LOCUS       NZ_CP067993            10876 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain DHHJ chromosome, complete
            genome.
ACCESSION   NZ_CP067993
VERSION     NZ_CP067993.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4682909)
  AUTHORS   Cao,Z.-J.
  TITLE     Genome Characterization of a novel Stenotrophomonas isolate with
            high keratinase activity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4682909)
  AUTHORS   Cao,Z.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2021) Bioengineering Department, Donghua
            University, North People Road, Shanghai 201620, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 336.0x
            Sequencing Technology             :: PacBio RSII; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016659185.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:56:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,314
            CDSs (total)                      :: 4,222
            Genes (coding)                    :: 4,196
            CDSs (with protein)               :: 4,196
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 10 of 26
            Pseudo Genes (incomplete)         :: 16 of 26
            Pseudo Genes (internal stop)      :: 0 of 26
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:47:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1420131
            Orig. end                         :: 1431007
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067993.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang-Jun Cao.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10876
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10876
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5876](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5876)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(2028..2042)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    2222..2242
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.71"
                     /tool="antismash"
     gene            complement(2884..3468)
                     /gene="rnt"
                     /locus_tag="JJL50_RS06500"
                     /old_locus_tag="JJL50_06500"
     CDS             complement(2884..3468)
                     /GO_function="GO:0016896 - RNA exonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /GO_process="GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rnt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408782.1"
                     /locus_tag="JJL50_RS06500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06500"
                     /product="ribonuclease T"
                     /protein_id="WP_164080706.1"
                     /transl_table=11
                     /translation="MSQRFRGFLPVVVDVETGGFDSQRNALLEIAAVPIEMDENGLLYP
                     GQTASAHVVPAEGLEIDPKSLEVTGIILDHPFRLAKEEKAALDHIFSPVRAAMKKYGCQ
                     RAILVGHNAHFDLGFVNAAVARTGHKRNPFHPFSVFDTVTLAGIAYGQTVLARAATAAG
                     LGWDANEAHSAVYDTEQTARLFCTIANAWPR"
     gene            complement(3704..4225)
                     /locus_tag="JJL50_RS06505"
                     /old_locus_tag="JJL50_06505"
     CDS             complement(3704..4225)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014036543.1"
                     /locus_tag="JJL50_RS06505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06505"
                     /product="DoxX family protein"
                     /protein_id="WP_049463604.1"
                     /transl_table=11
                     /translation="MNLPTLAATRGQLDRLAPWLAPLGLRLLLAWEYFESGREKLHGQN
                     WFADLQDAFPFPFDQLPATLNWQLATWFELIGAACLLVGFGTRFAAASLLVLTVVATYA
                     VHWPMEWNSLADLAMGYAITDQGFGNFKLPVLFMAMLLPLIFTGAGRLSVDAWLARWSP
                     SATPARPAVR"
     gene            complement(4253..5008)
                     /locus_tag="JJL50_RS06510"
                     /old_locus_tag="JJL50_06510"
     CDS             complement(4253..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412767.1"
                     /locus_tag="JJL50_RS06510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06510"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_125895760.1"
                     /transl_table=11
                     /translation="MTDARGTLRAQQHAFTAHLRDPQGVPPPAGLEARRVTVYQRLLFN
                     NLLGLLSNGFPVCVRLLGEPAWSDLVRHYFATHRCQTPLFTELAAEFVQWLQAQPQLPH
                     PALAELAHYEWVETALYQLQAEPLPAPGDIDPLQVPLQRSPLAWPLLYQWPVHRLGAED
                     APMQPPAEPTGLLVRREADGEVRFAVLSPLAVYLLSSVGERPGLDGHAYLRQLAAANGL
                     AEEALAGPGAALLQQFLQAGVIGPLTVPG"
     gene            complement(5001..5876)
                     /locus_tag="JJL50_RS06515"
                     /old_locus_tag="JJL50_06515"
     CDS             complement(5001..5876)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014036545.1"
                     /locus_tag="JJL50_RS06515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06515"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_049421603.1"
                     /sec_met_domain="DUF692 (E-value: 1.2e-116, bitscore:
                     386.6, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASTDVRASLVHPRSPLRAAAAGLGLRRALLQDLRDAPAGDFDFL
                     ECAPENWIHVGGPAGDALAELAQRHPLSCHGLSLSLGGSAPLDTQLLEQVGQFLEKHRV
                     PLYSEHLSYCSDDGHLYDLLPIPFTDEAVRHTAARIAHVQDLLGRRIAVENVSYYLAPE
                     PAMDELAFTNAVLAEADCDLLLDVNNVYVNACNHGYDADTFIAGLPAERVVCLHVAGHL
                     DEAPDLKIDTHGSAVIDPVWELLARTYARIGPRPTLLERDFNFPPYAELQGELQTIRRL
                     QATHGGTAHD"
     gene            complement(5863..6222)
                     /locus_tag="JJL50_RS06520"
                     /old_locus_tag="JJL50_06520"
     CDS             complement(5863..6222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646537.1"
                     /locus_tag="JJL50_RS06520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06520"
                     /product="hypothetical protein"
                     /protein_id="WP_049421602.1"
                     /transl_table=11
                     /translation="MSSSNKTLSLLTATALAAGLGMTASASALSMSDLAQGYLVAGQAA
                     KAADTKHAEGKCGADGKTAEGKCGGDKGKAAEGKCGEGKCGADKGKAAGAAAAKTGDKK
                     SAEGKCGEGKCGGKH"
     misc_feature    complement(6309..6323)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.25"
                     /tool="antismash"
     misc_feature    complement(6315..6330)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    6368..6380
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(6428..7135)
                     /gene="phoU"
                     /locus_tag="JJL50_RS06525"
                     /old_locus_tag="JJL50_06525"
     CDS             complement(6428..7135)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="phoU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265615.1"
                     /locus_tag="JJL50_RS06525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06525"
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="WP_014036547.1"
                     /transl_table=11
                     /translation="MNLPNDHIVKSYDEEQQRLVAEIVRMGEMAVAQLEAAMDVIEKRD
                     ENAAHRIIANDEAIDALEQQISHDVMRLALRGPMARDLREILAGLRIPADIERIGDYAA
                     NVAKRSIALGKVPPLPQIQGLRALGRLAAQQVRRAIAAYRDNDADAALELREDDARLDA
                     QYTALFRELLTYMMEDPRNITPCTHLLFMAKNLERVGDHATNIAENVWFLVHGEQPLPP
                     REKRDETSSTGQP"
     misc_feature    7107..7122
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.64"
                     /tool="antismash"
     gene            complement(7201..8031)
                     /gene="pstB"
                     /locus_tag="JJL50_RS06530"
                     /old_locus_tag="JJL50_06530"
     CDS             complement(7201..8031)
                     /EC_number="7.3.2.1"
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pstB"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019237787.1"
                     /locus_tag="JJL50_RS06530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06530"
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="WP_005408788.1"
                     /transl_table=11
                     /translation="MNDLSNAVPMQRIAVPSSHESLHTPSPVKLAARGLDFYYDKFHAL
                     KGINLEIPEKRVTALIGPSGCGKSTLLRIFNRIYALYPKLEARGEVLLDGENILSPKYP
                     MNRLRSKVGMVFQKPVPFPMTIFENVAYGIRHHEKLSKADMADRVEQALRQGALWDEVK
                     DKLGQSALGLSGGQQQRLCIARAVALRPSVLLLDEPTSALDPISTSRIEQLVEELKHEY
                     TIVIVTHNMQQAARVSDYTAFMYLGDLIEHDRTEVIFSQPSQRQTEDYITGRFG"
     gene            complement(8051..8914)
                     /gene="pstA"
                     /locus_tag="JJL50_RS06535"
                     /old_locus_tag="JJL50_06535"
     CDS             complement(8051..8914)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pstA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412770.1"
                     /locus_tag="JJL50_RS06535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06535"
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="WP_032127902.1"
                     /transl_table=11
                     /translation="MSTTADSLYLRRRIGNVVAITASCATALFGLFFLGWILFTLASKG
                     LAGINWDLFTKMTPPPMQEGGLANAFFGSAVMCALAIGIGTPLGVLAGTWLAEYGNARK
                     AGTVVRFVNDILLSAPSIVLGLFVYTLYVMQTGGNFSAFAGALSLAFIVLPVVVRTTDE
                     MLRLVPSQMREAALSLGIPQWKVIVQVLYRSASAGIITGILLALARISGETAPLLFTAF
                     GNQYWNNNIFQPMASVPVVMNQFAGSPYESWQVLAWAGALVLTVFVLLVSLAARGILLR
                     NRISHD"
     gene            complement(8914..9882)
                     /gene="pstC"
                     /locus_tag="JJL50_RS06540"
                     /old_locus_tag="JJL50_06540"
     CDS             complement(8914..9882)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pstC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008572163.1"
                     /locus_tag="JJL50_RS06540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJL50_06540"
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="WP_201118578.1"
                     /transl_table=11
                     /translation="MNAIAQPVAAPSTRDARDARNDKLFRWVLVGTVIFVLIALACAAL
                     SMLWGGRHALQMQGLSFFFSADWNPVENKFGALAPIYGTLVTAVIAMVIAVPVSFGIAF
                     FLTEVAPRWLRGPVGTAIELLAGIPSIIYGMWGLFVLVPVMTEYVTPFLNETLGEWPII
                     GPLFQGPPLGIGMLTAGFVLAIMVIPFISSVMREVFLTVPTRLKESAYALGSTKWEVSW
                     DIVLPYTRSAVIGGIFLGLGRALGETMAVAFVIGNSVRLSPSLLEPGTTIAALIANDFG
                     EATETYRSALLLLGFVLFIVTFVVLAIARLMLMRLSRKEGN"
     misc_feature    complement(10350..10363)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    10600..10614
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
ORIGIN
        1 ggacagccag ggccgcctgt ggctgctgta tgaaggcaag ggcatcggct atctgacgcc
       61 ggacaccggc atcgtctacc aggctccggc cgccgacctg ccgatggcga tgagcttcac
      121 caagctggtg gtcgatgcgc aggaccgggt ctgggccggc acgttggatg gactggtgct
      181 gcgcgacaac gacggggtgc tcaagcgggc gcccgcggcg tgggggctgg gcgccggcag
      241 tggcctgtcg tggccgtacc gcgctccgga tggcgcgctg tggatcgtcg ccggcgagcg
      301 cctgtaccgg gtggaggatg atcagctggt gctgatgcac cgcctgccgg ggcagctgca
      361 cctgacctcg atgctgcagg atcgccatgg cgacctgtgg ctgggcaccg agaaccaggg
      421 cctgctgcgg atctcagcgc atggcctgga gcgcctgccg gcgggcctga acctgccggg
      481 tgggcgcgtg gtcagcctgc gcgaggatgc cgagggcagc atctgggtgg gtgccaacgg
      541 tggcctgtac cgcctgcgcg aaacactgtt cagcagctac accgagcgcg atggcctcag
      601 tggcgactat gtgcgcaccg tgttcgagga ccgcgaacgc cagctgtggg tcggcagtgc
      661 cagcggcctc gacctgcaga ctgctgatgg ccgcttccgc gcgatgccgc tgcacaaccg
      721 cggcggcaag gcaccttcgg tgctcagcct ggcgcagggt ccggacggtg acctgtgggt
      781 cggaacgttc ggtgatggcg tctaccgtct tggccccgat ggccggctgc ggcacaacta
      841 tgccgccgcc gatggcatgc cgggcggcaa catccgcgcg atcagcgtgg acccgcaggg
      901 cgtggtctgg gccggcaccc agaagggcgt ggtccgcatc gacggcgacc gcgtgcaggt
      961 atcaagcgtt gcgggcatgc ccagcggcct gatcaccgcg cttgagcacg atcaccaggg
     1021 caacctgtgg atcggcacca tcgagggcat ccgcgtactg cgcggcgacc acgtgcagtc
     1081 gatcgacctc gcgccgatgg gcggtggccg cagcgtgttc ggcttccatc agctgggtga
     1141 cgcgatgtgg atcagcagcg atcgcggcct gtaccgctgg cgcaacggca cgcttgcacg
     1201 ggtggggctg gagcagggca tgccggtgga tgcggtgttc caactggtgc cggatcgcct
     1261 tggcaacgtg tggatcagca gcaaccgcgg cgtgctgcgc accgacatgg gcaccctcaa
     1321 cgccgtggcc gatggccgcg caccccgggt ggtggtggag cgctacaacg agattgacgg
     1381 catggccaat gcgcaggcca acggcagctc cgggccatcg gcgatcctgc gccaggacgg
     1441 cacgttctgg gtggtcaccg ccggaggcct gagcaccgtc gatccgcaac gcctgcagcg
     1501 tttccgcgag cgtctttcac cgcctgcagc gattgaaagc gtgcaggtgg atggcgcacc
     1561 ggtgcattgg gaaggccccg accgcaacta cattcccggc ggccgccgct tggcggtgag
     1621 ttatgtcggc ctgagctacc tgatgtctga tcggatccgc taccgcacgc ggttggacgg
     1681 cctggatacg gggtgggtcg aacgcggccc gcagcgcagc gtggagttcg tcggcctgcc
     1741 gccgggcgac tacaccctgc acgtggccgc tgcccatccg agcggcagct ggggccagca
     1801 ggaagcggta tggagcttca ccgtggagcc gttctggtgg cagcgacgca gcgtgcaggt
     1861 gctgggtgga ctgctgctgc tggccgggct ggtggcgctg taccgcctgc tgctgcagca
     1921 gctgaaggcc agcaacctgc gcctggcgcg gcgcgtggac gaggcgacct tcgacctgca
     1981 ggccaagacc gtgcacctgc aggcgctgaa ccaggaaaag accgaactgg ccgagcgcct
     2041 cgcacgccag gccgaggcat tcgaacggca ggcccgcgag gatgcactga ctggcctggc
     2101 caaccgccgt gctttcgatg aaacgctggc gcgtgacttc gcgcgttcgc agcgcagcgg
     2161 tcatccgctg tgcctggtgg tgctggatat cgaccacttc aaggacgtca acgaccgcca
     2221 cagccacagc atcggcgatg ccgtgctggt gcaggtggcg cggttgatcg ccgccgccag
     2281 ccgcgattcg gacctgccgg cgcggactgg cggcgaagag ttcgcgctgc tgctcaacga
     2341 cacccgcctg gaggaagccg cacagctgtg cgcgcgcctg cgcggcctgt ttcacgacca
     2401 tcccgactgg gccggggtgg acggcctgcg cgtgaccttc agcgcgggcc tggtggaact
     2461 ggatgcggac gaccgcaccc cggcactgct gtaccagcgc gccgaccgcg cgttgtaccg
     2521 cgccaagagc gatggccggg atcgaacgag catcggttga ttgcatccac gcatggcgtg
     2581 gatctacggg tgttgccgta ccaacggtcg gcacccagca gagaggtgac tcaccacagc
     2641 ggtgatcggc agcccgcaac gagcgcagcg acccgctgtt gcttccgctt ttctgatctt
     2701 tccgtggcgc tcgctggaaa ctgtccgtgg ccgggcgggt gggctgcgca ggggcgtgag
     2761 ccgcatggat gcggcgaccg agcttacagg gacgtacttg cagcgtcccc tgcgcagtcc
     2821 acccgcccgg ccctaccagg aatcgctgtc agcccgccac gaggggctcc gccgttggcc
     2881 gcttcaccgc ggccaggcgt tggcgatcgt gcagaacaag cgcgcggtct gttcggtgtc
     2941 atacaccgcg ctatgcgcct cgttggcatc ccagcccagc ccggcggcgg tggccgcacg
     3001 cgccagcacg gtctgcccgt aggcgatgcc ggccagggtc accgtgtcga acacgctgaa
     3061 gggatggaac ggattgcgct tgtggccggt gcgcgccacg gcggcattga caaagccgag
     3121 gtcgaaatgc gcgttgtggc cgaccaggat cgcgcgctgg cagccgtact tcttcatggc
     3181 cgcgcgtacc gggctgaaga tgtggtccag cgccgccttc tcttccttgg ccagccggaa
     3241 cgggtggtcg aggatgatgc cggtcacttc cagcgacttc gggtcgatct ccaggccctc
     3301 ggccggcacc acgtgggcac tggcggtctg gccggggtag agcaggccgt tctcgtccat
     3361 ctcgatcggc acggcggcga tttccagcag cgcgttgcgc tggctgtcga agccgccggt
     3421 ttccacgtcc accaccaccg gcaggaagcc gcggaagcgt tgtgacatcg cgcgctgcgc
     3481 ctgggggact gcggaatcgg gagcggcggc aggtgcgggg gtggggtcag tcatgcgtga
     3541 attctagcag agcgaccctg agcgcccggc cagccttcgg tgcatgcgtt ccctgcgcgg
     3601 gcgtgtgtcg accaaggtcg acacctaccg ggacaccgcg cgctcaggat tccggtaggt
     3661 gccaaccttg gttggcacac ggtgcgccga ccaggtttgg cgattaccgg actgctggcc
     3721 gtgcaggcgt ggccgaggga gaccaccgcg ccaaccacgc atccacgctc agcctgccgg
     3781 cgccggtgaa gatcagcggc agcagcatcg ccatgaacag tactggcagc ttgaagttgc
     3841 cgaagccctg gtcagtgatc gcgtagccca tggccaggtc ggccagcgag ttccactcca
     3901 tcggccaatg caccgcatag gtggccacta cggtcagcac cagcaggctg gcggcggcaa
     3961 accgggtgcc gaagccaacc agtaggcagg ccgcgccaat cagctcgaac caggtggcaa
     4021 gctgccagtt cagggtggcc ggcagctggt cgaacgggaa cgggaaagcg tcctgcaggt
     4081 cggcgaacca gttctggccg tgcagctttt cgcggccgga ttcgaagtat tcccaggcca
     4141 gcagcaggcg caggccgagc ggggccaacc agggggcgag acggtccagc tggccacgcg
     4201 tggcggccag ggtcggaagg ttcatcggtg gttctccgtg ggggaaaggg cgtcagccag
     4261 ggactgtgag cgggccgatc acgccggcct gcaggaactg ctgcagcagc gcggcaccgg
     4321 gcccggccag cgcctcctca gccaggccgt tcgcagcggc caattgccgc agataggcat
     4381 gtccatcgag gccgggtcgt tcgccgacgc tggacagcag gtataccgcc agcgggctga
     4441 gcacggcgaa gcgcacttcg ccatcggcct cgcggcggac cagcaggccg gtcggttccg
     4501 ccggcggctg cattggcgca tcctcggcac cgagtcgatg caccggccac tggtacagca
     4561 gcggccacgc caggggtgag cgctgcagcg gtacctgcag cggatcgatg tcgccaggtg
     4621 ccggcagcgg ctcggcctgc aactggtaca gggcggtctc cacccactcg taatgagcga
     4681 gttcggccaa cgccgggtgc ggcagctgcg gctgtgcctg cagccactgc acgaattcgg
     4741 cggccagttc ggtgaacagc ggtgtctggc agcggtgggt ggcgaagtag tggcgcacca
     4801 ggtcgctcca ggcgggctcg ccgagcaggc gcacgcagac cgggaagccg ttgctcaaca
     4861 ggccgagcag attgttgaac agcagccgtt ggtacaccgt gacccggcgt gcctccagcc
     4921 cagccggcgg tggcacgccc tgcggatcgc gcagatgggc agtgaacgca tgctgctgcg
     4981 cgcgcagggt gccacgagcg tcagtcatgt gcagtccccc cgtgcgtcgc ctgcaggcgg
     5041 cggatggtct gcagttcgcc ctgcagctcg gcgtatgggg ggaagttgaa atcgcgctcg
     5101 agcagggtgg gacgtgggcc gatgcgcgcg taggtacgcg ccagcagctc ccagaccggg
     5161 tcgatcaccg cgctgccatg ggtatcgatc ttcaggtccg gcgcctcgtc caggtgcccg
     5221 gccacgtgca ggcagacgac gcgctctgcg ggcagtccgg caatgaaagt gtcggcgtcg
     5281 tagccatggt tgcaggcatt gacgtagacg ttgttgacgt ccagcagcag atcgcagtcg
     5341 gcttcggcaa gcaccgcgtt ggtgaaggcc agttcgtcca tcgccggttc cggtgccagg
     5401 taataggaca cgttctccac tgcaatgcgg cggcccagca gatcctgcac gtgagcgatg
     5461 cgtgccgcag tgtggcgcac cgcttcgtcg gtgaacggaa tcggcagcag gtcgtacagg
     5521 tgaccgtcgt cgctgcagta gctcaggtgc tcgctgtaca gcggcacgcg gtgcttttcc
     5581 aggaactggc cgacctgttc cagcagctgc gtatccagcg gcgcgctgcc gcccagcgac
     5641 aacgacaggc cgtggcagct caacggatgg cgctgcgcca gttcggccag tgcatccccg
     5701 gcgggaccac cgacatggat ccagttttcc ggcgcacatt cgaggaagtc gaagtcacct
     5761 gccggggcgt cacgcaggtc ctgtagcagc gcccggcgca ggcccaaccc ggcggccgcc
     5821 gcacgaagcg gcgaccgcgg gtggacgagg ctggcgcgga cgtcagtgct tgccaccgca
     5881 cttgccttcg ccgcacttgc cttcagccga cttcttgtcg cctgtcttgg cagcggctgc
     5941 accagcagcc ttgcccttgt cggcaccgca cttgccttcg ccacacttgc cttcggcagc
     6001 cttgcccttg tcaccgccgc acttgccttc agcggtcttg ccgtcggcgc cgcacttgcc
     6061 ttcggcgtgc ttggtatcgg cagcctttgc cgcctggcca gccaccaggt agccctgggc
     6121 caggtcgctc atgctcaggg ccgaggcact ggcggtcatg cccaggccgg cggccagggc
     6181 cgtagcggtc agcagggaca gggtcttgtt ggaactgctc atcggtctta ctcctaggtg
     6241 gtgggcaggc gcccggggtg aatcgatggt gcagcgatcc tactcaacga atcctcgcca
     6301 agaactcaaa ttttcgtgag atttgttaca gagggggaga ccggtggccg gaacgcccaa
     6361 aacaaaaggg ccgctgtcac caggacagcg gccaccgtgg agtcgactcc ggtgttgcag
     6421 tgcagcgtca gggctggccg gtgctggagg tctcgtcgcg cttttcacgc ggcggcagcg
     6481 gctgctctcc gtgcaccagg aaccacacgt tctcggcgat gttggtggcg tggtcgccca
     6541 cgcgctccag gttcttggcc atgaacagca ggtgcgtgca cggagtgatg ttgcgcgggt
     6601 cttccatcat gtaggtcagc agctcgcgga acagcgcggt gtactgcgcg tccaggcggg
     6661 cgtcgtcctc acgcagttcc agtgcggcgt cggcgtcgtt gtcgcggtag gcggcaatgg
     6721 cacggcggac ctgctgcgcg gccaggcggc ccagcgcacg caggccctgg atctgcggca
     6781 gtggcggcac cttgcccagc gcgatcgagc gcttggcgac gttggcggca tagtcaccga
     6841 tacgctcgat gtcggccgga atgcgcaagc cggccaggat ttcgcgcagg tcgcgcgcca
     6901 tcgggccacg cagcgccagc cgcatcacgt cgtggctgat ctgctgttcc agcgcatcga
     6961 tcgcttcgtc gttggcgatg atgcgatggg cagcgttctc gtcgcgcttc tcgatcacgt
     7021 ccatcgccgc ttcgagctgg gcgacggcca tttcacccat gcgcacgatt tcggccacca
     7081 ggcgctgctg ctcttcgtcg tagctcttga cgatgtggtc gttgggaaga ttcatggtct
     7141 gcaatccggg tagagccagg ccatgcctgg ctgggacatg tggcgaaggg acggcgtcga
     7201 tcagccgaag cggccggtga tgtagtcctc ggtctgccgc tgcgacggct gcgagaagat
     7261 cacttcggtg cggtcgtgct cgatcaggtc gcccaggtac atgaaggcgg tgtagtcgga
     7321 cacgcgggcg gcctgctgca tgttgtgggt gacgatcacg atggtgtact cgtgcttgag
     7381 ctcttccacc agctgctcga tgcggctggt cgagatcggg tccagcgccg aggtcggttc
     7441 gtccagcagc agcaccgacg ggcgcagggc cacggcacgg gcgatgcaca ggcgctgctg
     7501 ctggccgccg gacaggccca gtgcgctctg ccccagcttg tccttcactt cgtcccacag
     7561 cgcgccctgg cgcagcgcct gctcgacgcg gtcggccatg tcggccttgc tcagcttctc
     7621 gtggtggcgg atgccgtagg ccacgttctc gaagatggtc atcgggaacg gcaccggctt
     7681 ctggaacacc atgccgacct tgctgcgcag gcggttcatc gggtacttcg gcgacaggat
     7741 gttctcgccg tccagcagca cctcaccgcg cgcttccagc ttcgggtaca gcgcgtagat
     7801 gcggttgaag atgcgcagca gggtcgactt gccgcaaccg gagggaccga tcagcgcggt
     7861 cacgcgcttt tccgggatct ccaggttgat gcccttcagg gcatggaact tgtcgtagta
     7921 gaagtccagt ccacgcgcag ccagcttcac cggcgacggc gtgtgcaggc tctcgtgcga
     7981 ggacggcacg gcgatgcgct gcatcggcac ggcgttggaa aggtcgttca tggcgttatc
     8041 cacggaaagg tcagtcatgg gagatacggt tgcgcagcag gatgccgcgg gcggcaaggc
     8101 tgaccagcaa cacgaagaca gtcagcacca gggcaccggc ccaggccagc acctgccagg
     8161 attcatacgg gctgccggcg aactggttca tcaccaccgg caccgaggcc atcggctgga
     8221 agatgttgtt gttccagtac tggttgccga aggcagtgaa cagcagcggt gcggtctcgc
     8281 cggaaatgcg cgccagggcc agcaggatgc cggtgatgat gccggccgac gcactgcggt
     8341 acagcacctg cacgatcacc ttccactgcg ggatgcccag cgacagcgca gcctcacgca
     8401 tctgcgaggg caccaggcgc agcatctcgt cggtggtgcg caccaccacc ggcagcacga
     8461 tgaaggccag cgacagcgca ccggcgaacg ccgagaagtt gccgccggtc tgcatcacgt
     8521 acagcgtgta gacgaacagg ccaagcacga tggacggggc cgacagcagg atgtcgttga
     8581 cgaagcggac cacggtgccg gccttgcggg cgttgccgta ctcggccagc caggtgccgg
     8641 ccagcacgcc cagcggggtg ccgatgccga tcgccagcgc acacatcacc gcactgccga
     8701 agaaggcgtt ggcgagaccg ccttcctgca tcggcggcgg cgtcatcttg gtgaacagat
     8761 cccagttgat gccggccagg cccttcgagg ccagggtgaa caggatccag ccgaggaaga
     8821 acaggccgaa cagggcggtg gcacaggagg cggtgatcgc aacgacgttg ccgatgcgac
     8881 ggcgcaggta cagcgaatca gcggtggtgg acatcagttg ccctccttgc gggacaggcg
     8941 catcagcatc aggcgggcga tggccagcac cacgaaggtg acgatgaaga ggacgaagcc
     9001 gagcagcagc agggccgagc ggtaggtttc agtggcttcg ccgaaatcgt tggcgatcag
     9061 cgcggcgatg gtggtgcccg gttccagcag cgacggcgac aggcgcacgc tgttgccgat
     9121 cacgaaggcc acggccatgg tctcgcccag ggcgcgaccg aggccgagga agatgccacc
     9181 gatcaccgcc gagcgggtgt agggcagcac gatgtcccag ctcacttccc acttggtgga
     9241 gcccagcgcg tacgccgact ccttcaggcg ggtgggtacg gtcaggaaca cttcgcgcat
     9301 caccgaggag atgaacggaa tgaccatgat ggccagcacg aaaccggcgg tgagcatgcc
     9361 gatgcccagc ggcgggccct ggaacagcgg gccgatgatc ggccattcgc ccagggtctc
     9421 gttgaggaac ggggtgacgt actcggtcat caccggcacc agcacgaaca ggccccacat
     9481 gccgtagatg atcgagggaa tgcccgccag cagttcgatg gcggtaccga ccgggccacg
     9541 cagccagcgc ggcgcgactt cggtgaggaa gaaggcgata ccgaagctga ccggcacggc
     9601 gatgaccatc gcgatgacgg cggtgaccag ggtgccgtag atcggggcga gcgcaccgaa
     9661 cttgttttcg accggattcc agtcggcgga gaagaagaag ctcaggccct gcatctgcag
     9721 ggcatggcgg ccgccccaca gcatggacag cgcggcgcag gccagggcga tcaggacgaa
     9781 gatgacggtg ccgaccagca cccatcggaa cagtttgtcg ttgcgggcat cacgcgcatc
     9841 acgcgtggac ggggcggcta caggctgggc gatggcattc atggggacgg cagggccagg
     9901 aaggggcggg gcggcacggc gtggaagaag cggtgcccgc gcggggcggg caccgccgtg
     9961 tccatcactt caggtcggtc gcccagtagg cctcgatctg cttgaccagt tcggccggca
    10021 gcggcacgta gtgcagctcg ttggcctggg cctggccgtt ctcgaaggcc cacttgaaga
    10081 aggccagggt gtcctggttg cgcttggcgt ccttcggctg cttctgcatc agcatgaagt
    10141 tggtggcggt gatcggccac gcctgctcgc ccggggcgtt ggtgatgacc aggttgaagt
    10201 ccttggcgct ggcccagtcg gcgctggcag ctgcagcggc gaaggtttcc gcgctcggct
    10261 cgacccagtt gccggccgcg ttctgcatgg cggtgtacgg catgccgttc tgcagtgcgt
    10321 aggccagttc gacgtagccg atcgagccct tgatctgctt cacgtacgaa gcaacgcctt
    10381 cattgccctt gccaccgacg ccgtccggcc actgcaccga ggtgccttcg ccgaccttgc
    10441 tcttccattc cgggctgacc ttggacaggt agttggagaa gttgaaggtg gtgcccgaac
    10501 cgtccgaacg gtggaccagg gtgatcttgc cgtccggtag cttcacgccc gggttggcgg
    10561 cgacgatggc cgggtcgttc caggtcttga ccttgcccag gaagatgtcg gccagcaggg
    10621 cgccgctcag gcgcagcttg ccggcttcca ggccttcaat gttgaccacc ggcaccacgc
    10681 cgccgatggc cgacgggaac tgggccaggc cagcctgggc cagctcttcg ctgctcagcg
    10741 gcttgtcgga ggaaccgaag tcgacggtgc cggccttgat ctgggcgatg ccgccgccgg
    10801 agccgatcga ctggtagttg atcttggccc cggtgctggc gttgtagtca gccgaccact
    10861 tggacaccag cgggaa
//
