LOCUS       NZ_CP067993            22898 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain DHHJ chromosome, complete
            genome.
ACCESSION   NZ_CP067993
VERSION     NZ_CP067993.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4682909)
  AUTHORS   Cao,Z.-J.
  TITLE     Genome Characterization of a novel Stenotrophomonas isolate with
            high keratinase activity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4682909)
  AUTHORS   Cao,Z.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2021) Bioengineering Department, Donghua
            University, North People Road, Shanghai 201620, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 336.0x
            Sequencing Technology             :: PacBio RSII; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016659185.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:56:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,314
            CDSs (total)                      :: 4,222
            Genes (coding)                    :: 4,196
            CDSs (with protein)               :: 4,196
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 10 of 26
            Pseudo Genes (incomplete)         :: 16 of 26
            Pseudo Genes (internal stop)      :: 0 of 26
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:47:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1650144
            Orig. end                         :: 1673042
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067993.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang-Jun Cao.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22898
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22898
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12898](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            456..1880
                     /locus_tag="JJL50_RS07655"
                     /old_locus_tag="JJL50_07655"
     CDS             456..1880
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661180.1"
                     /locus_tag="JJL50_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07655"
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_201118734.1"
                     /transl_table=11
                     /translation="MTQAQPGTASQGGENTAFIDLISCVATLGGFLFGFDSGVINGTVD
                     GLRQAFNSSEAALGFEVASMLLGCAIGAFLAGWLGDRLGRRGVLIVSALLFLVSALGAG
                     AAHASWLFIVARVLGGFAVGAASVMSPAYIAEVASSRYRGRLATVQQMAIICGLFAAFL
                     SNYLLARAAGASTEPLWLGQEAWRWMFWMQALPSGLFLLLLLVIPESPRFLVLKGRQQQ
                     ARAVLSRLYGEAAAATKQAEIEASLAQDQHKPRFSDLRDTVTGKLRPILWVGIGLAMFQ
                     QLVGINVVFYYGAVLWQAVGFSESDALLINVLSGALSIGACLLTVLLIDRIGRKPLLWI
                     GSVGMSVALVLMVVAFASGSLVDGRLQLSDGMGRLALVAANVYVVFFNMSWGPVMWVML
                     GEMFPNQIRGPALAVAGAAQWTSNFAITVTFPMLLAGIGLAGAYGIYAVAAILSIVFVV
                     RYVRETKGKELEQMEG"
     tRNA            complement(2408..2482)
                     /anticodon=(pos:complement(1652591..1652593),aa:Glu,
                     seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="JJL50_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="JJL50_07660"
                     /product="tRNA-Glu"
     gene            complement(2408..2482)
                     /locus_tag="JJL50_RS07660"
                     /old_locus_tag="JJL50_07660"
     misc_feature    2426..2441
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            2535..3914
                     /gene="pcnB"
                     /locus_tag="JJL50_RS07665"
                     /old_locus_tag="JJL50_07665"
     CDS             2535..3914
                     /EC_number="2.7.7.19"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pcnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416117.1"
                     /locus_tag="JJL50_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07665"
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="WP_049400939.1"
                     /transl_table=11
                     /translation="MGNPETSTGSANIISSATSPFSLRVIPRDQHTISRKDISPNALRV
                     LYRLRDAGFGAYLVGGAVRDLLVNGQPKDFDVATDATPEQVKQLFRNCRLIGRRFRLAH
                     VVFGREIIEVATFRANSDDGSGDREMENGMLVRDNVYGTIEDDAIRRDFTCNALYYAIE
                     DFSVRDYTGGFEDVQARLMKLIGDPEQRYREDPVRMLRAVRLAAKLGFQIEEGTAAPIP
                     HLAGLLNEAAPARLFEEVLKLFLSGHGVASFEGLERYGLLDVLFPESAKALKSNRTGAL
                     RRMLVEGLANTDARVANDEPVSPAFLFALLLWPAFCRAQATLLKQGVAPEEAQRRAADR
                     VTVQQLSTIALPRRFSLPMQEIWLLQSRFSSRQRKRVFRTLTHPRFRAAFDFLSLRQVA
                     SAEHAADVEFWREAQAQSGRELESSLDVMHSEEGGDESGAPRKRRRRRRRPGAPAGAAG
                     E"
     gene            3918..4403
                     /gene="folK"
                     /locus_tag="JJL50_RS07670"
                     /old_locus_tag="JJL50_07670"
     CDS             3918..4403
                     /EC_number="2.7.6.3"
                     /GO_function="GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338321.1"
                     /locus_tag="JJL50_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07670"
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="WP_201118735.1"
                     /transl_table=11
                     /translation="MTLAWIGLGANLGDAAVTVGAAIAALDGLPATRLRQASRLYATPA
                     WGNEDQPPFVNAVAAVETTLPADTLLQAMLALEQRFGRVRDPAVHWGPRALDLDLLLYG
                     AQVLDQPGLQVPHPYLHERAFVLVPLAEIAPDLAIPGHGRVRDAVMRVDACGIAPIG"
     gene            4438..5253
                     /gene="panB"
                     /locus_tag="JJL50_RS07675"
                     /old_locus_tag="JJL50_07675"
     CDS             4438..5253
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416119.1"
                     /locus_tag="JJL50_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07675"
                     /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
                     /protein_id="WP_005416119.1"
                     /transl_table=11
                     /translation="MSTHADSKPWTVPALAEAKRNGQKLVMLTAYDAGFARTFDANGVD
                     LILIGDSLGMVVQGHDSTLPVTVADMVYHTRAVARVLQRALLVADLPFGADATPERALD
                     ASLQLLQAGAEMVKIEGAGFKVDIIRYLVEREIPVCAHLGLTPQSVLRLGGFKIQGRGD
                     AARQLVEDAKAVAAAGASIMVLECVPTPVAAEVTAAVDVPTIGIGAGPQCDGQVLVLHD
                     FLGLDSGHRRPKFVKDFLAEGGSVAGATRAYADAVRDGSFPDEQHAYAQ"
     gene            5250..6089
                     /gene="panC"
                     /locus_tag="JJL50_RS07680"
                     /old_locus_tag="JJL50_07680"
     CDS             5250..6089
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011259031.1"
                     /locus_tag="JJL50_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07680"
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_201118736.1"
                     /transl_table=11
                     /translation="MIQTFNELGALRGQIAQWKREGLRVALVPTMGNLHGGHHSLVTLA
                     RQYADKVVASIFVNPTQFGPNEDFSRYPRTPEADVAGLEQADCDAVWLPSVEAMYPLGV
                     DKTTRMHAPGVSEVLEGASRPGHFDGVCTVVARLFLQVQPDVAVFGRKDYQQLAVIKQM
                     VAELSFPIQIVGAEIVRDEDGLAKSSRNQYLSAEQRPLATTIHRTLLGMREGYVAGQAR
                     DRIEADATAALQAAGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGSTRLIDNLEF"
     misc_feature    complement(6115..6129)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            6204..7145
                     /locus_tag="JJL50_RS07685"
                     /old_locus_tag="JJL50_07685"
     CDS             6204..7145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJL50_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JJL50_07685"
                     /product="hypothetical protein"
                     /protein_id="WP_201118738.1"
                     /transl_table=11
                     /translation="MITALVTTVVGALLVAGIFAAIKSRWLYVIAPKLYMNTPLSDGQV
                     VSITLVNQGLLEEEDVAVTFRQACKFELVATSKSTLLVSGKTLSVPRLSRFESVSVILL
                     FEGKAFDPVDIESIESKNTKGRVVENKEKATAFWQGVVAFPIAILALAVPFLFGTALGA
                     ETGVSAYGYVKDKVAEFSGEAKQLAGYESSLRDVSYSDRFKKSSQRRKVRVEPEEVLRR
                     GDVISLRTRIWNETDEVLTIEGYLKTSAGDRGSVDFWDTRVESFALGPGEDQVVTQKAF
                     LPDITKIKIIDNRFSFETMDGESMVLVRSIKF"
     misc_feature    6243..6245
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7122..7124
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             7148..7240
                     /gene="allorf_1657292_1657384"
                     /locus_tag="allorf_1657292_1657384"
                     /protein_id="allorf_1657292_1657384"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRAVNSACGRARVTARCVYESLHKDRNAAS"
     CDS_motif       7148..7174
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRAVNSACG"
                     /locus_tag="allorf_1657292_1657384_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7175..7240
                     /prepeptide="core"
                     /locus_tag="allorf_1657292_1657384_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="2349.6"
                     /monoisotopic_mass="2348.2"
                     /core_sequence="RARVTARCVYESLHKDRNAAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRAVNSACG"
                     /leader_location="[7147:7174](+)"
                     /alternative_weights="2367.6"
                     /alternative_weights="2385.7"
     gene            7506..7886
                     /gene="panD"
                     /locus_tag="JJL50_RS07690"
                     /old_locus_tag="JJL50_07690"
     CDS             7506..7886
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036943.1"
                     /locus_tag="JJL50_RS07690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07690"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_032128853.1"
                     /transl_table=11
                     /translation="MHLSLLKTKIHRATVTHSELNYEGSIAIDDNLLAATGIREFEQVH
                     IWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPK
                     LVYVDGKNQISHTNDTIPTQAA"
     gene            7883..9397
                     /gene="pgi"
                     /locus_tag="JJL50_RS07695"
                     /old_locus_tag="JJL50_07695"
     CDS             7883..9397
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300464.1"
                     /locus_tag="JJL50_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07695"
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_201118740.1"
                     /transl_table=11
                     /translation="MTTNNGFDSLHSHAQRLKGASIPSLLTAEPGRVQDLALRVGPLYV
                     NFARQKYDAAALQALLTLAADRDVGGAITRLFRGEQVNLTEGRAALHTALRGDVVDAPV
                     AAEAYATARGIRQRMGVLVRALEDSGVTDVVSVGIGGSDLGPRLVADALRPVTGARLRV
                     HFVSNVDGAAMQRTLATLDPAKTAGILISKTFGTQETLLNGQILHDWLGGSERLYAVSA
                     NPERAAKAFAIAADRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQMDAH
                     ALDAPLERNLPVLHGLTDIWNRNVLGHATHAVMTYDQRLALLPAYLQQLVMESLGKRVQ
                     RDGAPVTTDTVPVWWGGAGTDVQHSFFQALHQGTSIVPADFIGCVHNDDPYTINHQALL
                     ANLLAQTEALANGQSSDDPHRDYPGGRPSTLILLDALTPQALGALIAMYEHAVYVQSVI
                     WNINAFDQFGVELGKQLASGLLPALQGEDVAIADPMTREILAQLKG"
     misc_feature    9707..9725
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.17"
                     /tool="antismash"
     gene            9714..9920
                     /locus_tag="JJL50_RS07700"
                     /old_locus_tag="JJL50_07700"
     CDS             9714..9920
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268305.1"
                     /locus_tag="JJL50_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07700"
                     /product="DUF6229 family protein"
                     /protein_id="WP_049400943.1"
                     /transl_table=11
                     /translation="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAGATESALTSASD
                     TLITGGGTECTTTMSVVNHCLCC"
     CDS_motif       9714..9812
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGA"
                     /locus_tag="JJL50_RS07700_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9813..9920
                     /prepeptide="core"
                     /locus_tag="JJL50_RS07700_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="3219.6"
                     /monoisotopic_mass="3217.5"
                     /core_sequence="GATESALTSASDTLITGGGTECTTTMSVVNHCLCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGA"
                     /leader_location="[9713:9812](+)"
                     /alternative_weights="3237.6"
                     /alternative_weights="3255.6"
                     /alternative_weights="3273.6"
                     /alternative_weights="3291.7"
                     /alternative_weights="3309.7"
                     /alternative_weights="3327.7"
                     /alternative_weights="3345.7"
                     /alternative_weights="3363.7"
     gene            10001..12898
                     /locus_tag="JJL50_RS07705"
                     /old_locus_tag="JJL50_07705"
     CDS             10001..12898
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338325.1"
                     /locus_tag="JJL50_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07705"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_201118742.1"
                     /sec_met_domain="DUF4135 (E-value: 2.8e-79, bitscore:
                     265.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2e-33, bitscore:
                     113.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPAAAAFARITEHFLVDARTVLAAGLHDPAIDLRPDERALLH
                     EQGDAALREHAQLKLNRVLLLELHAAARGGDIGPLEGAGALDEFVALATGEGFHEHLQR
                     RYPVLLPRLSRMLEGQCAAVVELAARIGRDRALLTDLLGSPAGSLRAVSLGRGDLHGGG
                     RTVARLQFDGGTLMYKPRSLRIDATLDGLLEAVFGEGPGRVRVPRVVDRGSHGWAAFAE
                     HRYCSGDEELRAYYRGLGHWLAILRLVGGTDIHLENLIAVGPVPVVVDAESVFSQVIDV
                     EPSGLGDAYDTAVKLMRNSVLRTGIVPFRTTGLGMEGVDLSAAGALPGEQPRVQVPVII
                     EDGTAPARLGLVEAEVAIAQNHPSPQPDVSLYWDHISEGFVDASGRLRALDARGELMPL
                     LAGFEGCQVRDVRRPTMAYAELGRMLWHPASLHKEAQAVERAIDLLVRNAAVSPAAPSD
                     LETVRGEVDDLRHGDIPIFTSQLDATRIRSIADNWRAMRIDLEDVTIRSTLVATDLNQH
                     ALARAEARAGYSYAAQQPRADDLDLRRRTLAAHAVKNLLRLAVHGEDGSMTWITPEVTR
                     TGWTVQPVQPDLYFGLGGIAFALAAYRREVEQGRADPVAGLDPAIEGAIAVFQTMCERH
                     PAGIDGGFVGSGSQIWTLLALHDLLQRPALLALAERCAEGVERRGFQGPVKFELIDGVS
                     GMILPLLALAEATGRSRWLELAAAAGRRMQEAAIVDADGARWPTPQFREPIGGFGHGAM
                     GMGWALARLARSDAGSVPERAAWRQLAEGAFAFQAALFESHTGRWRDIHLEDGQKNFPT
                     WCHGSVGIGLAAADLYARTGDPAQLRDMRRAVADARGKWGFSHTLCHGDVSTRELLVLA
                     AALDPEGCPYPQDEAAIEIVSSIEEHRGMVGGLTRAAFTPGLMIGLAGTIYGFLRMHPA
                     CTLPSPLLQETVAARVDASASRSSAAQDRAVLAEV"
     gene            complement(12917..13486)
                     /locus_tag="JJL50_RS07710"
                     /old_locus_tag="JJL50_07710"
     CDS             complement(12917..13486)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012510702.1"
                     /locus_tag="JJL50_RS07710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07710"
                     /product="response regulator transcription factor"
                     /protein_id="WP_012510702.1"
                     /transl_table=11
                     /translation="MSLHHSTLGLLVDDDELYLRTLQRSLARKGLETQTAQDAASALAL
                     ARQHPPAFALIDLKLGSDSGLALIQPLRALRADMRILLVTGYASIATAVEAIKLGADDY
                     LPKPATVPMILRALGEEDDGPADDGEMEVPDAMTPISRLQWEHIQQAMHETGGNVSAAA
                     RLLGMHRRSLQRKLAKRPSPERDPSR"
     gene            complement(13483..14709)
                     /locus_tag="JJL50_RS07715"
                     /old_locus_tag="JJL50_07715"
     CDS             complement(13483..14709)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661188.1"
                     /locus_tag="JJL50_RS07715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07715"
                     /product="ATP-binding protein"
                     /protein_id="WP_032128856.1"
                     /transl_table=11
                     /translation="MTGPDAPFLRTLCSLRWLAVGGQAATILVATWVLGLPLPQLPLWA
                     GVAVLTLFNIYTQLRPEAADTAPLTAFGHILVDVIILTWMVGWSGGMANPFSSLFLILI
                     ALAAFALPLRWALAVALACLLGYAASGIFGQSLPDGYFRAQDLNRWGVVANFLISAAVV
                     LTFSTRLALALRQRELELSALRERFARNEGIVALATHAASVAHELNTPLATMTLLADDV
                     AERSEEPEVREDMETLRELLVQCRERVLALAAPASADAPGRSHSSAQQVLEQWRLVRPT
                     IDLHRNDDAPLRLPLDPGVGHLLMVLLNNAADAGEQAGRPRVDLDLRIEGDDLIGEVRD
                     YGHGFDARAAVLPGKLFGSSKSEGMGVGLALSHATIERLDGEMWMRPAQGAGSRVGFRL
                     PLTPREDTP"
     misc_feature    14779..14797
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.46"
                     /tool="antismash"
     gene            14824..16089
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="JJL50_RS07720"
                     /old_locus_tag="JJL50_07720"
     CDS             14824..16089
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300453.1"
                     /locus_tag="JJL50_RS07720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07720"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_201118743.1"
                     /transl_table=11
                     /translation="MHDAVTRPTPPSDATAWPRRQTHAVQIGGVTVGGGKPVVVQSMTN
                     TDTSDVASSVKQVAELWRAGSEMVRLTVNTVEAAAAIPRIVDKLAMMGIDVPLIGDFHY
                     NGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIRYHKPVRIGANWGSL
                     DQALAAKLMDENNLREQPWDAGRVLREALIRSALDSAEQAVELGLPRDRIVLSAKVSGV
                     QELIAVYRDLAQRSDFALHLGLTEAGIGSKGIVASSAALSVLLQEGIGDTIRISLTPEP
                     GQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAKVVQNHVREKMPLW
                     KIHHPGAENMTLAVMGCIVNGPGESRHANIGISLPGTGETPAAPVFVDGEKKVTLRGDN
                     IAQEFVALIDDYVEHKYVRSAG"
     gene            16070..16819
                     /locus_tag="JJL50_RS07725"
                     /old_locus_tag="JJL50_07725"
     CDS             16070..16819
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646755.1"
                     /locus_tag="JJL50_RS07725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07725"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_032128858.1"
                     /transl_table=11
                     /translation="MSEAPDKPAILAAPESASGFRHWMARNAWRLVLLFGGVLLPLAGF
                     VALADEVHEFESFHFDAPLLWQMHGLHSPLLDRFFVLISRLGYEWFLIPADVLIIGVLL
                     GYRRWREATFVAVSFVGSALLNMGSKHFFQRQRPSLWESIAPESTFSFPSGHAMGSMTL
                     AVTLVLLAWNTRWRWPVLLLAPAFSLLVSVSRVYLGVHYPSDILAGWCAALVWVVGCYL
                     VMFSRRHPWRRHGSPPAKASEASSQGD"
     gene            17021..17668
                     /locus_tag="JJL50_RS07730"
                     /old_locus_tag="JJL50_07730"
     CDS             17021..17668
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulator containing a CheY-like
                     receiver domain and an HTH DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011408972.1"
                     /locus_tag="JJL50_RS07730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07730"
                     /product="response regulator"
                     /protein_id="WP_004153112.1"
                     /transl_table=11
                     /translation="MTIRVYLVDDHALVRTGMKMILSGETDIEVVGEAETGEDALREVR
                     QLLPDVVLCDLHLPGVSGMEVTERIVRSHRNTRVVIVSVLEDGPLPKRLLEAGAAGYIG
                     KGCDAQELLRAVRDVAGGRRYLGTSIAQNLALSTVEGNGSPFDSLSPRELEVALLLTQG
                     LRQEDIARRLSLSAKTVNTHKARLFEKMGIHDNIALARMASQYGLVDPARPL"
     gene            complement(18003..18662)
                     /gene="eda"
                     /locus_tag="JJL50_RS07735"
                     /old_locus_tag="JJL50_07735"
     CDS             complement(18003..18662)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008700 - 4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /GO_process="GO:0009084 - glutamine family amino acid
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="eda"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265926.1"
                     /locus_tag="JJL50_RS07735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07735"
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_049423523.1"
                     /transl_table=11
                     /translation="MGIEQHQVKAAELLRAAGILPVVTIHTLDQARAVSAALLEGGLPA
                     IELTLRTPVAMEALAMLKRELPDVVVGAGTVLTVEQMQQSIDAGADFLVTPGTPPALAD
                     ALAAAPLPVVPGAATPTELLSLYARGFRVCKLFPATAVGGLAMIKGLAGPVADLKLCPT
                     GGITENTAAEYLEQKNVVCIGGSWMVPGNWIANGEWDKVRASATDAAKIIQRVRGH"
     misc_feature    complement(18630..18639)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    18686..18700
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.02"
                     /tool="antismash"
     misc_feature    complement(18687..18702)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.61"
                     /tool="antismash"
     gene            complement(18894..20810)
                     /gene="edd"
                     /locus_tag="JJL50_RS07740"
                     /old_locus_tag="JJL50_07740"
     CDS             complement(18894..20810)
                     /EC_number="4.2.1.12"
                     /GO_function="GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="edd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015472018.1"
                     /locus_tag="JJL50_RS07740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07740"
                     /product="phosphogluconate dehydratase"
                     /protein_id="WP_049423525.1"
                     /transl_table=11
                     /translation="MSLHPQLQAITQRVIRRSAASRAAYLAAIDASLREGPFRSRLSCG
                     NLAHGFAACGGTDKSRLRGGVTPNLGIITAYNDMLSAHQPFETYPEQIREIARELGATA
                     QVAGGVPAMCDGVTQGRGGMELSLFSRDVIAQATAIGLSHDMFDTTVYLGVCDKIVPGL
                     LIGALAFGHLPAVFVPAGPMTPGIPNKQKAEVRERYAAGEATREELLEAESASYHGAGT
                     CTFYGTANSNQVLLEAMGVQLPGASFVNPGTPLRDALTREATERALDITALGEDFRPLG
                     RIIDERAIINAVIALMATGGSTNHTIHWIAVARAAGIVLTWDDFDELSQLIPLLARVYP
                     NGEADVNRFAAAGGPAFVFGELIKAGLMHGDLVSVARGGMADYAREPQLRDGKLVYLPG
                     LERSADEEVVRGVDNPFEHQGGLRLLRGNLGKSLIKLSAVKPQYRTIEAPAVVVDAPQV
                     LNKLHAGGLLPEHFVAVVRYQGPRANGMPELHSLAPLLGLLQNQGRRVALVTDGRLSGA
                     SGKIPAAIHVTPEAARGGPLAKVREGDMIRLDGEAGTLEVLVDAAEWAARPLAPNTAPA
                     AHDLGRNLFAINRRVVGPADQGAISISCGPAAADGGPWEYDAEYELGHDAAAAAAPHEA
                     KDA"
     misc_feature    complement(20770..20783)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.82"
                     /tool="antismash"
     gene            complement(20869..21594)
                     /gene="pgl"
                     /locus_tag="JJL50_RS07745"
                     /old_locus_tag="JJL50_07745"
     CDS             complement(20869..21594)
                     /EC_number="3.1.1.31"
                     /GO_function="GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgl"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479767.1"
                     /locus_tag="JJL50_RS07745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07745"
                     /product="6-phosphogluconolactonase"
                     /protein_id="WP_049423528.1"
                     /transl_table=11
                     /translation="MSPTTFHDDRIEFIQHGDADGWIEAVAAEMAQTLNHDINEVGRAR
                     ILLSGGTTPAPVYQALAELDVHWDRVEVSLADERWLSPQDRDSNAWLVRENLLKRAEGA
                     HFDPLVRIGKPLPECVYTANLQAQHSQPPSLVALGMGNDGHTASLFPGSKDLARALEST
                     LPYAALDATGCPGANQWPLRITLTPHGLRQCRQRLLLLRGKQKLQVLRQALDSNDAQQY
                     PILNAINLDGARLRVHWAD"
     gene            complement(21591..22598)
                     /gene="glk"
                     /locus_tag="JJL50_RS07750"
                     /old_locus_tag="JJL50_07750"
     CDS             complement(21591..22598)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416128.1"
                     /locus_tag="JJL50_RS07750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_07750"
                     /product="glucokinase"
                     /protein_id="WP_049400948.1"
                     /transl_table=11
                     /translation="MSASSQPVLVADIGGTNARFALADTSQDAPLQKDSIREYAVAEFP
                     SLGDAARHHLEQIGATASRGVFAVAGRVDGDEARITNHPWVISRSRTAAMLGFNELHLI
                     NDFAAQAMAISLLQPDDVVQVGGAAWVPGKPGQPRNYAVIGPGTGLGVGGLILRHGRCY
                     PLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRAVCEMAGIDPG
                     QLQPVDVTARALHGDPQAMRTVDVFCAVFGAIAGDLVLTQGAWDGVFLTGGLTPKMLDS
                     LQHSGFRQRFEHKGRFSSIMARVPSLAVMHPHAGLLGAAAYAADAERDAPGVAA"
     misc_feature    complement(22800..22815)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    22801..22814
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.0"
                     /tool="antismash"
ORIGIN
        1 cgggtccttg cgcacggtca gtaccggcca ctccttcgcc agctcggcgt tgagggcgac
       61 gaagctctcc tggccggcag gaacatcgtc ctccgggaag atcgcattga ccgggcattc
      121 cggttcgcag agggtgcagt cgatgcactc atccgggtcg atcaccagga agttcgggcc
      181 ttcgtggaag caatccacgg ggcatacttc cacgcaatcg gtgtgtttgc acttgatgca
      241 gttttcggtg acgacaaagg gcatgggctg ggggtggatc gattcctgaa cccgccaatt
      301 ctagaacagg ttgggccccg gtgtcggcgc ggggcggaaa acgggtgtct ggcaggctcg
      361 gctgcgcccc cgttggcgac agggcggggc ctgtgcgacg ctgcgggcgc ccggtcgccg
      421 caggtggccg ctttcccttc ccagcaggat cgtccatgac ccaagcccag cccggcaccg
      481 cctcccaggg cggcgagaac actgcgttca tcgacctcat cagctgtgtg gccaccctcg
      541 gtggattcct gttcggtttc gatagtggtg tcatcaacgg tacggtcgac ggcctgcgcc
      601 aggccttcaa ttccagcgaa gcggcgctcg gtttcgaagt cgcctcgatg ctgctgggct
      661 gtgcgatcgg cgcgttcctg gccggttggc tgggtgaccg gctgggccgc cgtggcgtgc
      721 tgatcgtgtc ggcactgctg ttcctggtgt cggcgctggg tgccggcgcc gcccatgcct
      781 cctggttgtt catcgtcgcg cgcgtgctgg gtggctttgc ggtgggtgcg gccagcgtga
      841 tgtcgccggc ctacattgcc gaagtcgcct cgtcacgcta tcggggacgg ctggccacgg
      901 tgcagcagat ggccatcatc tgtggcctgt tcgctgcctt cctcagcaac tacctgctgg
      961 cacgtgccgc cggtgcgtcc accgagccgc tatggctggg ccaggaggcc tggcgctgga
     1021 tgttctggat gcaggcactg ccgtcggggc tgttcctgct gttgttgctg gtgatcccgg
     1081 aaagcccgcg ctttctggtc ctgaaggggc gtcagcagca ggcgagggcg gtactgtcgc
     1141 ggctgtacgg cgaggcggcc gcggcgacca agcaggccga gatcgaagcc agcctggccc
     1201 aggatcagca caagccgcgc ttcagcgacc tgcgcgatac ggtcaccggc aagctgcgcc
     1261 cgatcctctg ggtaggcatt ggcctggcca tgttccagca gctggtcggc atcaacgtgg
     1321 tgttctatta cggcgcggtg ctgtggcagg cggtgggctt ctcggaaagc gacgcgctgc
     1381 tgatcaacgt gctgtccggc gcgctgagca tcggcgcctg cctgctgacg gtgctgttga
     1441 tcgaccgcat cgggcgcaag ccgctgctgt ggatcggctc ggttggcatg tcggtggcgc
     1501 tggtgctgat ggtggtggca tttgccagcg gcagcctggt cgatggtcgc ctgcagctgt
     1561 ccgatggcat gggccggctg gcgctggttg cggccaacgt ctatgtggtg ttcttcaaca
     1621 tgtcctgggg cccggtgatg tgggtgatgc tgggcgagat gttccccaac cagatccgcg
     1681 gcccggcgtt ggccgttgcc ggtgcggcgc agtggacgtc gaatttcgcg atcaccgtga
     1741 ccttcccgat gctgctggcc ggcatcggcc tggccggcgc ctatggcatc tacgcggtcg
     1801 ccgcgatcct ctcgatcgtt ttcgtggtcc gctacgtacg cgagaccaag ggcaaggagc
     1861 tggagcagat ggaaggctga cgctacccgg cttcggttgc atcctgttgg cgcctggttg
     1921 tcccgagttt gagggggcag gccgccctct ccaggacacg caaaagccca tccatggtgc
     1981 tcgatggcgc catccatggc gccaacggtc ctggagaggg cggcctgccc cctcctgaca
     2041 gtttcatggt gcgtgcggac gcggtgaagc gctggtcggt tgttgccggg ggtcgcggga
     2101 aaccgtccag agccggtggg gtcacccagg gccggaccgt tggcgccatg ggttgggcgc
     2161 atgcacccga cgggttgggc aggagcccaa ccccggtctt gccgtgtgcg caggacagcg
     2221 cacgcgagca aggcgccatc gagcccccat ggatgggttc acggcgtgtc ctgccctggg
     2281 tgaccccacc ggctcaagcc gattgcaggg agacgccaat gcgaccaagt cgaccgacgc
     2341 catcacaacc ccggaaaaca gaaaagcccg cacaaaggcg ggctttttcg gttcctgctg
     2401 cggcgactgg cgctccctag gggactcgaa cccctgtttt agccttgaga gggccacgtc
     2461 ctaaccacta gacgaaggga gcgtaactgt gtcgctgccg aggcaggagc gctagtatat
     2521 gcacctcgat gccattgggc aatcccgaaa cttcaaccgg aagcgccaac atcatttcct
     2581 ctgctacatc accgttcagc ctgcgcgtca tcccgcgcga ccagcacacg atctcccgca
     2641 aggacatcag cccgaacgcc ctgcgcgtgc tttatcgcct gcgcgatgcc ggcttcggcg
     2701 cctaccttgt cggcggcgcg gtgcgcgatc tgctggtcaa tggccaaccc aaggatttcg
     2761 acgtggccac cgacgccacg cccgaacagg tcaagcagct gttccgcaac tgccgcctga
     2821 tcggtcgccg gttccgcctc gcccacgtcg tgttcggccg cgagatcatc gaagtcgcca
     2881 ccttccgtgc caacagcgat gacggcagcg gcgaccgcga gatggaaaac ggcatgctcg
     2941 tgcgcgacaa cgtgtacggc accatcgaag acgacgccat ccgccgcgac ttcacctgca
     3001 acgccctgta ctacgccatc gaggacttct cggtgcgtga ttacaccggc ggcttcgagg
     3061 atgtccaggc gcgcctgatg aagctgatcg gcgaccccga gcagcgttat cgcgaagatc
     3121 cggtgcgcat gctgcgtgcg gtgcgcctgg cggccaaact cggcttccag atcgaggagg
     3181 gcaccgccgc gccgatcccg cacctggcgg gcctgctcaa cgaagccgca ccggcgcgcc
     3241 tgttcgaaga agtgctcaag ctgttcctgt ccgggcacgg cgtggccagc ttcgaaggcc
     3301 tcgaacgtta cggcctgctg gacgtgctgt tcccggagag cgccaaggcg ctgaagtcca
     3361 accgcaccgg cgcgctgcgc cgcatgctgg tggagggcct ggccaacacc gatgcacgcg
     3421 tggccaacga tgaaccagtc tcgcccgcgt tcctgtttgc gctgctgctg tggccggcgt
     3481 tctgccgcgc ccaggcaacc ctgctcaagc agggcgtggc accggaagag gcgcagcgcc
     3541 gtgcggccga ccgcgtcacg gtgcagcagc tgagcaccat cgcgctgccg cgccgcttct
     3601 cgctgccgat gcaggaaatc tggctgctgc agtcgcgctt cagctcgcgc cagcgcaagc
     3661 gcgtgttccg taccctgacc catccgcgct tccgcgctgc gttcgacttc ctcagcctgc
     3721 gccaggtggc ctcggccgag cacgccgccg atgtcgagtt ctggcgtgag gcgcaggcgc
     3781 agtccggtcg cgagctggaa tcgtcgctgg acgtgatgca cagcgaagag gggggtgacg
     3841 agagcggggc accgcgcaag cgccgccgtc gccgccgtcg tccgggtgcc ccggccggtg
     3901 cggctggcga gtaaacgatg acccttgcct ggatcggcct cggcgccaac cttggcgacg
     3961 cggccgtcac cgtcggcgcg gcgattgccg cgctcgacgg cctgcctgct acacgcctgc
     4021 gccaagcctc aaggctgtac gccacgccgg cctggggcaa tgaagaccag ccgccgttcg
     4081 tcaacgcggt ggctgcggtc gagaccacgc tgcccgccga tacgctgctg caggcgatgc
     4141 tggcgctgga gcagcgtttt ggtcgcgtac gcgatccggc ggtgcactgg ggcccgcgcg
     4201 cgctggacct ggacctgctg ctgtatggcg cgcaggtgct cgaccagcct ggtctgcaag
     4261 tgccgcatcc ttacctgcac gagcgtgcct tcgtgttggt gccgctggcc gaaatcgcgc
     4321 cggatctggc cattcccggc catggccgcg tgcgggatgc agtgatgcgg gtggatgcct
     4381 gcgggattgc gccgataggg tgataatgcc cgggttatct cccccggtta tcagcacatg
     4441 agcacccacg cagacagcaa gccctggacc gttcccgccc tggccgaggc caagcgcaat
     4501 ggccagaagc tggtcatgtt gaccgcctac gacgccggct tcgcccgcac tttcgatgcc
     4561 aacggcgtcg acctgatcct gatcggcgat tctctgggca tggtcgtgca gggccatgat
     4621 tcgaccttgc cggtgaccgt ggccgacatg gtctaccaca cccgcgccgt ggcccgcgtg
     4681 ctgcagcgtg cgttgctggt ggccgacctg ccgttcggcg ccgatgccac cccggagcgc
     4741 gcgctggatg cctcgttgca gctgctgcag gccggcgccg agatggtcaa gatcgaaggt
     4801 gccggcttca aggtcgacat catccgctac ctggtggagc gcgagattcc ggtctgcgcg
     4861 catctgggcc tgaccccgca gtcggtgctg cgactgggcg gcttcaagat ccaggggcgt
     4921 ggcgatgccg cgcgccagct ggtggaagat gccaaggctg tggccgctgc cggcgccagc
     4981 atcatggtgc tcgaatgcgt gccgactccg gtcgccgccg aagtgaccgc tgcggtggat
     5041 gtgccgacca tcggcattgg cgcaggcccg cagtgcgatg gccaggtgct ggtgctgcat
     5101 gatttcctcg gcctggacag tggtcatcgc cgtcccaagt tcgtcaagga tttccttgcc
     5161 gaaggcggtt cggtggccgg tgccacccgc gcctatgccg acgccgtgcg cgacggcagc
     5221 ttccccgacg aacagcacgc ctacgcccaa tgatccagac cttcaacgag ctcggcgcac
     5281 tgcgcgggca gatcgcccag tggaagcgcg agggcctgcg ggtggcgctg gtgccgacca
     5341 tgggcaacct gcatggaggt caccattcgc tggtgaccct ggcccgccag tacgccgaca
     5401 aggtggtggc gagcatcttc gtcaacccga cccagttcgg gccgaatgaa gacttcagcc
     5461 gctacccgcg cacgcccgag gccgacgtgg ccgggctgga gcaggccgac tgcgatgccg
     5521 tgtggctgcc cagtgtggag gcgatgtatc cgctgggcgt ggacaagacc acgcgcatgc
     5581 acgcgccggg tgtcagtgaa gtgctggaag gcgccagccg tccgggtcac ttcgatggcg
     5641 tgtgcacggt ggtggcgcgg ctgttcctgc aggtgcagcc ggacgtggcc gtgttcggcc
     5701 gcaaggacta ccagcagctt gccgtgatca agcagatggt ggctgagctg tcgttcccga
     5761 tccagatcgt tggtgcggag atcgtgcgtg acgaggatgg cctggccaag agttcgcgca
     5821 accagtacct gagcgccgaa cagcgcccgc ttgcgaccac catccaccgc accctgctgg
     5881 gcatgcgcga aggctacgtg gccgggcagg cacgtgatcg catcgaggcc gacgccacgg
     5941 cggcattgca ggcggccggt ttccaggtcg actatgcggt gctgcggacc ccggagctgg
     6001 ccgagccgac cttcgacggc ggtggccgcg tggcgctgat tgccgcccgc ctgggcagca
     6061 cccggttgat cgacaacctg gaattctgag gcagtaccta ggctagatct acccatcgct
     6121 gtctttgatt cttggggtgg tctcagttgt tgagaccacc ccatccgaca attcattatc
     6181 tttaagctca aatggagggg ggtttgatta cggcgctggt aactactgtt gtgggtgctc
     6241 ttttagtggc gggaatcttc gctgccatca agagtcggtg gctctatgta atcgccccca
     6301 agttgtacat gaacactcct ttgagtgacg ggcaggtcgt ctcgatcacc ttggtaaatc
     6361 agggtctttt ggaggaggag gatgtcgccg ttacttttcg gcaggcctgt aaatttgagc
     6421 ttgtcgccac gtcgaagagc acgcttctag tatcaggtaa gaccctgtcc gttcccaggc
     6481 tgtctaggtt tgaatcagtc tctgtcatct tgcttttcga gggtaaggcc ttcgacccag
     6541 tggatatcga aagtattgag tcgaagaata cgaaaggtcg cgtggtcgaa aacaaagaaa
     6601 aagcgactgc gttctggcag ggggttgtcg cttttcccat tgctatcctt gctcttgcag
     6661 ttccgtttct ctttggcacc gccttggggg ctgaaacagg ggtttcggca tacggatatg
     6721 taaaggataa ggtcgcagag tttagtggtg aggccaagca gctcgcgggt tatgagtcaa
     6781 gccttcgtga tgtttcctat agtgatcgct tcaaaaaatc ttcccagcgg aggaaggttc
     6841 gtgtcgagcc ggaggaagtg ctgcggcgcg gtgatgtgat ttcgcttagg acgcgaattt
     6901 ggaacgaaac tgatgaagtt ttgacaattg agggctacct aaagacaagc gccggggatc
     6961 gcggctctgt agatttttgg gatactaggg tggagtcctt tgcactgggt cctggcgagg
     7021 atcaggttgt aacgcagaag gctttccttc ctgatatcac gaagattaag atcatcgata
     7081 ataggtttag tttcgaaacc atggatggtg agtcgatggt tttagttcgc tcaattaaat
     7141 tctaactgtg agagctgtta acagtgcttg tggcagagcg agagtgacag cgagatgcgt
     7201 atacgaatcg ctgcataagg atcggaatgc agcttcgtga ttcgctctgt atggttgaat
     7261 tgattgacct tcgacggcgg cggccgggtg gcgctgattg ccgcccgcct gggcagcacc
     7321 cgcttgatcg acaacctgga attctgagtt ccgcacgttg ggtggcgcca ggccatgcgc
     7381 ggcggactgc ggccgctgcg ctcgccgggc accgcccggc gctacctgaa caagttgcca
     7441 gccgtgatgc ccggcgccac gcgggtgcta gaatccgctc tttcctttgc cgttgcagcg
     7501 cccccatgca cctgtccctg ctcaagacca agatccaccg cgccaccgtc acccattccg
     7561 agctgaacta cgaaggctcg atcgccatcg atgacaacct gctggctgcc accggcatcc
     7621 gcgagttcga gcaggtgcac atctgggacg tgaccaacgg tgcgcgcttc tcgacctacg
     7681 ccatccgcgc cgaagccggc agcggcgttg tctcgctcaa cggtggtgct gcgcgccacg
     7741 tgcaggtcgg tgacatcatc atcatcgccg cgttcgccag catgaccgag caggaagctg
     7801 acagcttcaa gccgaagctg gtgtacgttg atggcaagaa ccagatctcc cataccaacg
     7861 acacgatccc gacccaggcc gcatgacaac gaacaacgga ttcgactcgc tgcattccca
     7921 cgcccagcgc ctgaagggcg caagcattcc cagcctgctc accgccgaac ccggccgcgt
     7981 gcaggacctg gcgctgcggg tcggtccgtt gtacgtcaac ttcgcgcggc agaaatacga
     8041 tgccgcggcg ttgcaggccc tgctcacgtt ggccgccgac cgtgatgtcg gtggtgccat
     8101 cacccgcttg ttccgtggcg agcaggtcaa cctgaccgaa ggtcgcgccg cgctgcatac
     8161 cgcgctgcgc ggcgacgtgg tcgatgcgcc ggttgcagcc gaggcctatg ccaccgcgcg
     8221 cgggatccgc cagcgcatgg gcgtgctggt gcgcgcgctg gaagacagtg gcgtgaccga
     8281 tgtggtcagt gtcggcatcg gtggttccga ccttggcccg cgtctggtcg ccgacgcgct
     8341 gcgtccggtc accggtgcgc gcctgcgcgt gcatttcgtg tcgaacgtgg acggcgccgc
     8401 catgcagcgc acgctggcca cgctggatcc ggccaagacc gccggcatcc tcatctccaa
     8461 gacctttggt acgcaggaaa ccctgctcaa cggccagatc ctgcacgact ggctgggcgg
     8521 cagcgagcgc ctgtatgcag tcagcgccaa tccggaacgt gccgcgaagg ccttcgcgat
     8581 cgccgccgat cgcgtgctgc cgatgtggga ctgggtcggt ggccgttatt cgctgtggtc
     8641 ggcggtcggt ttcccgatcg cgctggcgat cggcttcgag cgcttcgagc agctgctgga
     8701 aggcgcggcg cagatggatg cgcatgcgct ggatgcaccg ctggagcgca acctgccggt
     8761 gctgcacggc ctgaccgaca tctggaaccg caacgtgctg ggccatgcca cgcatgcggt
     8821 gatgacctac gaccagcgcc tggcgctgct gccggcctat ctgcagcagc tggtgatgga
     8881 aagcctgggc aagcgcgtgc agcgtgatgg tgcgccggtc accaccgaca ccgtgccggt
     8941 gtggtggggc ggggcaggca ccgacgtgca gcacagcttc ttccaggcgc tgcaccaggg
     9001 caccagcatc gttccggccg acttcattgg ctgcgtgcac aacgatgatc cctacacgat
     9061 caatcaccag gccctgctgg ccaacctgct cgcacagacc gaggcactgg ccaatggcca
     9121 gagcagcgat gatccgcacc gtgattaccc gggcggtcgc ccgagcacgc tgatcctgct
     9181 cgacgcgctg accccgcagg cgctgggtgc gctgatcgcc atgtacgaac acgccgtgta
     9241 cgtgcagtcg gtgatctgga acatcaatgc cttcgaccag ttcggtgtcg agcttggcaa
     9301 gcagttggcc agtggcctgt tgccggcgct gcagggtgag gatgtggcga ttgccgatcc
     9361 gatgacccgc gagatcctgg cgcagctgaa gggctgaccc ggcctgcgga tgtgccggcg
     9421 ccggccggcc atccgatgcc tctggggttg ccttcgatcc ggtcgcgcag gaatggcggc
     9481 gcggccactc attccacgtc acttccgtac cgcacgtgca gcgtattcgt gcgccctgcc
     9541 gcagcgcagc ttgacgcact tcgcacgcgg atgcagtgtg cacgggcggc tgtacctgtc
     9601 atccagtatc gctcgcagca tgatgttgat gccagggact ggccgtatcc gaagggacgt
     9661 ggaatcgatc catgtcctca acgcctcatg ttgtgaatga caggagattg cgaatggatc
     9721 tgaacgacga tgttgtgtcc ggctggctca atggctcgga cgatgtggat gggtgtgcca
     9781 accctgcggg ttcgctgttc atctatggcg ctggggccac cgagtccgcg ctcacgtcgg
     9841 cctccgacac cctgatcacc ggtggcggta ccgagtgcac caccacgatg tcggtggtca
     9901 atcactgcct gtgctgttga tgtagcccga gccggcacgc agcggcttgc gctgcgtgcc
     9961 ggcgactgga acagactctg gacactttgc agggggcgta atgaccgctt ctccggctgc
    10021 ggccgcgttt gcgcgcatca ccgaacattt tcttgtcgac gcgcgcacag tgttggcggc
    10081 tggcctgcat gaccccgcca tcgatctgcg gccagacgag cgcgcactcc tgcatgagca
    10141 gggcgatgcg gcgcttcgtg aacatgccca gctcaagctc aaccgcgtac tgctgctgga
    10201 actgcatgcg gccgcgcgcg gtggtgacat cggcccgctt gagggcgccg gtgcgctgga
    10261 cgaattcgtg gccctcgcca ccggcgaggg cttccatgag catctgcagc gacgctaccc
    10321 ggtgctgctg ccgcgactgt cgcgcatgct cgaaggacaa tgtgcggctg tggtggagct
    10381 ggccgcgcgc atcggccgtg atcgtgcgct gctgacggac ctgctcggca gtccggcagg
    10441 atcgctgcgt gcggtgtcgc tggggcgcgg tgacctgcac ggtggcggcc ggaccgtggc
    10501 gcggttgcag ttcgacggcg gtacgctgat gtacaagccg cgctcgctgc gcatcgatgc
    10561 cacgcttgat ggcctgcttg aagccgtctt cggcgagggc cctggccggg tacgcgtgcc
    10621 gcgcgtggtg gatcgtggca gccacggctg ggctgcattt gccgagcacc gttattgttc
    10681 cggtgacgaa gagctgcgcg cctactaccg cggtctcggt cactggctgg ccatcctgcg
    10741 cctggtgggc gggaccgaca tccatctgga gaacctgatc gcggtcgggc cggtgccggt
    10801 ggtggtcgac gccgaaagcg tgttctcgca ggtcatcgac gtcgaaccat ccggtctggg
    10861 cgatgcctat gacacggcag tcaagctgat gcgcaattcg gtgctgcgca ccggtatcgt
    10921 gccgttccgc accaccggcc tcggcatgga aggcgtggac ctgtccgccg ccggcgcact
    10981 gccgggcgag cagccgcgtg tgcaggtgcc ggtgatcatc gaagacggga cggcgccggc
    11041 gcggctgggc ctggtcgagg cagaggtcgc catcgcacag aaccatccga gcccgcagcc
    11101 cgatgtgtcg ttgtactggg atcacatcag cgagggtttc gtcgatgcca gcgggcgcct
    11161 gcgtgcgctg gatgccaggg gcgaactgat gccgttgctg gccggtttcg aaggctgcca
    11221 ggtgcgcgat gtgcggcggc cgaccatggc ctacgccgag ctcgggcgga tgctctggca
    11281 tccggcatcg ctgcacaagg aagcccaggc ggttgaacgc gcgatcgatc tgctggtgcg
    11341 caatgcagcg gtgtcaccgg ctgcgccatc ggacctggaa accgtacgtg gagaagtgga
    11401 cgacctgcgc cacggtgaca ttccgatctt cacttcacag cttgacgcga cccgcatccg
    11461 ctccatcgcc gacaactggc gtgcgatgcg catcgacctc gaagacgtga ccatccgcag
    11521 cacgttggtg gccaccgacc tgaaccagca cgcgctggcc cgcgccgagg ctcgggccgg
    11581 ctatagctac gccgcgcagc agcctcgcgc ggacgatctg gacctgcgcc gacgaacgct
    11641 tgcggcacac gcggtgaaga atcttctgcg gcttgccgtg cacggtgaag acggttcgat
    11701 gacctggatc acgcccgagg tgacccgcac aggatggacc gtccagccgg tgcagcccga
    11761 cctgtatttc gggctgggag gcattgcgtt cgcgctggcg gcctaccgcc gggaagtgga
    11821 gcagggacgt gccgatccgg tggctgggtt ggatccggcc atcgaaggcg ccattgcggt
    11881 gttccagacc atgtgcgagc gccatcccgc cgggatcgat ggtggtttcg tcggctcggg
    11941 ctcgcagatc tggaccctgc tggcattgca tgatctgctg cagcgccccg cactgctcgc
    12001 gctggccgag cgctgtgcgg aaggagtgga acgtcgtggt ttccaggggc cggtgaaatt
    12061 cgaactgatt gatggcgtgt ccggcatgat cctgccgttg ctggcgctgg ccgaggccac
    12121 cggcagatcg cgctggctgg agttggcggc tgcagccggg cgccgcatgc aggaagcagc
    12181 gatcgtcgat gccgacggcg cacgctggcc gacgccacag ttccgcgagc cgatcggtgg
    12241 ctttggccac ggcgcgatgg gcatgggctg ggcgctggca cggctggcgc gttcggatgc
    12301 cggcagcgtg cctgagcggg ccgcctggcg gcagctggcc gaaggagcct ttgcgttcca
    12361 ggcggcgctg ttcgagtcgc ataccgggcg ctggcgcgat atccacctgg aggacgggca
    12421 gaagaatttc ccgacctggt gccatggcag tgttggcatc ggtctggcgg cggcggatct
    12481 gtacgcccgc accggcgatc ccgcgcagtt gcgtgacatg cggcgggctg tggccgacgc
    12541 gcgcggcaaa tgggggttca gccacaccct gtgccatggc gatgtgtcca cccgggagtt
    12601 gctggtgctg gcggctgcgt tggatccgga ggggtgtccc tatccgcagg acgaggccgc
    12661 catcgagatc gtttcttcga tcgaggagca ccggggcatg gtcggcgggc tgacccgcgc
    12721 ggcctttact ccgggcctga tgatcggtct ggcaggtacg atctatggct tcctgcgcat
    12781 gcatccggcc tgcacgctgc cgtcgccgct gctgcaggag acggtagcgg cgcgggtcga
    12841 tgcgtcggcg tcgcgctcca gcgccgcgca ggaccgagca gtgctggccg aggtctgagc
    12901 cggacgggtc cggcgatcaa cggctgggat cgcgttccgg gctcggccgc ttggccagct
    12961 tgcgctgcag cgaacgccgg tgcatgccga gcaggcgggc ggctgcggac acgttgccgc
    13021 cggtctcgtg catcgcctgc tggatgtgtt cccactgcag gcggctgatc ggcgtcatcg
    13081 catcaggcac ttccatttca ccatcgtcgg ccgggccgtc gtcttcctcg ccgagcgcgc
    13141 gcaggatcat cggcaccgtg gccggcttcg gcaggtagtc gtcggcaccg agcttgatcg
    13201 cctccacggc ggtggcgatg ctcgcgtagc cggtcaccag caggatgcgc atgtccgcgc
    13261 gcagggcacg cagcggctgg atcagtgcca ggccggaatc gctgcccagc ttcaggtcga
    13321 tcagcgcgaa cgccggcgga tgctggcggg ccagcgccag cgcactggcg gcatcctgtg
    13381 cggtctgcgt ttcaagcccc ttgcgggcca ggctgcgctg cagggtgcgc aggtacagct
    13441 cgtcgtcgtc gaccagcagg cccagggtgg agtgatgaag gctcatgggg tgtcctcacg
    13501 tggggtcagc ggcaggcgga agccgacgcg gctgccggcc ccctgggccg ggcgcatcca
    13561 catctcgccg tcgaggcgtt cgatggtggc atgggacagg gccaggccga cgcccatgcc
    13621 ctcgcttttg ctgctgccga acagcttgcc cggcagcacc gcggcacggg cgtcgaagcc
    13681 gtggccgtag tcgcggactt cgccgatcaa gtcgtcgcct tcgatgcgca ggtccaggtc
    13741 cacgcgcggc cggccggcct gttcgccggc atcggcggca ttgttgagca ggaccatcag
    13801 cagatggccc acgcccgggt cgagtggcag ccgcagcggc gcatcgtcat tgcgatgcag
    13861 gtcgatggtc ggccgcacca ggcgccactg ttccagtacc tgctgggcgc tggagtggct
    13921 gcgacccggt gcatcggccg aggccggtgc ggccagcgcc agcacgcgct cgcggcactg
    13981 caccagcagc tcgcgcaggg tttccatgtc ttcgcgtact tcgggctctt cgctgcgctc
    14041 ggcgacgtca tcggcgagca gcgtcatggt cgccagcggc gtgttcagtt catgcgccac
    14101 cgaggcggca tgggtggcca gggcgacgat gccctcgttg cgggcgaagc gttcgcgcag
    14161 ggccgacagt tccagttcgc gctggcgcag cgccagtgcc aggcgggtgg aaaaggtcag
    14221 cacgaccgct gcggaaatca ggaaattggc gaccacgccc cagcggttga ggtcctgggc
    14281 gcggaaatag ccatccggca gcgactggcc gaagatgccg ctggcggcgt agccgagcag
    14341 gcaggccagc gccaccgcca gtgcccagcg caggggcagg gcgaacgcgg cgagcgcgat
    14401 caggatcagg aacagcgaac tgaacgggtt ggccatgccg ccactccagc ccaccatcca
    14461 ggtcaggatg atcacgtcca ccagaatgtg gccgaacgcg gtcagtggcg cggtgtcggc
    14521 cgcctccggg cgcagctggg tgtagatgtt gaacagggtc agcacggcca cgcccgccca
    14581 caatggcagt tgcggcaacg gcaggcccag cacccaggtg gcaaccagga tggtggcggc
    14641 ctggccacct acggcaagcc agcgcaggct gcacagggtt cggagaaacg gggcgtcggg
    14701 accggtcatt cacgctcatc gtatgcgttc acgcgtgacc gtgcctgcga caatcggccg
    14761 cagccgtgcc gccggctgaa tgcgagtcac ccggaatgcg gaggcgggcg gtagaatgcg
    14821 cccatgcacg acgccgttac ccgcccgacg cccccttccg atgccactgc ctggccccgc
    14881 cgccagaccc atgccgtcca gatcggcggg gtcaccgtag gcggaggcaa gccggtcgtg
    14941 gtgcagtcga tgaccaacac cgatacctcc gacgtggcct ccagcgtgaa gcaggtggcc
    15001 gagttgtggc gtgcgggttc ggaaatggtg cggctgaccg tcaacaccgt ggaagcggct
    15061 gcggcgatcc cgcgcattgt cgacaagctg gcgatgatgg gcatcgacgt gccgctgatc
    15121 ggtgacttcc attacaacgg ccatcagctg ctgaccgccg aaccggcctg tgccgaagcg
    15181 ctggccaagt accgcatcaa cccgggcaat gtcggcttcg gcaagaagaa ggacctacag
    15241 ttcgcccagc tgatcgagtt cgcgatccgc taccacaagc cggtgcgcat cggtgccaac
    15301 tggggctcgc tggaccaggc cctggcggca aagctgatgg acgagaacaa cctgcgtgag
    15361 cagccctggg acgccggccg cgtgctgcgc gaggcgctga tccgctcggc gctggattcg
    15421 gcagagcagg cggtggagct cggcctgccg cgcgaccgca tcgtgctgtc ggccaaggtc
    15481 agtggcgtgc aggagctgat cgcggtgtac cgcgacctgg cccagcgctc ggatttcgcc
    15541 ctgcacctgg gcctgaccga ggctggtatc ggcagcaagg gcatcgtcgc ctcgtccgcg
    15601 gcgctgagcg tgctgctgca ggagggcatc ggtgacacca tccgcatctc gctgaccccg
    15661 gaaccgggcc agtcgcgtac gcaggaagtg atcgtcgccc aggagctgct gcagaccacc
    15721 ggccagcgcg ccttcacgcc gctggtcacg gcctgcccgg gctgcggccg caccacctcc
    15781 gagttcttcc aggagctggc caaggtggta cagaaccacg tgcgcgagaa gatgccgctg
    15841 tggaagatcc accacccggg tgcggagaac atgaccctgg cggtgatggg ctgcatcgtc
    15901 aacggaccgg gtgagtcgcg ccatgccaat atcggcatct cgctgcccgg cacgggtgaa
    15961 acgcctgcag cgccggtgtt cgtcgatggc gaaaagaagg tgaccctgcg tggcgacaac
    16021 atcgcccagg aattcgtcgc cctgatcgac gattacgtcg aacacaagta tgtccgaagc
    16081 gccggataag cctgcgatcc tcgctgcacc ggagtccgcc tccggcttcc gccactggat
    16141 ggcgcgcaat gcctggcgcc tggtcctgct gttcggtggc gtgctgctgc cgctggccgg
    16201 cttcgtcgcc ctggctgacg aggtgcacga gtttgaatcg ttccatttcg atgcgccgct
    16261 gctgtggcag atgcatggcc tgcattcgcc gctgctggac cgcttcttcg tgctcatttc
    16321 cagactgggc tacgaatggt tcctgatccc agccgacgtg ctgatcatcg gcgtgctgct
    16381 gggctaccgg cgttggcgcg aggcgacctt cgtggcggtc agcttcgtcg gctcggcgct
    16441 gctgaacatg ggcagcaagc acttcttcca gcgccagcgc cccagcctat gggaatcgat
    16501 cgcgccggaa tcgacgttca gcttccccag cggccatgcg atgggctcga tgaccctggc
    16561 agtgaccctg gtactgctgg cctggaacac ccgctggcgc tggccggtgc tgctgctggc
    16621 accggcattc agcctgctgg tcagcgtgtc ccgggtctac ctgggggtgc attatccctc
    16681 cgatatcctg gccggatggt gtgccgcgct ggtttgggtg gtagggtgct atctggtcat
    16741 gttcagtcgc cggcacccat ggcgacgtca cggctcgccg ccagcgaagg ccagcgaagc
    16801 atcatcacag ggggattgac gtggatggcc cttgagggac gtctacgtga tagatcagtt
    16861 gtttcgttgc agcaggttct gcaagacagg gggcaagcac aacgcgcggt agtgtgatgc
    16921 gcaaggcaga ttgccggggt cgcattccga acgcgcttgc aggggtatcg gcaccctgcc
    16981 tagcttgacc tgcaatggcc gcattcgaag aggtacgtga atgacgattc gagtctacct
    17041 ggtggatgac cacgcgctgg tccgcaccgg gatgaagatg attctgtcgg gggaaaccga
    17101 catcgaggtg gtgggcgaag ccgagaccgg cgaagacgcg ctgcgtgaag tccgccagct
    17161 gctgcccgat gtggtgctgt gtgacctgca tcttccgggt gtgagcggca tggaagtgac
    17221 cgagcgcatc gtgcgcagcc accgcaatac ccgcgtggtg atcgtgtcgg tgctggaaga
    17281 tggcccgctg ccgaagcggc tgctcgaggc tggcgccgcc ggttacatcg gcaagggctg
    17341 cgatgcgcag gagctgttgc gcgcggtgcg tgacgtggcc ggtggccgcc gttacctggg
    17401 caccagcatc gcgcagaatc tggcgctgtc gacggtggaa ggcaacggtt cgccgttcga
    17461 cagcctgtca ccgcgcgagc tggaagtggc actgctgctg acccagggcc tgcgccagga
    17521 agacatcgcg cggcggttga gcctgagcgc gaagacggtg aacacgcaca aggcgcggtt
    17581 gttcgagaag atggggatcc acgacaacat cgcgttggcg cggatggcca gccagtacgg
    17641 gctggtggat ccggcacggc cgctgtaagg gtttcggcca acggctgagc ccctcgcggt
    17701 ggtggtgcgg ttggattgtg gtggttggcc gggcggatgg gttgagcagg ggacgctgca
    17761 agtacgtcct tgtaagctcg gtcgccgcat ccatgcggct cacgcccctg cacaacccat
    17821 ccgcccggcc acggacagtt tccgtgcgcc gccaccgcgg aatgaagatt gaaaagcagg
    17881 agcgggtcgc gcgctttgcg cgctcgtcgc ctggggtcgg atccctttcc cggtgggaaa
    17941 gggctctgac ccttgatgat gccggagccg agcgtgggct cggctctacc cctttgtcgg
    18001 gctcagtggc cgcgcacgcg ctggatgatc ttggcggcgt cggtggcact ggcgcgcacc
    18061 ttgtcccatt cgccgttggc gatccagttg cccggcacca tccacgaacc gccgatgcag
    18121 accacgttct tctgctcgag gtactcggcg gcggtgtttt cggtgatgcc gccggtcggg
    18181 cacagcttga ggtcggcaac cgggccggcc aggcccttga tcatcgccag cccgcccacg
    18241 gccgtggccg ggaacagctt gcacacgcgg aagccgcgcg catacagcga cagcagctcg
    18301 gtcggcgtgg ccgcacccgg caccaccggc agcggcgcag cggccagtgc atcagccagc
    18361 gccggcggcg tacccggggt caccaggaag tccgcgcccg catcgatcga ctgctgcatc
    18421 tgctccacgg tcagcaccgt accggcgccc accaccacgt ccggcagctc gcgcttgagc
    18481 atcgccagcg cttccatcgc cactggcgta cgcagggtca gctcgatcgc cggcaaacca
    18541 ccttccagca gcgccgcgct gaccgcacgc gcctggtcca gcgtatgaat cgtcaccacc
    18601 ggcaggatgc ccgccgcacg caacagctcc gccgccttca cctgatgttg ttcgataccc
    18661 atagctctgc ttctgccttt gctttcgaat ttgattttca gtgatcactt cgcggcgcga
    18721 gggcgccggg aaactgtcct gaggcggcgg gtagccccca ccaggaccgt gagcgccatg
    18781 gatggcgcga ccgagccccc atggatgggt ttacggcgtg tcctggtggg ggctacccgc
    18841 cgcctcaacc aggacactca ccgccaacgc acacccgcaa cgctcttcaa ccctcaggcg
    18901 tctttcgcct catgcggcgc cgccgccgcc gcggcatcgt gccccagctc atactccgcg
    18961 tcgtactccc acggcccacc atcagccgcc gccggcccgc acgaaatcga aatcgcaccc
    19021 tggtcggccg gacccaccac acgacggttg atcgcgaaca ggttgcggcc cagatcatgc
    19081 gcggcaggcg cggtgttcgg cgccagcgga cgtgcagccc attcggctgc gtccaccagc
    19141 acttccagcg tgccggcctc gccatcgagg cggatcatgt cgccctcgcg aaccttggcc
    19201 agcggaccac cccgcgccgc ttccggcgtc acatggatcg ccgcagggat cttgcccgag
    19261 gcgccggaca ggcggccgtc ggtgaccagc gccacgcgcc ggccctggtt ctgcagcagg
    19321 cccagcagcg gcgccagcga atgcagttcc ggcatgccgt tcgcacgcgg gccctggtaa
    19381 cgcaccaccg ccacgaaatg ctcgggcaac aggccgccgg catgcagctt gttcaacacc
    19441 tgcggtgcat cgaccaccac ggccggtgct tcgatcgtgc ggtactgcgg cttcaccgcc
    19501 gacagcttga tcagcgattt gcccaggttg ccgcgcagca ggcgcaggcc accctggtgc
    19561 tcgaacggat tgtcgacgcc acgcaccacc tcttcgtcgg cgctgcgttc cagacccggc
    19621 aggtagacca gcttgccgtc gcgcagctgc ggttcgcgtg cgtagtcggc catgccgcca
    19681 cgcgccacgc tgaccaggtc gccgtgcatc aggccggcct tgatcagttc gccgaacacg
    19741 aaggccgggc cgcctgctgc ggcgaagcgg tttacatcgg cttcgccgtt cgggtagacg
    19801 cgggccagca gcggaatcag ctgtgacagc tcgtcgaagt cgtcccaggt cagcacgatg
    19861 ccggccgcac gcgccaccgc gatccagtgg atggtgtggt tggtcgagcc gccggtcgcc
    19921 atcagcgcaa tgaccgcatt gataatcgcg cgctcgtcga tgatccggcc caacgggcgg
    19981 aagtcctcgc cgagtgccgt gatgtcgagc gctcgctcgg tggcttcacg ggtcagggcg
    20041 tcgcgcaacg gcgtgcctgg attgacgaac gatgcgcccg gcagctgcac gcccatcgct
    20101 tccagcagta cctggttgga attggcagtg ccgtagaagg tgcaggtgcc ggcgccgtgg
    20161 tacgacgcgg actccgcttc cagcagttct tcgcgggtgg cttcgccggc agcatagcgc
    20221 tcgcgcactt cggccttctg cttgttcgga atgcccgggg tcatcgggcc ggccggcacg
    20281 aacaccgccg gcagatggcc gaaggccagc gcaccgatca gcaggcccgg cacgatcttg
    20341 tcgcagacac cgaggtagac ggtggtgtcg aacatatcgt ggctgagccc gatcgcggtg
    20401 gcctgcgcga tcacatcgcg cgagaacagt gacagttcca tgccgccgcg gccctgggtg
    20461 acgccgtcgc acatcgccgg cacgccgccg gccacctgtg cggtggcgcc cagctcgcgg
    20521 gcgatctcgc ggatctgctc gggataggtc tcgaacggct ggtgcgcaga caacatgtcg
    20581 ttgtaggcgg tgatgatgcc gaggttcggc gtcacgccac cgcgcaggcg gctcttgtcg
    20641 gtgccgccgc aggcggcgaa cccgtgggcg aggttgccgc agctcaggcg gctgcggaac
    20701 gggccttcac gcagcgaggc gtcgatcgcg gccaggtagg cggcacgcga ggcggcgctg
    20761 cggcggataa cacgctgagt gatggcttgc agttgcggat ggaggctcat tggctaccgg
    20821 cgttcgtggt ggcgagaggc aagcggcggc acggtgccgc cgccaacatc aatcagccca
    20881 gtggacgcgc aggcgcgcgc cgtccaggtt gatcgcattg aggatcgggt actgctgggc
    20941 atcgttgctg tccagcgcct ggcgcagcac ctgcagcttc tgcttgccgc gcagcagcag
    21001 caggcgctgg cggcactggc gcaggccatg cggggtcagg gtgatgcgca gcggccactg
    21061 gttggcaccc gggcagccgg tggcgtccag cgcggcatag ggcagggtgc tttccagtgc
    21121 acgggccagg tccttcgagc cggggaacag cgaggcggtg tggccgtcgt tgcccatgcc
    21181 cagcgccacc aggctcggcg gttggctgtg ctgcgcctgc aggttggcgg tgtacacgca
    21241 ttccggaagc ggcttgccga tgcgcaccag cggatcgaaa tgcgcacctt cggcgcgctt
    21301 gaggagattc tcgcgcacca gccaggcatt gctgtcgcga tcctgcggcg acagccagcg
    21361 ctcatcggcc aggctcactt ccacgcggtc ccagtgcacg tccagttcgg ccagcgcctg
    21421 gtacaccggt gccggcgtgg tgccgccgga caacaggatg cgggcgcggc ccacttcgtt
    21481 gatgtcgtgg ttgagggtct gcgccatctc ggcggccacc gcctcgatcc agccatcggc
    21541 atcgccgtgc tggatgaact cgatgcggtc gtcgtggaag gtggtggggc tcatgcggca
    21601 actccaggtg cgtcacgttc ggcgtcggcg gcataggcgg cggcgcccag cagtccggcg
    21661 tgggggtgca tcacggccaa cgagggcacc cgcgccatga tcgaggagaa gcggcccttg
    21721 tgttcgaagc gctggcggaa cccggagtgc tgcagcgaat cgagcatctt cggggtcagc
    21781 ccgccggtca ggaacacgcc gtcccacgcg ccctgggtca gcaccaggtc gcctgcgatg
    21841 gcgccgaaca cggcgcagaa cacatcgacg gtgcgcatcg cctgcgggtc accgtgcagg
    21901 gcgcgggccg tcacgtccac cggctgcagt tggcccggat cgatgccggc catctcgcat
    21961 acggcgcgat ggatgttgac caggccaggg ccgcagatca ggcgctcgtt ggagacgcgg
    22021 ccgaactgtt cggacaggat ctccaggatg cggatctcct ccggggttcc cggcgggaag
    22081 ctgacatggc cgccttcggt ttccagcggg tagcagcggc cgtggcgcag gatcaggcca
    22141 ccgacaccca ggcccgtacc cggcccgatc accgcgtagt tgcgcggctg gccgggtttg
    22201 cccggcaccc aggcggcacc gccgacctgg accacgtcat cgggctgcag cagcgaaatc
    22261 gccatcgcct gtgcggcgaa gtcgttgatc aggtgcagtt cgttgaagcc gagcatggcg
    22321 gcggtgcggc tgcgcgagat cacccacggg tggttggtga tgcgcgcttc gtcaccgtcg
    22381 acgcgaccgg ccaccgcgaa cacgccgcgg ctggccgtgg cgccgatctg ttccagatgg
    22441 tggcgcgcgg catcacccag cgacgggaac tccgccactg cgtactcgcg gatgctgtcc
    22501 ttctgcagcg gtgcgtcctg cgaggtgtcg gccagggcga agcgggcgtt ggtaccgccg
    22561 atgtcggcga ccagcaccgg ctgcgagctg gcactcatgc cgacgctccg ctgtccggcg
    22621 cgtccacgcc ctgcggcagg aactcgcccg cgttggccgg gccccactgg ccggcggggt
    22681 agggttccag cggcagcttg gcatccttcc aggcgtcggc gacgctgtcg atccacgccc
    22741 aggcggcgcg cacttcgtca tcgcgcacga acagcgtgtg gttgccgttg aaggcatcca
    22801 ggaacaggcg ttcgtaggcg atgcggcggt gcaggccagt cggcaccgac agttccagtt
    22861 ccagcggatg cagctccagc gcgccccatt ccgggccg
//
