LOCUS       NZ_CP067230            22622 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Paracoccus sp. MC1862 plasmid unnamed5, complete sequence.
ACCESSION   NZ_CP067230
VERSION     NZ_CP067230.1
KEYWORDS    RefSeq.
SOURCE      Paracoccus sp. MC1862
  ORGANISM  Paracoccus sp. MC1862
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Paracoccaceae; Paracoccus.
REFERENCE   1  (bases 1 to 41778)
  AUTHORS   Mingchao,X.
  TITLE     Paracoccus sp.MC1862
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 41778)
  AUTHORS   Mingchao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) Chinese Center for Disease Control and
            Prevention, National Institute for Communicable Disease Control and
            Prevention, Changping, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. HGAP 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 282.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016617715.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:33:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,607
            CDSs (total)                      :: 3,551
            Genes (coding)                    :: 3,394
            CDSs (with protein)               :: 3,394
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 65 of 157
            Pseudo Genes (incomplete)         :: 116 of 157
            Pseudo Genes (internal stop)      :: 29 of 157
            Pseudo Genes (multiple problems)  :: 44 of 157
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:42:09
            NOTE :: This is a single region extracted from a cross-origin
            section of a larger, circular record.
            Orig. start                       :: 39117
            Orig. end                         :: 19961
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067230.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     misc_feature    complement(28..47)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.61"
                     /tool="antismash"
     misc_feature    797..817
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.54"
                     /tool="antismash"
     misc_feature    902..917
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.04"
                     /tool="antismash"
     misc_feature    complement(943..998)
                     /db_xref="RFAM:RF03058"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03058"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sul1 is cis-regulatory element that is thought to
                     sense ions involved in sulfur or methionine metabolism;
                     They are found in Alphaproteobacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
     gene            1454..2434
                     /locus_tag="JGR78_RS17850"
                     /old_locus_tag="JGR78_17850"
     CDS             1454..2434
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018238006.1"
                     /locus_tag="JGR78_RS17850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17850"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_182793158.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-28,
                     bitscore: 91.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADIPASVSVVITARDAAATIADAVRTALDEPETAEVIVVDDAS
                     RDATAEVARAAAQGDGRLRVIRCEVNIGPAAARNRALAVATGEFVAVLDADDFILPGRF
                     ARLLAVPGWDMVADNILFVAESASPADLPPLPAIAPALIDIDLAGFVRANRSGRGANRH
                     EWGFLKPIMRRDFLQAQGLRYDETLRLGEDYDLYVRMLQKGARFRVSTETGYAARWRAQ
                     SLSSRHRTADLAALLTAVRAHLAAPGLDRAAREALRAHLAEQRRRFLLRDFLDRRAKAG
                     RAGAVLSALRRPATLVPIARGILADKLAARRPATPARIGRLLIEG"
     region          1..22622
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22622
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22622
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12622](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     misc_feature    2658..2675
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.21"
                     /tool="antismash"
     proto_core      10001..12622
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    2669..2686
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.21"
                     /tool="antismash"
     misc_feature    complement(2671..2686)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     misc_feature    complement(2703..2716)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.64"
                     /tool="antismash"
     misc_feature    complement(2707..2720)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.23"
                     /tool="antismash"
     misc_feature    complement(2758..2773)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            2890..3918
                     /locus_tag="JGR78_RS17670"
                     /old_locus_tag="JGR78_17670"
     CDS             2890..3918
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008667376.1"
                     /locus_tag="JGR78_RS17670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17670"
                     /product="replication initiator protein A"
                     /protein_id="WP_234450994.1"
                     /transl_table=11
                     /translation="MNSPLLPDRHPQRDFFVCDIFNAAPKADVGPMEHPIFSLSTKPDL
                     RPRHYEHNGLSVEIKPSSDGMATVHDRDILIFCISQLIRALNDGREVSQIVRFQAADLL
                     RATNRMTTGRGYDLLKAAMERLAGTRISTNITTGGEEIFETFGLIESARIVRQTREGRM
                     QEIEIKLSDWVFNAIRAQEVLTISRDYFRLRRPLERRLYELARKHCGNQKEWMVGLDLL
                     QKKCGSSSSSFEFRRLVANVIREDIAHSHMPDYSVRFSDDGDRVVFRNRGTAPLAEAEI
                     FEGFLDPEAYEEARAAAPGWDVRHLEGEWRRWCAAEEIEPKHPARHFVRFCQSWHEKRG
                     KP"
     gene            4056..5192
                     /locus_tag="JGR78_RS17675"
                     /old_locus_tag="JGR78_17675"
     CDS             4056..5192
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.5"
                     /locus_tag="JGR78_RS17675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17675"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_182805442.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 3.4e-31, bitscore:
                     99.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFTEQLIASVRGDSGAEIAVLTAAACPASPQAAGPEPTGPRRPP
                     DPDRLFDIARLNKMLGQLPVSPAALPPGCAALAPRLLQARLRTAAMNRAAMAVTAEVSR
                     AFAGAGLRHAVLKGPFQQMAVHGDPFRRPSGDIDLFVTPRDRRRAAALLQGLDFAPMEQ
                     EQALWWVPFLGEQHFRRERDGAVVDLHHRLQQAGLPDWRGAAGVLDRAVTQAHGGDAIP
                     VLSPADGCLLMAVTLAKALLAREPCGWAAAELAHWLARLDPADRRMLDGIAAASGQERT
                     LALGITLARACHDHSALAGAGAAPLRGLPAGPALLRDLVFQPWQRRAEAPRRRQMLRML
                     TEGRPHVLAAEAARAALSLRVQAALARREQRGARTSAR"
     gene            complement(5181..6314)
                     /locus_tag="JGR78_RS17680"
                     /old_locus_tag="JGR78_17680"
     CDS             complement(5181..6314)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.5"
                     /locus_tag="JGR78_RS17680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17680"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_182793155.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.3e-32,
                     bitscore: 102.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPAPASATRPVVSVVMANFRGAPHLAAAMRAVLAQSEQRLELIL
                     ADDASDDDSVAIARGIAGTDDRVRVIASPRNQGPAATRNGALDAARGDWIAVVDSDDLI
                     HPERLSRLIAAAEAAGADLVADDLVHFGAPAEQGRTLLQPLALAAPMWLAAPAYLRANG
                     GDPALPSFGYLKPVIRRAVLGGRRYDPRLRIGEDYDLVLRLLIDGARFLLLPDPLYAYR
                     RHPGSISHRLSVGTVAAMLQAHRALPPLSDPEARAAAAAVDRQLRRSLRYERLVAEIKA
                     RRWSRALPRLADPATVARLAGSLRDRRRRKAALQAQDHAEGAVSPDPVAALPLPGQPWD
                     SPPAPAAARIAAGGTPPPGAPGWALWLAGATAGGSAG"
     gene            6444..7241
                     /locus_tag="JGR78_RS17685"
                     /old_locus_tag="JGR78_17685"
     CDS             6444..7241
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012925.5"
                     /locus_tag="JGR78_RS17685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17685"
                     /product="family 16 glycosylhydrolase"
                     /protein_id="WP_182793154.1"
                     /transl_table=11
                     /translation="MRHSLALIALLTAAGQPVLAQSSDQPTDKAHPETAGFREDFTGAL
                     DRDRWYVSDGWTNGDWQDCHWSEKAVTVQDGMLVLSHIPASGDGGPPLCGEVQTKARFH
                     YGTVEARIRTPRQSGMNASVFTYAGPVHDSPHSEIDIEILTREPGEMTVNTYVEGEPVN
                     GATVPTAPPFDQEFHNVAFRWEADGITWYLDGQEVHRTEPGSPLPDHPQKIYMSFWSTT
                     VLTEWMGEQTPRDEPLGYEIDWVAYTPLEAACLFEGSITCARP"
     gene            7306..8610
                     /locus_tag="JGR78_RS17690"
                     /old_locus_tag="JGR78_17690"
     CDS             7306..8610
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016800.5"
                     /locus_tag="JGR78_RS17690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17690"
                     /product="O-antigen ligase"
                     /protein_id="WP_234450997.1"
                     /sec_met_domain="Wzy_C (E-value: 6.4e-11, bitscore: 33.8,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTGAARRHGHGHRRATPAGPGLTISYSPLALAGFLALFGLCFIV
                     PLGSKGALLFLAAGMAVALSRPGATLAALRQEWMLVLLALWCLMSFAWSDYPSLTIRYG
                     IQFCLTVVIALVLSYRLAPMTFVKVLFVASSLAGLASLLSGRTREDGMGYLGIYASKNA
                     LANASALLVILALAVLIDRRLSWRWRLPALASLLVGALLLVMGKSSGALVSTIGVVGVF
                     GVIVLLQRLTPYARLVLVALALVLAAAAGVLLSFVVPELSQWFLNTTGKDVTLTGRTDL
                     WAVAFHEIAERPVLGVGFQAFWVHGQPLAEQLWAMFGIGGRSGFNFHNTLISNAVEIGL
                     IGAALQAVIFFGGLAASLSWAIRSPSAASVFFALFMVRQFMLMWIEAAYFYQFELSSVI
                     TIAAVCYGRGFRRTQRPPVQAAIARRGRPGLPAIT"
     gene            complement(8684..9409)
                     /locus_tag="JGR78_RS17695"
                     /old_locus_tag="JGR78_17695"
     CDS             complement(8684..9409)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012321516.1"
                     /locus_tag="JGR78_RS17695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17695"
                     /product="sugar transferase"
                     /protein_id="WP_234450995.1"
                     /sec_met_domain="Bac_transf (E-value: 7.6e-66, bitscore:
                     212.3, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQMLRAHDLVADTDSPKLVAPHVQSPAARPLQIPRTVPVGGAAKR
                     ALDIFLVILAIPLLLPLILGLVIILRIKDPGPLLYGHRRIGFGGREFRCWKFRTMVVDG
                     DAVLERHFRSNPAAEAVWKEQRKLVDDPRVTPLGAVLRKLSLDELPQLLNVLKGEMSLV
                     GPRPIVQAELDHYGASARHYLAARPGLTGLWQISGRSDTTYAERVRLDRFYVTNWNLWQ
                     DLRIVFMTIPAVAMSRGAH"
     gene            9727..9864
                     /locus_tag="JGR78_RS17700"
                     /old_locus_tag="JGR78_17700"
     CDS             9727..9864
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGR78_17700"
                     /product="hypothetical protein"
                     /protein_id="WP_182793185.1"
                     /transl_table=11
                     /translation="MVKTYSRPVLRVQGQLEAMTHGNSRGSALDNTFQAGTPVSQLTFS
                     "
     gene            10001..10261
                     /locus_tag="JGR78_RS17705"
                     /old_locus_tag="JGR78_17705"
     CDS             10001..10261
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="JGR78_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17705"
                     /product="PqqD family protein"
                     /protein_id="WP_182793184.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.6e-26,
                     bitscore: 83.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.2e-19, bitscore: 61.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYLASPECVSCAVEDGIAILDLKSNTYFSLDPVGARIWDRMTAP
                     SSLEDLTAAIAAEYEIAPGECRRDIADLLDDMLKHGLIRAV"
     aSDomain        10007..10255
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JGR78_RS17705_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.20E-26"
                     /identifier="RREFam002.1"
                     /label="JGR78_RS17705"
                     /locus_tag="JGR78_RS17705"
                     /protein_end="85"
                     /protein_start="2"
                     /score="83.5"
                     /tool="antismash"
                     /translation="YLASPECVSCAVEDGIAILDLKSNTYFSLDPVGARIWDRMTAPSS
                     LEDLTAAIAAEYEIAPGECRRDIADLLDDMLKHGLIRA"
     gene            10263..10727
                     /locus_tag="JGR78_RS17710"
                     /old_locus_tag="JGR78_17710"
     CDS             10263..10727
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011840871.1"
                     /locus_tag="JGR78_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17710"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_182805472.1"
                     /sec_met_domain="PF13471 (E-value: 2.1e-20, bitscore: 64.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVLRRIRRLRRRDAVLLWQALGAVLLVRGYLGRGAHHDLRRMIE
                     AHGLTLPAADPGAPRAELAEIAWSVRAVARLVPGASCLTQASAGQILLARRGHATTIRL
                     SVPAQTATPGILAPHAWLMAGDTIVLGGTPEDYNRHRILHDFTLPGAGPA"
     gene            10724..12622
                     /locus_tag="JGR78_RS17715"
                     /old_locus_tag="JGR78_17715"
     CDS             10724..12622
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="JGR78_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17715"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_182805470.1"
                     /sec_met_domain="GATase_7 (E-value: 8.5e-20, bitscore:
                     62.2, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 6.2e-35, bitscore:
                     112.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRFAAMLGHGPDHDPAAWRIAADLTRRTGEIPGYRGAEGLHLWQ
                     AGRTGSPATVRTLGPLTLAGDLALTDLPELRGALAAHPGSDPADLVLAAWRRWGTDAPD
                     RLNGAFAFVLWDARTRRLTAVRDRFGIQPLAYALTPRRAVFASDLSTVLAGLDAVPGID
                     RAWVAGFLAGQPLDATATAWGDVSRLPPGHLMTLDPDGTAALRRWYRLERTAPPDPRDA
                     DAALHAALAHATVQACADGPTATMLSGGLDSSTLALLSVGPDAPAPCRRPALSLRYRDP
                     AMDEGRHIHEVLRRSGRELAPVFLPGEAEDDTLFDIDAQLDWQDQPVFAPGLERNHRLY
                     RAAREQGCAAVLDGHGGDEVIGGSFRDIALIAGEGRWPLALALAVRHARFTGEPVSQAL
                     ATLLAIRGRRGFGRLGRWALKDAGPDPRDWRALVDPDLARETRLVERARTGQAPTPEDR
                     HLPEGVRLHAAMLTGPLAPAAFETMGRAAQAEGVAPRYPFYDHRVVELCVWQPEPAKVA
                     GGQPRALLRRAMRGILPESVRMRGDKTDFIAGFWGALRRDPQGRIAALRADPGPLRGWV
                     DTGILRADAERLARAPEPDLETAFRLWRSLWLAAWLERPALSLSSRAPGPTLASVR"
     gene            12619..13557
                     /locus_tag="JGR78_RS17720"
                     /old_locus_tag="JGR78_17720"
     CDS             12619..13557
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS17720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGR78_17720"
                     /product="serine kinase"
                     /protein_id="WP_182793181.1"
                     /transl_table=11
                     /translation="MTAVPALSAPPLQAHAYAAYGLCVVSDVILPELAPGMPGRPADLR
                     ISEAPQPAIPRSPLPDCRFGPEGTWFWWPEVGAFSVSADGSRIGIERRPGISDDLLAFP
                     LLGPVLFEALRRNGLFVLHASAVVHRGRGIAFLADKGVGKSTTATGFLRNGARLLADDL
                     VAIDGEGRMLPGFGQVKLSEGAARMLPPGATVRGPVHDAIDKARAMLDPAHLAGTPVPA
                     ARLYLLERARRGQPSEVLRLPPSEALAAVLRFSYAVRFGPALLNGAAAAQHFRAAAQVA
                     LRCPPRRLLLAEGLDRAPDIRAAIDRDLGDD"
     gene            13550..15382
                     /locus_tag="JGR78_RS17725"
                     /old_locus_tag="JGR78_17725"
     CDS             13550..15382
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="JGR78_RS17725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17725"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_182793180.1"
                     /transl_table=11
                     /translation="MTDASPPLTAPVPTEEARARSRGAAGQLASLWRALRHLEGRRLWI
                     GLALLVLGTLSEGAAIVTFLPVLQLVGAGGTSIDMSGLDFPGAGLLPAMVPLGALLLVI
                     VGLTALQAIFNRSKAVYLSDLIHDFTNHHRTALFREVALARWSHVARIPRTRIEHALTG
                     EIERLYLAAFLVLSILQNLVGLALYFVLSLAISAPMTLLSYGFGVVALVLMRPFRRLAR
                     HYGDRLQARREGQLAAVSEFVGSLKMARSMNLEDRYLGLFSAILGQTKADARQFIRQSS
                     IGTGLFQFAVVSGAALFIWVALAWAQLDVARIVILLLLFMRTAPRFMGIQGSVQQLLVD
                     LPAWGAISRLRDDLQAERDPAMAGHDPAPAPRRDIRLDRVSWRFPGESREAVSDCSLTL
                     RAGELTVLVGPSGAGKSTLADIVMGLLEPQKGTVLVDGKALRPGQFRGWRDRTGYVAQE
                     PFMINGSIRDNMAIAAAGPVDDDRIFRALDLASAGFVRDLPAGLDTMMGDRGTLLSGGE
                     RQRIAVARALLREPDVLVLDEATSALDWENEEALIRAIGGLRGRMTILAITHRPALIRV
                     ADAVFVMESGRVTASERPREQGPQAESYLGRMTS"
     gene            complement(15358..15585)
                     /locus_tag="JGR78_RS17730"
                     /old_locus_tag="JGR78_17730"
     CDS             complement(15358..15585)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGR78_17730"
                     /product="hypothetical protein"
                     /protein_id="WP_182805468.1"
                     /transl_table=11
                     /translation="MFVIHYLITAVAVISGLLAWAIPAGYSAWQIAGLAFVAVLALQAA
                     ILAFVVFAAARRDRACNARKRPDQLVILPR"
     gene            complement(15658..18111)
                     /locus_tag="JGR78_RS17735"
                     /old_locus_tag="JGR78_17735"
     CDS             complement(15658..18111)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216: exopolysaccharide biosynthesis domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025179.5"
                     /locus_tag="JGR78_RS17735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17735"
                     /product="GNVR domain-containing protein"
                     /protein_id="WP_182793178.1"
                     /transl_table=11
                     /translation="MPRDLKPFELASPYGASQAAQVQTIDLRRVMVAMRRQRRTILLPA
                     VLLGGLGLAYAASKPATYEAFSSLLLDSNVNRSVQQAGGIDTAVLPSDRIENARVVLES
                     EKLAYDVLDRTGLQANPSFMNPPESGFSNLVGRVMGTLLAPIAWVQDRITALTSSTPVI
                     DPAALPSATSFGDPSVAPIDPERRLAAMRLQGGMEIYRVGQSSAVAVSFSSHDPFIAAE
                     AANAYADAYVQDILVTNAESVGQTNAWMRGRLDELQTQAQAAANAAERFAAANGLVEFS
                     SGGLLTEQALNELNSGLTVALTDAARAQAVLDTYDRAVAGGVEGLTDSSSSLAIGGDMS
                     EELRSRLDNYNDVRARLQRLLASSGPNHPQVAGLRQTLASTAERLFVELEAMRAEAQSA
                     LDVARARVEALQQSVNQASQRNSAQAANFVRLRALQEEAATLSALYQQTLTRSQEIEQQ
                     QSFPVSNVRILSYAQVPAVPSGPAVLRTTLAATLLGLFGGLALAALREGRERMLRTASD
                     VTDRSALRFLGHLPVLPRVRRLRAGKVALPESRPVPRISAAPQAAKRGEMLPVLSKPKP
                     PVINVPVPVLHFPDSVYAETLRHVRLATEASGSPMPVTGVTSFHPYEGRSLVAFNLAGQ
                     LGVGLQSVLLIDTDSRGRGLSRMLGLDQRPGLTDAVAGRGDWESMLVGIANTNVNVLPC
                     GSTAGGASDDLMTGKLLGQIVEDACHEFSRVIVDVPPLYPVAQGRAILHELPRFLIVGE
                     WGRTPRSMVETVLAEEPELEANCLGVVYDRVNLRKLRSFLMPEAMENYLGRSKSRLTLR
                     RRGEP"
     gene            complement(18111..19100)
                     /locus_tag="JGR78_RS17740"
                     /old_locus_tag="JGR78_17740"
     CDS             complement(18111..19100)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009564402.1"
                     /locus_tag="JGR78_RS17740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17740"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_182805466.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.1e-14,
                     bitscore: 45.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNPVLRDAVLVGICTFRRPELAATLDSLARLDPCGLPVSIAIAD
                     NDCTPSARDRVQEVAATHPLPITYLHAPEANISIARNALLDHAHATGARFLVYLDDDER
                     AEPAWLARLVAAWKAGQQSGAGTGAVLGPVQAHYPAGAPGWMDRARAHDTLPVFGKDGA
                     VLSGYSGNILIDLADPAARDLRFDLSRGRSGGEDSAFFADFLAAGGRIGFAPDAVVHED
                     VPPDRARLAWLLRRRYRMGQTHASLIARGRSRGGRLGAAGVAAAKAMACGGLALLGAAR
                     PAWRNRQIMRAALHVGAAAHLGGAPQIEIYGTAPGRTDPAPRHAPKEN"
     gene            complement(19097..20098)
                     /locus_tag="JGR78_RS17745"
                     /old_locus_tag="JGR78_17745"
     CDS             complement(19097..20098)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008833916.1"
                     /locus_tag="JGR78_RS17745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17745"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_182793176.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.9e-17,
                     bitscore: 52.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPMFPDPKVLIVIPTLNEAAHIAGVLDFAVAFAERADGLVVVADG
                     GSRDATCDIVRRRAADHRRIRLLHNPRRLQAAAVNLAVERFGQGAEWLLRLDAHSTYPA
                     DYGDVLLAEARRTGAASVVVSMHAEGQGFLQRIIADAQNSPFGNGGSAHRLAGGDAWVD
                     HGHHALMQVAAFREVGGYDESFSHNEDAELDRRLSAAGRRIWLTSRTRLTYFPRQSIRA
                     LMRQYYNFGRGRARNLIKHNARPAARQALAAMLAPAAALVPLAPFSVVFVLPSVLWVLA
                     CLAGGVVISMQTKRPDGLLAGLVAGTMHMAWSAGFWRQWLSRRETVPARAAT"
     gene            complement(20106..21281)
                     /locus_tag="JGR78_RS17750"
                     /old_locus_tag="JGR78_17750"
     CDS             complement(20106..21281)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002719714.1"
                     /locus_tag="JGR78_RS17750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_17750"
                     /product="glycosyltransferase"
                     /protein_id="WP_182793175.1"
                     /transl_table=11
                     /translation="MTYLAHDLDDPSIWRRVEMLRRGGASVRVAGFRRGDGPLAEPAIV
                     LGRTVNARMGQRVRAILAAWPGLARRVPPPDGHGEPEVVLARNLEMLALGARLVRARKG
                     RARLVYELLDIHGMMLGQGAVARSLRRVEAGLMRRAALVVLSSPAFAARYLRPHGQPDL
                     PALLVENKPFARPDAGPRQAGPAPGGLEEGGPLVIGWFGMLRDDWSLKTLDRLTRSRPG
                     RFRVVLRGRPALDVMPDFHAIIGANPDMEFRGPYDWPGDLPAIYGGVDVAWLIDRYQAG
                     QNSDWLLPNRLYEGCLNGAVPVALEGTEVARRVAGWDCGVVVADPGPEAVAGALSALDP
                     VGLARLRGAVAAIPRDRLEMDRAECRRLTAAICGASPVPAARTAPVPAITG"
ORIGIN
        1 cagcgcgaac aggatcgcca agagcggcca ggggcccaag gccccgaggg caggagggat
       61 atgcgcccgc ccccggcaga gcagcacccc cagcgggaag gaaaagcaca gccgcgccag
      121 gccggcatca aggctggtcc agcggacgcc gccgtcgatg gtgccggcgg tcaccgcatt
      181 gaagcacagc accgccccgg caccgccgac catggcgatc aggacgcgcg tcgacagcca
      241 gcggtgcgcc agaccgaagg ccaggctggc cagcacctcc agaaacagcg accaggccgg
      301 ggggttcagc gggaacaggt gcggcggctc ctgcatggag ggccagggga tgaacagggc
      361 ccccagcacc agcgccagaa ccaccgcgtc gggcggcagg cggtagtcgc cggccagcgc
      421 ccccggcagc accagcagcg ccgcgatccc cagcccggcc cagtgcagcg gggtcagccg
      481 gaccatcctg agccaaagga accgccccac gggcaggccg tccctgagct tgccgtcata
      541 cgcgtgggcc acgacgaagc cgctgaggac gaagaagaaa tccaccgcca gataggcgct
      601 gcgcgccagc cccggccaca aaaggaaact gctggtgtgc agcagcagca cggcgagcgc
      661 ggccaccccg cgcagcgcgt ccagcgtctc gtagtagcgc gcggcagggc gcgggggcgg
      721 gacatcgcgg agcggctccg gtgccacaag gctgtgcgcc ccggcctttg cgcccttgct
      781 gtcgaagttg atcgtcatgt cgccaccttg aagatcaagg ttcacgccgg gtcatgctgc
      841 aggcgccgag gcttccggtt ccagagccat ccagtgaaat cacgggaggt ccgtcagcct
      901 gctgaccgat tgttcgagct tgcggcggaa ctgatcgttg caagttgtcc ggcggatcgg
      961 cggccggaag agccacccgg aatttcaccg ggtcctgacg gatgaatcat ggttaacgcg
     1021 cacccggcca ggtagcaacc ccggcactcc gccccggtct gcccggcgcg gtcccctgtc
     1081 ccacccgaag gcggcatcgg catcggccgc ggcgacagtg ccgggaagac gccgggcggg
     1141 cggtgaaacc ggtggttcgg catggggttg cgcgaatggc ggccggtatg cgcagcccag
     1201 ccggtccgtc ggcaaacaag gatcacacgg atgccgccgc gttgcccgct tccttccgtg
     1261 gtaatcttcc cgtgaacggc aggctcaagc cggctgcggc ggttcgggcc gagcttctgg
     1321 gggcaaccgg ggcgagggca gcaggcagcg ccgtggccgg tgccccatcc ggcgccgggc
     1381 accgccccgg atcacccgga cccggccgcc ggcaggctgg actttcgtcc cgacgcttgc
     1441 cacggaaaga cccatgagcg ccgacatccc tgcctccgtt tccgttgtca tcaccgcccg
     1501 cgacgccgcc gcgaccatcg ccgacgcggt gcgcacggcc ctggacgagc cggaaaccgc
     1561 cgaggtgatc gtggtcgacg acgcctcgcg cgacgccaca gccgaggtcg cccgcgcggc
     1621 cgcccagggg gacgggcggc tgcgggtgat ccgctgcgag gtgaacatcg gccccgccgc
     1681 cgcccgcaac cgggcgctgg cggtggcaac gggcgagttc gtggcggtgc tggacgccga
     1741 cgacttcatc ctgcccggcc gcttcgcccg gctgctggcg gtgccgggct gggacatggt
     1801 ggccgacaac atcctgttcg tggccgaaag cgcatccccc gccgacctgc cgccgctgcc
     1861 cgccatcgcg ccggcgctga tcgacatcga ccttgcgggc ttcgtgcgcg ccaaccgttc
     1921 gggccgcggc gcgaaccggc atgaatgggg cttcctcaag ccgatcatgc gacgcgattt
     1981 cctccaggcg caggggctgc gctacgacga gacgctgcgg ctcggcgagg actacgacct
     2041 ttacgtgcgg atgcttcaga agggcgcacg cttccgcgtc agcaccgaga ccggctatgc
     2101 cgcccgctgg cgggcacagt cgctgagctc gcgccaccgc acggccgatc tggcggccct
     2161 gctgacggcc gtccgcgcgc atctggcggc acccggcctc gacagggcag cgcgcgaggc
     2221 gctgcgggcg cacctggccg aacagcgccg gcggttcctg ctgcgcgact tcctcgaccg
     2281 ccgcgccaag gcgggccggg caggggcggt gctgtccgcc ctgcgccgcc ccgccactct
     2341 ggtcccgatc gcgcgcggca tcctcgcgga caagctggcg gcccggcgtc ccgccacccc
     2401 ggcgcggatc gggcggctgc tgatcgaggg ctgaaccttc ctccaggccg gaaggccatg
     2461 gacaggcgct gccggaagcc ccgcagggaa ccgtggcatg ccccccgatc aggctgcccg
     2521 tcggcgaagg gcgggaccat gcaagaggcg ccttcacgca tctccgccag ccctgcttcc
     2581 cgtcccggca ccgccggccc cacttccaat tccccagcca tcttcgtgct tgacgcgact
     2641 tatccacagg gggccctgtg ttaaataggt gttaaatagg tgttaagcgc agacaaaagg
     2701 ctttttttct actacttatc aaagctttga aatgtctgcg tctgtgtgaa gtgtcgtttc
     2761 ttcatgtgta aagtggtgat tcgtcatgtg tgaagtgtcg tttctccccg cttcatgggt
     2821 gaagtgtcgt taaccttgat tcatgtgtga agtgtcgtta tgggtgaagt gtcgtttccc
     2881 cgaggccata tgaacagccc gcttcttccc gaccgtcatc cgcaacgtga tttcttcgtc
     2941 tgcgacatct tcaacgccgc ccccaaggcc gatgtcgggc cgatggagca tccgatcttc
     3001 tcgctctcga ccaagcccga cctgcgcccc cgccattacg agcacaacgg gctgtcggtc
     3061 gagatcaagc cctcctccga cggcatggcc acggtccacg accgcgacat cctgatcttc
     3121 tgcatcagcc agctcatccg ggcgctgaac gacgggcgcg aggtcagcca gatcgtccgc
     3181 ttccaggccg cggaccttct gcgggcgacc aaccggatga ccacggggcg gggctacgac
     3241 ctgctgaagg cggccatgga gcggctggcc ggcacccgca tctcgaccaa catcaccacc
     3301 ggcggcgagg aaatcttcga aaccttcggc ctgatcgaaa gcgcccgcat cgtgcgccag
     3361 acccgcgagg gccggatgca ggagatcgag atcaagctgt cggactgggt cttcaacgcc
     3421 atccgcgcgc aggaggtgct gaccatcagc cgcgactatt tccggctgcg ccggccgctg
     3481 gaacggcggc tttacgaact ggcgcgcaag cattgcggca accagaagga atggatggtc
     3541 gggctggacc tgctgcagaa gaaatgcggc tcgtcctcgt ccagcttcga gttccggcgg
     3601 ctggtggcca acgtgatccg cgaggacatc gcccattcgc acatgccgga ctattcggtg
     3661 cgcttctcgg acgacgggga cagggtggtc ttccgcaacc gcggcaccgc gcccctggcc
     3721 gaggccgaga tcttcgaggg cttcctggac cccgaggcct acgaggaggc ccgcgccgcc
     3781 gcccccggct gggacgtgcg ccacctggaa ggggaatggc gccgctggtg cgcggccgag
     3841 gagatcgagc cgaagcaccc cgcccgccat ttcgtccgct tctgccagtc ctggcacgag
     3901 aagcgcggca agccctgaag ggcggcaaaa ccctccctgt gcgggcgccg accccgcttg
     3961 ccccggcccg gaccttcggg tgaaatgccg cgaagggcag ggccaaggcc ttgcggtgcc
     4021 gcatcgggcg ggcatcaggc aggcggaagg cgcggatggc attcaccgaa cagttgatcg
     4081 catcggtccg gggcgactcg ggggccgaga tcgccgtgct gaccgctgcg gcgtgcccgg
     4141 ccagcccaca ggccgcaggt cccgaaccga cggggccgag gcgcccgccc gatcccgacc
     4201 ggctgttcga catcgcccgg ctgaacaaga tgctgggcca gttgccggtc agtcccgccg
     4261 cgctgccccc cggctgcgcc gcgctggcgc cccggcttct gcaggcgcgg ctgcggaccg
     4321 ccgccatgaa ccgcgcggcc atggcggtca cggccgaggt ttcccgggcc ttcgcgggcg
     4381 cggggctgcg ccatgccgtg ctgaaggggc cgttccagca gatggccgtc catggcgatc
     4441 ctttccgccg cccctcgggc gacatcgacc tgttcgtgac cccgcgcgac cgcaggcggg
     4501 cggcagcgct tctacaaggg ctggacttcg cccccatgga gcaggagcag gcgctgtggt
     4561 gggtcccctt cctgggcgag cagcatttcc gccgcgaacg tgacggcgcg gtggtcgacc
     4621 tgcatcaccg gctgcagcag gcgggcctgc cggactggcg gggcgcggcg ggcgtcctcg
     4681 accgcgccgt gacgcaggcc catggcgggg acgccatccc ggtcctgtcg cccgccgacg
     4741 gctgcctgct gatggcggtg acgctggcca aggcgctgct ggcgcgcgag ccctgcggct
     4801 gggccgcggc cgagctggcg cactggctgg cccggctgga cccggccgac cggcggatgc
     4861 tggacgggat cgccgccgca agcgggcagg agcggacgct ggccctgggg atcacgctgg
     4921 cccgcgcctg ccacgaccat tcggcgctgg caggcgcggg tgcggccccg ctgcgcgggc
     4981 tgccagccgg ccccgccctg ctgcgcgacc tggtgttcca gccctggcag cgccgggccg
     5041 aggcgccgcg ccggcggcag atgctgcgga tgctgaccga gggccgcccc catgtgctgg
     5101 cggccgaggc agcccgcgcc gccctgtccc tgcgcgtgca ggcggcgctg gcgcggcgag
     5161 agcagcgggg cgcgcggacc tcagcccgct gaccccccgg ccgtcgcgcc tgccagccag
     5221 agcgcccagc cgggcgcgcc gggcgggggc gtgccgccag ccgcgatccg cgccgcagcg
     5281 ggggcagggg ggctgtccca aggctggccg ggcagcggca gggcggcaac gggatcaggg
     5341 gaaacggcgc cctctgcgtg gtcctgcgcc tgcagggcgg ccttgcggcg gcggcgatcg
     5401 cgcaggcttc cggccagccg ggcgaccgtc gccggatcgg ccagccgggg cagggcgcgg
     5461 ctccagcgcc ttgccttgat ctccgcgacc agccgttcat agcgcagcga ccggcgaagc
     5521 tggcggtcca ccgccgccgc ggccgcccgc gcctcggggt cggaaagcgg cggcagggcg
     5581 cggtgggcct gcagcatcgc cgcgaccgtc ccgaccgaca gccggtgcga gatggaaccg
     5641 ggatgccggc gataggcgta aagcgggtcg ggcagcagca ggaagcgggc gccgtcgatc
     5701 agcagccgca gcaccagatc ataatcctcg ccgatcctga gccgcgggtc gtagcggcgg
     5761 ccccccaaca ccgcacgccg gatcaccggc ttgagatagc cgaaggaggg cagggccgga
     5821 tcgcccccat tggcgcgcag gtaagccggc gccgcgagcc acatcggcgc ggccagcgca
     5881 agcggctgca gcagggtgcg gccctgctcg gccggggcgc cgaaatgcac gaggtcatcg
     5941 gccaccagat ccgcccccgc ggcttccgcc gccgcgatca ggcgcgaaag ccgttccggg
     6001 tggatcaggt cgtcgctgtc caccacggcg atccagtcgc cccgcgccgc gtccagcgcc
     6061 ccgttgcggg tggcggcggg gccctggttg cggggactcg cgatcacccg cacccggtcg
     6121 tcggttccgg cgatcccgcg cgcgatcgcc acgctgtcgt cgtccgaggc gtcgtcggcg
     6181 aggatcagct ccagccgctg ctcggactgt gccaggaccg cgcgcatggc ggccgccaga
     6241 tgcggggcgc cgcggaaatt ggccatgacc accgagacca cgggccgcgt ggcggaagca
     6301 ggggcagggg tcacggctgc gttcccgccg gattgcacga catgtgaacg cctttccgtt
     6361 gaccgacccg cgccgggctt ccataagccg cgggagtcaa ggcggcaacc gcccgccatc
     6421 ccccgcggcc gagaaggttc gagatgcgcc attcccttgc cctgatcgcc ctgctgaccg
     6481 ccgcaggcca gccggtcctg gcgcagtcct ccgatcagcc gaccgacaag gcccatcccg
     6541 agaccgccgg cttccgcgag gatttcaccg gcgcgctgga ccgcgaccgc tggtatgtct
     6601 cggacggctg gaccaacggc gactggcagg actgccactg gtctgaaaag gccgtgacgg
     6661 tgcaggacgg gatgctggtg ctgtcccaca tccccgcctc cggggacggc ggcccgcccc
     6721 tctgcggcga ggtccagaca aaggccaggt tccactacgg cacggtcgag gcgcgcatcc
     6781 gcaccccccg gcagtcgggc atgaacgcct cggtcttcac ctatgccggc ccggtccacg
     6841 acagcccgca cagcgagatc gacatcgaga tcctgacccg cgagccgggc gagatgacgg
     6901 tgaacaccta tgtcgagggc gagccggtga acggcgcgac cgtgcccacc gcgcccccct
     6961 tcgaccagga gttccacaat gtcgcctttc gctgggaagc ggacggcatc acctggtatc
     7021 tggacgggca ggaggtccac cgcaccgaac ccggcagccc gctgcccgac cacccccaga
     7081 agatctacat gtccttctgg agcacgaccg tgctgaccga atggatgggc gagcagaccc
     7141 cccgcgacga accgctcggc tacgagatcg actgggtggc ctatacgccg ctggaggccg
     7201 cctgcctgtt cgagggatcg atcacatgcg cccgcccgtg accgccgcgg gtcgcgcgca
     7261 tcttccggtc gcggccattg cggcacggat ggcaggttga tcgccatggg aaccggcgcg
     7321 gcacggcggc atgggcacgg acacaggcgg gcgacgcccg ccgggccggg gctgaccatc
     7381 agctattcgc ccttggcgct ggcggggttc ctggcgcttt tcggcctttg cttcatcgtg
     7441 ccgctggggt ccaagggggc gctgctgttc ctggccgccg gcatggcggt ggcgctcagc
     7501 cggccgggcg cgacgctggc ggcgctgcgg caggaatgga tgctggttct gctggcgctc
     7561 tggtgcctga tgtcctttgc ctggtcggac tatccgtccc tgacgatccg ctacggcatc
     7621 cagttctgcc tgaccgtggt gatcgcgctg gtcctcagct accggctggc gcccatgacc
     7681 tttgtcaagg tcctgttcgt ggcaagctcg cttgcggggc tggccagcct tctgtcgggc
     7741 cgcacccgcg aggacgggat gggatacctc ggcatctatg ccagcaagaa cgcgctggcg
     7801 aatgcaagcg cgcttcttgt catcctggcg ctggcggtgc tgatcgaccg gcggctgtca
     7861 tggcgctggc gtctgccggc gctggccagc ctgctggtcg gggcgctgct gctggtgatg
     7921 gggaagtcat cgggcgcgct ggtcagcacc atcggcgtgg tcggggtctt cggcgtcatc
     7981 gtgctgctgc agcgcctgac cccctatgcg cggctggtct tggtggctct tgccctggtg
     8041 ctggccgcgg cggcgggggt gctgctgtca ttcgtggtgc ccgaactgtc gcaatggttc
     8101 ctgaacacca ccggaaagga cgtcacgctg acgggccgga cggacctgtg ggccgtggct
     8161 ttccacgaga tcgccgaacg gccggtcctg ggcgtggggt tccaggcctt ctgggtccat
     8221 ggccagccgc tggctgaaca actctgggcg atgttcggga tcggcggccg cagcgggttc
     8281 aacttccaca acaccctgat ctcgaacgcg gtggaaatcg gcctgatcgg ggcggcgctg
     8341 caggcggtga tcttcttcgg gggccttgcg gcgtcgctgt cctgggcgat ccgcagcccc
     8401 tcggccgcct cggtcttctt tgcgctcttc atggtgcggc agttcatgct gatgtggatc
     8461 gaggccgcct atttctatca gttcgagctg tcctcggtga tcaccatcgc cgccgtctgc
     8521 tacgggcgcg gcttccgcag gacacagcgc cccccggtgc aggcggccat cgcccgcagg
     8581 gggaggccgg gtctgccggc catcacctga gaacccctcg gaacggcaac ggggcgccct
     8641 ttcacaaggg cgccccgcgg cggtcttccg gcaagggcgt ggctcagtgg gcgccgcgtg
     8701 acatcgccac cgccggaatg gtcatgaaga cgatccgaag atcctgccac aggttccagt
     8761 tggtgacgta gaaccggtcc aagcgcaccc gttcggcata ggtggtgtcg ctgcggccgc
     8821 tgatctgcca cagtccggtc aggccggggc gggcggccag gtaatgccgg gccgaggcgc
     8881 cgtaatggtc cagttccgcc tgcacgatcg gacgggggcc gaccaggctc atctcgccct
     8941 tcagcacgtt cagaagctgc ggcagctcgt ccaggctaag cttgcgcagc accgcgccga
     9001 ggggggtgac gcggggatcg tcgaccagct tgcgctgttc cttccacacc gcctcggcgg
     9061 cgggattgct gcggaaatgc cgttcaagca ccgcgtcgcc atcgacgacc atggtgcgga
     9121 acttccagca cctgaactcg cgccccccga agccgatgcg gcgatggccg taaagcagcg
     9181 gcccagggtc cttgatcctg agaatgatga ccagcccgag gatcagcggc agcagcagcg
     9241 gaatggcaag aatgacaagg aaaatatcca gggcccgctt tgccgcgccg ccgaccggaa
     9301 ccgtccgcgg gatctgcagc ggccttgcgg cgggggattg cacatgagga gcaacaagct
     9361 tgggcgagtc ggtatcggca acaagatcat gagcacggag catctgcatc tgaacaccag
     9421 ccctacaaaa aacaacaaca aatacccggc aaggcgccgg cagggcgcgt ggatgccccg
     9481 agcgaatacc tagatcaaag caggcagaat tatctagtta aaactttatc aattaatatt
     9541 gaaagttaaa tccgacactc cgccagaggc tcccatactc taggattttc acgcaagccg
     9601 gcatcatata aggttttttt caccaaggga aggggacctg tccttataga taggttgaaa
     9661 atgcctgcgt aagcggaaat ctgctgacgg cagcgttgtg ctgtcgtatt ttttccaagg
     9721 tacatcatgg tcaagaccta ctcccgcccc gttcttcgcg tccagggcca gctcgaagcg
     9781 atgacccacg gcaacagccg gggcagcgct ctggacaaca cctttcaggc cggcactccg
     9841 gtgagccagc ttaccttttc gtaatgcagg ctggcgggcg gcggatcacc gccgcccatc
     9901 tgcgcggcct tccgccacgt cagaacgaat aactggaacc cctgttcaat tcgtacgttg
     9961 aggcgaccat tttcttctgg atttatcaaa gttgtcattc atgacttatc tcgcttcccc
    10021 cgaatgcgtt tcctgcgcgg tcgaagacgg cattgcgatc ctggatctga aatccaacac
    10081 ctatttcagc ctcgatcccg tcggcgcccg gatctgggac cgcatgacgg cgccctcctc
    10141 gcttgaggac ctgaccgccg ccatcgccgc cgaatacgag atcgcccccg gagaatgccg
    10201 gcgcgacatc gccgatcttc tggacgacat gctcaagcac ggcctgatcc gggcggtctg
    10261 acatgggggt cctgcgacgc atccgccgtt tgcgccgccg cgatgccgtg ctgctgtggc
    10321 aggcgctcgg cgcggttcta ctggtgcgcg gctatctggg gcgcggcgcc catcacgacc
    10381 tgcgccggat gatcgaggct catgggctga cgcttcccgc cgccgacccc ggcgcgccac
    10441 gtgccgaact ggccgagatc gcctggtcgg tccgggccgt cgcccggctg gtgccggggg
    10501 cgagctgcct cacccaggcc agcgccggcc agattctact ggcgcggcgc ggccatgcaa
    10561 cgaccatccg gctgtcggtt ccggcgcaga ccgccacgcc cggcatactg gcgccccatg
    10621 cctggctgat ggccggggac accatcgtcc ttggcggcac gcccgaggat tacaaccgcc
    10681 accgcatcct gcacgacttc accctgccgg gcgccggtcc ggcatgagcc gctttgccgc
    10741 catgctgggc catggcccgg atcacgaccc cgccgcctgg cgcatcgcgg ccgacttgac
    10801 ccgccgcacc ggggaaatcc ccggataccg gggggccgag ggcctccatc tgtggcaggc
    10861 cggacggacc ggcagccccg ccacggtgcg gaccctcggc ccgctgacgc tggccgggga
    10921 cctggcgctg accgacctgc ccgagctgcg gggcgcgctg gccgcccatc cgggcagcga
    10981 tcccgccgat ctggtactgg ccgcctggcg gcgctggggc acggatgctc ccgaccgcct
    11041 gaacggtgcc ttcgcctttg tcctgtggga tgcgcggacc cggcgcctga ccgctgtccg
    11101 cgaccgtttc ggcatccagc ccctggccta tgcgctgacc ccgcgccgcg ccgtttttgc
    11161 cagcgacctg tccacggtgc tggcggggct ggatgcggtc cccggcatcg accgcgcctg
    11221 ggtggcgggg ttcctggccg ggcagccgct tgacgccacc gcgacggcct ggggggacgt
    11281 gtcgcgcctg ccccccggcc acctgatgac cctggacccc gacgggaccg ccgccctgcg
    11341 ccgctggtac cggctggaac ggaccgcccc gcccgacccg cgggacgcgg atgccgccct
    11401 gcacgcggcc ttggcccatg cgacggtgca ggcctgcgcc gatggtccca cggccacgat
    11461 gctcagcggc gggctcgatt ccagcacgct ggcgctgctg tcggtcggac cggacgcccc
    11521 cgccccctgc cgccgcccgg cgctgtcgct gcgctaccgc gatccggcca tggacgaggg
    11581 gcgccatatc cacgaggtgc tgcgccggtc gggccgggaa ctcgcccccg tcttcctgcc
    11641 cggagaggcc gaggacgaca cccttttcga catcgacgcc cagcttgact ggcaggacca
    11701 gccggtcttc gcccccgggt tggaacgcaa ccaccgcctt taccgcgccg cgcgggaaca
    11761 gggctgcgcg gcggtgctgg acggccatgg cggcgacgag gtgatcggcg gcagcttccg
    11821 cgacatcgcc ctgatcgccg gggaaggccg ctggccactg gcactggcgc tggccgtgcg
    11881 ccacgcccgc ttcaccggcg agccggtgtc gcaggcgctg gccaccctgc tggccatccg
    11941 cggccggcgc ggcttcggcc ggctgggccg ctgggcgctg aaggacgcag gtcccgaccc
    12001 ccgggactgg cgcgcgctgg tcgatcccga cctcgcccgc gaaacccggc tggtggaacg
    12061 cgcccgcacc gggcaggccc ctacccccga ggaccgccac ctgcccgagg gcgtgcgcct
    12121 gcatgccgcg atgctgaccg gcccgctggc ccccgccgcc tttgaaacga tgggccgggc
    12181 cgcgcaggcc gagggcgtgg cgccgcgcta tcccttctat gaccatcgcg tggtcgagct
    12241 ttgcgtctgg cagcccgaac ccgccaaggt cgcgggcggc cagccccgcg ccctgctgcg
    12301 tcgggcgatg cggggcatcc tgccggaatc ggtgcggatg cgcggggaca agaccgattt
    12361 catcgccggc ttctggggcg cgctgcggcg cgacccgcag ggccgcatcg ccgccctgcg
    12421 ggccgatccc ggccccctgc ggggctgggt ggacacgggc atcctgcgcg cggatgccga
    12481 acgcctggcc cgcgcgcccg agcccgacct ggaaacggcc ttccggctgt ggcggtcgct
    12541 atggcttgcc gcatggctgg aacggcccgc cctgtccctt tcgtcccgcg cccccggccc
    12601 gacccttgcg agtgtccgat gaccgctgtc cctgcccttt ccgccccgcc tcttcaggcc
    12661 catgcctatg ccgcctatgg gctttgcgtg gtgtcggacg ttatcctgcc cgagcttgcc
    12721 cccggaatgc cggggcgtcc ggcagacctg cggatctccg aggcaccgca gcccgcgatt
    12781 ccccgcagcc ccctgcccga ctgccgtttc gggcccgagg ggacatggtt ctggtggccc
    12841 gaggtcgggg ccttctcggt ctcggccgac ggcagccgca tcgggatcga gcgcaggccg
    12901 ggcatctcgg acgacctgct ggccttcccg ctgctggggc cggtcctgtt cgaggcgctg
    12961 cggcggaacg gccttttcgt cctgcacgcc agcgccgtcg tccatcgcgg gcgcggcatc
    13021 gcctttctgg ccgacaaggg cgtgggcaag tccaccaccg ccaccggctt tctgcgaaac
    13081 ggggcgcggc tgctggccga cgaccttgtg gcgatcgacg gcgaggggcg gatgctgccc
    13141 ggcttcggtc aggtcaagct atccgagggc gcggcgcgga tgctgccccc cggcgccacc
    13201 gtccgcggtc ctgtccatga cgcaatcgac aaggcccgcg cgatgctgga ccctgcccat
    13261 ctggcgggga cgccggtccc ggcggcgcgg ctttacctgc tggaacgcgc ccgccggggt
    13321 cagccgtcag aggtgctgcg cctcccccca tccgaggcgc tggcggcggt actgcgcttt
    13381 tcctatgcgg tccgcttcgg cccggcgctg ctgaacggcg cggccgccgc ccagcatttc
    13441 cgcgccgccg cgcaggtggc gctgcgctgc ccgccccggc ggcttttgct ggccgaggga
    13501 ctggaccgcg cccctgacat ccgcgcggcg atcgaccgcg acctcggcga tgactgacgc
    13561 cagcccaccc ttgacggccc cggtccccac cgaggaagcc cgcgcccgaa gccgtggcgc
    13621 tgcgggccag cttgcctcgt tgtggcgggc gctgcggcat ctggaggggc ggcggctctg
    13681 gatcgggctg gcgctgctgg tgctgggcac gctcagcgaa ggcgccgcga tcgtgacctt
    13741 tctgccggtg ctgcaactgg tcggcgcggg cggcacctcg atcgatatgt cggggctgga
    13801 tttccccggc gccgggttgc tgcccgcaat ggtcccgctg ggcgcgctgc tgctggtcat
    13861 cgtcgggctg accgcgctgc aggcgatctt caaccgcagc aaggcggtct acctgtccga
    13921 cctgatccac gacttcacca accaccaccg caccgccctg ttccgcgagg tggcgctggc
    13981 ccgctggtcc catgtcgccc gcatcccccg cacccgcatc gagcatgccc tgaccggcga
    14041 gatcgagcgg ctgtatcttg ccgcctttct tgtcctgtcg atcctgcaga acctggtggg
    14101 gctggcgctg tattttgtcc tgagcctggc gatctcggcg ccgatgacgc tgctgtccta
    14161 tggattcggg gtggtggcgc tggtgctgat gcggcccttc cgccgccttg cccggcatta
    14221 cggcgaccgg ctgcaggcgc ggcgcgaagg ccagcttgcg gcggtgtcgg aattcgtcgg
    14281 cagcctcaag atggcccgca gcatgaacct agaggaccgc tatctggggc ttttttcggc
    14341 gattctgggg caaaccaagg ccgatgcgcg gcagttcatc cgacagtcct cgatcgggac
    14401 gggcttgttc cagttcgccg tggtcagcgg cgccgcgctg ttcatctggg tggcgctggc
    14461 ctgggcgcag cttgatgtcg cccggatcgt gatcctgctt ctgctgttca tgcggacggc
    14521 gccgcgcttc atgggcatcc agggctcggt gcagcagttg ctggtcgacc tgccggcctg
    14581 gggggcgatt tcccggctgc gggacgacct gcaggccgaa cgcgacccgg cgatggcggg
    14641 ccacgatccc gcccccgccc cgcgccggga tatccggctg gaccgggtga gctggcgctt
    14701 tccgggcgaa tcgcgcgaag cggtcagcga ctgttccctg accctgcgcg cgggcgagct
    14761 gacggtgctg gtcgggccgt ccggtgcggg caaaagcacg ctcgccgaca tcgtgatggg
    14821 cctgctggag ccgcagaagg gcacggtgct ggtcgatggc aaggcattgc gccccggcca
    14881 gttccgcggc tggcgcgacc gcaccggcta tgtcgcgcag gagccgttca tgatcaacgg
    14941 cagcatccgc gacaacatgg cgatcgcggc ggccggtcct gtcgatgacg accggatctt
    15001 ccgggcgctc gaccttgcct cggccgggtt cgtgcgggac ctgccggcgg ggctggacac
    15061 gatgatgggc gaccgcggca cgcttctgtc ggggggcgag cgtcagcgga tcgccgtcgc
    15121 ccgcgcgctg ctgcgcgagc ccgacgtgct ggtgctggac gaggcgacaa gcgcgctgga
    15181 ctgggaaaac gaagaagccc tgatccgggc cataggcggg ctgcgcggcc gcatgacgat
    15241 tctggcgatt acccatcgcc ccgcgcttat ccgggtggcg gatgcggtct tcgtgatgga
    15301 atcagggcgc gtgaccgcgt ccgaacgccc gcgcgaacag ggaccgcagg cggaaagcta
    15361 tctgggcaga atgacaagct gatcgggccg cttgcgcgcg ttgcaggccc ggtcccggcg
    15421 cgcggccgcg aataccacga aagccaggat tgcggcctgc aacgcgagaa ccgccacaaa
    15481 ggccagaccg gcaatctgcc aagccgaata tccggccggg attgcccatg ccagcaggcc
    15541 ggaaattacc gccacggcag ttatcaggta atgaatgacg aacatctaaa aaaccttcaa
    15601 cctctggcaa tagtatacca gaggttgcgc caaggaagtt aaaaaatagt taaagtttta
    15661 tggttccccg cggcgacgca gcgtgagacg gctcttcgag cggccgaggt agttttccat
    15721 cgcctcgggc atcaggaatg accgcagctt ccgcaggttg acccggtcat agaccacgcc
    15781 aaggcagttc gcctcaagtt cgggctcttc ggccagaacc gtttcgacca tgctgcgcgg
    15841 ggtccggccc cattccccga cgatcaggaa gcgcggcagc tcgtgcagga tcgcccggcc
    15901 ctgggccacg gggtaaagcg gcggcacgtc cacgatcacg cggctgaact cgtggcaggc
    15961 atcctcgacg atctggccca gcagcttgcc ggtcatcagg tcgtccgaag ctccgcccgc
    16021 ggtcgatccg cagggcagga cattgacgtt ggtgttggcg atgccgacca gcatgctttc
    16081 ccaatcgccg cgccccgcca ccgcgtcggt cagccccggc cgctggtcga ggcccagcat
    16141 cctgctgagg ccgcggcccc ggctgtcggt gtcgatcagc aggaccgatt gcagcccaac
    16201 cccaagctgg ccggccaggt tgaaggcgac cagagaccgc ccctcgtagg gatggaacga
    16261 cgtgaccccg gtcaccggca tcgggctgcc ggatgcctca gtggccagcc ggacatggcg
    16321 cagggtttcg gcataaaccg agtcggggaa atgcagcacc ggcaccggca cattgatgac
    16381 cggcggtttc ggcttcgaca ggaccggaag catctcgccc cgtttcgccg cctgcggcgc
    16441 ggccgaaatg cggggcacgg gcctcgattc aggcagtgcg acctttccgg cgcgaagccg
    16501 gcggacccgc ggcagcaccg gcaggtggcc caggaagcgc agcgccgacc ggtcggtcac
    16561 gtcgctggcg gtccgcagca tccgctcgcg gccttctctc agcgcggcaa gcgccaggcc
    16621 cccgaacagc cccagcaggg tcgcggccag cgtcgtgcgc agcaccgcgg gccccgaagg
    16681 caccgccgga acctgcgcat aggacaggat ccgcacgttc gagaccggga aggactgctg
    16741 ctgctcgatc tcctgcgagc gggtgagcgt ctgctggtac agcgccgaca gggttgcggc
    16801 ctcttcctgc agggcgcgca ggcggacgaa attggcggcc tgggcgctgt tcctctgcga
    16861 ggcctggttg acgctttgct gcagggcctc gacccgggca cgggccacgt cgagggcact
    16921 ctgtgcctcg gcgcgcatgg cctcaagctc gacgaacagg cgttcggccg tgctggccag
    16981 ggtctggcgc aggcccgcca cctgcggatg gttcggcccc gacgaggcca gcaggcgctg
    17041 cagccgggcg cggacgtcgt tgtagttgtc cagccgcgag cgcagttcct cggacatgtc
    17101 gccgccgatg gccagcgagc tgctgctgtc ggtcagcccc tcgacacccc ccgcgaccgc
    17161 gcggtcatag gtgtccagca ccgcctgggc acgggcggcg tcggtcaggg cgacagtcag
    17221 gcccgagttc agctcgttca gcgcctgttc ggtcagcagc ccgcccgagg agaactcgac
    17281 cagcccgttc gcggcggcaa agcgttcggc cgcgttggcg gcggcctgcg cctgcgtctg
    17341 cagctcgtcc aggcggccgc gcatccaggc gttggtctgg cccaccgatt ccgcgttggt
    17401 gaccaggatg tcctgcacat aggcgtcggc ataggcgttg gcggcctcgg ccgcgataaa
    17461 gggatcatgc gagctgaagc tgaccgccac ggccgagctt tgcccgaccc ggtagatttc
    17521 cattcccccc tgcagccgca tcgcggccag gcgccgctcg gggtcgatcg gggcgaccga
    17581 gggatcgccg aagctggtcg ccgagggcag cgcggcaggg tcgatgaccg gggtcgagga
    17641 agtcagcgcc gtgatccggt cctggaccca ggcgatcggg gccagcagcg tgcccatgac
    17701 ccggccgacc aggttcgaga accccgattc cggcgggttc atgaaggacg gattggcctg
    17761 cagcccggtc cggtccagca cgtcataggc cagcttttcc gattcaagga cgacgcgcgc
    17821 attctcgatg cggtcggacg gcagcacggc ggtgtcgatg ccgcccgcct gctggaccga
    17881 tcggttgacg ttgctgtcca gcagcaggct ggagaaagcc tcgtaggtcg cgggcttgga
    17941 ggcggcatag gccagcccca acccgcccag cagcacggcc ggcagcagga tggtccggcg
    18001 ctgccggcgc atcgccacca tcacccggcg caggtcgatg gtctggacct gcgcagcctg
    18061 gcttgcgcca tagggactgg ccagttcaaa cggcttcagg tcgcgcggca tcagttttcc
    18121 tttggtgcgt gtcggggggc gggatctgtc cgaccgggcg ccgttccata gatttcaatc
    18181 tgcggcgccc cgccgagatg ggccgccgcg ccgacatgca gggccgcccg catgatctgg
    18241 cggttgcgcc aggcgggccg ggccgccccc agcagggcca gcccgccgca ggccatggcc
    18301 ttggcggcgg ccacccccgc cgcgccgagc cgtccccccc gcgagcggcc gcgggcgatc
    18361 aggctggcat gggtctgacc catgcggtag cgccgccgca gaagccatgc aagacgggca
    18421 cggtcgggtg gcacgtcctc gtgaacgacg gcgtcaggcg caaagccgat ccggccgccg
    18481 gcggcgagga aatcggcgaa gaaggcgctg tcctccccgc ccgaacggcc gcgggacagg
    18541 tcgaagcgca ggtcccgggc ggccgggtcg gccaggtcga tcaggatgtt gccgctgtag
    18601 cccgacagga ccgccccgtc ctttccgaag accggcagcg tgtcatgggc gcgggcgcgg
    18661 tccatccagc ccggcgcgcc ggcaggataa tgggcctgca ccgggcccag gacggcgccg
    18721 gtccctgccc cggactgctg ccctgccttc caggccgcga cgaggcgggc gagccatgcg
    18781 ggctcggccc tttcgtcgtc gtccagatag accagaaacc gcgcgcctgt ggcgtgggca
    18841 tgatccagca gcgcgttgcg ggcgatcgag atattcgcct cgggcgcgtg cagataggtg
    18901 atgggcagcg gatgggtggc ggcgacctcc tgcacccggt cccgcgccga gggggtgcag
    18961 tcgttgtcgg cgatggcgat cgacacgggc aacccgcagg ggtcaagccg cgccagcgag
    19021 tcgagcgtcg cggcaagctc ggggcggcgg aaggtgcaga tgccgaccag caccgcgtcg
    19081 cgcagaacgg gattgctcat gtggcggccc ttgccggaac ggtctcgcgc cgggaaagcc
    19141 attgccgcca gaaacctgcc gaccaggcca tgtgcatcgt ccccgcgacc aggcccgcca
    19201 gcagcccgtc gggccttttc gtctgcatcg agatgaccac gcccccggcc aggcaagcca
    19261 gcacccacag gacagagggc agcacgaaga ccacgctgaa gggcgccagc ggcaccagcg
    19321 ccgccgccgg ggccagcatc gccgcaaggg cctgccgcgc cgccggccgg gcgttgtgct
    19381 tgatgaggtt gcgcgcccgg ccgcggccga aattgtaata ctgccgcatc agcgcccgga
    19441 tgctctgccg cgggaaatag gtcaggcggg tccgggaggt cagccagatg cggcgccccg
    19501 ccgcggacag gcggcggtcc agctcggcat cctcgttgtg gctgaagctt tcgtcatagc
    19561 cgccgacctc gcggaaggcg gcgacctgca tcagcgcgtg atggccgtga tcgacccagg
    19621 catcgccccc cgccagccgg tgcgccgagc caccgttgcc aaagggcgag ttctgggcgt
    19681 cggcgatgat ccgctgcagg aagccttgcc cttcggcatg catcgagacg accacgctgg
    19741 ccgcgcccgt gcgccgggcc tcggccagca ggacatcgcc gtaatcggcg ggataggtgc
    19801 tgtgggcgtc aaggcgcaga agccattccg ccccctggcc gaagcgctcg acggcaaggt
    19861 tcacggccgc cgcctgcagc cgccgggggt tgtgcagcag gcggatgcgc cggtggtcgg
    19921 cggcgcggcg gcggacgatg tcgcaggtcg catcgcgcga gccgccgtcg gccaccacga
    19981 ccagcccgtc ggcgcgttcg gcgaaggcca cggcgaaatc gagcacgccc gcgatatgcg
    20041 ccgcctcgtt gagggtgggg atgacgatca gcactttggg gtcgggaaac atgggcatgg
    20101 cgatgctatc cggtgatcgc ggggacgggg gcggttctgg ccgcagggac gggggaagcg
    20161 ccgcagatgg ccgcggtcag gcgccggcat tcggccctgt ccatttccag ccggtcgcgg
    20221 ggaatggcag ccaccgcccc gcgcagcctt gcaagcccga ccgggtccag cgccgacagc
    20281 gcccctgcca cggcctcggg gccggggtcg gcgacaacca cgccgcaatc ccagccggcg
    20341 acccggcgcg cgacctcggt tccctccagc gcgaccggga cggcgccgtt caggcagccc
    20401 tcgtacagcc ggttgggcag cagccagtcc gagttctgcc cggcctggta gcggtcgatc
    20461 agccaggcca cgtcgacgcc cccgtagatc gcgggcaggt cgccgggcca gtcatagggg
    20521 ccgcggaact ccatgtcggg gttggcgccg atgatggcgt ggaaatccgg catcacgtcc
    20581 agcgccgggc gcccgcgcag caccacgcgg aaccgccccg gccgcgaccg ggtgagccgg
    20641 tcgagcgtct tcagcgacca gtcatcgcgc agcatcccga accagccgat gaccaggggg
    20701 ccgccttcct caagcccgcc gggggcggga ccggcctggc ggggaccggc atcggggcgg
    20761 gcgaagggct tgttctcgac cagcagggcc ggcaggtcgg gctggccatg ggggcgcagg
    20821 tagcgggcgg cgaaggcggg cgaggacagc accaccagcg cggcccggcg catcagcccg
    20881 gcctcgaccc ggcgcaggct gcgggcgacg gccccctgcc ccagcatcat gccgtggatg
    20941 tccagaagct cgtagaccag ccgggcgcgg cccttgcggg cgcgcaccag ccttgcgcca
    21001 agagccagca tctcgaggtt gcgggccagc acgacctcgg gttcgccatg gccgtccggg
    21061 ggcgggaccc gccgggcaag acccggccat gccgccagga tcgcgcggac ccgctggccc
    21121 atgcgcgcgt tgacggtgcg gcccagaacg atcgcgggtt cggcaagcgg cccatccccg
    21181 cgacggaaac ccgcgacccg gacgctggcg ccgccgcggc gcagcatctc gacccgccgc
    21241 cagatcgacg ggtcatcgag gtcatgggca agataggtca cgtgcaatat cgtctccggc
    21301 agaaaaagcc gatggaaatg ggtcagaata tgggccgggc cggagatcgg acttgtcatc
    21361 cccaaggccc tggccagtct tcgcgcgtga tagcgaactg cacaacggcg gaaaaccgcc
    21421 aaacacctca aattgtctaa agagacaggt ggcagaatgg cacagcgatc accggggcgt
    21481 cagaacggga aaaaagacct gcaaggatgc cgccatttcc ggtgttgcgt tttccgcagc
    21541 cgcaacgcgc gccctgaaag ccggttgtta acgcatcatt cataatttcc cccggacggc
    21601 gcaggaacga ccgctttccg cgcgcaatcg aggggcaaag atggccgaca acctgccgcc
    21661 cgggattccc gcagaccctg acaggggcgc tggcccccgc ctgcccggcc attccctttc
    21721 cggcggccgg atgccgcgcc cggcgggggc catggcggcc tgacccccgg cggcacaacc
    21781 acgacatcac cgcggaaagc ggccgcgggc cttcgggccg gcggcgggcg atccgccaca
    21841 ttccggggcc gccgaacggc aaggcccctg aaccctgcat ccacaaggaa gaaagacgca
    21901 tggcctacga tcccgacctg aacgtgatct tcgacggcat gaacacacaa ttcgcagcca
    21961 tcaaggcgcg gctggacaag ctggaaaagg gcgcgcccgc gcctgccccg gcccctgcac
    22021 ccgcgcctgc gccgaccccc gcaccggcac cggccccgac gatgaaccgg caggcgctcg
    22081 gctttgcggt gccgcgcaac gagctggcga agaacccggc ggggatgctg gaccgcatcg
    22141 ccgccaccgg cgcccgcatg atccgcttcg acttctattg ggaccagatc gagcgcagcc
    22201 agggcggcgc cttcgactgg gccggcgtcg aggcgctggt gaacgcggcc ggccagcgcg
    22261 gtatccaggt gctgggcatc ctgaccggga agcccgcctg gggcagcgat gaaagcctga
    22321 gcgatcccgc cgacgccgcc cgcttcggcc gctttgccgg ggccgccgcc gccaggttcg
    22381 cgggccgggt cgatcactgg cagatctgga acgagcccaa cctcaaccgc atgacgcccg
    22441 agcgttacgt gcccgtgctg aaggccgccc atacggaaat caagcgcgcc aatcccaagg
    22501 cctttgtcgt gggtgcgggc ctgtcggccg tgcccacgac cactggcggc agcatcggcg
    22561 tgcgcgactg ggtgacgcgc tgctatgcgc ttggggccaa gggtcattac gacgcgctgg
    22621 cg
//
