LOCUS       NZ_AP024109            20639 bp    DNA     circular CON 10-NOV-2023
DEFINITION  Mesorhizobium sp. J8 chromosome, complete genome.
ACCESSION   NZ_AP024109
VERSION     NZ_AP024109.1
KEYWORDS    RefSeq.
SOURCE      Mesorhizobium sp. J8
  ORGANISM  Mesorhizobium sp. J8
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Phyllobacteriaceae; Mesorhizobium.
REFERENCE   1
  AUTHORS   Kusaba,I., Nakao,T., Maita,H., Sato,S., Chijiiwa,R., Yamada,E.,
            Arima,S., Kojoma,M., Ishimaru,K., Akashi,R. and Suzuki,A.
  TITLE     Mesorhizobium sp. J8 can establish symbiosis with Glycyrrhiza
            uralensis, increasing glycyrrhizin production
  JOURNAL   Plant Biotechnol. 38, 57-66 (2021)
  REMARK    DOI:10.5511/plantbiotechnology.20.1124a
REFERENCE   2  (bases 1 to 6690860)
  AUTHORS   Maita,H. and Sato,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2020) Contact:Shusei Sato Tohoku University,
            Department of Environmental Life Sciences, Graduate School of Life
            Sciences; 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/10/2023 07:29:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,439
            CDSs (total)                      :: 6,376
            Genes (coding)                    :: 6,302
            CDSs (with protein)               :: 6,302
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 48 of 74
            Pseudo Genes (incomplete)         :: 41 of 74
            Pseudo Genes (internal stop)      :: 12 of 74
            Pseudo Genes (multiple problems)  :: 21 of 74
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:17:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 933662
            Orig. end                         :: 954301
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024109.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="5"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20639
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10639](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10639
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     gene            107..2326
                     /locus_tag="MJ8_RS04420"
                     /old_locus_tag="MJ8_08800"
     CDS             107..2326
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ECH (12-215). E-value: 2.6e-46. Score:
                     149.9. Matches aSDomain: nrpspksdomains_MJ8_RS04420_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015319307.1"
                     /locus_tag="MJ8_RS04420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08800"
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /protein_id="WP_201413265.1"
                     /transl_table=11
                     /translation="MSYTNFTLDVDADGITLVTWDMPDRSMNVFTEEVMRELNAIVEKV
                     TADAAVKGVVITSGKDSFSGGADITMLQKMLATFAVDKEKDLEKATKALFENAGYMTGL
                     FRKIETSGKPWVSAINGTCMGGAFEMSLACHGRVAADSDKVKMALPEVKIGIFPGAGGT
                     QRVPRLTDQQQALQMLTSGQNLTPQKAKAMGLIHEIAEPKKLIETAKAMIRNGLKPVAP
                     WDEKGFKLPGGPVYSAAGANLWPPAIAILRRETYGNYPAAAAILKCVYEGLLVPFDTAL
                     RIEQRYFTEIMQSKEAAAMIRSLFLSLQELNKGARRPSGLPDTKFKKIGILGAGFMGAG
                     IAYVTAKAGIPVVLLDRDLPSAEKGKAHSDSLMADQIKKGRAKPEDKDKLLSLITPTAD
                     YADLAGCDLVVEAVFEDSSVKKDATEKAEAVLKSSAIFASNTSTIPITALAKNSARPKN
                     FIGIHFFSPVDKMMLVEIILGKKTGDKALAVAFDFVRAIKKTPIVVNDTRGFYVNRCVL
                     RYMSEAYKMLIEGVPAPMIENAAKAAGMPVGPLALTDETAVDLAQKIMKQTIRDLGEKA
                     VDPRQMALINTMVDTHGRFGRKNGKGFYDYPAKPAKKKLWPGLRDLYPQLKPEKVDYEE
                     LKQRLLVTIALEAARVMEEGIVTDPREADVGSILAFGFAPFTGGALSYIDGIGAKRFVK
                     IAKGLQKKYGAEFKAPKLLLDMAEKGETFYQRFDPYRKGEVREAA"
     aSDomain        143..751
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MJ8_RS04420_ECH.1"
                     /evalue="2.60E-46"
                     /label="MJ8_RS04420_ECH.1"
                     /locus_tag="MJ8_RS04420"
                     /protein_end="215"
                     /protein_start="12"
                     /score="149.9"
                     /tool="antismash"
                     /translation="DGITLVTWDMPDRSMNVFTEEVMRELNAIVEKVTADAAVKGVVIT
                     SGKDSFSGGADITMLQKMLATFAVDKEKDLEKATKALFENAGYMTGLFRKIETSGKPWV
                     SAINGTCMGGAFEMSLACHGRVAADSDKVKMALPEVKIGIFPGAGGTQRVPRLTDQQQA
                     LQMLTSGQNLTPQKAKAMGLIHEIAEPKKLIETAKAMIRN"
     gene            2336..2878
                     /locus_tag="MJ8_RS04425"
                     /old_locus_tag="MJ8_08810"
     CDS             2336..2878
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013897284.1"
                     /locus_tag="MJ8_RS04425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08810"
                     /product="thioesterase family protein"
                     /protein_id="WP_201413266.1"
                     /sec_met_domain="4HBT_2 (E-value: 4.2e-17, bitscore: 61.3,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVWGRMARTMATASSRGPYRVGEESRLAFRCLPIDIDFNLHLNN
                     ARYMMLADLGRIDIFLRIGLIALARKNGWAPMIGGLQVAYVREIRLWRRFEVVSSIETW
                     EGTSVIGRHRFVLDGGETAALILTTGGVYDRAGRRFLDIEEVVAALGRAAGPRPPTEAE
                     RTFMVSHRNLREQAKAA"
     gene            3177..3818
                     /locus_tag="MJ8_RS04430"
                     /old_locus_tag="MJ8_08820"
     CDS             3177..3818
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013897283.1"
                     /locus_tag="MJ8_RS04430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08820"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_095765907.1"
                     /transl_table=11
                     /translation="MLSHDRVWAAIDALAERYSLSASGLARRAGLDSTAFNKSKRLSSD
                     GRPRWPSTESLAKIIEATGASLEEFTGLVEGRSGASVAQHRSAVPLLGFAQAGAGGFFD
                     DAGYPAGQGWDLVELPARATETSYALQVQGDSMLPLYRNGDVLIVEPGAPTRKGDRVVV
                     KTTAGEVMAKVLDRQTMKSIVLVSLNPDHPDRDIPTRDIEWMARIVWASQ"
     gene            3828..4712
                     /locus_tag="MJ8_RS04435"
                     /old_locus_tag="MJ8_08830"
     CDS             3828..4712
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006199963.1"
                     /locus_tag="MJ8_RS04435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08830"
                     /product="thermonuclease family protein"
                     /protein_id="WP_201413267.1"
                     /transl_table=11
                     /translation="MRLLQTALAVLAVPVMAALVVAGGHAVKGHESAVTVDQIDPIADA
                     LPTGDNTLSASDAAQEPATSAIPAPAAPQPPKPAAHSRAIDPDVVAPPDLSDNELERVE
                     PRAPLSDLALAGPPKPPKTKMPSDWNGTKLFQPVATAAGLIESKGYAVAVSGVDVVKAD
                     ETCSDEGKSWACGARARTAFRAFLRGRAVACTVPPEGGRDTITAECHIGNQDIGQWLVE
                     NGWARAAQGGPYVEAENKARTARKGIFGPAPKLDGLPAVPAASGPAPVAPDSILPADGG
                     AVTPPTDQPAPAQ"
     gene            complement(4675..6324)
                     /locus_tag="MJ8_RS04440"
                     /old_locus_tag="MJ8_08840"
     CDS             complement(4675..6324)
                     /EC_number="6.1.1.6"
                     /GO_function="GO:0000049 - tRNA binding [Evidence IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872163.1"
                     /locus_tag="MJ8_RS04440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08840"
                     /product="lysine--tRNA ligase"
                     /protein_id="WP_201413268.1"
                     /transl_table=11
                     /translation="MTGSNIIDLNPEMLAAAAESKAWPFEEAKKIIARYKGKDFPETVL
                     FETGYGPSGLPHIGTFGEVARTTMVRHAFRVLTQDKVKTKLLCFSDDMDGMRKIPDNVP
                     DRAALEPYLHMPLTSVPNPFGGDYASFADHNNAMLCRFLDTFGFDYEFASATQYYKAGR
                     FDEVLLRAAERYDEIMGVMLPTLGPERQATYSPFLPISPRSGRVLYVPMINVDAKAGTI
                     TFDDEGTETTLPVTGGHVKLQWKPDFGMRWAALGVDFEMFGKDHQTNAAIYDRICNILG
                     GRAPEHFVYELFLDEVGQKISKSKGNGLTIDEWLTYAPTESLGLYMYQRPRQAKKLYFD
                     VIPKAVDEYYAFLGAYPRQDWKERLGNPVWHMHDGNPPAIDLPVPFALLLNLVSASNAH
                     DKSVLWGFISRHAPGVTPETHPELDRLTGYAIRYFDDFVKPTKVFRAADEVERDALAKL
                     SEALGALPPGADGEAIQNAALNVARKIERYQDHSKQSPEGGPGVSVAFFQMIYQVLIGQ
                     ERGPRFGSFAALYGIAETRALIERALAGQLAA"
     gene            6545..6958
                     /locus_tag="MJ8_RS04445"
                     /old_locus_tag="MJ8_08850"
     CDS             6545..6958
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872162.1"
                     /locus_tag="MJ8_RS04445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08850"
                     /product="tellurite resistance TerB family protein"
                     /protein_id="WP_201413269.1"
                     /transl_table=11
                     /translation="MPLLSPHEAVIHLMVITSASDRDMTDVELARIGDVVRSWPVFVDF
                     NQDRLVQVAQACQKALHDKDGLEGVLARVAEALPERLRDTAYAAAFEVAAVDLEMRMEE
                     VRVLQLIRLKLDLDTLTVAAIARAAKARLRTLT"
     gene            complement(6965..7913)
                     /locus_tag="MJ8_RS04450"
     CDS             complement(join(6965..7576,7578..7913))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612137.1"
                     /locus_tag="MJ8_RS04450"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS630 family transposase"
                     /protein_id="WP_201410559.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MVRPLSDDLRERVVAAVLSGESRRSAAKRFGIANSTAVKLLQRHQ
                     ATGSVAPGKMGGHRKRVLEPHRAFIVERINQTSDLSLHRLKDELAARGVKVSHNAVWQF
                     LRREGLSFKKTLFALEQARADIARRRQRWRSWQAGLDPQCLVFIDETWIKTNMAPLRGW
                     GPKGKRLRGLAPHGHWRTLTFLGALRCDRLAAPCVFDGPINGQCFRAYVEQQLITVLKP
                     GDIVIMDNLGSHKSAAIRQMIKAAGARLWYLPPYSPDLNPIEQAFAKIKHWMRQAQKRT
                     VEDTWRHIGHLVEAIEAAECKNYFENAGYASVKT"
     misc_feature    complement(7949..7958)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     gene            complement(8071..8892)
                     /locus_tag="MJ8_RS04455"
                     /old_locus_tag="MJ8_08880"
     CDS             complement(8071..8892)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006199959.1"
                     /locus_tag="MJ8_RS04455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08880"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_201415297.1"
                     /transl_table=11
                     /translation="MSALGGMLPFSSATQAAEPQVPVLWDAKERLPKPDLSALPRLRFL
                     TTTDFPPFNFLDGSGRLSGFHIDLARAICAELGIVEKCQVQALPWNELENALQKGEGEA
                     IIAGIAATSESREKYAFSRSYMQFPARFIMPKAKAIAEPILDKLRSKRVGVIGGSAHEK
                     MLRDYFNTVQVVTFDTPENLYADLKAGKIDAAFGDGMRFAFWLGGSDAAGCCRFAGGPY
                     LAPEYLGSGMAIATRKGDTALAAAFDYALQEISIKGTFAEFYLRYFPVSFF"
     misc_feature    complement(8854..8870)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.89"
                     /tool="antismash"
     misc_feature    complement(8956..8969)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.09"
                     /tool="antismash"
     gene            9171..9902
                     /locus_tag="MJ8_RS04460"
                     /old_locus_tag="MJ8_08890"
     CDS             9171..9902
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019863131.1"
                     /locus_tag="MJ8_RS04460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08890"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_201413270.1"
                     /transl_table=11
                     /translation="MGLFDRTLEYIDQLQHAGTAAAVCERLLGVTSNFGLTALMAGTVP
                     QPGTPRGQQKQHVLLCDWPGNWLERYVARNYVDHDPVVSHMKQLRAPFQWRDASKSAVI
                     DKSSDEVMGDAREFKLRDGLALPLVTLDGQIVMVSLGGESVELSDQEFGMVSLASTYAI
                     GRAMQLHTKADSVIDHIELTARERECLQWAAVGKSEWEISQILGISEHTSEKHLLNAKS
                     KLGAANRVQAVAEAIRRGYIS"
     gene            10001..10639
                     /locus_tag="MJ8_RS04465"
                     /old_locus_tag="MJ8_08900"
     CDS             10001..10639
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010913386.1"
                     /locus_tag="MJ8_RS04465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08900"
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_073989358.1"
                     /sec_met_domain="Autoind_synth (E-value: 4.1e-14, bitscore:
                     51.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFALTTQELMERPDLWEAVHRLRYKIFVEEMGWTDLDRPDQLEI
                     DQFDHDEAEHHLVIRNGELAGYQRMLPTTRPHLLTDVLSDLCEGPSPSGPNVWELTRYA
                     VAPGFRDGKRGVSTVGTELIAGFVEWGLKRNVNQVIIEFEPMWVLRALQLHFLAKPLGY
                     QRTYGNQQVVATLLTFTEHTLEVVRARRNHFLPVLNRGYPGQLGLKQAS"
     gene            10651..11400
                     /locus_tag="MJ8_RS04470"
                     /old_locus_tag="MJ8_08910"
     CDS             10651..11400
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (26-245). E-value: 1.2e-39. Score:
                     128.0. Matches aSDomain: nrpspksdomains_MJ8_RS04470_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006199955.1"
                     /locus_tag="MJ8_RS04470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08910"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_225248122.1"
                     /transl_table=11
                     /translation="MSFHPEPELRGHTLVVTVSSHDGRPVLDRHAYASLARTLHEAAVN
                     DEVRVVMLRGLAGCFCLGGDFSEFLDATKHRELIAAVTDMFRMLATFPKPVLACVDGDA
                     VGVGCTILFHCDMVIASKGSTFRVPFVDFGLVPDAATSILAPQKLGYAGAFRFFCLGDT
                     LGAEDAKALGLVGEVVTQGSAEEATLARAKQLAKKPVAALLQTRSLLKGDTDVLCDRID
                     HEITLFQQALQDDTTLKRLQRIARLAA"
     aSDomain        10729..11385
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MJ8_RS04470_ECH.1"
                     /evalue="1.20E-39"
                     /label="MJ8_RS04470_ECH.1"
                     /locus_tag="MJ8_RS04470"
                     /protein_end="245"
                     /protein_start="26"
                     /score="128.0"
                     /tool="antismash"
                     /translation="LDRHAYASLARTLHEAAVNDEVRVVMLRGLAGCFCLGGDFSEFLD
                     ATKHRELIAAVTDMFRMLATFPKPVLACVDGDAVGVGCTILFHCDMVIASKGSTFRVPF
                     VDFGLVPDAATSILAPQKLGYAGAFRFFCLGDTLGAEDAKALGLVGEVVTQGSAEEATL
                     ARAKQLAKKPVAALLQTRSLLKGDTDVLCDRIDHEITLFQQALQDDTTLKRLQRIA"
     gene            complement(11469..12374)
                     /gene="ppk2"
                     /locus_tag="MJ8_RS04475"
                     /old_locus_tag="MJ8_08920"
     CDS             complement(11469..12374)
                     /EC_number="2.7.4.1"
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006793 - phosphorus metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ppk2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872157.1"
                     /locus_tag="MJ8_RS04475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08920"
                     /product="polyphosphate kinase 2"
                     /protein_id="WP_201413271.1"
                     /transl_table=11
                     /translation="MKKAKETAEAVPDTAPIKIKIGGKEREFDIDNPVLPDWIEDNKLS
                     AGGYPYDKKMKGGDYEKELEGLQIELVKAQAWLQATGKRVMALFEGRDAAGKGGTIFVL
                     RQYMNPRTARNVALPKPTPTEAGQWYFQRYVDHFPTSGEFVTFDRSWYNRAGVEPVMGF
                     CTPEQHEKFLDETPHFERMISNEGIHFFKFWLNIGRETQLERFHDRRWSPLKNWKFSPI
                     DIAGVSKWDDYTKARDQMIERTHKEFAPWIVVRANDKRRARLAVIQRILLSLPYDGRNL
                     DAVGKPDKKIIGEGPEFLKD"
     gene            12574..13839
                     /locus_tag="MJ8_RS04480"
                     /old_locus_tag="MJ8_08930"
     CDS             12574..13839
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006199953.1"
                     /locus_tag="MJ8_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08930"
                     /product="ATP-binding protein"
                     /protein_id="WP_201413272.1"
                     /transl_table=11
                     /translation="MAETGAEQDGKGQALAARLRRNRWLLGVGVLAILAVYFFAGASVY
                     VPVLALVVLTAAAMLPTDAGRQPADTGAAIEASGLQRLSGEYLAAAVADPLIIFDHSAT
                     IVHANAAAFAAFGGLAPGMSLSLKFRAPEMQALLDGILSGQVAADAVDYTEKLPVERTY
                     RVSASTVGHATGLYVLVFKDQSETRRIDRMRADFIANASHELRTPLASIAGFIETLRGP
                     ARNDPAARDQFLQIMQNQTGRMARLIDDLLSLSRLEMKPYLKPGTEVDLRQTIDSVIDS
                     LGPLASENGVVIEREFANGQLVVPGDRDELFQVFENLLENACKYGQSGGRVTVSIAGSE
                     DGQQPGFDVTIRDYGPGIAEEHIPRITERFYRVDVESSRTQKGTGLGLSIVKHILTRHN
                     ARLSIKSEVGKGAAFTVHLPAR"
     misc_feature    13939..13952
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.06"
                     /tool="antismash"
     gene            13948..14670
                     /gene="phoU"
                     /locus_tag="MJ8_RS04485"
                     /old_locus_tag="MJ8_08940"
     CDS             13948..14670
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="phoU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015319295.1"
                     /locus_tag="MJ8_RS04485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08940"
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="WP_201413273.1"
                     /transl_table=11
                     /translation="MQSVHIMSAYDEELKFLSKRIAAMGGHAERMVEQAVAALVNVDHG
                     LAQKVIQDDLVLDEGQREIDDKAIIIIAKRQPMATDLREIVGAIRISADIERVGDLGKN
                     VAKRVASVDGRQPNSLFRGIEALANLALTQLKEVLDVYASRSVERIGFVRDRDDQIDAM
                     YTSLFRELLTYMMEDPRNITPCTHLLFCAKNIERIGDHATNIAETIYYIVTGDQMPTDR
                     PKGDKTDKVVLPGTVPAK"
     gene            14757..15761
                     /locus_tag="MJ8_RS04490"
                     /old_locus_tag="MJ8_08950"
     CDS             14757..15761
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006336017.1"
                     /locus_tag="MJ8_RS04490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08950"
                     /product="magnesium and cobalt transport protein CorA"
                     /protein_id="WP_201413274.1"
                     /transl_table=11
                     /translation="MEQVRNLTPAPTSGIIASSVYSGGKRVADIAIEQAGEWAAKPGHV
                     VWIGLLEPDRNLLLRVQAQFHLHDLAIEDAEHPHQRPKIEQYGDALFIVARTAQLIDGR
                     VTFGETHLFVGTGYIVSVRHGPSTSYAAVRQHWESCPHSLAKGEDFVLYAILDFIVDNY
                     MPVLEQIEDEVEAIEDKVLLKPMTGADIERLYMLRRDLLRLRNAALPLVEVCRRLTSAD
                     LLQIHAAMHPLFRDVTDHIRTVQEKIDSLREVLAFAFEASLLVGQSQETAISKKLASWA
                     AILAVPTAFAGIYGMNFTDMPELKMEYGYPTVLAVIALICAFLYWRFKKNGWL"
     gene            complement(15889..16407)
                     /locus_tag="MJ8_RS04495"
                     /old_locus_tag="MJ8_08960"
     CDS             complement(15889..16407)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008872153.1"
                     /locus_tag="MJ8_RS04495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08960"
                     /product="GcrA family cell cycle regulator"
                     /protein_id="WP_040985866.1"
                     /transl_table=11
                     /translation="MNWTDERVELLRKLWSEGLSASQIAAQLGGVSRNAVIGKVHRLKL
                     SGRGRATAAPARQKKATQGASMQKSVTRAASATRHVTATIGATALQVQFDAEPVARHYI
                     RPVENVVVPISRNLQLVELTERTCKWPNGDPLSEDFSFCGNDAAETGPYCKYHSRVAFQ
                     PAAERRRAR"
     misc_feature    complement(16367..16381)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.21"
                     /tool="antismash"
     gene            16764..17963
                     /locus_tag="MJ8_RS04500"
                     /old_locus_tag="MJ8_08970"
     CDS             16764..17963
                     /NRPS_PKS="Domain: Aminotran_3 (18-336). E-value: 7.6e-108.
                     Score: 352.4. Matches aSDomain:
                     nrpspksdomains_MJ8_RS04500_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019863139.1"
                     /locus_tag="MJ8_RS04500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08970"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_201413275.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-115, bitscore:
                     384.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGSALYETFARAPLAFDHGEGTWLVTDKGERYLDFAGGIAVNSL
                     GHSHPHLVAALTEQAAKLWHVSNLYEIPEQRRLGERLVEATFADKVFFTNSGAEALECA
                     IKTARRYQFVKGHPERFRIITFEGAFHGRTLATIAAGGQYKYLEGFGPKVEGFDQVAFD
                     DIDGAEKAITPETAAILIEPVQGEGGIRPVSTQSLKRLRQLCDQHGLLLIFDEVQCGIG
                     RTGKLFAHEWAGVTPDLMAIAKGIGGGFPMGACLATDEAATGMTAGVHGTTFGGNPLAM
                     AVGNAVLDVVLADGFLEDVQRKALLLKQGLAGVADEFPDVIEGIRGTGLMLGLKCAMPN
                     TKVNMALRDQHLLAVPAGDNVIRLLPPLTVTDEEIGEALERIRGGARVLTDAIAAEAAK
                     "
     aSDomain        16818..17771
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MJ8_RS04500_Aminotran_3.1"
                     /evalue="7.60E-108"
                     /label="MJ8_RS04500_Aminotran_3.1"
                     /locus_tag="MJ8_RS04500"
                     /protein_end="336"
                     /protein_start="18"
                     /score="352.4"
                     /tool="antismash"
                     /translation="HGEGTWLVTDKGERYLDFAGGIAVNSLGHSHPHLVAALTEQAAKL
                     WHVSNLYEIPEQRRLGERLVEATFADKVFFTNSGAEALECAIKTARRYQFVKGHPERFR
                     IITFEGAFHGRTLATIAAGGQYKYLEGFGPKVEGFDQVAFDDIDGAEKAITPETAAILI
                     EPVQGEGGIRPVSTQSLKRLRQLCDQHGLLLIFDEVQCGIGRTGKLFAHEWAGVTPDLM
                     AIAKGIGGGFPMGACLATDEAATGMTAGVHGTTFGGNPLAMAVGNAVLDVVLADGFLED
                     VQRKALLLKQGLAGVADEFPDVIEGIRGTGLMLGLKC"
     gene            17980..18891
                     /gene="argF"
                     /locus_tag="MJ8_RS04505"
                     /old_locus_tag="MJ8_08980"
     CDS             17980..18891
                     /EC_number="2.1.3.3"
                     /GO_function="GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="argF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019863140.1"
                     /locus_tag="MJ8_RS04505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08980"
                     /product="ornithine carbamoyltransferase"
                     /protein_id="WP_201413276.1"
                     /transl_table=11
                     /translation="MSVRHFTDLSAVSAGDLRSMLDDAVARKTRLKAGERSKPLDGKVL
                     AMIFDKPSTRTRVSFDVGMRQLGGETIMLTGTEMQLGRSETIADTAKVLSRYVDAIMIR
                     TTSHDRLIELTENATVPVINGLTDDTHPCQLMADIMTYEEHRGPVAGKTFAWTGDGNNV
                     LHSLLEASARFRFNLNVAVPEGSEPFEKYVDWSKANGGKVRFAKSAEEAVDQADCVVTD
                     SWVSMGQEHRARGHNVFLPYQVNAALMARAKPDALFMHCLPAHRGEEVTDEVIDGPHSV
                     VFDEAENRLHAQKAVLAWCLGA"
     gene            19015..20046
                     /locus_tag="MJ8_RS04510"
                     /old_locus_tag="MJ8_08990"
     CDS             19015..20046
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013533641.1"
                     /locus_tag="MJ8_RS04510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_08990"
                     /product="Hsp33 family molecular chaperone"
                     /protein_id="WP_201413277.1"
                     /transl_table=11
                     /translation="MAAPRSFVMLETHTLAEHKPQLGEFGFAGDDHVVPYEVAPLDVRG
                     RTVQLGPMLDAILSRHNYPEPVARLLAEACVLTVLLGTSLKFEGKFILQTRTDGPVDML
                     VADFTTPHALRAYARFDADRLRALNDAGETSQQALLGNGVLALTIDQGAHMQRYQGIVQ
                     LDGTSLEDAARTYFRQSEQIPTEIKMSVAKLVTPGPAGAREQWRAGGILAQFLPQAPER
                     MRIPDISGGDGDDREVTDHPADNSWQELLALLGTIEPTELIDPTVGAERLLYRLFHEHG
                     VRVFSGVPVADQCSCSRDKIRGILEGFSAQEIRDSTEDGGIHVACEFCSTQYDFDPAEF
                     GAE"
     gene            complement(20221..20613)
                     /gene="apaG"
                     /locus_tag="MJ8_RS04515"
                     /old_locus_tag="MJ8_09000"
     CDS             complement(20221..20613)
                     /codon_start=1
                     /gene="apaG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003530166.1"
                     /locus_tag="MJ8_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ8_09000"
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="WP_201413278.1"
                     /transl_table=11
                     /translation="MYRAVTRNIEVVVRPFYLEDRSDPSENRYVWGYQVTIDNRSDEFV
                     QLLSRYWHITDGQGRVEEVRGAGVVGDQPELNPGDSYQYTSGCPLSTPSGIMVGHYTMR
                     NGRGETFDIAIPAFSLDMPGTKRTVN"
ORIGIN
        1 ggacgagctg gagcgccgcg atttgaacac cgcgctggtc acgctctgca tcggcgccgg
       61 catgggcacc gccaccatca tcgaacgcgt ctgagggaga gagactatga gctacaccaa
      121 tttcaccctc gacgtggacg ccgacggtat cacgctggtc acctgggaca tgccggaccg
      181 ctcgatgaac gtcttcaccg aggaggtgat gcgcgagctg aacgccatcg tcgagaaggt
      241 gacagccgat gccgccgtca agggcgtcgt catcacctcg ggcaaggact ctttctccgg
      301 cggcgccgac atcaccatgc tgcagaagat gctggccacc ttcgccgtcg acaaggagaa
      361 ggacctcgag aaggcgacca aggcgctgtt cgagaatgcc ggctacatga ccggcctgtt
      421 ccgcaagatc gagacttccg gcaagccctg ggtgtcggcg atcaacggca cctgcatggg
      481 gggcgccttc gagatgtcgc tcgcctgcca tggccgcgtc gccgctgatt ccgataaggt
      541 gaagatggcg ctgcccgagg tgaagatcgg tatcttcccg ggcgctggcg gcacccagcg
      601 cgtgccgcgg ctgaccgacc agcagcaggc actgcaaatg ctgacctccg gccagaacct
      661 gacgccgcaa aaggcgaagg cgatgggtct gatccatgag atcgcggagc cgaagaagct
      721 gatcgaaacc gccaaggcga tgatcaggaa cggcctgaag ccggtggcgc cttgggacga
      781 gaagggcttc aagctgccgg gcggtccggt ctactcggcg gccggcgcca atctctggcc
      841 gccggccatc gccatcctgc gccgcgagac ctacggcaac tacccggccg cggccgcgat
      901 cctgaaatgc gtctatgaag gcctgctggt gccgttcgat accgcgctca ggatcgagca
      961 gcgttatttc accgagatca tgcagtcgaa ggaagcggcg gcgatgatcc gctcgctgtt
     1021 cctgtcgctg caggaactga acaagggcgc gcgccgcccg tccggcctgc cggacaccaa
     1081 attcaagaag atcggcattc tcggcgccgg cttcatgggc gccggcatcg cttatgttac
     1141 ggcaaaagcc ggcattccgg tcgtgctgct agaccgcgat ctgccgtcgg ccgagaaggg
     1201 caaggcgcat tccgacagcc tcatggccga tcagatcaag aagggtcgcg ccaagccgga
     1261 ggacaaggac aagctcctgt cgctgataac gccgacggcg gactatgccg atcttgccgg
     1321 ctgcgacctc gtcgtcgagg cggtcttcga ggattcgagc gtcaagaagg acgccaccga
     1381 gaaggcggaa gcggtgttga agtcgtcggc gatcttcgct tccaacactt cgacgatccc
     1441 gatcaccgct ttggcgaaga attcggcgcg gccgaagaac ttcatcggca tccacttctt
     1501 ctcaccggtc gacaagatga tgctggtcga gatcatcctc ggcaagaaga ccggcgacaa
     1561 ggccttggcc gtcgccttcg acttcgtacg cgccatcaag aagacgccca tcgtcgtcaa
     1621 cgacacgcgt ggcttctacg tcaaccgttg cgtgctgcgc tacatgtcgg aagcttacaa
     1681 gatgctgatc gaaggcgtgc cggcgccgat gatcgagaac gccgccaagg ccgccggcat
     1741 gccggtcggt ccgctcgcgc tgaccgacga gacggccgtc gaccttgccc agaagatcat
     1801 gaagcagacc atccgggatc tcggcgagaa ggccgtcgac cccaggcaga tggcgctgat
     1861 caacacgatg gtcgacacgc atggccgctt cggccgcaag aacggcaagg gtttctacga
     1921 ctatccggca aagcccgcga agaagaagct gtggccgggc ctgagggacc tctacccaca
     1981 gctgaagccc gaaaaggtcg actatgagga gctgaagcag cgcctcttgg tcaccatcgc
     2041 gctggaagcg gcgcgggtga tggaggaagg catcgtcacc gatccgcgcg aggcggatgt
     2101 cggctcgatc ctcgccttcg gcttcgcgcc cttcaccggc ggtgcgctgt cctacatcga
     2161 cggcatcggc gccaagcgtt tcgtcaagat cgccaagggt ctgcagaaga agtatggcgc
     2221 cgagttcaag gcgccgaagc ttctgctcga catggccgag aagggcgaga ccttctacca
     2281 gcgcttcgac ccctaccgga aaggcgaggt tcgagaggcg gcctgacgaa ccggaatgta
     2341 tgtctggggg cgaatggccc gcaccatggc cacggcatcg agccgtggcc cctatagggt
     2401 cggcgaggaa agccgactgg cttttcgctg cctgccgatc gacatcgatt tcaacctgca
     2461 cctgaacaac gcccgctaca tgatgctggc cgaccttggc cgtatcgaca tcttcctgcg
     2521 catcggcctt atcgcgctgg cgcgcaagaa tggctgggcg ccgatgatcg gcgggctgca
     2581 ggtcgcctat gtgcgtgaga tcaggctgtg gcggcgcttc gaggtggtct cgtcgatcga
     2641 gacctgggaa ggcacgtccg tcatcggcag gcaccgcttc gtcctcgacg gcggcgagac
     2701 cgcggcgctg atcctgacca cgggcggtgt ctatgaccgt gccggccgcc gcttcctcga
     2761 catcgaggag gtcgtcgcag cgctcggccg cgccgccggt ccacgcccgc cgaccgaggc
     2821 cgagcggacc ttcatggtgt cgcaccggaa tttgcgcgaa caggccaagg cggcctgatc
     2881 gcgcttcggc tcaggctgcc ctgccgagca ggaaatctgt cacctcgtcc gagaagacca
     2941 tcagctcatt gtcggaggcg acgacggttc gcctgccttg cggatacggt cgcccggcct
     3001 gcattccatg cgccacaagc gcctgccgaa ggccttggcc gggataggat aggaggtgcg
     3061 ctaggaggag gctcatggag tattgttaac gatccgccgg cagcaccggt ggacaagggc
     3121 atgactgcgc gctagacagg cttgaggcat tttttcctgt ttgaaggagt gcgcgcgtgc
     3181 tctcacacga ccgcgtatgg gccgcaatcg atgctctcgc tgagcgctat tcgctatcgg
     3241 cttccggact tgcccggcgc gcgggccttg actcgacagc cttcaacaag tcgaagcggc
     3301 tgtcgtccga cggccggccg cgctggccct cgaccgaatc gctggccaag atcatcgagg
     3361 ccaccggcgc ttcgctggag gaattcaccg gactggtcga aggtcgcagt ggcgcctccg
     3421 tcgcccagca ccgcagcgcg gttccattgc ttggcttcgc ccaggcggga gcggggggct
     3481 tcttcgacga tgcaggctat ccggccgggc agggctggga cctggtcgag cttccggcgc
     3541 gggcgaccga gacgtcctac gcgctgcagg tgcaaggcga ttccatgctg ccgctctacc
     3601 gcaacggcga tgtgctgatc gtcgagccgg gcgcgccgac ccgcaaaggc gatcgcgttg
     3661 tcgtcaagac caccgccggc gaggtgatgg ccaaggtgct cgaccggcaa acgatgaaat
     3721 cgatcgtgct ggtttcgctc aacccggacc accccgaccg ggacatcccg acgcgcgata
     3781 tcgaatggat ggcgcgcatc gtctgggcga gccagtaggc cgggctgatg cggcttcttc
     3841 agacagcctt ggcggtgctg gcggtcccgg tcatggcggc tcttgttgtt gccggcggac
     3901 acgcggtcaa gggccacgaa agcgccgtca cggtcgatca gatcgacccc atcgccgacg
     3961 cactccccac cggcgacaat acgctttccg cttccgatgc ggcgcaagag ccggcgacct
     4021 cggctattcc cgcgccggcc gctccacaac cgccgaagcc tgctgctcat tcgagggcca
     4081 tcgatcccga cgtcgtggcg ccacctgatc tttcagacaa cgaactggaa cgggtggagc
     4141 cgcgcgcgcc gctcagcgat ctggccctgg ccgggccgcc caagccgccc aagacgaaga
     4201 tgccaagcga ctggaacggc accaagctgt tccagccggt cgccaccgcc gccgggttga
     4261 tcgagtcgaa aggttatgcg gtcgccgtgt ccggcgtgga tgtcgtcaag gccgatgaga
     4321 cctgcagcga cgagggcaag agttgggcct gcggcgcccg cgccaggacg gccttccgcg
     4381 ccttcctgcg cggccgcgcg gtcgcctgca cggtgccgcc ggagggcggg cgcgacacca
     4441 tcaccgccga atgccatatc ggcaatcagg acatcggcca gtggctggtc gagaacggct
     4501 gggcgcgcgc cgcgcaaggc gggccctatg tcgaggccga gaacaaggcc cgcacggcaa
     4561 ggaagggtat tttcggcccg gcgccgaagc tcgacgggct gccggcggtg ccggccgcgt
     4621 cgggtccggc gccggtggcg ccggattcga tcctgccggc cgatggcggg gccgttacgc
     4681 cgccaactga ccagccagcg cccgctcaat gagcgcgcgt gtctcggcga tgccgtaaag
     4741 cgccgcgaag gaaccgaagc gcggtccgcg ctcctggccg atcagcacct ggtagatcat
     4801 ctggaagaag gcgaccgaca cgccgggccc gccttccggg ctctgcttgg aatggtcctg
     4861 gtagcgctcg atcttgcgcg ccacattgag cgcggcgttc tggatcgctt cgccgtcggc
     4921 gcccggcggc agcgcgccga gtgcctcgga gagcttggcc agcgcgtcgc gctccacctc
     4981 gtcggccgcg cgaaaaacct tggtcggctt cacgaagtcg tcgaaatagc ggatcgcgta
     5041 gccggtcagc cggtcgagtt cgggatgcgt ctccggcgtc acgcccggcg catgccgcga
     5101 gatgaagccc cacagcaccg acttgtcatg cgcgttggag gcgctgacca ggttgagcag
     5161 cagcgcgaaa ggcaccggca ggtcgatcgc cggcgggttg ccgtcatgca tgtgccagac
     5221 cggattgcca agccgttcct tccagtcctg gcgcggatag gcgccgagga aagcgtaata
     5281 ctcatccacc gccttcggga tgacgtcgaa atagagcttc ttcgcctgcc gcggccgctg
     5341 gtacatgtaa aggccgaggc tttcagtcgg cgcgtaggtc agccattcgt cgatggtgag
     5401 cccattgccc ttcgacttgg agattttctg gcccacctcg tcgaggaaca gctcgtagac
     5461 gaaatgctcc ggcgcgcgac cgccgaggat gttgcagatg cggtcgtaga tcgccgcatt
     5521 ggtctggtgg tccttgccga acatctcgaa atcgacgccc agcgccgccc agcgcatgcc
     5581 gaaatccggc ttccactgca gcttcacatg gccgccggtg accggcagcg tcgtctcggt
     5641 gccttcgtcg tcgaaggtga tggtgccggc cttggcgtcg acattgatca tcggcacgta
     5701 gagcacgcgg ccgctcctcg gcgagatcgg caggaacggg ctgtaggtcg cctggcgctc
     5761 cggcccgagc gtcggcagca tcacgcccat gatctcgtca tagcgttcgg cggcgcgcag
     5821 cagcacctcg tcgaaacggc cggccttgta gtactgcgtc gcgctggcga actcgtagtc
     5881 gaagccgaat gtgtcgagga agcggcacag catcgcattg ttgtggtcgg cgaagctcgc
     5941 atagtcgccg ccgaacggat tgggcaccga ggtcagcggc atatgcagat agggctcgag
     6001 cgcggcgcgg tccggcacgt tgtccggtat cttgcgcatg ccgtccatgt cgtcggagaa
     6061 gcacaggagc ttggtcttga ccttgtcttg cgtcagcacc cggaaggcat gccgcaccat
     6121 ggtcgtgcgc gccacttcgc cgaaggtgcc gatatgcggc aggccggacg ggccgtagcc
     6181 ggtctcgaac aggacggttt cggggaaatc cttgcctttg tagcgggcga tgattttctt
     6241 ggcttcctcg aacggccagg ccttgctctc ggctgccgcg gcaagcatct cgggattgag
     6301 atcgatgatg tttgatcccg tcatatcgaa gttccaatca tggccgtctg cgcggcggat
     6361 aagagcggat aagatttgtc gacggtctct aggcgcgcga gaccggagcg tcaacgattt
     6421 gcgccggttt tccttgcggc gccataatgg cgctcctacg ttggagcctc agtttcaagt
     6481 gcatgtcacc caaaggcatg ttgcggcttt ggggcaacaa catgcacgcc attaggagtt
     6541 ttgaatgcct ttgctgagcc cgcatgaagc cgtgatccac ttgatggtca tcacatcggc
     6601 ttcggatcgc gacatgaccg atgtcgagct cgcgcggatc ggcgatgtcg tccgctcctg
     6661 gccggtgttc gtcgatttca accaggacag gctggttcag gtggcacaag cctgtcagaa
     6721 ggcgctgcac gacaaggacg ggctggaagg cgtgctggcg cgtgtcgccg aagcgctgcc
     6781 cgagcggctg cgcgacaccg cctacgccgc cgccttcgag gtcgccgccg tcgatctcga
     6841 gatgcgcatg gaggaggtca gggtgctgca gctcatccgc ctcaagctcg atctcgacac
     6901 actgaccgtg gccgcgatcg cgcgtgcagc caaagcgcgc ctgcgcacgc tgacttagag
     6961 tctttcatgt tttgacggaa gcgtatccgg cgttttcgaa gtagttcttg cattcggctg
     7021 cctcgatggc ttcgacgagg tggccgatgt gtcgccaagt gtcctcgacg gtgcgtttct
     7081 gcgcctggcg catccagtgc ttgatcttgg cgaaggcctg ctcgatcgga ttgaggtccg
     7141 gtgagtaggg cggcaggtac cagagcctgg cgccagcggc tttgatcatc tgcctgatgg
     7201 ccgccgactt atggctgccc aggttgtcca tgatgacgat gtcgccgggc ttcagcacgg
     7261 tgatgagctg ctgctcgaca taggcgcgga agcattgacc gttgatcggt ccgtcgaaga
     7321 cgcaaggtgc cgcgagccga tcacagcgca gcgcgccgag gaaagtcagc gtgcgccaat
     7381 gaccatgtgg agccaggccg cgcagccgct tgcccttcgg cccccagccg cgcaggggag
     7441 ccatgttggt cttgatccag gtctcatcga tgaagaccag gcattgggga tcgaggccgg
     7501 cctgccagga tcgccatcgc tggcgccgac gggcaatatc ggcacgtgcc tgctcaaggg
     7561 cgaacagcgt tttttttgaa gcttagccct tcgcggcgca ggaactgcca caccgcattg
     7621 tgcgagacct tgaccccgcg cgcggccaac tcgtccttca gccgatgtag cgacagatca
     7681 gaggtctggt tgatccgctc cacgatgaag gctcgatgcg gttccagaac ccgcttacgg
     7741 tggccaccca tcttgcccgg cgccaccgag ccggttgcct gatgacgctg caacaatttc
     7801 acggctgtcg aatttgcgat accgaaccgc ttggcggccg accggcggct ctcgccactc
     7861 aaaaccgccg caacaacccg ctcgcgtaaa tcatcggaaa gaggtcgaac catcagatgc
     7921 tggcctccta tccagccagc atcttgaatc acaaatcagg ccgagcggga atcccctccg
     7981 attcaatcaa gctatgaaac gctctagcgt tggcgggacg cggttgctga aatccaggtc
     8041 aggccggcat cacctgaata tcagcaacct tcagaagaag ctgacaggaa aatagcgcag
     8101 gtagaactct gcgaacgtgc ctttgatcga gatttcctgc agcgcgtagt cgaaggcggc
     8161 ggcaagcgcg gtatcgccct tgcgggtggc gatcgccatg cccgagccca gatattccgg
     8221 cgccagatat gggccgccgg cgaatcggca gcagccggcg gcgtcggagc cgcccagcca
     8281 gaaggcaaag cgcatgccgt cgccgaaggc ggcgtctatc ttgccggcct tgaggtcggc
     8341 gtagaggttt tccggtgtgt cgaaggtcac cacctgcacg gtgttgaagt aatcgcgcag
     8401 catcttctca tgcgccgagc cgccgatgac gccaacccgc ttgctgcgca gcttgtcgag
     8461 gatcggctcg gcgatggcct tcgccttcgg catgatgaag cgggccggga attgcatgta
     8521 ggagcgcgag aaggcgtatt tctcgcggct ttctgacgtt gcggcgatgc cggcgatgat
     8581 agcctcgcct tcgcctttct ggagagcatt ctccaattcg ttccagggca acgcctggac
     8641 ttggcatttc tcgacaatgc ccagctccgc gcaaatcgcc cgcgccagat cgatgtggaa
     8701 gcccgacaac cggcctgagc cgtcgaggaa gttgaagggc ggaaaatcgg tggtggtgag
     8761 gaatctgagt cgcggcagcg ccgagagatc gggtttcggc agccgctcct tggcgtccca
     8821 cagcaccggc acctgcggct ccgccgcctg agtcgcactg gaaaagggca gcatcccgcc
     8881 cagcgccgac atcagggcaa gaaatgtcca ccgcaagatc acgatatggc tccgcgcctg
     8941 tccccgttcc ttggcttttc gtatgaaaac ggggcaggca caacggtttt tgatttcaag
     9001 cggccaaatt aagcgtatgc ttgggcgcgt ttgcaagtga ccttacgtgc cggaaggggg
     9061 aactgccggc tttgctgagg agatcgcgac gcgggggttg atggcgaagg ggtgttcggg
     9121 catctaccgt cggtaactaa aagcagaagc aacatggggt agatgttgcg atgggcctgt
     9181 tcgacagaac tctggaatac atagaccagt tgcagcatgc cggcaccgcg gccgcggttt
     9241 gcgagaggct gctcggcgtc acctcgaatt tcggcctgac cgctctgatg gcgggaacgg
     9301 tgccgcagcc cggcacgccg cgcggtcagc agaagcagca tgtgctgctt tgcgattggc
     9361 caggcaattg gctggaacgc tatgtggcgc gcaactatgt cgaccacgat ccggtcgtca
     9421 gtcacatgaa gcagcttcgg gcgccgttcc aatggcggga tgcttccaaa agcgccgtga
     9481 tcgacaaaag cagcgacgaa gtcatgggcg acgcgcgcga gttcaagctg cgcgatggct
     9541 tggcgcttcc gctggtcacg ctcgacggcc agatcgtcat ggtctcgctg ggcggcgaat
     9601 ccgtcgaact gtcggaccag gaattcggga tggtctcgct ggcatcgacc tacgcgatcg
     9661 gtcgcgcgat gcagttgcac accaaggccg acagcgtcat cgatcacata gaattgacgg
     9721 cgcgtgagcg ggaatgcctg caatgggccg ccgtcggcaa gtccgaatgg gagatctcgc
     9781 aaatcctcgg catctcggaa cacacttccg agaaacacct tcttaacgcc aagagcaaac
     9841 tgggcgcagc caaccgcgtg caggcagtcg cggaggcgat taggcgcggc tatattagct
     9901 aggtcggccg tgccgacctg gaaattcttg cctgcgcagt cgcgcaatat tttaagggac
     9961 atcacggccg tatcttcctc ttaagcctag gagacggcta atgcttttcg cccttaccac
    10021 tcaggaactg atggaacgtc ccgacctctg ggaggcggtt catcgcctgc gctacaagat
    10081 cttcgtcgag gagatgggat ggaccgatct cgatcgcccg gaccagctcg agatcgatca
    10141 gttcgatcat gacgaggccg aacatcacct cgttatccgc aacggtgaac tggcaggtta
    10201 ccagcgtatg ctgccgacca cgcggccgca tcttctgacg gatgtgctgt cggatctctg
    10261 cgagggaccg tccccctcgg gaccgaatgt ctgggaactt acccgctatg ccgtggctcc
    10321 gggttttcgc gacggcaaac gcggcgtctc gacggtcggg accgaactga tcgccggctt
    10381 cgtcgaatgg ggcctgaagc gcaacgtcaa ccaggtcatc atcgagttcg agccgatgtg
    10441 ggtgctcaga gcgctgcagc tgcatttcct ggcaaagccg ctcggctacc agcgcaccta
    10501 tggcaaccag caggtcgtgg cgacgctgct cacctttacc gagcatacgc tcgaggtcgt
    10561 tcgggcccgc cgcaatcact tcctgccggt gctgaaccgg ggctatcccg gccagctcgg
    10621 tctgaagcag gcgtcgtgat ggaggcggtc atgagtttcc atcccgaacc ggaactgcgt
    10681 ggccacacgc tggtcgtcac cgtgtcctcg cacgatggcc ggccagtgct cgacagacac
    10741 gcctatgcaa gcctcgccag gaccttgcac gaggcggcgg tcaatgacga ggtccgcgtc
    10801 gtcatgctgc gcggacttgc cggatgcttc tgccttggcg gcgacttctc ggagttcctc
    10861 gacgccacca agcaccgaga gctgatcgcc gccgtcaccg acatgttccg catgttggcg
    10921 accttcccca agccggtcct tgcctgtgtc gacggcgatg ccgtcggcgt cggctgcacc
    10981 atcctgttcc actgcgacat ggtgatcgct tccaagggca gcaccttcag ggtgccgttc
    11041 gtcgatttcg gcctcgtgcc ggacgcggcg accagcattc tggcgcccca gaagctcggc
    11101 tatgccggcg ccttccgctt cttctgcctc ggcgacacgc tgggcgccga agacgccaag
    11161 gcgctcggct tggtcggcga ggtcgtgacg caaggcagcg ccgaggaagc aacgctggcc
    11221 agggcgaaac agctggccaa gaagcctgtg gccgcattgc tgcagacgcg cagcctgctc
    11281 aagggggata cggacgtctt gtgcgaccgc atcgaccacg agatcacgct gttccagcag
    11341 gcgcttcagg acgacaccac gctgaagcgg ctgcagcgga tcgcccgcct ggccgcttga
    11401 gcgccggcat gaaagtctca gcgtcgcgcg aggcgaaagc cgcgcggcgc tgtaactcat
    11461 gcaattgatt agtctttcag gaactccggc ccttcgccga tgatcttctt gtcgggcttg
    11521 ccgacggcgt cgaggttcct tccgtcatag ggcagggaga gcaggatgcg ctggatcacc
    11581 gcgagccggg cgcggcgttt gtcgttggcc cgcacgacga tccagggcgc gaactccttg
    11641 tgcgttcgct cgatcatctg gtcgcgcgcc ttggtgtagt catcccattt gctgacgccg
    11701 gcaatgtcga tcggcgagaa cttccagttc ttcaacggcg accagcggcg gtcatggaac
    11761 cgttcgagct gtgtttcgcg gccgatattc agccaaaatt tgaagaaatg gatgccttcg
    11821 ttgctgatca tccgctcgaa atgcggtgtc tcgtcgagga atttctcgtg ctgctcgggc
    11881 gtgcagaacc ccatgaccgg ctcgacgccg gcgcggttgt accaggagcg gtcgaaggtg
    11941 acgaactcgc ccgaagtcgg gaaatgatcg acatagcgct ggaagtacca ttgcccggcc
    12001 tcggtcggcg tcggcttggg cagcgcgacg ttgcgtgccg tgcgcgggtt catatattgc
    12061 cgcagcacga agatcgtgcc gcccttgccg gcggcgtccc tgccctcgaa cagcgccatc
    12121 acccgcttgc cggtcgcctg cagccaggcc tgcgccttga ccagttcgat ctgcagccct
    12181 tcgagctcct tttcgtagtc cccgcctttc atcttcttgt cgtaaggata gccgccggcg
    12241 ctgagcttgt tgtcctcgat ccagtcaggc agcaccggat tgtcgatgtc gaactcgcgc
    12301 tccttgccgc cgatcttgat cttgatcggt gccgtgtctg gcaccgcttc agccgtttcc
    12361 ttggcctttt tcatccggac gaacctttcc agtttgcgga ctcatgctat ggagcctgtg
    12421 cagcgcagcg cgcattcggg cgcaaagacg ctgtagcatt ttgattttgc gcatgaacct
    12481 tcgcgaaaat cgatcctgat tttcacggcc atgcgccagg ctggtccagc gaaccgctga
    12541 ccggtcgacg ggatgcgggg gtggcgcggg cctatggcag agacaggcgc ggagcaggac
    12601 ggcaagggac aagccctggc ggcgcggctt cggcgcaacc gctggctgct tggcgtgggt
    12661 gttctcgcga tccttgccgt ttattttttc gccggcgcgt ccgtttacgt gccggtcctg
    12721 gccctggtgg tgctgacggc ggccgcaatg ctgcccacgg atgccgggcg ccagccagcc
    12781 gacacgggag cagcgatcga ggcaagcggg ctgcagaggc tctccgggga atatctggcg
    12841 gccgcggtcg ctgatccgct gatcatcttc gaccattccg ccaccatcgt tcacgccaac
    12901 gccgccgctt tcgccgcctt tggcgggctt gcgccgggca tgtcgctgtc gttgaagttc
    12961 cgcgctccgg aaatgcaggc gctgctggat ggcatcctgt cgggacaggt cgccgccgac
    13021 gcggtcgact acaccgaaaa gctgccggtg gagcgcactt accgtgtcag cgcgtccacg
    13081 gtcggccatg ccaccggcct gtacgtgctg gtcttcaagg atcagagcga gacgcgccgc
    13141 atcgatcgca tgcgggccga cttcatcgcc aatgccagcc atgagctgcg cacgccgctc
    13201 gcctcgattg ccggtttcat cgagacgctg cgcgggccgg cccgcaacga tccggcggcg
    13261 cgcgaccagt tcctgcagat catgcagaac cagaccgggc gcatggcccg cctgatcgac
    13321 gatctgctct cgctgtcgcg gctggagatg aaaccctatc tgaagccggg cacggaggtc
    13381 gatcttcgcc agacgatcga cagcgtcatc gattcgctag ggccgctggc cagcgagaac
    13441 ggcgtcgtca tcgagcggga gttcgccaat gggcagcttg tcgtgcccgg cgaccgcgac
    13501 gaactgttcc aggttttcga gaatctcctc gagaatgcct gcaaatacgg ccagtcgggc
    13561 gggcgggtca cagtgtcgat cgccggtagc gaggatggcc aacagccggg cttcgacgtc
    13621 acgataaggg attatggtcc gggtatcgcc gaagaacaca tcccgcgcat caccgagcgc
    13681 ttctaccgcg tcgatgtcga aagcagccgt acccagaaag gcaccgggct tggcctttcg
    13741 atcgtcaagc atatattgac tcgtcacaat gccaggctgt cgatcaagtc ggaagtcggc
    13801 aagggcgcgg cgtttacggt tcatttgccg gctcgctgat cctgtactgg ttaccaaccg
    13861 gcattttctt ctttctgtca tgcggttcgc gtatcagcga cggattgagg aaacgaacaa
    13921 accggcagaa gctgggaagg catgcccatg cagtccgtgc acatcatgag tgcctatgac
    13981 gaggaattga agttcctctc caagcgcatc gccgcgatgg gcgggcatgc ggagcgcatg
    14041 gtcgaacagg ccgttgccgc cctggtcaat gtcgaccatg gcctcgccca gaaggtcatc
    14101 caggacgatc tcgtcctcga cgaagggcag cgcgagatcg acgacaaggc catcatcatc
    14161 atcgccaagc gtcagccgat ggcgacggat ctgcgcgaga tcgtcggcgc catccgcatc
    14221 tcggccgaca tcgagcgggt cggcgatctc ggcaagaatg tcgccaagcg cgtcgcttcg
    14281 gtcgacggcc gtcagccgaa cagccttttc cgcgggatcg aggcgcttgc caacctggcg
    14341 ctgacgcaac tcaaggaagt gctcgacgtc tatgcctcgc gctcggtcga aaggatcggc
    14401 ttcgtgcgcg acagggacga ccagatcgac gccatgtaca cctcgctgtt ccgcgagctt
    14461 ttgacctaca tgatggaaga tccgcgcaac atcacgccct gcacgcatct tctgttctgc
    14521 gccaagaata tcgagcgcat cggcgaccat gccaccaaca tcgccgagac catctactac
    14581 atcgtcaccg gcgaccagat gcccaccgac cgccccaagg gcgacaagac cgacaaggtc
    14641 gtgcttcccg gcacggtgcc ggctaagtga acgggcgccc ctcgaacggt ttcctaattt
    14701 aggttaagct cctccaggga cagcgatttg tcggtcgcgg tctcgggagg tttgcgatgg
    14761 aacaagttcg gaacctgacc ccggccccaa cgtcgggcat cattgcatcc agcgtctatt
    14821 cgggaggaaa gcgggttgcc gacatcgcca tcgaacaggc cggcgaatgg gcggcgaaac
    14881 ccggccatgt cgtctggatc gggctgctcg agcccgatcg caaccttctg ctcagggtgc
    14941 aggcgcaatt ccatctgcat gatttggcga tcgaggatgc cgagcatccg catcagcgcc
    15001 cgaagatcga gcaatatggc gatgcgctct tcatcgtcgc ccgcaccgcg cagttgatcg
    15061 acggccgcgt cacgttcggc gagacgcatc tgttcgtggg caccggctat atcgtcagcg
    15121 tccggcacgg cccctcgaca tcatacgcgg ccgtgcgcca gcactgggaa agctgcccgc
    15181 attccctggc caagggcgag gacttcgttc tctacgccat cctcgatttc atcgtcgaca
    15241 attacatgcc ggtgctggag cagatcgagg acgaggtcga ggcgatcgag gacaaggtgc
    15301 ttttgaagcc gatgaccggc gccgacatcg aacgcctgta catgctgcgc cgcgatctgt
    15361 tgcggctgcg caacgcggcc ctgccgctgg tcgaggtctg ccgcagactg accagcgccg
    15421 atctgctgca gatccatgcc gccatgcatc cgctgtttcg cgacgtgacc gaccacatcc
    15481 gcaccgtgca ggaaaagatc gacagcctgc gcgaggttct ggccttcgct ttcgaagcga
    15541 gccttctcgt cggacagagt caggaaaccg ccatctccaa gaagctcgcc tcatgggctg
    15601 ccattctggc ggtgccgacg gccttcgccg gcatctacgg catgaacttc accgacatgc
    15661 cggaactgaa gatggaatac ggctatccga ccgtgcttgc ggtgatcgcg ctgatctgcg
    15721 cgttcctgta ctggcggttc aagaagaatg ggtggctgtg aagagacggg aataggggag
    15781 tagggcagta agggagtaag gttatacggg agtgatcgac tggcgaaaca tcgcgcatga
    15841 aacgcttctc ttcacctact cccctactgc cttactcccc tattcccctt atcttgccct
    15901 gcgccgctcc gccgccggct ggaacgcaac ccgcgaatga tacttgcagt acggccccgt
    15961 ttcggcggcg tcgttgccgc agaagctgaa gtcttccgag agcgggtcgc cgttcggcca
    16021 tttgcaggtg cgttcggtca gttcgacgag ctgcaggttg cgtgagatcg gcaccacgac
    16081 attctcgacc gggcggatat agtggcgcgc gaccggctcg gcgtcgaact gcacctgcag
    16141 cgcggtggcg ccgatggtgg ctgtcacatg gcgtgtggcg cttgcggctc gggtcaccga
    16201 tttctgcatc gatgcgcctt gcgtcgcctt cttctggcgc gccggggcgg ccgtcgcgcg
    16261 gccgcgaccc gacagcttca ggcgatgcac cttgccgata acggcgttgc ggctcactcc
    16321 gccaagctgt gcggcaatct ggctggcgct cagaccctcc gaccacaatt tcctgagaag
    16381 ttctacccgc tcgtcagtcc aattcatggg gtcgcgctcc tgctgaagcg tgcggtagtc
    16441 agaatccatt cccgacccgg ctctcgccgg gcgaacaaca ccacatatac cgggtgattt
    16501 aggtccgccg cacgaaatct agctatttct cgactacaaa taccttatgc gctgactcgg
    16561 tgacaagagt ccccagggca acacgattcg gttttttcgg ttttccccaa cttgccggtc
    16621 tactcatgag ccggcgtggc gtcagggctt tgtcacgcgc tctgcgtgac gttttcgttg
    16681 acttcatggc cgaaaaacat gataagccgc aaaggccgcc gcattggcgg cttttttgat
    16741 ttccggttcc ggagacgcat ataatgagcg gttcggcgct ttacgagacc tttgctcgcg
    16801 cacccctggc tttcgatcac ggggagggga cctggctggt caccgacaag ggcgagcgat
    16861 atctcgactt cgcgggcggc atcgcggtga attcgctggg ccacagccac ccgcatctcg
    16921 tcgcagcgct caccgagcag gccgccaagc tttggcatgt ctccaatctc tacgagatcc
    16981 cggaacagcg ccggctgggc gagcggctag tcgaggcgac cttcgccgac aaggtgttct
    17041 tcaccaattc cggcgccgag gcgctggaat gcgccatcaa gacggccagg cgctaccagt
    17101 tcgtcaaggg ccatcccgag cgtttccgca tcatcacttt cgagggcgcc ttccacggtc
    17161 gcactctggc gacgatagcc gccggcggac agtacaaata tctggaaggc ttcggcccga
    17221 aggtcgaggg cttcgaccaa gtcgctttcg acgacatcga cggcgctgaa aaagcgatca
    17281 cgccggagac ggcggcaatc ctgatcgagc cggtgcaggg cgagggcggc attcgcccgg
    17341 tgtcgacgca gtccttgaaa cggctgcgcc agctctgcga ccagcacggc ctgcttttga
    17401 tcttcgacga ggtccagtgc ggcatcggcc gcaccggcaa attgttcgcg catgagtggg
    17461 cgggcgtcac gcccgacctg atggcgatcg ccaagggcat cggcggtggc ttcccgatgg
    17521 gcgcctgcct tgccacggac gaggcggcga ccggcatgac ggccggcgtg cacggcacca
    17581 ccttcggcgg caatccgctg gcgatggcgg tcggcaacgc cgtgctcgac gtggtgctgg
    17641 ccgacggttt ccttgaggac gtgcagcgca aggcgctgct tctgaaacag gggctggccg
    17701 gggtcgcgga cgaatttccc gacgtcatcg agggcatcag gggaaccggc ctgatgctcg
    17761 gcctgaaatg cgccatgccc aacaccaagg tgaatatggc gctgcgcgat cagcacctgc
    17821 ttgccgtgcc ggcgggcgac aatgtcatcc gcctcctgcc gccgctcacc gttactgacg
    17881 aggagatcgg cgaagcgctg gagcgcattc gcggcggcgc cagagtcctg accgacgcga
    17941 ttgcggccga agccgcgaaa taatttctgg aacctgccga tgagtgttcg ccacttcacc
    18001 gatctatccg ccgtttccgc gggcgacctg cgctcgatgc tggacgacgc ggtggcgcga
    18061 aagaccaggc tcaaggcggg cgagcgctcc aaaccgctcg acggcaaggt gctggcgatg
    18121 atcttcgaca agccgtcgac gcgcacgcgc gtgtccttcg atgtcggtat gcgccagctt
    18181 ggcggcgaaa ccatcatgct gaccggcacc gagatgcagc tcggccggtc ggagaccatc
    18241 gccgacacgg cgaaagtgct gtcgcgctat gtcgacgcca tcatgatccg caccacctcg
    18301 catgaccggc tgatcgaact caccgagaac gccaccgttc cggtcatcaa cgggctgacc
    18361 gacgacacgc atccgtgcca gctcatggcc gacatcatga cctatgagga gcatcgcggt
    18421 ccggtggccg gcaagacctt cgcctggacc ggcgacggca acaatgtgct gcattcgctg
    18481 ctcgaagcct ctgcgcggtt ccgcttcaac ctcaatgtcg cggtgccgga gggcagcgag
    18541 ccattcgaga aatatgtcga ctggtcgaaa gccaatggcg gcaaggtccg gtttgccaag
    18601 tccgccgagg aagccgtcga ccaggctgat tgcgtcgtca ccgatagctg ggtctcgatg
    18661 ggccaggaac accgcgcccg cggtcacaac gtcttcctgc cctatcaggt caatgccgcg
    18721 ctgatggcaa gggccaagcc cgatgctttg ttcatgcact gcctgccggc gcatcgcggc
    18781 gaggaggtca ccgacgaggt gatcgacggg ccgcattcgg tggtcttcga cgaggccgag
    18841 aaccggctgc acgcccagaa ggcggtgctg gcctggtgcc tgggcgcttg agacggcgga
    18901 cctgatcgct tccggtcccg atcggcgtca acttgatctg ggggtatgtg atgcctattt
    18961 gcgggccatc acgtaaattg aacgcgcttc gacgcatgcg gctcttcggg cggcatggct
    19021 gcgccccgga gttttgtcat gttggaaacc cataccttgg ctgagcataa accccaactc
    19081 ggtgaattcg gcttcgccgg cgacgatcac gtcgttccgt atgaggtcgc gccgctcgat
    19141 gtgcgcggcc gcaccgtgca gctcgggccg atgctcgacg ctattctgag ccgccacaat
    19201 tatcccgagc ccgtcgcccg cctgctggcg gaggcctgcg tgctcaccgt gctgctcggc
    19261 acctcgctga aattcgaagg caagttcatc ttgcagaccc gcaccgacgg tccggtcgac
    19321 atgctggtgg ccgatttcac cacgccgcat gcgctgcgcg cctatgcgcg cttcgatgcc
    19381 gaccggctgc gggcgctgaa cgacgccggc gagacctcgc agcaggcgct gctcggcaac
    19441 ggcgtgctgg ctctgaccat cgaccagggc gcacatatgc agcgctacca gggcatcgtc
    19501 cagctcgacg gcacctcgct ggaggacgcc gcgcgcacct atttccgcca gtcggagcag
    19561 atcccgaccg agatcaagat gtcggtcgcc aagctggtca cgcccggccc ggccggcgcg
    19621 cgcgagcagt ggcgcgccgg cggcatcctg gcgcagttcc tgcctcaggc gcccgagcgc
    19681 atgcgcattc ccgatatttc gggcggcgac ggcgacgacc gcgaggtgac ggaccatccg
    19741 gccgacaatt cctggcagga attgctggcg ctgctgggca ccatcgagcc gaccgagctc
    19801 attgacccaa cagtgggcgc cgaacggctg ctctaccggc tgttccacga gcacggcgtg
    19861 cgcgttttca gcggcgtgcc ggtcgccgac caatgctcct gctcgcgcga taaaatccgc
    19921 ggcatcctgg aaggcttttc ggcgcaggag atcagggact cgaccgagga cggcggcatc
    19981 catgtcgcct gcgaattctg ctcgacgcaa tacgacttcg atccggccga gttcggggcg
    20041 gagtaacgct ccttccttct cccctccacg gggagaaggt gcccgaaggg cggatgaggg
    20101 gcggcgccaa cgtaggcgag gttggaaccc ttgccccgtc ctgacgaaat tctcggaagc
    20161 cggcgccgcc ctctcattgc cctgccgggc atttctcccc gtaaaacggg gagaaggagg
    20221 ttaattcacc gtccgcttcg tccccggcat gtcgagcgag aaagccggta tggcgatatc
    20281 gaacgtctcg ccgcggccgt tgcgcatggt gtagtggccg accatgatgc ccgacggcgt
    20341 cgagagcgga cagcctgatg tgtattgata gctgtcgccg ggattgagtt caggctgatc
    20401 gccgacgacg ccggcgccgc ggacctcctc gacccggccc tgcccgtcgg tgatgtgcca
    20461 atagcgcgac aaaagctgca cgaactcgtc ggagcggttg tcgatcgtca cctggtagcc
    20521 ccagacatac cggttctcgg acggatcgga gcgatcctcc agatagaagg gtctgaccac
    20581 cacttcgatg ttgcgcgtca ctgcgcgata catgggccac tccggttgcc gccgcggaa
//
