LOCUS       NZ_CP067225            22152 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Paracoccus sp. MC1862 chromosome, complete genome.
ACCESSION   NZ_CP067225
VERSION     NZ_CP067225.1
KEYWORDS    RefSeq.
SOURCE      Paracoccus sp. MC1862
  ORGANISM  Paracoccus sp. MC1862
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Paracoccaceae; Paracoccus.
REFERENCE   1  (bases 1 to 3307010)
  AUTHORS   Mingchao,X.
  TITLE     Paracoccus sp.MC1862
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3307010)
  AUTHORS   Mingchao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) Chinese Center for Disease Control and
            Prevention, National Institute for Communicable Disease Control and
            Prevention, Changping, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. HGAP 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 282.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016617715.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:33:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,607
            CDSs (total)                      :: 3,551
            Genes (coding)                    :: 3,394
            CDSs (with protein)               :: 3,394
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 65 of 157
            Pseudo Genes (incomplete)         :: 116 of 157
            Pseudo Genes (internal stop)      :: 29 of 157
            Pseudo Genes (multiple problems)  :: 44 of 157
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:42:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1678632
            Orig. end                         :: 1700784
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067225.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22152
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="3"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22152
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22152
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12152](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12152)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(696..1793)
                     /locus_tag="JGR78_RS08360"
                     /old_locus_tag="JGR78_08360"
     CDS             complement(696..1793)
                     /EC_number="1.1.5.-"
                     /GO_function="GO:0016901 - oxidoreductase activity, acting
                     on the CH-OH group of donors, quinone or similar compound
                     as acceptor [Evidence IEA]"
                     /GO_function="GO:0070968 - pyrroloquinoline quinone binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019607.5"
                     /locus_tag="JGR78_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08360"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_182804240.1"
                     /transl_table=11
                     /translation="MDRRSFLALTLPAAMGAMPAMAQARQPFTVQAVARFDRPWAIGFL
                     PGGWMLVTEKPGRVFLVSQRGEKVPVANVPRVLASGQNGLLDIAASPDFSRSARVFFTY
                     VEPAQGGRLVLARARLTVSGNRAALADLGAVWRQAPGGGGGQPGGIIAFDPRGRHLFLT
                     VGDRMQPASAQDPDQGRGKILRLNLDGSTPRDNPWARQGGIRGQTWTTGHRNPYGLAFA
                     PDGRLWSHEMGPRGGDELNLIRPGANYGWPVVSNGNHYDGRPIPDHATRPDFAGPSLSW
                     APVISPAGLVFHQGAMFPGWNGSALIGALSGQALVRAVVGRDGRAAEAERWNMGARIRD
                     VAVSPEGAVWLIEDGRGGRLLRLTP"
     gene            2096..2827
                     /locus_tag="JGR78_RS08365"
                     /old_locus_tag="JGR78_08365"
     CDS             2096..2827
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007799091.1"
                     /locus_tag="JGR78_RS08365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08365"
                     /product="allophanate hydrolase subunit 1"
                     /protein_id="WP_182791864.1"
                     /transl_table=11
                     /translation="MTTPDWPRIALTGIDGIAVTFAARLTEPANRAALALRAAVEAAGW
                     PEVQETAASLVSAYLRVDPLCDMTPLVARLRALVASRDWTAAPLPEDRKLIRIPTCYDS
                     LHAPQLDEAAELAGLTRPQAIEALATSSLRVLTIGFAPGQPYIGELPPEWDIPRLRELT
                     PRVPVGALTVAIRQLVLFAVEAQTGWRHVGQTAARPFDPAAPQPFLLRPGDALAFPPVD
                     ADRLEALMRDPTGGITIETAP"
     gene            2824..3843
                     /locus_tag="JGR78_RS08370"
                     /old_locus_tag="JGR78_08370"
     CDS             2824..3843
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011539380.1"
                     /locus_tag="JGR78_RS08370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08370"
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="WP_182791863.1"
                     /transl_table=11
                     /translation="MSLLVLSSNPGVTIQDRGRPGWLAQGLSRGGAADPVALAEGAALL
                     GQPDNLAVVELAGAPARFRVTAPARLALTGAPFRAILRDGEERPLDWNAIHLLPAGSEL
                     ALYPIEGGFAYLALGGGIETPLILGARSAHLAAEIGGPLSVGGELPLGPDSGEAADLAL
                     DPLPRFGGGEIRVVESLQTALYPPAEIARFQRSTFRRDARGNRMGVRLTPEGGGFELAG
                     GLSVVSEIVQPGDIQITGDGTPFVLLSECQTTGGYPRIATVLPCDLPRVAQAPPGAALT
                     IRFVTRNEARKAMADHAQALASLRGRVRPRLRDPWAVPDLLGYNLIGGVVSAHEGDGP"
     gene            3840..4616
                     /locus_tag="JGR78_RS08375"
                     /old_locus_tag="JGR78_08375"
     CDS             3840..4616
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011539379.1"
                     /locus_tag="JGR78_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08375"
                     /product="LamB/YcsF family protein"
                     /protein_id="WP_182791862.1"
                     /transl_table=11
                     /translation="MTLHVDLNADMGESFGPWTMGDDAALLEVISSANVACGVHAGDWD
                     VMARTMELAVRNGVGIGAHPGFPDLQGFGRREMQMPLPSAANLIRWQLGAAQAMARAAG
                     GEVRHLKLHGALANMASRDEALATACFEGALSVDPGIILMVLAGTAQQAAAQRLGARVA
                     CEIFADRAYSADATLLDRRLPGAVIHDAAEAAARVVRMVKAGAILPEAGVSIPTRIDTI
                     CLHGDTPGAIHIARRVRGALEEAGIRVARFEGTPLR"
     gene            complement(4725..5147)
                     /locus_tag="JGR78_RS08380"
                     /old_locus_tag="JGR78_08380"
     CDS             complement(4725..5147)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1266: hydrogen
                     peroxide sensitive repressor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007796574.1"
                     /locus_tag="JGR78_RS08380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08380"
                     /product="Fur family transcriptional regulator"
                     /protein_id="WP_182791861.1"
                     /transl_table=11
                     /translation="MSAHTTDFAQALRDAGLRVTQQRMVLLAILMDSADHPNADELLAR
                     ARAVDDSVSLATVYRTLSALEEAGLIRKLTLESEPSRYEITPAAEHDHVVDIDTGEVIE
                     IASDEIARLRREMLERLGFEIVSQHTLIRARRIRKS"
     misc_feature    5203..5218
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.37"
                     /tool="antismash"
     misc_feature    complement(5203..5221)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 25.35"
                     /tool="antismash"
     misc_feature    complement(5206..5221)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.62"
                     /tool="antismash"
     misc_feature    5231..5249
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.17"
                     /tool="antismash"
     misc_feature    complement(5234..5249)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.43"
                     /tool="antismash"
     gene            5282..6193
                     /locus_tag="JGR78_RS08385"
                     /old_locus_tag="JGR78_08385"
     CDS             5282..6193
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018000352.1"
                     /locus_tag="JGR78_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08385"
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="WP_182804237.1"
                     /transl_table=11
                     /translation="MASRKARLLAATMALALTAGAAQAQERMKVATTFTVIADMARNVA
                     GDAAEVVSITKPGAEVHGYEPTPQDIVGAQDADLILWNGLNLERWFEQFLGNLRDVPSA
                     TVSDGIAPMPISSGDYEGRPNPHAWMSPANALIYVDNIAAAMAGVDPANATTYAANAEG
                     YKAELTAALEPLKAQIAEIPEPRRWLVTCEGAFSYLARDFGMKELYLWPINADQMGTPR
                     QVRQVIDGVRENDIPAVFCESTVSQAPAEQVARETGARYGGVLYVDSLSEPDGPVPSYL
                     DLMRVTAQTIADGLTAGIAEQD"
     gene            6197..7075
                     /locus_tag="JGR78_RS08390"
                     /old_locus_tag="JGR78_08390"
     CDS             6197..7075
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013385381.1"
                     /locus_tag="JGR78_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08390"
                     /product="manganese/iron ABC transporter ATP-binding
                     protein"
                     /protein_id="WP_370576405.1"
                     /transl_table=11
                     /translation="MPPMSPAKDPGIVARDVTVTYRNGHTALRHASFEIPQGTVTALVG
                     VNGAGKSTLFKAIMGFVPVASGEIRLLGLTVREALRRNLVAYVPQAEEVDWTFPVLVED
                     VVMMGRYGHMGFLRRPSAKDRAAVDEALARVGMADLRHRQIGELSGGQRKRVFLARALA
                     QDGRVILLDEPFTGVDVGTEDRIIQLLGELRDEGRVMLVSTHNLGSVPEFCDRVVLVKG
                     TVLAHGPTETTFTRENLERAFGGVLRHFTLGGEALHDDDDPRHVTILTDDERPLVRYDN
                     RTQIRERAEDA"
     misc_feature    complement(6240..6255)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            7072..7914
                     /locus_tag="JGR78_RS08395"
                     /old_locus_tag="JGR78_08395"
     CDS             7072..7914
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018303520.1"
                     /locus_tag="JGR78_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08395"
                     /product="metal ABC transporter permease"
                     /protein_id="WP_182791859.1"
                     /transl_table=11
                     /translation="MILLEPFAYGYMTNAMWVSALVGGVCAFLSAYLMLKGWSLIGDAL
                     SHSVVPGVAGAYMLGLPFALGAFISGGLAAAAMLFLSDRSGLKPDVVIGLIFTGFFGLG
                     LFMVSLNPVAISVQTITMGNILAITPGDTVQLAIIGFVSLAVLLAKWKDLMVVFFDEAH
                     ARSIGLRPGLLKGVFFVLLSACVVAAMQTVGAFLVIAMVVTPGATAYLLTDRFPRLIAL
                     SVAIGTATSFLGAYLSYFLDGATGGIIVCLQTLVFLAAFVWAPKHGLLAARARARGAS"
     gene            7911..8744
                     /locus_tag="JGR78_RS08400"
                     /old_locus_tag="JGR78_08400"
     CDS             7911..8744
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002721127.1"
                     /locus_tag="JGR78_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08400"
                     /product="metal ABC transporter permease"
                     /protein_id="WP_305798478.1"
                     /transl_table=11
                     /translation="MIETLLAPFQFGFMQNAFLIALIVSVPTALLSCFLVLKGWALMGD
                     AVSHAVLPGIVLAYVLGLPLILGAFAAGMLTSVATGYLAENSRVKQDTVMGVVFSGMFG
                     LGIVLYTAITSDVHLDHILFGNMLGVQPGDLWTAGLISVFVTAALALKWKDLMLHAFDP
                     AQARASGLRVGLLHYGLLTILSLTIVATLTATGLILAVGLLIAPGAIAFLLARSFGRML
                     VVAVAVCMSGMLAGVYASFFLDSAPAPTIILVLTAGFIAAFLRRQWQMRRAQNAG"
     misc_feature    8752..8764
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            8808..10004
                     /locus_tag="JGR78_RS08405"
                     /old_locus_tag="JGR78_08405"
     CDS             8808..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018000774.1"
                     /locus_tag="JGR78_RS08405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08405"
                     /product="NnrS family protein"
                     /protein_id="WP_182804235.1"
                     /transl_table=11
                     /translation="MATTSPPRRPGGIPRGLADTGPVLFSYGFRPFFLGAGLWAVAAMA
                     LWIAALAGVAEPGGTYGAANWHMHEMLFGFASAVLAGYLMTAVPNWTGRMPVSGPPLMA
                     LAALWLAGRLMLTFPLDAPWLAVAVEALFLPVMAAVFLREIIAGRKWRDLKIVGLVALI
                     ALANIGFHAAVLGGGDPRLAARAAVAGFIALILIVGGRITPSFTRNWLARMKRAARPAP
                     ADRFDTVTVAVSLAALVLWVGWPENQVLMLAALAGAALNLMRLLRWRGWHVTEPMVLAL
                     HGGYLMVALGFAAISAAAAGWMSHAAALHVFAIGAIGGEMLAVMTRASRSHTGAETDAD
                     LTATLSFIAIMLAAVARAAADFAAYDALVILSGLSWIAAFGLFTLGHARLLAATRRSR"
     gene            complement(10001..11131)
                     /gene="pqqE"
                     /locus_tag="JGR78_RS08410"
                     /old_locus_tag="JGR78_08410"
     CDS             complement(10001..11131)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011567421.1"
                     /locus_tag="JGR78_RS08410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08410"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_182804233.1"
                     /sec_met_domain="PF04055 (E-value: 7.8e-24, bitscore: 82.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.1e-06, bitscore: 25.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.2e-10, bitscore: 36.8,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.3e-08, bitscore:
                     32.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVHPTPVPVRQVRPRPDPPLAMLAELTHRCPLSCPYCSNPLEL
                     TARERELTTEQWAGVFRQAADMGVLQLHISGGEPASRPDLVQIVAAAREAGLYTNLITS
                     GIGLTGRRLDELDAAGLDHVQLSVQGVNAGIADTVGGYKGGFDRKMMVAAEIARIGFPL
                     TINAVMHRHNLGDLPQTIALAHDLGARRIEIACVQFQGWALKNRSALQPTREQVDEAKR
                     VVAQARVDYAGRLAIDFVPPDYFADFPKACMNGWGSTGLNVTPEGKVLPCHAAEIILGL
                     TFQNVLTTPLAEIWNDGPAFNAFRGTDWMPDLCQTCERRDIDFGGCRCQAMAIAGDARA
                     TDPVCRRSPHRAALDALIEAETSAPAPAFEYRRMPR"
     gene            complement(11128..11400)
                     /gene="pqqD"
                     /locus_tag="JGR78_RS08415"
                     /old_locus_tag="JGR78_08415"
     CDS             complement(11128..11400)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013963496.1"
                     /locus_tag="JGR78_RS08415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08415"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_182791856.1"
                     /sec_met_domain="PqqD_RRE (E-value: 8.4e-26, bitscore:
                     87.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9e-14, bitscore: 49.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5e-10,
                     bitscore: 36.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPADRPFLPRGVRLHHDRVRDMPVLLGPETALMLDQVGQAVLAE
                     VDGTRDIATISAALAERYAAPVEMIEADVIEFLDDMAARRLVEAT"
     aSDomain        complement(11134..11301)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JGR78_RS08415_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.30E-12"
                     /identifier="RREFam002.1"
                     /label="JGR78_RS08415"
                     /locus_tag="JGR78_RS08415"
                     /protein_end="89"
                     /protein_start="33"
                     /score="36.9"
                     /tool="antismash"
                     /translation="MLDQVGQAVLAEVDGTRDIATISAALAERYAAPVEMIEADVIEFL
                     DDMAARRLVEA"
     aSDomain        complement(11137..11394)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JGR78_RS08415_PqqD_RRE.1"
                     /evalue="7.30E-28"
                     /identifier="RREFam006.1"
                     /label="JGR78_RS08415"
                     /locus_tag="JGR78_RS08415"
                     /protein_end="88"
                     /protein_start="2"
                     /score="87.2"
                     /tool="antismash"
                     /translation="PADRPFLPRGVRLHHDRVRDMPVLLGPETALMLDQVGQAVLAEVD
                     GTRDIATISAALAERYAAPVEMIEADVIEFLDDMAARRLVE"
     gene            complement(11397..12152)
                     /gene="pqqC"
                     /locus_tag="JGR78_RS08420"
                     /old_locus_tag="JGR78_08420"
     CDS             complement(11397..12152)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008887406.1"
                     /locus_tag="JGR78_RS08420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08420"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_182791855.1"
                     /sec_met_domain="TIGR02111 (E-value: 1.1e-116, bitscore:
                     385.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDVTPNRSAFESRLRRIGAERYHDKHPFHTLLHSGGCTIDQVRA
                     WVINRYYYQSRIPMKDAAFMSRVEDHDLRRAWRSRIEDHDGTAEQPGGIWRWLRLAEGV
                     GLDPDYVASTRGVLPATRFAVDAYVRYVREQPLLAAVASSLTELFAPAIHEQRISGLLA
                     HYDFANPQTISYFQHRLTEAPKDVAFGLAWVLDHARTEEQQEMAAAALTFKTDVLWAQL
                     DALHSAYVAPGRIPPGGWQPGEGLLEDAG"
     gene            complement(12149..13030)
                     /gene="pqqB"
                     /locus_tag="JGR78_RS08425"
                     /old_locus_tag="JGR78_08425"
     CDS             complement(12149..13030)
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011047240.1"
                     /locus_tag="JGR78_RS08425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08425"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_182791854.1"
                     /transl_table=11
                     /translation="MKLRILGAAAGGGLPQWNCGCTNCNDARTGRIAAMTQSSVALSSG
                     GQSVVLNASPDIRAQLDACGLHPPDLRGSPVKAVVLTNGDVDHVAGLLNLRESTPFTVH
                     ATSETLQILDQPIFRVLNPDHVDRSTIELEKPFAPLCGLTVTAFAVPGKVALYLEEGEP
                     DTALMGEQTVGLMLEAVGRRLFYIPGCAQVTDELLARLQGADLLLFDGTVWANDEMSRT
                     GTGAKTGARMGHLPMSGEGGSIARLAGLTGTRRIFVHINNTNPVLQPGSAERAEIGKAG
                     WELAHDGMEITL"
     gene            complement(13044..13145)
                     /gene="pqqA"
                     /locus_tag="JGR78_RS08430"
                     /old_locus_tag="JGR78_08430"
     CDS             complement(13044..13145)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011567425.1"
                     /locus_tag="JGR78_RS08430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08430"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_182791853.1"
                     /transl_table=11
                     /translation="MIWSKPKAREVKCGMEINMYGPAEDDRDARDVL"
     misc_feature    complement(13217..13232)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.62"
                     /tool="antismash"
     misc_feature    13246..13259
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            complement(13451..14359)
                     /gene="tsf"
                     /locus_tag="JGR78_RS08435"
                     /old_locus_tag="JGR78_08435"
     CDS             complement(13451..14359)
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tsf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010397333.1"
                     /locus_tag="JGR78_RS08435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08435"
                     /product="translation elongation factor Ts"
                     /protein_id="WP_182791983.1"
                     /transl_table=11
                     /translation="MAISAAMVKELRETTGAGMMDAKKALQETSGDMEAAVDWLRTKGL
                     AKAAKKSGRIAAEGLVAVAVEGGKGVAVEVNSETDFVAKNEAFQSMVRDIAQTGLTVDS
                     TEALAAAQLNGTPVGEVVTEAISRIGENLTLRRMVTVSGENVVSYVHNAAAPNMGKIGV
                     LVALKGDAAKAQEIGKQIAMHIAATNPLSLSESTMDQTLLARELEVQTAKAMEENAASA
                     KPKPEAVIQNNIIPGRMKKFVAENTLLGQSFVINPEVTVEQAAKDAGVEVSAYARVAVG
                     EGIEKKEEDFAAEVAKTLKGA"
     gene            complement(14439..15233)
                     /gene="rpsB"
                     /locus_tag="JGR78_RS08440"
                     /old_locus_tag="JGR78_08440"
     CDS             complement(14439..15233)
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005615477.1"
                     /locus_tag="JGR78_RS08440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08440"
                     /product="30S ribosomal protein S2"
                     /protein_id="WP_182791852.1"
                     /transl_table=11
                     /translation="MALPEYSMRQLLEAGVHYGHQTQRWNPRMAEYIYGDRNGIHILDL
                     TQTVPMLDRALQVIRDTVAKGGRVLFVGTKRQAQRSVADAAEKSAQFYMNHRWLGGTLT
                     NWKTVSQSIQRLKQLDEAMAAGAEGLTKKERLGMEREQAKLQASLGGIRDMGGLPDLLF
                     VIDVNKEDLAVQEANKLGIPVVAIVDTNCSPKGIEHVIPGNDDAARAIALYCDLVARAA
                     LDGMTAQMGAAGVDLGALTDAPVEEFDGIEAEEPAAEQTADA"
     tRNA            15443..15519
                     /anticodon=(pos:1694109..1694111,aa:Arg,seq:ccg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="JGR78_RS08445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="JGR78_08445"
                     /product="tRNA-Arg"
     gene            15443..15519
                     /locus_tag="JGR78_RS08445"
                     /old_locus_tag="JGR78_08445"
     gene            15690..16820
                     /locus_tag="JGR78_RS08450"
                     /old_locus_tag="JGR78_08450"
     CDS             15690..16820
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018000922.1"
                     /locus_tag="JGR78_RS08450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08450"
                     /product="hypothetical protein"
                     /protein_id="WP_182791851.1"
                     /transl_table=11
                     /translation="MDREEQRIRAAGAPAVASDRSYVDWGAILAGAVVAAALSVVFAAF
                     GAGVGLGSISARAGEGLGFGSVILTGLFVVVTMVLSYMAGGYIAGRMRRRVDGASPEES
                     AARDGIHGLAVWGIGTIFGAIMLASAIGSALNAAGSAAATAVEATGSAVGGIAQGVGAV
                     AGGAVQGAGQLVGGAAQALGGAAAGTGATAAASGDGEILPGLPNPIDYVTDNLLRSEAA
                     APDQFSNEAIRSEVGNIMANVVRTGEITDQDRAYLESAIAARTTLSQPEVSARIDQAVG
                     SVQQLRADAQQAVDQAQAEAQRLRDEAAAQAEQLRQQAVEAAETARRAGVLSAFALAAS
                     ALIAAAAAFIGAQKGGKARDEGRIWGGLTHRPLRPR"
     misc_feature    16545..16547
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16937..18757
                     /gene="typA"
                     /locus_tag="JGR78_RS08455"
                     /old_locus_tag="JGR78_08455"
     CDS             16937..18757
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="typA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018301413.1"
                     /locus_tag="JGR78_RS08455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08455"
                     /product="translational GTPase TypA"
                     /protein_id="WP_182791850.1"
                     /transl_table=11
                     /translation="MDIRNIAIIAHVDHGKTTLVDQLLKQSGSFRENQAVAERAMDSND
                     IERERGITILAKATSVEWKGTRINIVDTPGHADFGGEVERILSMVDGVCLLVDAAEGPM
                     PQTKFVTSKALALGLRPIVVLNKVDKPAAEPDQTLNEVFDLFANLGASDEQLDFPHVYA
                     SGVNGWADDSMDGPKKDMGALFDLILRHVPAPSQLARKDEPFQMLAVTLGADPFLGRLL
                     TGRVEAGTARAGDTLKALSRDGERIEQFRVSKILAFRGLTQTAISEAVAGDIVTLAGMS
                     KATVADTLAAPEVETPLQAKPIDPPTISVTFGINDSPLAGRDGNKVQSRVIRERLMREG
                     ETNVAIRVEDTPGGEAFVVSGRGELQMGVLIENMRREGFELSISRPRVIFRDENGERLE
                     PVEEVIIDVDDDYTGVVIEKLTGDRKGDLVEMRPAGHGKTRIVAHVPSRGLIGYQGEFM
                     TDTRGNGVLNRIFHDWAPYKGPIQGRRQGVLISMEDGVSVAYALWNLEERGRLFIGAQE
                     QVYQGMIIGEHSRDNDLEVNPLKGKKLTNVRASGTDEAVRLTPPVRMSLEEAIAYVDDD
                     ELVEVTPKIVRLRKRHLDPHERKRQARTES"
     gene            18826..19470
                     /locus_tag="JGR78_RS08460"
                     /old_locus_tag="JGR78_08460"
     CDS             18826..19470
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024701.5"
                     /locus_tag="JGR78_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08460"
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="WP_182791849.1"
                     /transl_table=11
                     /translation="MKPGESAMDVLLRAACERLVTADPPCCEPDSLASEAGIDPAVARS
                     LLPSTEAVLQNIAESALRRQLDHLTRRLSGLSDQTPAHQLVELGRAYIEWAIENRNDFQ
                     VLNSRMIRGTLDKEEVNRYHNALQHLTLSMLTRARDQGQLRPDMDPMLLSLVSRAFSYG
                     LARLYVDRQLALWEVGDPDEDEYTKATAALEGFADLLLTNWRRDQPAASKA"
     gene            complement(19649..19972)
                     /locus_tag="JGR78_RS08465"
                     /old_locus_tag="JGR78_08465"
     CDS             complement(19649..19972)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013068113.1"
                     /locus_tag="JGR78_RS08465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08465"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_182791848.1"
                     /transl_table=11
                     /translation="MARITYIEWNGTRHEVEVRPGMTVMEGARDNGIPGIEADCGGACA
                     CSTCHVYVAPEWVDRLPPRDPMEADMLDFAWQPDPDRSRLTCQIKVTPELDGLVVQMPE
                     KQI"
     misc_feature    complement(19949..19963)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            complement(20286..21512)
                     /locus_tag="JGR78_RS08470"
                     /old_locus_tag="JGR78_08470"
     CDS             complement(20286..21512)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (74-407). E-value:
                     2.3e-56. Score: 183.4. Matches aSDomain:
                     nrpspksdomains_JGR78_RS08470_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017928791.1"
                     /locus_tag="JGR78_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08470"
                     /product="beta-ketoacyl synthase"
                     /protein_id="WP_182791847.1"
                     /sec_met_domain="t2fas (E-value: 1.1e-122, bitscore: 407.4,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.7e-44, bitscore:
                     149.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPQGPRRVAITGMGTINALGRNVPETLEAMREGRCGIGALDFQ
                     DVERLSVRIGAQVRGWNPEACFNRQQISLYDRFTQFTLLAAKEAVAQSRLNFQGELGLC
                     SGVVLGTAGGGLNTWDKNYRAVYEEGKNRVHPFVVPKLMNNAAASHVSMEFSLRGPAFT
                     VATACASSNHAMGLAFQMVRSGAARVMLSGGSEAMLCFGGIKAWEGLRVMSRDACRPFS
                     ANRNGMVQGEGAGVFVFEDWDHAAARGADILAEVVGFAMSADAQDIVMPSAQGAERAIL
                     GAMRDAGLNAEDIGYINAHGTGTAANDKTECAAVAHAFGHHADKLMISSTKAMHGHVIG
                     GTGAIELLACVMALREGIIAPTIGYEEPDPECALNVVPNVAREEKVGAVLSNAFAFGGL
                     NAVIALKRA"
     aSDomain        complement(20292..21290)
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JGR78_RS08470_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.30E-56"
                     /label="JGR78_RS08470_PKS_KS.1"
                     /locus_tag="JGR78_RS08470"
                     /protein_end="407"
                     /protein_start="74"
                     /score="183.4"
                     /tool="antismash"
                     /translation="YDRFTQFTLLAAKEAVAQSRLNFQGELGLCSGVVLGTAGGGLNTW
                     DKNYRAVYEEGKNRVHPFVVPKLMNNAAASHVSMEFSLRGPAFTVATACASSNHAMGLA
                     FQMVRSGAARVMLSGGSEAMLCFGGIKAWEGLRVMSRDACRPFSANRNGMVQGEGAGVF
                     VFEDWDHAAARGADILAEVVGFAMSADAQDIVMPSAQGAERAILGAMRDAGLNAEDIGY
                     INAHGTGTAANDKTECAAVAHAFGHHADKLMISSTKAMHGHVIGGTGAIELLACVMALR
                     EGIIAPTIGYEEPDPECALNVVPNVAREEKVGAVLSNAFAFGGLNAVIALKR"
     CDS_motif       complement(20580..20627)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JGR78_RS08470_0002"
                     /evalue="5.80E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="JGR78_RS08470"
                     /protein_end="311"
                     /protein_start="295"
                     /score="9.5"
                     /tool="antismash"
                     /translation="YINAHGTGTAANDKTE"
     CDS_motif       complement(20991..21038)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JGR78_RS08470_0001"
                     /evalue="2.10E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="JGR78_RS08470"
                     /protein_end="174"
                     /protein_start="158"
                     /score="13.8"
                     /tool="antismash"
                     /translation="GPAFTVATACASSNHA"
     gene            complement(21524..21787)
                     /locus_tag="JGR78_RS08475"
                     /old_locus_tag="JGR78_08475"
     CDS             complement(21524..21787)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (6-57). E-value: 1.8e-12.
                     Score: 39.4. Matches aSDomain:
                     nrpspksdomains_JGR78_RS08475_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009815248.1"
                     /locus_tag="JGR78_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08475"
                     /product="acyl carrier protein"
                     /protein_id="WP_182791846.1"
                     /sec_met_domain="PP-binding (E-value: 1.2e-11, bitscore:
                     42.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQSIHDRIVAIIAEQTMLDPEQITLQATPVDLGIDSLGLVESIF
                     AIEEAFDIVIPFNANEPDQSDFDVSSLGSIIAAVERLVAEKE"
     aSDomain        complement(21617..21769)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JGR78_RS08475_PP-binding.1"
                     /evalue="1.80E-12"
                     /label="JGR78_RS08475_PP-binding.1"
                     /locus_tag="JGR78_RS08475"
                     /protein_end="57"
                     /protein_start="6"
                     /score="39.4"
                     /tool="antismash"
                     /translation="DRIVAIIAEQTMLDPEQITLQATPVDLGIDSLGLVESIFAIEEAF
                     DIVIPF"
ORIGIN
        1 gacacgatgg acgagggcgg gcggcaccgg gcgctggacc gcttcctcga cccctcgcgg
       61 gccgacggga tcatcctgct ggacgggcag gtgacgcagg ccgaccttgc cgcgctgccg
      121 caggcgccgc cgctggtcat ggcctgcgaa tggatcgagg gcagcgcggt gccctgcgtc
      181 gtgctggaca acgcgctggg gacggaactc gccgcccggc acctgcgtga gcttgggcac
      241 cagcggatcg gctggatcgg cggcccgccc ggcaatgtgc tgcacaaggc gcggctggag
      301 gggctggccc gcgtgctggg gaaggtgccg ccgggctatc ccggcgactt ctctctgcaa
      361 tcggggactc gggcggcgca gatctggctt gcaggggcct ctgccctgcg ccccaccgcc
      421 atcgtcgcct tcagcgacga attggcggcg ggcttcatgg gcgaggtgca gcgccacggg
      481 gtcgtggtgc cgcgcgacgt gtcggtgatc ggcttcgatg ggatcgagtg ggtggctcac
      541 ctgccgaccc ccctgaccac catccgccag cccaagcgcg acctcggccg caccgccgcc
      601 cgcaccctga tccgccggat caacggggag cccatcgccg cccgcgaggt gctgaggccg
      661 gaactggtcc tgcgcgcctc gaccgcgccg ccggcctagg gcgtcagccg cagcagccgc
      721 ccgccgcgtc cgtcctcgat cagccagacc gcgccctccg gggacaccgc cacgtcgcgg
      781 atgcgggcgc ccatgttcca gcgttccgcc tcggccgcgc gtccgtcacg gcccacgacc
      841 gcccgcacaa gcgcctgccc ggacagcgcg ccgatcagcg ccgagccgtt ccagcccggg
      901 aacatcgcgc cctgatggaa gaccaacccg gccggcgaga tcacgggcgc ccacgacagg
      961 gacggccccg cgaagtcggg ccgcgtcgca tggtccggga tcggccgccc gtcataatgg
     1021 ttgccgttcg acacaaccgg ccagccgtag ttcgcaccgg gacggatcag gttcaactcg
     1081 tcgccgcccc gaggtcccat ctcgtgcgac cacagcctcc cgtccggcgc gaaggccagc
     1141 ccatagggat tgcggtgccc cgtggtccat gtctgccccc ggatgccgcc ctgtcgcgcc
     1201 caaggattgt cacggggcgt cgagccgtcg aggttcagcc gcaggatctt gccacggccc
     1261 tgatccgggt cctgcgcgct ggcgggctgc atccggtcgc ccacggtcag gaacaggtgc
     1321 cgcccccgcg ggtcgaaggc gatgatgccg ccgggctggc cgccgcctcc tcccggcgcc
     1381 tgccgccaca ccgcgccgag atcggccagc gccgcgcggt ttcccgagac cgtcagccgc
     1441 gcacgtgcca gcaccagccg gccgccctgc gcgggctcga cataggtgaa gaagacgcgg
     1501 gccgagcggc tgaaatcggg gcttgccgcg atgtccagca acccgttctg gccggatgcg
     1561 agcacgcgcg ggacattcgc caccggaacc ttctcgccgc gctggctgac aaggaagacg
     1621 cggccgggct tttccgtcac cagcatccag ccgccgggca ggaagcctat ggcccaagga
     1681 cggtcgaaac gggcaaccgc ctgcacggtg aagggctgcc gcgcctgcgc catggcaggc
     1741 atggctccca tcgccgcggg cagggtcagg gcaaggaagc tgcgacggtc catatcgcct
     1801 ccggtcacgg ggtgccgtgt ggccagggaa gccacccgtg ccacaggcca gtgtgacacg
     1861 ggccggcacg ggtggcgagg ttttcgccct tcccgtatgt tcggcctccg atacgcgaga
     1921 gagcaacagc gcgggatgtt cgcggctggc ctgccgacac gttgcacgcg cctttacagg
     1981 aaagcacccc gcggtgcccc tcttgtggtc tggcgccaag ctggttgatc ctcgcggaca
     2041 tgataccgac cgaccaaccc tcgagcttcc ctccgaccgc tttgccggtg ttggcatgac
     2101 cactcccgac tggccgagaa tcgcgctgac cggcatcgac ggaattgccg tcaccttcgc
     2161 cgcgcggctg accgagcccg cgaaccgtgc agcgctggcc ctgcgcgccg ccgtcgaggc
     2221 ggcaggctgg cccgaggtgc aggaaacggc ggcctcgctc gtctcggcct acctgcgggt
     2281 cgatccgctt tgcgacatga ctccgctggt ggcacggctg cgggcgctgg tcgcctcacg
     2341 cgactggacc gccgcgccgc tgcccgagga ccgcaagctt atccgcatcc ccacctgcta
     2401 tgacagcctc catgccccgc agcttgacga agcggccgag cttgccgggc tgacccgccc
     2461 gcaggcgatc gaggcgctgg cgacctcgtc cctgcgggtg ctgaccatcg gcttcgcccc
     2521 gggccagccc tatatcggcg aactgccgcc cgaatgggac atcccccgcc tgcgcgaact
     2581 gaccccacgg gttccggtag gggcgctgac agtcgcgatc cggcaactgg tgctgttcgc
     2641 ggtcgaggcg cagaccggct ggcgccatgt cgggcagacc gccgcgcggc ctttcgatcc
     2701 tgccgccccg cagcccttcc tgctgcgccc gggcgatgcg ctggccttcc ctccggtgga
     2761 tgccgaccgg ctggaggccc tgatgcgcga tccgaccggc ggcatcacca tcgagaccgc
     2821 gccatgagcc tgctcgtcct gtcctcgaac cccggcgtca ccatccagga ccggggccgt
     2881 cccggctggc tggcgcaggg gctgtcgcgc gggggcgcgg ccgacccggt ggcgctggcc
     2941 gagggcgcgg cgctgctggg gcagccggat aatcttgcag tggtcgagct tgccggggca
     3001 cccgcccgct tccgcgtgac tgcgccggca aggttggcac tgacgggcgc tcccttccgc
     3061 gccattctga gggatggcga ggaacgcccg cttgactgga acgcgatcca tctgctgccc
     3121 gccggatcgg aactggcgct gtatcccatc gaaggcggct ttgcctatct tgcgcttggc
     3181 ggggggatcg agacgccgct gatcctcggc gcgcgttcgg cgcatctggc ggcggagatc
     3241 ggagggcctc tttcggtcgg cggggaactg ccgctcggcc ccgattcggg cgaagcggcc
     3301 gatctggcgc tggaccccct gccccgcttc ggcggcggcg agatccgggt ggtggaaagc
     3361 ctgcagaccg cgctttaccc gcccgccgag atcgcgcggt tccagcgcag caccttccgc
     3421 cgcgacgcac gcggcaaccg catgggcgtg cggctgaccc ccgagggcgg cggcttcgag
     3481 cttgcgggcg ggctttcggt cgtctccgag atcgtccagc cgggcgacat ccagatcacc
     3541 ggcgacggca cgcccttcgt cctgctgagc gagtgccaga cgaccggcgg ctatccccgc
     3601 atcgccaccg tcctgccctg cgacctgccg cgcgtggcgc aggccccgcc cggcgcggcg
     3661 ctgaccatcc gcttcgtcac gcggaacgaa gcccgcaagg caatggcgga tcacgcgcag
     3721 gcgctggcgt cgttgcgcgg gcgggtgcgg ccgaggttgc gagacccatg ggcggtgccc
     3781 gacctgctgg gctacaacct gatcggcggc gtcgtcagcg cccatgaagg agacggacca
     3841 tgacccttca cgtcgatctg aatgccgaca tgggcgaaag cttcggccct tggacgatgg
     3901 gcgatgacgc ggcgctgctg gaggtgatct cgtccgccaa tgtcgcctgc ggggtccatg
     3961 cgggcgactg ggacgtgatg gcgcggacga tggaactggc cgtcaggaac ggcgtcggca
     4021 tcggcgcgca tccgggcttt cccgacctgc agggcttcgg ccggcgcgag atgcagatgc
     4081 ctttgcccag tgccgcaaac ctgatccgct ggcagcttgg cgcggcgcag gcaatggcgc
     4141 gggcggcggg cggagaagtc cgtcacctca agctgcatgg ggcgctggcg aacatggctt
     4201 cgcgcgacga ggcgcttgcc acggcctgtt tcgagggcgc gctgtcggtg gaccccggca
     4261 tcattttgat ggtgctggcg ggcaccgcgc agcaggcggc ggcgcagcgg ctgggcgctc
     4321 gggtcgcgtg cgagatcttc gccgaccggg cctatagcgc cgatgcgacc ctgctggaca
     4381 ggcggctgcc gggggcggtg atccatgatg ccgccgaggc ggccgcgcgg gtggtgcgga
     4441 tggtcaaggc gggcgcgatc ctgccggaag cgggcgtgtc gatcccgacc cgcatcgaca
     4501 cgatctgcct gcatggcgac acgcccggcg cgatccacat cgcgcgcagg gttcgcgggg
     4561 cgctggagga agcaggcatc agggtcgcga ggttcgaggg aactccactg cggtaaggct
     4621 gtttttgcgg ctcggccgga ccgggggctg tctgccccca tcgtcgcaca ggacgatccc
     4681 cgaggatatc tgcacgaaga agatggggct aagaggacag gcgttcagct tttcctgatc
     4741 cgtcgggcgc ggatcagggt gtgctggctg acgatttcga agcccaggcg ctccagcatc
     4801 tcgcggcgca ggcgggcgat ctcgtcgctg gcgatctcga tgacctcgcc ggtgtcgatg
     4861 tccaccacat ggtcgtgttc ggcggcgggc gtgatctcgt agcgcgatgg ctcgctttcc
     4921 agcgtcagct tgcggatcag cccagcctcc tcgagcgccg acagggtgcg atagacggtg
     4981 gcgagcgaga ccgaatcgtc cactgcccgc gcccgcgcca gcaactcgtc ggcattgggg
     5041 tggtcggcgg aatccatcag gatcgccaac agcaccatcc gctgctgcgt cacgcgaagc
     5101 cccgcatcgc gcagcgcctg ggcgaagtct gtcgtatgcg cgctcatccc gcctttcctg
     5161 cagatgggcc gaggttagcc ccatccggcg atgccggcaa caaatgagaa tcgctctcat
     5221 ctgcttgaca gatgcgaatg cgttgcattt acatggaggg agaaagcgga aaggaagtgg
     5281 catggcttcg cgcaaggcac gtcttctggc tgcaacgatg gcgctggcgc tgaccgcagg
     5341 ggcggcgcag gcgcaggagc ggatgaaggt cgcgaccacc ttcaccgtca tcgccgacat
     5401 ggcccgcaac gtcgcgggcg atgcagccga agtggtgtcc atcaccaagc ccggcgccga
     5461 ggtccatgga tacgagccga cgccgcagga catcgtgggg gcacaggacg ccgacctgat
     5521 cctgtggaac gggctgaacc tcgaacgctg gttcgagcag ttcctgggaa acctcaggga
     5581 cgtgccctcg gccacggtca gcgatgggat cgcgccgatg cccatctcga gcggcgacta
     5641 cgagggcagg cccaaccccc atgcctggat gagccccgcc aacgcgctga tctacgtgga
     5701 caacatcgcc gccgccatgg ccggggtcga tccggcgaat gcaacgacct atgcggccaa
     5761 tgccgaaggc tacaaggccg aactgaccgc cgcgctggaa cccctgaagg cgcagatcgc
     5821 ggagatcccg gaaccgcggc ggtggctggt gacttgcgag ggggcgttca gttacctcgc
     5881 gcgggacttc gggatgaagg aattgtatct ctggccgatc aacgccgacc agatgggcac
     5941 gccccgtcag gtccggcagg tgatcgacgg cgtgcgcgag aacgacatcc cggccgtctt
     6001 ctgcgaaagc accgtcagcc aggcgccggc cgagcaggtc gcccgcgaga ccggcgcccg
     6061 gtacggcggc gtgctttacg tggacagcct gtcggaaccg gatgggccgg tgccgagcta
     6121 tctggacctg atgcgcgtca ccgcgcagac catcgcggac gggctgaccg ccgggatcgc
     6181 ggaacaggac tgacagatgc cccccatgtc gcctgcgaaa gaccccggca tcgtcgcgcg
     6241 tgacgtgacg gtgacctatc gcaacggcca cacggcgctg cgccatgcgt ccttcgagat
     6301 cccgcagggg acggtcacgg cgctggtcgg cgtgaacggc gccggcaaat ccacgctgtt
     6361 caaggcgatc atgggttttg tccccgtcgc gtcgggcgag atccggctgc tggggctgac
     6421 cgtgcgcgag gcgctgcggc gcaacctcgt ggcctatgtc ccgcaggccg aggaggtgga
     6481 ctggaccttc ccggtgctgg tcgaggacgt ggtgatgatg ggccgctatg gtcacatggg
     6541 cttcctgcga cgcccctctg ccaaggaccg cgcggcggtg gatgaggcgc tggcccgcgt
     6601 cggcatggcg gacctgcgcc atcgccagat cggagaattg tcgggcgggc agcggaagcg
     6661 cgtcttcctt gcccgcgcac tggcgcagga cgggcgggtg atcctgctgg acgaaccctt
     6721 caccggcgtg gacgtgggca ccgaggaccg gattatccag cttctgggcg agttgcggga
     6781 cgaggggcgc gtgatgctgg tctcgaccca caatctcggc tcggtgcccg agttctgcga
     6841 ccgcgtggtg ctggtcaagg gcaccgtgct ggcgcatggc ccgaccgaga cgaccttcac
     6901 gcgggaaaac ctcgaacgcg ccttcggcgg cgtgctgcgg catttcacgc tgggcggcga
     6961 ggcgctgcat gacgacgacg atccgcgcca cgtcaccatc ctgacggacg acgaacgccc
     7021 gctggtgcgc tatgacaacc gcacccagat acgcgaaagg gccgaggacg catgatcctg
     7081 ctggagccct ttgcctacgg ctacatgacc aacgccatgt gggtttcggc gctggtcggc
     7141 ggagtctgcg ccttcctgtc ggcctacctg atgctgaaag gctggtcgct gatcggggat
     7201 gcgctgtccc attccgtcgt gccgggagtc gccggggcct acatgctggg gctgcccttt
     7261 gcacttgggg cgttcatctc gggcgggctg gcggctgcgg cgatgctgtt cctgtcggac
     7321 cgctcggggc tgaagcccga cgtggtgatc gggctgatct tcaccggctt cttcgggctg
     7381 gggctgttca tggtctcgct gaaccctgtc gcgatctcgg tccagacgat caccatgggc
     7441 aatatcctcg cgatcacgcc cggcgatacg gtgcagcttg ccatcatcgg cttcgtctcg
     7501 ctggcggtgc tgctggcgaa gtggaaggac ctgatggtgg tcttcttcga cgaggcccat
     7561 gcccggtcca tcggcctgcg tcccggtctg ctgaagggcg tgttcttcgt gctgctgtcg
     7621 gcctgcgtgg tggcggcgat gcagacggtc ggcgccttcc tcgtcatcgc catggtggtg
     7681 acgcccggcg cgaccgccta tctgctgacc gaccgctttc cgcgcctgat cgcgctgtcg
     7741 gtcgccatcg gcacggccac gagcttcctg ggcgcctatc tcagctattt ccttgacggc
     7801 gcgaccgggg gaatcatcgt ctgcctgcag acgctggtgt tccttgccgc cttcgtctgg
     7861 gcgcccaagc acgggctgct ggccgcccgc gcccgcgcaa ggggcgcatc gtgatcgaga
     7921 cgctgcttgc cccctttcag ttcggcttca tgcagaacgc cttcctgatc gcgctgatcg
     7981 tctcggtccc gacggcgctg ctgtcctgct ttctggtgct gaagggctgg gcgctgatgg
     8041 gggatgccgt cagccatgcg gtgctgccgg ggatcgtgct ggcctatgtc cttggcctgc
     8101 cgctgatctt gggcgccttc gcggcgggaa tgctcacctc ggtggcgacc ggctacttgg
     8161 ccgagaacag ccgggtgaag caggacacgg tgatgggcgt cgtcttttcc ggcatgttcg
     8221 gactggggat cgtgctttac acggcgatca cctcggacgt gcatctggat catatcctgt
     8281 tcggcaacat gctgggggtg cagccgggcg acctgtggac ggcggggctg atatcggtct
     8341 tcgtcacggc ggcgctggcg ctgaagtgga aggacctgat gctgcacgcc ttcgacccgg
     8401 cgcaggcgag ggcctcgggg ctgagggtcg ggctgctgca ctacgggctg ctcacgatcc
     8461 tgtcgctgac catcgtggcg acgctgacgg cgactggcct gatcctcgcc gtcggtctgc
     8521 tgatcgcgcc gggggccatc gccttcctgc tggcccgcag cttcgggcgg atgctggtcg
     8581 tggcggtggc ggtctgcatg agcgggatgc tggcgggggt ctacgccagc ttcttcctcg
     8641 acagcgcccc cgccccgacg atcatcctgg tcctgacggc gggtttcatc gcggccttcc
     8701 tgcgccggca atggcagatg cggcgggcgc agaacgctgg ctgagcggct tgtgccgctg
     8761 tcgccacagg tcgatggtgc ctgccgacaa tcacggacaa gcggatcatg gcgacgacat
     8821 cacccccgcg tcggccgggc ggcatcccgc gagggctggc cgataccggg ccggtgctgt
     8881 tctcctacgg gttccggccg ttcttcctgg gagccgggct gtgggccgtt gcggcgatgg
     8941 cgctgtggat cgcggccttg gccggggttg cggaaccggg cggaacctac ggggccgcga
     9001 actggcacat gcacgagatg ctcttcggct tcgcctcggc ggtgctggcg ggatacctga
     9061 tgacggcagt gccgaactgg acagggcgga tgccggtttc gggtccgccg ctgatggcgc
     9121 tcgcggcgct gtggctggcg ggaaggctga tgctgacctt tccgctggat gcgccgtggc
     9181 tcgcggttgc ggtcgaggcg ctgttcctgc cggtcatggc ggccgtcttc ctgagagaga
     9241 tcatcgcagg tcgcaaatgg cgtgacctca agatcgtcgg gctggtggcg ctgatcgccc
     9301 ttgccaacat cggctttcac gcggcggtgc ttggcggcgg cgatccgaga cttgccgcaa
     9361 gggcagcggt ggcgggcttc atcgccctga tcctgatcgt cggcgggcgg atcacgccga
     9421 gcttcacccg caactggctt gcccggatga agcgggcggc acggcccgcg cccgccgacc
     9481 gcttcgatac ggtgacggtt gcggtttcgc tggcggcatt ggtcctgtgg gttggctggc
     9541 ctgaaaacca ggtcctcatg ctggcagccc ttgctggcgc cgcgctgaac cttatgcggc
     9601 ttctccgctg gaggggctgg cacgtcaccg agccgatggt tctggcgctg cacggcggct
     9661 acctgatggt cgccctaggc tttgccgcca tcagcgcagc cgcagcgggc tggatgagcc
     9721 atgccgcagc cctgcatgtc ttcgccatcg gcgccatcgg gggcgagatg ctggctgtga
     9781 tgacccgcgc cagccgcagc cacaccggcg cggagaccga cgccgacctg actgccaccc
     9841 tcagcttcat cgccatcatg ctggcggccg tggcgcgggc ggcggcggat tttgcagcct
     9901 acgatgccct tgtcatactg tcgggcctgt catggatcgc ggctttcggg ctgttcaccc
     9961 tcggccatgc ccgcctgctg gcggccaccc gccgcagccg ctaacgcggc atccgccggt
    10021 attcgaaggc aggcgccggg gcgctcgtct cggcctcgat cagcgcgtcg agtgccgcgc
    10081 gatggggcga gcggcggcac acagggtccg tcgcccgcgc gtcgccggca atcgccatcg
    10141 cctgacagcg gcagccgccg aagtcgatgt cgcggcgctc gcaggtctgg cagaggtccg
    10201 gcatccagtc ggtgccgcgg aaggcgttga aggcggggcc gtcgttccag atctcggcca
    10261 gcggagtcgt caggacgttc tggaaggtca gccccagaat gatctcggcc gcgtggcagg
    10321 gcagcacctt gccctcgggc gtgacgttca gcccggtcga gccccagccg ttcatgcagg
    10381 cctttgggaa atccgcgaag taatccggtg gcacgaagtc gatggcgagc ctgcccgcat
    10441 aatccaccct cgcctgcgcg accacgcgct tggcctcgtc cacctgttcc cgcgtgggct
    10501 gcagggccga gcggttcttc agcgcccagc cctggaactg gacgcaggcg atctcgatcc
    10561 gccgggcgcc aagatcatgc gccagcgcga tggtctgcgg caggtcgcca aggttatgac
    10621 gatgcatcac tgcgttgatc gtcagcggaa agccgatccg ggcgatttcc gccgcgacca
    10681 tcatcttgcg gtcaaagccg cccttgtagc cgccgaccgt gtcggcgatt ccggcgttca
    10741 ccccctgaac ggacaactgc acatggtcca gcccggcggc gtcgagttcg tccagtcgcc
    10801 tgcccgtcag cccgatcccc gaggtgatga ggttcgtgta aagccccgcc tcgcgcgccg
    10861 ccgcgacgat ctggacgagg tcgggacgcg aggccggttc cccgcccgag atatgaagtt
    10921 gcaggacgcc catgtcggcc gcctgccgga agaccccggc ccattgttcc gtcgtcagtt
    10981 cccgttcccg cgcggtcagt tccagcgggt tcgagcaata ggggcaggac agcgggcagc
    11041 gatgggtcag ttccgccagc atggccagcg gcggatcggg gcgcggccgg acctgccgga
    11101 cgggaacggg tgtgggatgc actacggtca tgtcgcctcc accagccggc gcgcggccat
    11161 gtcgtcgagg aactcgatca cgtcggcctc gatcatctcg accggcgcgg catagcgttc
    11221 cgcaagggct gcgctgattg tggcgatgtc gcgcgtcccg tcaacctcgg ccagcaccgc
    11281 ctgccccacc tgatcgagca tcagcgcggt ttcagggccc agcaggacgg gcatgtcgcg
    11341 cacgcggtca tggtgcaacc gcactccccg gggcaggaaa ggacggtcgg cgggtgtcat
    11401 ccggcgtcct ccagcagccc ctcaccgggc tgccagccgc ccggcgggat gcggccgggc
    11461 gcgacatagg ccgaatgcag cgcgtcgagt tgcgcccaca gcacatccgt cttgaaggtc
    11521 agggcggcgg cggccatctc ctgctgctct tcagtgcggg catggtccag cacccaagca
    11581 agcccgaagg ccacgtcctt gggcgcctcg gtcagccggt gctggaagta gctgatcgtc
    11641 tgcggattgg cgaaatcgta atgcgcgagc agcccactga tgcgctgttc gtggatcgcg
    11701 ggcgcgaaca attccgtcag agacgaggcc accgccgcca gcagcggctg ttcgcggaca
    11761 tagcggacat aggcatccac ggcaaagcgc gtcgcgggca gcacgccgcg ggtcgaagcc
    11821 acgtaatcgg ggtcaagccc cacgccttcg gccagccgca gccagcgcca gatgccgccc
    11881 ggctgttcgg cggtgccgtc gtgatcctcg atccgcgagc gccaggcgcg gcgcaggtca
    11941 tggtcctcga cgcggctcat gaaggctgcg tccttcatcg ggatgcgcga ctgatagtaa
    12001 tagcggttga tgacccaggc ccggacctga tcgatggtgc agccgcctga atgcagcagc
    12061 gtgtggaagg ggtgcttgtc gtgataccgc tcggccccga tgcggcgcag gcgggattca
    12121 aaggcggaac ggttgggcgt gacatcgttc atagcgtgat ctccatcccg tcatgggcga
    12181 gttcccagcc ggccttcccg atctcggccc gttcagccga tccgggctgc agcacggggt
    12241 tggtgttgtt gatatggacg aagatgcggc gggtgccggt caggcccgcc agccgggcga
    12301 tgctgccgcc ctcgcccgac atcggcagat ggcccatgcg ggcgccggtc ttggcgccgg
    12361 tgccggtgcg cgacatctcg tcattcgccc agacggtgcc gtcgaacagc agcaggtccg
    12421 cgccctgcag gcgcgccaga agctcgtccg tcacctgcgc gcagccgggg atgtagaaga
    12481 ggcgtcggcc tacggcctca agcatgaggc cgacggtctg ctcgcccatc agcgcggtgt
    12541 caggctcgcc ttcctcaaga tacagcgcca ccttgccggg cacggcgaag gcggtgacgg
    12601 tcaggccgca gaggggggca aagggctttt caagctcgat ggtcgagcgg tccacatggt
    12661 ccgggttcag cacccggaag atcggctggt cgagaatctg cagcgtctcg gaggtcgcat
    12721 ggacggtgaa gggcgtgctt tcccgcagat tcagcaggcc cgcgacgtga tccacgtcgc
    12781 cattggtcag caccactgcc ttcaccggac tgccgcgcaa atccggggga tgcaggccgc
    12841 aggcgtcaag ctgcgcccgg atgtccggcg aggcgttcag gaccacgctc tgcccacccg
    12901 aggacagtgc gaccgaggat tgcgtcatcg ccgcgatgcg tccggttcgc gcgtcgttgc
    12961 agttcgtgca gccacaattc cattggggca gcccccctcc ggcggctgcc ccaagtattc
    13021 tcagcttcat cccttggcgg gcgtcagaga acgtcgcggg cgtcgcggtc gtcctcggcc
    13081 ggaccgtaca tgttgatttc catcccgcac ttcacttcgc gcgccttggg ctttgaccag
    13141 atcatacgtc atctcctcgg taggtggcat atgagtcaaa acgtgggcgc gcgaagggcc
    13201 tgtgtcaacc ggggcgaaga atgatcagcc ttaggtcgca ggaacgtcag gctgcgtgag
    13261 cggcggggaa agaccctgga agccgctgcc gcataagggt tatgcatggg caggagccat
    13321 cgggaatgga aaaaccggaa cttgcggcac aggtccgaaa ggcatccatc ccgaccgcac
    13381 gcggatagcc ggcctctgcc atggaaaggg ccggctccga ggaaccggcc ctgtcagcca
    13441 tgaggaaagc tcaggcgccc ttgagggtct tggcgacctc ggcggcgaag tcttcctctt
    13501 tcttctcgat gccctcgccc acggcgacgc gggcgtaagc cgacacttcg acgcccgcgt
    13561 ccttggcggc ctgttcgacc gtgacctcgg ggttgatgac gaaggactgg cccagcaggg
    13621 tgttttccgc cacgaacttc ttcatccggc ctgggatgat gttgttctgg atcactgctt
    13681 cgggcttcgg cttggccgaa gcggcatttt cttccatcgc cttggcggtc tggacttcaa
    13741 gctcgcgcgc cagcagcgtc tggtccatgg tcgattcgga cagcgacagc ggattggtcg
    13801 cggcgatgtg catggcgatc tgcttgccga tctcctgcgc cttggcggca tcgcccttca
    13861 acgcgaccag aacgccgatc ttgcccatgt tcggggcagc ggcattgtgg acgtaagaga
    13921 cgacgttctc gcccgaaacc gtgaccatgc ggcgcagggt caggttctca ccgatacgcg
    13981 agatggcctc ggtcacgacc tcgccgacgg gcgtgccgtt cagttgtgcc gccgccagtg
    14041 cttcggtcga atccacggtc aggccggtct gcgcgatgtc gcggaccatc gactggaacg
    14101 cttcgttctt ggcgacgaag tcggtttccg agttcacctc gaccgccacg cccttgccgc
    14161 cttcgacggc gacggcgacc agcccttcgg cagcgatgcg gccggatttc ttggcggcct
    14221 ttgccaagcc cttggtgcgc aaccagtcaa ccgcggcttc catgtcgccc gaggtttcct
    14281 gaagcgcctt cttggcgtcc atcatacccg cgccggtcgt ctcgcgcagc tctttcacca
    14341 tcgcggccga gatagccatg tgggtgtctc ccttgatctt ggaacaggtc aggcggggca
    14401 tatccccgcc tgatgaaagt ctggtgatga cgggccgatc aggcgtcggc ggtctgctcg
    14461 gccgcgggct cttccgcctc gatgccgtcg aactcctcga ccggggcgtc ggtcagcgcg
    14521 ccgagatcga cgccggcagc gcccatctgc gcggtcatcc cgtccagcgc cgcgcgggca
    14581 accaggtcgc aatacagcgc gatggctcgg gccgcgtcgt cgttgccggg gatcacgtgt
    14641 tcgatgccct tgggcgagca gttggtgtcc acgatggcca caaccgggat gcccagcttg
    14701 ttggcttcct gaacggccag gtcttccttg ttcacgtcga tcacgaacag caggtccggc
    14761 aggccgccca tgtcgcggat gccgcccagg cttgcctgca gcttggcctg ctcacgctcc
    14821 atccccaagc gttccttctt ggtcagccct tcggcaccgg cggccatcgc ctcgtccagc
    14881 tgcttgaggc gctggatcga ctgggaaacc gtcttccagt tggtcagcgt gccgcccagc
    14941 cagcggtggt tcatgtagaa ctgcgccgat ttctcggccg catccgccac cgagcgctgc
    15001 gcctgccgct tggtgccgac gaacagcacc cggccgccct tggccacggt gtcgcggatc
    15061 acctgcagag cgcggtccag catcgggacg gtctgcgtca ggtcgaggat gtggatgccg
    15121 ttgcggtcgc cgtagatgta ttcggccatc cgcgggttcc agcgctgggt ctggtgaccg
    15181 tagtgaacgc cagcttccaa gagctgacgc atggagtatt cgggaagcgc catatcgttt
    15241 cctttccggt ttgcgcctgg gacgagggat caggggtttc ccccaaccgg tggaccttgg
    15301 cggatgtctc ccgcccaagg cccgccctcg cctgtgaagt gcgcgccaga taggcgcaaa
    15361 gcggcccgat tgcaagcctt gatggccctg cccttcatcg gggcttgcga ggcggcgggc
    15421 cttgcactaa acggacccga ctgcacccgt agctcagctg gatagagtgc tgccctccga
    15481 aggcagaggt cacaggttcg aatcctgtcg ggtgcgccac cattccctgt ttgccctgcc
    15541 ctgcggaacc cgcgcctgtc cggcgccgtt ggcgtttccg aaagcaggtc tctcgtaagc
    15601 aagggaatat cggacatgaa ctccatcatc tatctggtcg gcctggtcgt cgtcgtcctg
    15661 ttcatcctct cgttgctcgg gctgcgctga tggaccggga agagcagcgc atccgcgccg
    15721 ccggtgcgcc cgcggtcgcg tccgacaggt cttatgtcga ttggggcgcg atcctggcag
    15781 gcgccgttgt cgcggccgcc ctttcggttg tcttcgccgc attcggcgca ggagtaggtc
    15841 tgggctcgat ctcggcccgg gccggtgagg ggctgggctt cggctcggtc atcctgaccg
    15901 gactgttcgt tgtcgtgaca atggtgctgt cctacatggc cggcggctat atcgccgggc
    15961 ggatgcgccg ccgcgtggat ggtgcgtcgc ccgaggaatc ggcggcgcgc gacggcatcc
    16021 acgggctggc cgtctggggc atcggcacca tcttcggggc gatcatgctg gccagcgcca
    16081 tcggcagcgc gctgaacgcg gccggttccg ctgcggccac tgcggtcgag gcgaccggct
    16141 cggctgtcgg cggcattgcg cagggcgtcg gcgccgtcgc gggtggggcg gtgcaaggcg
    16201 cgggccaact ggtcggcggc gcggcgcagg cgctgggcgg cgctgcggcc ggcacagggg
    16261 caacggcggc tgccagcggt gacggcgaga tcctgccggg actgccgaac cccatcgact
    16321 atgtcaccga caacctgctg cgcagcgagg cggcggcgcc cgaccagttc tcgaacgagg
    16381 cgatccgcag cgaggtcggc aacatcatgg ccaatgttgt ccgcacgggc gaaatcacgg
    16441 atcaggatcg cgcctatctg gaaagcgcca tcgccgcgcg cacgacgctg agccagcccg
    16501 aggtcagcgc ccgaatcgat caggcggtgg ggtctgtcca gcagttacgg gccgatgccc
    16561 agcaggcggt cgatcaggcg caggccgaag cgcagcggct gcgcgacgag gcggcggcac
    16621 aggccgagca gttgcgccag caggccgtcg aggcggccga gaccgcacgt cgcgcgggcg
    16681 tgctgtcggc cttcgcgctg gcggcctcgg ccctgatcgc ggcggccgcg gccttcatcg
    16741 gcgcgcagaa gggcggcaag gcgcgggacg aaggccgcat ctggggcggg ctgacccacc
    16801 ggcccctgcg gccccgctga gaccggcaac agcaccggaa cgggccgcca ttgcgcggcc
    16861 cgtccatatt tttgcgggtg gcgcttgagg gctgcgtggg ttagtccgcg cccgaaatcg
    16921 catcaaggcc cccgacatgg acatccgcaa catcgccatc atcgcccacg tcgaccacgg
    16981 caagacgacg ctggtggacc agcttctgaa acagtcgggc agcttccgcg agaaccaggc
    17041 cgtcgccgaa cgggcgatgg attccaacga catcgaacgc gaacgcggca tcaccatcct
    17101 tgccaaggcg acctcggtcg aatggaaggg cacccgcatc aacatcgtgg acacccccgg
    17161 ccacgccgat ttcggcggcg aggtggaacg catcctgtcg atggtggacg gcgtctgcct
    17221 gctggtggac gcggccgagg ggccgatgcc ccagaccaag ttcgtgacct cgaaggcgct
    17281 ggcgctgggg ctgcgtccca ttgtcgtgct gaacaaggtg gacaagcccg cggccgagcc
    17341 cgaccagacc ctgaacgaag tcttcgacct gttcgccaac cttggggcgt ccgacgagca
    17401 actggacttc ccgcatgtct atgcctcggg cgtgaacggt tgggccgacg acagcatgga
    17461 cgggccgaag aaggacatgg gtgccctttt cgacctgatc ctgcgccatg tccctgcccc
    17521 ttcgcagctt gcccgcaagg acgagccgtt ccagatgctg gcggtgacgc tgggcgcgga
    17581 ccccttcctc gggcgcctgc tgaccggccg ggtcgaagcg ggcaccgccc gcgcgggcga
    17641 cacgctgaag gcgctgtcgc gcgacggcga acggatcgag cagttccgcg tgtccaagat
    17701 cctcgccttc cgcggcttga cccagaccgc cattagcgaa gccgtggccg gcgacatcgt
    17761 gaccctcgcc gggatgtcca aggccaccgt cgccgacacg ctggccgcgc ccgaggtgga
    17821 aacgccgctg caggccaagc ccatcgaccc gcccacgatc agcgtgacct ttggcatcaa
    17881 cgactcgccc cttgccggcc gggacggcaa caaggtccag tcccgcgtca ttcgcgagcg
    17941 gctgatgcgc gagggcgaga ccaacgtcgc catccgcgtc gaggacacgc cgggcggcga
    18001 ggccttcgtc gtctcgggcc ggggcgagtt gcagatgggc gtcctgatcg agaacatgcg
    18061 ccgcgaaggc ttcgagctgt cgatcagccg cccccgcgtg atcttccgcg acgaaaacgg
    18121 cgagcggctg gagccggtcg aggaagtcat catcgacgtg gacgacgact acaccggcgt
    18181 cgtgatcgag aagctgaccg gcgaccgcaa gggcgatctg gtggaaatgc gcccggcggg
    18241 ccacggcaag acccggatcg tggcccatgt gccctcccgc gggctgatcg gctatcaagg
    18301 cgagttcatg accgatacgc gcggcaacgg cgtgctgaac cgcatcttcc acgactgggc
    18361 gccttacaag ggtccgatcc aggggcggcg gcagggcgtg ctgatctcga tggaggacgg
    18421 cgtgtctgtg gcttacgcgc tgtggaacct cgaggaacgc ggccgcctgt tcatcggggc
    18481 gcaggaacaa gtctatcaag gcatgatcat cggcgaacat tcccgcgaca acgatctcga
    18541 ggtgaacccg ctgaagggca agaagctgac caacgtccgc gcctcgggca cggacgaggc
    18601 ggtgcggctg acaccccccg tgcggatgag cctcgaagaa gcgatcgcct atgtcgacga
    18661 cgacgaactg gtcgaggtca cacccaagat cgtgcggctg cgaaagcgcc acttggaccc
    18721 acatgaacgc aaacgtcagg cgcgtaccga aagctgattg tcatcggaac agttcacgtc
    18781 caagttgacg catactgatc tgtgtcactt gcggggaaag ctccggtgaa acccggcgaa
    18841 tcggccatgg acgtccttct gcgggctgcc tgcgagcggc tggtgacggc cgatccgccc
    18901 tgctgcgagc ctgacagcct ggcgtcggaa gccggcatcg accccgcggt ggcccgcagc
    18961 ctgcttccct cgaccgaagc cgtcctgcag aatatcgcgg aaagcgcgct gcgccggcag
    19021 cttgaccacc tgacccggcg gctgagcggc ctgtcggacc agacgcccgc gcatcaattg
    19081 gtggaactgg gccgcgccta catcgaatgg gcgatcgaga accgcaacga tttccaggtg
    19141 ctgaactcac ggatgatccg cggcacattg gacaaggaag aggtcaaccg ttaccacaac
    19201 gcgctgcagc acctgaccct ctcgatgctg acgcgcgccc gcgatcaggg ccagttgcgc
    19261 ccggacatgg acccgatgct gctgtcgctt gtgtcgcgcg cattcagcta tgggctcgcc
    19321 cggctttacg tggaccggca gcttgcgctg tgggaagtgg gcgaccccga cgaggatgaa
    19381 tacaccaagg ccacggccgc cctggaaggc ttcgccgacc tgctgctgac caactggcgg
    19441 agggatcagc ccgcagcttc caaggcatag cggccggggc ttgccgagaa cacgaacgct
    19501 tggctgccgt tcaggaagac gtggcggctc gtttcatctt cagactgctc ccggccggtg
    19561 aggttgcagc cgttctcggc aagaagcccg gcgatggcgg cggcaggttc aggcggcggt
    19621 cagaacgaag ccgcagccct cgcccggctc agatctgctt ctcgggcatc tgcacgacaa
    19681 gcccgtccag ttccggcgtg accttgatct ggcaggtcag gcgcgagcgg tctgggtcgg
    19741 gctgccaggc gaaatcgagc atgtcggcct ccatcggatc gcggggcggc aggcggtcca
    19801 cccattcggg ggcgacatag acgtggcagg tggaacaggc gcaggcaccg ccgcaatcgg
    19861 cctcgatgcc cggaatgccg ttgtcgcggg cgccttccat cacggtcatg ccgggacgca
    19921 cctcgacctc gtgccgggtg ccgttccatt cgatataggt gatcctggcc atcagcgggg
    19981 tcctttgtct gcagccatgg ggataagcga tgaccgcgcg gatgaaaaga cgcgagcttg
    20041 cgccctcgtc acggccgcat gggtatttga cccagaaaga agcctcttaa cctgatctca
    20101 ggatttctgc cgcatcttcc gaatcgcggt acaggctggg gagccgatga ccgcccagag
    20161 agaagtcgcc ccggccatcg tggtgagaca tcccgttccc gtcagaccgg cgggggtggc
    20221 cggggcgcaa ccccgtggct tctttctggg tcaaataccc atgcgaggtt tcgaccgggc
    20281 gcaggtcatg cccgtttgag cgcgatcact gcgttcagcc cgccgaaagc gaaggcattc
    20341 gacagaaccg cgcccacctt ctcctcgcgg gcgacatttg ggacgacatt cagcgcgcat
    20401 tcggggtccg gttcctcata gccgatggtg ggggcgatga tgccctcgcg caaggccatg
    20461 acgcaggcca gaagctcgat cgcgccggtg ccgccgatga catggccgtg catggccttg
    20521 gtggaagaga tcatcagctt gtcggcatgg tggccgaagg catgggccac cgcggcgcat
    20581 tcggtcttgt cattggccgc cgtgccggtg ccatgggcat tgatgtagcc gatatcttcg
    20641 gcgttcaggc ccgcgtcccg catcgcgccc aggatggcgc gttccgcccc ttgcgcggat
    20701 ggcatcacga tgtcctgcgc gtccgccgac atggcgaagc ccacgacctc ggccaggatg
    20761 tcggcgccgc gggcggccgc gtggtcccag tcctcgaaga cgaagacgcc cgcgccctcg
    20821 ccctgcacca tgccgttgcg gttggccgaa aacgggcggc aggcatcgcg ggacatcacg
    20881 cgcagcccct cccaggcctt gatgccgcca aagcacagca tcgcctcgga cccgcccgac
    20941 agcatcaccc gcgccgcgcc cgagcggacc atctggaagg caaggcccat cgcgtggttc
    21001 gagcttgcgc aggccgtcgc caccgtgaag gccgggccgc gcaggctgaa ttccatgctg
    21061 acatggctgg cggccgcgtt gttcatcagc ttcggcacca cgaagggatg gacgcggttc
    21121 tttccctcct catagacggc gcggtaattt ttgtcccaag tgttcagccc gccgcccgcg
    21181 gtgcccagaa ccacgccgga acagaggccg agttccccct ggaagttcag cctggactgg
    21241 gccaccgcct ctttcgcggc cagcagcgtg aactgggtga atctgtcgta aagcgagatc
    21301 tgctggcggt tgaaacaggc ctcggggttc cagccacgga cctgggcgcc gatgcggacg
    21361 gaaagccgct cgacatcctg gaagtccagt gcaccgatgc cgcagcggcc ttcgcgcatg
    21421 gcctccagcg tctcgggcac gttgcggccc agcgcattga tcgtgcccat gccggtgatt
    21481 gccacccggc gcggaccctg gggcgccgcc atggttggcg cactcattcc ttttcggcca
    21541 ccagcctctc gacggcggcg atgatcgagc ccagcgacga gacgtcgaag tccgactggt
    21601 cgggttcgtt ggcattgaag gggatgacga tgtcgaaggc ttcctcgatg gcgaagatcg
    21661 actcgaccag gccgaggctg tcgatgccga ggtccaccgg cgtcgcctga agggtgatct
    21721 gttcggggtc gagcatcgtc tgctcggcga tgatggcgac gatgcggtcg tgaatgcttt
    21781 gggtcatggg cgctttcttc aatccttctg catcagccgt gtgacggtct tctgcagttc
    21841 ggcgaattgc gcggccatcc gcggcaaccg gcgcatggcc ttgttgatct cgatctgggt
    21901 ttccatcttc accgccggcg atccgaggat cacccgcccg gccgggacat tggtgaagat
    21961 gttgctggcg ccgcccgcga tcacgtcgtc gccgacgaag atgttgtcgt tcaccgccgc
    22021 ctttcccgcc agcacgaccc ggtcgccgat ccgggcagaa ccggcgaccc ccgccattcc
    22081 gcaaagcagg cagtcgcggc cgatgcggac gttgtggccg atctgcacga ggctgtcgat
    22141 cttggtgccc ga
//
