LOCUS       NZ_CP067225            20864 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Paracoccus sp. MC1862 chromosome, complete genome.
ACCESSION   NZ_CP067225
VERSION     NZ_CP067225.1
KEYWORDS    RefSeq.
SOURCE      Paracoccus sp. MC1862
  ORGANISM  Paracoccus sp. MC1862
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Paracoccaceae; Paracoccus.
REFERENCE   1  (bases 1 to 3307010)
  AUTHORS   Mingchao,X.
  TITLE     Paracoccus sp.MC1862
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3307010)
  AUTHORS   Mingchao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) Chinese Center for Disease Control and
            Prevention, National Institute for Communicable Disease Control and
            Prevention, Changping, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. HGAP 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 282.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016617715.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:33:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,607
            CDSs (total)                      :: 3,551
            Genes (coding)                    :: 3,394
            CDSs (with protein)               :: 3,394
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 65 of 157
            Pseudo Genes (incomplete)         :: 116 of 157
            Pseudo Genes (internal stop)      :: 29 of 157
            Pseudo Genes (multiple problems)  :: 44 of 157
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:42:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2638279
            Orig. end                         :: 2659143
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067225.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20864
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20864
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20864
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10864](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10864)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(129..144)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            complement(714..1013)
                     /locus_tag="JGR78_RS12985"
                     /old_locus_tag="JGR78_12985"
     CDS             complement(714..1013)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017998648.1"
                     /locus_tag="JGR78_RS12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_12985"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_182792842.1"
                     /transl_table=11
                     /translation="MATAPAKPMTKTQLVAALADEMGSDKKTATAALDALGALVARTVA
                     EGGALTLPGIGKVACRARPERQVRNPQTQEMMTKPADKVVKVTIAKSLKDSVNA"
     gene            complement(1043..2002)
                     /locus_tag="JGR78_RS12990"
                     /old_locus_tag="JGR78_12990"
     CDS             complement(1043..2002)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS12990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGR78_12990"
                     /product="hypothetical protein"
                     /protein_id="WP_200559335.1"
                     /transl_table=11
                     /translation="MMAPVALIQQEVQSRIGDGTDPVIYRNALIARFALDLPQTVAALS
                     LPASALALYPDLARRLAETIPAEFPDYEADSLARDVAHVFGFFIPGAAMDIDRFGRLDP
                     RMIASAAVRCRQLTAPARYVWGGMWRPFLEFHTDSRHLTGFNPAGFHATYLQVADMLRC
                     NPALAGLFISSWFHDPIAAEISPRLAYLQGVPRAGGAFFIRNNTGELHVKRATATSATR
                     RQLVADGKYVPTCYTMIWPRKKLIAWADGINKGRRDAGGLAAPAVAPSGAMSLASDAHF
                     HRPSLKSTPWPLQKGLKRGEKPAVAGAMPDQLAPEMPA"
     misc_feature    2091..2106
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(2096..2110)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.31"
                     /tool="antismash"
     misc_feature    complement(2097..2110)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.73"
                     /tool="antismash"
     gene            complement(2273..3754)
                     /locus_tag="JGR78_RS12995"
                     /old_locus_tag="JGR78_12995"
     CDS             complement(2273..3754)
                     /EC_number="3.2.2.4"
                     /GO_function="GO:0008714 - AMP nucleosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0044209 - AMP salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011746751.1"
                     /locus_tag="JGR78_RS12995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_12995"
                     /product="AMP nucleosidase"
                     /protein_id="WP_182792844.1"
                     /transl_table=11
                     /translation="MDQLSRLLPVETPEPVEREYFDDPQAAVARLIELHDRATGWLLDR
                     FVGTLRGGHPPAARFRAFYPEVRLTTSSHEQADSRLAFGHVTLPGTYAATITRPDLFRD
                     YLTQQIGLLIRNHQVPVAVGESDTPIPVHFAVATQSDLNVPQEGVLDYSLRDIFDVPDL
                     VTVNDNIVNGIADELPDGTRHLAPFTAQRVDYSLARLAHYTATAPDHFQSFVLFTNYQF
                     YVDEFEAFARKALADPASGYTAFVGPGNHMIERPDDASVPVAKTPQMPAYHLKRPDGQG
                     ITLVNIGVGPSNAKTATDHIAVLRPHAWLMVGHCAGLRNSQRLGDYVLAHAYLRLDHVL
                     DDDLPVWVPLPTLAEVQVALEQAVAEITELEGFELKRIMRTGTVATIDNRNWELRDTPV
                     HRLSLSRAIALDMESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPGMATDFYRTQVS
                     SHLLIGIRAMEKLRATPIERLHSRKLRSFHETAFL"
     gene            3836..4825
                     /locus_tag="JGR78_RS13000"
                     /old_locus_tag="JGR78_13000"
     CDS             3836..4825
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007427034.1"
                     /locus_tag="JGR78_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13000"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_182792845.1"
                     /transl_table=11
                     /translation="MDISILDLAPVPEGSDTKAAIASSVTLARAAEAQGYKRFWLAEHH
                     NMPGIASAATAVLIGHIADHTKDIRVGAGGIMLPNHAPLAVAEAFGTLATIHGPRIDLG
                     LGRAPGGDGAVMHALRRGQSRNEDFPNDVVELLHYLGPERPGVAVAAHPGQGTNVPVWI
                     LGSSLYGASLAAALGLPYAFASHFAPDALDDAVALYRDRFQPGPWGDKPRFMLAANLIA
                     ADTDAEARRLRTSSQIQFFRLRTGNPGLLPAPVDDLDAVVPAQYQSMVDRVLSVSAVGA
                     PDTVKAQIDAMVARYKPDELILTGNIWDPAAREKSFAIGAEVLGLTRA"
     misc_feature    3842..3856
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            4822..5688
                     /locus_tag="JGR78_RS13005"
                     /old_locus_tag="JGR78_13005"
     CDS             4822..5688
                     /EC_number="1.1.1.290"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012179951.1"
                     /locus_tag="JGR78_RS13005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13005"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_182804072.1"
                     /transl_table=11
                     /translation="MTSRLVVLGHGYSAGFLTRRLVPQGWTVTGTTRDNASRVTLAGAT
                     PLRWPGEGDAVRAEIARADAILISAGPEAGECPALREFGTAIADSRARWFGYLSTTGVY
                     GDRQGGWVDETSDLAPSTRRGRDRVAAEAGWQALAAAHGLPLHIFRLAGIYGPGRGPFE
                     KVRNGTARRIIKPGQVFSRIHAEDIAQTLAASIARPSPGAIYNLCDDDPAPPEDVLEHA
                     AHLLGLPPPPAEDFTTAEMTPMARSFYAESKRVSNARIKRDLGIRLIHPDYRSGLAAIL
                     AEESVRA"
     gene            complement(5678..6286)
                     /locus_tag="JGR78_RS13010"
                     /old_locus_tag="JGR78_13010"
     CDS             complement(5678..6286)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019844.5"
                     /locus_tag="JGR78_RS13010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13010"
                     /product="COG3650 family protein"
                     /protein_id="WP_182792847.1"
                     /transl_table=11
                     /translation="MRLAALALTLALAGPAAAQSMLPTLYDVTGVKSNDVLNIRAMPDA
                     SSSILSELPHDATGVEVIETRSGWARVNTFERSGWVNMRYLQERPDVWKPGEIPATLNC
                     LGTEPFWSLRQVGANIVYETPELSRPLQRRVVVDNPARREPARSIIAGDAQGRLTVVLT
                     PAQCSDGMSDRAFGLSATLLFEGADQASRMENGCCRITP"
     gene            complement(6305..7018)
                     /locus_tag="JGR78_RS13015"
                     /old_locus_tag="JGR78_13015"
     CDS             complement(6305..7018)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017997929.1"
                     /locus_tag="JGR78_RS13015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13015"
                     /product="VIT family protein"
                     /protein_id="WP_182792848.1"
                     /transl_table=11
                     /translation="MTRNTHPDAHPDDPHYITRSNWLRAAVLGANDGIVSIGSLVVGVA
                     TASGDPQAVMIAGGAGLAAGALSMAAGEYVSVSSQSDIEAADIHRERQALHHQPEIELE
                     ELILIYESRGLAPDTARLVACELTEHDALGAHLRDELGLTEELSADPMQAAMASGATFT
                     VAGGVPYLAALLTPLGLIVPVVLAVTLIALAALGMLGAWAGGAPLRPALVRVLLWGSFA
                     MAVTSVIGHLFGAVV"
     gene            complement(7094..7999)
                     /locus_tag="JGR78_RS13020"
                     /old_locus_tag="JGR78_13020"
     CDS             complement(7094..7999)
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016362.5"
                     /locus_tag="JGR78_RS13020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13020"
                     /product="restriction endonuclease"
                     /protein_id="WP_182792869.1"
                     /transl_table=11
                     /translation="MLPILRMIGEGKQSIADSLPGLQKQFLLSDTQMEMLLPSGTQSYM
                     SNRAHWARNYMMHAGLVEPIKRGHYRITPAGKALLDSNPTKIDKNTLRTYPDFLEWLTY
                     LAGRSKEAPEVPVFGASEPQDTTETPQELIDSAHAALQDALAEELLEQLLAVTPARFEQ
                     VIVDLLIAMGYGSGRAEMGRAIGKSGDGGIDGIINEDKLGLDAVYIQAKRYKPENAIGR
                     PALQGFVGSLIGARARKGVFVTTSSFTKEAWGYVRGIEQRVVLIDGARLARLMIDHGVG
                     VRTSATYVIRRIDEDYFSVD"
     misc_feature    7979..7997
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            complement(8032..9954)
                     /gene="dxs"
                     /locus_tag="JGR78_RS13025"
                     /old_locus_tag="JGR78_13025"
     CDS             complement(8032..9954)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017998654.1"
                     /locus_tag="JGR78_RS13025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13025"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_182804074.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 8.1e-118,
                     bitscore: 390.1, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTSRPATPILDRVASPADLKALSDRQLHQLADELRAETISAV
                     SVTGGHLGAGLGVVELTVALHAVWDSPRDKIVWDVGHQCYPHKILTGRRDRIRSLRMEG
                     GLSGFTKRSESPHDPFGAGHSSTSISAALGFAAARDLGGDPGDAIAVIGDGAMSGGMAF
                     EAMNNAGHMGTRLFVILNDNEMSIAPPTGAMSSYLTRLYTQGPFQELKAAAKGAVSLLP
                     PPMQEGARRAKEMLKGITIGGTLFEELGFSYVGPVDGHDLDQLLPLLRTVKARADGPVL
                     IHAVTKKGKGYAPAENAADRGHARAKFDVITGEQAKAKSNAPSYTSVFAKSLIAQAERD
                     DRIVAITAAMPDGTGLNLFADRFPRRCFDVGIAEQHAVTFSAGLAAGGMRPFCAIYSTF
                     LQRGYDQVVHDVAIQRLPVRFAIDRAGLVGADGATHAGAYDVGFLANLPGFVVMAAADE
                     AELVRMVATAVALDDRPSAFRFPRGEGTGVELPERPEPLEIGRGRIVAEGARVAILSFG
                     TRLSEVLRARESLMARGLAPTVADARFAKPLDRDLILRLVREHEALITIEEGAIGGFGS
                     HVAQLLAEEGVFDRGFRFRSMVLPDTFIDHASPEAMYRAAAMEAPQIEAKVLEVLGVAA
                     LGRRA"
     gene            complement(10001..10864)
                     /locus_tag="JGR78_RS13030"
                     /old_locus_tag="JGR78_13030"
     CDS             complement(10001..10864)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009570299.1"
                     /locus_tag="JGR78_RS13030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13030"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_182804076.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.2e-54, bitscore:
                     181.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHQRLEEAQRATASAIEAALADLPSGDLTDAMRYATNGGKRIRAF
                     LVLESARLFGVEDLSAMPVAVAVELLHAYSLIHDDLPAMDDDDLRRGQPTCHVRWIEAT
                     AILAGDALQTQAFAMLSDPVIGPAEARIALVARLAEASGARGMVWGQAQDIAAETAGTP
                     LDLPAIEALQHAKTGALIRFAASAGAIIGGTDPAPLQDYAHYLGLAFQIADDILDVTAS
                     VEQTGKRTGKDQAAGKATFVSLLGLEEARARATQMVVRAEAALDSYGDRAGNLRALARF
                     VIHRKT"
     gene            complement(10867..11109)
                     /locus_tag="JGR78_RS13035"
                     /old_locus_tag="JGR78_13035"
     CDS             complement(10867..11109)
                     /EC_number="3.1.11.6"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011746745.1"
                     /locus_tag="JGR78_RS13035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13035"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_182792851.1"
                     /transl_table=11
                     /translation="MTDAEIDQMSFEDAMKELESVVGKLEHGEATLEQSIALYERGAKL
                     RAHCERRLRQAEERVEKIMLAANGEPSGTAPVEGL"
     gene            complement(11106..12017)
                     /locus_tag="JGR78_RS13040"
                     /old_locus_tag="JGR78_13040"
     CDS             complement(11106..12017)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008883522.1"
                     /locus_tag="JGR78_RS13040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13040"
                     /product="histone deacetylase family protein"
                     /protein_id="WP_182804078.1"
                     /transl_table=11
                     /translation="MTILYTHSASERHLTPSGHPEQVARHKAVLDGLADLKLDRREAPL
                     AAEADMLRCHPERYLARLKAAVPAQGQVALDPDTWLSPGSMEAAMRAVGAACAAVDAVL
                     GGEDSRAFVAMRPPGHHAERETPMGFCLLGTAAIAAMRALDHHGLDRVAVLDFDVHHGN
                     GTQDLLWDESRAFFASTHQMPLYPGTGRASETGAHGQVMNVPLPPGSGGAQARAAWRQI
                     MDRLQAHAPQLVIISAGFDAHAADPLAALEWEDDDFAAITRMICDAAGAAPVVSVLEGG
                     YDLAALGRSARAHVTALEGTGP"
     misc_feature    12186..12200
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.39"
                     /tool="antismash"
     gene            complement(12214..13464)
                     /gene="mtaB"
                     /locus_tag="JGR78_RS13045"
                     /old_locus_tag="JGR78_13045"
     CDS             complement(12214..13464)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0061712 - tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="mtaB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012179889.1"
                     /locus_tag="JGR78_RS13045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13045"
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="WP_182804080.1"
                     /sec_met_domain="PF04055 (E-value: 4.7e-22, bitscore: 76.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPPIFATLGCRLNAYESEAMAEMAREAGLNGAVIVNTCAVTAE
                     AVRKARQEIRRLSRENPGAPIIVTGCAAQTEPDTFAAMPEVARVIGNHEKMQPATWASL
                     AAPDYGTERVMVDDIMSVRETAGHLIDGFGRHRAYVQVQNGCDHRCTFCIIPYGRGNSR
                     SVPAGVVVDQIKRLRDRGFNEVVLTGVDLTSWGADLPGQPRLGNLVRRILRMVPDLPRL
                     RISSIDSIEADPELMEAIATEPRLMPHLHLSLQHGDDLILKRMKRRHRRDDAIAFCEEA
                     RRMRPGIVFGADIIAGFPTESEAHFENSVKLVQDCGLTFLHVFPYSARTGTPAARMPRV
                     PGPAIKDRAARLRAVGKAALAAHLQAQVGRSHRVLTEGPRIGRTEQFTEVSFAHDLPEG
                     ALVEVTITGHDGARLAA"
     gene            complement(13461..14315)
                     /gene="dapF"
                     /locus_tag="JGR78_RS13050"
                     /old_locus_tag="JGR78_13050"
     CDS             complement(13461..14315)
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapF"
                     /inference="COORDINATES: protein motif:HMM:TIGR00652.1"
                     /locus_tag="JGR78_RS13050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13050"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_200559336.1"
                     /transl_table=11
                     /translation="MCAYIAAMEQENPGGLGFVKMHGAGNDFVIIDSRGAPQRRVTPAL
                     ARALGDRNRGVGFDQLAEICPDDAADYRLEFWNADGSGAGACGNASRCVADLMMRDPGR
                     DRVRFSTLRGMLEAERRDGQVHVNMGHPQLAWDEVPLAREMDTERLPLDGGPAAVGMGN
                     PHCVFFVPDAEAVDLTAIGPRIEHDALFPERTNVEFASLTAPDRLRMRVWERGAGVTLA
                     CGSGACATAVAAHRRGLTGRRVVLDLDGGTLVVDWREDGVWMTGPVARVFEGVLSPEWL
                     AAT"
     tRNA            14391..14466
                     /anticodon=(pos:2652703..2652705,aa:Lys,seq:ttt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="JGR78_RS13055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="JGR78_13055"
                     /product="tRNA-Lys"
     gene            14391..14466
                     /locus_tag="JGR78_RS13055"
                     /old_locus_tag="JGR78_13055"
     misc_feature    14470..14484
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.51"
                     /tool="antismash"
     misc_feature    14576..14585
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    complement(14852..14863)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            14971..17949
                     /locus_tag="JGR78_RS13060"
                     /old_locus_tag="JGR78_13060"
     CDS             14971..17949
                     /GO_function="GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009565138.1"
                     /locus_tag="JGR78_RS13060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13060"
                     /product="monovalent cation/H+ antiporter subunit A"
                     /protein_id="WP_182804084.1"
                     /transl_table=11
                     /translation="MLAQNLLLLLAVLPFAGAILAVTMPVTARNAEVVLAGGVMIAGLL
                     ALFAVMGDVADAQAVARSIEWAPSLGLDLTLRLDGFSWLMLLLVYGIGLLVVIYARYYL
                     SPSDPVPRFYGFLLAFAGSMVGMLISGNIILMVVFWELTSLFSFLLIGYWNHNAAARDG
                     ARTALIVTGGGGLCLLMAMILLGHAAGSYHLDDVLAAGDRVREHPWYLWILGLFLIGAF
                     TKSAQFPFHFWLPNAMAAPTPVSAYLHSATMVKAGVFILVRFSPVLGGTDAWFWIVAGT
                     GMLTLLLGAVIALWRNDLKGLLAYSTISHLGLITALCGMGSGGAIVAAIFHIMNHAVFK
                     ASLFMAAGIIDHETGTRDMRRLSGLRHSMPRTAALAIVAAAAMGGVPLLNGFLSKEMFF
                     AEAADWHNGTWLDAALPYIATIASTFSVAYSLRFIVTVFFGPPATDLPKEPHEPPAWMR
                     RPVEFLVAIVLLVGLWPAALIGGPLHAGVLAVLGENAPYYSLSLWHGFNVALTMSIVAL
                     VAGTILYFLMARRLSEANEAPAFLSLVRGQQVFDRLMLVLTRKWPAWAYRRVGSPRLQV
                     QLRLLVLLSLGATAATLWGAARLVPEGLLQNFDATFALLWMGGIACAIGAAIQAKYHRF
                     AALALLGSAGLVTAVTFAWFSAPDLAVTQLLVEIMTTVLLLLGLRWLPKRMKLIEGDDR
                     FTARRRRGIDFVVATVCGAGVAAIAFAVMTTPAGLTIGDWFRRNSYAEGGGTNAVNVIL
                     VDFRAFDTLGEITVLGIVALTCYALLRRFRPAPESVALPSQQTFNELPPLDPEREREAE
                     REPTRHDVMMMIPSVIMQWMFPLTVALSMYLFLRGHDLPGGGFAGGVAFAIGLLLQYLA
                     RDVRWVESRITILPVRWIGLGLVIAVATGMGSFLFGYPFLTAHAQYVTLPVIGQVPAAT
                     ALVFDLGVFATVVGAAVLIQIAIAHQSLRSSRLRARETAADADPKEEQENRHEEQEQQR
                     EGV"
     gene            17949..18293
                     /locus_tag="JGR78_RS13065"
                     /old_locus_tag="JGR78_13065"
     CDS             17949..18293
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003250128.1"
                     /locus_tag="JGR78_RS13065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13065"
                     /product="Na+/H+ antiporter subunit C"
                     /protein_id="WP_182792581.1"
                     /transl_table=11
                     /translation="MELTLSLGIGVLVASGVWLTLRPRTFQVIVGLCLLSYGVNLFIFA
                     MGRLVTGAAPIMPKGGFVNPDAYADPVPQALVLTAIVISFATTALFLVVIMASRGLTGT
                     DHVDGKERGQ"
     gene            18290..19915
                     /locus_tag="JGR78_RS13070"
                     /old_locus_tag="JGR78_13070"
     CDS             18290..19915
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002723154.1"
                     /locus_tag="JGR78_RS13070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13070"
                     /product="monovalent cation/H+ antiporter subunit D"
                     /protein_id="WP_234450748.1"
                     /transl_table=11
                     /translation="MISPAHIVVLPILIPLLAGAIMLMYDERQRRLKLGIGILSCVLQL
                     AVAIALVDRAGGSADMGRNMVTLYLLGDWPSPFGIVLVLDRLAAVMLLLGSIIALPALL
                     YAGAGWHRNGQHFSPLFQFLLMGVNGSFLTGDLFNLFVFFEVMLAASYGLLLHGTGRVR
                     VAAGLHYIAVNLVAAMLFLLGVSLIYGATGTLNMADLASRIPRLSEADRPMVHAAAALL
                     SGAFLVKAAMWPLCFWLPNAYGAASPPVAAIFSLLTKVGAYVVIRLGLLLFGAGAGESA
                     GFGANVLAAGGMATMIFGALGVLQAQDLGRMTGNLVLVSSGTLLAVVGLAQIYDDAPML
                     TAALYYMIASTIAIAALFLLAEPIGRKEGGIAGLLAITAEAYADPEEEIDEPTDEGRAI
                     PGATALLGVAFLACVLVVAGLPPLAGFLGKFGMLSGAVERAKVLPGMWGHWAFVVLLIV
                     TGFCALVAMVRWGIQSLWANTEEPPLPMLEIVPILMLVATVVLLSIRAEPALRYLDRTA
                     DALTQNQVYIGGVLTAPPVGSDDP"
     gene            19912..20397
                     /locus_tag="JGR78_RS13075"
                     /old_locus_tag="JGR78_13075"
     CDS             19912..20397
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013067838.1"
                     /locus_tag="JGR78_RS13075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13075"
                     /product="Na+/H+ antiporter subunit E"
                     /protein_id="WP_182804087.1"
                     /transl_table=11
                     /translation="MTLFPHPIVTVVLTILWMVLTSFTPGQFVLGVIAGILGGLAYRRL
                     TPERIMVRRPRQIIRLFFRVGGDIIRSNIAVAGLILTQGRGGRRRAGFVPIPLDMTSPN
                     GLAVLAIIVTATPGTAWIEYEPRNGLLLLHVFDLLDEDDWVHTIKSRYESLLMEIFE"
     gene            20394..20675
                     /locus_tag="JGR78_RS13080"
                     /old_locus_tag="JGR78_13080"
     CDS             20394..20675
                     /GO_function="GO:0015075 - monoatomic ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002723151.1"
                     /locus_tag="JGR78_RS13080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_13080"
                     /product="K+/H+ antiporter subunit F"
                     /protein_id="WP_182804089.1"
                     /transl_table=11
                     /translation="MSATILSVVLTFSQICLVISVVLSVLRALRGPRAQDRVLGLDTMY
                     MCAMLLLVVTGMQQGTIYQFEAALVIGTLGFVATAAMAKFLMRGEVIE"
ORIGIN
        1 gcggttccgg cgcagcaggt acatgggcga ttccggcacc cagagccgca ggaagatgcc
       61 gatgcaggcg ggcagggccg ccaccaggta gatcagcttc catggcgccg cgaccgcgaa
      121 gcttgccgcg aaccaggcgg tcagcgcgac gaccagcgtg cccagcgccc agaagccctc
      181 cagccagacc agccagcggc cgcggttctt cggcggcagg aactcggcca tcatggcata
      241 gtccacgggc agggtgccgc ccaccgccat cccggtcagg aagcgcagcg ccagcagcca
      301 ctggaagtcg ggcgaaaaga ccgaggccag cccgaagacc gcgtcgcagg ccaccgtcac
      361 gatcagcacg ttccgccgcc cgatccggtc cgccagccgc ccgaacagcg ccgcgccgac
      421 gaacatcccg agaaagaaca gcgtcccgct ttgcagcgcc acctgcatct ccagcccgaa
      481 gctggccgcg atcgagggtg cggcgaagcc gaccgccacc acctgcatgg cgtcggccgc
      541 ccagaccagc ccgaagatcg ccatcaggcg acgctggaaa cggcccgcgc ccgcctcggc
      601 cagcgcgtcg tccaccgtga tcctcatcgc ggttcctccc cttgcctcgc cccttgcaaa
      661 aaggggccgc gccctcgcgc gacccccgga tgcttcgcca gccacaaggg cagtcaggcg
      721 ttgacgctgt ccttcagcga cttggcgatg gtgaccttga ccaccttgtc ggcgggcttg
      781 gtcatcattt cctgcgtctg cgggttgcgg acctgacgct cggggcgggc gcggcaggcg
      841 accttgccga tgccgggcag cgtcagcgca ccgccctcgg cgacggtgcg ggcgaccagc
      901 gcgcccagcg cgtccagcgc ggcggtggcg gtcttcttgt cgctgcccat ctcatcggcc
      961 agtgcagcca ccagctgcgt cttggtcatg ggcttggcgg gtgctgtggc cataggtcct
     1021 gtctcctcgt gtgtcgcgcg cgtcaggcgg gcatttccgg cgccagttga tctggcatgg
     1081 cccctgctac agccggtttt tccccgcgtt tcaagccctt ttgaaggggc caaggggtgc
     1141 ttttaaggct tgggcgatga aaatgggcat cagacgccaa gctcatggcc ccggaagggg
     1201 caacggcagg ggctgccagc ccaccggcat cgcgccggcc cttgttgatg ccgtcggccc
     1261 aagcgatcag cttcttgcgc ggccagatca tcgtatagca ggtcgggacg tattttccgt
     1321 cggcaaccaa ctggcggcgg gtggccgagg tggcggtcgc ccgcttgaca tgaagctcgc
     1381 cggtgttgtt gcggatgaag aacgcgccgc ccgcgcgggg gacgccctgc agataggcaa
     1441 gccgcgggct gatttctgcg gcgatgggat catggaacca ggacgagatg aacagccccg
     1501 ccagtgccgg gttgcatcgg agcatgtcgg ccacctgaag gtaggtcgcg tgaaagccgg
     1561 ccggattgaa cccggtcaga tgccgcgaat ccgtatggaa ctccaggaac ggtcgccaca
     1621 tcccgcccca gacataccgc gcgggggccg tcagttgcct gcaccggacg gccgcggacg
     1681 caatcatgcg cggatcgagg cgtccgaagc ggtcgatgtc catcgcagcg ccggggatga
     1741 agaaaccgaa cacatgggca acatcccgcg ccagcgaatc tgcctcatag tccgggaatt
     1801 cagccggtat cgtctcggcc agcctgcggg caagatcggg atagagcgcg agggcggatg
     1861 ccggcaggct cagcgcggca accgtctgcg gcaggtcgag cgcaaagcgg gcgatcagag
     1921 cgttccggta gatgacggga tcggtcccgt ccccgatccg gctctggact tcctgctgga
     1981 tcaaggcgac tggcgccatc atcccctttt gccgtatcgc cgcctccgcc tcggcaagca
     2041 gtcccgcgcg tcgcgcctga tagtgatctt ccagctgacc accggcacgc gtgacgattt
     2101 cttcaaaaat ggcccgcgta tgcttgggga tctcgaaact gctcattgat gaaaactctg
     2161 cgcttgcaat cctgtcatcc cagtagcttg agaagcagac tcccgtcagc ttgtataaag
     2221 cgacaggcgg cggcgttctg gcgcacggcc cgtggtccgc gcagcgtccg atttacagaa
     2281 acgccgtctc gtggaaggac cgcagcttgc gggaatgcag ccgctcgatc ggggtggcgc
     2341 gcagcttctc catcgcgcgg atgccgatca gcaggtggct ggagacctgc gtgcggtaga
     2401 aatcggtcgc catgccgggc agcttcaact cgccatgcag gggcttgtcg ctgacgcaca
     2461 gaagcgtgcc gtagggcacc cggaagcgga agccgttggc ggcgatggtg gcgctttcca
     2521 tgtccagcgc gatcgcgcgg ctgaggctga ggcggtggac cggcgtgtcg cgcaattccc
     2581 agttgcggtt gtcgatggtg gcgacggtgc ccgtccgcat gatccgcttc agctcgaagc
     2641 cttccagctc ggtgatctcg gccacggcct gttccagcgc cacctgcacc tcggccagcg
     2701 tcggcagcgg cacccagacc ggcaggtcgt cgtccagcac atggtccagc cgcaggtagg
     2761 cgtgggccag cacgtaatcc cccagccgct ggctgttgcg cagccccgcg caatggccga
     2821 ccatcagcca ggcatggggg cgcaggacgg caatgtggtc cgtggcggtc ttggcgttgg
     2881 agggtcccac gccgatgttg accagcgtga tcccctgccc gtccggccgc ttgaggtgat
     2941 aggccggcat ctgcggggtc ttggcaacgg gcaccgaggc atcgtccggc cgctcgatca
     3001 tgtggtttcc gggaccgacg aaggccgtgt agcccgaggc ggggtccgcc agcgccttgc
     3061 gggcaaaagc ctcgaactcg tccacgtaga actggtagtt ggtgaacagc acgaaactct
     3121 ggaagtgatc gggcgcggtc gcggtgtaat gcgccagccg cgccagcgag taatccaccc
     3181 gctgcgctgt gaagggcgca aggtggcggg tgccgtcggg cagctcatca gcgatcccgt
     3241 tcacgatgtt gtcgttcacg gtgacgaggt cgggcacgtc gaagatgtcg cgcagggaat
     3301 aatccagcac gccttcctgc gggacgttca ggtcgctctg ggtcgccacg gcgaaatgga
     3361 cagggatggg cgtgtcgctt tcaccgacgg ccacgggaac ttggtggttg cggatcagaa
     3421 ggccaatctg ctgggttagg tagtcgcgga acaggtccgg ccgggtgatc gtcgccgcat
     3481 aggtgccggg cagcgtgaca tggccgaagg ccagccggga atcggcctgc tcgtggctcg
     3541 aggtcgtcag ccggacctcg ggatagaagg cgcggaacct tgccgccggc ggatgccccc
     3601 cccgcagcgt gcctacgaaa cggtccagca gccagcccgt ggcacggtcg tgaagctcga
     3661 tcaggcgggc gacggcggcc tggggatcgt caaaatattc gcgctcgacc ggctcgggcg
     3721 tctcgacggg cagcaggcgg gagagctggt ccatgggcgg gctcctttag ccccggacag
     3781 tggcagcggg tggtggcact ggcaagacgg cggcggcagc cctatctcgg ggggcatgga
     3841 catctctatt ctcgatctcg cgccggtgcc cgagggctcg gacacaaagg cggccatcgc
     3901 cagcagcgtg acgctggcac gcgcggcgga agcccagggc tacaagcggt tctggctggc
     3961 cgagcaccac aacatgccgg gcatcgccag cgcagcgaca gccgtgctga tcggccatat
     4021 cgccgatcac accaaggaca tccgcgtcgg cgcgggcggg atcatgctgc cgaaccacgc
     4081 gccgctggcg gtggccgagg ccttcgggac gctggccacc atccatgggc cgcgcatcga
     4141 cctcggcctt ggccgcgcgc ccggcggcga cggggcggtg atgcacgcgc tgcggcgggg
     4201 ccagtcccgc aacgaggatt tccccaacga cgtggtggaa ctgctgcatt acctcggccc
     4261 cgaacgcccc ggcgtggcgg tggctgccca tcccgggcag gggacgaacg tgccggtctg
     4321 gattctcggc tcgtcgcttt acggggcaag cctcgcggct gcgctggggc tgccttacgc
     4381 tttcgcctcg catttcgcgc ccgacgcgct ggacgacgcg gtagcgcttt accgcgaccg
     4441 cttccagcca gggccctggg gcgacaaacc gcgcttcatg ctggccgcga acctgatcgc
     4501 ggcggacacg gacgcggaag cgcggcggct gcggaccagt tcgcagatcc agttcttccg
     4561 gctgcggacc ggcaatcccg gcttgctgcc cgcgccggtg gatgatcttg atgcggtcgt
     4621 gcccgcgcaa taccagtcga tggtggaccg ggtgctgagc gtcagcgccg tcggcgcccc
     4681 cgacaccgtc aaggcgcaga tcgacgcgat ggtcgcccgc tacaagccgg acgagctgat
     4741 cctgaccggc aacatctggg acccggcggc gcgcgaaaaa tccttcgcca tcggggccga
     4801 ggtgctggga ctcacccgcg catgacctcg cgcctggtgg tgctgggcca tggctattcg
     4861 gccggcttcc tgacccggcg gctggtgccg cagggctgga ccgtcaccgg caccacccgc
     4921 gacaatgctt cacgtgtcac gctggcaggc gccacgcccc tgcgctggcc cggcgagggg
     4981 gacgcggtgc gggccgagat cgcccgcgcc gacgcgatcc tgatcagcgc cgggccggag
     5041 gccggggaat gcccggcgct gcgcgaattc ggcacagcca tcgcggacag ccgcgcccgc
     5101 tggttcggct atctctccac caccggagtt tatggcgacc gacagggcgg ctgggtggac
     5161 gagacctcag acctcgcgcc ctcgacccgc cggggccgcg accgcgtggc ggcggaagcc
     5221 gggtggcagg cgctggccgc agcgcacggg ttgccgctac acatcttccg ccttgccggc
     5281 atctacggcc ccggacgcgg ccctttcgag aaggtccgca acggcaccgc ccgacgcatc
     5341 atcaagccgg ggcaggtgtt ttcccgcatc catgccgagg acatcgcgca gaccctcgcg
     5401 gcctcgatcg cccggccctc acccggcgcg atttacaacc tctgcgacga tgaccccgcc
     5461 ccgcccgagg atgtgctgga acatgcagcc catctgctgg gcctgccccc gccgcccgcc
     5521 gaggatttca cgaccgccga gatgacgccg atggctcgca gcttctatgc cgaaagcaag
     5581 cgcgtctcga acgcgcggat caagcgcgac ctcggcatcc gcctgatcca cccggactat
     5641 cgcagcgggc tggccgcgat cctggcggaa gaatccgtca gggcgtgatc cggcagcagc
     5701 cgttctccat ccgcgaggcc tggtccgcgc cctcgaacag cagcgtggcc gacagcccga
     5761 aggcgcgatc cgacatgccg tcgctgcatt gggcgggggt cagcaccacc gtcagtcggc
     5821 cctgcgcgtc gcccgcgatg atgctgcggg cgggctcgcg ccgggcgggg ttgtccacca
     5881 ccacgcggcg ctgcaggggg cgcgagagtt cgggcgtctc gtagacgatg ttggcgccga
     5941 cctgccgcag cgaccagaag ggctcggtcc cgaggcagtt cagcgtggcc ggaatttcgc
     6001 ccggcttcca gacatcgggc cgttcctgaa gatagcgcat gttgacccag cccgagcgct
     6061 cgaaggtgtt gacccgcgcc cagccggacc gtgtctcgat cacctcgacc cccgttgcgt
     6121 catgcggcag ttccgacagg atcgaggagg aggcgtccgg catcgcccgg atattaagca
     6181 cgtcgttcga cttgaccccc gtcacgtcgt agagcgtcgg cagcatggac tgcgcggcgg
     6241 cgggaccggc gagggcaagg gtcagggcaa gggcggcaag acgcatcggg aacctcgggg
     6301 cttgtcagac aacggccccg aaaagatgcc cgatcaccga ggtcaccgcc atcgcgaatg
     6361 aaccccacag caacacacgc acgagagcag ggcggagagg cgcacccccc gcccatgccc
     6421 ccagcatgcc caaagcggcc agcgcgatca gcgtcaccgc cagaaccacc ggcacgatca
     6481 gccccaaggg tgtcagcagc gccgcgagat agggcacccc gcccgccacg gtgaaggtcg
     6541 cgcccgaggc catcgcggcc tgcatgggat ccgccgaaag ctcctcggtc agacccagtt
     6601 catcgcgcag gtgggcgccc agcgcgtcat gctcggtcag ctcgcaggcg accagccggg
     6661 cggtgtcggg ggcgaggccg cgcgattcgt agatcaggat cagttcctcc agctcgatct
     6721 cgggctggtg gtgcagtgcc tgtcgctcgc ggtggatgtc ggcggcctcg atgtcggact
     6781 gggaactgac gctgacatat tcccccgccg ccatcgacag cgcgcccgcg gccaaccctg
     6841 cgccgcccgc gatcatcacc gcctgcggat cgcccgaggc cgtcgccacg cccacgacca
     6901 gcgagccgat cgacacgatc ccgtcattcg cccccaagac agccgcccgc agccagttcg
     6961 agcgggtgat gtaatgcggg tcgtcaggat gggcatcggg gtgggtgttg cgggtcatgg
     7021 ctgtgttcca gtcgcgcagg ccatgcatgg ccaagccgct cggcagtcga ataggcgcgg
     7081 ccggcgcggc ccgtcaatcg acggagaagt aatcctcgtc gatgcggcgg ataacatagg
     7141 tcgcgctggt gcgcaccccc acgccgtggt cgatcatcaa ccgggccagc cgcgccccgt
     7201 cgatcagcac gacgcgctgc tcgatcccgc gcacatagcc ccatgcctcc ttggtgaagg
     7261 aggaggtcgt gacgaacacg ccctttcgtg ccctcgcccc gatcagcgag ccgacgaagc
     7321 cctgaagcgc ggggcggcca atggcattct cgggcttgta gcgcttggcc tggatataga
     7381 cagcgtcgag gcccagcttg tcctcgttga tgattccatc aatgccgccg tcgccggact
     7441 tgccgatggc acgacccatc tccgcccgac cgctgccata gcccatggcg atcaacaggt
     7501 cgacgatgac ctgctcgaaa cgggcaggcg tgacagcgag gagttgttcc agcagttcct
     7561 cggccaacgc gtcctgcagg gcggcatggg ccgagtcgat cagttcctgc ggggtctcgg
     7621 tcgtgtcctg tggttcggaa gcaccgaaca cgggcacttc tggcgcttcc tttgatcgtc
     7681 ctgccaagta tgtcagccat tccagaaagt ccgggtaggt tctgagcgtg ttcttgtcga
     7741 tcttggtcgg attgctgtcc agcagcgcct ttcccgcagg agtgatccgg taatggcccc
     7801 gtttgatggg ttccactagg ccggcgtgca tcatgtagtt ccgcgcccaa tgagcacggt
     7861 tcgacatata gctctgagtt ccactgggaa gcagcatttc catctgggtg tcggaaagca
     7921 aaaactgttt ctgcagtccg ggaagggagt cggcgatcga ctgctttccc tcgccgatca
     7981 tgcgaagaat tggcaacatt aactcttcgt attttggcag cccctctccc ctcacgcccg
     8041 ccgccccagc gcggcgaccc ccagcacctc cagcaccttt gcctcgatct ggggcgcctc
     8101 catggcagcc gcgcgataca tcgcctcggg actggcgtgg tcgatgaagg tgtcgggcag
     8161 gaccatgctg cggaagcgga agccgcggtc gaagacgcct tcttccgcca acagttgggc
     8221 cacatggctg ccgaagccgc cgatggcgcc ctcctcgatg gtgatcagcg cctcgtgttc
     8281 gcgcaccagc cgcaggatca ggtcgcggtc cagcggcttg gcgaagcggg cgtccgccac
     8341 ggtgggggcg aggccgcgtg ccataagcga ttcgcgggcg cgcaggacct cggagagcct
     8401 cgtgccgaag gacaggatgg cgacgcgggc gccttccgcc acgatgcggc cgcggccgat
     8461 ttccagcggc tcggggcgct cgggcagttc gacgccggtg ccctcgccgc gcgggaagcg
     8521 gaaggccgag gggcggtcgt ccagcgcgac agcggtggcg accatgcgga ccagttcggc
     8581 ctcatcggcg gcggccatga cgacgaagcc gggcaggttc gcaaggaagc ctacgtcata
     8641 ggcacccgca tgggtcgcgc catcggcgcc gaccagcccg gcgcggtcga tggcgaagcg
     8701 cacgggcagg cgctggatcg ccacgtcatg gacaacttgg tcatagccgc gctgcaggaa
     8761 ggtcgaatag atcgcgcaga agggccgcat cccccccgcc gcaagcccgg ccgagaaggt
     8821 cacggcgtgc tgttccgcga tccccacgtc gaagcagcgg cgggggaagc ggtcggcaaa
     8881 caggttcagt cccgtcccgt ccggcatggc ggcggtgatc gccacgatgc ggtcgtcccg
     8941 ctcggcctgg gcgatcaggg acttggcgaa gacgctggta tagctggggg cgttggactt
     9001 ggccttggcc tgctcgcccg tgatgacgtc gaacttggcg cgggcatggc cgcggtcggc
     9061 ggcgttctcg gccggggcgt agcctttccc cttcttcgtc accgcatgga tcaacaccgg
     9121 cccgtccgcc cgcgccttga ccgtcctgag cagcggcaga agctggtcga ggtcgtggcc
     9181 gtccaccggg ccgacgtaag agaagcccag ttcctcgaac agggtgccgc cgatggtgat
     9241 gcccttcagc atctccttgg cgcggcgggc gccctcctgc atgggcggcg gcagcaggct
     9301 gaccgcccct ttggcggcgg ccttcagttc ctggaacggc ccttgggtgt aaagccgggt
     9361 caggtagcta gacatcgccc cggtcggcgg ggcgatcgac atctcgttgt cgttcaggat
     9421 cacgaacaga cgggtgccca tgtggcccgc gttgttcatc gcctcgaagg ccatgccgcc
     9481 gctcatggcg ccgtccccga tcacggcgat ggcgtcgccc ggatcgccgc cgaggtcacg
     9541 cgccgcggca aagcccagcg ccgcgctgat cgaggtcgag gaatggcccg ccccgaaggg
     9601 gtcatgcggg ctttccgacc gcttggtgaa gcccgacagc cctccttcca tccgcaggct
     9661 gcggatgcgg tcgcgccggc cggtcaggat cttgtgggga tagcactggt ggcccacgtc
     9721 ccagacgatc ttgtcgcgcg ggctgtccca gaccgcgtgc agcgccacgg tcagttcgac
     9781 cacgccaagc cccgcgccca gatggccgcc agtcacgctg acggcgctga tcgtttccgc
     9841 tcgcaactcg tcggccagct ggtgcagctg gcggtcgctc agcgccttga ggtcggcggg
     9901 agaggcgacg cggtcgagga tcggggttgc gggacgcgag gtcgtgtcgg tcatgggctg
     9961 gccccttccg ggcgggcgga ccccccggag gcggtcggtc tcaggtcttg cggtggataa
    10021 cgaaacgcgc cagcgcccgc aagtttccgg ccctgtcgcc ataggagtcg agcgcggcct
    10081 cggcccgcac taccatttgg gtcgcccgcg cccgcgcttc ctccagcccc agcagggaaa
    10141 caaaggtggc cttgcccgcc gcctgatcct tgccggtgcg cttgccggtc tgttccacgc
    10201 tggcggtcac gtccagaatg tcgtcggcga tctggaaggc cagcccgagg tagtgggcat
    10261 agtcctgcaa aggcgcggga tcggtgccgc cgatgatcgc cccggccgac gcggcaaagc
    10321 ggatcagcgc gccggtcttg gcgtgctgca gcgcctctat ggcgggcagg tccagcggag
    10381 tgcccgccgt ctcggccgcg atgtcctgcg cctgtcccca gaccatgccc cgcgcgcctg
    10441 aggcctcggc cagccgcgcc accagcgcaa tgcgcgcctc ggccgggccg atcaccgggt
    10501 cggagagcat tgcgaaggcc tgcgtctgca gcgcgtcgcc ggcaaggatc gccgtcgcct
    10561 cgatccagcg gacgtggcag gtgggctggc cccggcgcag gtcgtcgtca tccatcgccg
    10621 gcaggtcgtc gtggatcagg ctgtaggcgt gcagcagttc caccgccacg gcgaccggca
    10681 tggcgctgag gtcctcgacg ccgaacagcc gcgccgattc cagcaccagg aaggcgcgga
    10741 tgcgcttgcc gccattggtg gcataacgca tcgcgtcggt caggtcgccc gacggcaggt
    10801 ccgccagcgc agcctcgatg gcgctcgctg tggcgcgctg cgcctcctcc agcctttggt
    10861 gcatccttac agcccttcga ccggggcggt cccgctgggc tctccattgg cggcaagcat
    10921 gatcttctcg acccgctcct cggcctggcg caaccggcgc tcgcaatggg cacgcagctt
    10981 tgcgccgcgt tcgtaaaggg cgatggactg ttccagcgtc gcctcgccat gttccagctt
    11041 gccgacgacc gattcgagtt ccttcatcgc gtcctcgaag gacatctggt cgatttcggc
    11101 atcggtcatg ggccggttcc ttcaagcgcg gtgacatggg cgcgggcgga tcggcccagc
    11161 gcggccagat catagccccc ttccaggacc gagaccaccg gggccgcgcc tgccgcgtcg
    11221 cagatcatgc gggtgatcgc ggcaaagtca tcgtcctccc attcgagcgc ggcgaggggg
    11281 tcggccgcat gggcgtcgaa gcccgccgag atgatgacaa gctgcggcgc atgggcctgc
    11341 aggcgatcca tgatctgccg ccatgcggcc cgcgcctgcg ctccgcccga gccgggcggc
    11401 agcgggacat tcatcacctg cccatgcgcg ccggtctcgc ttgcgcgccc ggtgccggga
    11461 taaagcggca tctggtgggt cgaggcgaag aaggcgcggg attcgtccca cagcaggtcc
    11521 tgcgtgccat tgccgtggtg aacgtcgaag tccagcaccg ctacccggtc cagcccgtga
    11581 tgatccagcg cgcgcatcgc cgcgatggcg gcggtgccga gcaggcagaa gcccatcggc
    11641 gtctcgcgtt ccgcatgatg ccccggcggg cgcatggcga cgaaggcgcg gctgtcctct
    11701 ccgccaagca ccgcatccac cgccgcgcag gccgcgccga cggcccgcat cgcggcctcc
    11761 atgctgcccg gcgacagcca ggtgtccggg tccagcgcca cctgtccctg cgccggcacc
    11821 gcggccttca gccgggcaag gtagcgctcg gggtggcagc gcagcatgtc ggcctcagcg
    11881 gccagcggcg cctcgcggcg atcgagcttc agatccgcca gcccgtccag caccgccttg
    11941 tggcgggcga cctgctctgg gtggccggac ggggtgaggt gccgttcgga ggcagaatgc
    12001 gtgtagagga tcgtcatgcc cgcaagctaa tggcaaccgc tgcagaagcg caatcgcaag
    12061 cattacagtc cggcgccgcg cctgctgcac ggttgcatgg gtatttggac cagaaagatg
    12121 tcactcgtgc gggccaaaga agaagacttc tttctggtcc aaatacccat gcggcgcttc
    12181 agccgggaat atctgctcca atcggtgcgc ggctcaggcg gcgaggcggg cgccgtcgtg
    12241 gccggtgatc gtcacctcga ccagtgcgcc ctcgggcagg tcatgggcaa aggaaacctc
    12301 ggtaaactgc tcggtgcggc cgatgcgagg tccctcggtc agaacacggt gagaccgacc
    12361 gacctgtgcc tgtaggtgcg cggccagcgc agccttgccc acggcgcgca ggcgcgcggc
    12421 gcggtccttg atcgcagggc cgggcacgcg cggcatccgc gcggccgggg tgcccgtgcg
    12481 cgcgctgtag gggaagacgt gcaggaaggt caggccgcag tcctgcacca gcttcaccga
    12541 gttctcgaaa tgcgcctcgg attcggtggg aaagcccgca atgatgtcgg cgccgaagac
    12601 gatgccggga cgcatgcggc gggcttcctc gcagaaggcg atggcatcat cgcgcctgtg
    12661 gcggcgcttc atgcgcttga ggatcaggtc gtcgccatgc tgaagggaca gatgcagatg
    12721 cggcatcagg cgcggctcgg tggcgatcgc ctccatcagc tcggggtcgg cctcgatcga
    12781 atcgatggaa ctgatccgca ggcgtggcag gtcgggcacc atccgcagga tgcgccgcac
    12841 gaggttgccc agccggggct ggcccggcag gtcagcgccc cagcttgtca ggtccacgcc
    12901 agtcagcacg acctcgttga agccgcggtc gcgcaaccgt ttgatctggt ccacgaccac
    12961 gcccgccggg acagaccgag agtttccccg gccatagggg atgatgcaga aggtgcagcg
    13021 gtggtcgcag ccgttctgga cctgcacata ggcccggtgg cggccgaagc cgtcgatcag
    13081 gtggcccgcc gtttcccgca ccgacatgat gtcgtctacc atcacccgct cggtgccata
    13141 gtcgggcgcg gcgaggctgg cccaggtcgc gggctgcatc ttctcgtggt tgcctatgac
    13201 gcgggcgacc tcgggcatgg cggcgaaggt gtcgggttcc gtttgcgccg cgcagccggt
    13261 gacgatgatt ggcgcgccgg ggttttctcg cgacaggcgg cggatttcct ggcgggcctt
    13321 gcggacggcc tcggcggtga cggcgcaggt gttgacgatc accgcgccgt tcaggccggc
    13381 ctcgcgggcc atctcggcca tcgcctcgga ttcataggcg ttcagccggc agcccagcgt
    13441 ggcgaagatc gggggagcgg tcatgtcgcg gccagccatt cgggcgacag gacaccctcg
    13501 aagacccgcg ccaccggtcc ggtcatccac accccgtcct cgcgccagtc cacgaccagc
    13561 gtgccgccgt cgaggtccag caccacccgc cgccccgtca gcccgcgccg atgcgccgcg
    13621 accgccgtgg cgcaggcccc cgacccgcag gcgagcgtca cgccggcgcc gcgttcccag
    13681 acccgcatcc gcaggcggtc gggggcggtc agcgaggcga actcgacatt cgtgcgctcg
    13741 gggaacagtg catcatgctc gatccggggg ccgatcgcgg tcaggtccac cgcctcggca
    13801 tcggggacga agaagacgca atgcggattg cccatgccga ccgccgcggg gccgccgtcc
    13861 agcgggagcc gctcggtgtc catctcgcgc gccagcggca cctcgtccca ggcaagctgg
    13921 ggatgaccca tgttgacatg gacctggccg tcccgacgtt ccgcttccag catcccgcgc
    13981 agcgtggaaa agcgcacccg gtcccgcccc ggatcacgca tcatcaggtc ggccacgcag
    14041 cgcgaggcgt tgccgcaggc cccggccccg gacccgtcgg cgttccagaa ctccagccgg
    14101 tagtccgccg catcgtcggg gcagatctcg gccagctggt cgaagcccac gccccggttg
    14161 cggtccccca gcgcccgcgc cagcgcaggc gtcacccgcc gctgcggggc gccgcgcgag
    14221 tcgatgatga cgaagtcgtt gcccgccccg tgcatcttga cgaagccgag gccgcccggg
    14281 ttttcctgtt ccatcgcggc gatatacgcg cacatccgcg attgtgccag atgcgcagcg
    14341 atttggcctt gacccccgcc aaacgcatcc gtaaggaaac gccctgtgtt gggcccatag
    14401 ctcagttggt agagcaactg acttttaatc agtgggtcac aggttcgaat cctgttgggc
    14461 tcaccactga actttctgaa atcgttggaa ataatcggct cgccttaagg tggcctgtcc
    14521 gacgtccgag agcgtccgaa tttggacgtc ggacgcgggg tcccgcggac tgccttgatt
    14581 ttcgaatcct gttgggctca ccactgaaat cccctgcgac atcgacgtgc gccagccttc
    14641 cggcaccatc cggggcggct tgcgcttttg tgagtccgtt tgtccgggac aggtgattga
    14701 cgccccggaa ctgtccctgt agctcggcgt caaagcagtt tctggcaggc tgaggccgtt
    14761 ttccgacctt gcggatacgc aaggggcggg catagtccgg cccggaggtg cgcatcgtgc
    14821 ctgcccggtg gcatccccgc gatggccttc ggaaagcgct tgcggcggga ccgtttccct
    14881 gcgccgcgcc cagaacccgg cccgcgaggt cgatcaaatc gcgcggcgct gcaagccgca
    14941 accggacgaa gaaaggcaag ccgccgacga atgctcgccc agaacctcct tctcctgctt
    15001 gcggtgctgc ccttcgcggg cgcgatcctg gccgtcacca tgcccgtcac cgcccgcaac
    15061 gccgaggtgg tgctggcggg cggcgtgatg atcgcggggc tgctggcgct gttcgcggtc
    15121 atgggggatg tggccgatgc gcaggctgtg gcccgcagca tcgaatgggc gccctcgctg
    15181 gggcttgacc tgacgctgcg gctggacggc ttttcctggc tgatgctgct tctggtctac
    15241 ggcatcgggc tgctggtcgt catctacgcc cgctactacc tgtcgccctc ggacccggtg
    15301 ccgcggttct acggcttcct gctggctttc gcggggtcga tggtggggat gctgatttcc
    15361 ggcaacatca tcctgatggt ggtgttctgg gaactgacca gcctcttttc cttcctgctg
    15421 atcggctact ggaaccacaa tgccgccgcc cgcgacgggg cgaggacggc gctgatcgtg
    15481 accggcgggg gcggcctctg cctgctgatg gcgatgatcc tgctgggtca tgccgccggc
    15541 agctaccacc tggacgacgt gctggccgcg ggcgaccggg tgcgcgagca tccctggtat
    15601 ctgtggatct tggggctgtt cctgatcggg gccttcacca agtcggcgca gtttccgttc
    15661 catttctggc ttccgaacgc gatggcggcg ccgacgccgg tttcggccta tctgcattcc
    15721 gcgacaatgg tgaaggcggg ggtgttcatc cttgtccgct tctcgcccgt gctgggcggc
    15781 accgatgcct ggttctggat cgtcgcgggc accgggatgc tgaccttgct gctgggcgcg
    15841 gtgatcgcac tgtggcgcaa cgacctgaag gggctgctgg cctattcgac gatcagtcac
    15901 ctcgggctga tcaccgcgct gtgcggcatg ggcagcggcg gcgcgatcgt ggccgcgatc
    15961 ttccacatca tgaaccacgc ggtcttcaag gcctcgctgt tcatggccgc gggcatcatc
    16021 gaccacgaga ccggcacccg cgacatgcgc cgcctcagcg ggctgcgcca ttcgatgccg
    16081 cgcaccgcgg cgctggccat cgtcgccgcc gccgcgatgg ggggcgtgcc gctgctgaac
    16141 ggctttctgt cgaaggagat gttcttcgcc gaggccgccg actggcacaa cggcacatgg
    16201 ctggacgcgg ccctgcccta tatcgccacc atcgccagca ccttcagcgt ggcctattcg
    16261 ctgcgcttca tcgtcaccgt cttcttcggt cccccagcca ccgacctgcc gaaggaaccg
    16321 cacgagccgc cggcctggat gcgccgcccg gtcgagttcc tggtcgccat cgtcctgctg
    16381 gtgggcctgt ggcccgcagc cctgatcggc ggtccgctgc acgcgggcgt gctggcggtg
    16441 ctgggcgaga acgcgcccta ttacagcctg tcactgtggc acggcttcaa cgtcgccctg
    16501 acaatgagca tcgttgccct ggtggcgggc acgatcctgt atttcctgat ggcgcggcgt
    16561 ctgtccgagg cgaacgaggc cccggccttc ctgtcgctgg tccgcggcca gcaggtcttc
    16621 gaccgcctga tgctggtgct gacccgcaag tggcccgcct gggcctatcg ccgggtcggc
    16681 agcccgcgcc tgcaggtgca gttgcggctg ctggtgctgc tcagcctcgg ggcgacggcg
    16741 gcgacgctgt ggggcgctgc gcggctggtg cccgaaggat tgctgcagaa cttcgacgcg
    16801 accttcgcgc tgctgtggat gggggggatc gcctgtgcca tcggggcggc gatccaggcc
    16861 aagtatcacc gctttgccgc gctggcgctg ctgggcagcg cggggctggt gacggccgtg
    16921 acctttgcct ggttctcggc ccccgacctc gcggtgacgc agctcctggt cgagatcatg
    16981 acaaccgtgc tgctgctgct ggggctgcgc tggctgccca agcggatgaa gctgatcgag
    17041 ggcgacgacc gcttcaccgc ccgcaggcgg cggggcatcg acttcgtggt ggcgaccgtc
    17101 tgcggcgcgg gcgtcgcggc catcgccttt gcggtgatga ccacgcccgc cgggctgacc
    17161 atcggcgact ggttccgccg caattcctat gccgagggtg gcgggacgaa cgccgtcaac
    17221 gtgatcctgg tggacttccg cgcctttgac accctgggcg agatcaccgt gctggggatc
    17281 gtggcgctga cctgctacgc gctgctgcgc cgtttccgcc cggcgccgga aagcgtggcg
    17341 ctgccctcgc agcagacctt caacgaactg ccccccctcg accccgagcg cgagcgcgag
    17401 gcggaacgcg agcccacgcg gcacgacgtg atgatgatga tcccctcggt catcatgcag
    17461 tggatgttcc cgctgaccgt ggcgctgtcg atgtatctgt tcctgcgcgg ccatgacctg
    17521 ccgggcggcg gcttcgcggg cggcgtcgcc ttcgccatcg ggctgctgct gcaatacctg
    17581 gcaagggacg tgcgctgggt ggaaagccgc atcaccatcc tgccggtgcg ctggatcggg
    17641 ctggggctgg tgatcgcggt ggcgaccggc atgggctcgt tcctgttcgg ctatccgttc
    17701 ctgacggccc atgcccagta tgtcaccctg ccggtgatcg ggcaggtgcc ggcggcgacg
    17761 gcgctggtct tcgacctcgg cgtcttcgcc acggtggtgg gggcggccgt gctgatccag
    17821 atcgccatcg cccaccagtc gctgcgctcg tcccgcctgc gggcgcgcga gaccgcagcc
    17881 gacgccgacc cgaaggagga gcaggaaaac cgccacgagg aacaggaaca acagcgggag
    17941 ggcgtgtgat ggaactgacc ttgtcccttg gcatcggcgt gctggtcgca tccggcgtct
    18001 ggctgaccct gcggccgcgc accttccagg tcatcgtcgg cctctgcctg ctgtcctatg
    18061 gcgtcaacct gttcatcttc gccatgggcc ggctggtcac aggggctgcc ccgatcatgc
    18121 ccaagggcgg cttcgtcaac cccgacgcct atgccgatcc ggtgccgcag gccctggtgc
    18181 tgaccgccat cgtcatcagc ttcgccacca ccgccctgtt ccttgtcgtc atcatggcct
    18241 cgcgcggctt gaccggcacc gaccacgtcg acgggaagga gcgcggccag tgatctctcc
    18301 ggcccatatc gtcgtcctgc cgatcctgat cccgctgctc gcgggggcga tcatgctgat
    18361 gtatgacgaa cgccagcggc ggctgaagct ggggatcggc atcctgtcct gcgtgctgca
    18421 gctggccgtc gccatcgcgc tggtggaccg cgccggcggc tcggccgaca tgggacgcaa
    18481 catggtcacc ctgtatctgc tgggcgactg gccctcgccc ttcggcatcg tgctggtgct
    18541 ggaccggctg gcggcggtca tgctgttgct cggctccatc atcgccctgc cggcgctgct
    18601 ttatgcgggc gcgggatggc accggaacgg gcagcatttc tcgcccctgt tccagttcct
    18661 gctgatgggg gtcaacgggt cgttcctgac cggcgacctg ttcaacctgt tcgtcttctt
    18721 cgaggtgatg ctggcggcct cctacgggct gctgcttcac ggcacgggcc gcgtccgggt
    18781 ggcggcgggg ctgcattaca tcgccgtcaa cctcgtcgcg gcgatgctgt tcctgctggg
    18841 cgtctcgctg atctacgggg ccaccggcac gctgaacatg gccgatctcg cgtcccgcat
    18901 cccgcggctg tccgaggccg accgccccat ggtccatgcg gcggcggcgc tgctgtcggg
    18961 cgccttcctt gtcaaggcgg cgatgtggcc gctgtgcttc tggctgccca atgcctacgg
    19021 cgcggcctcg cccccggtcg cggcgatctt ctcgctgctg acaaaggtcg gggcctatgt
    19081 ggtgatccgc ctcggcctgc tgctgttcgg cgcgggggca ggcgaatctg cgggcttcgg
    19141 cgccaacgtg ctggcggcgg gcggcatggc caccatgatc ttcggcgcgc tgggggtgct
    19201 gcaggcgcag gatctgggca ggatgaccgg caacctggtg ctggtgtcct cggggacgct
    19261 gctggcggtc gtcgggctgg cgcagatcta cgacgacgcg ccgatgctga cggcggcgct
    19321 ttactacatg atcgcctcga ccatcgccat cgcggcgctg ttcctgctgg ccgaacccat
    19381 cggccgcaag gaaggcggca tcgccgggct tctggcgatc accgccgagg cttatgccga
    19441 tcccgaggaa gagatcgacg agcccaccga cgagggccgg gccatccccg gcgccaccgc
    19501 gctgctgggc gtggccttcc ttgcctgtgt gctggtggtg gcggggctgc cgccgcttgc
    19561 gggctttctc ggcaagttcg ggatgctgtc gggcgcggtc gagcgcgcca aggtcctgcc
    19621 cggcatgtgg ggccactggg ccttcgtggt cctgctgatc gtcaccggct tctgcgcgct
    19681 ggtggcgatg gtccgctggg gcatccagag cctctgggcc aacaccgagg aaccgccgct
    19741 gccgatgctt gagatcgtgc cgatcctgat gctggtggcg acggtcgtgc ttctgtcgat
    19801 ccgggcggaa ccggcattgc gctatctcga ccgcaccgcc gacgcgctga cccagaacca
    19861 agtctatatc gggggggtgc tgaccgcacc gccggtgggg tctgacgatc catgaccctg
    19921 ttcccccatc ccatcgtcac cgtcgtcctg accatcctgt ggatggtgct gaccagcttc
    19981 accccgggac agtttgtgct gggcgtgatc gcgggcatcc tcggcgggct cgcctatcgc
    20041 cgcctcacgc ccgagcggat catggtccgc cggccccgcc agatcatccg gctgttcttc
    20101 cgcgtgggcg gcgacatcat ccgctcgaac atcgcggtgg cggggctgat cctgacgcag
    20161 ggacggggcg gccggcgccg cgccggcttt gtccccatcc cgctggacat gaccagcccg
    20221 aacgggcttg cggtgctggc gatcatcgtg accgcgacgc ccggcaccgc ctggatcgaa
    20281 tacgaaccgc gcaacggcct gctgctgctg catgtcttcg accttctgga cgaggatgac
    20341 tgggtccata ccatcaagtc ccgctacgag tccctgctga tggagatctt cgaatgagcg
    20401 caacgatcct gtccgtcgtc ctcacctttt cccagatctg cctggtgatc tcggtggtgc
    20461 tttcggtgct gcgggcgctg cgcggcccgc gggcgcagga ccgggtgctg gggctggaca
    20521 ccatgtacat gtgcgccatg ctgctgctgg tcgtcaccgg gatgcagcag ggcaccatct
    20581 accagttcga ggccgcgctg gtcatcggca ccctgggctt cgtcgccacc gccgccatgg
    20641 ccaagttcct gatgcggggc gaggtgatcg aatgagccat ctggaccaga tccctcctgt
    20701 cattgccttc ctgatctcgg gcttcgttct tctgggcacg atcctgacgc ttctgggcac
    20761 catcgggctg atccggctgg gcagcttcta cgaacggctg cacgccccga ccctggggac
    20821 aagctggggc gcggcgggca tcctgatcgg ctcgatgctg atgt
//
