gccgaggccg tggtcctcgg
    10741 tgtcgggcac catcgcggcg taggagcgga ccagctcgcc cgcgaggtcg tggtggccga
    10801 actcctccag cacgtacgcg atgccgtggg cgccgctgaa gaagccgggc tccttcggcg
    10861 ggtcgcggcg cacggcctcc agcagccacc gctcgtggtc ggggaaccgg ccctgacccg
    10921 tgacgtccag cgcgtgcagc acacccgccg cgccgtagcc gaaggtggcg ccgccggtct
    10981 cgaactgctc cacgtcaccg gggaacagcc ggtcgtcgcg ctgcggggtg gcgctggcca
    11041 ggatcgcggc cgcgaccatc ttgagcaccg ccggcagctc cggctccggc gcgtccagcg
    11101 cggtcgtggg cgactcggtc ggcgggtcga cgcggcgctc caggccggcg aggatcttcg
    11161 cgcagtactc ctcggacagg ccgaaccggc gccggatgaa gtcgacgtgg gactgcagct
    11221 tcaccggcgc gagttcgagc atggtgatga gcggcaggaa gacgtacagg cgcagcgcgg
    11281 cgagggcgtg ctcgtcgatc tcgaagccgc tgcggtccgg cggcgcctgg aagcccggcg
    11341 agccgagcgt gggcttcttg tcctcctcga cccggaacgc cagctcgaag tcgatcagcg
    11401 agatcgagtc gtcgtcgtcc accaggatgt tgagcgggtg gaggtcgcag aacaccaggc
    11461 cgcgggcgtg cacgtcgccg atgatccgct cgaccgcggc gatgaccttc agcgcgcgct
    11521 cggtgtaggc ggcgaccgcc tcgtcggaga tctcgtggtg ggtgagcggg tagtgctgcc
    11581 cgagccactg gccgagcggg cggcccggta cctcggacat ggccatgaac tcgtgctccc
    11641 acgcgctgaa gcgctcgaac acctcgggca cgcccgggac gcccgcgacc ttctccagca
    11701 tctcgtgctc gcggtgcaac cgggcgaccg cgtcgacgtt cagccggtcc aggcccgagt
    11761 gcggtctggc ctccttgagc accacccgct ggtcgtcgga cttgcggatc gcctcgtaca
    11821 cgccgccgcc gttggagaag tgcagtgagc ggagcacccg gtacgggaac tcgtccgcgc
    11881 tgcccgcccg gcgcacggcc aggtgctcct ccaggcacgc cgggatcttc acccactcgg
    11941 gcgtccagaa agtcggcttg cgctggtcgg gcacgagtgc gccgtccggg ccctcgatgg
    12001 ccagcacgcg cttgccgtcc ttctccagcc actgctcgac gaacccgccg tagcggacga
    12061 acaacgggcc ggcgccgtag cggaggtcgc tcaggatgta ggcgcccgac tggcccttga
    12121 ggatttcgga caactcgcgg agcgtcgact ccagctcgga atcgtcggcc gggtagatcg
    12181 tgatgagctt gccgctgccc tcgcgaggcg cgtacttcga gttgcgggcc agcacgatgg
    12241 accgggtgcg caggtacttg aacgggatcc ggcgggcgac caggtactcg taggacttca
    12301 gcagtacctc gccggcgttc agcacggtcg ccgacacgtg gatcttccag ccctgcttcg
    12361 gcaggggaac gccctgcggg taggtgtgcc gccagatgtt gcggtcaccc tgggcccatc
    12421 cttccggcaa cgcggggaga acttgcgaga aatcgtcttc ggaggtttcc gtgctgcttt
    12481 gcacgtcata gaacagacga tccgcgaagc agtaggcctc atagcggagg tccacgggat
    12541 ttcgcctcct tgcgatttgt tcgaccgggt tattcccgca cgtccacggt ggagaagcca
    12601 atccaccatt tcggggggtg ttgacgtcca ttcgtgcgag cgaggatccc tcggatttgc
    12661 actgctggta cgtatagggg cctgcagagt cacccgatcg cgatgtttgg ccgcaccgta
    12721 gaggggacag cgactaccgg aggagcctaa acgaaacgcg atcgttcttc gcgttcgacc
    12781 gtgctcacct gcgggttcgc aggtttcccg ctgaattgcg ggttcggtca cggacggtgt
    12841 cgaaaagcct ggtgagcggc ggtcccgacg tttcgggacc gcttcgggcc cggtattgcg
    12901 gaaaaggatg ccggccatcc ttgatggcca ttgtgggtag tcggatcggc ctgcggaaac
    12961 cgcatggtgc gggtcaaccg ctgggccgtc cgggtgatta tcggtccgta tgggcgctgt
    13021 ggcacgctcc tggggtgtcc gcacgcctgc tgctgcccgc cgtgctcctg gtcgccgccg
    13081 cgacggccgg ggtcggcgtg ctggcgcgtg aggcctacca acgacccgtc gtgccgccgg
    13141 gcggccaggt cgcggcgccc ggttccgggc agtccggttc ggtgccgcgc agcgcccagc
    13201 cgggcagcgg cgcggtgcag ctgagcgtcg acgcggcgca gcacccggac ggccaacgcg
    13261 tgcgcgaggt gctccagcag ttcttcgacg cgatcaacga ccacgactac gagcagtggg
    13321 ccaagaccgt gaccgcgcac cgggtcggcc agacgccgag gtcgcggtgg ctgtcggact
    13381 acgagagctc gcgggacggg tcgatcctgg tgcaccggat cgagtcggtg tcggagagca
    13441 ggctgcgggt gctgatgacg ttcaccagca cccaggacgt cgtcaaggcg ccggcggagc
    13501 tgcaggccga ctgcatccac tggcgcgtgg tctatccgtt gcaggtggac cgcggcacgc
    13561 tccgcgtcga cctgggcacc gagggctcga cctcccagtt caccgcctgc tgacgcaccc
    13621 gacggcccac ttcacccggc cccggacgcg gcggtggggt cgccccccga ctccagcgac
    13681 cccaccgggg aacccgccta cagcgggatg ttgccgtgcg cgccccggcc cgccggcgcc
    13741 gccgcgaggg cctgcgccag cttccgccgc gtccgggtcg gctcgatgac ctcgtccacc
    13801 acgccgatcg cgaccgcccg ctccacgccg cccgcgatcc gctcgtgctc ctcgacgagc
    13861 tgggcgtgca acgcctcgcg ctcctcgtcc ggcacggcgg ccagcttctt gcggtgcagg
    13921 atgccgaccg cggccttggc gcccatcacg gccacctcgg cgatcggcca cgcgaacacc
    13981 gccgtcgcgc ccaacgaccg cgagttcatc gcgatgtacg cgccgccgta cgacttgcgc
    14041 gtcaccaacg tcacccgcgg cacgaccgcc tcgccgaacg cgtgcagcag cttcgcgccg
    14101 cgccgcacca cgccgtccca ctcctggccg acgcccggca ggtaccccgg cacgtccacc
    14161 agcaccagca gcggcacgcc gaacgcgtcg cacatccgca cgaaccgcgc cgccttctcc
    14221 gccgacagcg agtcgaggca cccgcccttg cggatcgggt tgttcgcgat cacgccgacc
    14281 gtgcgcccgc cgagccggcc gaggccgacc acgacgttcg gcgcccactt ggcctgaagc
    14341 tcctcgaacg agtcgtcgtc caggatcgcc cgcaccagcg gcttgacgtc gtaggcccgc
    14401 tgcggctgct ccggcagcaa cgcccgcagg tcgtcgccgt cgggcaccga gtgcaggtcg
    14461 aacacaccgg gctgggcgaa cagcccggtg atccgccgcg cccgctcgta ggcgtccggc
    14521 tcgtcgtccg cgaccacgtg cacgacaccg gacttgcgcc cgtgcgcctc cgcgccgccg
    14581 agcccgtcca tgtcgatctg ctcgccggtc accgaccgga ccacgtccgg cccggtcacg
    14641 aagaccttgc cggccggagc catgatcacc acgtcggtca gcgccgggcc gtacgcgccg
    14701 ccgccggccg ccgggccgac caccacggag atctgcggca cccggccgga cgcccggatc
    14761 atcgcggcga acatctggcc catgccgtcc agcgactcca cgccctccgg cagccgcgcg
    14821 ccgccggagt gccagacgcc gatcaccggt gtgcgctcgc gcaccgcgac gtcgatcgcc
    14881 tcgacgatgt gccggcaccc ctccgagccc agcgcgccgc ccatccgcgt ggcgtcgctg
    14941 cagtacgcga cgaccttcgc gccgttgatc cggccgcgca cggcgaacat gccgctcccg
    15001 tcgcggggtc gcagcggcgc gacggacccc gggtcgagca gctgcgcgag ccggacctcc
    15061 gggtcgcgcg ggtcgggttc gccgtccgcg gccgggttca ccggtcggga cgcaaggacg
    15121 gtcatcgggg tgctcctcgt gggacggtcc ggtccgggat gatcaggctc cggtgaagac
    15181 gagcgagacg ttgtgcccgc cgaacccgaa cgagttgttc accgcggcgg tcagctcgat
    15241 cttgcgcggc tcaccggtca cgacctccag ctgcaccctc gggtcctggt cgtccaggtt
    15301 cagcgtcggc ggcacgatgc cgtcgcggac cgacagcagc gtggtgatcg cctccaccgc
    15361 gcccgaggcg ccgagcaggt ggccgtggtt gcccttgggc gcggtcagca ccgggtggtc
    15421 gccgatcgcc cggcgcacgg cctgcggctc gatcacgtcg cccaccgggg tggacgtcgc
    15481 gtggcagttg acgtggccga cgtcggccgg gtccacgtcc gcgctgcgca gcgccttggt
    15541 gatggcccgg gactggccga ggccctccgg gtccgccgcg gtgatgtggt agccgtcgga
    15601 cgtggtgccg atgcccgcga gcttgccgta gatccgcgcg ccgcgggcgc gggcgaagtc
    15661 ctcgcgctcc agcaccagga tcccggcgcc ctcgccgagc acgaacccgt cccggttgac
    15721 gtcgaacggg cgcgacgcgc gttccgggtc gtcgttgcgg gtgctcatgg tccgggcctg
    15781 gatgaagccc gccatggtga tggtggtgat gcacgcttcc gcgccaccgg ccacgaccac
    15841 gtccgcctcg ccggtcttga tcatccgcca ggcccaggcc agcgcctcgg cgccggacgc
    15901 gcaggccgac accggcgcgt gcacgcccgc gcgtgccttc aggtccaggc cgacgtgcgc
    15961 ggccgggccg ttgggcatga gcatcggcac ggtcagcggc gagaccttgc gcaggccgga
    16021 cgcctcgatc aggtcgtcct ggtccagcag cgtcatggcg ccgccgatgc cggtgccgat
    16081 cacgacaccc agccgctcca ggtccacgtc gtcctcgccg agccccgagt ccgcccaggc
    16141 ctggcgggcg gcgaccaccg cgacctgctc gcagcggtcc aaccggcgcg cctcgacgcg
    16201 cggcagcacc tcggtcggct cgaccgcgag ccgcgcggcg atccgcacgg gcagctcgaa
    16261 ccgctccgcg aagccgccga ccagcggcgt cacgccgctg cggccggcca ggagcgcatc
    16321 ccaggtggag gcgacatcgc caccgagcgg ggtggtggca cccagcccgg tgacgacgac
    16381 gtcgttgtta ctggtcatgc gttgctggcg atgtagttga ccgcatcgcc cacggtcttg
    16441 aggttggcca gctcgtcgtc cgggatcttc acgccgaact tgtcctcggc ctgcacggcg
    16501 atctccacca tggacagcga gtcgatgtcc aggtcgtcca caaaggactt gtcagccgtc
    16561 acgtcggccg cctcgacacc ggcgacctcc tcgacgatct cggcgagccc cttctggatg
    16621 tcctcgttgc tcactgaaaa tcccttccct cttgcttcgc cggccgggtg gtcccgccgg
    16681 agtctggaat tgcggtcacg gcagccggac gacctgtccc gcgtaggaca ggcccgcccc
    16741 gaagccgacg agcagcgcca cgtcgccgct gcgcacctct cccgccgcgc gcatgtggtc
    16801 cagcgcgagg gggatcgaag cggacgaggt gttgccggag tccacgatgt cacgggcgat
    16861 cacgaggtct tcacgcgcac ccttggcgcg caaccgcttc gcgatggcct cgatgatgcg
    16921 caggttcgcc tggtgcggca cgaagacgtc cacatcggac acctcgatgc cggccagctc
    16981 gatcgccttg agcgcgatcg gcgcgatctg cgtggtcgcc cagcggaaga ccgactggcc
    17041 ctcctggaag atggacgacg cccggtcctt gatgtggatc atgtccacga ggtcgcccgc
    17101 gctgccccac gacaccgggc cgatgccggg ctcgtcggac tgccccacga ccgccgcgcc
    17161 cgcgccgtcg gcgaagatga tcgcggtgga ccggtcgtcg gggtcgaccc agtcggtcag
    17221 cttctccgcg ccgatgacca gcacgttctt cgccgtgccc gcccggacca ggtccgaggc
    17281 ggtgcccagg gcgtagcaga agccggcgca cgcggcgttc atgtcgaacg cggccgcgcc
    17341 cgtgatcccg atccggtggg cgacctgcgc cgccgcgttg gggatctggg acggcatggt
    17401 gcaggtggcc acgatgaccg cgccgatgtc cgacggggtc agcccggcgt cggccacggc
    17461 cttgaggccc gcttcgatcg ccatgtccac cagcagctcg tccggcttgg ccacgcggcg
    17521 gttggcgatg cccacccggt cgcggatcca ctcgtccgag gtgtccatgc gcaggctcag
    17581 gtcgtggttg ctgacgatcg tctcgggctg gtagctgccc atgcccagga tgcgggtgcc
    17641 ggccgggccg gccggcgtcg agaaggtggt cactcggcca cctccgacgg tgtcgcggtg
    17701 atcatctcga cgacctggtc gagctggtcg ggggtcttga ggcccaaggt gggtgtgccc
    17761 ttcagttcgc gcttggccaa gccggtcagc gcgcccgccg gcggcagttc gaccaccgcg
    17821 gtcacgccgt gcccggccag ggttgcctgg caggcgtccc accgcaccgg gcgggtcacc
    17881 tgggagatca gtcggctcag cacctcgtcg ccgtcggaca ccagcgcgcc gtcggcgttg
    17941 gacagcagcg gcagcgcggc gtccttcacc acgatcccgg cggcacgggc gcgcaacgcg
    18001 tcctcggcgg gggccatgaa ccgggtgtgg aacgcgcccg cgaccttcag cgtgcggatc
    18061 ttcgcccggg tgggcggctg ctcgaccagg gcggccaggg cgtccaccgg gcccgcggcc
    18121 acgatctggc ccgcgccgtt gcggttcgcg ccgaccaggc cgagctcgtc gagccgggcc
    18181 agcacctcgt cctcctcgcc gccgagcacc gcggccatgc cggtcggcgc caaggcgcac
    18241 gcggcggcca tctcggcgcc gcgcacggcg gcgagcgaca cggcgtcgtc cgcgctcagc
    18301 acaccggcga tcgcggcggc ggccagttcg ccgaccgagt ggccgccgac gaccgtgtcc
    18361 gcgggcagct ccacccggcg gcgcagctcc tcgtaggcca gcagggcaag cgcgaccacc
    18421 agcggctggg tgacggcggt gtccttgatc tcgtccgcgt ccgccgtggt gcccagccgg
    18481 gccaggtcga gaccggtcgc ctcggaccac gcggccacgc gctcggcggc cccctcgacc
    18541 tcgagccagg gggtgagcat gccgggtgtc tgggacccct gtccgggggc gaggagcgcg
    18601 atcacccgct cactgaacac ggtcgcggcc gttcgcggtg atgtcgccac tgacgaaacc
    18661 ggggacgctg gcttgtaggg ttcctacaaa tgtgactcgt agatgaacgt agaacgacgg
    18721 cgcgtgttgt cgatgccgac ccaatcggac atgcgttgtc cgtcacactc ggtcgagggt
    18781 cgtccactca ggtcaccaca gaccgcgggc gcgggccagc ctccccacgg agagcgccac
    18841 ccgcagtacc agagcgtcac gggggtcgtt ggcgttgcgc ccggtcaact ccgtggcgcg
    18901 cttgagccgg tagcggaccg tgttcgggtg cacgaacagc ttgcgcgcgc acgcctccag
    18961 caccccgccg acttccagga acgcgtccac ggtttccagc agcgagccgc tcgcctcctc
    19021 cagtggccgg gccacccggt ccaccagctg ccactcggcc tccgggtcgc ccgccagcgc
    19081 ccgttccggc agcaggtcga gcgaccgcac gggccgcggc gcggcgggcc accccacgac
    19141 cgcccgcagc ccggacagcg cgtcgctggc gctgcggtgg gcttcggcca ggctcgtcac
    19201 ggtcggaccg gcgaccaccg ggccgggccc gaacgcgtcg gacagccgga ccagcgactc
    19261 gctgcggtcg gtctccccgc cgagcaccac caccagccgc gagccctgca cgctcagcag
    19321 caccggccgg ccgacccggg cggcccggct gcgcacctcg aagaccaccg ccggcgggtc
    19381 gtccgacggc gggttgccca ccagcacggt cgcctccgcg gcggggtccc agcccagcgc
    19441 ggtggcccgc gacagcaacg actcctccgc atcaccacgc acgatgccgt ccacgaccag
    19501 cgcctccagc cgggcgtccc acgcgccgcg cgcctcggcc gccgccgcgt acgacgtggc
    19561 ggcggagaac gcgatctccc gcccgtaccg cagcacgccc tcggtcagca acgcccgctc
    19621 ggcctcgttc tcggccagct tgggcagcag ctgctcgaac agctccagcg cgatccgcac
    19681 cagctccacg gtctgccgca ggctcaccca ccgcgagatg tccttgggcg cggagcggaa
    19741 cgcctcggcg gtcagccgga tcgcctgctg cgggtcgtgc agccaggaca cgaacccgga
    19801 caccccgttc tggatcagca gcagcacccc ggcccgctgg tcggcgggca tccgccggaa
    19861 ccacggcagg cgctcctcca tctcggccac gctcgccgcg gccaggtcgc ccgacgcccg
    19921 acgcagcgtt cgcaaggtgg cccgcgacaa cgcggttgag ctggtcatac ccccacgatc
    19981 gcacgggccc tcaggcgcgc caccaacgag tgacacgcac tgacgctccg cgccgatccg
    20041 cttaccgtcg gtggcattct gaccggctcg cctgggaggg tctcgtgcgc aggttcatgt
    20101 cagtcggcct ggtggtcacc gcggtgctgg cgacggcggt cgccccgtcg ttcggaacgg
    20161 cgcgcagcga tccgctggcc gagttccaca cgcagcagct cacctggtcg ccgtgcaagc
    20221 agctgctgga gtgcgccgaa ctggtgctcc cgctggacta ccgcaggccc ggcgccgacc
    20281 ggatatccct ggtcatcagc cggaagaagg ccacggacac cgctcggcgg cgcggcgtcc
    20341 tcgtgctcaa cccgggcggt ccgggcggct cgggcctcgg catgccgtcg ttcctggccg
    20401 gcagcgagct ggcgaaggtg tacgacctga tcgggttcga cccgcgcggc gtcggcgggt
    20461 cgaccgcgct gaactgccgc acggtccccg aactggccac cctggacacc cgaccggctg
    20521 attccgagtt cccgaagtgg gccgcggagg cgcaggccgc cgaggacgcc tgccaccgct
    20581 ccgccggcgg catccggccg ttcgtcaaca ccgccaacac cgcgcgcgac ctcgacgtgg
    20641 tgcgggccgc gctgcacgag gagaagatca actacctggg ctactcctac ggcacctacc
    20701 tgggcgcggt gtacggcagc ctgttcccgg cccacctcga ccgcagcgtg ctcgactcgg
    20761 ccgtgcaccc ggagtggatc tggcgcgagc agttccgggc gcaggcggtg gcctaccggc
    20821 gcaacgtcga ggcgtggtcc acctgggtcg ccgagcacca cgaccggttc gcgctcggca
    20881 cgaccgccga ggcggtggtc ggcacgatcg agacggtcgc gacgaccctc ggccaggcgc
    20941 cggtcggcga gcaggaccgg acccgcttcg acgcggccgt cggcgtgggc gcccggtacc
    21001 gtccactgtg gtcggagctc gcggtgctgg tggccgggct gaagacgggc tcgtcgtccg
    21061 agtccggcgc gctgatggcc ggcgaggcgc gggaagagct ggtctccggc gtgttccaca
    21121 cggtgacgtg cgaggtcgac tggccgaccg acctggagac gtactacgag gacatgagga
    21181 tcttccgcga ccgctacccg tacggcttcg gcgtcatgcg cgcggcgccg acgacgtgcg
    21241 cgttccgcag cttcacgccg ccggagcccg ccgtcacgct caagcgggag gggtaccccg
    21301 tcggggtggt cgtgcaggcg gagggcgaca cccagaccca gtacgagagc gggccggcca
    21361 tggcggaacg gctcgggcac aacctggtca ccgtgcggga cgagggcaag cacggcatct
    21421 acggcagcgg caacgcgtgc gtggaccggg ccgtcaaccg gtacttcgtc gacggcgtgc
    21481 tgccgcccag cagctccacc tgccccggcg acccgaggcc ggacgtgaac caggtgacct
    21541 cggcgcagca cgtgcaggcc tacctcgcgg gccggggcct gtccgcccgg ttctgacttc
    21601 cggggcacca cgcgaaaacg cccggcgcgg attcctccgc gccgggcgtt tccctctccc
    21661 cggtccccac cggtgattcc actctggact gccgacgcga gaaccgccac gtcagtcacc
    21721 ctttcgtgcc acgacttcag gttgccgggt gatgcgggct gagaaacgat cccgaccaca
    21781 agcgaactgc gaaggagggt cgtcgtgggt acccagatca ccgaaggact cggacaggcg
    21841 tgggcgatgg tggccacgtt cgtgccgaaa ctcctcggct tcctcgtcgt gctgctcatc
    21901 ggttggctga tcgcgaaggc gttggccaag gcggtcggtt tcctgctcaa gcgggtcggt
    21961 ttcgaccggc tcgtcgagcg ctccggcctg ggcggcgcga tgtcgaagtc cccgatcgac
    22021 gcctccaacc tgatcgtcaa gctggtgtac tacttcgtgc tgctgatcgc cctgcagctc
    22081 gcgttcggcg tgttcggcac cgggaacgcg gtgagcaccc tgctcaacga cgtcatcgcg
    22141 tacctgccgc gcatcgtggt cgccatcgtg ctggtgctcg tcgccgccgc gatcggcaag
    22201 gcgctcaagg gcctggtgac cggcgcgctg ggcaaccgcc cgtacacgcg ggtcctgggc
    22261 aacatcacct acggcttcat cgtcgcgctc ggcgtcatcg ccgcgctcaa ccagctcggc
    22321 atcgccgtcg cggtcaccct gccggtcctc atcaccgtgc tggccacggt cgccggcgtg
    22381 atcgtgatcg gcgtcggcgg cggtctggtc cgcccgatgc agcagcgctg ggagggctgg
    22441 ctcaaccgca tccaggagga gtcggcgcac atcgcgcccg cgccgcgcca gtcccaggac
    22501 ccgatgacga gccgggcgca ggagccggtg acggc
//
