LOCUS       NZ_CP067225            24462 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Paracoccus sp. MC1862 chromosome, complete genome.
ACCESSION   NZ_CP067225
VERSION     NZ_CP067225.1
KEYWORDS    RefSeq.
SOURCE      Paracoccus sp. MC1862
  ORGANISM  Paracoccus sp. MC1862
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Paracoccaceae; Paracoccus.
REFERENCE   1  (bases 1 to 3307010)
  AUTHORS   Mingchao,X.
  TITLE     Paracoccus sp.MC1862
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3307010)
  AUTHORS   Mingchao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2021) Chinese Center for Disease Control and
            Prevention, National Institute for Communicable Disease Control and
            Prevention, Changping, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. HGAP 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 282.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016617715.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:33:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,607
            CDSs (total)                      :: 3,551
            Genes (coding)                    :: 3,394
            CDSs (with protein)               :: 3,394
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 65 of 157
            Pseudo Genes (incomplete)         :: 116 of 157
            Pseudo Genes (internal stop)      :: 29 of 157
            Pseudo Genes (multiple problems)  :: 44 of 157
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:42:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1649297
            Orig. end                         :: 1673759
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP067225.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24462
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24462
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24462
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14462]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14462
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    31..44
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(337..352)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.0"
                     /tool="antismash"
     misc_feature    338..352
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.77"
                     /tool="antismash"
     gene            346..756
                     /locus_tag="JGR78_RS08210"
                     /old_locus_tag="JGR78_08210"
     CDS             346..756
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011910615.1"
                     /locus_tag="JGR78_RS08210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08210"
                     /product="acyl-CoA transferase"
                     /protein_id="WP_182791892.1"
                     /transl_table=11
                     /translation="MSTARETILAAIHTRLSALPAAALRGEVLPERVPADGLLILRDGE
                     PEVTLSPLRYHYQHRAEIEAVVQDPARDKAVDTLCASIGAALATDRTLGSLCDWAEAEA
                     PRPVDLPVDGAASLKAAVIPIVLHYTTAGPLA"
     misc_feature    493..495
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            780..1718
                     /locus_tag="JGR78_RS08215"
                     /old_locus_tag="JGR78_08215"
     CDS             780..1718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007427726.1"
                     /locus_tag="JGR78_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08215"
                     /product="phage tail tube protein"
                     /protein_id="WP_182804264.1"
                     /transl_table=11
                     /translation="MARAKGARELMALAFDTVYGTPPVSGFTGIPFASTTLGAEQPLLN
                     SELLGYGRDPLAPIKDAVTAHGDVVVPLDAEAFFWLKAAFGTPTATGMEAPYSHEFQSG
                     AWSLPGMSIETGMPEAPRHAVYSGCVLDQFSWQMQRSGLLTATARLVAQGETVARTSGA
                     GTPAELKLKRFGHFNGAITRNGSALGNVVSAEITYANNLDRIEAIRSDGRIDGADPSMA
                     ALTGRIEVRFADQTLVTQAMNGEACELEFAYSLLSGESFTFTVHAVYLPRPRIEISGPQ
                     RIQASFDWQAARDATLGRMCTAVLVNDIEDY"
     gene            complement(2123..2254)
                     /locus_tag="JGR78_RS18430"
     CDS             complement(2123..2254)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS18430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255434838.1"
                     /transl_table=11
                     /translation="MQIMQIMKVAIVAALLASAVVPATALADPAERSLNRLILSQTG"
     gene            complement(2398..2658)
                     /locus_tag="JGR78_RS08220"
                     /old_locus_tag="JGR78_08220"
     CDS             complement(2398..2658)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS08220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGR78_08220"
                     /product="hypothetical protein"
                     /protein_id="WP_182791890.1"
                     /transl_table=11
                     /translation="MIASFMMARDAFCREYETHSGGTATPMAASREDDGWSQRFAMSMT
                     GADSYVPASGGIKALDAFLAESGAGTPLGPEEEAALLTQRR"
     gene            complement(2615..3103)
                     /locus_tag="JGR78_RS08225"
                     /old_locus_tag="JGR78_08225"
     CDS             complement(2615..3103)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGR78_08225"
                     /product="hypothetical protein"
                     /protein_id="WP_182791889.1"
                     /transl_table=11
                     /translation="MQITVEILMAFADDELEADYSREVEAALARDPRLQAQLRVFIESR
                     RVLREAAAAPHPPANDTAPIARIRAAGTVPAATPFPQARSAPVPTNLDRRPLGETAAAL
                     ASAVIGLGLWQWGGPAPGLSEAQLAALDDLALGESRELPGGKRRDDRLVHDGARRVLP"
     misc_feature    3162..3177
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            complement(3163..3318)
                     /locus_tag="JGR78_RS18130"
     CDS             complement(3163..3318)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016432.5"
                     /locus_tag="JGR78_RS18130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_234450919.1"
                     /transl_table=11
                     /translation="MQELPVEQCEVLELVGIHELSSAEAAEVPGIPRGTVMSRLSRARL
                     PLAEKL"
     misc_feature    3536..3551
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            3738..4313
                     /locus_tag="JGR78_RS08235"
                     /old_locus_tag="JGR78_08235"
     CDS             3738..4313
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGR78_RS08235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGR78_08235"
                     /product="hypothetical protein"
                     /protein_id="WP_182791888.1"
                     /transl_table=11
                     /translation="MRMLLLMLLAATMALTVQPRVDAEGLWLVAPAFADDDDGPRRRSA
                     APARPIPLPQRAENEILARGLSDQGLAALQHGDFALLEQGVLGGGDSIARLRKPTRLTM
                     DEALAAVRQLVPAGRSDFNHFYRTEQAEACKGIDCPARRAAAAHRHGRYRAEPRARGAV
                     GGPHPPAPGRGREPALGPAARARQSPRC"
     gene            4313..>4657
                     /locus_tag="JGR78_RS18620"
                     /pseudo=""
     CDS             4313..>4657
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.5"
                     /locus_tag="JGR78_RS18620"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /pseudo=""
                     /sec_met_domain="Peptidase_S8 (E-value: 3.9e-07, bitscore:
                     27.2, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDPDSRTPGLVPQVELAAVDSFHRAGQDQRTDAFALIRAQDYLE
                     QQEARIVNLSLAGPANAALEAQVAGMAQAGMVLIAAAGNMGPSAPPIYPAAYPQVIAVT
                     AVDRDRGVCRR"
     gene            5022..5570
                     /locus_tag="JGR78_RS08245"
                     /old_locus_tag="JGR78_08245"
     CDS             5022..5570
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018633573.1"
                     /locus_tag="JGR78_RS08245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08245"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_182791886.1"
                     /transl_table=11
                     /translation="MSKRAVVVIDIQNDYFPDGKYELVGIEKAASNAARVIDAARKKGD
                     RVIHVRHIFPSDDAPFFTPDSEGSEINPAVSPQEGETVVVKNHPNPFLKTDLKKILDDG
                     GIEEVVVVGAMSHMCIDATTRAASDYGYRTTVVQDACATRDLEFGDVSVPAASVHAAMM
                     SALGFAYATITDTDSYVRQ"
     gene            complement(5758..6204)
                     /locus_tag="JGR78_RS08250"
                     /old_locus_tag="JGR78_08250"
     CDS             complement(5758..6204)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013066356.1"
                     /locus_tag="JGR78_RS08250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08250"
                     /product="YaiI/YqxD family protein"
                     /protein_id="WP_182791885.1"
                     /transl_table=11
                     /translation="MPIYVDADACPVKAEIERVATRHRLRVLIVSNGGIRPSANPLVET
                     VIVPEGPDEADKWIAERAGPGDVVITGDIPLASRCVAAGAEVLRHDGEALNSGNIGNAL
                     ATRDLMADLRAADPFRQGHGRGFTKADRSRFLDALERAARRAAR"
     misc_feature    6409..6427
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.38"
                     /tool="antismash"
     misc_feature    6412..6428
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    6546..6561
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.2"
                     /tool="antismash"
     gene            6872..8239
                     /locus_tag="JGR78_RS08255"
                     /old_locus_tag="JGR78_08255"
     CDS             6872..8239
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011748015.1"
                     /locus_tag="JGR78_RS08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08255"
                     /product="malonyl-CoA decarboxylase"
                     /protein_id="WP_182791884.1"
                     /transl_table=11
                     /translation="MIKTEPARPSRSAFLGELFEQLTERGRRLLGRRDGDRVVEALDLS
                     ELAELLLSRRGEASGVALARALLSAFEQADENARLAFLQTLAHRFGPDLDAVQAALAAV
                     QAEPASAEAVEALHIVAEPRRQELLRRLNLAPGGTAALVRMREELLRHLRDHPELRRVD
                     SDFAHLFASWFNRGFLVLRHIDWTTPANILAKIIRYEAVHEIRNWDDLRNRLEPTDRRC
                     YAFFHPQLADEPLIFVEVALTEAIPDNVASLLALDRQPIEAERATTAVFYSISNTQRGL
                     AGVSFGNLLIKQVVEDLKAELPDIRSFVTLSPVPGFAAWLAQQRDDAASDLLTPAQREA
                     FALLNRPGWHGDAQAVESLRAPLLAAAATYFLSARDAKGRMIDPVARFHLGNGARLERL
                     NFLGDLSPNGLRQSHGLMVNYLYDLDRIEANHEAFAERSTVAASGAVQRALPAPSS"
     gene            8261..9769
                     /locus_tag="JGR78_RS08260"
                     /old_locus_tag="JGR78_08260"
     CDS             8261..9769
                     /NRPS_PKS="Domain: AMP-binding (12-402). E-value: 1.9e-100.
                     Score: 328.3. Matches aSDomain:
                     nrpspksdomains_JGR78_RS08260_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007816920.1"
                     /locus_tag="JGR78_RS08260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08260"
                     /product="malonyl-CoA synthase"
                     /protein_id="WP_182791883.1"
                     /sec_met_domain="AMP-binding (E-value: 5e-106, bitscore:
                     352.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFETITQRVADPAATAIETPSGEHIAYADLIDRIGRMADALVD
                     LGVAPGDRVAVQVEKSVEAIILYLATVRAGAVFLPLNTGYTPAEVDYFLTDAEPRIFVC
                     DPVREEALRPLAETAGARVLTLDAAGRGSLADAAAGMAGDFATVPRADDDLAALLYTSG
                     TTGRSKGAMLSHGNLASNSLALVEAWRFSASDVLIHALPIFHTHGLFVATNVVLLSGAS
                     MIFLPKFDPDRIFAAMPRATVLMGVPTFYTRLLEDRRLDRETTQGMRLFISGSAPLLAD
                     THRAWQARIGHAILERYGMTETNMNSSNPYNGERIAGTVGQPLPGVEIIVTDPETGAEL
                     PGGEIGMIEVRGPNVFQGYWRMPEKTAAELRLNGFFITGDLGRFDERGYLHIVGRGKDL
                     IITGGYNVYPKEIETEIDALPGVTESAVIGLPHRDFGEGVTAVVVPAGLPALTEADVLH
                     PLESRLAKFKLPKRVVFVEELPRNTMGKVQKNLLRDRFADLYRP"
     aSDomain        8297..9466
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JGR78_RS08260_AMP-binding.1"
                     /evalue="1.90E-100"
                     /label="JGR78_RS08260_AMP-binding.1"
                     /locus_tag="JGR78_RS08260"
                     /protein_end="402"
                     /protein_start="12"
                     /score="328.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DPAATAIETPSGEHIAYADLIDRIGRMADALVDLGVAPGDRVAVQ
                     VEKSVEAIILYLATVRAGAVFLPLNTGYTPAEVDYFLTDAEPRIFVCDPVREEALRPLA
                     ETAGARVLTLDAAGRGSLADAAAGMAGDFATVPRADDDLAALLYTSGTTGRSKGAMLSH
                     GNLASNSLALVEAWRFSASDVLIHALPIFHTHGLFVATNVVLLSGASMIFLPKFDPDRI
                     FAAMPRATVLMGVPTFYTRLLEDRRLDRETTQGMRLFISGSAPLLADTHRAWQARIGHA
                     ILERYGMTETNMNSSNPYNGERIAGTVGQPLPGVEIIVTDPETGAELPGGEIGMIEVRG
                     PNVFQGYWRMPEKTAAELRLNGFFITGDLGRFDERGYLHIVGRGKDLIIT"
     CDS_motif       8726..8785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JGR78_RS08260_0001"
                     /evalue="4.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="JGR78_RS08260"
                     /protein_end="175"
                     /protein_start="155"
                     /score="22.4"
                     /tool="antismash"
                     /translation="AALLYTSGTTGRSKGAMLSH"
     CDS_motif       9284..9364
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JGR78_RS08260_0002"
                     /evalue="7.40E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="JGR78_RS08260"
                     /protein_end="368"
                     /protein_start="341"
                     /score="18.4"
                     /tool="antismash"
                     /translation="GGEIGMIEVRGPNVFQGYWRMPEKTAA"
     CDS_motif       9437..9499
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JGR78_RS08260_0003"
                     /evalue="2.70E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="JGR78_RS08260"
                     /protein_end="413"
                     /protein_start="392"
                     /score="13.7"
                     /tool="antismash"
                     /translation="VGRGKDLIITGGYNVYPKEIE"
     gene            10001..10906
                     /locus_tag="JGR78_RS08265"
                     /old_locus_tag="JGR78_08265"
     CDS             10001..10906
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="JGR78_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08265"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_182791882.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.8e-43, bitscore:
                     143.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEEFMRDAAKPIDWRSAVDLRLAEIARGFGRASPDLGRAMSDAV
                     LAPGKRFRAMVLLIAGEATGGVRPALIDAACAIELVHTASLVFDDLPCMDDAQARRGRP
                     TTHLVHGECRAILAGIALVTEAMRLLATARDADADTRARLVAVLAGAVGPQGLCAGQDL
                     DIHASKDVAGIQKEQDLKTGALFVAGFEMFGLLQRLGARDMETLSALGRTLGRAFQSYD
                     DLLDVQAEAGALGKDTGRDAHGHGPARGVLAVRSPAQAQAHYDALRAELDLLLGNCGFN
                     SLPLARHVGRVLPRRAIRAA"
     gene            complement(10910..11821)
                     /locus_tag="JGR78_RS08270"
                     /old_locus_tag="JGR78_08270"
     CDS             complement(10910..11821)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020503292.1"
                     /locus_tag="JGR78_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08270"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_182791881.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.6e-78,
                     bitscore: 260.4, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 2.6e-44, bitscore:
                     149.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPVAESQAAIAAGSQSFAAAAKLMPRGIREDTIMLYAWCRHAD
                     DVVDGQELGSAPQAGGDPEERLARLKAETLEALHGTGPMTPPFAALQAVARRHDFPDRW
                     PMDLIDGFAMDVEGRAYRTLNDTLDYSYHVAGVVGVMMARVMGVRDQAVLDRACDLGLA
                     FQLTNIARDVIDDARIGRVYLPGDWLDEAGATIEGDIPSPQLYAVILRLLDAAEPYYAS
                     AFAGLPALPARCAWSIAAAARIYRAIGARIRKGGPEAYRQRIGTSGAAKAGLALRALGD
                     AGRSRVLPPKPLREGLWTRPRA"
     gene            complement(11818..13311)
                     /locus_tag="JGR78_RS08275"
                     /old_locus_tag="JGR78_08275"
     CDS             complement(11818..13311)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020503291.1"
                     /locus_tag="JGR78_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08275"
                     /product="phytoene desaturase"
                     /protein_id="WP_182791880.1"
                     /sec_met_domain="DAO (E-value: 1.2e-07, bitscore: 29.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPRTAIVIGAGFGGLALAIRLQSAGIATTLLEARDKPGGRAYV
                     WREEGHVFDAGPTVITDPDSLRELWALSGQEMARDVTLLPVNPFYRLLWPDGKRFDYVN
                     DGNALEREIAAFNPADLDGYRRFHDYAEQVYQEGYLRLGTVPFLKLGQMLQAAPALVRL
                     EAYRSVHSVVARFIKDPHLRQAFSFHTLLVGGNPFSTSSIYALIHALERRGGVWFAQGG
                     TNALVSGMATLFQRLGGTLRLNAKVARIETEGARATGVTLADGTRLTADMVASNADVMH
                     SYRDLLGGTRRGRTKAALLKRQRWSMSLFVIHFGLSQRPEGLAHHTILFGPRYRELVNE
                     IFRGPKLAEDFSLYLHSPSVTDDSLAPPGMSTHYVLAPVPHLGRAAIDWAAEGEAYADR
                     ILASVEERLIPNLRANLRVKRIFSPADFASELNAHHGSAFSVEPILRQSAWFRPHNRDR
                     SIRNFYIVGAGTHPGAGIPGVVGSAKATAGVMLADAGAA"
     gene            complement(13308..14462)
                     /gene="crtY"
                     /locus_tag="JGR78_RS08280"
                     /old_locus_tag="JGR78_08280"
     CDS             complement(13308..14462)
                     /EC_number="5.5.1.19"
                     /GO_function="GO:0045436 - lycopene beta cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01789.1"
                     /locus_tag="JGR78_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08280"
                     /product="lycopene beta-cyclase CrtY"
                     /protein_id="WP_182804259.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 6.8e-113,
                     bitscore: 375.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPDLILAGAGLANALIALAVAEARPGARILMLDRAPSPSDAHTW
                     SFHDPDLRLPWHRRLSPAIRCRWPGQEVRFPDHSRVLRAGYASLDGAGLARLLADTPGV
                     TLRWNAGITALDATGATLGSERIEAPCVIDGRGARSSRHLVTGYQKFVGLEFEMNTPHG
                     VTRPLIMDATVPQQDGYRFVYLLPFSPTRLLIEDTRYSDGATLDEEAIVCAIADYASDK
                     GWTGREVRRERGVLPIALAHDAAALWAEAQGGPAPVGLRAGLFHPVTGYSLPVAAQVAD
                     VVAAAGPTTAEVFSAVCAHALDRAGDDRFLRLLNRMLFRGCPPDRRHRVLSRFYRLPEP
                     LIERFYAGKLTRLDRLRIVSGKPPIPIRDALPCLREAPLLKETA"
     gene            complement(14459..15667)
                     /locus_tag="JGR78_RS08285"
                     /old_locus_tag="JGR78_08285"
     CDS             complement(14459..15667)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012427.5"
                     /locus_tag="JGR78_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08285"
                     /product="glycosyltransferase"
                     /protein_id="WP_182804257.1"
                     /sec_met_domain="MGT (E-value: 9e-33, bitscore: 111.7,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARIAFCLPALSSHAAVHGALARRLAARGHDCRMVGGEGLGPLAA
                     REGLGFDSLGLCDPDLRGAGLVRTLLATAAATRSFVRRGPRALGRLSPDLVVADQAEPG
                     ASLAAEAAGIPRVTLASALPLDRDEAIPPPFVDWPFLAGKAGRKRNRGGWRVADALMML
                     QSRALAAGCRAHGLPLRRRIDEWISPDLDLRQLVPSLDFPHAPGRGARAVGPLRDDAAG
                     EFEIDTGGRPLVFASLGTLQGNRRGLLAAIAGAAEDLGVFLVLAHCGGLTEAEARALPG
                     APLVRDFFPQRAVLARADACVTHAGLNTVLDCAGAEVPMVAIPLAFEQPATAARLAFHG
                     AARVVPLRRATRAAIREALGAVLSDPSHRLALARPAAEIRAAGGATGAADLVEAQLQCR
                     LAA"
     gene            complement(15674..16201)
                     /locus_tag="JGR78_RS08290"
                     /old_locus_tag="JGR78_08290"
     CDS             complement(15674..16201)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016041.5"
                     /locus_tag="JGR78_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08290"
                     /product="sterol desaturase family protein"
                     /protein_id="WP_182804255.1"
                     /transl_table=11
                     /translation="MSVLGPILIVVLTVAVMEGVAYSVHRWIMHGPLGWGWHKSHHEET
                     HGPFEKNDLYAVIFAALSILLFVIGSRWWPWMWWVAVGMSVYGVIYFVVHDGLVHQRWP
                     FRYIPRRGYFRRLYQAHRLHHAVEGRDDCVSFGFVYAPPVDDLKARLKTSGVLARRQSR
                     HRDAWRPDRGED"
     gene            complement(16198..16920)
                     /locus_tag="JGR78_RS08295"
                     /old_locus_tag="JGR78_08295"
     CDS             complement(16198..16920)
                     /EC_number="1.14.19.-"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012699.5"
                     /locus_tag="JGR78_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08295"
                     /product="fatty acid desaturase"
                     /protein_id="WP_200559271.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 9e-06, bitscore:
                     22.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQALRRPLATSLIGMTLAAGVIGAWLALHIFAVWHLDATAHPLL
                     AGLCLIGLTWLSVGLFIVAHDAMHGAVAPGRPSLNAAVGGLALMLYAGFSWRKLIVKHM
                     AHHRHAGTDDDPDFGHGGPVRWYADFVRTYFGWREFWVLGGTVMLYALILGSRWPYVAF
                     WSVPSILASMQLFVFGTWLPHRPGHGDFPDRHNARSTIVSDPVSLLTCFHFGGYHHEHH
                     LHPAVPWWRLPSTRRDGA"
     gene            complement(17007..18026)
                     /gene="fni"
                     /locus_tag="JGR78_RS08300"
                     /old_locus_tag="JGR78_08300"
     CDS             complement(17007..18026)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: protein motif:HMM:TIGR02151.1"
                     /locus_tag="JGR78_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08300"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_182804253.1"
                     /transl_table=11
                     /translation="MNEIKGRKSEHLAIVGAGKGIQLSRATGFDNVHFLHNALPELDYD
                     AIDTATRFLGRRLSAPLMVSAMTGGTPGAARINLSIAEACGALGLALAVGSQRIAIEGR
                     GAGGLGPELRARAPDVPILGNLGAVQLRRGMGADEARRAVEMLEADALMLHLNPLQEAI
                     QPGGDRDFSDLLPRIEALARALPVPLGVKEVGAGLSADVGRRLMDAGVTILDVAGVGGT
                     SWARVEAERGGDRLRRIAAPFFDWGIPTAEAVSAMAPIMWPGTVLIASGGIRHGLDVAR
                     AIRLGADLAGQAAGALPAAREGAEALAAYLSEVIEQLRIAMFCTGSRDLEALRHAPLA"
     misc_feature    17996..18015
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.44"
                     /tool="antismash"
     misc_feature    complement(18013..18026)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.96"
                     /tool="antismash"
     gene            complement(18043..18663)
                     /locus_tag="JGR78_RS08305"
                     /old_locus_tag="JGR78_08305"
     CDS             complement(18043..18663)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025605.5"
                     /locus_tag="JGR78_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08305"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_182791875.1"
                     /transl_table=11
                     /translation="MRSKGVRNARFDERRGELLARLRGRLLLRGAGRPTLRELATAAGC
                     SVSTLNHYFGKRDDIVVAVFADSGRRGQGQFTATRQAGPQLDASVRDAAAMAWRALTQH
                     GVADALAMGMVEGMRNDLLGPAFIHSMFEPFVLALTERLDAHVARGQMRAVDTRMAALA
                     LASPLLLGALHQGQLGGARDYPLDGEAFLNHVVEGFLRAYRAG"
     gene            complement(18710..19300)
                     /locus_tag="JGR78_RS08310"
                     /old_locus_tag="JGR78_08310"
     CDS             complement(18710..19300)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022215.5"
                     /locus_tag="JGR78_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08310"
                     /product="DUF2585 family protein"
                     /protein_id="WP_182791874.1"
                     /transl_table=11
                     /translation="MNRPADMIPPRPVGGSLAFRGGQPLLTLALGILLINAAVVLWLLF
                     LGREFLPENVPLYWWNPSTALSHNSQHLTDFYSALHAISGAALFFLARRLRPGWPVGTR
                     LLLVIACSGLWEIVENTPWVISLFNDPDGIDVYQGDSIVNALSDTGFVALGFLAAHNFP
                     RWLVIAGGGLAEIAVALMIHDGFVLGTARMILR"
     gene            complement(19360..21882)
                     /locus_tag="JGR78_RS08315"
                     /old_locus_tag="JGR78_08315"
     CDS             complement(19360..21882)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008225451.1"
                     /locus_tag="JGR78_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08315"
                     /product="ABC transporter permease"
                     /protein_id="WP_182804248.1"
                     /transl_table=11
                     /translation="MTLRLAWTLARREMRGGLAGFRIFLTCLALAVAALAAVGTVRASI
                     EAGLARNGAALLGGDAEVELTYRFATGAERAALDRIASAVSETAEFRSMATVLRHGQSE
                     RALTQVKAVDDAYPLVGAVRLSPPISWDQALSSGGDPGAVMERVLAERLGLSPGDGFRL
                     GEQAFTLTAILDSFPDNAGESLALGPITIVRTSDLAQSGLLGPGTLFEAQYRLLLPPGT
                     DLGTARGQAMAALEGAGARWRDARDGAPGLSGFVDRLGAFLILIGLSGLAVGGVGVSAA
                     VRAWLDAKLPVIATLKSLGASRRVIFLTYLIQIGLMTALGIMLGLALGAALPLLLAPVI
                     EARLPMPATFGVFPGPLAEAALYGALAALAFALWPLALAADTRAAVLFRSAVDAGRRVP
                     RPRYLAMITALAGLFLLAAAAFSGNWRLTLWTLGGVAGTLALLAVVALLAAPLAGGLMP
                     LARRRPALRLALGALRTHRGDATGVVLSLGLGLAVLAVVGQIDGTLRRAIESEMPGVAP
                     SFFFVDVQPDQIGDFLTLARGNPGVSRVEAAPMLRGVVTRINGRPATEVAGDHWVVRGD
                     RGLTYSDNPPSRTTITAGEWWPAGYDGPPLISFSAEEAAEIGLSLGDTLTVNVLGRDIT
                     GTIASFRQVDFRNAGIGFVMSMNPAALQGAPHTWIATVYAGPEAETAILREIGDRWPNV
                     TAIPVGEAIERVAGLLAGIGAAVRWGAAATLVTGFAVLIGTALAAARARRYEAAILKTL
                     GASRGLILRSFALRAALLGLIAGIAAIAAGAVGGWAVAHFVLDTDHRVIWSSAVILVAG
                     GVIATLAAELAFALRALTVKPAAILRSE"
     gene            complement(21879..22556)
                     /locus_tag="JGR78_RS08320"
                     /old_locus_tag="JGR78_08320"
     CDS             complement(21879..22556)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008281941.1"
                     /locus_tag="JGR78_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08320"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_182791872.1"
                     /transl_table=11
                     /translation="MPDPVLSLDDVRLTLRSSAGPVEILHGITLAVEKGETVGLVGPSG
                     SGKSSLLMLMGGLEQATGGRVRALGHDLTAMGEDALARFRRDHMGIVFQSFHLIPTMTA
                     LENVAVPLELAHAPDAAARAREGLAAVGLAGRAHHYPSQLSGGEQQRVALARALAPRPA
                     ILLADEPTGNLDETTGAQIADLLFGMVRDSGTTLVMVTHAPEIAARCARIIRLRDGRLE
                     QAA"
     gene            22672..23319
                     /locus_tag="JGR78_RS08325"
                     /old_locus_tag="JGR78_08325"
     CDS             22672..23319
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005851366.1"
                     /locus_tag="JGR78_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08325"
                     /product="arylesterase"
                     /protein_id="WP_182791871.1"
                     /transl_table=11
                     /translation="MLARMIGITLLSALPAAAEPVTVAALGDSLTQGYGLPQQEGLVPQ
                     LQAWLRERGAEVTLVNAGVSGDTTAGGLSRVDWTLTPEVGGMIVALGGNDLLRGIDPAV
                     SRKNLSGILDAARKAEVPAMLIGIGAPANYGAEFQTAFNGVYTDLAQSYEVPLIPSMLD
                     AIVAARDPLSLMQPDGIHPNAEGVRVIVEGIGPQVLQFVAALGACEQGCTDG"
     gene            complement(23324..24286)
                     /locus_tag="JGR78_RS08330"
                     /old_locus_tag="JGR78_08330"
     CDS             complement(23324..24286)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011841962.1"
                     /locus_tag="JGR78_RS08330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGR78_08330"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_182791870.1"
                     /transl_table=11
                     /translation="MIRRNLLKLPLAAAALSLAAGAAFAQEAEKRVIGVSIPSATHGFM
                     GGLNWHAQDTIKRLGEVYPNLEFVLATAGDAAKQVSDIEDMLATRNIDGLVVLPFESEP
                     LTDPVRQVKAAGKFVTVVDRGLSEEGIEDLYVAGDNTAFGRVAGEYFRDNLPAGAKIVV
                     LRGIPTTLDNERVEAFQAALEGSDKEILDMQHGNWNRDDAFNVMQDYLAKYSEINAVWA
                     ADDDMAVGVLEAIAQAGRGDQMVVVGGAGMKDIVKRIMDKDPQLPVNVTYPPALISSAI
                     EMTALHFVSNAPMAGRYIIGSQLITPENAEAFYFPDSPF"
     misc_feature    24260..24274
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.78"
                     /tool="antismash"
ORIGIN
        1 accgacatcc tcgtgaccgc cggcctcggc tggaccgagg cgaagctggt cgcgggcttt
       61 gtcagcgcca cgctggtgct ggcgctgctg cccgccgccg cgattacgcg gcggctgaag
      121 ctatccgacc tgcgcgcctg acgcttacgc ccccgtcgcc gtgtcgctct gtgtcaagct
      181 gatgtgcgtg ccgacacgtc agcgagaaga tccgttgcac tgcagcgtcg aaatccagcc
      241 gtttcctcgt tgcgcctgca cttcctgcct cgacgccggg tgaagtcctg ggctcgaagc
      301 cggtgaagca ggagttcgcc gcaacagcat cgtgacctga aaaacatgtc cactgcccgc
      361 gaaaccatcc tcgccgcgat tcatacgcgg ctctcggcgc tgccggccgc cgcgctgcgc
      421 ggggaagtgc tgcccgagcg cgttccggcc gatggcctgc tgatcctgcg cgacggtgag
      481 cccgaggtca cgttatcgcc gctacgctac cactaccagc accgggccga gatcgaagcg
      541 gtcgtgcagg acccggcgcg ggacaaagcc gtcgacacgc tctgcgccag catcggcgcg
      601 gcgctcgcca ccgaccggac gctgggcagt ctctgcgact gggccgaggc ggaagcgccg
      661 cggccggtcg atctgccggt cgacggcgcg gcgagcctga aggcggccgt gatcccgatc
      721 gtcctgcatt acaccacagc tggcccgctg gcctgacccg acaatccgag gagacctcca
      781 tggcacgagc caagggggcg cgggagctga tggcgcttgc cttcgatacc gtctatggca
      841 cgccgccggt gagcggcttc accgggattc cctttgccag caccaccctc ggagccgaac
      901 agccgctgct gaactccgag ctcctgggct acggccgcga tccgctggcg cccatcaagg
      961 atgcggtcac ggcacatggc gatgtcgtcg tgccgctcga cgccgaggcc ttcttctggc
     1021 tgaaggcggc cttcggaacg ccgacggcca ccggcatgga agcgccgtac agccatgagt
     1081 tccagtcggg cgcatggagc ctgcccggca tgtcgatcga gaccggcatg ccggaggcac
     1141 cacgccacgc cgtgtactcg ggctgtgtcc tcgaccagtt cagctggcag atgcaacgct
     1201 cgggcctgct cacagctacc gcgcgactgg tggcgcaggg cgagacggtt gccaggacca
     1261 gcggcgcggg aacgccggcc gagctgaaac tgaagcgctt cgggcatttc aacggggcga
     1321 tcacgcgcaa cggctcggcg cttggcaacg tggtctcggc cgagatcacc tacgccaaca
     1381 acctcgaccg gatagaggcc atccgctcgg acggccgcat cgatggcgcg gacccgtcca
     1441 tggcggcgct gaccggccgg atcgaggtgc gcttcgccga ccagacgctg gtgacgcagg
     1501 cgatgaatgg cgaggcctgc gagttggaat tcgcctacag cctgctctcg ggcgagagtt
     1561 tcaccttcac tgtccacgcc gtctatctgc cgcgcccgcg gatcgagatt tccggaccgc
     1621 agcgcattca ggccagcttc gactggcagg ccgcccgcga cgccacgctg gggaggatgt
     1681 gcaccgccgt tctcgtcaac gacatcgagg actactgacc atgatccgtc tcgatctttt
     1741 cagcgcgccg aaatggctcg atcttggggc tggcctgcgc cggcacgtct tgcccgtcat
     1801 caccgccacc atggtcgccc cgccgggcgg caatcctgta tccggtcctg agggcgggcc
     1861 gcgggctggc gctgaggctt ctgaaccggc gcggcctgcg ctgacgaggg gcaggcgtgc
     1921 cgtcgcccgc ccggcacgtc tgcgaagcac cggatcaatc gtcgtcatcc ccgcgcaggc
     1981 cgcggatgcg acggcgcccg tcgtcatcgt catcatcccg ccagacacgg cccccgcggc
     2041 ggcggccatc gttgtcatcg tcaccgcggc cgtggtaaag acgatggcgc aggcgactgt
     2101 catcatcgtc gtcgtcatgg acctagccgg tctgggacag gatgaggcgg ttcaggctcc
     2161 gttcggccgg atcggcaagg gcggtggcag ggacgacagc gcttgccagc agcgcggcaa
     2221 caattgcgac tttcatgatc tgcatgatct gcatgatctg ctcctgttcc aaggcggtgg
     2281 cttcggcgct gcagaagtat cacgcggcag gacggcggtt attcccggcc cccggcccct
     2341 gcctgcggaa agcacgccga tagggcgcca aggcaggacg gcaggacggc agggatttca
     2401 gcgccgctgc gtcagcagcg ccgcctcttc ttcggggcca agcggcgtgc ccgcgccgct
     2461 ttcggccagg aaggcgtcaa gcgccttgat cccgcccgag gccgggacat agctatccgc
     2521 tccggtcatg ctcatggcga aacgctgcga ccagccgtcg tcttcgcggc tggcggccat
     2581 cggggtcgcg gttccgccgg aatgggtctc atattcacgg cagaacgcgt cgcgcgccat
     2641 catgaacgag gcgatcatca cgacgctttc cccccggcaa ctcgcggctc tcccccaagg
     2701 caaggtcgtc gagcgcggca agctgcgctt cggacagccc gggcgccggg ccgccccact
     2761 gccacaagcc aagcccgata accgccgatg caagtgccgc ggcggtctcg cccagcgggc
     2821 ggcggtcgag attggtcggc acgggggcgg accgggcttg gggaaaaggc gtggcggcgg
     2881 gtacggtccc ggcggcccga atgcgcgcga tcggggccgt gtcgttggcc gggggatgtg
     2941 gcgcggccgc cgcctcccgc agaacgcgcc ggctttcgat gaagacccgc agctgcgcct
     3001 gcaaccgggg gtcccttgcc agcgcggcct cgacctcgcg cgaataatcg gcttccagtt
     3061 catcatcggc gaaggccata aggatctcga cagtgatctg catccgcggc tcctcggcaa
     3121 acactggggt caaatgggca tacgcatggg cgctcatctt attcacagct tttcggccag
     3181 gggcagtcgg gcacgggaca ggcggctcat caccgtgccg cgcgggatgc ccggaacctc
     3241 ggccgcctcg gcagagctga gttcatggat acccacgagt tccagcacct cgcactgctc
     3301 gaccggcagt tcctgcatcg cggctgtccg tcgcctgcag catcagccgc ccctcgatgc
     3361 cgctgtcgcc ctggacgggc agggcctcgg ggatctcgaa aacatcgacc tcggcgccgc
     3421 gcgtccgccg ccggcgcgtc aggtctgtga aggcgttgcg catgatgcgg aacagtcatg
     3481 gccccagccg cgcggcgggg tcgtagcggt cggctgccag gatcgcgcgc tcgacggtgg
     3541 tctgcaccag atcgtcggct acatccgcgc gccgggccag cgacagtgca tagagggtcg
     3601 cagcgggggc cgcagccgga tcagcgcttc gccgaacgcc gcatccatca cactctccga
     3661 accggccgct tgaacatcgg gaagatttgc cgtccccagc cgtagttgcc cgtgaatgcg
     3721 agcaaagagg caagttcatg cgcatgctcc tgttgatgct gctggccgcg accatggcgc
     3781 tgacggttca gccgcgtgtg gatgcagaag ggctatggct ggtggccccg gccttcgcgg
     3841 acgacgacga cgggccgcgc cggcgttcgg cggcacccgc gcgtccaatc ccgctgccgc
     3901 agcgcgccga gaacgaaatc ctcgcccgcg gcctctccga tcagggcctc gcggcgctgc
     3961 agcatgggga tttcgccctt ctggaacaag gcgtccttgg gggtggcgac agtatcgccc
     4021 gccttcgcaa gcccacgcgc ctgaccatgg acgaggcgct ggccgccgtc cgccagcttg
     4081 tgcccgcggg gcgcagcgac ttcaatcatt tctaccgcac ggaacaggcg gaagcctgca
     4141 aggggatcga ctgccccgcg cggcgggccg ctgccgcgca tcggcatggt cgataccggg
     4201 ctgaaccccg ggcacgaggc gctgtcggag gcccgcatcc acctgcaccg ggtcgaggac
     4261 gagaacccgc cctcggacct gctgcacggg cacggcagtc gcctcgctgc tgatgggcga
     4321 cccggacagc cggacgccgg gccttgtccc gcaggtcgag ctggccgccg tggacagctt
     4381 tcatcgcgcc ggacaggacc agcgcaccga cgccttcgcg ctgatccggg cgcaggacta
     4441 ccttgagcag caggaggccc ggatcgtcaa cctgtcgctg gccggccctg caaacgcggc
     4501 gcttgaggcg caggtcgcag gcatggcgca ggctggcatg gtcctgatcg cggcggcagg
     4561 caacatgggt ccctccgcgc cgccgatcta tcccgcggcc tacccccagg tcatcgcggt
     4621 gacggccgtg gaccgcgacc gcggggtttg tcgccgcgcc gaccgcagcc cgtatatcga
     4681 ctttgccgcg cccggcgtgg atgtctggac cgccgcctcg gtccgggggg cgcacgaaga
     4741 tcggcacgtc ctaggccgcg ccctttgtca gcgccgccgc cgcgctgctg ctgcaggccg
     4801 agcgttctct gacgcgggcc gaggtccggg cgcgtctggt cgggcaggcc cgcaacctgg
     4861 gcgccgagga acgcggcgac atcttcggct ggggcctgct cgcgccgccg ggggatgccc
     4921 gtgaggacac cccctgcccc ggattggcgg gtaggcacgg cccgccgccg cggctatcgt
     4981 tccctcatcg gcaggatgaa cagcacagga aaggtcaggc catgagcaag cgcgccgttg
     5041 tggtgatcga tatccagaac gactattttc cggacgggaa atacgaactc gtcggtatcg
     5101 agaaggccgc gtcgaacgcc gcccgggtga tcgacgcggc ccgcaaaaag ggcgaccgcg
     5161 tcatccatgt ccggcacatc ttccccagcg acgatgcgcc cttcttcacc cccgattccg
     5221 agggcagcga gatcaacccc gcagtctcgc cgcaggaggg cgagaccgtg gtcgtgaaga
     5281 accatcccaa cccctttctc aagaccgatc tcaagaagat ccttgacgac ggcgggatcg
     5341 aggaggtcgt ggtcgtcggc gcgatgagcc atatgtgcat cgacgccacc acgcgggcgg
     5401 ccagcgacta tggctacagg acaacggtgg tgcaggacgc ctgcgcgacg cgggatctcg
     5461 aattcggcga tgtgtcggtc ccggcggcct cggtccatgc cgcgatgatg tccgcgctcg
     5521 gcttcgccta tgcgacgatc accgataccg acagctacgt ccgccagtag ctgcgaggtt
     5581 gcggccgggt cgaaggacac cggaagcggc gcaacagccg ttcaaggccc ggctcaggaa
     5641 ccggcacccc acgggcgcag gttcctgacc ctgaccgcgc gaaggcacgg gccagtccgc
     5701 cgttgtcccg gcgacagttg acgggcaggc ccgtgcgcaa gggctgcggc ctgccgctca
     5761 gcgggcagcg cgccgggccg cccgttccag cgcatcaagg aagcgcgacc tgtcggcctt
     5821 ggtgaaccct cgcccatgcc cctgcctgaa gggatcggcg gcgcgcagat cggccatcag
     5881 gtcgcgcgtg gcaagggcat tgccgatgtt tccggaattc agcgcctctc catcatgcct
     5941 gaggacctct gcccccgcgg ccacgcatct tgacgccagc gggatgtcgc cggtgatgac
     6001 cacatctccc ggaccggcac gttcggcgat ccacttgtcg gcctcgtccg ggccttccgg
     6061 cacgatcacg gtttccacaa gagggttggc cgagggcctg atgccgccgt tcgagacgat
     6121 caggacgcgc agcctgtgcc gggtggcgac acgctcgatc tcggccttca ccgggcaggc
     6181 gtcggcatcc acgtagatcg gcatggggaa tgacctttcc tgagctgagc agattccggc
     6241 gtcgccggtt cgcgccctga tgatggcaga tggaccggga tcctgcctgc cgcaagcggc
     6301 gccacggcga tcaggcgatc cgtaggaggc tggggatgga ctgctctgcc atcagaaaca
     6361 ggacggcgtc ttccatccgg ctctgttcct tatccgtttg atgcaagtcg ctgcagagaa
     6421 atccagcaag accgttcggc gaatcgtcct cacgatgccg ttcccgccgg cagtcggaat
     6481 ctccacgctg acgggatgcc aggcatcctg acccggcgcc tgataaggca agggaagatt
     6541 gatcttcgac ggcctgttcg ccgtcacggg ccatcctgcg gcgcactcgg caacccccgg
     6601 aacaaggatg gccgcctgct tcgcaccgcc cgctggccgc agcaggaaat cgcatccggc
     6661 acagggccgc caccggatcg cgagtcctgt cgctggacgg tggcgtgacc gcacacaccc
     6721 gccgttccct gcacccccgc gcggccagcg ttcttccacc agcctgtcgg ctctggcagg
     6781 ctggtcatgg ggttggcacc catggttctg tggcctttct tcgtcatgcc gccgggtcga
     6841 tcccgcgtcc cggcccccaa aggaggatgt ggtgatcaag accgagcctg cacgcccgtc
     6901 gcgctctgcc tttctgggcg agctgttcga gcagttgacc gaacgcggcc ggcgcctgct
     6961 cggccggcgc gatggggatc gcgtggtcga ggccctcgac ctttccgaac tggccgaact
     7021 gctgctgtcg cggcgcggcg aggcctcggg ggtggcgctg gcgcgggcgc tgctgtcggc
     7081 cttcgagcag gcggacgaaa acgcgcggct tgccttcctg cagaccctcg cccaccgctt
     7141 cgggccggac ctggacgcgg ttcaggcggc gctggccgcg gtgcaggccg aacccgcgtc
     7201 cgccgaggcc gttgaggcgt tgcatatcgt ggccgaaccg cgccggcagg aactgctgcg
     7261 gcggctgaac ctcgcgcccg gcggcaccgc cgcgctggtc cgcatgcgcg aggaactgct
     7321 gcgccatctc cgcgaccatc ccgaactgcg ccgggtggac agcgacttcg cgcatctttt
     7381 cgcctcgtgg ttcaaccgcg gcttcctggt gctgcgccat atcgactgga ccacgcctgc
     7441 caatatcctg gcgaagatca tccgctacga ggccgtccac gagatccgca actgggacga
     7501 cttgcgcaac cgcctggaac ccaccgaccg gcgctgctac gcgttctttc acccgcaact
     7561 ggcggacgag ccgctgatct tcgtcgaggt ggcgctgacc gaggcgatcc ccgacaacgt
     7621 ggcatcgctg ctggcgctcg accgccaacc gatcgaggcg gaacgggcca ccacggcggt
     7681 gttctattcg atctcgaaca cccagcgggg cttggcgggc gtgtccttcg gcaacctcct
     7741 gatcaagcag gtggtcgagg acctcaaggc cgagctgccc gacatccgca gcttcgtcac
     7801 cctgtcgcct gttccgggct ttgcggcttg gctcgcgcag cagcgcgacg acgcggcctc
     7861 cgacctgctg accccggccc agcgcgaggc cttcgccctt ctgaacaggc ccggctggca
     7921 tggggacgcg caggcggtgg aaagcctgcg tgcgccgctt ctggccgccg ccgccaccta
     7981 tttcctgagc gcgcgcgatg cgaagggccg gatgatcgac ccggtggcgc gcttccacct
     8041 cgggaatggg gcgcggctgg aacggctgaa cttcctgggg gacctttccc ccaatggtct
     8101 gcggcaatcg cacgggctga tggtcaacta cctttacgac ctcgaccgga tcgaggcgaa
     8161 ccacgaggcc tttgccgaac gcagcaccgt cgccgcctcg ggcgcggtgc aacgcgccct
     8221 gcccgcccca tcatcctgac atcacctgcc ggagcctgcc atgaacctgt tcgagacgat
     8281 cacccagcgc gtggctgacc ccgccgccac cgccatcgag accccttcgg gcgagcacat
     8341 cgcctatgcc gacctgatcg accgcatcgg acgcatggcg gatgcgctgg tcgatctggg
     8401 cgtcgccccc ggcgaccgtg tggccgtgca ggtggaaaag tcggtcgagg cgatcatcct
     8461 ttatctcgcc accgtgcggg cgggcgcggt cttcctgccg ctgaacaccg gctacacccc
     8521 ggccgaggtg gactacttcc tgaccgacgc cgagccgcgg atcttcgtct gcgatcctgt
     8581 ccgggaagag gcgctgcggc cgctggccga gaccgccggc gcccgcgtcc tgacgctgga
     8641 cgccgcgggc cggggcagcc tggccgacgc ggctgccggc atggccgggg atttcgccac
     8701 cgtgccccgc gcggacgacg accttgcggc gctgctttac acttcgggca ccacggggcg
     8761 gtccaagggg gcgatgctca gccacggcaa cctcgcctcg aactcgctgg cgctggtcga
     8821 ggcctggcgc ttttcggcca gcgacgtgct gatccacgcg ctgccgatct tccacaccca
     8881 cggtctgttc gtggccacca acgtggtgct gctgtccggc gcctcgatga tcttcctgcc
     8941 gaagttcgac cccgaccgga tcttcgcggc gatgccgcgg gcgaccgtgc tgatgggggt
     9001 gccgaccttc tacacccgcc ttctggaaga ccggcggctg gacagggaaa cgacgcaggg
     9061 gatgcggctg ttcatttccg gctcggctcc cctgctggcc gacacccacc gcgcatggca
     9121 ggcgcggatc ggccacgcca tcctcgaacg ctacggcatg accgaaacga acatgaacag
     9181 ctcgaaccct tacaacggcg agcggatcgc cggcaccgtg ggccagccgc taccgggggt
     9241 cgagatcatc gtcaccgacc cggaaaccgg cgcggaactg ccggggggcg agatcggcat
     9301 gatcgaggtg cgcggcccca atgtcttcca aggctactgg cggatgcctg aaaagacggc
     9361 ggccgagttg cgcctgaacg gcttcttcat caccggcgac ctcggccgct tcgacgagcg
     9421 cggctacctg cacatcgtcg ggcgcggcaa ggacctgatc atcaccggcg gctacaacgt
     9481 ctatcccaag gagatcgaga ccgagatcga cgccctgccc ggcgtgaccg aatcggccgt
     9541 catcggcctg ccgcaccgcg acttcggcga aggcgtcacc gcggtcgtcg ttccggccgg
     9601 cctcccggcg ctgaccgagg ccgatgtcct gcacccgctg gaatcgcggc tggcgaagtt
     9661 caagctgccc aagcgcgtgg tctttgtcga ggaactgccc cgcaacacca tgggcaaggt
     9721 ccagaagaac ctgctgcgcg accgcttcgc ggacctttac cgcccgtgac cggcgcatcc
     9781 tgcaacggca aggcagcgcc cctgccttgc cgccgccgtg gcatggcttc gcggggattg
     9841 cagtatcgct ttcgggcggc agtccccgcg ttccccggcg cgacgccgcc acgcgcggat
     9901 gaagcctgcg gaaccttcgg ccaccttgcc gctttccgtc cgtgcatcct tgccgcatat
     9961 tctggatcag atgtgcgaca gcaaaaacgg cgacggttgg atggatgaag agttcatgcg
    10021 ggacgcggcg aagcccatcg actggcgcag cgccgtcgat ctgcggctgg cagagattgc
    10081 ccgagggttc gggcgcgcct cgcccgatct ggggcgggcg atgtcggatg cggtgcttgc
    10141 acccggcaag cgcttccgcg cgatggtcct gctgatcgcg ggcgaggcga ccggcggcgt
    10201 caggccagcg ctgatcgacg cggcctgtgc gatcgagctg gtgcataccg cctctctcgt
    10261 cttcgacgac ctgccctgca tggatgacgc gcaggcgcgg cggggccgtc cgaccacgca
    10321 tctggtgcat ggcgaatgcc gtgcgatcct tgccggcatc gcgctggtga ccgaggcgat
    10381 gcggctgctt gccaccgccc gcgatgccga cgccgacacg cgcgcccgcc ttgtggcggt
    10441 gcttgccggc gcggtcggcc cgcaggggct ttgcgccggg caggacctcg acatccatgc
    10501 gtccaaggac gtggcgggca tccagaagga acaggacctc aagaccgggg cactgttcgt
    10561 tgccgggttc gagatgttcg gcctgctgca gcgcctgggt gcaagggaca tggagacgct
    10621 gtcggcgctg ggccggaccc ttggccgcgc cttccagtcc tacgacgatc ttcttgacgt
    10681 ccaggccgag gccggggcgc ttggcaagga caccggccgc gatgcgcatg gccatggacc
    10741 cgcgcgcggg gtgctggcgg tccgcagccc ggcgcaggcg caggcgcatt acgacgcgct
    10801 gcgcgcggaa ctggacctgc tgctgggaaa ttgcggcttc aacagcctgc cgctggcccg
    10861 gcatgtcggg cgcgtcctgc cgcgccgcgc catccgcgcc gcctgaggat cacgcgcgcg
    10921 ggcgggtcca caacccctcg cgcaaaggct tcggcggaag gacgcgcgat cggcccgcat
    10981 cccccagcgc gcgcaaggcc agccccgcct tggccgcacc cgaggtgccg atgcgctggc
    11041 ggtaggcttc cggcccgccc ttgcggatgc gggcgccgat cgcccgatag atccgcgccg
    11101 ccgccgcgat cgaccaggcg cagcgggcgg gcagcgccgg aaggcccgcg aaggccgagg
    11161 catagtaagg ttcggccgcg tccagcaggc gcaggatgac ggcgtaaagc tggggtgagg
    11221 gaatgtcgcc ctcgatggtg gcacctgcct cgtccagcca gtcgccgggc agatagactc
    11281 gcccgatccg ggcgtcatcg atgacgtcgc gggcgatgtt ggtcagttgg aacgccagcc
    11341 ccaggtcgca ggcgcggtcc agcaccgcct gatcccgcac ccccatgacg cgggccatca
    11401 tcacaccgac gacccccgcg acatggtagc tgtagtccag cgtgtcgttc agtgtccgat
    11461 acgcgcgccc ttcgacgtcc atggcgaagc cgtcgatcag gtccatgggc cagcggtcgg
    11521 gaaagtcgtg ccgccgcgcc accgcctgca gcgcagcgaa cggcggggtc atcggccccg
    11581 tgccgtgcag cgcctccagc gtctcggcct tgagccgcgc gagccgctcc tcaggatcgc
    11641 cgcccgcctg aggcgcgctg ccaagctcct gcccgtccac cacgtcgtcg gcatggcggc
    11701 accaggcgta aagcatgatc gtatcctcgc ggatgcccct aggcatcagc ttcgcggccg
    11761 ccgcgaagct ttgcgagcca gccgcgatgg cggcctgcga ttcggcgacc ggcgccgtca
    11821 tgccgcgccc gcgtcggcca gcatcacgcc tgcggtggcc ttggcggagc ccacgacccc
    11881 ggggatgccc gcgccgggat gggtgcccgc gccgacgatg tagaagttgc ggatactgcg
    11941 gtcgcggttg tggggccgga accaggcgga ttggcgcagg atcggctcga ccgagaaggc
    12001 gctgccgtga tgggcgttca gctccgacgc gaagtcggcg ggcgagaaga tgcgtttcac
    12061 ccgcaggttg gcgcgcaggt tggggatcag ccgctcctcg acgctggcga ggatgcggtc
    12121 ggcataagcc tcgccctcgg cggcccagtc gatcgccgcg cggccgagat gcgggacggg
    12181 ggcgaggacg taatgcgtgg acatccccgg cggcgcaagg ctgtcgtcgg tcacactggg
    12241 cgaatggagg tagagcgaga aatcctcggc gagcttcggt ccgcggaaga tctcgttcac
    12301 cagctcgcgg tagcgggggc cgaagaggat ggtgtgatgc gccagcccct cggggcgctg
    12361 cgacaggccg aagtggatca cgaacagcga catggaccag cgctggcgtt tcagcagcgc
    12421 ggccttggtc cgcccgcgcc gggtgccgcc cagaagatcg cgatagctgt gcatcacgtc
    12481 ggcattgctg gcgaccatgt cggcggtcag gcgggtgcca tccgccagcg tcacgccggt
    12541 ggcgcgagcg ccttcggtct cgatccgcgc caccttggcg ttcaggcgca gcgtgccgcc
    12601 aaggcgctgg aacagcgtgg ccatgccgga caccagcgca ttggtgccgc cttgcgcgaa
    12661 ccacacgccg ccgcgccgtt ccagcgcgtg gatcagcgcg taaatcgaac tggtcgagaa
    12721 tggattgccg cccaccagca gcgtgtgaaa ggaaaacgcc tgccgcagat gggggtcctt
    12781 gatgaagcgc gcgacgacgc tgtgaaccga gcgataggcc tccagccgca ccagcgcggg
    12841 ggcggcctga agcatctggc ccagcttgag gaagggcacg gtgccgagcc gcaggtagcc
    12901 ttcctgatag acctgttccg cataatcgtg gaaccggcgg tagccgtcga ggtcggcggg
    12961 gttgaaggca gcgatctcgc gctccagcgc gttgccgtcg ttgacgtagt cgaagcgttt
    13021 cccgtccggc cagagcagcc ggtagaaggg gttgaccggc agcagggtca cgtcgcgggc
    13081 catctcctgc ccagacagcg cccaaagctc gcgcagggaa tcgggatcag tgatgacggt
    13141 gggaccggcg tcgaagacat ggccttcctc gcgccagaca taggcgcggc cgccgggctt
    13201 gtcgcgggct tccagcagcg ttgtggcgat gcccgccgat tgcaggcgga tggcaagcgc
    13261 cagcccgccg aagccagcgc cgatgacgat ggcggtgcga ggagaggtca cgcggtttcc
    13321 ttcagcagcg gcgcttcgcg caggcagggc agcgcgtcgc ggatgggaat ggggggcttg
    13381 ccgctgacga tccgcagccg gtccagccgg gtcagctttc cggcgtagaa gcgttcgatc
    13441 agcggctcgg gcaggcgata gaagcgggac aggacgcggt ggcggcggtc cggcgggcag
    13501 ccgcggaaca gcatccgatt gagcaggcgc aggaagcggt catcgcccgc gcggtccagc
    13561 gcatgggcgc agacagcgga gaagacctcg gccgtggtcg gccccgccgc cgcgaccaca
    13621 tccgccacct gcgcggcgac gggcagggaa tagccggtga cgggatggaa caggcccgcg
    13681 cgcagaccca cgggagctgg gccgccctgc gcctccgccc acagcgcggc ggcgtcatgg
    13741 gccagcgcga tgggcaggac gccgcgctcg cggcggacct cgcggccggt ccagcccttg
    13801 tcgctggcat aatcggcgat ggcgcagacg atggcctcct cgtccagcgt ggcgccatcg
    13861 ctgtagcgag tgtcctcaat cagcaggcgc gtgggggaaa agggcagcag gtagacgaag
    13921 cggtagccgt cctgctgggg caccgtcgcg tccatgatca gcgggcgggt gacgccatgg
    13981 ggggtgttca tctcgaactc cagccccacg aacttctggt agccggtgac gagatggcgc
    14041 gaggaccgcg cgccgcgccc gtcaatgacg cagggcgcct cgatccgttc ggatccgagg
    14101 gtcgcgccgg tagcgtccag cgccgtgatc ccggcattcc agcgaagggt gacgccgggc
    14161 gtgtccgcca gcagccgcgc cagccctgcg ccgtcaagcg aggcataacc agcccgcaac
    14221 acgcgggaat ggtcgggaaa gcggacctcc tgccccggcc agcggcagcg gatcgcgggg
    14281 gaaaggcggc ggtgccaggg cagccgcaga tccgggtcgt ggaaggacca ggtatgcgca
    14341 tccgacggac tcggcgcgcg gtcgagcatc aggatgcgcg cgccgggccg cgcctcggcc
    14401 acggcaagcg cgatcagcgc attggcaagg cccgcaccgg caaggatgag gtccggcgtc
    14461 atgcggcaag cctgcactga agctgcgcct cgaccagatc ggcggcccca gtggcaccgc
    14521 ctgccgcgcg gatttcagcg gcgggccggg caagggccaa gcggtgggac gggtcggaca
    14581 acaccgcccc cagcgcctcg cggattgcgg cacgggtggc gcggcgcagg ggcaccactc
    14641 gggccgcgcc atgaaaggcc agccgcgcgg cggtcgcggg ctgctcgaat gccaggggga
    14701 tcgcgaccat cggcacctcg gcccccgcgc agtccagcac cgtgttcagc ccggcatggg
    14761 tcacgcaggc atcagcgcgg gccagcactg cccgctgcgg aaagaagtcg cgcaccagcg
    14821 gcgcaccggg caacgcccgc gcctcggcct cggtcagccc gccgcaatgg gcaagaacaa
    14881 ggaacacgcc cagatcctcg gccgccccgg cgatggcagc cagaagtccc cgccggttcc
    14941 cttgcagcgt gccgagcgag gcgaaaacaa ggggccggcc gccggtgtcg atctcgaact
    15001 cgcctgccgc atcgtcccgc agcggaccga ccgcccgtgc gccccgcccc ggcgcatggg
    15061 ggaagtccag cgagggcacc aattgccgca ggtccagatc gggcgagatc cattcgtcga
    15121 tgcgccgccg cagcggcagg ccatgcgcgc ggcagcccgc ggccagggcg cgggactgca
    15181 gcatcatcaa cgcgtcggcc acgcgccagc caccccggtt gcgcttgcgg cccgcctttc
    15241 ccgcaagaaa gggccagtcc acgaagggcg gcgggatcgc ctcgtcgcgg tccagcggca
    15301 gggccgaggc gagggtcacg cgcgggatgc ccgccgcttc ggcggcaagg ctggcgcccg
    15361 gttcggcctg atcggcgacg accagatcgg gggaaagccg ccccagcgcc cgcggcccgc
    15421 gccggacgaa gctgcgggtc gccgcggcgg tggccagcag cgtgcggacc agccccgcgc
    15481 cgcgcaggtc agggtcgcag agcccgaggc tgtcaaaccc aagaccctcg cgcgccgcca
    15541 gcgggccaag cccctcgccc cccaccatcc ggcaatcatg tccccgcgcc gccagcctgc
    15601 gggccagcgc gccatggacg gcggcgtggc ttgacagggc gggaaggcag aaggcgatgc
    15661 gggccatgca ggctcagtct tcgccgcggt ccgggcgcca ggcgtcccgg tgccgggact
    15721 gccgccgtgc cagcacgccc gaggtcttca gccgcgcctt gagatcgtcc accggcggcg
    15781 catagacaaa gccgaaggac acgcagtcgt cgcgcccctc gaccgcgtga tgcagccgat
    15841 gcgcctggta aagcctgcgg aaatagccgc gccggggaat atagcggaat ggccagcgct
    15901 gatgcacgag gccatcgtgg acgacgaaat agatcacgcc atagacgctc atccccacgg
    15961 cgacccacca catccacggc caccagcggc tgccgatgac gaacagcagg atcgagagcg
    16021 cggcgaagat aacggcgtaa aggtcgttct tctcgaaggg gccgtgggtt tcctcgtggt
    16081 gcgacttgtg ccagccccag cccaaaggac cgtgcatgat ccagcggtgg acggaatagg
    16141 ccacgccctc catcaccgcg acggtcagga cgacgatcag gatcgggcca aggacgctca
    16201 tgccccgtcc cttcgagtcg agggcagccg ccaccatggc actgcggggt gcaggtggtg
    16261 ttcatggtga tagccgccaa agtggaaaca ggtcagcagc gacacagggt cgctgacaat
    16321 ggtggaccgc gcgttgtggc ggtcgggaaa gtcgccatgg cccggccggt gcggcagcca
    16381 ggttccgaaa acgaaaagct gcatcgacgc aaggatcgag ggcaccgacc agaaggccac
    16441 atagggccag cggcttccaa ggatcagggc gtaaagcatt accgtccctc ccagaaccca
    16501 gaactcccgc cagccgaaat aggtgcggac aaaatcggca taccagcgga ccggcccgcc
    16561 atggccgaag tcggggtcgt cgtcggtgcc cgcatgacgg tggtgggcca tgtgcttgac
    16621 gatcagcttg cgccaggaaa acccggcgta aagcatcagc gccagcccgc cgacagcggc
    16681 gttgaggctc gggcggccgg gtgccaccgc gccgtgcatg gcgtcatggg cgacgatgaa
    16741 caggcccacg gaaagccagg tcagtccgat caggcacaaa cccgccagca gcggatgggc
    16801 cgtggcgtcc agatgccaga cggcgaagat gtgcaaggcc agccatgcgc cgatcacccc
    16861 tgccgcaagg gtcatgccga tcaggctggt ggcaaggggt cgtcgcagcg cctgtggcaa
    16921 gcgggttctt ccttcttcat cctgtaacgc ctgtgccagg atatagcagc acgagggccg
    16981 cttccagtag tcacctgccg caggtctcac gcaaggggcg cgtggcgcag tgcctcaaga
    17041 tcgcgcgagc cggtgcagaa catggcaatg cgaagctgct cgatgacctc ggacagatac
    17101 gcggccagcg cctcggcccc ctcacgcgcg gcgggcagcg cgcccgccgc ctgccccgcc
    17161 agatccgcgc ccaagcggat cgcgcgggcc acgtccagcc cgtggcggat gccgcccgag
    17221 gcgatcagca ccgtgcccgg ccacatgatc ggggccatcg ctgaaaccgc ctcggccgtc
    17281 gggatgcccc agtcgaagaa gggcgcggcg atgcggcgca ggcggtcgcc gccgcgctcg
    17341 gcctcgaccc gcgcccagct tgtgccgccg acccccgcca cgtcgaggat cgtgacgcct
    17401 gcatccatga gccgccgtcc gacatcggcc gacaggccgg cgcccacctc cttgacgcca
    17461 aggggcacgg gcagggcgcg ggccagcgcc tcgatcctcg gcagcaggtc cgaaaagtcc
    17521 cgatcgccgc cgggctggat cgcctcctgc agcgggttga gatgcagcat cagggcatcc
    17581 gcttccagca tctcgaccgc gcggcgcgcc tcgtccgcgc ccatcccgcg ccgcagttgc
    17641 accgccccca gattgccgag gatcggcaca tccggcgccc gagcccgcaa ctcggggcca
    17701 agcccgcccg ccccgcgtcc ctcgatggcg atgcgctgcg atccgaccgc aagcgccaag
    17761 cccaaggcgc cgcaggcctc ggcgatggac aggttgatgc gggcggcccc gggcgtgccg
    17821 ccggtcatgg ccgacaccat cagcggcgcg gacaggcggc ggccgagaaa gcgcgtggcg
    17881 gtgtcgatgg cgtcatagtc cagttccggc aacgcattgt gcaggaaatg cacgttgtcg
    17941 aagccggttg cgcgcgaaag ctggataccc tttcccgcgc cgacgatcgc cagatgctcg
    18001 gacttgcggc ccttgatctc gttcatggtc ccccagcacc ggctagcctg cgcgataggc
    18061 gcgcaggaaa ccctccacca catggttcag gaacgcctcg ccgtccagcg gatagtcccg
    18121 cgcgccgcca agctgcccct ggtgcagcgc ccccagcagc aggggtgagg caagcgcaag
    18181 cgccgccatg cgggtgtcga ccgcacgcat ctggccgcgg gcgacatggg catccagccg
    18241 ctcggtgagg gcaaggacga aaggctcgaa catgctgtgg atgaaggcgg ggccgagcag
    18301 atcgttccgc atcccctcga ccatgcccat cgccagcgca tccgccaccc cgtgttgcgt
    18361 cagcgcccgc caggccatgg ccgccgcgtc gcggaccgag gcgtcaagct ggggccccgc
    18421 ctgccgggta gccgtgaact gcccctgccc gcgccggccc gaatcggcaa agaccgccac
    18481 cacgatgtcg tcgcgcttgc cgaagtaatg gttcagggtg gacacgctgc agcctgcagc
    18541 cgtcgcgagt tcgcgcagcg ttggccggcc cgcgccgcgc agcagcaggc gtccccgcaa
    18601 ccgcgccagc agctcgccgc gccgttcgtc gaagcgtgcg ttgcggacgc ccttggacct
    18661 cacgtcccct cgcttcctgc cgcggatcgc ggcggtcttc catcggccct cagcgcaata
    18721 tcatcctggc cgtgccaagc acaaatccgt cgtggatcat cagggcgacg gcgatctcgg
    18781 ccagtccgcc gcccgcgatg accagccagc gcgggaagtt atgcgccgca agaaagccca
    18841 aggcaacaaa gcccgtgtcg ctcagggcgt tcacgatgct gtcgccctga tagacatcga
    18901 taccatcggg gtcgttgaac agtgaaatga cccaaggggt gttctcgacg atctcccaca
    18961 ggccgctgca ggcgatcacc agcagcaggc gggttccgac cggccagccg ggccgcagcc
    19021 gccgtgcaag aaagaacagc gccgcccccg agatcgcgtg aagcgccgaa tagaagtcgg
    19081 tcagatgctg cgagttgtgg gacagggcgg tgctgggatt ccaccagtag agcggcacgt
    19141 tttccggcag aaattcgcgg cccaggaaca gcagccacag caccactgcg gcattgatca
    19201 gcaggatgcc cagtgccagc gtcagcagcg gctgcccgcc acgaaacgca agcgagcccc
    19261 ccacgggccg gggcgggatc atgtccgcgg ggcggttcat gtcatcgaag tgcaaagggg
    19321 aacgctctcc ttgctggctg cgggggctgc gcctgcctgt tactcggacc gcaggatcgc
    19381 ggcgggtttg accgtcaacg cccgcagcgc gaaggccagt tccgccgcaa gcgtcgcaat
    19441 cacgccaccg gcgaccagaa tgacggcgct ggaccagatc acccggtggt cggtgtccag
    19501 cacaaaatgc gccaccgccc atccccccac ggccccggcc gcgatcgcgg cgatgccggc
    19561 gatcagcccc agcaacgccg ctcgcagcgc aaagctgcgc aggatcagcc cccggctggc
    19621 ccccagcgtc ttgaggatcg cggcctcgta gcggcgcgcc cgcgcggcgg ccagcgccgt
    19681 gccgatcagc acggcgaagc cggtgaccag cgtagccgcc gcaccccagc gcacggccgc
    19741 gccgatgccg gccagcagcc ccgcgacccg ctcgatggcc tcgcccacgg ggatggcggt
    19801 gacattgggc cagcggtcgc cgatctcgcg caggatggcg gtctcggcct ccggcccggc
    19861 atagacggtg gcgatccagg tgtgcggcgc gccctgcagc gcggcggggt tcatcgacat
    19921 gacgaagccg atacccgcgt tcctgaaatc cacctgccgg aacgaggcga tggtgccggt
    19981 gatgtcgcgc cccaggacat tgacggtcag ggtgtcgccc agcgacaggc cgatctcggc
    20041 ggcttcttcg gcggaaaagc tgataagggg cgggccgtcg taaccggcgg gccaccactc
    20101 gcctgccgtg atcgtcgtgc gcgagggcgg gttgtcggaa taggtcaggc cgcggtcccc
    20161 ccggacgacc cagtgatcgc ccgccacctc ggtcgccggg cggccgttga tccgggtgac
    20221 gacgccccgc agcatcggcg cggcctcgac gcggctgacg ccgggattgc cgcgggcaag
    20281 ggtgaggaag tccccgatct ggtcgggctg cacatcgacg aagaagaagg acggcgcgac
    20341 gcccggcatt tccgattcga tcgcgcggcg cagggtgccg tcgatctggc ccaccaccgc
    20401 cagcaccgcg aggccaagtc caagcgacag cacgacgccc gtggcatccc cccgatgcgt
    20461 cctgagcgcc cccagcgcca gccgcagggc cgggcgccgg cgggcaagcg gcatcagtcc
    20521 gcctgccagc ggcgccgcca gcagcgcgac aaccgccagc agcgccagcg tgccggcaac
    20581 cccgcccagc gtccagagcg tcagccgcca gttgcccgag aaagccgccg ccgccagcag
    20641 gaacagcccc gcaagggcgg tgatcattgc cagatacctg ggccgcggca ccctgcgacc
    20701 cgcgtccaca gccgagcgga acaagaccgc cgcgcgggtg tcggccgcca gggccagcgg
    20761 ccacagcgca aaggcaaggg cggccaatgc gccgtaaagc gcagcctcgg ccagcggtcc
    20821 gggaaagacg ccgaaggtcg ccggcatcgg caggcgcgct tcgatcaccg gggccagcag
    20881 cagcggcagc gcggcgccca gcgccagccc cagcatgatc ccgagtgcgg tcatcaaccc
    20941 aatctggatc aggtaggtca ggaatatcac gcggcggctg gcgcccaggg acttgagcgt
    21001 ggcgatcacc ggcagcttcg cgtccagcca tgcgcggacg gcggccgaga cgccgacccc
    21061 gccaaccgca aggcccgaca gaccgatcag gatcaggaag gcccccagcc ggtccacgaa
    21121 gcccgaaagc cccggcgccc cgtcccgcgc atcgcgccag cgggcgcccg cgccctccag
    21181 cgcagccatc gcctgccccc gggcggtgcc gaggtcggtg ccgggaggca gcagcagccg
    21241 gtattgcgcc tcgaacagcg tccccggccc cagcagtccg ctttgcgcca aatccgacgt
    21301 gcggacgatg gtgatgggac caagcgcgag gctttccccc gcattgtcgg ggaagctgtc
    21361 gaggatcgcc gtcagcgtga acgcctgttc gcccagccgg aagccgtcgc cgggggaaag
    21421 gccgaggcgc tcggccagca cccgttccat caccgcgccg ggatcgccgc ctgaagaaag
    21481 cgcctgatcc caagagatcg gcggggacag ccggacagcg ccgaccagcg gataggcgtc
    21541 gtccaccgcc ttcacctgcg tcagggcgcg ctcgctctgc ccgtggcgca ggacggtcgc
    21601 catggaccgg aactcggctg tctcggacac cgccgaggcg atccggtcca gcgccgcgcg
    21661 ctcggcaccg gtggcgaagc ggtaggtcag ctcgacctcg gcatcgcctc ccagcagcgc
    21721 ggcgccgttg cgcgccagcc ccgcctcgat cgaggcgcgc acggttccga ccgccgccag
    21781 cgccgccacc gccagcgcaa ggcaggtcag gaagatgcgg aagccggcaa gcccgccccg
    21841 catctcgcgg cgtgcaaggg tccaggcgag gcgcagggtc atgccgcctg ctccagccgg
    21901 ccgtcgcgca ggcggatgat gcgggcgcag cgcgcggcga tttccggcgc gtgcgtcacc
    21961 atcaccagcg tcgtgccgct gtcccgcacc atcccgaaca ggaggtccgc gatctgcgcg
    22021 ccggtcgtct cgtcgaggtt gcccgtcggc tcgtccgcca gcaggatcgc gggacgcggg
    22081 gccagggcgc gggccagcgc gacccgctgc tgctcgcccc cggaaagctg cgagggataa
    22141 tgatgcgcgc gcccggcaag acccacggct gcaagccctt cgcgcgcccg cgctgcggca
    22201 tcgggcgcat gggcaagctc aagcgggaca gccacgtttt ccagcgcggt catggtcggg
    22261 atcaggtgaa agctctggaa gacgatgccc atgtggtcgc ggcggaagcg ggccagcgcg
    22321 tcctcgccca tcgcggtcag gtcgtggccc agcgcgcgga cccgcccgcc cgtcgcctgt
    22381 tccagcccgc ccatcagcat cagcagcgac gacttgcccg acccggacgg cccgaccagc
    22441 ccgaccgtct cacccttttc cacggcaagg gtgatgccgt gcaggatctc gaccggaccg
    22501 gcgctggaac gcagggtcag gcgcacatca tcaagggaca ggaccgggtc cggcatcgcg
    22561 cgtctccatt caagggtccg cgctggggcg gcgaatgtgc aacgttgtga ccggcgtgcc
    22621 ggtgccatcg cctcacggcg acattatgtc cgggcgaaac ggaggactgc aatgcttgca
    22681 cgcatgatcg ggatcacgct tctgtctgcc ctgcccgccg cggcagagcc ggtgacggta
    22741 gccgccttgg gggacagcct gacgcagggc tacggcctgc cgcaacagga agggctggtc
    22801 ccgcaactgc aggcgtggct acgggaacgg ggggccgagg tcacactggt caacgcgggc
    22861 gtgtcgggcg acaccacggc gggcgggctg tctcgcgtgg actggacgct gacgcccgag
    22921 gtggggggca tgatcgtggc gctgggcggc aacgacctgc tgcgcgggat cgatccggcg
    22981 gtgagccgga agaacctttc cggcatcctc gacgccgcgc ggaaggccga ggtgcccgcg
    23041 atgctgatcg gcatcggcgc gcccgcgaat tacggggccg agttccagac ggcgttcaac
    23101 ggcgtttata ccgatctcgc gcaaagctac gaggtgccgc tgatcccgtc gatgctggac
    23161 gccatcgtgg cggcgcgcga cccgctgtcg ctgatgcagc cggacggcat ccacccgaac
    23221 gccgagggcg tccgggtgat cgtcgaaggc atcggcccgc aggtgctgca gttcgtggcc
    23281 gcccttggcg cctgcgaaca gggctgcacg gacggctagg ccgtcagaac gggctgtcgg
    23341 ggaagtagaa ggcttccgcg ttctcgggcg tgatgagctg gctgccgatg atgtagcggc
    23401 ccgccatcgg cgcgttcgat acgaaatgca gcgccgtcat ctcgatcgcc gaggagatca
    23461 gcgccggagg ataggtcacg ttcaccggca gttgcgggtc cttgtccatg atccgcttga
    23521 cgatgtcctt catgcccgcg ccgccgacga cgaccatctg gtccccacgc cccgcctggg
    23581 cgatggcctc cagcacgccc acggccatgt cgtcgtccgc cgcccagacc gcgttgattt
    23641 cagaatattt ggccaggtag tcctgcatca cgttgaaggc gtcgtcgcgg ttccagttgc
    23701 cgtgctgcat gtcgaggatt tccttgtcgg acccctcgag cgccgcctgg aaggcctcga
    23761 cccgctcgtt gtcgagcgtg gtcgggatgc cccgcagcac gacgatcttg gcgccggcgg
    23821 gcaggttgtc gcggaaatat tcgcccgcga cgcggccgaa ggcggtgttg tcgccggcga
    23881 catacaggtc ctcgatgcct tcctcggaca gcccccggtc cacgacggtc acgaacttgc
    23941 ccgccgcctt cacctgccgg accgggtcgg tcagcggctc ggattcgaag ggcagcacca
    24001 ccagcccgtc gatgttgcgg gtggccagca tgtcctcgat gtcggacacc tgcttggcgg
    24061 cgtcgccggc cgtcgccagc acgaattcga ggttcggata gacctcgccc agccgcttga
    24121 tcgtgtcctg agcgtgccag ttcagcccgc ccatgaagcc gtgggtggcc gaggggatcg
    24181 acacgccgat cacccgtttc tcggcctctt gcgcgaaggc ggcgcctgcc gccaacgaca
    24241 gcgccgcggc cgccagcggc agtttcagca gattgcgacg gatcattctt tcctccccag
    24301 gatggccgct attcggcgga ccgtttctct cgctgcaaga cgacggcgag cacgatgatg
    24361 acgccttgga tcgccccgtt cagatagggg ctgaccaggt ccgccagatt caggatgttg
    24421 tcgatgagcg acaggatcag gacgccgacc accgtgcccc ag
//
