LOCUS       NZ_JADDUE010000013     22081 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Saccharopolyspora sp. HNM0986
            NODE_13_length_147214_cov_67.050689_cov_67.050689, whole genome
            shotgun sequence.
ACCESSION   NZ_JADDUE010000013
VERSION     NZ_JADDUE010000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Saccharopolyspora sp. HNM0986
  ORGANISM  Saccharopolyspora sp. HNM0986
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharopolyspora.
REFERENCE   1  (bases 1 to 147214)
  AUTHORS   Li,F.
  TITLE     Diversity and distribution of actinomycetes associated with coral in
            the coast of Hainan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 147214)
  AUTHORS   Li,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-OCT-2020) chool of Life and Pharmaceutical Sciences,
            Hainan University, 58 Renmin Avenue, Meilan District, Haikou, Hainan
            570208, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 232.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016526145.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 02:15:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,899
            CDSs (total)                      :: 5,838
            Genes (coding)                    :: 5,784
            CDSs (with protein)               :: 5,784
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 7 of 54
            Pseudo Genes (incomplete)         :: 49 of 54
            Pseudo Genes (internal stop)      :: 0 of 54
            Pseudo Genes (multiple problems)  :: 2 of 54
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:09:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 71801
            Orig. end                         :: 93882
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADDUE010000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22081
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="2"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22081
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22081
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12081](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12081
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    64..77
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     misc_feature    217..231
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.76"
                     /tool="antismash"
     misc_feature    221..236
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.62"
                     /tool="antismash"
     misc_feature    228..241
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.59"
                     /tool="antismash"
     misc_feature    complement(229..242)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.19"
                     /tool="antismash"
     misc_feature    229..243
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.17"
                     /tool="antismash"
     misc_feature    complement(230..243)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.87"
                     /tool="antismash"
     gene            400..1056
                     /locus_tag="INP57_RS25295"
                     /old_locus_tag="INP57_25310"
     CDS             400..1056
                     /EC_number="1.5.1.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013756.5"
                     /locus_tag="INP57_RS25295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25310"
                     /product="flavin reductase family protein"
                     /protein_id="WP_200072847.1"
                     /transl_table=11
                     /translation="MKYSPSTEKNPLPYSPFKSCTVPRPIGWLSSISTDGAENLAPYSQ
                     WQNLTFDPPMVMFSANQYPDGRRKDTVRNAEQTGWFVWNMATWDLRDAVNISAMELSPH
                     ESEFDRAGVTRSEADLAPGPMVAESPCHFECRYLSTQRLPGESNVGTVDVVFARVERIH
                     VDDSVIGDNGKLDIRTIQPIARMGYFDYTVITETFEMRVPGSSAEAQYGLQGQSA"
     gene            1344..2390
                     /locus_tag="INP57_RS25300"
                     /old_locus_tag="INP57_25315"
     CDS             1344..2390
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013740.5"
                     /locus_tag="INP57_RS25300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25315"
                     /product="AI-2E family transporter"
                     /protein_id="WP_200072848.1"
                     /transl_table=11
                     /translation="MGGGEQHEERSTVVRLGRRAWALLGIVGVLVIAWLVVSQLAVVVV
                     PVLLALFVAAALAPLVNLLGRLHVPRPLAALIAVVLGLAVIAAAVWLVVPAFVAQLPQL
                     SSALGQATEQLDRVLSRTPFFGPGVHVRAIVGSLTTQFFGGGSIPAALGTVATVLSSVV
                     LLLVVVLFYLAEGRWLAAALVGWLPAARQDEVWRVLARLWQVVGRYFRALLVVALFDAV
                     FIGAGLALLGVPLALPLAVLVYLGAFLPYLGAVLSGMLAVLVAAAERGLLTAVLVLVVV
                     LVVQQIEGNVIQPVVMGKIVRVPAFVVLVAIAIGSALLGVLGAFLAVPVAACVEHIMRH
                     LSGRTAES"
     gene            complement(2398..2880)
                     /locus_tag="INP57_RS25305"
                     /old_locus_tag="INP57_25320"
     CDS             complement(2398..2880)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="INP57_RS25305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="INP57_25320"
                     /product="hypothetical protein"
                     /protein_id="WP_200072849.1"
                     /transl_table=11
                     /translation="MDPGPDSEASHARRSARVGLQTAVIDNSAAFGFSITITSSYGALN
                     QLARAPTLLDIAGFALCAVVAFAVLQALTTHGFRRHAGAAPRSVVLLGTALDIVSVGLG
                     LGAAILAASVLPTGVAWPVGGFLASLVFALSQALELMLAARLERLRGDPEAERTQG"
     gene            2958..4289
                     /locus_tag="INP57_RS25310"
                     /old_locus_tag="INP57_25325"
     CDS             2958..4289
                     /NRPS_PKS="Domain: Aminotran_3 (24-362). E-value: 2.4e-95.
                     Score: 311.4. Matches aSDomain:
                     nrpspksdomains_INP57_RS25310_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948584.1"
                     /locus_tag="INP57_RS25310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25325"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_200072850.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.5e-83, bitscore:
                     273.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDDTAVQRHLIRYSGGGAFSPGIIDRAAGSSVFTEDGRELLDFT
                     SGQMSAILGHAHPEIVATVREQVGRLDHVYSGMLSRPVLELARRLAGTLPEPLDKAVLL
                     TTGAEANEAALRMAKLVTGGHEVVSFARSWHGMTQAAASATYSAGRVGYGPGASGNFAL
                     PVPDSFRPGIVDADGNLDWRRQLDLGFELIDAQSVGSLAACLVEPILSSGGVVDLPPGY
                     LAALRDKCHERGMLLILDEAQTGLCRTGDWYAFERDGVVPDILTLSKTLGAGLPLAAVL
                     TSAEIEQRAHDRGFLFFTTHVNDPLPAAVGNAVLDVLARDRLDLRARELGDRLRSGLAE
                     LSERHEVIGDVRGRGLLIGMELTGDPDSAGNADAPGNADEPRNADEMGAAVTRRCAELG
                     LHMNIVQLPGMGGTFRIAPPLTATESEIDRSLAILDTALKDLPG"
     aSDomain        3030..4043
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_INP57_RS25310_Aminotran_3.1"
                     /evalue="2.40E-95"
                     /label="INP57_RS25310_Aminotran_3.1"
                     /locus_tag="INP57_RS25310"
                     /protein_end="362"
                     /protein_start="24"
                     /score="311.4"
                     /tool="antismash"
                     /translation="IDRAAGSSVFTEDGRELLDFTSGQMSAILGHAHPEIVATVREQVG
                     RLDHVYSGMLSRPVLELARRLAGTLPEPLDKAVLLTTGAEANEAALRMAKLVTGGHEVV
                     SFARSWHGMTQAAASATYSAGRVGYGPGASGNFALPVPDSFRPGIVDADGNLDWRRQLD
                     LGFELIDAQSVGSLAACLVEPILSSGGVVDLPPGYLAALRDKCHERGMLLILDEAQTGL
                     CRTGDWYAFERDGVVPDILTLSKTLGAGLPLAAVLTSAEIEQRAHDRGFLFFTTHVNDP
                     LPAAVGNAVLDVLARDRLDLRARELGDRLRSGLAELSERHEVIGDVRGRGLLIGMEL"
     gene            complement(4301..4744)
                     /locus_tag="INP57_RS25315"
                     /old_locus_tag="INP57_25330"
     CDS             complement(4301..4744)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030337.1"
                     /locus_tag="INP57_RS25315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25330"
                     /product="DUF1232 domain-containing protein"
                     /protein_id="WP_233628274.1"
                     /transl_table=11
                     /translation="MSWGELLAGTAGCLVLAWVALVAALVAALATSSPSRGVLREAARL
                     LPDSLRLLRRLLADRDAPRGVRWRVGLVLGYLALPIDLVPDFIPVLGWADDVIVVTLVL
                     RSLVRRAGAPAVRRHWPGTDDGFAALCRLTGLRANSGVTAAER"
     misc_feature    complement(5017..5032)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.2"
                     /tool="antismash"
     misc_feature    complement(5019..5032)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.09"
                     /tool="antismash"
     misc_feature    5020..5033
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.78"
                     /tool="antismash"
     gene            5364..5828
                     /locus_tag="INP57_RS25320"
                     /old_locus_tag="INP57_25335"
     CDS             5364..5828
                     /GO_process="GO:1901661 - quinone metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942737.1"
                     /locus_tag="INP57_RS25320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25335"
                     /product="MSMEG_3727 family PQQ-associated protein"
                     /protein_id="WP_200072852.1"
                     /transl_table=11
                     /translation="MTATADDRQAELTAAGLCGQNKATLGRMLGTGNVEHAEEGPDGRM
                     RATVRIREDELCWDPATIILPHGGDLELTVINDDKNTHCAVLPSNGDNMIIWLVNHSKG
                     TADLRLQGPGYYWYSSTTGNDEGRGLTGAIVVSGDVPKHARLDRPAQPRP"
     gene            5842..7524
                     /locus_tag="INP57_RS25325"
                     /old_locus_tag="INP57_25340"
     CDS             5842..7524
                     /EC_number="1.1.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010241631.1"
                     /locus_tag="INP57_RS25325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25340"
                     /product="PQQ-dependent dehydrogenase, methanol/ethanol
                     family"
                     /protein_id="WP_200072853.1"
                     /transl_table=11
                     /translation="MTDYVDAGQAVPLGTLSNVKGSAPATGNVDYERVRNARSEPQNWL
                     TYYGTYDGQRYSSLDQISKDNVKSLSPAWVFQAGSTGLHSGASTYSFEAAPIVVEGIMY
                     VSGPDGKVWALDAETGEELWRYKHASPFDVSLCCGNVNRGVAVGHGKVYLATLNAHLVA
                     LDARTGEPVWDVTIGDVRAGESRTVAPLLVKDMVLVGSSGGEFGTRGNLDAFDAHTGER
                     RWRCYTIPKPGEPGSETWPADGEAWQRGGGNCWVTPTYDPDLNLIYQGTGNPAPDFDGA
                     VRPGDNLYTDCVIAVDADTGEIRWHYQFTPHDLWDYDSTMENLLFEHEGRKLLAHADKN
                     GYFFVLDAVNGELVRVFPFVDRITWGEISPEGEVTAKVYPDAEGVPVHFWPGPAGGKEW
                     THMAYSPQTGLIYVPVQEVGATATRRRREFKESIPYWGAGVAVDLDDHYGYVAAIDPLT
                     GEEKWRWRNEYPMCASVLTTAGGLVFTGLPTGEFVALDAVTGEKVWQFQCGSGHHSSPT
                     TYSVDGRQYIAVPTGWGGWIEGFLPGLLGGSAGDALFSFALPE"
     gene            7658..7873
                     /gene="rd"
                     /locus_tag="INP57_RS25330"
                     /old_locus_tag="INP57_25345"
     CDS             7658..7873
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_process="GO:0072592 - oxygen metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334408.1"
                     /locus_tag="INP57_RS25330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25345"
                     /product="rubredoxin"
                     /protein_id="WP_200072854.1"
                     /transl_table=11
                     /translation="MSTDRTLAQPQTRRWICELCGWVYDPEEGDPDGGIPPGTRFEEIP
                     DDWMCPICGATKSDFRELEPGEQIPM"
     gene            7921..8682
                     /locus_tag="INP57_RS25335"
                     /old_locus_tag="INP57_25350"
     CDS             7921..8682
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334407.1"
                     /locus_tag="INP57_RS25335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25350"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_200072855.1"
                     /transl_table=11
                     /translation="MIAGYDHFVTLADSLQWDEFALDLDADVQAWPRLRDAERTQLLGL
                     TAGFCIGENSVAGELGSFQVAAGDESMAAAFRAQERDEKRHARFFDRVAAEVAAVPGAD
                     VPARLDVLREHVSPEIVELFEKRLPAIAKQLADDHSGLVPAVGLYHMILEGVVLLAAQH
                     AMLDALEHLSVQLPGLHKGMELVLRDERWHIGFGSRVIQNAEILDDEMEELLRAGEQAS
                     SAWGELISPDAIEKTAQLHRRRLKAVNIKFW"
     gene            8882..8977
                     /gene="pqqA"
                     /locus_tag="INP57_RS25340"
                     /old_locus_tag="INP57_25355"
     CDS             8882..8977
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942740.1"
                     /locus_tag="INP57_RS25340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25355"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_200072856.1"
                     /transl_table=11
                     /translation="MESETPQWEPPRFEEIGCAAEVTMYVAQVED"
     gene            9105..10004
                     /gene="pqqB"
                     /locus_tag="INP57_RS25345"
                     /old_locus_tag="INP57_25360"
     CDS             9105..10004
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010696861.1"
                     /locus_tag="INP57_RS25345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25360"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_200072857.1"
                     /transl_table=11
                     /translation="MLVRVLGSAAGGGFPQWNCGCPCCRAVREGSRPCLPRTQSSIAIS
                     ADHEQWFLVNASPDVRAQLEASPALLPAAGRATPLQGVLLTDAELDHALGLLLLREAES
                     LELHATAAVHETLRTDNSLLATLQAYCPVKWREVVPGEDVALGNGLSYRAFDVPTTKRS
                     RFGPDRGPGRVVGYRFTDERSGRAAVCLPGVQEITGQVREQLRDCTGLFIDGTCFSDDE
                     MPRLGLASKTSREMGHLPMSGPGGSLEQLAELPIERKIYVHLNNTNPVLLDDSPERREV
                     ERLGFEIATDGTEVQIRP"
     gene            10001..10708
                     /gene="pqqC"
                     /locus_tag="INP57_RS25350"
                     /old_locus_tag="INP57_25365"
     CDS             10001..10708
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018334405.1"
                     /locus_tag="INP57_RS25350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25365"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_200072858.1"
                     /sec_met_domain="TIGR02111 (E-value: 9.4e-105, bitscore:
                     342.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALDETRTSAGTEEFVAALRAHAQRYHHQHPFHVRMNEGRLSRE
                     QIRGWVANRYYYQECIPIKDAAILSNCPDPAVRRRWIRRILDHDGTADEPGGIEAWLRL
                     AEAVGLSREEVRDERHVVPGVRFAVDAYVTFARTRPWTEAVASSLTELFAPDLMSRRLA
                     AFEQHYFWVDRDGLAYFRNRLEQAPRDSEHGLQVTTERCRSAAEQERALAALSFKCDVL
                     WSMLDAIDQAHPG"
     gene            10680..11000
                     /gene="pqqD"
                     /locus_tag="INP57_RS25355"
                     /old_locus_tag="INP57_25370"
     CDS             10680..11000
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010696864.1"
                     /locus_tag="INP57_RS25355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25370"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_200072859.1"
                     /sec_met_domain="PqqD_RRE (E-value: 4.6e-22, bitscore:
                     70.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3e-15, bitscore: 49.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTKPTPAEPARLPDSARPHLTTGLRLTFDEVRARHVLLGPESV
                     LVLNPTGAAILRLCDGRRDIGELIAELQAQFAGVEPGEVRAFLDHLAAKRCVEAAHDRH
                     DS"
     aSDomain        10728..10973
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_INP57_RS25355_PqqD_RRE.1"
                     /evalue="9.00E-23"
                     /identifier="RREFam006.1"
                     /label="INP57_RS25355"
                     /locus_tag="INP57_RS25355"
                     /protein_end="98"
                     /protein_start="16"
                     /score="70.8"
                     /tool="antismash"
                     /translation="SARPHLTTGLRLTFDEVRARHVLLGPESVLVLNPTGAAILRLCDG
                     RRDIGELIAELQAQFAGVEPGEVRAFLDHLAAKRCVE"
     gene            10990..12081
                     /gene="pqqE"
                     /locus_tag="INP57_RS25360"
                     /old_locus_tag="INP57_25375"
     CDS             10990..12081
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010696866.1"
                     /locus_tag="INP57_RS25360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25375"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_200072922.1"
                     /sec_met_domain="PF04055 (E-value: 2.9e-24, bitscore: 79.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.1e-07, bitscore: 24.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1e-09, bitscore: 32.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.8e-10, bitscore:
                     32.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPSPFGLLAELTYACPLHCAYCSNPLNLADYRDELSTADWQRVL
                     REARDLGVLQLHLSGGEPLQRRDIVEIVRTGSELGMYTNLITSALGLSRRRAEELRATG
                     LDHVQISVQADEPATSDRIAGTRSFARKAEAARMVKELGWPLTVNVVLHRQNLDRIAEI
                     VALAEELGADRLELANTQYYGWAWRNRDVLLPSRDQIERAEQVVRSERERLPHMEIIHV
                     LPDYYSQYPKACMGGWAQRQLTIAPNGDALPCPAAQSLPLPRESVRERPLARIWQESPL
                     FEAFRGTDWMPEPCRSCSRRDVDFGGCRCQAFQLTGDAARTDPVCHLSPDRELVDQAVR
                     AANASEETVRGELTPRPHPRDQR"
     gene            complement(12086..13195)
                     /locus_tag="INP57_RS25365"
                     /old_locus_tag="INP57_25380"
     CDS             complement(12086..13195)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010241622.1"
                     /locus_tag="INP57_RS25365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25380"
                     /product="sodium:calcium antiporter"
                     /protein_id="WP_200072860.1"
                     /transl_table=11
                     /translation="MIPVVEFALGIALLVYSAEKLIGFLVGVASRWAVSLFLIAVVFTG
                     IEFDDLAFGIVLNVDELEHVALGTVIGTTIAMTGIVLALAALIAPCRVDVPKDYLALFV
                     AGPVVLWALALTGALTSVTGIVLLVLFVAFVCWIGYREYTSRRPVFRNAELYEQVEKVG
                     TRTGAAATPTAAAAESDDAADDAGPSGSGGLALPNDLRVDQGFVQARQRPLWAGLALAV
                     LALAGLVVGASIAGQGTDGILDEFGIDGTVFGVTIATLVLSLEDLFLTVEPARRGAPEI
                     GVANVIGSIVFSVTGKLGIVLLVGGAITVNANVLSWHLPVLLVMTVLSAIFLATGRLRR
                     WHGAVLLALYIGYFVISLMAFGEVPLDSD"
     gene            13467..13988
                     /locus_tag="INP57_RS25370"
                     /old_locus_tag="INP57_25385"
     CDS             13467..13988
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020499922.1"
                     /locus_tag="INP57_RS25370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25385"
                     /product="SRPBCC family protein"
                     /protein_id="WP_200072861.1"
                     /transl_table=11
                     /translation="MSVANLHERTFTVQPQAVGALLDALAAEGDPTWPGDIWPALRLDR
                     PLGIGATGGHGPIRYHVVAYVPGQRVRFRFDRPHGFDGFHEFIVLPDHDGTVLQHKIAM
                     RVRGPALLTWPLVFGPLHDALLEDLLDRAEEHLTDGVARRARWSWWVRVLRRLSMPRRK
                     TSRAQAGESA"
     gene            complement(14055..14903)
                     /locus_tag="INP57_RS25375"
                     /old_locus_tag="INP57_25390"
     CDS             complement(14055..14903)
                     /NRPS_PKS="Domain: Abhydrolase_1 (41-144). E-value:
                     5.1e-16. Score: 51.0. Matches aSDomain:
                     nrpspksdomains_INP57_RS25375_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="INP57_RS25375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25390"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_200072862.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-12, bitscore: 41.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.6e-19, bitscore:
                     63.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDLAGWGGGTEGGVVFAERVRWNGVVVEVAGPDPEPADDRPPVV
                     LLHGGCHGAWCWRQWSSVLAAAGWRTYAPNWFGRFGSAPVADALGRSLRSVADAGGELS
                     RVLDRLRRPAVLIGHSMGGFACLDWACRHGNVAALVLVAPVVPRGFGAEPIPVRPRPDR
                     LWRPPDVSTATSMFFDHLDLDDDAGRATARAWARTLVGESPVAVLDAVRFRLPVDVDPL
                     RCPVRIVAGERDPLVPVSALRELADHVGAHLNVLDCGHGIPLLPGTAAAEATAAWLNEQ
                     C"
     aSDomain        complement(14472..14780)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_INP57_RS25375_Abhydrolase_1.1"
                     /evalue="5.10E-16"
                     /label="INP57_RS25375_Abhydrolase_1.1"
                     /locus_tag="INP57_RS25375"
                     /protein_end="144"
                     /protein_start="41"
                     /score="51.0"
                     /tool="antismash"
                     /translation="PPVVLLHGGCHGAWCWRQWSSVLAAAGWRTYAPNWFGRFGSAPVA
                     DALGRSLRSVADAGGELSRVLDRLRRPAVLIGHSMGGFACLDWACRHGNVAALVLVAP"
     CDS_motif       complement(14520..14570)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_INP57_RS25375_0001"
                     /evalue="8.20E-04"
                     /label="NRPS-te1"
                     /locus_tag="INP57_RS25375"
                     /protein_end="128"
                     /protein_start="111"
                     /score="12.0"
                     /tool="antismash"
                     /translation="RPAVLIGHSMGGFACLD"
     misc_feature    15029..15042
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.89"
                     /tool="antismash"
     misc_feature    15201..15215
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.42"
                     /tool="antismash"
     gene            15235..15948
                     /locus_tag="INP57_RS25380"
                     /old_locus_tag="INP57_25395"
     CDS             15235..15948
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667283.1"
                     /locus_tag="INP57_RS25380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25395"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_200072863.1"
                     /transl_table=11
                     /translation="MAIPAYLRIRTELEQQIQSGALAPGTRLPTEAELQQRYSVGRATA
                     QRVLTELSRAGLVERHRRRGTFVADGARQENLLRMVHPALHGPEIPGPHAVDSAMVIPA
                     EDADVALPGITGDAPVNQLRRLKFDVEHNPIAVELAAVPFSLAPRLFDENLEHLTVHDY
                     FARNRIPVAKSRVYVDPIPLDAATAARFGTEPGRAVIRLRRLTWLTGGGLAEAMWHIIR
                     PDLVEFFVEQSVLAT"
     gene            16055..17188
                     /gene="solA"
                     /locus_tag="INP57_RS25385"
                     /old_locus_tag="INP57_25400"
     CDS             16055..17188
                     /EC_number="1.5.3.2"
                     /GO_function="GO:0050131 - N-methyl-L-amino-acid oxidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="solA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011873897.1"
                     /locus_tag="INP57_RS25385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25400"
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="WP_200072864.1"
                     /sec_met_domain="DAO (E-value: 2.1e-43, bitscore: 142.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPRVAVVGTGVIGAMTAWRLARRGADVIALDALSPGHDRGASA
                     GESRIFRTLYKEGSGYVPLLQRSGALWRELELSTGTRLLTMCGGLTIGPREHADVRAVR
                     RCAEEHDLDHEVLDTAAARQRFAQHRIDDDEIMVFDPAAGVLRPEPAVQAALHAAGLAG
                     ASILPYHRVDDVAETARGWRITSGATHFDVDHVVFAPGPWARQLDPLSTLPVEIRLITA
                     YWFATRDTAAHRPDRLPIAIRRHRDAGFSCFPVLDGVGIKIIPHHLGWPVLHDPAALPR
                     SAEPEYARAASEAARRLLPGVVPHPVRIGTYAEGFTPDEHALLGPLPGHRNATVMTGFS
                     GHGFKLAPVFGELGAELALGEPASHDITALDPGRRAD"
     gene            17221..18654
                     /locus_tag="INP57_RS25390"
                     /old_locus_tag="INP57_25405"
     CDS             17221..18654
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667285.1"
                     /locus_tag="INP57_RS25390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25405"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_200072865.1"
                     /transl_table=11
                     /translation="MPTGSTAQIAGVVLASLLVIGFGVAMSVHFGRKAKTAQDWLSAGE
                     SLPLVVVIITQFATATGGGVLIAHVGIGYRSGWSVFAYEGCVLVGFLGLMLIAKWLRQQ
                     RFTTVPDVVTRLFGRHRMVTAIAALAALVVPFGWLATQFVAFAQLFGRLTGMPDAALIV
                     VIMLASLLFVLPGGMTSVAWTDFVFGILMIVLSLGVAAYAVDLAGGWRQITETVPRQLW
                     GWGGFTAAGGEQLWLWIAAIVPGTLTNQLYYQRVFATKKVSDARRGLALSGLTMLIGGV
                     YAGCIGLAVHSLNPGLTNEEDAAGWLLTRLPSWLVVVFGAFLVSTIVSTTGAALQSVVA
                     NLTRDVYHNIVGGEHDERRTVRLSRTITVAVSLLAAVLAILFPKALTWLVATYAYSAAA
                     LAAPIFLGYLLHRRRRLTPATAIASMIAGVAGCAAAQLADTTVPYAVYGIAASAAVLLV
                     LAMLAPADRDQTPHAGVRS"
     gene            18657..19817
                     /locus_tag="INP57_RS25395"
                     /old_locus_tag="INP57_25410"
     CDS             18657..19817
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949649.1"
                     /locus_tag="INP57_RS25395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25410"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_200072866.1"
                     /sec_met_domain="DAO (E-value: 2e-42, bitscore: 139.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIAVIGLGVLGASAARSLSLAGAEVTVFERSGALAGTSGTSFAW
                     TNSHNKNPRAYHDLNVAGMAEHEALAADPGPHRRWFARTGNLEWAADEAGTERLAASVA
                     ELAARDYPVGWITPGRARELVPDLRVPAGIEDIAYYPTEGHVVPALLLARLWGQARDLG
                     ARLRCPAEVLGLSEVERGVRIELADGTAEADAVVLAAGRWTEELSAAAGCRIPMAAPDA
                     AGSATVGLLGYTSPLPVRMDRVLTTPKLNVRPDGGGRLVVQGLDLDADADPAAPPAVNG
                     RHAQELRGRLTELLGQAAGLESLRVGQRAMPADGLTVAGFLGGSGRIYAMATHSGITLG
                     PLLGKLAAQEITTGDPAEALAPFRPDRLIGRSGLPPLTPARFAGQQ"
     gene            complement(19954..20358)
                     /locus_tag="INP57_RS25400"
                     /old_locus_tag="INP57_25415"
     CDS             complement(19954..20358)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010230610.1"
                     /locus_tag="INP57_RS25400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25415"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_200072867.1"
                     /transl_table=11
                     /translation="MQITRSSSMDTQQGPADWFTGDVYIDAVAAPAAGSAFGAANVHFT
                     PGARTAWHTHPHGQTIFVTEGVGLCQREGGPVETVHPGDRVFFEPGENHWHGAAPNRFM
                     VHVAMQQNDESGNPVTWGRHVTDEEYDAAR"
     gene            complement(20659..21321)
                     /locus_tag="INP57_RS25405"
                     /old_locus_tag="INP57_25420"
     CDS             complement(20659..21321)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.5"
                     /locus_tag="INP57_RS25405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_25420"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_200072868.1"
                     /transl_table=11
                     /translation="MSRQASMSERAYASLKRDILRCRLRPGEVIMDGPLAEQYGMSRTP
                     IREAMNALRREGLVVVVPRRGTFVKSVDIGELQDTYHMRTLLEPEAAVLASQRSTAAEL
                     DALEELSDSTVRAADEPAARHEANRLFHVRIAELGRIPLMTQTINALHEEIERFLNLQG
                     ALGHPYTATNHQRLVDIIRTDSADEIRAVVLAGIEKARTHMIETLIARPDSAGTRAD"
ORIGIN
        1 cgggtcgtga cgtccgcggg cagcgcccgc tcgtcgaaga acggtccccg cgaggtgccg
       61 ccacgcatga acaggcacgg gatcgcggtc tgcgaaccgc ggcggcgcga gcgcgcggcg
      121 gggccgtcgg cgtcgacggg catggcactc ctccatcgag tcgtcgcgag cgcgaggtcc
      181 ttcatcggct ctccggcaag ctagactatg aacacgattg ttcacaatct tttcgacaaa
      241 attcctcgcc atcttgcgca tcgcgtgcga tcggcttgcg ccgggacgag cggcgatcac
      301 ggcggcacta cgctcggacc gcgccgcggc accgtggacg cggccactgc cggcggcccg
      361 tgacctggcc gcccggccgg cgacgcacaa ggagcacctg tgaagtacag cccctcgacc
      421 gagaagaatc cgctgcctta ctcgccgttc aagagctgca ccgttccccg gcccatcgga
      481 tggctctcca gcatcagcac cgacggcgcc gagaacctcg cgccctacag ccagtggcag
      541 aacctgacct tcgatccccc gatggtcatg ttctcggcca accagtaccc cgacggacgc
      601 cgcaaggaca ccgtccgcaa cgccgagcag acgggctggt tcgtctggaa catggccacc
      661 tgggacctgc gcgatgccgt caacatcagc gcgatggagc tgtccccgca cgagagcgag
      721 ttcgaccggg cgggagtcac ccgctccgag gcggacctgg cgcccgggcc gatggtcgcc
      781 gaaagccctt gccacttcga gtgccggtac ctgtccacgc agcggctgcc cggcgagagc
      841 aacgtcggca ccgtcgacgt ggtcttcgcc cgcgtcgaac gcatccacgt cgatgactcg
      901 gtcatcggcg acaacggcaa gctggacatc cggaccatcc agccgatcgc ccgcatgggc
      961 tacttcgact acaccgtcat caccgagaca ttcgagatgc gcgtccccgg ttccagcgcg
     1021 gaggcgcagt acggcctcca agggcagtcg gcctgactgc tcaggccccg cgcgccgagg
     1081 cttcgcgccg ggcctgctcc ggccccgccg atgccgggcc tgagtcagcg ttcgcgccac
     1141 ctcggcgtca gtccttccgg cctcgcgacg accgagcacg ttgatgcgcc ttggtgcacc
     1201 atcgcctccg tgcccggcag cagggaggtc accgtggtcc aaccgcaggt cgcagaacga
     1261 cgtggccgct gaccggggcc gtgcgccggt gacgcggcca cgtcgccccg cacgctcgta
     1321 ctcgcggaag tgagctcgtc gtgatgggcg gcggtgagca gcacgaggag cgatcgaccg
     1381 tggtccggct cggccgcagg gcgtgggcat tgctgggcat cgtcggcgtg ctcgtcatcg
     1441 cctggctggt cgtctcgcag ctcgcggtcg tggtggtgcc ggtgctgctg gcgctgttcg
     1501 tcgccgccgc gctggctccg ctggtgaacc tgctcggccg gctgcacgtg ccgcggccgc
     1561 tggccgcgct gatcgcggtc gtgctcgggc tcgcggtgat cgcggcagcc gtctggctcg
     1621 tggtgcccgc cttcgtcgcg cagctcccgc agctgtcctc cgcgctgggg caggcgaccg
     1681 agcagctcga ccgggtgctc tcccgcacgc ccttcttcgg cccgggtgtg cacgtgcggg
     1741 ccatcgtcgg aagcctcacg acgcaattct tcggcggcgg ctcgatcccg gccgcgctcg
     1801 gcaccgtggc cacggtgttg tcctcggtcg tgctgctgct ggtggtggtg ctgttctacc
     1861 tggccgaggg gcgttggctc gcggctgcgc tggtcggctg gctgcccgcg gcgcggcagg
     1921 acgaggtttg gcgggtgctg gcgcggttgt ggcaggtcgt cggccgctac ttccgcgcgc
     1981 tgctcgtcgt cgcgctgttc gacgcggtgt tcatcggcgc cggcctggcg ctgctgggtg
     2041 ttccgctggc gctgccgctg gccgtgctgg tctacctggg cgctttcctg ccttacctcg
     2101 gggccgtgct ctcgggaatg ctggcggtgc tggtcgcggc ggccgagcgc ggactgctca
     2161 ccgccgtgct ggtgctcgtg gtcgtgctgg tcgtgcagca gatcgaaggc aacgtgatcc
     2221 aacccgtggt gatgggcaag atcgttcgcg tgcccgcgtt cgtggtcctg gtggccatcg
     2281 ccatcgggtc cgcgctgctg ggcgtgctgg gcgccttcct cgcggtgccg gtcgcggcct
     2341 gcgtcgagca catcatgcgg cacctcagcg gacgcactgc ggagagctga gccgcgctca
     2401 gccctgcgtt cgctccgctt ccgggtcgcc gcggagcctt tccagccgag ccgcgagcat
     2461 gagctcgagc gcctggctga gcgcgaagac cagcgaggcc aggaacccac ccaccggcca
     2521 cgccacaccg gtgggcagca ccgacgctgc caggatcgcc gccccgagcc cgagaccgac
     2581 cgaaacgatg tccaatgcgg tccccagcag gaccaccgat cgaggcgccg cgccggcgtg
     2641 gcgacggaac ccgtgggtgg tcaacgcctg cagaacggcg aacgccacga ccgcgcacag
     2701 cgcgaacccc gcgatgtcga gcagcgtcgg cgctcgtgcc agctggttga gcgccccgta
     2761 cgacgaggtg atcgtgatgg agaaaccgaa cgccgcgctg ttgtcgatca cggcggtctg
     2821 cagtcccacg cgggcgctgc gcctggcgtg ggaggcttcg ctgtccggcc ccggatccat
     2881 gagcgcacgg taagggatcc gggacgatcg tgatcggcga tggacgcccg aacggcgccg
     2941 tttgtagcgt cggggccatg tccgacgaca ccgctgtgca acggcacctg atccgctact
     3001 cgggcggcgg cgccttcagc cccggaatca tcgatcgcgc cgcgggcagt tcggtgttca
     3061 ccgaggacgg gcgcgagctg ctcgacttca cctcggggca gatgagcgcg atcctcggcc
     3121 acgcgcaccc ggagatcgtc gcgacggtcc gggagcaggt gggccgcctg gaccacgtct
     3181 acagcggcat gctcagccgc ccggtcctcg agctggcccg gcggctggcg gggacgctgc
     3241 cggagccgct ggacaaggcg gtgctgctca cgaccggtgc cgaggcgaac gaagccgccc
     3301 tgcggatggc caagctcgtc accggcgggc acgaggtcgt ctcgttcgcc cgctcctggc
     3361 acggcatgac gcaggccgcc gcgagcgcca cctacagcgc cgggcgcgtc ggctacgggc
     3421 ccggcgccag cggcaacttc gcgctgcccg tcccggacag cttccggccc ggcatcgtcg
     3481 acgccgatgg gaacctggac tggcgccgcc agctcgacct cggcttcgag ctgatcgatg
     3541 cgcagtcggt cggcagcctc gcggcctgcc tggtcgagcc gatcctgagc tccggtggcg
     3601 tcgtcgacct cccgcccggc tacctggccg cgctgcggga caagtgccac gagcggggca
     3661 tgttgctgat cctggacgag gcgcagaccg ggctgtgccg taccggcgac tggtacgcgt
     3721 tcgagcgcga tggcgtcgtc ccggacatcc tcacgctgtc caagaccctc ggcgcagggc
     3781 tgccgttggc ggcggtgctc accagcgccg agatcgagca gcgagcccac gaccgcgggt
     3841 tcctgttctt caccacgcac gtcaacgacc cgctgcccgc cgccgtcggg aacgcggtcc
     3901 tggacgtgct cgcccgcgac cgcctggacc ttcgcgcccg cgaactcggc gaccggctgc
     3961 gcagcggact tgccgagctc agcgagcggc acgaggtgat cggggacgtc cgcggccgcg
     4021 gactgctgat cgggatggag ctgaccggcg accccgattc agccgggaac gccgacgcgc
     4081 ccggaaacgc cgatgagccc aggaacgccg atgagatggg tgccgcggtg acccggcgct
     4141 gcgccgagct cggcttgcac atgaacatcg tgcagctgcc gggtatgggc gggacgttcc
     4201 gcatcgctcc gccgctgacc gccaccgaat ccgagatcga ccgcagcctc gcgatcctcg
     4261 acaccgccct gaaggacctg ccgggctgac gttgctcgcg tcaccgctcc gcggccgtga
     4321 cgcccgagtt cgcccgcagc ccggtgagcc ggcacagcgc ggcgaagccg tcatcggtcc
     4381 cgggccagtg cctgcgcacc gcgggcgcgc ccgcacggcg cacgagcgag cgcagcacca
     4441 gcgtgacgac gatgacgtcg tcggcccagc cgagcaccgg gatgaagtcg ggcacgaggt
     4501 cgatcgggag cgcgaggtag cccagcacca gcccgacgcg ccagcgaaca ccacgcgggg
     4561 cgtcccggtc ggccagcagc cgccgcagca gccgcagcga gtcgggcagc aaccgcgccg
     4621 cctcccgcag cacgccccgg ctcggactcg aggtcgcgag cgcggcgacg agcgcggcga
     4681 cgagcgcgac ccaggccagc accaggcacc cggcggtgcc cgctagcaac tcgccccagc
     4741 tcaatgcgtt cacgtcggct ctcccgtcgg ggctcgggcg tgcgggactg ctccgcagtg
     4801 taggcagcgc cgcgcgcggc tcggacgact cgccgggacc gcggaagccg ggctgcggcc
     4861 gaacgccgtc ggagggcccg ggcgccatcg aaaccgggcg ccaccgaagc ggggcgccac
     4921 cgaagggcag cgcgccaggc gcgagccttc ccacgtccag gctaccgggc ggcaactcgt
     4981 gatcaatcga gagccggttc agcaataagg cacagcagtg atcctgatta caacctcgct
     5041 gccctgggtt attgttgatg tgatgcgcag cacgctcgag aggtggcgag tgacctgtgc
     5101 tgtccgagaa cggacggtcg cggctcctgc tcggcgtaga cgagcggtgg ctgcctgccc
     5161 acttcggtcc ggccgggtgc tgacgttccg ggaaccaacg gtccggtgtg gacaccaggg
     5221 atcacgggcg agcgagtccg ccgcggcttt ccggaatcgg cgtgctgggt tcggcgacga
     5281 gaggcggttt tcgtgagcag cgagatcaag cgcacgcgtg atcacgggtg tggcgcacac
     5341 gtgcacagca ggaggtggga ccgatgacgg ccactgcaga cgatcggcaa gccgaattga
     5401 ccgcagcggg cctgtgcggc cagaacaagg cgacgctggg gcggatgctc ggcaccggga
     5461 acgtcgagca cgccgaggag ggtccggacg gccggatgcg cgccacggtc cggatccggg
     5521 aggacgaact gtgctgggac ccggcgacga tcatcctgcc gcacggcggt gacctcgagc
     5581 tcacggtcat caacgacgac aagaacacgc actgcgcggt gctgcccagc aacggcgaca
     5641 acatgatcat ttggttggtg aaccactcca agggcacggc cgatctccgg ctgcaagggc
     5701 ccggttacta ctggtacagc tccacgaccg gcaacgacga aggccgcggc ctcaccggcg
     5761 cgatcgtcgt cagcggcgac gtccccaagc acgcccggct cgaccgtccc gcccagccgc
     5821 gcccgtagac aggagcacat catgaccgac tacgtcgatg caggtcaggc cgtcccgctc
     5881 gggacgctca gcaacgtcaa gggcagcgcg cccgccaccg ggaacgtcga ttacgagcgc
     5941 gtgcgcaacg cccggtcgga gccgcagaac tggctgacct actacggcac ctacgacggt
     6001 cagcgctaca gcagcctgga tcagatcagc aaggacaacg tcaaaagcct ttcgcccgcc
     6061 tgggtgttcc aggccggttc gacggggctg cactccggcg cgtcgaccta ctccttcgaa
     6121 gccgccccca tcgtcgtgga gggcatcatg tacgtgtccg gcccggacgg gaaggtctgg
     6181 gcgctggatg cggagaccgg cgaagagctc tggcgctaca agcacgcctc ccccttcgac
     6241 gtctcgctgt gctgcgggaa cgtcaaccgc ggcgtggccg tggggcacgg caaggtctac
     6301 ctcgccacgc tcaacgccca cctggtggcg ctggacgccc ggaccggcga gcccgtctgg
     6361 gacgtgacca tcggcgacgt gcgcgccggg gagagccgca ccgtggcgcc gctgctggtc
     6421 aaggacatgg ttctggtcgg cagctcgggc ggggagttcg gcacccgcgg gaacctagac
     6481 gcgttcgacg cgcacaccgg ggagcgccgc tggcgctgct acacgatccc caagcccggt
     6541 gagcccggat ccgaaacctg gcccgccgac ggcgaggcgt ggcaacgcgg cgggggcaac
     6601 tgctgggtca cccccaccta cgatccggac ctgaacctga tctaccaggg caccggcaac
     6661 ccggcaccgg acttcgacgg cgccgtgcgt cctggcgaca acctctacac cgactgcgtc
     6721 atcgccgtgg acgccgacac cggcgagatc cgctggcact accagttcac cccgcacgac
     6781 ctgtgggact acgactccac gatggagaac ctgctgttcg agcacgaggg gcgcaagctg
     6841 ctcgcgcacg cggacaagaa cggctacttc ttcgtcctgg acgcggtcaa cggcgagctg
     6901 gtccgggtgt tcccgttcgt cgaccggatc acctggggcg agatcagccc cgaaggcgag
     6961 gtcaccgcca aggtctaccc ggacgcggaa ggcgtgccgg tgcacttctg gccgggaccg
     7021 gccggaggca aggaatggac gcacatggcc tacagcccgc agacggggct gatctacgtg
     7081 ccggtgcagg aagtcggggc caccgccacc cgccgacgcc gcgagttcaa ggaaagcatc
     7141 ccgtactggg gcgcgggagt cgccgtggac ctcgacgacc actacgggta cgtggccgcc
     7201 atcgacccgc tcaccggcga ggagaagtgg cgctggcgca acgagtaccc gatgtgcgcc
     7261 tcggtgctga ccacggcggg cgggctggtg ttcaccggac tgcccacggg tgagttcgtc
     7321 gccctggacg ccgtgaccgg cgagaaggtg tggcagttcc agtgcggcag cgggcaccac
     7381 agcagcccga ccacctacag cgtcgacggc cgccagtaca tcgcggtccc gaccggttgg
     7441 ggcggctgga tcgagggctt cctgcccggg ctgctcgggg gctcggcggg cgacgcgctg
     7501 ttctccttcg cactgccgga gtaagaccgc agcggggcgt cggctcggaa ccgacgcccc
     7561 gcgaggtccc gatcgactcg agaggacggg acaccgtgca actccacggc cgcgacgacg
     7621 gcggggtcgc ccggctgccc ggggaaccgg cgagcgcatg agcaccgatc gaacattggc
     7681 gcagccgcag accaggagat ggatctgcga gctctgcggc tgggtttacg accccgaaga
     7741 aggcgacccc gacggcggca tcccgccggg gacgcgcttc gaggagatcc ccgacgactg
     7801 gatgtgcccg atctgcgggg cgacgaagtc ggatttccgc gagctcgagc cgggcgagca
     7861 gatcccgatg tagtgcgacc cccgatgcaa tgaggccccg acgcatgagg acgctgatcg
     7921 atgatcgccg ggtacgacca cttcgtcacc ctcgccgatt cgctgcagtg ggacgagttc
     7981 gccctcgacc tcgacgccga cgtccaggcg tggccccgat tgcgggacgc ggagcgcacc
     8041 cagctgctcg gactgacggc cggcttctgc atcggtgaga actcggtcgc gggcgagctc
     8101 ggttcgttcc aggtcgccgc gggcgacgag tcgatggcgg cggccttccg cgcgcaggag
     8161 cgcgacgaga agcggcacgc gcggttcttc gaccgcgtcg cggccgaagt ggccgccgtc
     8221 ccgggagccg acgtcccggc ccggctcgac gtgctgcgcg agcacgtcag ccccgagatc
     8281 gtggagctgt tcgagaagcg gctgcccgcc atcgccaagc agctcgccga cgaccactcg
     8341 gggctggttc ccgcggtcgg gctctaccac atgatcctcg agggcgtggt cctgctggcg
     8401 gcccagcacg ccatgctcga cgcgctcgag cacctgtcgg tgcagctgcc ggggctgcac
     8461 aagggcatgg agctggtcct gcgcgacgag cgctggcaca tcgggttcgg ctcgcgggtc
     8521 atccagaacg ccgagatcct cgacgacgag atggaggaac tgctgcgggc gggcgagcag
     8581 gcatcctccg cgtggggaga gctgatctcg cccgatgcca tcgagaagac cgcgcaactg
     8641 caccggcgca ggctcaaagc cgtcaacatc aagttctggt gagcgtgcgc cctcggcgag
     8701 cgtgctcgct aacgccgcac gacagctccg agccatccgg agcactcgat tcccggtccg
     8761 cagcagcgcg atcgacacga gcgctgctca ttacaagcac ggtgcacctc ggctatggtc
     8821 gatgtgacac acagcaccta tggcacggcg ctgtcgtgca gctgaaaggg ggtgcagaca
     8881 tatggagtcg gaaaccccgc aatgggagcc gccccggttc gaggaaatcg gttgcgcggc
     8941 cgaggtgacg atgtacgtcg cccaggtcga agactgaaac cggcgagcgt ttctcgaggc
     9001 caccacggac atcggcccgc cggtgcccgc ggtggccgcc tcgccgccgg agccgcgaga
     9061 gtcgccgcaa cctcccggat caactgtgga cacaaggagt cggcgtgctg gtgcgagtgc
     9121 tgggttctgc ggcgggaggc ggtttcccgc agtggaactg cggatgcccg tgttgccggg
     9181 cggtgcggga gggttcccgg ccgtgcctgc cacgcaccca gtcatcgatc gcgatcagcg
     9241 ccgaccacga gcagtggttc ctggtcaacg catcgccgga cgtgcgcgcc cagctggagg
     9301 cgtcgccggc gctgctgccc gccgcgggca gggcgacacc gctgcaaggg gtgctgctca
     9361 ccgacgccga gctggatcac gcgctgggcc tgttgctgct gcgcgaggcc gaatcgctgg
     9421 aattgcacgc caccgccgcg gtgcacgaga cgctgcgcac ggacaactcc ttgctggcca
     9481 cgttgcaggc ctactgcccg gtgaagtggc gggaggtcgt gcccggcgag gacgtggcgc
     9541 tcggcaacgg cctgagctat cgggcgttcg acgtccccac caccaagcgg tcccgcttcg
     9601 ggcctgatcg aggccccggc agggtcgtgg gctaccgctt caccgacgaa cgctccggac
     9661 gtgccgcggt ctgcctgccc ggagttcagg agatcaccgg ccaggtgcgc gaacagctgc
     9721 gggactgcac cggcctgttc atcgacggga cgtgcttcag cgacgacgaa atgccgcggc
     9781 tcggcctggc gagcaagacc tcccgcgaga tggggcacct gccgatgagc ggtcccggcg
     9841 gcagcctgga gcagctcgcc gagctgccca tcgagcgcaa gatctacgtg cacctgaaca
     9901 acaccaaccc ggtgctgctg gacgactcgc ccgaacggcg cgaggtcgag cggctcgggt
     9961 tcgaaatcgc caccgacggg acagaggtgc agatccgacc gtgacggcac tcgacgaaac
    10021 gcggacttcc gcgggcaccg aggaattcgt ggccgcgttg cgcgcccacg cgcagcgata
    10081 ccaccaccag caccccttcc acgtgcgcat gaacgagggc aggctgagcc gcgagcagat
    10141 ccgcggctgg gtggcgaacc gctactacta ccaggaatgc atcccgatca aggacgcggc
    10201 gatcctgtcg aactgccccg atccggcggt gcggcgccgc tggatccggc ggatcctcga
    10261 tcacgacggg accgcggacg agcccggcgg catcgaggcg tggctgcggc tggccgaggc
    10321 agtgggcctg agccgcgaag aggtccgcga cgagcggcac gtcgtgcccg gggtgcggtt
    10381 cgccgtcgac gcctacgtga ccttcgcccg cacccggccg tggaccgagg cggtcgcttc
    10441 ctcgctgacc gagctgttcg caccggacct gatgagccgc aggctcgccg cgttcgagca
    10501 gcactacttc tgggtcgacc gcgatgggct ggcctacttc cgcaaccgcc tggagcaggc
    10561 cccgcgcgac tccgagcacg gcctgcaggt gaccaccgag cggtgccgct cggccgcgga
    10621 gcaagaacgg gcgctggcgg cgctgtcgtt caagtgcgac gtcctctgga gcatgctcga
    10681 tgccatcgac caagcccacc ccggctgagc ccgcccggct gccggactcg gcccggccgc
    10741 acctgacgac cgggttgcgg ttgaccttcg acgaggtccg cgcgcggcac gtgctgctgg
    10801 gtccggaatc ggtgctggtg ctcaacccga ccggcgcggc catcctgcgg ctctgcgacg
    10861 ggcggcggga catcggcgag ctgatcgccg aactgcaggc gcagttcgca ggtgtcgagc
    10921 ccggcgaggt gcgcgccttc ctcgaccacc tcgccgccaa gcggtgcgtg gaggccgccc
    10981 atgaccgaca tgactcctag cccgttcggc ctgctggccg agctgaccta cgcctgcccg
    11041 ctgcattgcg cgtactgctc gaacccgctc aacctggccg actaccggga cgaactgtcc
    11101 actgcggact ggcagcgcgt gctgcgcgag gcgcgcgatc tcggcgtgct gcagttgcac
    11161 ctctccggcg gggaaccgtt gcagcgccgc gacatcgtcg agatcgtgcg caccggcagc
    11221 gaactcggga tgtacacgaa cctgatcacc agtgcgctcg gactgtcccg caggcgtgcc
    11281 gaagagctgc gcgcgaccgg tctcgaccac gtgcagatca gcgtgcaggc cgacgagccc
    11341 gccacctcgg accggatcgc aggcacccgt tccttcgccc gcaaagccga ggccgcccgc
    11401 atggtcaagg aactggggtg gccgctgacg gtgaacgtgg tgctgcaccg gcagaacctc
    11461 gaccgcatcg ccgaaatcgt ggccctggcc gaggagttgg gcgccgaccg gctcgaactc
    11521 gccaacacgc agtactacgg ctgggcctgg cgcaaccggg acgtattgct gcccagtcgc
    11581 gaccagatcg agcgggccga acaggtcgtg cgatcagagc gggaacgcct gccgcacatg
    11641 gaaatcatcc acgtgctgcc cgactactac agccagtacc ccaaggcgtg catgggcgga
    11701 tgggcgcaac gccagctcac catcgcgccc aacggggacg ccctgccctg cccggcagcg
    11761 caatcgttgc cgctgccgcg ggaaagcgtg cgcgagcgcc cgttggcgcg gatctggcag
    11821 gagtcgccgc tgttcgaggc gttccgcggc acggactgga tgcccgagcc gtgccggagc
    11881 tgttcgcgcc gcgacgtcga cttcggcggc tgccgctgcc aagcgttcca actcaccggc
    11941 gacgccgcgc gcaccgaccc ggtctgccac ctctcgccgg accgcgaact cgtcgaccag
    12001 gcggtacgtg cggccaacgc gagcgaggaa accgtccgcg gcgagctcac cccgcggccg
    12061 catccgcgag accagcgttg acgggctaat cgctgtccag gggaacctca ccgaaggcca
    12121 tcaggctgat gacgaagtaa ccgatgtaga gcgcgagcag aacggccccg tgccagcggc
    12181 gcaaccgccc ggtcgccagg aagatcgccg agaggaccgt catcaccagc agcacgggaa
    12241 ggtgccagga cagcacgttc gcgttgaccg tgatggcccc gcccaccagc agcacgatgc
    12301 cgagcttgcc ggtcaccgag aacacgatgc tgccgatgac gttggcgacg ccgatctccg
    12361 gcgcgcccct gcgtgcgggc tccacggtca ggaagaggtc ctcgagggag agcaccagcg
    12421 tcgcgatcgt gacgccgaag acggtgccgt cgatgccgaa ctcgtcgagg atcccgtcgg
    12481 tgccctgtcc cgcgatgctg gctccgacga cgagaccggc caacgccagc accgcgagcg
    12541 cgagaccggc ccacaggggc cgttgacggg cttgcacgaa gccctggtcg acgcgcaggt
    12601 cgttcgggag ggcgagtccg ccggaaccgg agggccctgc gtcgtccgcc gcatcgtcgc
    12661 tttcggccgc tgcggcggtt ggcgtcgccg ctgcaccggt gcgggtgccg accttctcga
    12721 cctgctcgta gagctcggcg ttgcggaaca ccgggcgtcg cgatgtgtat tcgcgatagc
    12781 cgatccagca cacgaacgcc acgaacagga ccagcagcac gatgcccgtg accgatgtca
    12841 gcgccccggt caaggccagg gcccacagca cgaccggccc tgccacgaaa agcgcgaggt
    12901 aatccttggg aacgtcgacg cggcacggag cgatcagcgc tgccaacgcc agcacgatcc
    12961 ccgtcatcgc gatcgtcgtg ccgatcaccg tgcccagggc cacgtgctcc agttcgtcga
    13021 cgttgagcac gatgccgaat gccagatcgt cgaactcgat cccggtgaac acgaccgcga
    13081 tgaggaacag cgagaccgcc cacctgctgg ccacgccgac caggaacccg atgagcttct
    13141 cggcgctgta gaccagcagt gcgatgccca atgcgaactc gacgaccggg atcacgggaa
    13201 actcctcgcc gagccgacgt cagggagatc cgatcatgct gccccgctgc gcgcgggttt
    13261 gcaacaccgt ttccccggcc ggtcgccggt gcgcactccg gccgagcggc cgaacgacac
    13321 ccggtgcgcc tgtggcgaga tcaccgtccg gacggcgtgc gcgtccggac cctcgagccc
    13381 agcacgacgc tttaccgcac cagccatctc ccataacctg acgatcatga ccgcttgcag
    13441 ctcccgtccg gagcggcggt gaggccatga gcgtcgcgaa cctgcacgaa cggaccttca
    13501 cggtccaacc gcaggcagtg ggtgcgctgc tcgacgcgct cgcggccgag ggagatccca
    13561 cgtggcccgg cgacatctgg cccgccctgc gcctggaccg cccgctcggc atcggggcga
    13621 cgggaggaca cggaccgatc cgctaccacg tggtggccta cgtccccggc cagcgggtgc
    13681 ggttccggtt cgaccggccg cacgggttcg acggtttcca cgagttcatc gtgctgcccg
    13741 accatgacgg cacggtgctc cagcacaaga tcgccatgcg agtgcgtggt cctgcgctct
    13801 tgacgtggcc cctggtcttc ggcccgctgc acgacgctct gctggaggac ctgctcgatc
    13861 gtgcggagga acacctcacc gacggcgtcg ctcgacgcgc ccggtggagc tggtgggtcc
    13921 gagtgctgcg tcgcctgtcg atgccgcggc gcaagacctc ccgggcgcag gcgggcgagt
    13981 ccgcctagtc gcgcgagagt cctcagtgga ccaatcggcg agcgattcgg gggaacctcg
    14041 gccgcgcggc gcggctagca ctgctcgttc agccaggccg cggtcgcctc ggcagcagct
    14101 gtgccgggaa gcaggggtat gccgtgcccg cagtcgagca cgttcaggtg cgcgccaacg
    14161 tggtcggcga gttcgcgcaa cgccgacacg ggcacgagcg gatcccgctc ccccgcgacg
    14221 attcgcaccg ggcaccgcaa cggatcgacg tcgaccggca gccggaaccg gaccgcgtcg
    14281 aggaccgcga ccggggactc gccgaccagt gttcgcgccc acgcccgcgc ggtggcccgg
    14341 cccgcgtcgt cgtcgagatc caggtggtcg aagaacatgc tggtggcggt gctgacgtcc
    14401 ggcggccgcc acaggcggtc cggacgcggc cgcaccggga tcggttcggc accgaagccc
    14461 cgcggcacga cgggagccac caacacgagc gcggccacgt tgccgtgccg gcacgcccag
    14521 tcgaggcagg cgaatccgcc catgctgtgt ccaatgagga ccgccgggcg ccgcaaccga
    14581 tcgagcaccc tggacagttc gccgccggcg tcggcaacac tgcgcaagga acgcccgagc
    14641 gcatcggcca ccggcgccga accgaaccgg ccgaaccagt tcggcgcgta cgtgcgccat
    14701 cccgccgctg ccagcaccga gctccattgc cgccagcacc aggcgccgtg gcatccgccg
    14761 tgcagcagca cgacgggcgg ccgatcatcc gccggctcgg ggtccgggcc tgcgacctcg
    14821 acaacgacac cgttccaccg cacgcgctcg gcgaacacca caccaccctc cgttcctccg
    14881 ccccagccgg cgagatcgag cacggcggtc cgacgttagc gggcgaggaa gggaagttgc
    14941 ggtgatcgcg cgcattccac tccgatgatg tagcgatgga agagctgctt ccgctccgcg
    15001 cccgtccgac tgccgagctc cacgggcaat atttcccaag aacccgagcg ctttgaccat
    15061 tattcgtcca cattggacat cttgtttcct gccgccggaa gcaacgcctt ggtccgtccg
    15121 gaccaccacc cccgctgcaa ttcggcgaag accgcccgag ccattcattt ccgcctcaat
    15181 tgaccgatca aatcgaatat tgaccggcat ttccagccgg gctacgttca gctcgtggcg
    15241 atcccggcgt acttgcgcat ccgcaccgaa ctggagcagc agatccagtc cggtgcgctg
    15301 gcgccgggta cgcggctgcc cacggaggcc gaactccagc agcggtactc ggtcggccgc
    15361 gccaccgcgc agcgggtgct gaccgagctg tcccgggccg gactggtgga acgccaccgg
    15421 cggcgcggca ccttcgtcgc cgacggtgca cggcaggaga acctgctgcg catggtgcat
    15481 ccggcgctgc acggcccgga gattccggga ccgcacgcgg tggattcggc catggtgatc
    15541 cccgccgagg acgccgacgt cgcccttccc ggcatcaccg gggacgcgcc ggtgaaccaa
    15601 ttgcggcggc tgaagttcga cgtcgagcac aacccgatcg cagtcgagct cgccgccgtc
    15661 ccgttctcgc tggcaccacg cctgttcgac gagaacctgg aacacctcac ggtgcacgac
    15721 tacttcgccc gcaaccggat tccggtggcg aagtcgcgcg tgtacgtcga cccgattccg
    15781 ctcgatgcgg cgaccgcggc ccgcttcggc accgagccgg gccgggccgt gatccggttg
    15841 cgccggttga cctggctgac cggcggtggg ctggccgagg ccatgtggca catcatccgg
    15901 cccgacctgg tcgagttctt cgtcgagcaa tccgtgctgg ccacctgata cgacttcgcg
    15961 tccgcccggg gatctgcgct tcccggccga ttcctgctgc cgctgctccc gcagcacggc
    16021 ttttccgctc gcactcgcag aatgggagcc accaatgacc tcaccacgcg tcgcggtggt
    16081 cggcaccggc gtcatcggcg ccatgacggc atggcgcctg gcccggcgcg gagccgacgt
    16141 gatcgcactg gacgcccttt ccccgggaca cgaccgcgga gcctcggccg gcgagtcccg
    16201 catcttccgc acgctctaca aggagggatc cggttacgtg ccgctgctgc agcgatccgg
    16261 cgcgctgtgg cgcgagctgg aactgagcac cggcacccgg ctgctgacga tgtgcggagg
    16321 cctcaccatc ggtccgcgcg agcacgccga tgtccgagcc gtgcgccgct gcgccgagga
    16381 gcacgacctc gaccacgagg tcctggacac cgcggcggct cggcagcgct tcgcgcagca
    16441 ccggatcgac gacgacgaga tcatggtgtt cgatccggcg gcgggcgtgc tgcggcccga
    16501 acccgcggtg caagcagcgc tgcacgcggc cgggctcgcg ggcgcgtcga tcctgcccta
    16561 ccaccgggtc gacgatgtcg ccgaaaccgc gcggggatgg cgaatcacca gcggtgccac
    16621 gcacttcgac gtcgaccacg tcgtgttcgc cccgggcccg tgggcgcggc agctggaccc
    16681 gctgagcacg cttcccgtcg agatccggtt gatcaccgcg tactggttcg cgacccgcga
    16741 caccgccgcg caccggccgg accggttgcc gatcgcgatc cgccgccacc gggacgccgg
    16801 gttctcctgc ttcccggtgc tggacggggt cggcatcaag atcatcccgc atcacctcgg
    16861 atggccggtc ctgcacgacc cggccgcgct gccccgttcg gccgagccgg agtacgcccg
    16921 cgcggcttcg gaagccgccc ggcggctgct gcccggggtc gtgccgcacc cggtgcggat
    16981 cggcacctac gccgagggct tcacgccgga cgagcacgcc ctgctgggcc cgctacccgg
    17041 gcaccgcaac gccaccgtca tgaccggctt ctccgggcac ggcttcaagc tcgccccggt
    17101 cttcggcgag ctcggcgccg agctggcgct cggggaaccc gccagccacg acatcaccgc
    17161 gctggacccc ggccgccgcg cggactgaga accgtccaca caggacccct ggaggcaacc
    17221 gtgcccaccg gttccaccgc ccaaatcgcc ggagtcgtcc tcgccagcct gctggtgatc
    17281 ggtttcggag tggccatgtc ggtccatttc ggacgcaagg cgaagaccgc gcaggactgg
    17341 ctgtcggccg gcgagtcgct gccgctggtc gtagtgatca tcacgcagtt cgcgaccgcg
    17401 accggcggcg gggtgctcat cgcgcacgtc ggcatcggct accgctcggg ctggtcggtc
    17461 ttcgcctacg agggctgcgt gctggtcggc ttcctcgggt tgatgctgat cgccaaatgg
    17521 ctgcggcagc agcggttcac caccgttccg gacgtcgtga cccggctgtt cggcaggcat
    17581 cggatggtca ccgccatcgc cgcgctggcc gccctggtgg tgccgttcgg ctggctggcg
    17641 acccagttcg tggccttcgc ccagcttttc ggccggctga ccgggatgcc ggacgccgcg
    17701 ctgatcgtcg tgatcatgct ggcatcgctg ctgttcgtgc tgccgggcgg aatgacgtcg
    17761 gtggcctgga cggacttcgt gttcggcatc ttgatgatcg ttctgtcgct cggcgtcgcg
    17821 gcctacgcgg tcgacctggc aggcggctgg cggcagatca ccgagaccgt gccgcggcag
    17881 ctgtggggct ggggcgggtt caccgcggcc ggcggggagc agctctggct ctggatcgcc
    17941 gcgatcgtgc cgggcacgct gaccaaccag ctctactacc agcgcgtgtt cgccaccaag
    18001 aaggtctccg acgcccggcg cgggctcgcg ctgtccgggc tgacgatgct catcggcggc
    18061 gtctacgccg gatgcatcgg gctcgcggtg cactcgctga acccgggtct gaccaacgag
    18121 gaggacgcgg ccggatggct gctgacccgg ctgccgagct ggctggtggt ggtcttcggc
    18181 gcgttcctgg tctcgacgat cgtctcgacc acgggcgccg ccctgcaatc cgtggtcgcc
    18241 aacctgacca gggacgtcta ccacaacatc gtgggcggcg agcacgacga acgccggacc
    18301 gtgcggctgt cgcggacgat cacggtcgcg gtatccctgt tggccgcggt gctggcgatc
    18361 ctgttcccca aggcgctgac ctggctggtg gccacctacg cctactcggc cgcggcgctg
    18421 gccgcgccca tcttcctcgg ctacctgctg caccggcgac gtcggctgac accggcgacc
    18481 gcgatcgcca gcatgatcgc cggggtcgcg ggctgcgcgg ccgcccagct ggcggacacg
    18541 accgttccgt acgcggtgta cgggatcgcc gcctcggccg cggtgctgct ggtattggcg
    18601 atgctcgcac ccgccgaccg cgaccagacc ccgcacgcgg gagtgaggag ctgagcatgc
    18661 ggatcgccgt catcggactc ggagtgctgg gcgccagtgc cgcccgttcg ctgagcctcg
    18721 ccggcgccga ggtgaccgtg ttcgaacggt ccggcgccct cgccggaacc tccggaacct
    18781 cgttcgcctg gaccaactcg cacaacaaga acccgcgcgc ttaccacgat ctcaacgtcg
    18841 ccgggatggc cgagcacgag gcgctcgcgg cggatccggg accgcaccgg cgctggttcg
    18901 cgcggaccgg caacctggag tgggccgccg acgaggccgg aaccgagcgg ctcgccgctt
    18961 cggtcgccga gctcgcggcc cgcgactacc cggtcggctg gatcactccc ggacgtgccc
    19021 gcgaactggt cccggacctg cgggttcccg ccgggatcga ggacatcgcc tactacccga
    19081 ccgaaggtca cgtcgtaccg gcactcctgc tggcgcggtt gtggggccag gcaagggatc
    19141 tcggggcgcg gttgcgctgt cctgccgagg tcctcggtct gtccgaagtg gagcgaggag
    19201 tgcggatcga gctggccgac ggcaccgccg aagccgacgc ggtggtgctc gcggcggggc
    19261 ggtggaccga ggagctgagc gccgcagcgg gctgccggat accgatggcc gcaccggacg
    19321 ccgcgggctc ggcgaccgtc ggtctgctcg gctacaccag ccccctgccg gtgcggatgg
    19381 accgggtgct caccacgccg aagctcaacg tccgcccgga cggcggcggc cgactggtcg
    19441 tccagggcct ggatctcgac gccgacgcgg atccggccgc gcccccggcg gtgaacggcc
    19501 ggcacgcgca ggagctgcgc ggcaggctca ccgaactgct ggggcaagcc gccgggttgg
    19561 aatccttgcg ggtgggccag cgagccatgc ccgccgacgg gctcaccgtc gccggattcc
    19621 tcggcggcag cggacggatc tacgcgatgg ccacccacag cggcatcacg ctcgggccac
    19681 tgctcggcaa gctcgcggca caagagatca ccaccggcga ccccgcggag gcgctggcgc
    19741 cgttccggcc ggaccgcctg atcggcaggt ccggcctacc gccgctgaca ccggcccgct
    19801 tcgccggaca gcagtgagcc ccggtgaaac gttcggcggt gaaggcgagc agggcggtca
    19861 cgcggtccgc tccgggtgcg gaacgcctcg gaaccgcacc gcgcggccga cctgctcatg
    19921 tcttcgcgga ggctccgagg cgttctccca gcgctagcgc gcggcgtcgt actcctcgtc
    19981 ggtgacgtgc ctgccccagg tgacgggatt gccggactcg tcgttctgct gcatggcgac
    20041 gtgcaccatg aaccggttcg gggcagcgcc gtgccagtgg ttctcccccg gctcgaagaa
    20101 cacgcggtcg ccgggatgca ccgtctcgac cgggccgcct tcgcgctggc acagtcccac
    20161 gccctcggtg acgaagatcg tctggccgtg cgggtgggta tgccacgcgg tgcgcgctcc
    20221 cggggtgaaa tgcacgttgg cggcgccgaa cgcggagccg gcggccggtg cggcgacggc
    20281 gtcgatgtag acatcgccgg tgaaccagtc cgcgggcccc tgctgggtgt ccatgctgct
    20341 gcttcgggtg atctgcacga ggtgctcgct ttcgttgtct gctggtgctc gcagggcata
    20401 ccggttccgg ccggacgggc tacgtgctct gggcgccgtc gacgaccagt gcgtgacccg
    20461 agcggccgcc gacccgggaa ccgctcgtac cgagccacgc ccgtcagccg gttccacgat
    20521 gtccgctttc cacccaaccc cgcacgaggc gagcgtggga ggaaccgttc aacggggtac
    20581 tgccagcacc ccgctgacca gaacctgacc gcgccgaccc gccaggttcc ttcgccgccg
    20641 accgtgcgcg cgcacgtcct agtccgcgcg ggttcctgcg gagtcgggtc tcgcgatcaa
    20701 ggtttcgatc atgtgcgtgc gggccttctc gattcccgcg aggacgaccg cgcggatctc
    20761 gtcggcggag tcggtgcgaa tgatgtccac gagccgctgg tggttggtgg cggtgtacgg
    20821 gtggccgagc gcgccctgca ggttcaggaa gcgctcgatc tcttcgtgca gcgcgttgat
    20881 ggtctgcgtc atcaggggaa tgcgccccag ttccgcgatg cgcacgtgga acagccggtt
    20941 cgcttcgtgc cgcgcggccg gttcgtccgc tgcgcggacg gtcgagtcgc tgagttcttc
    21001 gagcgcgtcc agctcggctg cggtcgatcg ctgggacgcg agcacggccg cctcgggctc
    21061 caggagcgtg cgcatgtggt aggtgtcctg cagctcgccg atgtcgacgg acttcacgaa
    21121 ggtgccgcgc cggggcacca cgaccacgag cccttcgcgg cgcagtgcgt tcatcgcctc
    21181 gcggatcggg gtgcggctca tcccgtactg ctcggcgagc gggccgtcca tgatgacctc
    21241 gccgggccgg agcctgcacc gcaggatgtc ccgtttcagc gacgcgtacg cgcgttcgga
    21301 catcgaggct tgccgactca cacctaccgc tcctactgac tccccgcccg atcaagtcgg
    21361 gttgacgcac ctcgcgagcc gactctagca tccgccgtga aatatcacgg tgtacatcac
    21421 agggatccac aacgcggtgg tgctcccccg gccggcgctg tggcggtggt tgccctggcc
    21481 gatcagggct tggagagatg atgcgagtac ccggcgatgt gcgatccggc gtctgcacca
    21541 accgcctgtt ccgggcgctg agcgcgctcg aacgcgcggg caacaagctc ccgcacccgt
    21601 tctggctgtt cgtcatcctg tccctggtcc tgggtgcggc gagcgcagca ctgtccatga
    21661 tggacgttcg ggtcacgctg ccttcgaccg gcgagacggc cgcggtgcgc aacctcttct
    21721 ccgtgcacgg cgcgaaattc gccatcgagt cggcgttgac caactacgcg gagttcccgc
    21781 cgctggcgac catcgtcgtg gtgctgctcg gggtgagcgt cgccgaacgc agcgggctgc
    21841 tcaccgcgct gctgcaaggc accgtgcgcc gattaccggt gggatggctg accttcgcga
    21901 tcgcgctgtg ctcgatgatc gcccacgtga tgagcgattc ggcgtacctg atcatgattc
    21961 cgctgggtgc gctcgccttc cggaccgccg gacgcagccc ggtgctcggg ctgatggtcg
    22021 cgtatgcggc aaccgcggtc ggcttcaact ccagcccgct ggtcaccccg caggacgcga
    22081 t
//
