LOCUS       NZ_JADDUE010000004     23288 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Saccharopolyspora sp. HNM0986
            NODE_4_length_512363_cov_75.780038_cov_75.780038, whole genome
            shotgun sequence.
ACCESSION   NZ_JADDUE010000004
VERSION     NZ_JADDUE010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Saccharopolyspora sp. HNM0986
  ORGANISM  Saccharopolyspora sp. HNM0986
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharopolyspora.
REFERENCE   1  (bases 1 to 512363)
  AUTHORS   Li,F.
  TITLE     Diversity and distribution of actinomycetes associated with coral in
            the coast of Hainan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 512363)
  AUTHORS   Li,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-OCT-2020) chool of Life and Pharmaceutical Sciences,
            Hainan University, 58 Renmin Avenue, Meilan District, Haikou, Hainan
            570208, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 232.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016526145.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 02:15:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,899
            CDSs (total)                      :: 5,838
            Genes (coding)                    :: 5,784
            CDSs (with protein)               :: 5,784
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 7 of 54
            Pseudo Genes (incomplete)         :: 49 of 54
            Pseudo Genes (internal stop)      :: 0 of 54
            Pseudo Genes (multiple problems)  :: 2 of 54
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:09:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 358537
            Orig. end                         :: 381825
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADDUE010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23288
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="2"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..23288
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23288
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13288](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13288
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(213..227)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    complement(908..927)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.81"
                     /tool="antismash"
     gene            970..1941
                     /locus_tag="INP57_RS12045"
                     /old_locus_tag="INP57_12045"
     CDS             970..1941
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104532.1"
                     /locus_tag="INP57_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12045"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_200070227.1"
                     /transl_table=11
                     /translation="MTTQEEPEHATSASDSVTVRAAGAVLWRPDDDGTPRIALVHRPRY
                     DDWTLPKGKLDPGETPAHAVAREVLEETGFGCVLSGELAQIRYSVPAPGGYTGKRVDYF
                     AARAGQGLFAVNEEVDELRWLSTAAARELLTYPHDGHVLDAFDALPLESRTLLLVRHAK
                     AGKRSEFTGDDTQRPLSAAGLRQRDALHTLLPLFGPQRVYSAPRVRCTQTVQPVADDLG
                     IAVADEPLLTEEQYQADPAAAVRRLLRIAGGSGTSVVCSQGGVIPDLVGRLTESAGLRP
                     DEVLSSKGSVWTLRFCPDANSGNGSGPLLRLVAADYLPDPRG"
     gene            complement(2365..3186)
                     /locus_tag="INP57_RS12050"
                     /old_locus_tag="INP57_12050"
     CDS             complement(2365..3186)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0030527 - structural constituent of
                     chromatin [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944412.1"
                     /locus_tag="INP57_RS12050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12050"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_200070228.1"
                     /transl_table=11
                     /translation="MNKAQLIEALAERLGDKKTASQAVEGVVDLIVRNVNKGEKVNITG
                     FGVFEKRARAARTARNPRTGEAVKVKKTNVPAFRAGTQFKEVVGGSRKLPRATATKSAG
                     TRSTATKTAGTGRSTAKSTGTAAKSTGTAGKATATKTAGSRSTAAKSATTTKAAPKKAA
                     TTRSSAKTGATTKATTSKAATTGKSTASKAATTGKAATTSKATTSKATTSKAAPKSTTG
                     KASTAKASTGSKSTGTKSATKSTKSTASAAKTSAAKTSTAKTSTARKTTKK"
     misc_feature    3144..3158
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(3417..4019)
                     /gene="leuD"
                     /locus_tag="INP57_RS12055"
                     /old_locus_tag="INP57_12055"
     CDS             complement(3417..4019)
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944411.1"
                     /locus_tag="INP57_RS12055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12055"
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="WP_200070229.1"
                     /transl_table=11
                     /translation="MEPFTTHTGVGVPLRRSNVDTDQIIPAVYLKRVARTGFEDALFAA
                     WRGDETFVLNNEAFRNGSVLVAGPDFGTGSSREHAVWALKDYGFRVVISSRFADIFRGN
                     AGKQGLLAAECEQSDVELLWKLLENEPGTEVTVDLQERTVQAKDLTVGFSLDDYTRWRL
                     LEGLDDIGLTMRHAETIDTYEQHRPAFKPATLPAREG"
     gene            complement(4047..5450)
                     /gene="leuC"
                     /locus_tag="INP57_RS12060"
                     /old_locus_tag="INP57_12060"
     CDS             complement(4047..5450)
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944410.1"
                     /locus_tag="INP57_RS12060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12060"
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="WP_200070230.1"
                     /transl_table=11
                     /translation="MGNTLAEKVWDGHIVRRGEGYEPDLLYIDLHLVHEVTSPQAFEGL
                     RLADRPVRRPDLTIATEDHNVPTTGTELPIADPVSRTQVDTLRRNCEEFGVRLHPMGDA
                     EQGIVHVVGPQLGLTQPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPLRP
                     FKTMAINVEGTLRPGVTSKDIILAVIAKIGTGGGQGYVLEYRGEAIRQLSMEARMTICN
                     MSIEAGARAGMIAPDETTFEYLRGRPHAPQGADWDAAVAYWKTLRTDEDAEFDAEVTLD
                     ADELTPFVTWGTNPGQGLPLGERIPDPEAIAEDSERYAVEKALAYMGLQGGTPLREVVV
                     DTVFLGSCTNGRIEDLRSAAAILDGRKVSSDVRMMVVPGSMKVRQQAESEGLNEVFTAA
                     GAEWRSAGCSMCLGMNPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRG
                     TLSSPEDLD"
     gene            5569..6270
                     /locus_tag="INP57_RS12065"
                     /old_locus_tag="INP57_12065"
     CDS             5569..6270
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005158149.1"
                     /locus_tag="INP57_RS12065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12065"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_200070231.1"
                     /transl_table=11
                     /translation="MGQHSGIGVLDKAVAVLQAVAEEPCGLTELCSRTGLPRATAHRLA
                     VGLEVHRMLRRGSDGRWRPGASLAELAGGAVDPLLEASSTVLPKLREVTGESVQLYRRD
                     GLQRLCIASAEPPSGLRDTVPVGSTVSMMAGSGAKVLAAWADPATQRAVLAEAVFGERT
                     LLEVRRRGWAQSVAERESGVASVSAPVRDSQGTVVAAISVSGPIDRMGRRPGARWAADL
                     LAAADALQNRI"
     gene            complement(6518..7294)
                     /locus_tag="INP57_RS12070"
                     /old_locus_tag="INP57_12070"
     CDS             complement(6518..7294)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="INP57_RS12070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="INP57_12070"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_200070232.1"
                     /transl_table=11
                     /translation="MAESTGTNEPGAWESYWQLAGTSPDLPVPWHFGTAEDMAPYLPML
                     LAGFDSRLPLVDAGCGNGGLTEHFAEHFETVLGTDVAAAALEKAHTGNGNTWIGRTRIG
                     RTGNGHTGVRYEQLDSTDLAAVRALHERIGDANVHLRGVLHAMAAEQWPNALAGLAVLT
                     GQRGRVFDVELSERFTESLAELAECFGEWPEAIREAATTGLWPAELPAQGLTGLYRRHG
                     WLVLEAGELALSSRVPLPDGTFLHLPFEYALVRRHA"
     misc_feature    7374..7390
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(7471..7487)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    complement(7474..7487)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            7612..8364
                     /locus_tag="INP57_RS12075"
                     /old_locus_tag="INP57_12075"
     CDS             7612..8364
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017534.5"
                     /locus_tag="INP57_RS12075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12075"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_200070233.1"
                     /transl_table=11
                     /translation="MAEQSGAPEFVKENVDFEACYQGQRFLAGTDLTFPVAPWDIGEPQ
                     PALVELADRTAFSGDVLDAGCGLGENAIFLAGRGYRVTAFDCSPTALDRARARARECAA
                     QVEFVQADATRLGELSGRRFGTVVDSALYHCLGAQQQHRYAAALHEVTEPGARLHLLCW
                     AVAGEDAAVRHPMGVGEQSIRATLDARWEVLEVRTAQISTALIRDALTEADIALFARKG
                     VGIDPGRAAVDDRGRISAPAWFVSAVRR"
     gene            8516..9964
                     /locus_tag="INP57_RS12080"
                     /old_locus_tag="INP57_12080"
     CDS             8516..9964
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013739.5"
                     /locus_tag="INP57_RS12080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12080"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_200070234.1"
                     /transl_table=11
                     /translation="MAAEPPAVAILGAGIAGLVAAHELERLGHSVIVLEGSGRIGGRVF
                     THRFGSADNAPYADLGAMRIPTGHALTMRYVDELGLTPALRPFRTILSDPNNYLATGRG
                     FVRVRDAAGPVVEDLRCAVPVDSFRRDTVLFCAWLAALARAVGPRALRTGLAAEITPML
                     RAADRVDLSSYVHGPADRFDLVGAFDTHPQLREACGVRLAGFIDDLLLETGTRLRYLAG
                     GMGRITDRLAARLRGPVLLDREVVSLHVRGDQVLVGLRHRGVDVLSRYPVAVCTLPFSV
                     LRELQLAGLDDDKREVIRSVEYAAATKIALHCREPFWKRAAVSGGASATGGRLRQTYYL
                     PQDGDPALGAVLLGSYAIAEDAAPLGRLPADRRHAASLEELAGLHPELKAPGAVLGAAS
                     ISWGDHRWSKGCAAHRWRWGKDAAAARAEGMRAARPQGGLFFAGEHCSSTPAWINGAIE
                     AALAVTGAVDAALRTGAADRAQRS"
     gene            10001..13288
                     /locus_tag="INP57_RS30315"
                     /old_locus_tag="INP57_12085"
     CDS             10001..13288
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024306.5"
                     /locus_tag="INP57_RS30315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12085"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_200070235.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1311.6,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIFDLPRLHFAGTAITRLPTGPRSGHYDLAANEALTADGTPFPR
                     DRPAAEYHEHLDGLGERFEPDGRLRPDGRFGTAKGWNFGGNGHFWLDARITGWERVPGA
                     AGAQDPVLGRAVDLWGHFNEHLATTHNRARVFDVDPASDWTTTVLAGQFCFGRQGRSHD
                     TGYMAVGAVDGPQPPRWQNSQHVHGVGEHPLESWFRRSVVHQFAVDADGLEWLPEAEIS
                     EAVRLLRAAAGPGGLVVRYALSNMAAPRDNDTPNVWQVRGTIAARDPAEERTCPAGRLL
                     TAREPRRRGEPAPLHNAAVQVTGEHTTFDLITAVPALGRSPEPGPDGVHRLGPRLDLGD
                     LQLRTRGSGQLVARLPSSAYRADTERTGGLVTVATEPGCAAAEDEPLVLVREGQESAVL
                     LAEEESVVRIDDSCLFLDPAEGDSTEGDSTERDGSAGDGTARVPVRTYHLGRPAPLNGL
                     RVVQFFNPRALPRDPRAQAADARCGAVQIVQVRPDEGAADWAESCTLDTDEQGRAVLAV
                     RCATAGATRLLLLPEGQLPPCDPDEPGSAARAYDNDDRTGYWPAVGCADVRVLPDTRHL
                     DEIPRAEVTHDLLYREVFAPYELLYSFMADEVFSLAEQSKVGTYARLIWLMSDPRHRDK
                     TFYMPPTRDLTRPQGRLLLAHLRRQQAPAPPELVARRDRPGAITTRGQLRDALREAASV
                     ELAGMLQYLYAAWSIPTHEAGQQLVRRGEWTAEQLRLACGDGTETLRNGMRGELLSVAR
                     EEMVHFLVINNIITAMGLPFHLPDIDFGRVNHRLQVPLDLALEGFGLGSVQRFIALEQP
                     HSLTREIAGDVAPDAAGKAYPYQSLSDLYAAIREGIGAVPDLFLVQRGRGGGEHHLFMR
                     RSLNDVHPDYQLEVDDVPSALFAIDFVTEHGEGNVLPGPADEDSHYDTFLRMSDLLMAH
                     RVEAPGQRCPPWTPAYPVLRNPTLHAGDGAREPVTAPEARSAMVLFNRSYFLMHQLMLQ
                     HFHGAADASLRRSRLMNAAIDVMTGMLRPIAEHLVTLPSGRPGRTAGPSFELEEEPGFL
                     ARPDVALRSLGGRFDHLARQAAEQPGLPARVAELMRSYAAEFRGSAP"
     misc_feature    10646..10648
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13380..14129)
                     /locus_tag="INP57_RS12090"
                     /old_locus_tag="INP57_12090"
     CDS             complement(13380..14129)
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (51-149). E-value: 3.8e-13. Score:
                     40.2. Matches aSDomain: nrpspksdomains_INP57_RS12090_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013382.5"
                     /locus_tag="INP57_RS12090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12090"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_200070236.1"
                     /transl_table=11
                     /translation="MESSGKESIAARSAEVGALFDDVAEHFDRMATRMIDAEGPFRTWL
                     DAQLPGGDRALDVGCGTGRHCPLLAERYAQVLGVDLSEALIHIARRTRPAANIRYEARS
                     AYDVEPAADGVFDVVFAFSAVFHMRPYEQILPHLRSLVAPGGRLVVLEPQRTDLHARKG
                     RDADWHIPVAFQNAEAVYRATADAGAATDALNLFLHPSWHKLGELNTLPSSQEFRDAYS
                     GWLPGAQFFDGVAVAMAAAVWQAPDPN"
     aSDomain        complement(13683..13976)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_INP57_RS12090_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.80E-13"
                     /label="INP57_RS12090_oMT.1"
                     /locus_tag="INP57_RS12090"
                     /protein_end="149"
                     /protein_start="51"
                     /score="40.2"
                     /tool="antismash"
                     /translation="GDRALDVGCGTGRHCPLLAERYAQVLGVDLSEALIHIARRTRPAA
                     NIRYEARSAYDVEPAADGVFDVVFAFSAVFHMRPYEQILPHLRSLVAPGGRLV"
     misc_feature    14192..14206
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     tRNA            complement(14716..14791)
                     /anticodon=(pos:complement(373292..373294),aa:Glu,seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="INP57_RS12095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="INP57_12095"
                     /product="tRNA-Glu"
     gene            complement(14716..14791)
                     /locus_tag="INP57_RS12095"
                     /old_locus_tag="INP57_12095"
     misc_feature    15005..15019
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.9"
                     /tool="antismash"
     tRNA            complement(15322..15394)
                     /anticodon=(pos:complement(373895..373897),aa:Glu,seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="INP57_RS12100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="INP57_12100"
                     /product="tRNA-Glu"
     gene            complement(15322..15394)
                     /locus_tag="INP57_RS12100"
                     /old_locus_tag="INP57_12100"
     misc_feature    15420..15433
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     tRNA            complement(15457..15528)
                     /anticodon=(pos:complement(374030..374032),aa:Gln,seq:ctg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="INP57_RS12105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="INP57_12105"
                     /product="tRNA-Gln"
     gene            complement(15457..15528)
                     /locus_tag="INP57_RS12105"
                     /old_locus_tag="INP57_12105"
     misc_feature    15496..15516
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.1"
                     /tool="antismash"
     misc_feature    15607..15620
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.4"
                     /tool="antismash"
     misc_feature    15607..15623
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.46"
                     /tool="antismash"
     gene            complement(15721..16500)
                     /locus_tag="INP57_RS12110"
                     /old_locus_tag="INP57_12110"
     CDS             complement(15721..16500)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644215.1"
                     /locus_tag="INP57_RS12110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12110"
                     /product="HAD family hydrolase"
                     /protein_id="WP_295141012.1"
                     /sec_met_domain="HAD_2 (E-value: 2.5e-22, bitscore: 74.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPEPPNAPPPGPIKAVCLDIDDTLLDNATSSRMGLRALIGND
                     AAWPVWRSTTEQHYARFVAGEYDFATMCRERTRDFFAAFGEQLGDTEVAAREDYRMAAM
                     QRAWQLFDDARPCLDWMRASGLRLAVITNADSAYQRKKISDTGLAGTFDDLVISGELGV
                     AKPDPQIFHAACTAVGAEPHETVHVGDRLDTDALGAANAGMHGVWLNRNGTEHAPPDGV
                     SMITSLAELPELLVCDLPGIPEAAAPQDETRHERALA"
     gene            complement(16623..18137)
                     /gene="gltX"
                     /locus_tag="INP57_RS12115"
                     /old_locus_tag="INP57_12115"
     CDS             complement(16623..18137)
                     /EC_number="6.1.1.17"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874967.1"
                     /locus_tag="INP57_RS12115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12115"
                     /product="glutamate--tRNA ligase"
                     /protein_id="WP_200070237.1"
                     /transl_table=11
                     /translation="MSTSEVTATPHSTVRARFCPSPTGTPHVGLIRTALFNWAFARHHE
                     GTLVFRIEDTDASRDSQESYDALLDALRWLGLDWDEGPGAGGEHGPYRQSERKDIYADI
                     AQRLLAAGELYEAFSSPEEVEARHKAAGRDPKLGYDNHDRHLTEDQKAEFRAEGRNPVL
                     RLKMPEHDLAFTDLVRGEITFPAGSVPDPVLVRGNGEPLYTLTNPVDDALMRITHVLRG
                     EDLLSSTPRQIALYESLRRIGVTDFTPEFGHLPFVMGEGNKKLSKRDPQSDLFHHRARG
                     FLPEGLLNYLALLGWSIADDRDVFTLDEMVEAFDIGRVSANPARFDQKKADAINSAHLR
                     ALAPDDFVQRVVPYLIDGGVLPAEPTGEQLETVRAAAPLVQERLIVLSDAVNMMGFLFA
                     GEDFEPDEASAQKALGEDARPVLEASIGALEQLPEWDTDSIEAALRAAVVDGLGIKPRK
                     AFAPVRVAVTGRTVSPPLYESMELLGREVSLSRLHRALDGNTAEMR"
     gene            18247..19485
                     /locus_tag="INP57_RS12120"
                     /old_locus_tag="INP57_12120"
     CDS             18247..19485
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010231951.1"
                     /locus_tag="INP57_RS12120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12120"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_200070238.1"
                     /transl_table=11
                     /translation="MTRTERTTCCIVGGGPAGMVLGLLLARSGVQVTVLEKHGDFLRDF
                     RGDTVHPTTLQLLDDLGLAERFAELPHRRVDRVRLPVGQREDQFLTIADFTRLPIKYNY
                     IALVPQWDLLDLLADEAKQQPGFDLRMNTEVTGLVREGGRVNGVRYRESDGSTGELRAT
                     ITVACDGRDSLVRQLPELGLRDFATPMDVQWFKIPRRADDPAGLLGLIADRTFQALIDR
                     GDYYQAASIIGKGTDAERRARPVAEFNERLRRFLPWLDDGRDLVRDWDDVRLLSVKLDR
                     LRKWHVPGLLCIGDAAHAMSPVGGIGINLAVQDGVAAARYLATPLREGRLRRKHVAAIQ
                     RRRWPTTVLIQQLQRVLHRNAVAPALRGEVDFYKSLPAPVRLVTNAPALRVVPPYVLAY
                     GALRERPPQEALR"
     gene            complement(19640..20422)
                     /locus_tag="INP57_RS12125"
                     /old_locus_tag="INP57_12125"
     CDS             complement(19640..20422)
                     /EC_number="3.7.-.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012796388.1"
                     /locus_tag="INP57_RS12125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12125"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_200070239.1"
                     /transl_table=11
                     /translation="MRLARVAHSDGVSFVALEPDPSAPQEKVLAIEIDQHPFGEPTFTG
                     RKWPMADVRLLGPILPSKVICVGKNYAEHAREMGGEVPQNPIIFMKPSTSVTGPNAAIK
                     LPPNSERVDYEGELAAVVGQPCRDVPEARGADVLLGYTVANDVTARDQQQADGQWTRAK
                     GYDTFCPLGPWIDTELDPGDLGLRTELDGELKQESRTSLLLHDVPALVSYISRIMTLLP
                     GDVILTGTPAGVGPMQAGQQVSVSIDGLGTLTNPVQDR"
     gene            complement(20570..22213)
                     /gene="cimA"
                     /locus_tag="INP57_RS12130"
                     /old_locus_tag="INP57_12130"
     CDS             complement(20570..22213)
                     /EC_number="2.3.3.21"
                     /GO_function="GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cimA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012796387.1"
                     /locus_tag="INP57_RS12130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="INP57_12130"
                     /product="citramalate synthase"
                     /protein_id="WP_200070240.1"
                     /sec_met_domain="HMGL-like (E-value: 5.2e-41, bitscore:
                     135.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTTPAGTPLGDDFHVYDTTLRDGAQREGISYSVPDKIAVAKLL
                     DSLGVGFIEGGWPGALPKDTEFFARAAAGELRLDHAALVAFGSTRRAGAQAHEDPQVRA
                     LVDSQAPVVTLVAKSDRRHVERALRTTVEENCAMVADTVRYLVGEGRRVFVDAEHFFDG
                     YAHDPDASLRVLEAAMTAGADVSVLCDTNGGQLPMQLASTVEEIVARTGFRVGIHCQDD
                     TSCAVANSIAAVQAGATHVQCTANGYGERAGNADLFAVLGNLATKLDMPVLPEGKLTEL
                     TTVSHALSEIANLAPDTHQPYVGSSAFAHKAGLHASAIKVDPELYNHLDPDVVGNRMRV
                     LVTEMAGRASLELKGAELGLDLSDSPEAVSGAVRKVKELEARGWSFEGSDASLELLLRR
                     EMDAAGEAEAGAVDAPFELESYRVLLDHRPDGTVVSEATVKIHVDGERVIATAEGNGPV
                     NALDAALRKALVPHLPWVDSVELVDYKVRILTDAAGTDAVTRVLVESRDDQDEWTTVGV
                     HGNIVEASWLALCDALAYKALRRTVLSGAD"
ORIGIN
        1 cgcggatccg cacgtgctgg cgatcaagca gacgctctac cgcacctccg gcgactcgcc
       61 gatcgtgaac gcgctgatcg acgcggccga ggcgggcaag caggtggtcg cgctggtgga
      121 gctcaaggcc cgcttcgacg agcaggccaa catccagtgg gcgcgcaccc tggaacgttc
      181 cggggtgcac gtggtctacg gcctggtcgg gctgaaaacg cactgcaaga ccgcgctggt
      241 ggtgcggcag gaaggttcga cgatccgccg ctactgccac ctgggcaccg gcaactacaa
      301 cccgaagacc gcgcgcacct acgaggacct ggggctgctg accgcggagc cggcggtcgg
      361 cgcggacctg acggacctgt tcaacgtgct caccggctac gcccggcacg gcacctaccg
      421 ccgcgtcctg gtgtccccgc agggcatccg ctccgggatc gtggaacgca tcgaggccga
      481 ggccgaacgc gcccgcgccg gattgccctg cggcatccgg atgaaggtca attcgctggt
      541 cgacgagcag atcatcgaca cgctctaccg cgcttcgctg gcgggcgtgc cgatccggat
      601 cgtggtgcgc ggcatctgcg cgctgcaggc aggggttccc ggcctgagcg agaacatcga
      661 ggtccgctcc atcctgggcc gtttcctgga gcattcccgg gtgttccact tcgcgggcat
      721 cgacgagcgc tggatcggca gcgcggacat gatgcaccgc aacctggacc gccggatcga
      781 ggcgcaggtg cgcgtggtgg acccgaagct gaccgagcag ctcgacgagc tgctggattc
      841 ggcgctgcac ccgcagacgc gctgctgggt gctcaattcc aagggggact gggaggcttc
      901 gccgcgcagc ggggcgcagg tccgcgacca ccagaccgag atgttgcgca ggcacggggc
      961 acaggtttca tgacgacgca ggaagaaccg gagcacgcga ccagcgcgag cgattcggtg
     1021 acggtccgcg ccgccggtgc ggtgctgtgg cgcccggacg acgacgggac tccgcggatc
     1081 gcgctggtgc accgcccgcg ctacgacgac tggacgctgc cgaagggcaa gctggatccc
     1141 ggcgagaccc ccgcgcacgc ggtggcgcgg gaagtgctgg aggaaaccgg gttcggttgc
     1201 gtgctctccg gcgaactcgc gcagatccgc tattcggtac ccgctccggg cgggtacacc
     1261 ggcaagcggg tggactactt cgccgcccgc gccgggcagg gcctgttcgc ggtgaacgag
     1321 gaagtcgacg agctgcgctg gctgagcacc gcggccgcac gggaactgct gacctacccg
     1381 cacgacgggc acgtgctgga cgccttcgac gcgctgccgc tggaatcccg gacgctgctg
     1441 ctggtccggc acgccaaagc gggcaagcgt tcggaattca ccggcgacga cacgcagcgc
     1501 ccgctgtccg cggccgggct gcgccagcgg gacgccttgc acaccttgct gccgctgttc
     1561 ggcccgcagc gggtctactc ggcgccgcgg gtgcgctgca cgcagacggt gcagccggtg
     1621 gccgacgacc tcggcatcgc cgtcgccgac gagccgctgc tgaccgaaga gcagtaccag
     1681 gccgatcccg ccgcggcggt gcgcaggctg ctgcgcatcg cgggcggttc cggcacttcg
     1741 gtggtgtgca gccagggcgg tgtcatcccg gatctggtcg ggcggttgac cgaatccgcg
     1801 ggcctgcgcc cggacgaggt gctcagcagc aaaggcagcg tgtggacgtt gcggttctgc
     1861 ccggatgcga attccggcaa cggttccggg ccgctgctgc ggctggtggc cgcggattac
     1921 ctccccgacc cgaggggttg agcggggaaa tgctttgcgc agcggtccgg tagcggcggc
     1981 tcgggctttt tccggtttcc cggcggctct tcggagcagg ccgcggcgca tcgcgtcgcc
     2041 gatgccgcgc gaacccggtg gaaaacggcg atgatcccgg cgcgatcgga tcgcgccggg
     2101 atcatcggat gaacatcgcg gagcgcgtgg accggattcg gcggcaccgt ttccgctgcc
     2161 gctgaccggt tccgcctccg cagccgcgcg cggctgcgag tggtgccgtg cggtgcacgc
     2221 gaaggatttc cgtgcggtgc acgcgaaaga ctcccgtgcg gtgcacgcgg atcactcccg
     2281 tgcggtgcag gcggatgacg ccgtgcagtg cacgtgacca ctctggccca cctgggaagt
     2341 tcggctcgct caggtggcga gcgttcactt cttggtggtc ttgcgcgccg tgctcgtctt
     2401 ggcggtggag gtcttcgcgg ccgaggtctt cgctgccgaa gcggtcgatt tggtggactt
     2461 cgtcgcggat ttggtgccgg tggacttgct gccggtgctc gccttcgcag tgctcgcctt
     2521 gccggtggtg ctcttcggcg ccgccttgct cgtggtcgcc ttgctcgtgg tcgccttgct
     2581 cgtggtcgca gccttgccgg tcgtcgcggc cttgctcgcc gtcgacttgc cggtggtcgc
     2641 cgccttgctc gtggtcgcct tggtcgtggc accggtcttg gcgctggacc gggtggtggc
     2701 ggccttcttc ggcgccgcct tggtggtggt cgccgacttg gcggcggtgc tgcgcgagcc
     2761 cgcggtcttg gtcgcggtgg ccttgccggc ggtgccggtg gacttggccg cggtgccggt
     2821 ggacttggcc gtgctgcggc cggtgcccgc ggtcttggtg gcggtgctgc gggttccggc
     2881 ggacttcgtc gcggtggcgc ggggcagttt gcggctgccg ccgacgactt ccttgaactg
     2941 ggtgcctgcg cggaacgccg gaacgttggt cttcttgacc ttcacggcct caccggtgcg
     3001 cgggttgcgc gcggtgcgcg cggcgcgggc gcgcttctcg aagacgccga atccggtgat
     3061 gttgaccttc tcgcccttgt tgacgttgcg gacgatgagg tccacgacgc cttccaccgc
     3121 ctggctggcg gtcttcttgt cgccgaggcg ttcggccagt gcctcgatga gttgggcctt
     3181 gttcacttca gtccctccca ggacaacaac ggccccgtcg ggccgactca aagcccacgg
     3241 taaagcccag aacagccgaa tgccattcgc cacgcctcat tttttcgttg gggcgtggga
     3301 ctttcggctg tcctgggcgt tgctcgccgc gcttcgcgac gccgtcccgg cgaccgccgg
     3361 gaaacattgt ttttcccgca cagcagggag aaatgcgttc tccggcgggt tcccgatcag
     3421 ccttcgcgag cgggcagtgt ggccggtttg aacgccgggc ggtgctgctc gtacgtgtcg
     3481 atcgtctcgg cgtggcgcat cgtcaggccg atgtcgtcga gaccttccag cagccgccag
     3541 cgggtgtagt cgtcgagcga gaagccgacg gtgaggtctt tcgcctgcac cgtgcgctct
     3601 tgcaggtcca cggtgacttc ggtgcccggc tcgttctcca gcagcttcca cagcagttcc
     3661 acatcggact gctcgcattc ggcggccagc aggccctgtt tgcccgcgtt gccgcggaag
     3721 atgtccgcga accgggaaga gatgaccacc cggaagccgt agtccttcaa cgcccacacc
     3781 gcgtgctcgc gggacgatcc ggtgccgaag tcggggcctg cgaccagaac gctgccgttg
     3841 cggaacgcct cgttgttgag cacgaaggtc tcgtcgccgc gccatgcggc gaacagcgcg
     3901 tcctcgaacc cggtgcgcgc gacccgcttg aggtacacgg cggggatgat ctggtcggtg
     3961 tccacgttgg accggcgcag cgggacgccg acaccggtgt gcgtggtgaa cggttccatc
     4021 gttggttcct cctgttgcgc gggcggtcag tcgaggtctt ccggggagga cagcgtgccg
     4081 cgcaccgcgg tcgccgcggc gaccagcggc gagaccaagt gggtgcggcc gcctttgccc
     4141 tgcctgccct cgaagttgcg gttggacgtg gaggcgctgc gctcgccggg ggccagctgg
     4201 tcggggttca tgccgaggca catcgagcag cccgccgagc gccattccgc ccccgcggcg
     4261 gtgaagacct cgttgagccc ttcggattcg gcctgctgcc ggaccttcat cgagccgggc
     4321 accaccatca tccgcacgtc cgaggacacc ttgcgcccgt ccaggatggc cgctgcggac
     4381 cgcaagtcct cgatgcggcc gttggtgcag gaaccgagga aaacggtgtc cacgacgacc
     4441 tcacgcagcg gagtgccgcc ctgcaggccc atgtaggcca acgccttttc gaccgcgtag
     4501 cgctcggaat cctcggcgat ggcctcggga tccggaatcc gctcgcccag cggcagccct
     4561 tggcccgggt tggtgcccca cgtgacgaac ggcgtgagtt cgtcggcgtc cagggtgact
     4621 tccgcgtcga actcggcatc ttcgtcggtg cgcagcgtct tccagtacgc cacggccgcg
     4681 tcccagtcgg cgccctgcgg cgcgtgcgga cggccccgca ggtactcgaa ggtcgtctcg
     4741 tccggcgcga tcatcccggc ccgcgcgccc gcttcgatgg acatgttgca gatcgtcatg
     4801 cgggcttcca tggacagctg gcggatggct tcgccgcggt actccaggac gtagccctgc
     4861 ccgccgccgg tgccgatctt ggcgatgacc gcgaggatga tgtccttgct cgtgacaccg
     4921 ggccgcagcg tgccttcgac gttgatggcc atggtcttga acgggcgcag cggcagcgtc
     4981 tgggtggcca gcacgtgctc cacctcggag gtgccgatgc cgaacgccag cgcgccgaac
     5041 gcgccgtgcg tggaggtgtg gctgtcgccg cacaccaccg tcgtgccggg ctgggtgagc
     5101 ccgagctgcg gccccaccac gtgcacgatg ccctgctcgg cgtcgcccat ggggtgcagg
     5161 cggacgccaa attcctcgca gttgcgccgc aaagtgtcca cctgcgtgcg cgagaccgga
     5221 tcggcgatcg gcagctcggt gccggtggtg ggcacgttgt ggtcttcggt cgcgatcgtc
     5281 aggtcgggtc gccggaccgg ccggtccgcc agccgcagcc cctcgaacgc ctgggggctg
     5341 gtgacttcgt gcacgaggtg gaggtcgatg tagagcaggt cgggctcgta gccctcgcct
     5401 cggcgcacga tgtggccgtc ccagaccttc tccgcgagcg tgttgcccat cgctcctccc
     5461 gatcgaaagg tggtggtcgc accgctgccc agcgggcaag cagaccctgc gcagcggcac
     5521 tgtcccaaga agtggacttc tcagatgacg agaagttagt atcggtacgt gggacagcat
     5581 agcggcatcg gagtgttgga caaggcagtg gccgtgttgc aggccgtggc cgaagaacct
     5641 tgcggcctca cggagttgtg cagccgcacg ggtctgccgc gggccaccgc gcaccggttg
     5701 gcggtgggcc tggaggtgca ccggatgctg cgccgcggct cggacggccg gtggcgcccg
     5761 ggtgcgtcgc tggcggaatt ggccggtggc gcggtggatc cgctgctgga ggcgtcgtcc
     5821 acggtgctgc ccaaactgcg ggaagtcacc ggggaaagcg tccagctcta ccgcagggac
     5881 ggtttgcagc ggctgtgcat cgcttccgcg gaaccgccga gcgggttgcg ggacacggtc
     5941 ccggtcggct cgacggtgtc gatgatggcg ggctcgggcg cgaaagtcct tgcggcgtgg
     6001 gcggatccgg ccacccaacg agcggtgctg gccgaggccg tcttcggcga gcgcacgctg
     6061 ctggaggtcc gccgccgcgg ctgggcgcaa agcgtcgccg aacgcgagtc gggtgtggcc
     6121 agcgtctcgg ccccggtccg cgattcgcag ggcacggtgg tggcggccat cagcgtttcc
     6181 ggcccgatcg accgcatggg ccgccgaccg ggcgcccgct gggccgccga cctgttggcg
     6241 gccgcggatg ccttgcagaa ccgcatctga tccttcgggg cccatccgtc ttcggggccg
     6301 tcggctttcg gggctcatcg actctcgggg cccgtcgacc ttcgcggcgc tggcggattt
     6361 ccgggcgccg tcggccttcc gcgcaacggg agatgtcgct cggtccttcc cgccgctgcc
     6421 gacgaagtga gcggcgaacc gctgacccgg cgcagcgacg ccgtgcggac ggcacatcgg
     6481 accggacgga ccgctctggg ccgagcggcc ggatggttca ggcgtgccgg cgcacgagcg
     6541 cgtactcgaa gggcaagtgc aggaaggttc cgtcgggcaa cgggacgcgg gaggacagcg
     6601 ccagttcccc ggcctccagc accagccacc cgtgccgccg gtacagcccg gtgagccctt
     6661 gagcggggag ctcggcgggc cacaggcccg tcgtcgccgc ctcccggatc gcttcgggcc
     6721 actcgccgaa gcactccgcc aactcggcga gggactcggt gaagcgttcg gagagctcga
     6781 cgtcgaagac ccgcccgcgc tgcccggtca gcacggcgag gccggccaac gcgttcggcc
     6841 actgctccgc tgccatcgcg tgcagcacgc cgcgcaggtg cacgttcgcg tcgccgatgc
     6901 gctcgtgcag cgcccggacc gcggccaagt cggtgctgtc gagctgttcg tagcggaccc
     6961 cggtgtgccc gttccccgtg cgcccgatcc tggtgcgccc gatccaggtg ttcccgttcc
     7021 cggtgtgcgc cttctccagc gccgcggcgg cgacgtcggt gccgagcacg gtctcgaagt
     7081 gctcggcgaa gtgctcggtc aacccgccgt tcccgcaacc ggcgtcgacc agcggcagcc
     7141 gggagtcgaa ccccgcgagc agcatcggca ggtagggggc catgtcctcg gcggtgccga
     7201 agtgccacgg caccggcagg tccgggctgg tcccggccag ctgccaatag gactcccaag
     7261 cgccgggttc attcgttccg gtggattcgg ccatcgcctc gccccttctt cggccctgcc
     7321 gcacgaccgg caggtgtggc tgcattgcac agcccgggca ccggctcgcg ggtcgcacat
     7381 atctggcgag caccaaagta gtccgcgatt tcgcctggtg gtcgcggttg cccgcgatac
     7441 cgctcgatgg tggcgcgaga aaaccagccc tgccgaaatt ttgatcgcga catgaaaaat
     7501 ccagccgaaa tgttccggac gccgcgccta ttgcgaaccc gaacccccag gaggaagatc
     7561 gcgccgaaac cggcgtgcgg cacggaggcc ggttcggacg aggaggtcat cgtggcagaa
     7621 cagtccggcg cgcccgaatt cgtcaaggag aacgtcgatt tcgaagcctg ctaccagggt
     7681 cagcgctttc tggcgggaac cgatctgacc ttcccggtgg ccccctggga catcggcgaa
     7741 ccgcagcccg ccctggtgga gctggccgac cggaccgcgt tctccggcga tgtcctcgac
     7801 gccggctgcg ggctcggcga gaacgcgatc ttcctggccg gtcgtggcta ccgggtgacc
     7861 gcgttcgact gctcgccgac agctctggac cgcgcccgcg cgcgggcccg cgaatgcgcc
     7921 gcccaggtcg agttcgtgca ggcggacgcc actcggctcg gcgagctcag cgggcgccgc
     7981 ttcggcaccg tcgtggacag cgcgctgtac cactgcctcg gtgcgcagca gcagcaccga
     8041 tacgccgccg ccttgcacga ggtcaccgaa ccgggcgcgc gactgcacct gctgtgctgg
     8101 gcggtggcgg gcgaggacgc ggccgtgcgg catccgatgg gcgtcggcga gcagagcatc
     8161 cgggccacct tggacgctcg ctgggaagtt ctggaagtgc gcaccgcgca gatttccacc
     8221 gcgctgatcc gggacgcgct caccgaggcg gacatcgccc tgttcgcgcg gaaaggggtc
     8281 ggcatcgacc cgggcagggc ggcggtcgac gaccggggaa ggatttccgc gcctgcctgg
     8341 ttcgtgagcg cggtgcgccg ctgaggacgc ggcgcttttg cgctttcccc gcgatttgaa
     8401 aaaccccggc gaaatgtttc cgctaccgat cgcccttccg ggtgatcatg gatgtggcga
     8461 accggcgaac tgcgacataa tccgttttgt gcgaacagct gggggaagat ctcacgtggc
     8521 ggcggaaccg cccgccgtgg cgattctcgg cgccgggatc gcgggactgg tggcggcgca
     8581 cgaattggaa aggctggggc attcggtcat cgtgctggag ggcagcggcc gcatcggcgg
     8641 acgcgtgttc acccaccggt tcggctccgc cgacaacgcc ccttacgcgg atttgggcgc
     8701 gatgcgcatt ccgaccggtc acgcgctgac catgcgctac gtggacgaac tcggcctcac
     8761 gcccgcgctg cgcccgttcc gcacgatcct gagcgacccg aacaactacc tggcgaccgg
     8821 ccgcggcttc gtccgggtgc gggacgcggc cgggccggtg gtcgaggacc tgcggtgcgc
     8881 ggtcccggtg gattccttcc ggcgggacac cgtgctgttc tgcgcctggc tggccgcgct
     8941 cgcccgggcg gtgggcccgc gtgcgctgcg cacgggcctg gccgcggaga tcaccccgat
     9001 gctgcgcgca gccgaccgcg tcgacctgtc gtcgtacgtg cacgggccgg ccgaccggtt
     9061 cgacctggtc ggcgccttcg acacccatcc gcaactgcgc gaggcgtgcg gcgtccggct
     9121 ggccgggttc atcgacgacc tgctgctgga gaccggaacc cggctgcggt acctggcggg
     9181 cgggatgggc cggatcaccg accggctggc cgcccggctc cgcggcccgg tcctgctgga
     9241 ccgggaggtc gtgagcttgc acgtccgcgg cgaccaggtg ctcgtcgggc tgcggcaccg
     9301 gggcgtcgac gtgctctcga gatatccggt cgcggtgtgc acgctgccgt tctcggtgct
     9361 gcgcgagctg cagctggcgg gcttggacga cgacaagcgg gaggtgatcc gcagcgtcga
     9421 gtacgcggcg gccacgaaga tcgcactgca ctgccgggag cccttctgga aacgcgccgc
     9481 ggtctcgggc ggcgcgtccg cgaccggcgg gcggctgcgc cagacgtact acctgccgca
     9541 ggacggcgac ccggcgttgg gcgccgtgct gctgggctcc tacgcgatcg ccgaggacgc
     9601 cgccccgctc ggccggttgc ccgccgaccg caggcacgcc gcttcgctgg aggagctggc
     9661 cgggctgcac ccggagctca aggcgccggg cgccgtgctc ggcgccgcga gcatctcctg
     9721 gggcgaccac cgctggagca agggctgcgc cgcgcaccgc tggcggtggg gcaaggacgc
     9781 ggcggcggcc agggccgagg gaatgcgcgc ggcccgcccg cagggagggc tgttcttcgc
     9841 cggtgagcac tgctcgtcca ctccggcgtg gatcaacggg gccatcgagg cggcgctggc
     9901 cgtcaccggc gccgtggacg cggcgttgcg gaccggtgcg gccgaccgcg cgcaacgatc
     9961 gtgagcgccc gcgcggcgca gcggtgaaca gggggaaaca gtgagcatct tcgacctgcc
    10021 ccggctgcac ttcgccggta cggcgatcac ccgactgccc accggcccgc gcagcgggca
    10081 ctacgacctg gccgcgaacg aggcgctgac cgcggacggc acgccgttcc cgcgggaccg
    10141 gcctgccgcg gagtaccacg agcacctcga cgggctcggc gagcgcttcg aacccgacgg
    10201 ccggctccgg ccggacgggc ggttcggcac cgccaagggc tggaacttcg gcggcaacgg
    10261 gcacttctgg ctggacgccc gcatcaccgg gtgggagcgc gtgccgggcg cggccggtgc
    10321 gcaggatccg gtgctcgggc gggcggtgga cctgtggggg cacttcaacg agcacctggc
    10381 gaccacgcac aaccgggctc gcgtcttcga cgtcgacccg gcgtccgact ggaccaccac
    10441 cgtgctggcg ggtcagttct gcttcggccg ccagggtcgc tcgcacgaca ccgggtacat
    10501 ggcggtcggc gcggtcgacg gcccgcagcc acctcgctgg cagaactcgc agcacgtgca
    10561 cggagtcggc gagcacccgc tggaatcctg gttccggcgc tctgtcgtgc atcagttcgc
    10621 cgtggacgcc gacggcctgg agtggttacc cgaggcggag atttccgagg cggtacggct
    10681 gctgcgcgcc gcggcgggcc caggcggtct ggtcgtccgc tacgcgctga gcaacatggc
    10741 cgcaccgcga gacaacgaca ccccgaacgt ctggcaggtg cgcggcacca tcgctgcccg
    10801 cgaccccgcg gaagagcgca cttgtccggc ggggcggttg ctcaccgcgc gcgaaccccg
    10861 ccggcgcggt gaaccggctc cgctgcacaa cgccgcggtg caggtgaccg gcgagcacac
    10921 gaccttcgac ctgatcaccg cggtgcccgc gctgggacgg agcccggagc ccggtccgga
    10981 cggggtgcac cggctcgggc cgcggctgga cctgggagat ctgcagctgc gcacgcgcgg
    11041 ctccgggcag ctggtcgcgc ggttgcccag tagcgcctac cgcgcggaca ccgagcggac
    11101 cggcgggctg gtcaccgttg cgaccgagcc gggatgcgcc gcagccgagg acgagccgct
    11161 ggtgctcgtc cgcgaggggc aggagtccgc ggtgctgctc gccgaggagg agtcggtcgt
    11221 gcggatcgac gactcctgcc tgttcctcga ccccgccgag ggagacagca ccgagggaga
    11281 cagcaccgag cgggacggca gtgcggggga cggcaccgcg cgggtaccgg tccgcacgta
    11341 ccacctggga cgccccgctc cgctgaacgg cctgcgggtg gtgcagttct tcaacccgcg
    11401 cgcactgccg cgggacccgc gggcccaggc cgcggacgcc cggtgcggtg cggtgcagat
    11461 cgtgcaggtc cggccggacg aaggcgccgc ggattgggcc gaatcctgca ccttggacac
    11521 cgacgaacag ggccgagccg tgttggcggt gcgctgcgcc accgccggcg ccacccggct
    11581 gctgctgctc ccggaaggcc aactcccgcc gtgcgatccg gacgagcccg gctcagcggc
    11641 ccgcgcgtac gacaacgacg accgcacggg ctactggccc gccgtcggct gcgcggacgt
    11701 gcgcgtgctg ccggacaccc ggcacctgga cgagattccg cgcgcggagg tcacccacga
    11761 cctgctctac cgggaggtct tcgcgcccta cgagctgctg tactcgttca tggccgacga
    11821 ggtcttcagc ctggccgagc agagcaaggt gggcacttac gcgcggctga tctggctgat
    11881 gtccgacccg cgccaccggg acaagacgtt ctacatgccg ccgacccgcg acctgacccg
    11941 gccgcagggc cgcttgctgc tggcccacct gcgcaggcag caggcgcccg ctccgccgga
    12001 gctcgtggcc cggcgagatc gccccggcgc catcaccacc cgcggtcagc tgcgcgacgc
    12061 gctgcgcgag gccgcgagcg tcgaactcgc cgggatgctg cagtacctgt acgccgcctg
    12121 gtcgatcccg acgcacgagg ccgggcagca gctggtgcgg cgcggcgagt ggaccgccga
    12181 gcagctgcgg ctggcctgcg gcgacggcac cgagacgctg cgcaacggga tgcgcggcga
    12241 gctgctgagc gtggcgcggg aagagatggt gcacttcctg gtgatcaaca acatcatcac
    12301 ggcgatgggg ttgccgttcc acttgccgga catcgacttc ggccgcgtca accaccgtct
    12361 gcaggtgccg ctcgacctgg ccttggaagg gttcgggctc gggagcgtgc agcggttcat
    12421 cgcgttggag cagccgcact cgttgaccag ggagatcgca ggcgacgtcg cgccggacgc
    12481 ggccgggaag gcgtacccgt accagtcgct cagcgacctc tacgccgcca tccgggaggg
    12541 catcggcgcg gtgccggacc tcttcctggt gcagcggggg cggggcggcg gcgagcacca
    12601 cctgttcatg cgcaggtcgc tcaacgacgt ccaccccgac taccagctgg aggtggacga
    12661 cgtccccagc gcgctgttcg ccatcgactt cgtcaccgag cacggcgagg gcaacgtcct
    12721 gcccgggccc gcggacgagg actcgcacta cgacaccttc ctgcggatgt ccgacctgct
    12781 gatggcgcac cgcgtcgagg cgcccggcca gcggtgtcca ccgtggacac ccgcgtaccc
    12841 ggtgctgcgc aatccgacgt tgcacgcggg cgacggcgcc agggaaccgg tcaccgcgcc
    12901 ggaggcgcgc tcggccatgg tgctgttcaa ccgctcgtac ttcctgatgc accagctgat
    12961 gctgcagcac ttccacggcg cggccgacgc cagcctgcgg cgctcccggc tgatgaacgc
    13021 ggctatcgac gtgatgacgg ggatgctgcg gcccatcgcc gagcacctgg tgacgctgcc
    13081 gtccggacgg cccggccgca ccgccgggcc gtccttcgag ctggaggagg agccgggttt
    13141 cctcgcccgt cccgatgtcg cgctgcgctc gctcggcggc cgcttcgacc acctcgctcg
    13201 ccaggctgcg gaacaacccg gcctgcccgc gcgggtcgca gagctgatgc gctcctacgc
    13261 cgcggagttc cgcgggtcgg caccgtgacc gcgatggtct cgcggaattc ccggtgcgca
    13321 ttcgcggtcg ggttgccgag cggatcgatg ccgccgcgat cagatcgacg aagcctcgtt
    13381 caattcgggt ccggggcctg ccagacggcg gcggccattg cgacggccac cccgtcgaag
    13441 aattgcgcac ccggcaacca cccggaatag gcgtcccgga attcctgcga actcggcagc
    13501 gtgttgagct cgcccagctt gtgccagctg gggtgcagga agaggttcaa cgcgtccgtg
    13561 gccgccccgg catcggcggt ggcccggtac acggcttcgg cgttctggaa cgcgaccggg
    13621 atgtgccagt ccgcgtcccg gcccttccgg gcgtgcaggt cggtccgctg cggttccagc
    13681 acgaccagcc gcccgcccgg ggcgaccagc gagcgcaggt gcggcaggat ctgttcgtag
    13741 ggacgcatgt ggaacacggc gctgaaggcg aaaacgacgt cgaacacgcc atccgccgcg
    13801 ggctcgacgt cgtaggcgct gcgcgcctcg tagcggatgt tcgcggccgg ccgggtccgc
    13861 cgcgcgatgt ggatcagcgc ttcggacagg tcgacgccga gcacctgcgc gtagcgttcc
    13921 gcgagcagcg ggcagtgcct gccggtaccg cacccgacgt cgagcgctcg gtcaccgccg
    13981 ggcagttggg cgtccagcca ggtgcggaac gggccttccg cgtcgatcat ccgggtggcc
    14041 atccggtcga agtgttcggc cacgtcgtcg aaaagcgcgc cgacttccgc ggaccgcgca
    14101 gcaatggact cttttcccga tgattccatg tcctggcacg atacctgcag ccgccattcc
    14161 cgttcgggtg aaatgatgcg caggatttgc acaaattccg acaattttcg gcatcgcggg
    14221 atgcgagccg atcagacact ccggcggatg gagttcgccg accggaatcg acgacgtcct
    14281 gccctggtcc agccctcggc aacggcgtcc cgcaggagtc cggggtcgcc gtgcggcgac
    14341 cactccgtcg acacgacgct cgatcacgga cacgcccgct ggtgaccgag catccgtttt
    14401 ccagcgcgaa caccgtcgcc gacctgcgca acgaacacgg acaccgcacc tccgacggag
    14461 gtgctcagtc cgtcaagtcc gtcgtgccct gtccaaccgc atcgacaggt cgccgaccac
    14521 atcgacgaga ccaccaacag cggcacaccc gacgagcgca aggctcgcac cgaagcccta
    14581 gcgccccgga ccgagatcac cgacccgagc cggctcgtcc cggtcccact cccccagccc
    14641 cgcgacaaaa cgaggccgcc cccacctcac cagcgggaac gacctcggaa ggagcggttc
    14701 gcacaatgtt tgctttggta gtcccgacgg gattcgaacc cgcgccgccg gcgtgagagg
    14761 ccggtgtcct aggccgctag acgacgggac cgcgctacac cgagaactct acaacacccc
    14821 cacaccacca agacccccac ccccattccc acactcgacg tgcgaagcac gagccccaac
    14881 ttcacctcga cgtgcgaagc acgagccccc actcacctcg acgtgcgaag cacgagcccc
    14941 cactcacctc gatgtgcgaa gcacgagcca cgcactcccc gccaccacac aaagccgacc
    15001 ccacaactca atgtgcgaag cacgagcgcc cacacagcag tggccgacca cacctgcggt
    15061 ggctcaaaac aagcgccggt ggcgaccaca catgcggagg ccccaaacaa gcagtggcaa
    15121 ccacacatgc ggaggcgacc acacacgcga gtggccccac acaagtgctg gtccccaccc
    15181 agcccctcca cacacctatg gcgaggagcc ctccccacgc aaccaccgca ccgtgggggt
    15241 ctggggggtc gccccccaga tagacagaca aaaacgggaa aaggcccgcc cccaaagggg
    15301 cgggccttga acacgcgcgt gtagccccga cgggattcga acccgcgccg ccggcgtgag
    15361 aggccggtgt cctaggccgc tagacgacgg ggcctcggcg aacgatcgcg accttcgcgc
    15421 tgatcgtgat caacgcactc ggtcttgatc ctcgcgctgg ggtaccagga ctcgaaccta
    15481 gactaactga accagaatca gtcgtgctgc cgattacacc ataccccaag ggctttgacg
    15541 ttcagcgttg ttcgtccggg cttctgggga aagtccggct cggcggccgc tgtccgtctt
    15601 gctggtgtta aatactagaa catcctcgcg ggggcgctgt aaggcacccc ctgctcgggt
    15661 cgttttcgct ggtgggcgcg gtggtggccg ggccgggtcc ggtggcggcc cggccggggc
    15721 tcaggcgagg gcgcgctcgt gtctcgtttc gtcctgcggg gccgctgctt cggggatgcc
    15781 gggcaggtcg cagacgagca gttcgggcag ctcggcgaga ctggtgatca tcgacacccc
    15841 gtccggcggg gcgtgttcgg ttccgttgcg gttgagccaa acgccgtgca ttccggcgtt
    15901 ggcggcgccg agcgcgtcgg tgtcgagccg gtcgccgacg tgcacggttt cgtgcggttc
    15961 ggcgccgacg gcggtgcagg cagcgtggaa gatctgcggg tcgggtttgg cgacgccgag
    16021 ttctccggag atgaccaggt cgtcgaaggt tccggcgagc ccggtgtcgc tgatcttctt
    16081 gcgctggtag gcgctgtccg cgttggtgat cacggcgagc cgcaggccgc tggcgcgcat
    16141 ccagtcgagg caggggcgcg cgtcgtcgaa cagttgccag gcgcgttgca tggcggccat
    16201 ccggtagtcc tcgcgggcgg cgacttcggt gtcgccgagt tgttcgccga aggcggcgaa
    16261 gaagtcccgg gtgcgttctc ggcacatggt ggcgaagtcg tactcgccgg cgacgaagcg
    16321 cgcgtagtgc tgctcggtgg tgctgcgcca caccggccag gcggcgtcgt tgccgatgag
    16381 ggcgcgcagg cccatccggg acgaggtggc gttgtccagc agggtgtcgt cgatgtccag
    16441 gcacacggcc ttgatcgggc cgggcggggg tgcgttcggc ggttcaggcg cggttgtcac
    16501 cccgagaggc taggtgatca ccgggcgtac ccgactcgac caagccggtg atactcggtt
    16561 ccctggcacg gtttagtgcc gctggggccg ttgggggtgg cggcgctccg accgccaccc
    16621 gttcagcgca tttccgcggt gttcccgtcc agtgcgcggt ggagtctgct aagggacact
    16681 tcgcggccca gcagttccat cgattcgtac agcggcgggg acacggtgcg gccggtgacg
    16741 gcgacccgca cgggcgcgaa ggctttgcgc ggtttgatgc cgagcccgtc gacgacggcg
    16801 gcccgcagcg ccgcttcgat ggagtcggtg tcccattcgg gcagctgctc gagcgcgccg
    16861 atgctcgctt cgagcaccgg gcgcgcgtct tcgccgagcg ctttctgcgc ggaggcttcg
    16921 tcgggctcga agtcttcgcc ggcgaacagg aatcccatca tgttcaccgc gtcggagagc
    16981 acgatcagcc gttcctgcac cagcggcgcg gcggcgcgca cggtttcgag ctgctcgccg
    17041 gtgggttccg cgggcagcac gccgccgtcg atcaggtacg gcaccacgcg ctgcacgaag
    17101 tcgtcgggtg cgagcgcccg caggtgcgcg gagttgatcg cgtcggcctt cttctggtcg
    17161 aaccgggcgg ggttggcgct gacccgcccg atgtcgaagg cttcgaccat ctcgtcgagg
    17221 gtgaacacgt cgcggtcgtc ggcgatggac cagcccagca gcgcgaggta gttcagcagc
    17281 ccttccggca ggaatccgcg tgcgcggtgg tggaagaggt cggattgcgg gtcgcgcttg
    17341 gacagcttct tgttgccctc gcccatgacg aacggcaggt ggccgaattc gggggtgaag
    17401 tcggtgacgc cgatgcgccg cagcgattcg tacagcgcga tctggcgggg cgtcgaggac
    17461 agcaggtctt cgccgcgcag cacgtgggtg atccgcatca gcgcgtcgtc gacggggttg
    17521 gtgagggtgt agaggggttc gccgttgccg cgcaccagga ccgggtcggg cacgctgccc
    17581 gcggggaagg tgatctcgcc gcggacgagg tcggtgaacg cgaggtcgtg ctcgggcatc
    17641 ttcagccgca gcacggggtt gcggccttcg gcgcggaatt cggccttctg gtcctcggtg
    17701 aggtgccggt cgtggttgtc gtagccgagc ttggggtcgc ggccggcggc tttgtgccgg
    17761 gcttcgacct cttccgggct ggagaaggct tcgtagagct caccggcggc gagcaggcgc
    17821 tgcgcgatgt cggcgtagat gtccttgcgc tcgctctgcc ggtacgggcc gtgctcaccc
    17881 ccggccccgg ggccttcgtc ccagtccagc ccgagccagc gcagcgcgtc cagcagcgcg
    17941 tcgtaggact cctggctgtc ccggctggcg tcggtgtcct cgatgcggaa caccagggtg
    18001 ccttcgtggt gccgggcgaa ggcccagttg aacagggcgg tgcggatcag cccgacgtgc
    18061 ggtgtgccgg tcggcgacgg gcagaaccgg gcgcggacgg tgctgtgcgg cgtggcggtg
    18121 acctctgacg tgctcatgac gcggtccagc ttagcgagcc cggttccgtg gttgaccagc
    18181 gactccggta ggaggatggt gaggttattc aacagacgtt gaatactcgc tcgggagggg
    18241 atcgcgatga cgcgaacgga acgcacgacg tgctgcatcg tcggcggcgg ccccgccggg
    18301 atggtcctgg gcctgctgct ggcccgctcc ggtgtgcagg tgaccgtgct ggagaagcac
    18361 ggcgacttcc tccgcgactt ccgcggcgac accgtgcacc ccacgacgct gcaactgctc
    18421 gacgacctgg gcctggccga gcggttcgcc gagctgccgc accgcagggt ggaccgggtg
    18481 cggctgccgg tcgggcagcg cgaggaccag ttcctgacga tcgccgactt caccaggctg
    18541 ccgatcaagt acaactacat cgcgctggtg ccgcagtggg atctgctgga cctgctcgcg
    18601 gacgaggcca agcagcaacc cggtttcgac ctgcggatga acaccgaagt caccgggctc
    18661 gtccgggagg gcggccgggt gaacggggtg cgctaccgcg aatccgacgg cagcaccggc
    18721 gagctgcgcg ccaccatcac ggtcgcctgc gacgggcggg actcgctggt gcggcagctt
    18781 ccggagctgg ggctgcggga cttcgccacg ccgatggacg tgcagtggtt caagatcccg
    18841 cgccgcgcgg acgacccggc cgggctgctc ggtctgatcg cggaccgcac cttccaggcg
    18901 ctgatcgacc gcggcgacta ctaccaggcc gcctcgatca tcgggaaggg caccgacgcg
    18961 gaacgccgcg cccggccggt ggcggagttc aacgaacggc tgcgccggtt cctgccgtgg
    19021 ctcgacgacg gccgcgacct ggtgcgcgac tgggacgacg tgcggctgct cagcgtcaag
    19081 ctggaccggt tgcgcaagtg gcacgtgccg gggctgctgt gcatcggaga cgccgcgcac
    19141 gcgatgtcac cggtcggcgg gatcggcatc aacctggccg tgcaggacgg cgtcgccgcc
    19201 gcgcggtacc tggcgacgcc gctgcgcgag gggcggttgc ggcgcaagca cgtcgcggcg
    19261 atccagcggc ggcggtggcc cacgacggtg ctgatccagc agctccagcg ggtgctgcac
    19321 cgcaacgccg tcgccccggc gctgcgcggc gaggtggact tctacaagag cctgcccgct
    19381 ccggtccggc tggtcaccaa cgcgccggcg ctgcgggtcg tgccgccgta cgtgctcgcc
    19441 tacggcgcgc tgcgggaacg cccgccgcag gaggcgctgc gctgagcgcg ccgctgcacc
    19501 cggtctcggc ccgggccagc ggcgcagccg ctccagcagc gaccacggag ctgcgtctcc
    19561 gaggagatcc ggcagcgagc aggcgcctgc ggcgccattg cccgaaccac ctgcgcaaga
    19621 cgagctcgaa gacagggact cagcggtcct gcaccgggtt ggtcagggtg ccgagcccgt
    19681 cgatggacac cgagacctgc tggcccgcct gcatcggccc gaccccggcg ggcgtgccgg
    19741 tgaggatcac gtcgcccggc agcagcgtca tgatccgcga gatgtacgac accagcgccg
    19801 gaacgtcgtg cagcagcagc gaagtccgcg actcctgctt gagctcgccg tccagttcgg
    19861 tgcgcagtcc caggtcaccg ggatcgagct cggtgtcgat ccacgggccc agcgggcaga
    19921 acgtgtcgta gcccttcgcc cgcgtccact gcccgtcggc ctgctgctgg tcgcgggcgg
    19981 tcacgtcgtt ggcgacggtg tagccgagca gcacgtcggc gccgcgcgcc tccgggacgt
    20041 ccctgcacgg ctggccgacg accgcggcca gctcgccctc gtagtcgacc cgctcggagt
    20101 tcggcggcag cttgatcgcc gcgttcgggc cggtgaccga ggtggacggc ttcatgaaga
    20161 tgatcgggtt ctgcggcacc tcgccgccca tctccctggc gtgctcggcg tagttcttgc
    20221 cgacgcagat caccttgctg ggcaggatcg gccccagcag ccggacgtcg gccatcggcc
    20281 acttgcgccc ggtgaacgtc ggttcgccga aggggtgctg gtcgatctcg atggccagca
    20341 ccttctcctg cggggcggac gggtcgggtt ccagcgcgac gaacgacacc ccgtcggagt
    20401 gggcgactcg ggccaggcgc acgacgacct cttttcgttg cggcgttgct ttccccggcc
    20461 accctaagcc tccgggcccg cgggcttgcg gagcgcggtt tagcgaggag tgaacggact
    20521 gttcgtccga acagatcggg ccaacaggcc gtccgctcgg aaagagccgt cagtcagcgc
    20581 cgctgaggac ggtgcggcgc agcgccttgt aggcgagcgc gtcgcacagc gccagccagc
    20641 tcgcctcgac gatgttgccg tgcaccccga cggtggtcca ctcgtcctga tcgtcgcggg
    20701 actccaccag cacccgcgtg accgcgtccg tacccgcggc gtcggtgagg atgcggacct
    20761 tgtagtccac cagttccacc gagtccaccc aaggcaggtg cggaaccagc gccttgcgca
    20821 acgcggcgtc gagggcgttg accgggccgt tgccctccgc cgtggcgatg acgcgctccc
    20881 cgtccacgtg gatcttcacc gtcgcctcgg aaacgaccgt cccgtccggg cggtgatcca
    20941 gcagcacccg gtaggactcc agctcgaacg gggcgtccac ggcgcctgct tcggcctccc
    21001 ccgcggcatc catctcgcgg cgcagcagca gttccagcga agcgtccgag ccctcgaacg
    21061 accagccgcg ggcctccagc tccttgacct tgcgcaccgc gccggagacc gcctccggcg
    21121 agtcggacag gtccagcccg agctcggcgc ccttgagctc caggctcgcc cgcccggcca
    21181 tctcggtgac cagcacccgc atccggttgc cgaccacgtc ggggtccagg tggttgtaga
    21241 gctcggggtc caccttgatc gcgctggcgt gcagcccggc cttgtgcgcg aacgccgacg
    21301 acccgacgta gggctggtgg gtgtccgggg cgaggttggc gatctcggac agcgcgtgcg
    21361 agacggttgt gagctcggtc agcttgccct ccggcagcac cggcatgtcc agcttggtcg
    21421 ccaggttgcc gaggaccgcg aacaggtcgg cgttgcccgc gcgctcgccg tatccgttgg
    21481 cggtgcattg cacgtgcgtg gcaccggcct gcaccgccgc gatcgagttg gcgaccgcgc
    21541 agctggtgtc gtcctggcag tggatgccca cccggaaccc ggtgcgcgcg acgatctcct
    21601 cgaccgtgga cgcgagctgc atcggcagct gcccgccgtt ggtgtcgcac agcaccgaca
    21661 cgtcggcgcc cgcggtcatc gcggcctcca gcacccgcag cgaggcgtcc gggtcgtggg
    21721 cgtagccgtc gaagaagtgc tcggcgtcca cgaacacccg gcgcccctcc cccaccaggt
    21781 agcgcacggt gtctgcgacc atcgcgcagt tctcttcgac cgtggtgcgc agcgcccgct
    21841 ccacgtgcct gcggtcggac ttggcgacca gcgtgacgac cggcgcctgc gaatcgacca
    21901 gcgcccgcac ctgcggatct tcgtgcgctt gcgcgcccgc gcggcgggtg gagccgaacg
    21961 cgaccagcgc ggcgtggtcg agccgcagct cgcccgcggc ggcgcgggcg aagaactcgg
    22021 tgtccttcgg cagcgcgccc ggccagccgc cttcgatgaa accgaccccg agcgagtcca
    22081 gcagcttcgc caccgcgatc ttgtccggga ccgagtagga gatcccttcc cgctgggcgc
    22141 cgtcgcgcag cgtggtgtcg tagacgtgga agtcgtcgcc caggggggtc ccggccgggg
    22201 tcgtgcgagt cactggattc tcctgtcggc ttcggtatcg atgcctcgaa gcggccgtct
    22261 cgccgcgctg gtggcgggtt cctccgggca caaaaaagac cccccgcgaa tgcgagaggt
    22321 ctgcgcgccg ggggtgcgag tcgtcacccg gcgcgccgtc caataatgcg gaagctgatg
    22381 gccacgcccg tatgctgcca caaccgctcg cggcgccacc aggtgggctg ccattcccag
    22441 ctgccggacg ggcgcgcggt cccgacatgc gaaacgggcg ccctcccggc aggaaggcgc
    22501 ccgcagcgca ggaaactcga agtcgaccag gcttgccggc cggtcacgct tggactgtca
    22561 ggcttgctgg gcgacctcgc gggaggacac cagcgccgcc agccggtcgc cgatggcgaa
    22621 ggtcgcaccc ggcgccgagt ggtcccgggt ggccaggtcg aacgccaccg aagcctccac
    22681 ccggcgggcc gcctcggcct gcccgacgtg gtccagcagc agcgccaccg acagcaccgc
    22741 ggccgtcggg tcggccgcac cgtgcccggc gatgtccggg gcgctgccgt gcaccggctc
    22801 gaacatgctc gggttgcgcc gggtggcgtc gatgttgccg ctggcggcga gcccgatgcc
    22861 gccggtgacc gccccggcca ggtcggtgat gatgtcgccg aacaggttgt ccgtgacgat
    22921 cacgtcgaac cggctcgggt cggtgagcat gtggatcgtc gtggcgtcca cgtgctggta
    22981 ggcgaccgtg acgtcggggt gctgcagcga gacctcttcg acgacccggg accacaacga
    23041 gccggcgtgg gtgagcacgt tggtcttgtg caccagcgtc aggtgcttgc gcgggcgggc
    23101 cgcggcgcgg gcgaaggcat cgcgcacgac ccgctccacg ccgaaggccg tgttgatgct
    23161 gacctcggtc gcgatctcgt gcgtcgtgtc cttgcgcagc agaccgccgt tgcccgcgta
    23221 cggcccttcg gtgccttcgc gcaccacgac catgtccacg tcgccgggat cggccaccgg
    23281 gctcttca
//
