LOCUS       NZ_CP067993            20879 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain DHHJ chromosome, complete
            genome.
ACCESSION   NZ_CP067993
VERSION     NZ_CP067993.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4682909)
  AUTHORS   Cao,Z.-J.
  TITLE     Genome Characterization of a novel Stenotrophomonas isolate with
            high keratinase activity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4682909)
  AUTHORS   Cao,Z.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2021) Bioengineering Department, Donghua
            University, North People Road, Shanghai 201620, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 336.0x
            Sequencing Technology             :: PacBio RSII; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016659185.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:56:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,314
            CDSs (total)                      :: 4,222
            Genes (coding)                    :: 4,196
            CDSs (with protein)               :: 4,196
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 10 of 26
            Pseudo Genes (incomplete)         :: 16 of 26
            Pseudo Genes (internal stop)      :: 0 of 26
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:47:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3312255
            Orig. end                         :: 3333134
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067993.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang-Jun Cao.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20879
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10879](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10879
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(339..1583)
                     /locus_tag="JJL50_RS15525"
                     /old_locus_tag="JJL50_15525"
     CDS             complement(339..1583)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410514.1"
                     /locus_tag="JJL50_RS15525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15525"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_180845106.1"
                     /transl_table=11
                     /translation="MVDLPDGRPVNAASPSLQPVASGERIAVLDVLRGAALLGILLMNI
                     EAFSGPLDLAFTGIDVHWQGIDYWADAFVYVFVQGKFFTLFSLLFGAGFAVMAQRAEAA
                     GRDFTPFYLRRSAGLLLIGLCHALLVWSGDILVMYALISLPLLACREAPRSWLPWMGLM
                     VYLGGVAMMLLVGAMVSMASAEDVQGMLAEAQRSIELQRQVYGQGSWAQANVQRLSEFG
                     TSMGALLITGPEVLGMFLIGSWFAGSGALATPERFPRLYASLRWIALPLGLLVTLLGVA
                     WKPYLAPGAYNLPVTAAMAMVTVGGLPMCLGYLAWIVHWRMRLAWLAPVGRMALTHYLA
                     QSLVCTLLFYHYGLGWFEVMPRSVQLLFALLLFAVQVGISHAWLRRFRFGPMEWLWRAM
                     TYRQWPPMRRGAGQG"
     gene            complement(1683..2165)
                     /locus_tag="JJL50_RS15530"
                     /old_locus_tag="JJL50_15530"
     CDS             complement(1683..2165)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418041.1"
                     /locus_tag="JJL50_RS15530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15530"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_049398704.1"
                     /transl_table=11
                     /translation="MKIEKDRVVRFHYTVSEVGQEPIESSKDRGEPLAILIGHGNIIPG
                     LENAMMDKEAGATFSVDVNAADAYGERREGLSQRVPKKHFGNTKLAPGQQVVLQTNFGP
                     RAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVDVREAGKEEIDHGHVHGDGGHQH"
     gene            2239..2817
                     /locus_tag="JJL50_RS15535"
                     /old_locus_tag="JJL50_15535"
     CDS             2239..2817
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005414114.1"
                     /locus_tag="JJL50_RS15535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15535"
                     /product="C40 family peptidase"
                     /protein_id="WP_065428014.1"
                     /transl_table=11
                     /translation="MTANPKVAHYPEIMHITPVSSGLRRLLAPALLLALPVLMTACGGG
                     KATRPAPPPPTANWPKTVPDNPEAANSVLMRAISLVGTPYRYGGNTPDSGFDCSGLVAY
                     VYREMLDLKLPRTSRDLAAVQGPKIDPQRLATGDLVFFGSRGSVTHVGIYVGEGRFVHA
                     PSTGGTVRLDSLSGPYWKDHYTGAKRVLR"
     misc_feature    complement(2843..2858)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    2884..2897
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.46"
                     /tool="antismash"
     misc_feature    2926..2935
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    complement(2938..2953)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            3015..3722
                     /locus_tag="JJL50_RS15540"
                     /old_locus_tag="JJL50_15540"
     CDS             3015..3722
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003475603.1"
                     /locus_tag="JJL50_RS15540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15540"
                     /product="C40 family peptidase"
                     /protein_id="WP_223224737.1"
                     /transl_table=11
                     /translation="MLGLALCLTSLPAWSQTAPNRSDVTPAPVAESTARPAAKAEAAAP
                     QRSRVDAAASATLAALLPHLAANDTIPLMDRSAVVAGDLSRLLANYDTSSAANGSVVGT
                     AADNGKVQSLLRRAMTLLGTPYRWGGSNPDSGFDCSGLVGYVFRSALGIELPRVSREMA
                     HDDNAELINDRTALAAGDLVFFGRKGRVDHVGIYVGDGRFLHAPSSGKDVRVDTLLSGY
                     WGNKFMQARRVDL"
     gene            complement(3979..5313)
                     /locus_tag="JJL50_RS15545"
                     /old_locus_tag="JJL50_15545"
     CDS             complement(3979..5313)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014038012.1"
                     /locus_tag="JJL50_RS15545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15545"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_046988032.1"
                     /transl_table=11
                     /translation="MKLVSAWLRIPFWQRVVGGFVLGALAGWALGPAAETWFGPLGELY
                     VTLIKMIAVPLVFFAVINAISSLHGQKSVAALSGRTFLWFVITAALAVCVGLGVGTVLQ
                     PGAGGLQLSMASNYVPREVPSVVQVLLDVVPANVFYALSGIGTKVNAAGETVLAAGRGS
                     ILPVIFFAGLVGFAIVKLGEKVTEARKLVGQMSDIMIQVTRFVLEVTPIGTFGLIAGLV
                     GSYGFEKLLPLGHFVLALYVACALHIVVVYSALLLAHGLNPLKFFRGAAPGMQVAFVSS
                     SSFAAMPVALRSITHNLGVNKDYGSFAVPLGASIKMDGCGAIYPALCAVFIAQYSGVPL
                     TPEQYVVVLIASVLGSFGTAGVPGTAVIMATVVLSAANLPLETIGYLYAIDRILDMMRT
                     MTNVTGQMLVPVIVAKETGLLDQAVYDNPSSNVGVDDPDPTPPRG"
     gene            5468..7174
                     /locus_tag="JJL50_RS15550"
                     /old_locus_tag="JJL50_15550"
     CDS             5468..7174
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660635.1"
                     /locus_tag="JJL50_RS15550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15550"
                     /product="alkaline phosphatase"
                     /protein_id="WP_201117013.1"
                     /transl_table=11
                     /translation="MRRSVSLLAACAPTLLLGACASTPPASAPAGLKVAVDPVAHPAGE
                     TPQWWYRSGAAQAAANGAMSGKAKNVILFLGDGMSLTTVAASRIYEGQQKGGSGEENLL
                     SWERFPATAFSKTYNTDSQTPDSAGTMTAITTGVKTHMGAIGVSAGSRTDCADSLSKGL
                     LTWLQLADSAGLATGVVSTARLTHATPAATYAHSPERNWENDTDLTEAAKAAGCKDIAQ
                     QLLSTSRYGRGPLVALGGGRGEFTTVEERDPEYDDKVGQRLDGRSLVQEWQQAHPQGAY
                     VWNSKQLAAAANAPAILGLFEPDHMRYEYERPQDPGGEPSLAELTAAAIKNLAKHQEGY
                     VLMIEGARIDHANHSGNAYRALTETVALSDAVRVANELTSADDTLIIVTADHSHTLNFV
                     GYPARGNPILGKVKDKGGEDGAGKLDYALDGTGQPYTTLSYANGPGHTGSSNQQPAGPK
                     RYPHNPSSFEPANGRPNLREVDTEHPDYMQEALVPMKSESHGGEDVGIWARGPGSKAIR
                     GTLEQNAIYHMIVQATPALRERLCQAGTCDDKGVPVQLPAPTAFERKAEAK"
     gene            7171..7716
                     /locus_tag="JJL50_RS15555"
                     /old_locus_tag="JJL50_15555"
     CDS             7171..7716
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660636.1"
                     /locus_tag="JJL50_RS15555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15555"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_201117015.1"
                     /transl_table=11
                     /translation="MIVRQTYPAPASGRFARSLVLLGVLVSANAAAQTSACKLLTDEHG
                     LWPLPNCEVVDHRPKISADTLKDLNYDDHGLAVVYADQGFHYVNRKGRSLPVLTWDNGP
                     ETPQEGLLRARVGNRVAYFDLKFRQVVPGTFDFGWPFQDGVAEVCNGCRRGTPDADGHT
                     PMEGGERFRIDRSGRRVK"
     gene            8428..9714
                     /gene="tilS"
                     /locus_tag="JJL50_RS15560"
                     /old_locus_tag="JJL50_15560"
     CDS             8428..9714
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tilS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418067.1"
                     /locus_tag="JJL50_RS15560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15560"
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="WP_201117023.1"
                     /transl_table=11
                     /translation="MTEFPALVPLDAPLLVGYSGGVDSTVLLHWLWRCAQASGTALRAV
                     HVHHGLQPDADDWVLHCQQQCDGRGIELAVHRVQVENGTGLGTEGAARLARRAAFAAEL
                     RDGETLALAQHQDDQAETFLLRALRASGVDGLAAMSTYSRLGEHPLWRPLLAVPRSALL
                     DYARQHALRWIEDPSNAEDHADRNFLRLQVLPLLRQRWPHVAAALAGSATHCRQTRELL
                     DEEDAELIAHLEVVPRVLSLQLLRQVSPGRAARVLRAWVAGHGAEPLPATVLQQALDEL
                     LPAGNDRQARVRWHDHAIQQWRDHAYLLPAQLPALPHDWQAEWDGRAPLALPDGGQLCL
                     QGAPAFERRLQVRARVGGERILLPGRPHSHALKDCLQREHLAPWRRAQLPLVFDGPQLL
                     AAADVVIAAPLQAWLQAHDAQLQWRPGGW"
     gene            9751..10011
                     /locus_tag="JJL50_RS15565"
                     /old_locus_tag="JJL50_15565"
     CDS             9751..10011
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410522.1"
                     /locus_tag="JJL50_RS15565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15565"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_005410522.1"
                     /transl_table=11
                     /translation="MAKKSPENASPVAQFEQSLESLEQLVEQMETGELSLEASLSAYER
                     GVGLYRQCQQALEQAELRVRLLSDPAQPEASEPFDPPSHDG"
     gene            10001..10879
                     /locus_tag="JJL50_RS15570"
                     /old_locus_tag="JJL50_15570"
     CDS             10001..10879
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264747.1"
                     /locus_tag="JJL50_RS15570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15570"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_201117025.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-66, bitscore:
                     221.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEVLFARWRDRIESQLDAALPSPAEAPQGLHQAMRYSVLGGGK
                     RMRPLLVYASGHLFGAQPENLDAAAMAVELIHAYSLVHDDLPAMDDDALRRGKPTTHIA
                     FDEATAILAGDALQTRAFGLLADAPLPATLRVACLQTLAHASGAAGMCGGQALDIDATG
                     QQQTLAALTRMHALKTGALIRAAVRMGALCGQAHEPQLAQLDSFADALGLAFQVRDDIL
                     DVEASSEQLGKTAGKDQAQDKSTFPALLGMDGAKAQLHELAARMQSILAGHGEEADALR
                     ALATLAVERDH"
     gene            complement(10972..11343)
                     /locus_tag="JJL50_RS15575"
                     /old_locus_tag="JJL50_15575"
     CDS             complement(10972..11343)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647933.1"
                     /locus_tag="JJL50_RS15575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15575"
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_014038018.1"
                     /transl_table=11
                     /translation="MSEFDNVPPPPATTEAPADQRTMALAAHLLGIFTWFIGPLIIWLI
                     NKDDASKAFVTDQAKEALNFQITITIAMLICIVLTIVIIGGILAPIVGILNLVFCIIAA
                     VKANNGEAYRYPFALRLVK"
     gene            complement(11431..12798)
                     /gene="pmbA"
                     /locus_tag="JJL50_RS15580"
                     /old_locus_tag="JJL50_15580"
     CDS             complement(11431..12798)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pmbA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019662101.1"
                     /locus_tag="JJL50_RS15580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15580"
                     /product="metalloprotease PmbA"
                     /protein_id="WP_201117027.1"
                     /transl_table=11
                     /translation="MNVIAPEVAVGDDSLARLERLADLSQQLLDRARALGASQAEVSCS
                     EDRGLEVNVRLGEVETVQSTRDRGIAVTVYFGQRKGSASTGDLNEASLAATVEQACAIA
                     RHTEDDPAAGLAEAALMATDFPDLDAWHPWALQADEAVDLALACENAGREADAQIRNSD
                     GASVSSMQSLSVYANSHGFFGRERGTHHSVGCALIAGQGDGMQRDGWYTSALAREDLED
                     VGLVGRRAAERTVARLQPRSMATGTMPVLFAPEVARSLVGHLLSAVSGGALYRQASFLL
                     DSVGQQLFPDWMQIEELPHLRRGLRSAAFDGDGVATRASALVRDGVLQRYVLGSYSARK
                     LGLQTTANAGGVHNLQLAANAGSLQDIARQMGDGLLVTELMGQGVNGVTGDYSRGAGGF
                     RVENGEIQYPVDGVTIAGNLREMFSSIEAVGSDVDPRSHVRTGSILLGRMTIAGND"
     misc_feature    12842..12851
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     misc_feature    12843..12856
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.54"
                     /tool="antismash"
     gene            12867..13454
                     /gene="yjgA"
                     /locus_tag="JJL50_RS15585"
                     /old_locus_tag="JJL50_15585"
     CDS             12867..13454
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yjgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019182614.1"
                     /locus_tag="JJL50_RS15585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15585"
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="WP_049398682.1"
                     /transl_table=11
                     /translation="MRGRDEETGEFHDKSRSQNRRDALDVLALGEKLVSLTPAQLARLP
                     IPEDLLPHIAECKRITAHIAHKRQLAFLAKHMRREEDATLDAIRDALDANSETGRREVA
                     MMHRAEDWRERLLAEGDKALAALLDDYPQADRQQLRTLVRNAQAEKARNKPPRAYREIF
                     QVLRALMLPAALGLKASAEDADPVDSDEADED"
     gene            complement(13496..14941)
                     /gene="tldD"
                     /locus_tag="JJL50_RS15590"
                     /old_locus_tag="JJL50_15590"
     CDS             complement(13496..14941)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007972594.1"
                     /locus_tag="JJL50_RS15590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15590"
                     /product="metalloprotease TldD"
                     /protein_id="WP_201117028.1"
                     /transl_table=11
                     /translation="MTDIALTLAQDRLLRPGGLDTAGLERTFGQLLGPGVDFGDLYFQH
                     ARRESWSVEDGIVKDGAHSIEQGVGVRAISGEKTGFAYSDDIHADALLTAAQSARAISR
                     EGGAQSGRSLLRGNARALYPALDPIDGIGNEAKVEVLKRLDGYLRAADPRVKQVMVSLS
                     GGVDTVLIARSDGVLGADVRPLVRLNVQVIVEHNGRRESGYAGGGGRYGYEELFADGRP
                     EAFAREALRQALLNLDAVPAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYA
                     GRIGERVAAPGVTIVDDGTLDGRRGSLNIDDEGHPSQCTTLIEDGILVGYMQDSLNARL
                     MGMAPTGNGRRESFAHLTMPRMTNTYMRAGQHDPQEMIRSVKKGLYAVNFGGGQVDITS
                     GKYVFSATEAYLIEDGRITAPVKGATLIGNGPETMQKVRMVGNDLALDEGVGICGKDGQ
                     SVPVGVGQPSLLIEGITVGGTQA"
     misc_feature    14937..14951
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    14944..14958
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     gene            complement(15002..18856)
                     /locus_tag="JJL50_RS15595"
                     /old_locus_tag="JJL50_15595"
     CDS             complement(15002..18856)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647937.1"
                     /locus_tag="JJL50_RS15595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15595"
                     /product="YhdP family protein"
                     /protein_id="WP_201117029.1"
                     /transl_table=11
                     /translation="MSAPPRLRLRRIRRHFIAACAVGLVGLALLVGTFSQLLPLAERHP
                     DRIAAWLSERAGQPVRFDQLQTAWTRRGPLLQLKGLRIGAGQGLAIGEAEVLVSMYSGL
                     LPGRSLTELRLRGLALDLQQGEDGRWSVRGLPQAANGGDPLDALRRLGELQVIGGRLGV
                     HAPGLGIDTTLPRIDVRLRVNGDRLRVGVRAWAQTEALPLTAVLDVDRVRGNGQAWLGA
                     DPVDFHAWSPLLAAGGVRLREGKGELNLWLTLRDFAPVAVTTDSDLRDVRIDGAPMPSM
                     AAPQLQLQRLQARLRWQRQADGWALQVPRLRLKTEEGEQQLDGLQLQLGKQLRVRSGEV
                     QAGTALRALALSDRLEPALRRWLFLSRPQLDVRELQLAGDRDGPLWAQGELQSLGFASV
                     GNSPGLRGLGGRFEGDADGFSLQLQPQRQLQFDWPTGFGVRHDLHLAGQVVGWRDEGGG
                     WRIGTAAMRVEGTDYAADVRGGVWFQGDGTRPWLQLAAKLDDVPMTAAKRFWIHSKMSK
                     GATDWLDMALAGGQVRNGIGLVSGDLDDWPFDNNDGRFEATGHITNGDIRFQHDWPLMS
                     QVDADIAFIGPGFDMHGRGDLAGVAVQKFEAGIPDFGQQPLNVRADAQSEAGKLLAMLR
                     QSPLHKDYGDTLDNLTAAGPAHVTFDLLQPLHHDEGGGHLQGTVDLAGVKLVDKRFQLA
                     FDNMQGQARYSNGGFDAEALSVRHLGQDGRLSLRAGGYVHDSRLAFESQLSATLDAGVL
                     IDRAPEMAWLKPYITGTSPWTIAVSLPKVTPGAPAPPSELRLSSDLVGTRLDLPAPLDK
                     PAAEPLATTVAAQLPMGAGRIDVAFGQRLALAARSHNNQTGVQVTLGSDHVDREPPPSG
                     LTVNGRSPTLDALEWISLARGGSDDDAMPLRAVDVQVGQLKLIGGVFEQTRLQLRPGAQ
                     ALDVRLDGPSLAGRLTVPNADGGTISGQLDRVHWQSLPAAPGAPAAPARVQAGANDMDP
                     AKLPPFALDIADLKFGKVMLGQAVLRTRPLANGLNVDELRFRAPDQEIDISGRWLGRTG
                     GARTELTAQVRSEDLGGLMQNLDYGGQLRGGSGQAQLQATWSGGPSDFQLGNLQGRLDL
                     HARNGQLLELEPGAGRVLGLLSVTQLPRRLMFDFRDFFSKGFAFNQIDGSMQFGQGMAR
                     TDKVLIEGPAANITIRGQADLRNQQFDQTIDVNPRAGNLLTVVGAVAGGPVGAALGAAT
                     NAVLSKPLGEIGARTYKVTGPWKEPKVEVIERSRDKAPPPVPAPAPAIPPTVTGLPRSR
                     "
     gene            complement(18887..20374)
                     /gene="rng"
                     /locus_tag="JJL50_RS15600"
                     /old_locus_tag="JJL50_15600"
     CDS             complement(18887..20374)
                     /EC_number="3.1.26.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rng"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002802933.1"
                     /locus_tag="JJL50_RS15600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_15600"
                     /product="ribonuclease G"
                     /protein_id="WP_010482960.1"
                     /transl_table=11
                     /translation="MSEEILVNVTPRETRVAVIENGMLQELHIERGWRRGVVGNIYKGK
                     VQRVMPGMQAAFVEVGLERAAFLHANDVVRPAPVASADTENTTLPPPSSVPIVELLRDG
                     QDIVVQVVKDPIGTKGARLTTQISIPSRYMVLLPQSKVVGVSARIEDETERARLKALVT
                     ELSAQHGGYGYIVRTNAEGQPAEAIAEDIAYLSRVWNVVERRGREAASCSNIYEDLSLP
                     LRSVRDLIRKDVDKVKVDSKETFAQLQAFVAKYMPVLAEKIELYSGDRPIFDMFGVEDE
                     IGRALDKQVPLKSGGYLVIDQTEAMTTIDVNTGSFLGQRNLEETVFRTNLEAAQAVARQ
                     LRLRNLGGIIIIDFIDMDDAEHRRQVLRTLEKALARDHAKTTVYDFSPLGLVEMTRKRT
                     VESLERQLSETCPQCSGRGSIKTTETVTYEIFREITRAVRQFDAARLLVIASTKVVARI
                     TDEESAAVAELEEFLGKSIRFQADEQYLQEQFDVVLL"
ORIGIN
        1 cgtgcccgcg tggcgtgcag ccagtcacgt gcgttgcagc gcgcgccgaa ctgcagcagc
       61 cagcgccaca atgcagggtc caggcgcgta cgtacgtaca acggtgcacg cggatcgagc
      121 atccagcgca gcgcgcgcaa cggtacgcca ggcgctggca gcggcggcgc gtggctgggg
      181 gtgatggtgc cgcagttgcc atgcgaggtc gcgccgccga cacggccacg gtcgatcacg
      241 cgcacctgcc gcccctgtgc gcgcagcgcc agcgcagcgg ccagcccaat ggcaccggcg
      301 ccgaccacga tcacatcctc gcgcgcgccc tgcatcgatc agccctgccc ggccccgcgc
      361 cgcatcggcg gccactgccg gtaggtcatc gcacgccaca gccattccat cggcccgaaa
      421 cggaagcggc gcaaccacgc gtgcgaaatg cccacctgca cagcgaacag cagtagtgcg
      481 aacagcagct gcacgctgcg cggcatcacc tcgaaccatc ccagtccgta gtgatagaaa
      541 agcagcgtgc agaccagcga ctgcgccagg taatgggtca gcgccatgcg ccccaccggc
      601 gccagccagg ccaatcgcat gcgccagtgc acgatccacg ccaggtagcc caggcacatc
      661 ggcagcccgc caaccgtgac catggccatc gccgccgtca ccggcaggtt gtacgcaccg
      721 ggtgccaggt agggtttcca ggcaaccccc agcagcgtga ccagcaggcc cagcggcagt
      781 gcgatccagc gcagcgacgc gtacaggcgc gggaagcgct ccggcgtcgc cagcgcgcca
      841 ctgccggcga accagctgcc gatcaggaac atgcccagca cttccgggcc ggtgatcagc
      901 agcgccccca tggacgtacc gaactcactc aggcgctgca cattggcctg cgcccagctg
      961 ccctgcccgt acacctgccg ttgcagctcg atgctccgct gcgcctcagc aagcatgccc
     1021 tgcacatctt cggccgaagc catcgacacc atcgcgccga ccagcagcat catcgccaca
     1081 ccgccgaggt agaccatcaa ccccatccac ggcagccagc tgcgtggcgc ctcgcggcag
     1141 gccagcagcg gcaacgagat cagtgcatac atcaccagaa tgtcgccgga ccagaccagc
     1201 agtgcatggc acagaccgat cagcagcaag ccagcgctgc ggcgcaggta gaacggggtg
     1261 aagtcgcgcc cggcggcctc agcgcgctgc gccatcaccg cgaagccggc accgaacagc
     1321 aacgagaaca gggtgaagaa cttgccctgc acgaacacgt agacaaaggc atcggcccag
     1381 tagtcgatgc cctgccaatg cacgtcgatg ccggtgaacg ccaggtccag cggcccgctg
     1441 aaggcctcga tgttcatcag caggatgccc agcagcgcag caccgcgcag cacgtcaagc
     1501 acggcgatgc gttcgccgga agccaccggc tgcagggaag gagaagcggc gttcacaggg
     1561 cgtccgtcgg gcaggtccac cattatgccg ccggcctgcg cgccatggat ggccgcgccg
     1621 tgttccacaa acgcaacggc ccgccgaagc gggccgttgc tgccatcacg atcgcgctgc
     1681 gatcagtgct ggtgaccgcc gtcgccgtgg acgtggccgt ggtcgatttc ttccttgccg
     1741 gcttcgcgca catcgacgat ttccacgtcg aagtgcaggt ccttgccggc catcggatgg
     1801 ttcaggtcga cgtcgacgac gctcatgccg accttctgca cggtcaccgc acgcgggccg
     1861 aagttggtct gcagcacaac ctgctggccc ggagccagct tggtgttgcc gaagtgcttc
     1921 ttcggcacgc gctgggacag gccctcacga cgctcgccgt aggcatcggc agcgttgacg
     1981 tcgacgctga aggtcgcgcc ggcttccttg tccatcatgg cgttttccag gcccggaatg
     2041 atgttgccgt ggccgatcag gatcgccagc ggctcgccgc ggtccttgga cgattcgatc
     2101 ggctcctggc cgacttcgga aacggtgtag tggaagcgga caacgcggtc tttttcgatc
     2161 ttcatgcgca actctgtctg gatctgccgg aggcaggcgg gttggggcgg gttgtcgccc
     2221 ggcggggacg ccgccatcat gacggccaat cctaaggtgg cgcattatcc ggagatcatg
     2281 cacatcacgc cagtttcgtc cggcctgcgc cggctcctcg ccccggccct gctgctggcc
     2341 ctgcccgtgc tgatgaccgc ctgcggcggc ggcaaggcca cccgacccgc gccgcccccg
     2401 ccgaccgcga actggccgaa gaccgtgccg gacaatcccg aggcggccaa ctcggtgctg
     2461 atgcgcgcca tcagcctggt cggcaccccc tatcgctatg gcggcaatac ccccgactcc
     2521 ggcttcgact gcagcggcct ggtggcctac gtctaccgcg agatgctgga cctgaaactg
     2581 ccgcgcacct cgcgcgacct ggcggcggta cagggcccga agatcgaccc gcagcgcctg
     2641 gccaccggcg acctggtgtt cttcggcagc cgcggcagcg tcacccatgt cggcatttat
     2701 gtgggtgaag ggcgcttcgt gcacgcgccg agcaccggtg gcacggtccg gctggactcg
     2761 ctcagcggtc cgtactggaa ggaccactac accggggcga aacgcgtcct tcgctaagat
     2821 gaacaggcga tatgttcaaa attgtgacgc acatcaccgt gcaactaacg atttactaac
     2881 ggaattttta acttattgcc gcttttacag ggcatgatgc cccatcgttt ttttcctgtg
     2941 accgacgcgt gacgactgac gacctgaaaa gcgaaggcca gacttccgta tcttcacgta
     3001 gtgcccgccc gctgttgctt ggcctggcac tgtgtctgac cagccttccg gcctggtcgc
     3061 agactgctcc gaaccgttcc gatgtgaccc cggccccggt ggccgagagc accgcccgac
     3121 cggccgccaa ggccgaggct gccgctccgc agcgcagccg cgtcgatgcc gccgccagtg
     3181 ccacgctggc cgccctgctg ccgcacctgg ccgccaatga caccattccg ctgatggacc
     3241 gctcggccgt ggtggccggc gacctcagcc gcctgctcgc caactacgac accagcagcg
     3301 ccgccaatgg cagcgttgtc ggtaccgccg ccgacaacgg caaggtgcag tcgctgctgc
     3361 gccgcgcgat gaccctgctg ggcaccccgt accgatgggg tggcagcaac ccggacagcg
     3421 gtttcgactg cagcggcctg gtcggttacg tgttccgctc ggccttgggc atcgagctgc
     3481 cgcgcgtgtc gcgcgagatg gcacacgacg acaacgccga actgatcaat gatcgcaccg
     3541 cactggctgc cggtgacctg gtgttcttcg gccgcaaggg ccgcgtcgac cacgtcggca
     3601 tctatgttgg cgatggccgc ttcctgcacg caccgagctc cggcaaggac gtccgcgtgg
     3661 acaccctgct cagcggctac tggggcaaca agttcatgca ggcccgccgg gtcgatctct
     3721 gacccgctgg cgccactgcg ccgcctgaca cgagaaagcc gctgccctgc agcggctttt
     3781 ttgtttgcgc ccccactggg tgccgacctt ggccggcact gcgccacctg ccccagtggg
     3841 tgccgaccgt tggtcggcac tgcggccatc cacgcatggc gtggatctac cggggaccta
     3901 ccctgatcgg caccgcgcca gtcagctcca aaacaaaaag cccgccgttc agggcgggcc
     3961 tttcatctcc acgcaacctc agccgcgtgg cggtgtcggg tccggatcgt ccacgcccac
     4021 gttgctggac gggttgtcat acaccgcctg gtcaagcagg ccggtttcct tggccacgat
     4081 caccggcacc agcatctggc ccgtcacatt cgtcatcgtg cgcatcatgt ccaggatgcg
     4141 gtcgatggca tacaggtagc cgatggtctc cagcggcagg ttggctgcgc tcagcaccac
     4201 cgtggccatg atcaccgcag tacccggcac gccggccgta ccgaagctgc ccagcaccga
     4261 ggcaatcagc accaccacgt actgctccgg ggtcagcggc acaccgctgt actgcgcgat
     4321 gaacaccgcg cacaacgccg ggtagatcgc gccgcagcca tccatcttga tgctggcacc
     4381 cagcggcacc gcgaacgaac cgtagtcctt gttcacgccc aggttgtggg tgatcgaacg
     4441 cagcgccacc ggcatcgcgg cgaagctgga cgagctgacg aaggcaacct gcatgcccgg
     4501 cgccgcgcca cggaagaact tcagcgggtt caggccgtgt gccagcagca gtgcgctgta
     4561 gaccaccacg atgtgcaggg cgcaggccac gtacagcgcc agcacgaaat gccccagcgg
     4621 cagcagcttc tcgaagccgt agctgccgac caggccagca atcaggccga aggtcccgat
     4681 cggggtgact tccagcacga agcgggtcac ctggatcatg atgtcgctca tctgcccgac
     4741 cagcttgcgc gcctcggtca ccttctcgcc cagcttgacg atggcaaagc ccaccaggcc
     4801 agcgaagaag atcactggca ggatcgagcc gcgaccggca gccagcacgg tctcaccggc
     4861 cgcattgacc ttggtgccga tgccggacag cgcgtagaag acattggccg gcaccacgtc
     4921 cagcagcacc tgcaccacgc tgggcacttc gcgcggcacg tagttgctgg ccatcgacag
     4981 ctgcaggcca ccggcgccgg gctgcagcac ggtacccacg cccaggccga cgcacaccgc
     5041 caacgcggcg gtgatcacga accacaggaa ggtgcggcca ctgagcgcgg cgaccgactt
     5101 ctggccgtgc agcgacgaga ttgcgttgat gaccgcgaag aacaccagcg gcacggcgat
     5161 catcttgatc agggtgacgt acagctcgcc gagcgggccg aaccacgttt ccgcggccgg
     5221 gccgagcgcc cagccggcca gcgcgccgag cacgaagcca ccgaccacgc gctgccagaa
     5281 tggaatccgc agccaggcag agaccagctt cataggcaat ccagagggga aggaagggat
     5341 gctggcacga tagcccaagg tggcccgcag aacgaccgcc cggccggcaa atcagtgtgt
     5401 catcggcgtg ccttgcgagg gcgggcataa tgaacgtccc gttacagttt gtgagatccc
     5461 agcgtccatg cgccgttccg tctccctgtt ggccgcctgc gcccccaccc tgctgctggg
     5521 cgcctgcgcc agcacccccc ccgcgtccgc cccggccggc ctgaaggtcg ccgtcgaccc
     5581 cgttgcccat ccggccggcg agaccccgca gtggtggtac cgcagcggcg ccgcccaggc
     5641 cgccgccaac ggcgcgatgt ccggcaaggc caagaacgtc atcctgttcc tcggcgacgg
     5701 catgagcctg accacggtgg ccgcctcgcg catctacgaa ggccagcaga agggcggctc
     5761 gggtgaagag aacctgctgt cctgggagcg cttcccggcc acggccttca gcaagaccta
     5821 caacaccgat tcgcagaccc cggattcggc cggcaccatg accgccatca ccaccggcgt
     5881 gaagacccac atgggcgcga tcggcgtcag cgccggcagc cgcaccgact gcgccgacag
     5941 cctgtccaag ggcctgctga cctggctgca gctggccgac agcgccggcc tggccaccgg
     6001 tgtggtgtcc accgcacgcc tgacccatgc cactccggcc gccacctacg cgcactcgcc
     6061 cgagcgcaac tgggaaaacg acaccgacct gaccgaagcc gcgaaggccg ccggctgcaa
     6121 ggacatcgcc cagcagctgt tgtccacctc gcgctatggc cgtggcccgc tggtcgccct
     6181 cggcggtggt cgtggtgagt tcaccaccgt ggaagagcgc gatcccgagt acgacgacaa
     6241 ggtcggccag cgcctggacg gccgcagcct ggtgcaggaa tggcagcagg cgcatccgca
     6301 gggtgcctac gtgtggaaca gcaagcagct ggccgccgcc gcgaatgcgc cggccatcct
     6361 tggcctgttc gagccggacc acatgcgcta cgagtacgag cgcccgcagg atccgggcgg
     6421 tgagccgagc ctggccgaac tgactgccgc cgcgatcaag aatctggcca agcaccagga
     6481 aggctacgta ctgatgatcg aaggcgcgcg catcgaccac gccaaccaca gcggcaacgc
     6541 ctaccgtgcg ctgaccgaga ccgtggccct gtccgacgcg gtgcgcgtgg ccaacgaact
     6601 gacctcggcc gacgataccc tgatcatcgt caccgccgac cactcgcaca ccctgaactt
     6661 cgtcggctac ccggcacgcg gcaacccgat cctgggcaag gtgaaggaca agggcggcga
     6721 agacggcgcc ggcaagctcg actacgcgct ggacggcacc ggccagccgt acaccaccct
     6781 gagctacgcc aatggcccgg gccataccgg cagcagcaac cagcagccgg ccggtccgaa
     6841 gcgttacccg cataacccga gcagcttcga accggccaac ggccgcccga acctgcgcga
     6901 ggtcgacacc gagcatccgg actacatgca ggaagcactg gtgccgatga agtccgagtc
     6961 gcacggcggc gaagacgtcg gtatctgggc acgcggcccg ggcagcaagg cgatccgcgg
     7021 cacactggaa cagaacgcga tctaccacat gatcgtgcag gccaccccgg ccctgcgcga
     7081 acgcctgtgc caggccggca cctgcgatga caagggcgtg ccggtgcagc tgccggcgcc
     7141 gaccgcattc gagcgcaagg ccgaggccaa gtgatcgtga ggcagaccta ccctgctcct
     7201 gccagcggcc gcttcgcgcg gtcgctggtc ctgcttggcg tgctggtcag tgccaatgca
     7261 gcggcacaga catcggcgtg caagctgctg accgacgaac acgggttgtg gccgctgccc
     7321 aactgcgaag tggtcgatca ccggccgaag atcagtgccg acacattgaa ggacctgaat
     7381 tacgacgacc atggcctggc cgtggtgtac gccgaccagg gcttccacta cgtcaaccgc
     7441 aagggccgca gcctgccggt actgacctgg gacaacggtc cggaaacacc gcaggaaggc
     7501 ctgctgcgcg cccgcgtcgg caaccgcgtg gcctacttcg atctgaagtt ccgccaggtg
     7561 gtgcccggca ccttcgattt cggttggccg ttccaggatg gcgtggccga agtctgcaat
     7621 ggctgccggc gcggcacgcc ggatgccgat ggccacacgc cgatggaagg cggagagcgg
     7681 ttccgcatcg accgttcggg ccgtcgggtg aagtagggtt ttcggcaggg ctgcgccctg
     7741 cacctgcaga cgcaacggca acggccgaag caacagcgtg cattccgtgg gatggcgggt
     7801 cactgtgggt ttgcggggac ggcgcaagta cgtccatgta gccttgatcg ccgcatccat
     7861 gcggctcaca ccccgcaaac ccacaccgcc ccacctctga cagatctccg cggctgttgg
     7921 taggtgtcga ccttggccga cacatctgtc agatatcgaa tgagtcatcc acgcatggcg
     7981 tggatctact gtgtcgacca aggtcgacac ctaccaaagc ggtgcacgac gccgttctgg
     8041 cagatcgcgg cattctgtcg aagccggggt gggtccggtt gcgggggcgt gagccgcatg
     8101 ggcccgaggc atgcctcggg cgggttgggc aggacgcccg accccggtct tgccgtgtgc
     8161 gcaggactgc gcacacgagc aagcggcgac cgagcttaca tgggtgaggg cgctttgctt
     8221 gcgaagcact gcttcgcaag cgcccgaacg cacagccgcc agcggctggg ccgggccccg
     8281 gagggggact tgcagcggcc cccgcaaccg ggcccacccc gccaaccctc aggaaacccg
     8341 cttctgctgt tgcttcggcc gttgccgttg cttgcgcgtc tgcgggtgca gggcgcagcc
     8401 ctgccgacca accctatact tgccgccgtg actgaatttc ctgccctcgt tccgctggat
     8461 gcgccgctgc tggtgggcta cagcggtggt gtcgactcca ccgtgctgct gcattggctg
     8521 tggcgctgcg cgcaagcttc cggcacggcg ctgcgcgcgg tgcacgtgca ccacgggctg
     8581 cagcccgatg cggatgactg ggtgctgcac tgccagcagc aatgcgacgg caggggcatc
     8641 gaactggccg tgcaccgcgt gcaggtcgag aacggcacag gcctgggcac cgagggtgcc
     8701 gcgcgactgg cacgacgcgc cgcgttcgcg gccgaactgc gcgacggcga aaccctggcg
     8761 ctggcacagc accaggacga ccaggccgag accttcctgt tgcgcgccct gcgcgcttcc
     8821 ggcgtcgatg gccttgcagc catgtccaca tacagccgtc ttggcgaaca tcccttgtgg
     8881 cgcccgctgc tcgcggtacc acgcagtgca ctgctcgact acgcgcgcca gcacgcgctg
     8941 cgctggatcg aagaccccag caacgcggaa gaccacgccg atcgcaactt cctgcgcctg
     9001 caggtgttgc cgttgctgcg ccagcgctgg ccgcatgtgg ctgcagcatt ggcgggcagc
     9061 gcgacgcatt gccggcagac ccgcgaactg ctggacgagg aagacgccga gctgatcgcg
     9121 catctggagg tcgtaccgcg ggtgctgtcg ctgcagctgc tgcgccaggt atcaccgggc
     9181 cgtgcggcac gcgtgctgcg cgcctgggtg gccggccacg gtgcggagcc gctgccggcc
     9241 acggtgctgc agcaggcact ggacgagctg ctgccggccg gcaacgatcg ccaggcgcgg
     9301 gtacgctggc acgatcatgc catccagcaa tggcgcgatc atgcctatct cctgcccgcg
     9361 cagctgccgg cgcttcccca tgattggcag gccgaatggg atggacgcgc gccattggcg
     9421 ttgcccgatg gcggtcaact gtgcctgcag ggcgccccgg ccttcgagcg ccgattgcag
     9481 gtccgtgcac gcgtgggcgg ggagcgcatc ctgctgcccg gtcgcccgca ttcgcatgcg
     9541 ctgaaggact gcctgcaacg cgaacacctt gccccctggc gacgcgccca actgccgctg
     9601 gtcttcgatg gaccacagct gcttgccgcc gccgacgtgg tcattgcggc tcccctgcag
     9661 gcctggttgc aggcccatga cgcgcagctg cagtggcgtc ccggcggctg gtgaattgac
     9721 ccccgcccgc ggcccgtcca cacttgccac atggccaaga agtcccccga aaacgcctcc
     9781 cctgtcgccc agttcgagca gtcgctcgaa tcgctggagc agttggtgga gcagatggaa
     9841 accggcgagc tgagcctgga agcctcgctc agtgcttacg aacgtggcgt cggtctgtac
     9901 cgccagtgcc agcaggcgct ggagcaggcc gaactgcgcg tgcgcctgct cagcgatccg
     9961 gcgcagccgg aagcctccga gcctttcgat ccgcccagcc atgacggctg aggttctgtt
    10021 cgcgcgctgg cgcgaccgta tcgaaagcca gctcgacgct gccctgccct cgcctgccga
    10081 agcaccgcag ggcctgcacc aggccatgcg ctattccgtg ctgggcggtg gcaagcgcat
    10141 gcgtccgctg ctggtgtatg ccagtggcca cctgttcggc gcacagcctg aaaacctgga
    10201 tgcggcggcg atggccgtcg agctcatcca cgcctattcg ctggtgcatg acgacctgcc
    10261 ggcgatggac gatgacgccc tgcgacgcgg caagccgacc acccacatcg ccttcgacga
    10321 agccaccgcg atcctggccg gcgacgccct gcagacgcgt gccttcggcc tgctggccga
    10381 tgcaccgctg ccggccacgc tgcgcgtggc ctgcctgcag accctggccc acgcttccgg
    10441 cgccgctggc atgtgcggtg gccaggcgct ggatatcgat gccaccggcc agcagcagac
    10501 gctggcggca ttgacccgca tgcatgccct gaagaccggc gcgctgatcc gtgcggcggt
    10561 gcgcatgggc gcgctgtgcg gccaggccca cgaaccgcag ctggcccagc tcgacagctt
    10621 cgccgatgca ctcggcctgg cgttccaggt gcgtgacgac atcctcgatg tcgaggccag
    10681 ttccgaacag ctgggcaaga ctgccggcaa ggaccaggca caggacaaga gcaccttccc
    10741 cgccctgctt ggcatggacg gtgcgaaggc ccagctgcac gaactcgccg cacgcatgca
    10801 gtcgatcctg gccggccatg gcgaggaagc cgatgcgttg cgcgcgctgg cgacgctggc
    10861 ggtcgaacgc gatcattgag tgctgcgcgc tcgccgggta ccgcccgtca ctctccgcac
    10921 atgaaaacgc ccggcaatgc cgggcgtttt cagttccgca tgtggccgat cttacttgac
    10981 caggcgcagc gcgaacgggt agcggtaggc ttcgccgttg ttcgccttga ccgcggcgat
    11041 gatgcagaac accaagttca ggatgccgac gatcggggcc aggatgccac cgatgatcac
    11101 gatggtcagc acgatgcaga tcagcatcgc gatggtgatg gtgatctgga agttcagcgc
    11161 ttccttggcc tggtcggtca cgaaggcctt gctggcgtca tccttgttga tcagccagat
    11221 gatcagcggg ccgatgaacc aggtgaaaat gcccagcagg tgcgcagcca gcgccatggt
    11281 gcgctggtcg gccggggcct cggtggtggc cggcggcggc gggacgttat cgaattcgct
    11341 cacgacaaaa ctccttttca ttgggtggtc ttgacccacc agcaccaagc tggttgcgtc
    11401 aggcgggcat agcttacgcc atcaatacca tcaatcatta ccggcgatgg tcatccgccc
    11461 cagcaggatc gaaccggtcc ggacgtgcga gcgcgggtcg acgtcgctgc cgaccgcttc
    11521 gatgctgctg aacatctcgc gcaggttgcc ggcgatggtg acgccatcca ccgggtactg
    11581 gatctcacca ttctcgacgc ggaagccgcc ggcaccgcgc gagtagtcgc cggtcacccc
    11641 gttcacgccc tgccccatca gttcggtcac cagcaggcca tcgcccatct gccgggcgat
    11701 gtcctgcagg gaacccgcgt tggcggccag ctgcaggttg tgcacgccac cggcattggc
    11761 ggtggtctgc aggcccagct tgcgtgccga gtagctgccc agcacatagc gctgcagcac
    11821 gccgtcacgg accagggccg aagcacgcgt ggccacgccg tcaccgtcga aggcggccga
    11881 gcgcaggcca cggcgcaggt ggggcagttc ctcgatctgc atccagtccg ggaacagctg
    11941 ctggccaacg ctgtccagca ggaagctggc ctggcggtac agcgcaccgc cggacaccgc
    12001 cgacagcagg tggccaacca ggctgcgcgc tacttccggg gcgaacagca ccggcatggt
    12061 gccggtggcc atcgagcgag gctgcaggcg ggcgacggta cgctcggcag cacgacggcc
    12121 gaccaggccc acgtcttcca ggtcctcccg ggccaacgcg ctggtgtacc agccatcgcg
    12181 ctgcatgcca tcgccctggc cggcgatcag cgcacagccc accgaatgat gggtgccacg
    12241 ctcacggccg aaaaagccat gcgaattggc gtacaccgac aggctctgca tgctcgacac
    12301 cgaggcgccg tcggaattac ggatctgcgc atcggcctca cggcctgcgt tctcgcaggc
    12361 cagggccagg tccaccgcct cgtcggcctg cagcgcccag gggtgccagg catccagatc
    12421 cgggaaatcg gtggccatca acgcggcctc ggccaagccg gcagccgggt catcttcggt
    12481 gtgccgggcg atcgcacagg cctgctcgac cgtggcggca aggctggcct cgttcaggtc
    12541 gccggtgctg gcgctgccct tgcgttggcc gaaatagacg gtgacggcga taccgcggtc
    12601 acgggtggac tgcacggtct ccacctcgcc aaggcggaca ttgacctcca ggccacgatc
    12661 ctcgctgcag ctgacctcgg cctggctggc gcccagcgca cgggcgcggt cgagcagctg
    12721 ctgggagagg tcggccagcc gttccagccg ggccaggctg tcgtcgccga cagcgacttc
    12781 aggggcgatc acgttcaatg ctttatcctg tacgggttgg gcccggcatc acgccgggcg
    12841 actttttttg agatcaggta ggaacgatgc gcggacgcga cgaagaaacc ggtgaattcc
    12901 acgacaagag ccgcagccag aaccggcgcg acgcgctcga cgtcctggcc ctgggcgaga
    12961 agctggtgtc gttgaccccg gcgcagctgg cacgcctgcc gatcccggaa gacctgctgc
    13021 cgcatatcgc cgagtgcaag cgcatcaccg cccacatcgc ccacaagcgc cagctggcgt
    13081 tcctggccaa gcacatgcgc cgcgaagaag acgccacgct ggatgcgatc cgcgatgcgc
    13141 tggacgccaa cagcgaaacc ggccgccgcg aagtggcgat gatgcaccgc gcggaagact
    13201 ggcgcgagcg cctgctggcc gagggtgaca aggcgctggc tgcactgctg gacgactacc
    13261 cgcaggccga ccgccagcag ctgcgcacgc tggtgcgcaa tgcccaggcc gaaaaggcca
    13321 ggaacaagcc gccacgcgcc taccgcgaaa tcttccaggt gctgcgcgcc ctgatgctgc
    13381 cggccgcact gggcctgaag gccagcgccg aagacgccga ccccgtcgac agcgacgaag
    13441 ccgacgagga ctgagtccgc gccggcctgg gcggtggcac tggccatcgc ccggctcagg
    13501 cctgggtacc gccgacggtg atgccctcga tcagcagcga gggctggccg acacccacgg
    13561 gcacgctctg cccgtccttg ccacagatgc ccacgccctc gtccagggcc agatcgttgc
    13621 cgaccatgcg caccttctgc atggtttccg gaccattgcc gatcagcgtc gcacccttca
    13681 ccggcgcggt gatgcggcca tcctcgatca ggtaggcctc agtggccgag aacacgtact
    13741 tgccgctggt gatgtcgacc tggccgccac cgaagttgac tgcgtacagg cccttcttca
    13801 ccgaacggat catttcctgc gggtcatgct ggccggcgcg catgtaggtg ttggtcatgc
    13861 gcggcatggt caggtgcgcg aacgattcgc ggcggccgtt gccggtcggc gccatgccca
    13921 tcagccgcgc attgaggctg tcctgcatgt atcccaccag aatgccgtcc tcgatcaagg
    13981 tggtgcactg gctcggatgg ccctcgtcgt cgatgttcaa cgaaccacgg cgtccgtcca
    14041 gcgtgccgtc atcgacgatg gtcacgcccg gggcggcaac gcgctcgccg atgcggcccg
    14101 cgtagacgct ggtgcccttg cggttgaagt cgccttccag gccatggccg accgcttcat
    14161 gcagcagcac gccgggccag cccggaccaa gcaccaccgg catcaccccg gccggtgccg
    14221 gaacggcgtc caggttcagc agcgcctggc gcagcgcctc gcgggcaaag gcctcggggc
    14281 gaccgtccgc gaacagctcc tcatacccgt agcggccacc accgccggca tagccggact
    14341 cgcggcggcc gttgtgctcg acgatcacct gcacgttcag gcgcaccagc gggcgcacgt
    14401 cagcgcccag cacaccgtcg ctgcgggcga taagtaccgt atcgacgccg ccggacaggc
    14461 tcaccatcac ctgcttcacg cgcgggtcgg cggcgcgcag gtagccatcc aggcgcttga
    14521 gcacctcgac cttggcctcg ttgccgatgc catcgatcgg gtccagcgcc gggtacagcg
    14581 cgcgcgcgtt gccgcgcagc agcgaccgcc cggactgggc gccaccttca cgcgagatcg
    14641 cacgcgccga ctgcgccgcc gtcagcagtg catcggcatg gatgtcgtcg gagtaggcga
    14701 agccggtctt ctcgccggaa atcgcccgca cgcccacgcc ttgctcgatg gaatgggcgc
    14761 cgtccttgac gatgccgtct tccacgctcc agctctcgcg gcgggcatgc tggaaataaa
    14821 ggtcgccgaa gtccacaccg gggccgagca gctggccgaa ggtgcgctcc aggccagcgg
    14881 tatccaggcc gccggggcgc agcaggcggt cttgggcaag cgtcagggcg atatcagtca
    14941 tggttctcga tctggggatg cgggggcgct caggcaagcc ccgtgaacag gaaagccgcg
    15001 ctcaacgcga gcgcggcagg ccggtgacgg tcggcggaat ggccggcgcc ggtgccggta
    15061 cgggtggcgg agccttgtcg cggctgcgct cgatcacttc caccttcggt tccttccatg
    15121 gaccggtcac cttgtaggta cgggcgccaa tctcgcccaa tggcttggac aataccgcat
    15181 tggtggccgc gcccagcgcc gcccccaccg ggccaccggc gaccgcaccc accacggtca
    15241 gcagattgcc tgcacgcggg ttgacgtcga tggtctggtc gaactgctgg ttgcgcaggt
    15301 cggcctggcc gcggatggtg atgttggctg ccgggccttc gatcagcact ttgtcggtgc
    15361 gtgccatgcc ctggccgaac tgcatgctgc cgtcgatctg gttgaacgcg aagcccttgg
    15421 agaagaagtc gcggaagtcg aacatcaggc gccgcggcag ctgggtgaca ctgagcaggc
    15481 ccagcacccg gccagcgccc ggttccagct ccagcagctg gccgttgcgc gcgtgcaggt
    15541 ccaggcggcc ctgcaggttg cccagctgga agtccgacgg ccccccactc cacgtggcct
    15601 gcagctgcgc ctggccggaa ccgccacgca gctggccgcc gtagtcgagg ttctgcatca
    15661 gtccgcccag gtcctcgctg cgcacctgtg cggtcagctc ggtgcgggca ccaccggtgc
    15721 ggcccagcca gcgaccgctg atgtcgatct cctggtcggg cgcacggaag cgcagctcgt
    15781 ccacgttcag gccattggcc agcggccgcg tacgcagtac cgcctggccc agcatcacct
    15841 tgccgaactt caggtcggcg atgtccagcg cgaacggcgg cagcttggcc gggtccatgt
    15901 cgttggcgcc ggcctgtacc cgtgccggtg cggccggtgc acccggagcc gccggcaggg
    15961 attgccagtg cacgcggtcg agctggccac tgatggtgcc gccgtctgca ttggggacgg
    16021 tcaggcgccc ggccagcgac gggccgtcca ggcgcacatc cagtgcctgc gcgcccgggc
    16081 gcagctgcaa ccgggtctgc tcgaacacgc caccgatcag cttcaactgg ccgacctgca
    16141 cgtccaccgc acgcagcggc atggcgtcgt catcactgcc accccgcgcc agactgatcc
    16201 actccagagc gtccagggtc ggactgcggc cattgacggt caatccgctc ggcggcggct
    16261 cgcggtcgac atggtcgctg cccagcgtca cctgcacacc ggtctggttg ttgtggctgc
    16321 gtgcggccag cgccaggcgc tggccgaacg caacgtcgat gcggccggcc cccatcggca
    16381 gctgtgcagc cacggtggtc gccaacggct cggcagccgg tttgtccagc ggcgccggca
    16441 ggtccagccg ggtcccgacc agatcggaac tcaaccgcag ctcgctgggc ggcgcaggcg
    16501 cccccggagt gaccttgggc aggctgaccg cgatggtcca cggcgaggtt ccggtgatgt
    16561 agggcttgag ccaggccatc tccggcgcgc ggtcgatcag cacgccagca tccagcgtgg
    16621 ccgacagctg cgattcgaag gccagtctgc tgtcgtgcac gtagccaccg gcacgcaggc
    16681 tcaggcgacc gtcctggccg aggtggcgca ccgacagtgc ctcggcatcg aaaccgccat
    16741 tgctgtagcg cgcctgcccc tgcatgttgt cgaaggcgag ctggaagcgc ttgtcgacca
    16801 gcttcacgcc ggccagatca accgtcccct gcaggtggcc gccaccttca tcgtggtgca
    16861 gtggctgcag cagatcgaag gtcacatgcg ccgggccggc agcagtgagg ttgtccaggg
    16921 tgtcgccata atccttgtgc agcgggctct gccgcagcat cgccagcagc ttgcccgcct
    16981 cgctctgcgc atcggcgcgc acattcagcg gctgctgccc gaaatccgga atgcccgcct
    17041 cgaacttctg caccgccaca ccggccagat cgccgcgccc atgcatgtcg aagccggggc
    17101 cgatgaaggc gatatcggcg tcgacctggc tcatcaacgg ccaatcgtgc tggaaacgga
    17161 tgtcaccgtt ggtgatatgg ccggtggcct cgaagcggcc atcgttgttg tcgaacggcc
    17221 agtcgtccag gtcgccactg accaggccga tgccattgcg cacctggccg ccggccagcg
    17281 ccatgtccag ccagtcggtg gcgcccttgc tcatcttgga gtggatccag aagcgcttgg
    17341 ccgcggtcat cggcacgtcg tccagcttgg ccgccagctg cagccacggc cgcgtaccgt
    17401 cgccctggaa ccagaccccg ccgcgcacgt cggccgcata gtcggtgcct tccacgcgca
    17461 tcgccgcagt accgatacgc caaccaccgc cctcgtcgcg ccagcccacc acctgtcccg
    17521 ccagatgcag gtcatgacgc acaccaaagc cggtcggcca atcgaactgc agctgccgtt
    17581 gcggctgcaa ctgcaggctg aagccatccg cgtcgccttc gaagcgcccg cccaggccgc
    17641 gcaggccggg cgaattgccc acgctggcga agcccagcga ctgcagttcg ccctgcgccc
    17701 acagcgggcc atcgcgatcg cccgccagct gcaactcgcg cacatccagc tgcggcctgg
    17761 acaggaacag ccagcgacgc agggccggtt cgagacgatc gctcagggcc agcgcacgca
    17821 gcgcggtgcc ggcctgcact tcgccagaac ggacccgcag ctgcttgcca agctgcagct
    17881 gcaggccatc gagctgctgc tcgccctctt cggttttcag gcgcaggcgc ggcacctgca
    17941 acgcccagcc atcagcctgg cgctgccagc gcaggcgtgc ctgcaaccgc tgcagctgca
    18001 gctgcggagc cgccatcgag ggcatcggtg cgccatcgat gcggacatca cgcaggtccg
    18061 aatcggtggt caccgccacc ggcgcgaaat cgcgcagggt cagccacagg ttgagttcgc
    18121 ccttgccttc gcgcaggcgc acaccgccgg ccgccagcag cggcgaccag gcatggaaat
    18181 cgactggatc ggcgcccagc caggcctggc cattgccgcg cacgcggtcc acgtccagca
    18241 ccgccgtcaa cggcagcgct tcggtctggg cccaggcacg cacgcctaca cgcaggcggt
    18301 cgccgttgac ccgcaggcgc acgtcgatgc gtggcagcgt ggtgtcgatc cccagccccg
    18361 gcgcatgcac gcccaggcgg cctccgatca cctgcagctc gcccagccgg cgcagcgcat
    18421 ccagcgggtc cccgccattg gcggcctgcg gcaggccgcg taccgaccag cgaccgtcct
    18481 cgccctgctg caggtcgagc gccaggccac gcaggcgcag ctcggtcagc gaccggccag
    18541 gcaacaggcc gctgtacatc gataccagca cctcggcctc gccgatcgcc aggccctggc
    18601 cggcgccgat gcgcaggccc ttgagctgca gcagcggacc acgccgggtc caggcggtct
    18661 gcagctggtc gaaacgcacc ggctggccag cacgctcgct cagccaggcg gcaatcctgt
    18721 cgggatggcg ctcagccagc ggcagcagct ggctgaaggt gcccaccagc agtgcaagcc
    18781 cgaccaggcc taccgcgcag gcggcaatga aatgacggcg gatccttcgc agtcgcaggc
    18841 gcggcggcgc gctcatcggc caccgccggc ctgcggccgg cgaggatcag agcagaacga
    18901 catcgaattg ctcctgcagg tactgctcgt ccgcctggaa gcggatgctc ttgccgagga
    18961 attcctccag ctcggccacc gccgcggatt cctcgtcggt gatgcgcgcg accaccttgg
    19021 tcgacgcgat caccagcagg cgcgcggcat cgaactggcg cacggcacgg gtgatctcgc
    19081 ggaagatctc gtaggtcacc gtctcggtgg tcttgatgct gccgcggccg ctgcactgcg
    19141 ggcaggtctc cgacagctgg cgctccaggc tttccaccgt gcgcttgcgg gtcatctcca
    19201 ccaggcccag cggcgagaag tcgtacaccg tggtcttggc atggtcgcgg gccagcgcct
    19261 tttccagggt gcgcagcacc tggcggcgat gctcggcatc gtccatgtcg atgaaatcga
    19321 tgatgatgat gccgcccagg ttgcgcagtc gcagctgccg tgccaccgcc tgtgccgctt
    19381 ccaggttggt gcggaacacc gtctcttcca ggttgcgctg gccgaggaac gaaccggtgt
    19441 tgacgtcgat ggtggtcatc gcctcggtct ggtcgatcac caggtagcca ccggatttca
    19501 gcggcacctg cttgtccagc gcgcggccga tctcgtcctc caccccgaac atgtcgaaga
    19561 tcgggcgatc accgctgtac agctcgatct tctcggccag caccggcatg tacttggcaa
    19621 caaaggcctg caactgcgcg aaggtctcct tggagtccac cttcaccttg tcaacgtcct
    19681 tgcggatcag gtcgcgtacc gatcgcagcg gcaggctcag gtcttcatag atgttgctgc
    19741 acgaggccgc ttcgcggcca cgacgctcga ccacgttcca aacgcgcgac aggtaggcga
    19801 tgtcctcggc gatggcctct gccggctggc cctcggcatt ggtacgcacg atgtagccgt
    19861 agcccccgtg ctgcgccgac agttcggtca ccagcgcctt caggcgggcg cgctcggttt
    19921 catcctcgat gcgtgcggaa acgcccacca ccttggattg cggcagcagc accatgtagc
    19981 gcgagggaat gctgatctgg gtggtcaggc gtgcgccctt ggtcccgatc gggtccttca
    20041 ccacctgcac cacgatgtcc tggccgtcgc gcagcagctc gacgatcggc acgctggacg
    20101 gcggcggcag cgtggtgttc tcggtatcgg cactggccac cggcgccggc cgcaccacgt
    20161 cgttggcatg caggaacgcg gcacgctcca gcccgacttc gacgaaggcc gcctgcatgc
    20221 cgggcatcac ccgctgcacc ttgcccttgt agatgttgcc gaccacaccc cggcgccaac
    20281 cgcgctcgat gtgcagttcc tgcagcatgc cgttctcgat caccgcgacc cgggtttcgc
    20341 gcggggtcac attgaccagg atttcctcag acatcggcag cctccctggc ggcatcggca
    20401 gttgtggccg gcacgccgca gcgcgccagc agacgatcgg tatgcagcaa tggcagcccc
    20461 atgacgccgg agtagctgcc ggaaagatgt tcgatccagc gctcggcccc gccctggatg
    20521 gcgtaggccc cggccttgtc caacggctcg ccggtggcca cgtaggcggc gatgtcggca
    20581 gcgccgatcg gggcgaaggt cacttcggaa atgaccagtt cgctgtccag cccgtccgcg
    20641 ccgaccacca ccacggcggt catcacctga tgggtacgcc cggcaaggcg cgccagcatc
    20701 gcccgcgcat cggcggcgtc agtgggcttt ccgaacacgt cgccatccag caccacctcg
    20761 gtgtccgagc cgagcacgcg cgcctgcggg tcatcggcca gcacccgggc cagcccggcg
    20821 cgcgccttgt cggcggcgac ccggcagaca tactgttcgg cgctttcagc gggcgcgcg
//
