LOCUS       NZ_CP066763            20609 bp    DNA     circular CON 30-NOV-2024
DEFINITION  Burkholderia ambifaria strain BJQ0010 chromosome 2, complete
            sequence.
ACCESSION   NZ_CP066763
VERSION     NZ_CP066763.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia ambifaria
  ORGANISM  Burkholderia ambifaria
            Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
            Burkholderiales; Burkholderiaceae; Burkholderia; Burkholderia
            cepacia complex.
REFERENCE   1  (bases 1 to 2704441)
  AUTHORS   Xu,Y.
  TITLE     Complete genome sequence of Burkholderia ambifaria BJQ0010
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2704441)
  AUTHORS   Xu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2020) School of Food and Chemical Engineering,
            Beijing Technology and Business University, No. 11, Fucheng Road,
            Haidian District, Beijing 100048, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016458785.1-RS_2024_11_30
            Annotation Date                   :: 11/30/2024 03:04:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,760
            CDSs (total)                      :: 5,675
            Genes (coding)                    :: 5,537
            CDSs (with protein)               :: 5,537
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 88 of 138
            Pseudo Genes (incomplete)         :: 78 of 138
            Pseudo Genes (internal stop)      :: 12 of 138
            Pseudo Genes (multiple problems)  :: 34 of 138
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:03:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 373143
            Orig. end                         :: 393752
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066763.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10609](-)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10609)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     misc_feature    406..419
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            complement(695..2842)
                     /locus_tag="JG536_RS17770"
                     /old_locus_tag="JG536_17770"
     CDS             complement(695..2842)
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016101.5"
                     /locus_tag="JG536_RS17770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17770"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_175667445.1"
                     /transl_table=11
                     /translation="MDNEGETDMGMENIEHVVVLMLENRSFDSLLGWLYEHDAPTLNIP
                     EATRGDEFRGLSGLDLKEFINTADNGLSSPPVRGAQGFSVPSVAPGEEFEHVNMQLFGS
                     KKPGPEDVATMSGVLQDFVNVMRIKNYKDEDIQKTAPTIMQTYTQQQLPVLSQLARHYA
                     VCDAWFASVPSQTNPNRAFLLTGTSHGLVNNGQLETDDRGKLFAGLGLAIGDDRFPEDT
                     IFNALNTAGHDWAVFWQTSYLPQKIANLASAVSMLRDLFKFLPPGEVDGLRALVEWLGK
                     YSDYIGELTNGRVASTYTRRLFQQSLEKIDGVDQCFKTLDQFHKLARVGRLPKFSYIEP
                     IWTISHDATNDGAIAQVQNLVTQIGNDYHPPGNMIVAENFVKDVYASLIANQDAWNKTL
                     LLITFDEFVGSFDHVPPPTALSPWETPPDFSTNGFDFKRYGARVPTILVSPWIQKSTVF
                     RSTTDVPFDHTSVIATTLKWLGQDSQLTSFGQRASSAPTFENALTLKQPRTDAGDVGFL
                     NVTRTIGDPIKFGDLILLRNGNNRYVSTASRAMKIGPNLPDSLMAFAVDLNLAAYFPTI
                     GNNTKATLSFQASQASQLDDSSQVQDGALLFIVTQESDVHADIFLGAWKDSHDCYYFKN
                     YVQGNYAHSEGWFVRQMDPNRGGQPLCYGDKIYIETNSDYYKGQRLTQDTRIGQGQWIT
                     TVKPGNGEDCWTVLPAITDGL"
     misc_feature    2899..2919
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.97"
                     /tool="antismash"
     misc_feature    3028..3043
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    3135..3150
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.4"
                     /tool="antismash"
     gene            3424..3729
                     /locus_tag="JG536_RS17775"
                     /old_locus_tag="JG536_17775"
     CDS             3424..3729
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JG536_RS17775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JG536_17775"
                     /product="hypothetical protein"
                     /protein_id="WP_175667446.1"
                     /transl_table=11
                     /translation="MPQPTIMVWGSVDENGNKINGSDNFSVESNGNGRYKIYFNCGYST
                     VPAVVASQNGYGQDDQSNLDGVVVPFVNQSYCQINTGNSIATHLQNRSFAFIAIGT"
     misc_feature    4095..4112
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.17"
                     /tool="antismash"
     gene            4393..4743
                     /locus_tag="JG536_RS17780"
                     /old_locus_tag="JG536_17780"
     CDS             4393..4743
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013964.5"
                     /locus_tag="JG536_RS17780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17780"
                     /product="HNH endonuclease"
                     /protein_id="WP_233410247.1"
                     /transl_table=11
                     /translation="MKPCKHRGCGALVADGKTHCDQHAHEAVNWKPDAVRGNRHARAYG
                     SAWERIRLRILRRDRSLCQPCLQTGRVTVAVAVDHVTSKARGGTDRDENPRCSCPTCRT
                     SRDRPQPARAGR"
     misc_feature    4777..4795
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 28.33"
                     /tool="antismash"
     misc_feature    complement(4778..4796)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 27.34"
                     /tool="antismash"
     gene            5054..5191
                     /locus_tag="JG536_RS17785"
                     /old_locus_tag="JG536_17785"
     CDS             5054..5191
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JG536_RS17785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JG536_17785"
                     /product="hypothetical protein"
                     /protein_id="WP_199569587.1"
                     /transl_table=11
                     /translation="MTVVFELIFRNATGGGRGFGNMTTGLLRTARLKVGKIFKEVRSLE
                     "
     misc_feature    5132..5134
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5341..6045
                     /locus_tag="JG536_RS17790"
                     /old_locus_tag="JG536_17790"
     CDS             5341..6045
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006974 - DNA damage response [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011657096.1"
                     /locus_tag="JG536_RS17790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17790"
                     /product="SOS response-associated peptidase family protein"
                     /protein_id="WP_175668366.1"
                     /transl_table=11
                     /translation="MPSNYVAPGEDPGLSELKIDSFRDLYRWTPWKPEIYQDYDAPIVA
                     SIDGEFKPLIAGFGFWPRALQKANVEKAKEQGRKPPIMRSTMNVRDDNLGKSPLYGPTW
                     RSGVRCLIPAQYVIEPSYPDARQDTNGKWVLGACVWQKIGVVARETMCVAGIWRTLKDS
                     DGRPRHVMTMITVNADGHPIMSRMHKPADEKRSVVILRPDDWDEWLTTSNVEAARAMLQ
                     LYPADDMVAEPK"
     gene            complement(6172..7008)
                     /locus_tag="JG536_RS17795"
                     /old_locus_tag="JG536_17795"
     CDS             complement(6172..7008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004355978.1"
                     /locus_tag="JG536_RS17795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17795"
                     /product="macro domain-containing protein"
                     /protein_id="WP_175667448.1"
                     /transl_table=11
                     /translation="MAKVKFLDRRLRKKFLEFTSVISASLSVFALFVDIPKGQKLLYGW
                     IFLASLLVIYLILWFWSNNLDSIDIKIEDSKVTIKTGDIFEQPGLKAIAFNEYFDTQVD
                     NVIIGEGSLNGIFIKKYLKVPASELDHHIDNYSFDRSEVLGKNDDRKHGKKVQYQIGTV
                     CIYKDYLLTAFSKFDENNKALLTMPEYLEFLITFWDKVNNIYAQQSVSTTIFGSGITRI
                     KGHKNISDEDLLKIMLWTFRISEMRFKYPAKLTIVIHKDKIDQINLLDIKSVRNGV"
     misc_feature    complement(6427..6429)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6883..6885)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6886..6888)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6916..6918)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7041..7841)
                     /locus_tag="JG536_RS17800"
                     /old_locus_tag="JG536_17800"
     CDS             complement(7041..7841)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020509.5"
                     /locus_tag="JG536_RS17800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17800"
                     /product="TIR domain-containing protein"
                     /protein_id="WP_233410223.1"
                     /transl_table=11
                     /translation="MQYPAAARYSTKTTPKLTLQGHGRRVAALHSSSQSKMPLQSDVDC
                     RIFRLPVDAGAPPHSRESPLNIQRIVFPIDLGGFMVYRNGNYTAFYVAEPFSTSALGAH
                     ATKDFCYYNLLRSWKGSDSAFPFIDSHDKTYNVRDDSNWELTLKPRLRERIRSSKNIVL
                     FLSSDTKNSRALREEIDYGINDQGLPVIVIYPEYGTKESLLYNGSLKQAVRNLWDNLPI
                     FRVSMSKVPTLHVPMDKSLIKKSLDDRDFMLSTKTSIDIYRYNP"
     misc_feature    8108..8123
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.59"
                     /tool="antismash"
     misc_feature    complement(8130..8143)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.34"
                     /tool="antismash"
     misc_feature    complement(8326..8339)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            complement(8439..8825)
                     /locus_tag="JG536_RS17805"
                     /old_locus_tag="JG536_17805"
     CDS             complement(8439..8825)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006496915.1"
                     /locus_tag="JG536_RS17805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17805"
                     /product="VOC family protein"
                     /protein_id="WP_175667449.1"
                     /transl_table=11
                     /translation="MHAHLRIARPVADLARAERMYRDAFELSVLARFADHDGFSGIMLG
                     REGLDYHFEFTHCPAHPVAPFPTPEDLIVFYLPDHGAWEAACARAAAHGFMRVASFNPY
                     WDASGQTFEDPDGYRIVLQNAQWR"
     gene            complement(9189..9950)
                     /locus_tag="JG536_RS17810"
                     /old_locus_tag="JG536_17810"
     CDS             complement(9189..9950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006483939.1"
                     /locus_tag="JG536_RS17810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17810"
                     /product="hypothetical protein"
                     /protein_id="WP_175667450.1"
                     /transl_table=11
                     /translation="MDQSQVFRAMMPGLTGAGGARIAVAYPSFPRPLPLVRLDRRGLVF
                     RAAGAAPLVCGLPRAATLLVADEPLCSLRLVIRDIAAVGDGRHDLTMQPSGAAGDELLW
                     HALREREPYRQIGQPLAPVDAAIAPIGEPQAAGDTAQRPSRSAAFRLRSHSDALFFADW
                     LEYHFDELRALSQRHGPQLQLNQLQRQVADDEVGVRFLYDIDGHATRHALTDCAREACA
                     WIEMEMRDKYAVPVAQERFGAFAAHARAGGM"
     gene            complement(10001..10609)
                     /locus_tag="JG536_RS17815"
                     /old_locus_tag="JG536_17815"
     CDS             complement(10001..10609)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195479.1"
                     /locus_tag="JG536_RS17815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17815"
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_105833364.1"
                     /sec_met_domain="Autoind_synth (E-value: 1.9e-24, bitscore:
                     83.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTFVHEEGRLPHELAADLGRYRRRVFVEQLGWALPSANESFERD
                     QFDRDDTVYVFARNAGGDVCGCARLLPTTRPYLLKSLFADLIAEDVPLPQSAAVWELSR
                     FAATGDEGGPGNAEWAVRPMLAAVVECAAQLGARQLIGVTFASMERLFRRIGVHAHRAG
                     PPKQVDGRLVVACWIDIDPQTFAALGIEPGRAARQAIAA"
     misc_feature    complement(10553..10555)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10817..11260)
                     /locus_tag="JG536_RS17820"
                     /old_locus_tag="JG536_17820"
     CDS             complement(10817..11260)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603338.1"
                     /locus_tag="JG536_RS17820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17820"
                     /product="DUF4902 domain-containing protein"
                     /protein_id="WP_175667451.1"
                     /transl_table=11
                     /translation="MTSPLLHPVRGPSPDGYVRLSENALAALALDHVASDLDASLLAEL
                     RDSAIDARLAGYTEWHRPASAGVAYLTVGWDWYLERATGTFVIAGGDVRSNIMAVDANG
                     ADLGMFRTAAALVARLAGIDWPAAVASSLLGRNATYDAGPTLQ"
     misc_feature    complement(11240..11255)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.58"
                     /tool="antismash"
     gene            11334..12053
                     /locus_tag="JG536_RS17825"
                     /old_locus_tag="JG536_17825"
     CDS             11334..12053
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006409826.1"
                     /locus_tag="JG536_RS17825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17825"
                     /product="autoinducer binding domain-containing protein"
                     /protein_id="WP_175667452.1"
                     /transl_table=11
                     /translation="MELRWQDAYQQFSAAEDEQQLFQRIAAYSKRLGFEYCCYGIRVPL
                     PVSKPAVAIFNTYPDGWMARYQAQNYIEIDSTVRDGAMSTNMIVWPDVDRIDPCPLWQD
                     ARDYGLSVGVAQSSWAARGAFGLLSIARHADRLTPAEINMLTLQTNWLANLSHSLMSRF
                     MVPKLSPESSVTLTAREREVLRWTAEGKTACEIGQILSISERTVNFHVNNILEKLGATN
                     KVQAVVKAIGAGLIETP"
     misc_feature    11340..11342
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12111..12818)
                     /locus_tag="JG536_RS17830"
                     /old_locus_tag="JG536_17830"
     CDS             complement(12111..12818)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897347.1"
                     /locus_tag="JG536_RS17830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17830"
                     /product="MgtC/SapB family protein"
                     /protein_id="WP_011659108.1"
                     /transl_table=11
                     /translation="MTLDFALRLFVAFACGVAIGLERQMRQRTAGLRTITLVASGACLF
                     VTLGVLTGNGVAGVTQIAAYVVSGVGFLGGGVIMRDKGSIQGINTAATLWCSAAVGVLA
                     GSGHFVPALAGTGVVLLTNTVLRGVSQAINATPVSNADLVREYQITVICLTADEVHIRT
                     LLSNSMYAKPLSFQSLTSEDVPEQPDRLKVTATLKLHPKDQQKLEQIASRMSMEKSISS
                     VSWTAKEAEPLME"
     misc_feature    12769..12784
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.44"
                     /tool="antismash"
     gene            complement(13172..14731)
                     /locus_tag="JG536_RS17835"
                     /old_locus_tag="JG536_17835"
     CDS             complement(13172..14731)
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011659107.1"
                     /locus_tag="JG536_RS17835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17835"
                     /product="TolC family protein"
                     /protein_id="WP_175667453.1"
                     /transl_table=11
                     /translation="MRVPEPPAASIAAAALATAVALAGCATSSIDLAPDAPDRPWQPQT
                     SAAGDIVPAPPLASAQRASHDYTLPASPALASVSPPAALDTAHPYTLPELIDLAESTNP
                     LTRIAWNDARNAALAVGIAKAAYLPNLSATAMGAYQTSHGSTSTILGDASSNTTVHGTI
                     SALSLQWLLFDFGGRAARVEAAEQASVASNVAFTAVHQQVIHDVTVAYYRYEAARARAA
                     SAQQGLTNADAILAASRARLKQGVGTVVELAQSTQNRAQANLALVQANGAQSDSYLALV
                     SALGISPLSKPSIAALPKRPLPPALASSVDAIVSDAIARRPDLQGAYALEQANRAKIKA
                     AEAAFMPKVFLSASTSYASGGTAISALPAIGDQAPTVNLNGSRYGGGVFFGVTIPLYDG
                     GLRSAVLMQARNDAQSASARLTRTKEEAVRQVVAAQNAVQTSLASHDAAKALVDAAQTS
                     YDAALTAYRNGVGSVTDATIAQSQLLAARNAEVDSYAGALSAAAALALATGTIGSSQAP
                     SQ"
     gene            complement(14718..16808)
                     /locus_tag="JG536_RS17840"
                     /old_locus_tag="JG536_17840"
     CDS             complement(14718..16808)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011659106.1"
                     /locus_tag="JG536_RS17840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17840"
                     /product="FUSC family protein"
                     /protein_id="WP_175667454.1"
                     /transl_table=11
                     /translation="MARPAADVRAPGPREILRLLAPFPGRTSIAVRVALICALTVLVTS
                     AYGTPEAALSAYVVFFMIRADRVTSIVLAAALLLIVTIVIGLVLGIAIFSIDYSILRVA
                     CMAVLSVGLLYLTSASKLRPVGAILAMIVGFGLDQLGLAPFGEAATRALLYIWLTVAIP
                     VGVAIGVNLLIAPSPRRLALAQIAKRLRLAARRLRGDDDARAAFDASLREGDKQLLTWL
                     KLSKLEGSSSATDVAALRQAIASSTALMVGVALADREPDARLPAAFAAPIAATLDEMAA
                     ILERGGYPVDVTLALPPADALPPLARVAATDLHAAITRFAEPGAAADTTAPAPAAPVSA
                     SAAARPEPVASPAPAPRGGFFLPDARSNPDHIRYALKTTAAAIFCYLLYSQLDWSGIHT
                     CVVTCYIVSLGSTAETVEKLTLRIVGCIVGALLGTAALVFVVPALSSVGELMALVFAGA
                     WLSAWVAFGSPRIGYAGFQIAFAFFLCVIQGAGPGFDLTIARDRTIGILLGNVVVYLVF
                     TRIWPVSIGKQIDVALAALLEQWRRVVQIAQPAERRTLAAEAFARHGAIAQELGLVHYE
                     PSWVRPAATWLATRRRALAELGALEGPLFLLAERAPGDAAIGARLARVVALRDGDPAAD
                     TAAPAPPSTASAATMPAPPPAATPADPARDALLNLIDTRLAHIADAARQATPKEPAPHA
                     RP"
     gene            complement(16789..17838)
                     /gene="mdtN"
                     /locus_tag="JG536_RS17845"
                     /old_locus_tag="JG536_17845"
     CDS             complement(16789..17838)
                     /codon_start=1
                     /gene="mdtN"
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006751291.1"
                     /locus_tag="JG536_RS17845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17845"
                     /product="multidrug transporter subunit MdtN"
                     /protein_id="WP_126225647.1"
                     /transl_table=11
                     /translation="MKAAGITRPSTKGRVIALAIVALGIAALAYAYHRTSAYPSTDDAS
                     IDADLVHVASPVGGRIVRLAVHENQRVAKGDLLYEIDPVPYRLTVAQAQADVELARASL
                     DTRRRSLIGEHSNAAVAAEQVKRATQNYDLATRDVNRLAPLAAQGYVSAQQFDQAKVRQ
                     RDAAVSLAQAKEQQRSSAQTIGDDADAIATLHAREAALARAQHALDDTVVRAPHDGLVT
                     GLTVLAGETLAPNQSIFTLIDASEWFAVGNFRETSLNRIAVGDCATVYSMIDRSRALTG
                     KVVGIGAGIADSDRINLPRALPIVQRSVNWVHVAQRFPVRVKLDEPDGKLVRVGASAIV
                     EVRHGSACR"
     gene            complement(17835..18128)
                     /locus_tag="JG536_RS17850"
                     /old_locus_tag="JG536_17850"
     CDS             complement(17835..18128)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012366330.1"
                     /locus_tag="JG536_RS17850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17850"
                     /product="hypothetical protein"
                     /protein_id="WP_041491666.1"
                     /transl_table=11
                     /translation="MRKTTPRVPLRAAAVLVPALPLAGCTSRGAPSYVLFGAYFPLWLV
                     SAIVGIVGAIVAHRVFVATGWAATVPYQLAVCTAIGLVVAVIVWLTGTGPFA"
     gene            18590..19741
                     /locus_tag="JG536_RS17855"
                     /old_locus_tag="JG536_17855"
     CDS             18590..19741
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011659103.1"
                     /locus_tag="JG536_RS17855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17855"
                     /product="metallophosphoesterase"
                     /protein_id="WP_175667455.1"
                     /transl_table=11
                     /translation="MRSFFVRFITIGVLFHLYVGMRIIPGAFASPLARTIAALVLASFV
                     VLIPVGMFSRRFDEGWAATLVGWAGSLAMGFFSSLLVLTFLRELVLLGVVVWRHLGHDG
                     AWSGASADTALGVLVAAVLVTAIGFVGARRTAAVKRVSIPVDGLPAALDGLTIVQLSDI
                     HVGPTIKRPYIERIVRAVNALDADLVVVTGDVVDGSVKRLREHTAPLGRMQSRHGSFLV
                     TGNHEYYAGAHAWIDEFRRIGLTVLLNEHVLIEHDGARAVLAGVTDFTAGGFDPAHRSD
                     PEQALAGAPPDVATKILLAHQPRSAEAASRAGFTVQLSGHTHGGQFLPWPPFVRLQQPV
                     IGGLDRFGAMWLYTSRGTGYWGPPNRFGVPSEITLIRLTRATG"
     gene            19984..20589
                     /locus_tag="JG536_RS17860"
                     /old_locus_tag="JG536_17860"
     CDS             19984..20589
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011659102.1"
                     /locus_tag="JG536_RS17860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_17860"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_175667456.1"
                     /transl_table=11
                     /translation="MSTPDLFADAPAPDVDWYPDWLAPSDADRVLAALIDEVAWQQDTI
                     RTPRGRIPLPRLTAWQGEPDAVYVYSGIRNVPAPWTAAVLDLKRAVELTCGETFNSVLL
                     NRYRNGQDSLGWHADNEPELGDAPVIASVSLGAMRVFDLRHRATGVVHAYRLTHGSLLV
                     MRGRTQAEWQHRVPKAPAVQGERINLTFRRVVSAAAGR"
ORIGIN
        1 cgccgcagct cggccacggg cgtgtcgatt cgacgtgccg cggcttttct gaatcggatc
       61 gggcggttac ggccgacgaa cgcgcagagg aggcggatcg gaaggccgct aagcgacggg
      121 ccgaacaggt ggaacagtgc gtcgacgcgc tgacatggca ggaacgagca gcgatccaac
      181 gacacatgaa ggcgaagcag accgcggcga tgaacggggc gtgccgtgca atagtttgga
      241 gcagcccgcg ggagttcgat ttgtcgactg tccatgccga gtaccagagc gcgaaagagt
      301 cgctgaatcg gaatttaaag aagcggagcc tattggttca ggccgtccgt aagacgtgct
      361 gcgagattaa ttaaataagc accaacctga gtattcaatt tttggtggat gttcatgcgg
      421 agcctggtga gcgtggccgc taggctccgc aagatagcct gcggccgcga gcgggacgtg
      481 gcaggtggtc gtccgtcaac gcctcgcaca accgggaccc cgagttcgga tgttgggggg
      541 cgtcgtaact gtcgagcggg acagctacca cgcgtccctg gacgccgaca ttgcgtagcg
      601 catcgttcga gcgcgcaatc gagccggcta cggcattgat ataggagccg atgcgaatgt
      661 cgctcggcac tgaaatcgcc cgaatggtct gtcactacag cccgtcggtg atcgcgggca
      721 agacggtcca gcagtcttcg ccattcccag gctttacggt ggtaatccat tgtccctgac
      781 cgatacgggt atcctgagtc agtcgctggc ctttgtagta gtcactattg gtctcaatat
      841 agattttgtc tccatagcac aaaggttgac cacccctgtt tgggtccatt tgcctgacga
      901 accacccttc gctatgggcg tagttgcctt gaacgtagtt cttgaaatag tagcaatcgt
      961 gagaatcttt ccatgcgccg aggaatatgt cggcatgcac atcactctcc tgcgtgacta
     1021 tgaacaacag cgcaccatct tgtacctgac tcgagtcatc gagttgagat gcttgagatg
     1081 cctggaaaga aagtgtcgcc ttggtgttgt taccgatcgt tgggaagtac gctgcgaggt
     1141 tgagatccac cgcgaaggcc atcaagctgt caggcaagtt cggaccgatc ttcatggccc
     1201 gtgaagcggt tgatacgtat cgattgttcc cattcctgag caggatgagg tcgccaaact
     1261 tgatgggatc accgatcgtc cgagttacat tcagaaagcc gacgtcacct gcatccgtgc
     1321 gaggctgctt cagcgtgagc gcattctcga aggttggcgc gctgctggct cgctgaccga
     1381 aagacgtcag ctggctatcc tgtcctagcc acttcaatgt cgtggcaatc accgatgtat
     1441 ggtcaaaagg tacgtccgtc gtcgagcgaa acaccgtgct cttttgtatc cacggagaca
     1501 cgaggatagt cggaacccgg gccccatagc gcttgaagtc aaatccattc gtggagaaat
     1561 cgggcggggt ttcccatggg gacagtgccg tgggcggtgg tacgtggtcg aaggaaccca
     1621 caaattcgtc gaacgtgatc agaagcagcg tcttgttcca agcatcctga ttggcgatca
     1681 ggctcgcgta cacatccttt acgaaattct cggcaacaat catgttgccc ggtgggtggt
     1741 agtcgtttcc aatctgggtg actaggttct ggacttgcgc gatcgctcca tcgttggtcg
     1801 cgtcatgaga gatggtccag atcggctcga tgtaactgaa cttcggcaat cggcccaccc
     1861 gagcgagctt atgaaactgg tcgagcgttt tgaaacattg gtccacgcca tcgatcttct
     1921 cgagcgactg ctggaacaat ctccgggtat aggtggacgc cacccttccg ttggtcaact
     1981 caccgatgta gtcgctgtac tttccaagcc attcgactag ggctcgcagt ccatctactt
     2041 cgcccggggg caggaatttg aaaagatctc ttagcataga gacggcggag gccaaatttg
     2101 cgattttttg aggcagatag cttgtctgcc agaacacggc ccagtcgtgg ccggccgtgt
     2161 tcaacgcatt gaaaatcgtg tcctctggaa agcgatcgtc gccaatggca agcccgagac
     2221 ccgcgaatag cttgccgcga tcatcggtct caagctgtcc attgttaacg agcccatgcg
     2281 atgtcccggt caagaggaat gcccggttcg ggttggtctg cgacggcacc gaagcgaacc
     2341 aggcatcgca cactgcgtag tgccgggcga gttgactcaa tacgggaagc tgctgctggg
     2401 tgtacgtctg catgatcgtt ggggctgtct tctggatatc ctcgtctttg taattcttga
     2461 tcctcatcac gttgacgaag tcttgcagga cgccgctcat tgtcgccaca tcttccgggc
     2521 ccggcttctt gctcccgaag agctgcatat tgacgtgctc gaattcctcg ccgggtgcca
     2581 cactcggcac cgaaaatccc tgggcgcccc gtacgggtgg cgacgacagg ccgttgtccg
     2641 cagtgttgat gaactctttc aagtcgaggc ctgacaagcc ccggaattcg tcccctcgtg
     2701 tcgcttctgg aatatttagt gtcggcgcat catgctcgta cagccagccc agcaaactgt
     2761 cgaatgaccg gttctcaagc atgagcacga cgacgtgctc aatgttttcc attcccatat
     2821 ctgtttctcc ttcattgtcc atgtgtcacg ttggtctatt cgtgtcgcat aagagcgact
     2881 tcaacgcagt agtgagtttt cgcgacagcg tgacgacaag gaatacgggc gagacatgtc
     2941 acgaggtcgt tccgtcgagc tacatcagca ggcgagattg aagaatgcgc tttctggggg
     3001 gaagggggat gaagaaagac tctaaaaatt ggcaatcatt gtttatttta atgcaattaa
     3061 gcgatgcgcg gcgcgctaac tcatgttggt atcgggctaa gtgcgagtgt tgatcgcatt
     3121 attgaaataa tcaatcgtat tgctgtccga tttggcttgt cttcagactc catgaggcgg
     3181 ccgccggagt tcggaaaacg aatcgcacgg tgtcagagaa tatcggcaga gtcggcggct
     3241 gaaatcgagt gagacggttc gataacgaca ccccgttaga attgcgaggt ttttaaacgg
     3301 agctcagggg cgtaggcttg atgtgccgga gcgtagcggt tctggcgata gcatacttcg
     3361 ctacccgacc tcaaaagtcg aatcatatcg gatttgcgtt gaattttatg attggaggaa
     3421 ataatgccgc aacctacgat aatggtgtgg gggagtgttg atgaaaatgg aaacaagata
     3481 aatgggtcgg ataatttttc tgttgaatca aatggaaatg gcagatacaa aatctatttc
     3541 aattgtggat attcaacggt tcctgcagtt gtcgcgagtc agaacggcta cggtcaggac
     3601 gaccaatcca atctagatgg ggtggtcgtt ccgttcgtta accagagtta ttgccaaatc
     3661 aataccggca acagtatcgc cacacatctt caaaatcggt cctttgcatt tatcgcgatt
     3721 ggcacgtaac tgatgttgac atctattcgc ctaaggtgag atatcgaaac accccgtcgc
     3781 gtacctagtc taagcggtgt tgctgagatc gaccagttac cctaactggt cggtcaagcc
     3841 agatcgttca ctgatgctgt gcgcacaggt tgccagtgcc ctggcgatcc ggcaatctac
     3901 gttgactcca aaaaagactt gtaaacacgt tcgcgtttcg ctatattgac gacgtcgggc
     3961 gagaggtgcg cccgaatgaa gcccgccgga tacccgcgcg ggctttttga ttggagctca
     4021 ctgtgccaaa attgccaatc gcgatcactg tgctggtgtt gctgactgca tgtaccagca
     4081 aagacgatgc ggcgtggtta cttcgcggtt acccgattca cgacgttcag atcggcggat
     4141 acgtgccctt tgcatgcgat ggggcaaagc gaatggggcg ccactactct gcgacggaca
     4201 acaaaacagg ggctcgggtt gaaggcgtac tatgcgtcaa tctgttcaac aacattaccg
     4261 taataactga ggtcgagcaa agcaagtgac cgctctaacc atatgattgc aagcccgcaa
     4321 ggtgaaaaac cttgcgggct ttttcatttg cttgctgcat ctgaaaagag gttctatatg
     4381 ccggctcggc caatgaagcc ctgtaagcac cgcggctgtg gggcgctcgt cgcggacggc
     4441 aagacgcact gcgaccagca cgcgcacgag gctgtcaact ggaagcctga cgctgttcgc
     4501 ggcaatcgcc atgcgcgcgc atacggaagc gcttgggagc gcatcaggtt gcgcatcctg
     4561 cgccgcgaca ggagcctctg tcagccctgt ttgcaaaccg gacgcgtaac cgtcgccgtt
     4621 gcggttgacc acgtcacttc gaaggcacgg ggaggcaccg accgcgatga gaatccgcga
     4681 tgctcttgtc cgacttgcag aacgtcaaga gatcgacctc aaccggctcg tgccggtcgt
     4741 tgaggatgaa atagtgctgc atgatgctgc tcgataaact gtatggatat acagtttatc
     4801 gcgcggtaag atggggcggt caactcaaaa aaattgggga cggccgatgt gtacctatat
     4861 gaacgccgca atttagcaag ctatctttgc cagcaacggc ccttcgggca acccgccccc
     4921 caaaaaattg gtgacaggtc acgctatctg cagtcggcca tcgccggtca gtggcaaaaa
     4981 tccccgatta cggacattca agaacgatgc ggttatgctg atggtctgag ttgccaatcc
     5041 tcacggagtt ttaatgaccg tggttttcga gctcatcttc cgtaatgcca ctggtggggg
     5101 gagaggcttc ggcaatatga cgaccgggct attacgcaca gcacggctca aggttggcaa
     5161 aatattcaag gaagttcgct cgcttgagtg atttgttgac aatttctccg ccgttcggcg
     5221 caatgtagtg aatctggaag acgttcttgc caatgtcgac tcccacaggg atgggattca
     5281 tagctgcctc cgttcaaaag taccgcgcgc gtatgatgcg ctcagtgcgc agcggcgttc
     5341 atcccatcga attacgtggc gccgggcgag gatcccggct tgagcgaact gaagatagac
     5401 agcttccgcg acctgtatcg ctggacgccg tggaaaccgg agatctacca ggactacgac
     5461 gcgcccattg tcgcgagcat cgacggggag ttcaaaccgc tgatcgccgg gttcggattt
     5521 tggccgcggg cgctccagaa agcgaacgtc gaaaaggcga aggagcaggg aagaaagccg
     5581 cccatcatgc ggagcacgat gaacgtccgc gacgacaatc ttgggaagtc cccgctctat
     5641 gggccgacgt ggcgatcggg tgtccgttgc ctgattcccg cgcagtatgt gatcgagccg
     5701 tcttatccag atgcgcgaca ggacaccaac ggaaaatggg tactcggtgc atgcgtgtgg
     5761 caaaagatcg gcgtcgtcgc ccgcgagacg atgtgcgttg ctggtatatg gcgcaccctc
     5821 aaagattccg acggtaggcc gcgccatgtg atgacgatga ttacggtcaa cgccgacggc
     5881 catccgatca tgtcccgcat gcataagccg gccgacgaga agcgatcggt cgtgatcctg
     5941 cggccggatg actgggatga atggttgaca acgtcgaacg tcgaggcagc gcgcgcgatg
     6001 ctgcagctct atccagccga cgacatggtc gcggagccga agtgatttgg aactacgcca
     6061 aaattacgcc aaattccccg tcgaggcctc tcagataagg aaaagatggg gtgttgatgg
     6121 tccccccgac aggggatcga gccggggagg cggtagtagc aaccacaaaa tttacacacc
     6181 gtttctcact gacttgatgt cgagaaggtt aatctgatca atcttgtcct tgtgaatgac
     6241 gatggttagt tttgctggat acttaaatcg catttcgctg attctgaacg tccacaacat
     6301 tatctttaga agatcttcgt cgctaatgtt cttgtgtcct ttgatgcgcg taattcctga
     6361 tccgaagatg gtggtcgata cactctgttg agcgtatata ttgttaacct tgtcccagaa
     6421 tgtgattaaa aattccaaat actctggcat cgtcagcaac gccttgttgt tctcgtcgaa
     6481 cttggagaat gctgtcagaa gatagtcctt gtagatgcaa accgttccga tctgatactg
     6541 cactttcttt ccatgttttc gatcgtcatt ttttccaagt acctcgcttc tgtcgaaaga
     6601 gtaattatcg atgtgatgat ccaattccga ggcgggaact ttgaggtatt tttttataaa
     6661 aatgccgttg agggatcctt ctccgataat tacgttgtct acctgtgtgt cgaaatactc
     6721 attgaatgcg atcgccttca atccgggttg ttcgaagatg tctcctgttt ttatcgtgac
     6781 tttgctatct tcgatcttta tgtcaatgct gtcgaggttg ttcgaccaaa accaaagtat
     6841 caagtaaatt accaaaagcg acgccagaaa aatccatccg tataataact tctggccttt
     6901 tggaatgtcg acaaataacg cgaatacgga gagcgaggcg ctaatgacgg acgtgaattc
     6961 aaggaatttc tttctaagtc gtctgtcaag aaatttaact tttgccatgg gacggactac
     7021 cctatctcag tattgggcaa ttaaggattg tatcggtaga tgtcgatgct cgtcttggtg
     7081 ctaagcatga aatctctgtc gtccaatgat tttttgataa ggctcttatc catggggacg
     7141 tgaagtgtag gtactttact catcgaaacc cggaaaatgg gcagattgtc ccagagattt
     7201 cttaccgctt gcttcaacga accgttgtaa aggaggctct ccttcgtgcc gtattcagga
     7261 tagattacga ttaccggtag tccttgatca ttgatgccgt agtcaatttc ttccctgagt
     7321 gctcgggaat ttttagtatc cgaactcagg aataggacga tgttcttgga gcttcggatc
     7381 cgctccctaa gtctcggttt caatgtcagc tcccagttgc tgtcatcgcg gacattgtaa
     7441 gttttgtcat gtgagtcaat aaaggggaat gcgctatcac tacctttcca cgaccgcagc
     7501 agattgtagt agcaaaagtc cttcgtcgca tgagctccca atgcgctggt gctgaacggt
     7561 tcagcgacat aaaaggccgt gtagtttccg tttcggtaca ccataaatcc tccaaggtct
     7621 attgggaaaa cgatacgctg gatgttcagc gggctttcgc gcgaatgtgg aggcgccccc
     7681 gcatcgactg gcaatcggaa tattctacag tctacatccg attgaagtgg catttttgac
     7741 tggctcgaag aatgaagtgc ggcaacgcga cgaccatgac cttgaagcgt aagtttcggc
     7801 gtagtttttg tagagtatct agctgcggcg ggatattgca ttacttcgaa gagaacgagt
     7861 aagcgcgttc gacgcgcggg cacccgaatg gacgccgcgc ggatttggcg aacaccgggc
     7921 ggggcgatgc gccccgctgc attcaattct cgtcgtcggt gctggtggcc gtcgacgctt
     7981 gttgccggtt cacgcgacga tcgcgattgc gtcactcctt cgctttgcgt tcgggctcgt
     8041 tactgcgcta tcgaaagcgc acctgcaggc tgacgcatcc cgcgctccct ctacatcacg
     8101 atcacggttg accgcttcgt cgaagatcga aaccgaacgt ttgacgttgc gtcgccggcg
     8161 cccggacgat gcagccgcgc tggtggcgat gcatacagat cccgccgtga ccgcatggct
     8221 cgcgcgtggc cgatgtgggt tgcgtgccga tgcacgggca accatcgcac gcttcgaagc
     8281 gcaatccgac gcacgcaagc aatctcggca gtcatcctgc gtagccgcaa ggacatgcgt
     8341 tgcgacggca aatgctgttt gtcgcgcgtt tgttgcgcgc gatgactatt catcccgccg
     8401 ccgatctcag cgcgtaacgg ttcggtcatg cctgcccgtc aacgccattg cgcgttctgc
     8461 aggacgatcc ggtaaccatc ggggtcctcg aacgtctgtc cggaggcatc ccaatacgga
     8521 ttgaacgacg ccacgcgcat gaagccgtgc gcggctgcgc gtgcgcatgc ggcttcccag
     8581 gcaccgtggt cgggcagata gaagacgatc aagtcttcgg gcgtggggaa gggtgcgacc
     8641 ggatgcgccg ggcagtgcgt gaattcgaag tggtagtcga gcccttcgcg tccgagcatg
     8701 atgccggaga agccgtcgtg atcggcgaag cgcgcgagta ccgacaattc gaacgcgtcg
     8761 cgatacatgc gctcggctcg ggcgaggtcg gcgacggggc gggcaatgcg caggtgggcg
     8821 tgcatgacga cgtcggctcg gcgtgacggt tcgccgatga taagccgccg ggccacggtg
     8881 aatgtgccga cagcacggaa ttttgatgtg tccccgctaa accacgcggc aagaaaaagc
     8941 ccgctcctgg gagcgggctg aatccatgtt tggagacatg gaggagacag atgtgacttt
     9001 aagggaaaac ccgagggatg gcaagtccta gttgtaattg tgcaacgcag cgcgaactgt
     9061 tttcccggca agagcagagc actgcgtatc gcggcccttc ccgcgatccg acatgtcctg
     9121 ccacggaata tttgccgttc gacccaccga tcgtcgcgta tccgcgggcc cccctcactc
     9181 tcacatgctc acatcccgcc agcccgcgca tgcgcagcaa atgcgccaaa ccgctcctgg
     9241 gcaaccggca ccgcgtactt gtcgcgcatt tccatctcga tccacgcgca ggcctcgcgc
     9301 gcgcagtcag tcagcgcgtg ccgcgtcgcg tgtccatcga tgtcgtagag gaaccgcacg
     9361 cctacttcgt cgtcggcgac ctgtcgctgc aactgattga gctgcaattg cggcccgtgc
     9421 cgctgcgaca gtgcgcgcaa ctcgtcgaag tgatattcga gccagtcggc gaagaacagc
     9481 gcatcgctgt ggctgcgcag acggaacgcc gcgctgcgcg acggacgctg cgcggtgtcg
     9541 cccgcagcct gcggctcgcc gatcggtgcg atcgccgcat caacgggcgc gagcggctgc
     9601 ccgatctgcc ggtacggttc gcgctcgcgt agcgcgtgcc acagcagttc gtcgccggcg
     9661 gcacccgacg gctgcatcgt gaggtcgtgc cggccgtcgc cgacagcggc gatgtcgcga
     9721 atcacgaggc gcagcgaaca gagcggctcg tcggcgacca gcagcgtcgc cgcgcgcggc
     9781 agcccgcaga cgagtggcgc ggcgccggcc gcccggaaca cgaggccgcg gcgatcgagc
     9841 cgcacgagcg gcagcggccg cgggaacgac gggtaggcga ctgcgatgcg ggcgccgccg
     9901 gcacccgtca agccgggcat catcgcgcga aagacctgag actggtccaa ggtggttctc
     9961 cttcgttacg atgccgcggc cggactacgc gcgttccggc tcaggcggcg atggcttgcc
    10021 gggcggcccg tcccggctcg attccaagtg cagcaaacgt ttgcggatcg atgtcgatcc
    10081 agcacgcgac aaccagacga ccgtccacct gcttcggcgg ccctgcccgg tgcgcgtgca
    10141 cgccgatccg gcggaacagc cgctccatgc tcgcgaacgt cacgccgatc aactgccgcg
    10201 cgcccagctg cgccgcgcat tcgacgaccg cggcgagcat cgggcggacg gcccactcgg
    10261 cattgcccgg accgccttcg tcgccggtcg ccgcgaaccg cgacagctcc cagacggcgg
    10321 ccgattgcgg cagcgggacg tcttcggcga tcaggtcggc gaacagcgac ttcagcagat
    10381 acgggcgggt ggtcggcaac aggcgcgcac atccgcacac gtcgccgccg gcgtttctcg
    10441 cgaacacgta gacggtatcg tcgcgatcga actgatcgcg ctcgaaactc tcgttcgccg
    10501 acggaagcgc ccaaccgagc tgttcgacga atacacggcg ccgatagcgc cctaaatccg
    10561 ctgcaagttc gtgcggcaac cgcccttcct cgtgaacgaa ggttcgcatg ggtgtcctcg
    10621 gattgatctt tgtatgcacg cattacagcg cgcgtcccga ggaggcggta actggtaact
    10681 cttacaggta gacgtgcgcc gacgcgattt gaccggtggt aacggtttct tgatcggcgg
    10741 gattgaaata cgggcggctt ttgcttataa agagcgccag tcttgaggaa atgtcagagg
    10801 aaagcgtggc agattgtcac tggagcgtgg gaccggcatc ataggtggca ttgcggccga
    10861 gcagcgacga tgcgacggcg gcgggccagt cgatgccagc gagccgcgcg acgagcgcgg
    10921 cggcggtgcg gaacatgccg aggtcggcgc cgttggcgtc cacggccatg atgttgctgc
    10981 ggacgtcgcc gcccgcgatc acgaacgtgc ccgttgcacg ttcgagatac cagtcccagc
    11041 cgaccgtcag gtatgcgacg ccggcactgg ccgggcggtg ccattcggta tagccggcca
    11101 ggcgcgcgtc gatggcgctg tcgcgcagtt ccgcgagcag cgatgcatcg aggtcgctgg
    11161 cgacatggtc gagcgcgagc gcggccagtg cgttttcgga cagccgtacg tagccgtccg
    11221 gagacgggcc gcggaccggg tgcaacaaag gtgaagtcat gcgcggaatg tatcagcccc
    11281 gaaccggcgc tggcacctga caggtatgac agcgtgacgt tgtcggagaa ataatggaat
    11341 tacgctggca ggatgcctac caacaattca gtgccgcgga agacgagcag cagctcttcc
    11401 agcggatcgc tgcctattct aaacgcctcg gcttcgaata ttgctgttac ggcattcgcg
    11461 tgccgctgcc cgtatcgaag ccggccgtcg cgatcttcaa tacctatccg gacggctgga
    11521 tggcgcgcta ccaggcgcag aactacatcg agatcgattc gacggtccgc gacggcgcga
    11581 tgagcaccaa catgatcgtg tggccggacg tcgaccggat cgacccgtgc ccgttgtggc
    11641 aggacgcgcg cgactacggg ctgtcggtgg gcgttgcgca gtcgagctgg gcggcgcgcg
    11701 gcgcgttcgg gctgctgagc atcgcccgtc atgcggaccg gctcacgccg gccgagatca
    11761 acatgctgac gctgcagacg aactggctcg cgaacctgtc gcattcgctg atgagccgct
    11821 tcatggtgcc gaagctgtcg ccggagtcga gcgtcacgct gaccgcacgc gagcgcgagg
    11881 tgctgcgctg gacggccgaa ggcaagaccg cgtgcgagat cggccagatc ctcagcatct
    11941 cggagcgcac ggtcaacttc cacgtgaaca acatcctcga gaagctcggc gcgacgaaca
    12001 aggtccaggc ggtcgtcaag gcgatcgggg ccggactcat cgaaacgccc tgacgtggca
    12061 ccggcggcgg ggcagtcctg ccgccggatc gcatgaacgg ctgctgccgc tcactccatc
    12121 agcggctccg cttccttcgc ggtccagctc acgctggaaa tgctcttctc catgctcatc
    12181 cggctcgcga tctgctcgag cttctgctga tccttcggat gcagcttcag cgtcgcggtc
    12241 accttcagcc ggtccggctg ctcgggcacg tcctcgctgg tcaggctctg gaacgacagc
    12301 ggtttcgcat acatcgaatt cgacagcagc gtgcggatgt gcacttcgtc cgcggtgagg
    12361 cagatcacgg tgatctggta ttcgcgcacg agatcggcat tcgacacggg ggtcgcgttg
    12421 atcgcctggc tgacgccgcg cagtaccgtg ttggtgagca gcacgacgcc cgtgccggcc
    12481 agcgccggca cgaagtggcc tgagccggcc agcacgccga cggcggccga gcaccacagc
    12541 gtcgcggccg tgttgatgcc ctggatcgaa cccttgtcgc gcatgatcac gccgccgccg
    12601 agaaagccga cgcccgacac gacgtaggcg gcgatctgcg tgacgccggc cacgccgttg
    12661 ccggtcagca cgccgagcgt gacgaacagg cacgcgccgc tcgcgacgag cgtgatcgtg
    12721 cgcaggcccg ccgtgcgttg ccgcatctgg cgttcgaggc cgatcgcgac gccgcaggcg
    12781 aacgcgacga aaagacggag tgcgaaatcg agagtcatga gtgtcctgcc gtgcaatgag
    12841 cgcatgccgg cccgcgtcgc gtcggcgcga tgccgaacgc ggcacgatgg ccgtcatcgc
    12901 gcggcactgt accgcgcgaa tgcgtcattc agtgtgaaac gggaggcgtg cgggctcgcg
    12961 gaacgcgagc cgcggcagga gaactgcgtc ggacaggcgt tcaggcggca agcggcgcac
    13021 gcaacggagt gctgcaactg tccacgatgg ttcctgaagg aagaatgggc ggcattctag
    13081 tcggccgccc gcgcacccgt caaccggctg ggcggccggc cgcgcacggc cggcgcctca
    13141 ctgcgacggt gactgcacgc taccgcgacg gttactgcga cggtgcctgc gacgacccga
    13201 tcgtccccgt cgcgagcgcg agcgcggcgg cggccgacag cgcgccggcg tagctgtcga
    13261 cttccgcgtt gcgggccgcg agcagctggc tttgcgcgat cgtcgcatcg gtgaccgagc
    13321 ccacgccgtt ccgatacgcg gtcagcgccg cgtcgtagct cgtttgcgcg gcatcgacga
    13381 gcgcctttgc cgcatcgtgc gacgcgaggc tcgtctgcac cgcattctgc gcggcgacga
    13441 cctggcggac ggcttcctcc ttggtccgcg tgaggcgcgc ggacgcgctc tgcgcatcgt
    13501 tgcgtgcctg catcagcacc gccgagcgca ggccgccatc gtatagcggg atcgtcacgc
    13561 cgaagaacac gccgccaccg tagcggctgc cgttcaggtt gacggtcggc gcctggtcgc
    13621 cgatcgcggg cagtgcggag atcgccgtgc cgccgctggc ataggacgtc gacgcggaca
    13681 ggaagacctt cggcatgaac gcggcttccg cggccttgat cttcgcgcgg ttggcctgct
    13741 cgagcgcata cgcgccctgc agatcgggac ggcgcgcgat cgcatccgac acgatcgcgt
    13801 cgaccgacga agcgagcgcg ggcggcagcg gccgcttcgg cagcgcggcg atggacggct
    13861 tcgacagcgg cgagatgccg agcgcggaaa ccagcgcgag gtagctgtcg ctttgcgcgc
    13921 cgttcgcctg taccagcgcg agattcgcct gcgcgcggtt ctgcgtcgac tgcgcgagtt
    13981 cgacgacggt gccgacgcct tgcttgagcc gtgcgcggga cgccgcgagg atcgcatcgg
    14041 cgttcgtcag gccctgctgc gcgctggccg cgcgcgcgcg tgcggcttcg tagcggtagt
    14101 acgcgaccgt cacgtcgtgg atcacctgct gatgcacggc ggtgaacgcg acgttcgacg
    14161 cgaccgacgc ctgctcggcc gcctcgacgc gcgccgcgcg gccgccgaaa tcgaacagca
    14221 gccattgcag cgacagcgcc gagatcgtgc cgtgcacggt cgtgttgctc gacgcgtcgc
    14281 cgaggatcgt ggatgtcgag ccgtggctcg tctggtacgc gcccatcgcg gtcgcggaca
    14341 aattcggcag gtacgcggcc ttcgcgatgc cgaccgcgag cgccgcgttg cgcgcgtcgt
    14401 tccacgcgat gcgggtcagc gggttcgtcg attcggcgag atcgatcagc tcgggcagcg
    14461 tgtacggatg cgcggtatcg agcgcggcgg gcggcgacac cgatgcgagc gcgggcgagg
    14521 ccggcagcgt gtagtcgtgc gatgcgcgtt gcgcggacgc gagcggcggg gccggcacga
    14581 tgtcgcccgc ggccgacgtt tgcggctgcc acgggcgatc gggtgcgtcc ggcgccagat
    14641 cgatcgacga cgttgcgcaa ccggccagcg cgacggcggt cgcgagcgcg gcggcggcga
    14701 tcgacgcggc cggcggttca gggacgcgca tgaggggcag gctccttcgg ggtggcttga
    14761 cgtgcggcgt cggcgatgtg cgcgagccgc gtgtcgatca ggttcagcag cgcgtcgcgt
    14821 gcagggtcgg cgggcgtggc ggccgggggc ggggccggca tggtcgccgc gcttgctgtc
    14881 gacggcggcg ccggcgcagc ggtgtcggca gcggggtcgc cgtcacgcag cgcgaccacg
    14941 cgcgcgagcc gcgcgccgat cgccgcgtcg cccggcgcgc gctcggcgag caggaacagc
    15001 gggccttcga gcgcgccgag ttccgcgagt gcgcggcgcc gggtggcgag ccacgtcgcg
    15061 gcggggcgta cccacgacgg ttcgtagtgg acgaggccga gctcctgcgc gatcgcgccg
    15121 tggcgcgcga aggcttcggc ggcgagcgtg cggcgttcgg ccggctgcgc gatctgcacg
    15181 acgcggcgcc attgctcgag cagcgcggcg agcgcgacgt cgatctgctt gccgatgctg
    15241 acgggccaga tgcgcgtgaa tacgagatac acgacgacgt tgccgagcag gatgccgatc
    15301 gtgcgatcgc gcgcgatcgt caggtcgaag cccgggccgg cgccctggat cacgcacagg
    15361 aaaaacgcga atgcgatctg gaagcccgcg tacccgatgc gcggcgagcc gaacgcgacc
    15421 cacgcggaca gccacgcgcc ggcgaacacc agcgccatca gctcaccgac cgacgacagc
    15481 gccggcacga cgaacacgag cgccgcggtg ccgagcagcg caccgacgat gcagccgacg
    15541 atccgcagcg tgagcttctc gaccgtctcg gcggtcgagc cgagcgacac gatgtagcag
    15601 gtgacgacgc acgtatggat gcccgaccag tcgagctgcg aatacagcag atagcagaag
    15661 atggccgcgg cggtcgtctt cagcgcatag cggatgtgat cgggattgct gcgcgcatcc
    15721 ggcaggaaga agccgccgcg tggcgccggt gcgggcgagg cgacgggctc gggccgggcg
    15781 gcagcggacg cgctgacggg ggcggccggc gcgggtgcag tcgtatcggc cgccgcgccc
    15841 ggttccgcga agcgcgtgat cgccgcatgg agatccgttg cggcgacgcg cgcgagcggc
    15901 ggcaatgcat cggccggcgg cagcgcgagc gtcacgtcga ccggatagcc gccgcgctcg
    15961 agaatggccg ccatctcgtc gagcgtggcc gcgatcggtg cggcgaacgc ggcgggcagc
    16021 cgcgcatcgg gttcgcgatc ggccagcgcg acgccgacca tcagcgccgt gctcgacgcg
    16081 atcgcctgtc gcagtgccgc aacgtcggtg gcgctcgacg agccttcgag tttcgacagc
    16141 ttgagccacg tcagcaactg cttgtcgcct tcgcgcaggc tggcgtcgaa tgctgcgcgc
    16201 gcgtcgtcgt cgccgcgcag ccgccgcgcg gcgagccgca gccgcttcgc gatctgcgcg
    16261 agcgcgagcc ggcgcggcga tggcgcgatc agcaagttga cgccgatcgc aacgccgacc
    16321 ggaatcgcga ccgtcagcca gatatagagc agcgcgcggg tcgcggcttc gccaaacggc
    16381 gcgaggccga gctggtcgag cccgaagccg acgatcatcg cgaggatcgc gcccacgggg
    16441 cgcagcttgc tggccgacgt caggtacagc agcccgaccg acagcacggc catgcacgcg
    16501 acccgcagga tcgaatagtc gatgctgaag atcgcgatgc cgagcacgag cccgatcacg
    16561 atcgtgacga tcagcagcag cgccgccgcg agcacgatgc tcgtcacgcg gtcggcgcgg
    16621 atcatgaaga acacgacgta ggcggacagc gcggcttcgg gcgtgccgta cgcgctcgtc
    16681 acgagcacgg tcagcgcgca gatcagcgcg acccgcacgg cgatcgacgt gcgccccgga
    16741 aacggcgcga gcagtcgcag gatttcgcgc gggcccggcg cgcggacgtc agcggcaggc
    16801 cgagccatgc cggacctcga cgatcgcgct cgcgccgaca cgcacgagct tgccgtcggg
    16861 ttcgtcgagc ttcacgcgca cggggaagcg ctgcgcgaca tgcacccagt tcaccgaacg
    16921 ctgcacgatc ggcagcgcgc gcggcaggtt gatgcgatcg ctgtccgcga tgcccgcgcc
    16981 gatgccgacc accttgcccg tcagcgcacg gctgcggtcg atcatcgaat agacggtcgc
    17041 gcaatcgccg accgcgatgc gattcagtga cgtctcgcgg aaattgccga ccgcgaacca
    17101 ttcgcttgcg tcgatcagcg tgaagatcga ctggttcggc gcgagggttt cgccggcgag
    17161 cacggtcagg cccgtcacga gcccgtcgtg cggcgcgcgc acgaccgtgt cgtcgagcgc
    17221 gtgctgcgcg cgggcgagtg cggcttcgcg cgcatggagc gtcgcgatcg cgtcggcatc
    17281 gtcgccgatc gtctgcgcgg acgatcgctg ctgttccttg gcctgcgcga gcgacacggc
    17341 cgcatcgcgc tgccgcacct tcgcctggtc gaactgctgc gcgctcacgt agccctgcgc
    17401 ggcgagcggc gcgaggcggt tcacgtcgcg cgtcgcgagg tcgtaattct gcgtcgcgcg
    17461 cttgacctgc tcggcggcga ccgccgcgtt cgaatgctcg ccgatcagcg accggcggcg
    17521 cgtgtcgagc gatgcgcgcg caagctcgac atcggcctgc gcctgcgcga ccgtcagccg
    17581 gtacggcacc ggatcgattt catacagcaa atcgcctttc gcgacgcgct gattctcgtg
    17641 cacggcgagc cgcacgatgc ggccgccgac gggcgacgcg acgtggacga ggtccgcgtc
    17701 gatcgacgcg tcgtcggtgg acgggtaggc cgatgtgcgg tggtacgcgt acgcgagcgc
    17761 ggcgatgccg agcgcgacga ttgccagcgc gatcacgcgg cctttcgtgg acgggcgggt
    17821 gatgccggcg gccttcatgc aaacggcccc gtgccggtga gccatacgat cacggcgacc
    17881 acgagcccga tcgcggtgca gacggcgagc tggtagggca ccgtggcggc ccagccggtc
    17941 gcgacgaaca cgcggtgcgc gacgatcgcg ccgacgatgc cgacgatcgc gctgacgagc
    18001 cagagcggga aatacgcgcc gaacagaacg tacgacggtg cgccgcgcga cgtgcagccc
    18061 gcgagcggca gggctggcac caggacggcg gcggcgcgca ggggtacgcg cggcgttgtt
    18121 tttctcatgg tgtggacgag ctcgacgttg gggttgatgc cgggcacggc gcaatgcggt
    18181 tcgttgccgc gacgacgatt ccgcgatacg gagccgatca taaatcagcg cggtgcggac
    18241 cgccagcgat gcggcgtgcg ccggggcgcc cggcgggcgt tcgggtccgg tcgtggcgcg
    18301 gtccgcgatt ctgccagcgc atgcttgcgc agggttgctg acggactgta aaggatcgtc
    18361 agacgaaacc gcgccggcga cggttgttcg ccgatgggca ggaatcgcgg cagggatcgc
    18421 cggattgctg cgcgagcggt tgcgaattcg cgtccggtcg agtcggccgg tatctgtgta
    18481 ccatcgtgcg aaggacgcgg cgcgtggcgc ggggcatgac gagacttgac gtcacgatcc
    18541 cggccgacgc gccgcgcgac ggtggtatcg caacgaggat gagtgttcca tgcgaagttt
    18601 ctttgtccgg ttcatcacaa tcggcgtgct gttccatttg tatgtcggga tgcggatcat
    18661 tcccggcgca ttcgcgtcgc cgctcgcgcg cacgatcgcg gcgctggtcc tggcgagctt
    18721 cgtcgtgctg atcccggtcg gcatgttctc ccgccgcttc gatgaaggct gggccgcgac
    18781 gctcgtcggc tgggccggct cgctcgcgat gggcttcttt tcgtcgctgc tggtgctgac
    18841 gttcctgcgc gagctcgtgc tgctcggcgt cgtcgtgtgg cggcatctcg ggcatgacgg
    18901 tgcatggagc ggcgcgagcg ccgatacggc gctcggcgtg ctggtggccg cggtgctggt
    18961 cacggcgatc ggattcgtcg gcgcgcgccg cacggcggcg gtcaagcgcg tgtcgattcc
    19021 ggttgacggg ctgccggccg cgctcgacgg gctgacgatc gtgcaactgt cggacattca
    19081 cgtcgggccg acgatcaagc ggccttatat cgagcggatc gtgcgggcgg tcaatgcgct
    19141 cgatgcggat ctcgtcgtcg tgacgggcga cgtggtcgac ggctcggtca agcggctgcg
    19201 cgaacacacg gcgccgctcg gccgcatgca gtcgcggcac ggcagcttcc tcgtgacggg
    19261 caaccacgag tactacgccg gcgcgcacgc gtggatcgac gaattccggc gaatcgggtt
    19321 gacggtgctg ctcaacgagc acgtgctgat cgagcatgat ggtgcgcgcg cggtgctcgc
    19381 gggcgtcacc gatttcacgg cgggcgggtt cgatcccgcg catcgcagcg accccgagca
    19441 ggcgctggcg ggcgcgccgc ccgacgtggc gacgaagatc ctgctcgcgc accagccgcg
    19501 cagcgcggaa gcggcgagcc gcgccggctt caccgtgcag ctgtccggcc atacgcacgg
    19561 cggccagttc ctgccgtggc cgccgttcgt gcgtctgcag cagccggtga tcggcgggct
    19621 cgaccggttc ggcgcgatgt ggctctatac gagccgcggc accggctact gggggccgcc
    19681 gaaccgcttc ggcgtgccgt ccgaaatcac gctgatccgg ttgacgcgcg cgactgggtg
    19741 acgggcgtgc gatagcgtcg aaatcgacgc gcgccgcgat gatggtatga cacgctgcaa
    19801 atgcttcgcc gctcgccgct cgccgctcgc cgctcgccgc tcgccgctcg ccgctcgccg
    19861 ttcgccgttc gcgcgggcgg ccgcgtcacg cggcggaatg acagcgcatg gcggcgcgtg
    19921 tcgccgttgt ctaccatgca gacatgctcc atccgcaccg tccactttcc gcctgattcc
    19981 gacatgtcga cgcccgatct tttcgccgat gcgcccgcgc ccgacgtgga ctggtacccg
    20041 gactggctcg cgccgtccga cgccgatcgc gtgctggccg cgctgatcga tgaagtcgca
    20101 tggcaacagg acacgatccg cacgccgcgc ggccgcattc cgctgccgcg gctcaccgcg
    20161 tggcagggcg aaccggacgc cgtctacgtg tattcgggaa tccgcaacgt gcccgcgccg
    20221 tggacggcgg ccgtgctcga tctgaagcgt gcagtcgagc tcacgtgcgg cgagactttc
    20281 aacagcgtgc tgctcaatcg ttaccgcaac ggacaggaca gcctcggctg gcatgcggac
    20341 aacgagccgg aactcggcga cgcaccggtg attgcgtcgg tcagtcttgg cgcgatgcgc
    20401 gtgttcgatc ttcgtcatcg cgcgaccggc gtcgtgcatg cgtaccggct gacgcacggc
    20461 agcctgctcg tgatgcgcgg ccgcacgcag gccgaatggc agcatcgcgt gccgaaggcg
    20521 ccggccgtgc agggcgagcg tatcaatctg acgttccggc gggtggtgtc ggcggcggcg
    20581 gggcgttagc cgctggccat gccgccggg
//
