LOCUS       NZ_CP066762            22853 bp    DNA     circular CON 30-NOV-2024
DEFINITION  Burkholderia ambifaria strain BJQ0010 chromosome 1, complete
            sequence.
ACCESSION   NZ_CP066762
VERSION     NZ_CP066762.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia ambifaria
  ORGANISM  Burkholderia ambifaria
            Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
            Burkholderiales; Burkholderiaceae; Burkholderia; Burkholderia
            cepacia complex.
REFERENCE   1  (bases 1 to 3480598)
  AUTHORS   Xu,Y.
  TITLE     Complete genome sequence of Burkholderia ambifaria BJQ0010
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3480598)
  AUTHORS   Xu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2020) School of Food and Chemical Engineering,
            Beijing Technology and Business University, No. 11, Fucheng Road,
            Haidian District, Beijing 100048, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016458785.1-RS_2024_11_30
            Annotation Date                   :: 11/30/2024 03:04:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,760
            CDSs (total)                      :: 5,675
            Genes (coding)                    :: 5,537
            CDSs (with protein)               :: 5,537
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 88 of 138
            Pseudo Genes (incomplete)         :: 78 of 138
            Pseudo Genes (internal stop)      :: 12 of 138
            Pseudo Genes (multiple problems)  :: 34 of 138
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:03:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2712172
            Orig. end                         :: 2735025
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066762.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22853
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="5"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22853
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22853
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12853](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12853)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(184..199)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    187..202
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.32"
                     /tool="antismash"
     misc_feature    complement(189..203)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(190..205)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.59"
                     /tool="antismash"
     misc_feature    193..208
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.47"
                     /tool="antismash"
     misc_feature    195..209
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.35"
                     /tool="antismash"
     misc_feature    199..214
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.37"
                     /tool="antismash"
     misc_feature    complement(201..214)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.07"
                     /tool="antismash"
     misc_feature    201..215
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    202..215
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.07"
                     /tool="antismash"
     misc_feature    204..218
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.64"
                     /tool="antismash"
     misc_feature    205..218
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.89"
                     /tool="antismash"
     gene            complement(220..1704)
                     /locus_tag="JG536_RS12535"
                     /old_locus_tag="JG536_12535"
     CDS             complement(220..1704)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01845.1"
                     /locus_tag="JG536_RS12535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12535"
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="WP_175656432.1"
                     /transl_table=11
                     /translation="MSIRLLLPFLLAAVFGGCASFPEERPPEIQVSEKWKFQGTAPAGD
                     TVETLDWIRAFGSHALVTMIEQCLQSSTTVVEADARLAAARAAMNDARSRLYPQLSFNG
                     ARTASGWLSSRGATGSGAAYTWTLSGAWDMDVWGEHRSSLRAAAYSVDAQRFAAIGARL
                     DLISAVTSSFVQLSALRERLGIANKNLASALRMQGLIASRVAKGYAMQLDLAQQDVLVS
                     TQRVAVASLDQQVGDSEIALARLLDVPPASMSVDVDSFEKLSIPDIGPGLPTQLLFRRP
                     DVSQSEASLLAADANLQAARAAVFPGFSLGASLSNPGSNLVALFTAPVYTVAASVVATV
                     FDGGHLQARREIAAAQKHVLLAEYRRSVVGAYADVESALNAVKQADDQATIQENAVRQA
                     RQVLALSIARHRAGGDTFLNVLDAQRLVFSQEDLAVQLRLSRLLAKVALFKSLGGGWSI
                     NGQLRTITNSGIPAALHTNGAADNVPMSESKRESSQ"
     misc_feature    complement(394..396)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1707..3647)
                     /locus_tag="JG536_RS12540"
                     /old_locus_tag="JG536_12540"
     CDS             complement(1707..3647)
                     /codon_start=1
                     /gene_functions="resistance (resist) macB"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024116.5"
                     /locus_tag="JG536_RS12540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12540"
                     /product="ABC transporter permease"
                     /protein_id="WP_175669609.1"
                     /transl_table=11
                     /translation="MTDVQKSFTGLSGPGNDDAAIVHAVRGVSLTIAAGEFVAIIGPSG
                     SGKSTLLHLMGGLDSPTAGEVFVGGREISRESADERAKIRREIVGFVFQSFNLLSGVNA
                     LANAALPGLYAGVDRSARRERADGLLRRLGMGERSMHLPSQLSGGQQQRAAIARALFNE
                     PAIILADEPTGALDSAMAAEVFELLRTLTRSGKTVVVVTHDRELALRTDRVIEVKDGAI
                     VSDCYLTARKRVECDPVARFEPSGVHPAIELGRSFCEMTRMAARVLWQTKFRSTLTLLG
                     IVIGVAAVISMLAVGSGAEEKVMKQMAAFGANRIYVVPGGENQRGPRATLKEVDIELIK
                     DVDNVQEAMPYLRDSGLVRFRNVSHRSEIAGVTTQYRRIFNWDVQSGSFFTDDDEQRLQ
                     PVAVIGQRLAVSLFGNHDPIGNYIIAKNVPLQVVGVLTEKGSIAGDDSADDILLLPFST
                     ASKRVIGKNEFSWISVKIDDISKAKQTVERISDVLERQHRIKDFQVYDATSAIQSQQET
                     QQVMTYMLAAIASISLIVGGIGVMNVLLVTVGERTKEIGVRMVCGARSVDIAAQFMCEG
                     LVLVAVGGTLGSVIGIAACYLLNALQIRTIPSAAAVVGAFGCAMLVGLASSVAPALKAA
                     RLDPVAALATE"
     misc_feature    complement(1719..1721)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(2889..2891)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3668..4840)
                     /locus_tag="JG536_RS12545"
                     /old_locus_tag="JG536_12545"
     CDS             complement(3668..4840)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020200582.1"
                     /locus_tag="JG536_RS12545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12545"
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_233410134.1"
                     /transl_table=11
                     /translation="MKNTKKTMIVGLALTTILLTSLGVFRTARPAPQQGVFRIQMGTVE
                     STVSALGTVLPATSVDVGAQVSGQILKIHVTINQEVKKGQLLVEIDPKLQQAKVDADRA
                     QLDSLNAQAADQLAQLRLTQLLLKRQQALALDGATRTEDIETAQANVDSSIAKVATLHA
                     QARGVESSLRGDEALLGYTKIYSPIDGAVLTLDVREGQTLNAVQQTPLLMRIADLTKMT
                     VWSEVSEADINLIKRGMKVRFSTLAAKAPNWTSTVRDVLSSPPNPPGQQANNPASQPPN
                     AKAVLYPVVFDVENLHGQLLPQMSAQVFFIVDAARNVTVVPLRFLTPVPGVMNTFTAGV
                     RVHGVVQTRTVVLGVRNRTLGQVVSGLAPGDELVHPGEGASTEGLGAARQ"
     misc_feature    complement(3872..3874)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4862..6037)
                     /locus_tag="JG536_RS12550"
                     /old_locus_tag="JG536_12550"
     CDS             complement(4862..6037)
                     /EC_number="1.14.11.47"
                     /GO_process="GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019619.5"
                     /locus_tag="JG536_RS12550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12550"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_105833094.1"
                     /transl_table=11
                     /translation="MNHHESLRHIDFGVDKATFLNFYYEKNILHRKGAFNADIVPLSEV
                     DSVLEHSDWNTNGFKLHDGREIALGSFTEDYDHLGLRRRRVDKKRFYELMRGGVSLVAN
                     SIDEHSRIVRSLCDEIAAFVEMPVVANGYLTFGDKNPFGNHWDTHDVFAVQLLGRKRWQ
                     LFKPTFPLPLVNQKSKFCKAECPKDPVLDVILEAGDFIYIPRGWWHNAQGLNERTFHLA
                     VGIHPPRMIDYVKWIAEQLLPSKLEARRGARCADEASGAVDELTAALSALVSDKENFRA
                     FTMDWASKERFKSSFDLSRYVEGGSESIECHHRIALNTVSHVELSDKTIVVNGKVNTIS
                     RIERDVIQMLNERGSMSVTELYEALELSPDDCREAVWALGVADVARILHDA"
     misc_feature    6038..6053
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 24.05"
                     /tool="antismash"
     misc_feature    complement(6069..6085)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            complement(6074..6805)
                     /locus_tag="JG536_RS12555"
                     /old_locus_tag="JG536_12555"
     CDS             complement(6074..6805)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="JG536_RS12555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12555"
                     /product="AAA family ATPase"
                     /protein_id="WP_175669608.1"
                     /transl_table=11
                     /translation="MLISATIKWGEVEDPCAYPFCLNSISEITSIDLRAKVTIFVGENG
                     AGKSTILEALAIALGCSAEGGSRNFRFSTANTHAPLHEYIRLARGPRRISDVFFYRAET
                     FYNFSTEMRRLDEADSFDPHIKTAYGGTDLHSLSHGQSVIQIFRHRFRAGGVYLLDEPE
                     AALSPARQIEVIAQAHRLTEAGAQIIMATHSPILMAIPGASIYEVSDDGLHSIAYDDLQ
                     QVSLYKRVLTDRESFIRGLLE"
     gene            complement(6799..8046)
                     /locus_tag="JG536_RS12560"
                     /old_locus_tag="JG536_12560"
     CDS             complement(6799..8046)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JG536_RS12560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JG536_12560"
                     /product="hypothetical protein"
                     /protein_id="WP_146125731.1"
                     /transl_table=11
                     /translation="MYMMSIPREMRLMAPLIVLVILATGYLIPLLPPYALRHVLDSVAT
                     QQVAHFWLLALALAYAGKIGSGIVVNVIQQWFIDCVARDKVRAILASSWIIHAAHERIH
                     QTVLSDIPKVARCSMLVVSIVGQMISLSTIGILISKFDYVVAVACYCPMLIVTGIFAYR
                     QHTTSLEFEAAQIADEAANGAALSIIKRKSNAWNAMSNRLALEKLAAILEQRASAKRCY
                     QLTRLFTTMLARLVLPLTSALTALVLLHAGKLDQVGSLAMVLAYLGSANMLCTGLLDNL
                     LEVRSTQVSFSRLRAVDYDAGPPAEVLDLDLEYKFCFKNIEEFAAMTGVVRSRMDAALV
                     AMDLSPTMLSRTNIDGTGLSNGENKRLYMAAAMSLSTAVLKVKGLRGYIDGTTYERLVE
                     NIGRYEQLTGKRVTLC"
     gene            complement(8037..9518)
                     /locus_tag="JG536_RS12565"
                     /old_locus_tag="JG536_12565"
     CDS             complement(8037..9518)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JG536_RS12565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JG536_12565"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146125732.1"
                     /transl_table=11
                     /translation="MNPNCDALAFALKHAGSGDRRRLCAIGVAVCVLSVIGSLAPLALA
                     NLVAIAGNVHGEVKWASLYGVAVIAPTVLGFALQKTLLYTLSRLVERIRVDCIAVAVRA
                     GKVPAATMSSGQLFSVVETDVERFDVVISALFVQVPQHITIVGSILLVVWLHQPAFGPW
                     IVLFAIVLLVFAVVPKSRVIALTAMARSARERCNGQLDLFLSHARLLTTVGCAERSIGT
                     VLHTIDAVRRTTLSANLFAQAAASTPQIALAMVTVGYLAAVVVGIGHSSIGLPYVLAVT
                     IYLEQALSPIASLALTSARLHASLPSLHHVTECFGRDTGAEAATASDAVCGRPHLKLRL
                     LSGATCETTLDSHKVWMAPNGAGKTTALMSITGMRESRDNQVFVENRVLSSRELESSTL
                     YFDSQALGIWHRLIAGQDNIDCMLNVVRECIKRGNTPLFVCFDETLDRIAKSPREVAEF
                     IEGLDTLGVVALVVTHNEQFRDCLISIGGEELRCT"
     misc_feature    complement(9420..9422)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9562..10011)
                     /locus_tag="JG536_RS12570"
                     /old_locus_tag="JG536_12570"
     CDS             complement(9562..10011)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JG536_RS12570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JG536_12570"
                     /product="hypothetical protein"
                     /protein_id="WP_105833098.1"
                     /transl_table=11
                     /translation="MPTDWNQVRSLIGAAIDACETYENLEPKEEDREIELSVGEVKVFE
                     LVTSAYTFAENTRYSIIRTRHRGGFDNRYVPEAARILRAVTHAAIELIGAAPGMTNGRA
                     SPSLQEKESRQELKTQVDAMISWYRDFFAVELRRALEKRAKPVLN"
     gene            complement(10001..12853)
                     /gene="lanM"
                     /locus_tag="JG536_RS12575"
                     /old_locus_tag="JG536_12575"
     CDS             complement(10001..12853)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="JG536_RS12575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12575"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_233410135.1"
                     /sec_met_domain="DUF4135 (E-value: 1.2e-58, bitscore:
                     196.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-29, bitscore:
                     100.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRDIVAAFLTNLANRLDVFARQAILFEKKLHQALTGSNSISYSD
                     FVSLLSNDPSRVVNLLSQYPGLEQLLSTITTNFCNNAFEFAVALEADYEEIQTRFEMPS
                     TLEGRSINIELTDGELHCSSRSIVIVSIDGRNTFGYKPRNLDAEAQLTALLQEFSSDLG
                     FHSDWTLPQYVLGESHGWVKWVDYREAPDEASIRRFYTRAGYLIGFSELYGISDLHNGN
                     LIAHGDSPVPVDMEAALTPQIGSDGVEEIGTYGAWNLLGTGLLPSATWKGGDLVGIDTS
                     GLGGLNSQYCSMAVYQNTGKGRLDEAFSDAGTTIEPSLNVLRFRGEIQKPWNYLDELEA
                     GYRVALTTIPRKPRAIVALGQLAATEMRYIHQSTAGYHFALQASVHPCLLTDVHQRRDY
                     LRSCLSATSSENRSLLEAEVLACEGGDVPRFVGHPDGIEVREPAYLAYPTQIPGASLSG
                     IQNSAQMVTSVSEARIAFGVRLLRGSMKALEIHFANGAGYRSSLLIPPKTSASDGEPRA
                     TEALCDFGAAARESLEATQRYVERQEAANGDRKRLEWYGCKTSPSGGMEFGQVGTDLYH
                     GSSGILMAMQLLGRGDAGDLVARATRTAISELDREITKLGGSYIGLSSAILPLYAMSSK
                     VSHPLAAELTAAAKDKFARAVASRHPMQYFVGSDLICGVAGALNVAALMYSTTADTEWR
                     SLAEGISTILLAQVRETDGAFLIPNGKSVSVEEDGCLTGLSHGQIGIALALSNYARRCE
                     PAPAHKGRIEELVNSLTRWELSKYCVREANWPDYRVRSAAENVQPFEFGWSHGGPGIYL
                     ALMELAASNHAARQFTEAVPYLTIIEAALGRRRSPVNVTICHGSLGAVNLSRRLLAMQE
                     DVATVAACMDELIAWSRLSEFVQMDKEEFNLGDFDMPGLWTGRAGAALGYACLENDALS
                     VPFLIDDIVKLFNLERQHAH"
     misc_feature    complement(10067..10069)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10412..10414)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12887..12902)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.68"
                     /tool="antismash"
     CDS             complement(12954..13088)
                     /gene="allorf_2725126_2725260"
                     /locus_tag="allorf_2725126_2725260"
                     /protein_id="allorf_2725126_2725260"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSWAIRNTIPRLGSGIGAIANCAIKKRRLADERKHSEILYVPGR"
     CDS_motif       complement(13035..13088)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSWAIRNTIPRLGSGIGA"
                     /locus_tag="allorf_2725126_2725260_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12954..13034)
                     /prepeptide="core"
                     /locus_tag="allorf_2725126_2725260_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="3019.5"
                     /monoisotopic_mass="3017.7"
                     /core_sequence="IANCAIKKRRLADERKHSEILYVPGR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSWAIRNTIPRLGSGIGA"
                     /leader_location="[13034:13088](-)"
     CDS             13200..13424
                     /gene="allorf_2725372_2725596"
                     /locus_tag="allorf_2725372_2725596"
                     /protein_id="allorf_2725372_2725596"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWYFKNEAISSGSLMETRSISSATFRAAAYAAKLIEVPEGLFCRL
                     RIGELLVWRFIADTKSGPLLLCHMHIEDF"
     CDS_motif       13200..13295
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MWYFKNEAISSGSLMETRSISSATFRAAAYAA"
                     /locus_tag="allorf_2725372_2725596_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13296..13424
                     /prepeptide="core"
                     /locus_tag="allorf_2725372_2725596_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="4873.8"
                     /monoisotopic_mass="4870.6"
                     /core_sequence="KLIEVPEGLFCRLRIGELLVWRFIADTKSGPLLLCHMHIEDF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWYFKNEAISSGSLMETRSISSATFRAAAYAA"
                     /leader_location="[13199:13295](+)"
     misc_feature    13393..13403
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     CDS             complement(13456..13608)
                     /gene="allorf_2725628_2725780"
                     /locus_tag="allorf_2725628_2725780"
                     /protein_id="allorf_2725628_2725780"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKTPSRKKWQKTHVPVHVATSKRWRYTETAARNAGATTRTSSITC
                     SYKGL"
     CDS_motif       complement(13504..13608)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKTPSRKKWQKTHVPVHVATSKRWRYTETAARNAG"
                     /locus_tag="allorf_2725628_2725780_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13456..13503)
                     /prepeptide="core"
                     /locus_tag="allorf_2725628_2725780_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="1462.6"
                     /monoisotopic_mass="1461.8"
                     /core_sequence="ATTRTSSITCSYKGL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKTPSRKKWQKTHVPVHVATSKRWRYTETAARNAG"
                     /leader_location="[13503:13608](-)"
                     /alternative_weights="1480.7"
                     /alternative_weights="1498.7"
                     /alternative_weights="1516.7"
                     /alternative_weights="1534.7"
                     /alternative_weights="1552.7"
                     /alternative_weights="1570.8"
     CDS             complement(13487..13585)
                     /gene="allorf_2725659_2725757"
                     /locus_tag="allorf_2725659_2725757"
                     /protein_id="allorf_2725659_2725757"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAENSRTCTCGYVEALAIYGNRGSQCGCHYKN"
     CDS_motif       complement(13523..13585)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAENSRTCTCGYVEALAIYGN"
                     /locus_tag="allorf_2725659_2725757_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13487..13522)
                     /prepeptide="core"
                     /locus_tag="allorf_2725659_2725757_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.30"
                     /molecular_weight="1234.4"
                     /monoisotopic_mass="1233.5"
                     /core_sequence="RGSQCGCHYKN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAENSRTCTCGYVEALAIYGN"
                     /leader_location="[13522:13585](-)"
     misc_feature    13501..13514
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            13608..14009
                     /locus_tag="JG536_RS12580"
                     /old_locus_tag="JG536_12580"
     CDS             13608..14009
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JG536_RS12580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JG536_12580"
                     /product="hypothetical protein"
                     /protein_id="WP_146125734.1"
                     /transl_table=11
                     /translation="MSELPSTDWGQIRDVLAAAVNFCEQLEALGYSENSRTRSALVNGT
                     NVSAFEVVTSAWTLAEATRYTVIRSRHDANNDLSYVPEAARILAAASSVCAELVHSGGK
                     VDANVAIERLKTWLNTEGVEALKTTLGEP"
     gene            14212..14379
                     /locus_tag="JG536_RS12585"
                     /old_locus_tag="JG536_12585"
     CDS             14212..14379
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006750029.1"
                     /locus_tag="JG536_RS12585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12585"
                     /product="hypothetical protein"
                     /protein_id="WP_175656428.1"
                     /transl_table=11
                     /translation="MSMRTTSCALCRGALAVVLALTLGGCDVLTAPPVPDWPGPHAPYP
                     FPDNIPHRAE"
     gene            complement(14404..15306)
                     /locus_tag="JG536_RS12590"
                     /old_locus_tag="JG536_12590"
     CDS             complement(14404..15306)
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012364495.1"
                     /locus_tag="JG536_RS12590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12590"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_175669607.1"
                     /transl_table=11
                     /translation="MAFDSRLLSGIGVLSAVIEAGTFARAGEAMGLTQPAVSRAVARLE
                     ERVGIRIFNRTARAITLTDEGRRFYEAVAPLLAGIEEAAVDAGRSRARVRGRLRVNVDG
                     TFGHYVLAPRMVEFLDRFPELSVEISVRDRMGDLVADGFDVAVRFGIPEPSSYRARLLL
                     ETHVLTCASAAYVARHGEPRHPRDLADGHRCVLIRDPVTGRPYGWEFHRGDEVVPFDAT
                     GRLTVNDTGALLGACVGGEGVAQLLELYARDILAEGRLVQLLPEWADETFPLYAYHHAS
                     NLVSAKVRVFLDFVRELTG"
     gene            15424..16161
                     /locus_tag="JG536_RS12595"
                     /old_locus_tag="JG536_12595"
     CDS             15424..16161
                     /NRPS_PKS="Domain: PKS_KR (6-180). E-value: 6.7e-17. Score:
                     53.9. Matches aSDomain:
                     nrpspksdomains_JG536_RS12595_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011545991.1"
                     /locus_tag="JG536_RS12595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12595"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_175669606.1"
                     /sec_met_domain="adh_short (E-value: 5.2e-38, bitscore:
                     128.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.5e-32, bitscore:
                     111.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSKQVALVTGSSRGIGAEIARRLARDGFRVVVNYAGGAGPARE
                     VVEAIAANGGEAIAVQADIADPVAVAALFDAAEQAFGHIDVVVNSAGVMKLGAIADYDD
                     TTFDQTVAINLKGTFNVSREAAKRVRSGGRIVNLSSTMVGVRLPTYGVYVATKAAVEGL
                     TQVLAQEMRGRGISVNAVAPGPVATELFLQGKSPEQVDRLAKMNPLERLGQPADIAGVV
                     AFLAGPDGAWVNGQILRANGGMC"
     aSDomain        15442..15963
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JG536_RS12595_PKS_KR.1"
                     /evalue="6.70E-17"
                     /label="JG536_RS12595_PKS_KR.1"
                     /locus_tag="JG536_RS12595"
                     /protein_end="180"
                     /protein_start="6"
                     /score="53.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGSSRGIGAEIARRLARDGFRVVVNYAGGAGPAREVVEAIA
                     ANGGEAIAVQADIADPVAVAALFDAAEQAFGHIDVVVNSAGVMKLGAIADYDDTTFDQT
                     VAINLKGTFNVSREAAKRVRSGGRIVNLSSTMVGVRLPTYGVYVATKAAVEGLTQVLAQ
                     EMRGRGISVNA"
     CDS_motif       15448..15588
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JG536_RS12595_0001"
                     /evalue="1.20E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="JG536_RS12595"
                     /protein_end="55"
                     /protein_start="8"
                     /score="14.7"
                     /tool="antismash"
                     /translation="LVTGSSRGIGAEIARRLARDGFRVVVNYAGGAGPAREVVEAIAAN
                     GG"
     gene            16236..17135
                     /locus_tag="JG536_RS12600"
                     /old_locus_tag="JG536_12600"
     CDS             16236..17135
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-173). E-value: 9.2e-17. Score:
                     53.5. Matches aSDomain:
                     nrpspksdomains_JG536_RS12600_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006750032.1"
                     /locus_tag="JG536_RS12600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12600"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_175660282.1"
                     /sec_met_domain="adh_short (E-value: 3.7e-31, bitscore:
                     106.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEVILVTGASSGFGLLTAQALARAGHTVYASMRESAGRNAPRVA
                     AIADYAREHGVDLRTVELDVGDDASVAAAIERVIADNGRLDVVVHNAGHMVFGPAEAFT
                     PDQLAQLYDINVVSTQRVNRAVLPHLRSRGRGLLVWVSSSSARGGTPPFLAPYFAAKAA
                     MDSLAVSYAAELARWGIETSIVVPGAFTHGTNHFAHAGKPADTAVQAAYDDGPYARVAE
                     QALQGLAALEPADADAATVATAIVDIVAAPSGKRPYRVFVDPSQDGAEEVFRVGDRIRR
                     EMFRNIGLADLLTPRVGN"
     aSDomain        16245..16754
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JG536_RS12600_PKS_KR.1"
                     /evalue="9.20E-17"
                     /label="JG536_RS12600_PKS_KR.1"
                     /locus_tag="JG536_RS12600"
                     /protein_end="173"
                     /protein_start="3"
                     /score="53.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VILVTGASSGFGLLTAQALARAGHTVYASMRESAGRNAPRVAAIA
                     DYAREHGVDLRTVELDVGDDASVAAAIERVIADNGRLDVVVHNAGHMVFGPAEAFTPDQ
                     LAQLYDINVVSTQRVNRAVLPHLRSRGRGLLVWVSSSSARGGTPPFLAPYFAAKAAMDS
                     LAVSYAA"
     CDS_motif       16248..16313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JG536_RS12600_0001"
                     /evalue="7.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="JG536_RS12600"
                     /protein_end="26"
                     /protein_start="4"
                     /score="15.5"
                     /tool="antismash"
                     /translation="ILVTGASSGFGLLTAQALARAG"
     gene            complement(17167..18057)
                     /locus_tag="JG536_RS12605"
                     /old_locus_tag="JG536_12605"
     CDS             complement(17167..18057)
                     /NRPS_PKS="Domain: Abhydrolase_1 (27-281). E-value:
                     2.1e-24. Score: 78.4. Matches aSDomain:
                     nrpspksdomains_JG536_RS12605_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011657692.1"
                     /locus_tag="JG536_RS12605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12605"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_175669605.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.9e-16, bitscore:
                     58.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.3e-17, bitscore: 61.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAYRFAATASLELAYLEWNPRAERVAVLLHGWPDSPVGWETVAQ
                     ALAVRGYRVLAPALRGFAPTRFRDTTVPRSGQLAALGRDLLEFVDVLGLERPVLVGHDW
                     GARAVANACGLRDGVASHLVMLSVGYGTNDPAQPLSLQQARNYWYHWFMATPRGEQALR
                     DDRRAFARLMWDTWSPPGWYREAEFEAAATAFDGPDWIDVVLHSYRQRWGFAPGTPAYA
                     DDDARLNPAPRLSVPTLVLHGGADACNHPDGSAGRERFFTGRYARQVLDGVGHFPQREA
                     PAAVAEAILGFCERD"
     aSDomain        complement(17215..17976)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JG536_RS12605_Abhydrolase_1.1"
                     /evalue="2.10E-24"
                     /label="JG536_RS12605_Abhydrolase_1.1"
                     /locus_tag="JG536_RS12605"
                     /protein_end="281"
                     /protein_start="27"
                     /score="78.4"
                     /tool="antismash"
                     /translation="VLLHGWPDSPVGWETVAQALAVRGYRVLAPALRGFAPTRFRDTTV
                     PRSGQLAALGRDLLEFVDVLGLERPVLVGHDWGARAVANACGLRDGVASHLVMLSVGYG
                     TNDPAQPLSLQQARNYWYHWFMATPRGEQALRDDRRAFARLMWDTWSPPGWYREAEFEA
                     AATAFDGPDWIDVVLHSYRQRWGFAPGTPAYADDDARLNPAPRLSVPTLVLHGGADACN
                     HPDGSAGRERFFTGRYARQVLDGVGHFPQREA"
     gene            18163..19059
                     /locus_tag="JG536_RS12610"
                     /old_locus_tag="JG536_12610"
     CDS             18163..19059
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006482775.1"
                     /locus_tag="JG536_RS12610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12610"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_175669604.1"
                     /transl_table=11
                     /translation="MEPPIDRASTALDITLLRTFLEVVDSRGFAPAAERLALTPSAVSG
                     HIKRLEQAAGTVLLARTTRRVALTPAGDTLYAYARNIVDMEREVRARLRGAPAHGRLRV
                     GASEDFAGTWLPQVLRTFRDNHPRTSIELKVGITASLLREQALGRLDVVFGKQCRQVDA
                     PGELLWEEPLVWAFASDTALNAEGDVPLALFPEPCVYREAAVAALAAALRPFRVLFESG
                     SMAGCVSAALAGFAVTALARSQLRDGLRACGPDDGLPALPAARFHAFASKPDGAAAALI
                     DAVRATGRSRQFAARFD"
     gene            complement(19138..20067)
                     /locus_tag="JG536_RS12615"
                     /old_locus_tag="JG536_12615"
     CDS             complement(19138..20067)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011694365.1"
                     /locus_tag="JG536_RS12615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12615"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_126228353.1"
                     /transl_table=11
                     /translation="MDKLDQVRIFLQVAEMGSFIKAAHALDVPRATVSAAVQQLEAALG
                     TRLLHRTTRQVQLTADGALLLERGRRLLAEADELDRLFRRRDRDVVGRLNVDAPSRIAR
                     RVIAPALPSLFRRHPKLQLSLGSTDRTIDLVQEGVDCAIRVGRLADSSLVVRPLGQFTL
                     INCASPDYLRECGVPEHPDALAHGHWAIGYASPTTGRELGWEYCADGGQHTLALPSRVI
                     VNNAETYIASCIAGMGLIQIPRFDVAHLLDSGALVEVMPGHRAAPMDVSAVYPHRRHRS
                     RRLNAFIEWFGELMADALSDTGVAARGD"
     misc_feature    complement(20074..20087)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            complement(20243..21016)
                     /locus_tag="JG536_RS12620"
                     /old_locus_tag="JG536_12620"
     CDS             complement(20243..21016)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-172). E-value: 8.1e-14. Score:
                     43.9. Matches aSDomain:
                     nrpspksdomains_JG536_RS12620_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010090962.1"
                     /locus_tag="JG536_RS12620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12620"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_011657695.1"
                     /transl_table=11
                     /translation="MATHTLADKVVLIAGGAKNLGGLIARDLAGHGAKAVAIHYNSAAS
                     QAQAEETAAAVRAAGAQAATFQADLTTAAAVEKLFDDAKQRFGKIDIAINTVGKVLKKP
                     FTDISEAEYDEMFAVNSKSAFFFIKEAGRHLEDHGKLVTLVTSLLGAFTPFYAAYEGSK
                     APVEHFTRAASKEYGARGISVTAVGPGPMDTPFFYPAEGADAVAYHKTAAALSPFSKTG
                     LTDIEDVVPFIRHLVTDGWWITGQTILINGGYTTK"
     aSDomain        complement(20501..20989)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JG536_RS12620_PKS_KR.1"
                     /evalue="8.10E-14"
                     /label="JG536_RS12620_PKS_KR.1"
                     /locus_tag="JG536_RS12620"
                     /protein_end="172"
                     /protein_start="9"
                     /score="43.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLIAGGAKNLGGLIARDLAGHGAKAVAIHYNSAASQAQAEETAA
                     AVRAAGAQAATFQADLTTAAAVEKLFDDAKQRFGKIDIAINTVGKVLKKPFTDISEAEY
                     DEMFAVNSKSAFFFIKEAGRHLEDHGKLVTLVTSLLGAFTPFYAAYEGSKAPVEHFTRA
                     "
     CDS_motif       complement(20906..20989)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JG536_RS12620_0001"
                     /evalue="3.20E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="JG536_RS12620"
                     /protein_end="37"
                     /protein_start="9"
                     /score="19.8"
                     /tool="antismash"
                     /translation="VVLIAGGAKNLGGLIARDLAGHGAKAVA"
     CDS             21093..21314
                     /gene="allorf_2733265_2733486"
                     /locus_tag="allorf_2733265_2733486"
                     /protein_id="allorf_2733265_2733486"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNYPEKRSNHSAGMVGCRTDGGYSICPTRHDGGGLPAARQRIECH
                     GLSVKNGRAQRSGSSPARARSCRRRHAA"
     CDS_motif       21093..21134
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNYPEKRSNHSAGM"
                     /locus_tag="allorf_2733265_2733486_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21135..21314
                     /prepeptide="core"
                     /locus_tag="allorf_2733265_2733486_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="6114.8"
                     /monoisotopic_mass="6111.1"
                     /core_sequence="VGCRTDGGYSICPTRHDGGGLPAARQRIECHGLSVKNGRAQRS
                     GSSPARARSCRRRHAA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNYPEKRSNHSAGM"
                     /leader_location="[21092:21134](+)"
                     /alternative_weights="6132.8"
                     /alternative_weights="6150.8"
                     /alternative_weights="6168.9"
                     /alternative_weights="6186.9"
     misc_feature    21097..21111
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.15"
                     /tool="antismash"
     gene            21330..22046
                     /locus_tag="JG536_RS12625"
                     /old_locus_tag="JG536_12625"
     CDS             21330..22046
                     /EC_number="5.4.99.-"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154: Pseudouridine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014896298.1"
                     /locus_tag="JG536_RS12625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12625"
                     /product="pseudouridine synthase"
                     /protein_id="WP_175669603.1"
                     /transl_table=11
                     /translation="MDLESILYTQGFGSRRQCRGLIETGRVTVAGASATDPDASFDTDG
                     LVFTVDGTAWPFHARAYLALNKPAGYECSRDPQHHASVFSLLPAPLVARGVQCVGRLDQ
                     DTTGLLLLSDDGQFVHAYTSPKRKVPKTYVATVRHPLDDTQLNALRAGVQLHGEPKPIA
                     AVAAHARDTHALALTVLEGKYHQVKRMVAAASNRVEALHRESIGGFTLPEDLAPGAWRW
                     LGEGDLSALRDPVKTL"
     gene            22153..22341
                     /locus_tag="JG536_RS12630"
                     /old_locus_tag="JG536_12630"
     CDS             22153..22341
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011546000.1"
                     /locus_tag="JG536_RS12630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JG536_12630"
                     /product="hypothetical protein"
                     /protein_id="WP_011657697.1"
                     /transl_table=11
                     /translation="MNINHSLELSYVMIAFAVMGVIVIGALLAMMHRKHKYSPNLIGAL
                     IGALLCFLLIEALPALT"
     CDS_motif       22153..22203
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNINHSLELSYVMIAFA"
                     /locus_tag="JG536_RS12630_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22204..22341
                     /prepeptide="core"
                     /locus_tag="JG536_RS12630_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="4750.9"
                     /monoisotopic_mass="4747.7"
                     /core_sequence="VMGVIVIGALLAMMHRKHKYSPNLIGALIGALLCFLLIEALPA
                     LT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNINHSLELSYVMIAFA"
                     /leader_location="[22152:22203](+)"
                     /alternative_weights="4768.9"
ORIGIN
        1 taaatacatg cgacgcgccg aatcctcaag aggaaggcta aacccaccaa gtctaggctc
       61 aatattccat tttgaattca tttcaccccc acaccccttt ttattctacg cggaatggca
      121 tatcgctcac cacatttcac acaccacagc aaacaaatct tattgttcct ctggcacgat
      181 gtcaataata aaaatcaatc tcattatcat tatcaaaatc tattgactcg actcgcgctt
      241 cgactcgctc ataggtacat tatcggcggc accattagtg tgtagcgccg cagggatacc
      301 actattcgta atagttcgaa gttgcccatt gatactccat cccccgccca aagacttgaa
      361 caatgccact tttgccagca accgcgacag gcgtaactgc accgctagat cctcttggga
      421 aaacaccaaa cgttgagcgt cgagtacatt gaggaaggta tccccaccgg cgcggtgacg
      481 cgcgatggat agagccagca cctgccttgc ctgacgaacc gcattctctt ggattgtggc
      541 ctgatcgtca gcttgcttca cggcgttcaa tgccgactcg acgtcggcgt aagcaccgac
      601 gacagaccgc cggtattcgg caagcaacac gtgcttctga gccgcggcaa tttctcgccg
      661 cgcttggaga tgtccgccgt cgaacactgt cgccacgact gaagccgcaa cggtatagac
      721 aggtgccgtg aagagggcta cgaggttcga cccgggattg ctcagcgatg ccccgagact
      781 gaagccggga aacactgctg cacgagctgc ctgaagattc gcgtccgccg ccagcagaga
      841 agcctccgat tgggaaacat ccggacgtct aaacaggagt tgagttggca gccctggccc
      901 gatgtctggt atcgagagct tttcgaacga atcgacgtca accgacatgg acgccggcgg
      961 cacgtccaac aatctggcta gcgcgatctc cgaatctcct acctgttgat cgagcgacgc
     1021 tacggcgact ctctgagtcg agacgaggac gtcctgttgc gccagatcga gctgcatcgc
     1081 atatcctttc gcgacgcgac tggcaatgag cccctgcatc ctcagggccg atgccaggtt
     1141 tttgttggcg ataccgagac gttcgcgcag tgcgctgagc tggacaaacg acgacgtgac
     1201 tgccgagatg agatcaagtc gcgcgccaat tgcagcaaag cgctgagcgt cgaccgaata
     1261 cgctgcggcg cgcagcgagg agcggtgttc tccccacacg tccatgtccc atgcgcccga
     1321 aagcgtccaa gtgtaagccg cgcccgaccc cgtcgcgcca cgacttgaaa gccagccgga
     1381 cgcagttcga gcaccgttga aggaaagctg cggatagagt cggctccttg catcgttcat
     1441 ggccgcacgc gctgccgcca gtcgggcatc agcctcgaca acggtcgtgc tgctttgcag
     1501 acattgctcg atcatcgtga cgagggcgtg gctcccaaat gcccgaatcc aatccagagt
     1561 ttcgacggta tcgcccgctg gtgccgtgcc ttgaaatttc catttttccg aaacctgaat
     1621 ctccggtggc cgctcttcgg ggaacgatgc gcagccaccg aagaccgccg ccagcaaaaa
     1681 cggtagaagt agacgtatgc tcatggctat tccgtcgcta atgcggccac cggatcaagt
     1741 cgtgcagcct tcaacgccgg cgcgaccgac gacgcgagtc cgacgagcat cgcgcaaccg
     1801 aaagccccca ccaccgcggc tgctgacgga atggttctga tctgcagcgc gttcaacaga
     1861 tagcacgcgg caataccgat cacactcccg agcgtcccgc ccaccgctac gagcaccaag
     1921 ccttcgcaca taaactgagc ggcaatatcg accgaacgtg cgccgcatac cattcgcacc
     1981 ccgatttcct tcgtgcgctc acccaccgtc acgagcaata cgttcatcac accgattcca
     2041 ccaacaatga gcgaaatcga cgcgatcgcc gcgagcatgt atgtcatcac ttgctgcgtt
     2101 tcctgctggg attgaattgc tgatgtcgcg tcgtagacct gaaagtcctt gattcggtgt
     2161 tgccgctcga gaacgtcgct gatccgttca accgtctgtt tcgccttgga gatgtcgtcg
     2221 atcttgaccg atatccacga aaattcgttt ttgcctatta cgcgcttgct cgctgtcgag
     2281 aacggcaaca acagaatatc gtcggccgaa tcgtcgccgg caatggaccc tttctcggtc
     2341 agcacgccga cgacctgcag cggcacgttc ttcgcgataa tgtagttgcc gatcggatcg
     2401 tgatttccaa acaggctcac ggcaagccgt tgcccgataa cggcgacagg ctgcaacctc
     2461 tgttcgtcat cgtccgtaaa aaagctgccg ctctggacgt cccagttgaa tattctccga
     2521 tattgagtcg tgacccctgc tatctcgctt cgatgactca cgtttctgaa gcgcacgagt
     2581 ccgctatctc gaagataggg catggcttcc tgaacgttgt cgacatcctt gatcaattca
     2641 atgtcgactt ccttcaacgt tgcgcgcggt ccgcgctgat tctctccgcc ggggacgacg
     2701 tagatcctgt tcgcaccgaa cgcagccatc tgcttcatca ctttttcttc ggcgccgctt
     2761 ccgaccgcca gcatcgaaat tacggcggca acgccgatca cgatccctag cagcgtaagg
     2821 gttgaccgaa acttcgtttg ccagagcacg cgcgccgcca tcctcgtcat ctcgcagaac
     2881 gaccgcccta actcgatcgc cggatgcacg ccggatggct cgaaccgggc caccggatcg
     2941 cattccacgc gtttccgggc ggtcagatag caatccgata cgatcgcccc gtccttgacc
     3001 tcgattacgc ggtcggtacg caacgccagc tcccggtcat gcgttactac gacgacggtt
     3061 tttccggagc gcgtgagggt ccgcaacagt tcgaagacct ccgccgccat cgccgaatca
     3121 agcgcgccag ttggctcgtc ggcgaggatg atggcgggct cgttgaacaa cgctctcgcg
     3181 atcgcggccc gctgctgctg cccgccggaa agctgcgacg gcaaatgcat gctccgttcg
     3241 cccataccga gcctccgcag cagtccgtct gcacgttcac ggcgagcact gcgatccacg
     3301 ccagcataca aaccgggcaa cgccgcgttt gcgagcgcgt tgacgcccga aagcaggtta
     3361 aacgactgga acacgaatcc gacaatttca cgccggattt tggcccgttc gtctgccgac
     3421 tcgcgggata tctcgcgtcc accaacaaag acctcgcccg ctgtcggcga gtccaatccc
     3481 cccatcaaat gcagcagcgt tgattttccg gaaccagaag gcccgatgat tgcaacgaac
     3541 tctcctgccg caatcgtcag cgagactcca cgcacggcgt gcacgatcgc cgcatcgtcg
     3601 ttccctggtc cgctcaaacc ggtgaagctc ttctgaacat ccgtcaaaac aagcgcgttt
     3661 accgtcctca ttggcgagcc gctcccaatc cctccgttga cgcgccttcc ccgggatgca
     3721 cgagctcgtc acccggggca agccccgata cgacttggcc gagcgtccgg tttcgtacgc
     3781 cgagcacaac cgtacgcgtc tgaaccacac catggacccg cacaccggca gtgaacgtgt
     3841 tcatgacacc cggcaccggt gtgaggaacc gtaaaggaac gactgtcacg ttgcgcgcgg
     3901 catccacgat gaagaacact tgagcggaca tctgcggtag caactgccca tgcaggttct
     3961 ccacatcgaa gaccacggga tagagcaccg ccttcgcgtt gggcggctgc gacgcgggat
     4021 tgttcgcctg ctgacccggc gggttcggcg gcgacgaaag aacgtcacgc accgtgctcg
     4081 tccagttcgg cgccttcgcg gccagtgtcg agaaccgtac cttcatgcca cgcttgatca
     4141 gattgatgtc ggcctccgac acttccgacc agaccgtcat ctttgtcaag tcggcgatcc
     4201 gcatcagcag cggcgtctgc tgcaccgcat tcaaggtttg gccctccctg acgtccaagg
     4261 taaggacagc cccatcgatt ggcgaataga tcttcgtata acccagcaat gcctcgtcgc
     4321 cacgcaacga cgactcgaca cccctcgcct gagcgtgaag ggtggcgacc ttcgcgatgc
     4381 tcgaatcgac gttggcttgc gccgtttcga tgtcttcggt ccgcgttgcg ccgtcaagtg
     4441 caagcgcttg ctggcgcttc aacagcagtt gcgtcaagcg caattgcgcc agttgatcgg
     4501 cagcctgagc gttgagcgag tccaactggg cacgatcggc atcgaccttc gcttgctgca
     4561 acttcggatc gatctcgacg agaagctggc ctttcttcac ttcctggttg atcgtcacat
     4621 gtatcttgag aatctgcccc gaaacctgag caccaacgtc taccgacgtt gcgggcagga
     4681 ccgtgccaag cgcggacacg gttgactcga cggtgcccat ctggatcctg aacacccctt
     4741 gctggggtgc cgggcgtgcg gtccggaaga cgcccagaga cgtcagcagg atcgtggtca
     4801 acgccaagcc aacgatcatc gtttttttcg tgttcttcaa agactgcatc gtcctttcgc
     4861 actacgcgtc gtgcaagatg cgcgcgacat ccgcgacacc aagcgcccac accgcttccc
     4921 ggcaatcgtc cggcgagagt tcaagcgcct cgtaaagctc cgtcacgctc atcgatccac
     4981 gctcattcag catctgaatg acgtctcgct cgatgcgact gatcgtgttg accttcccgt
     5041 ttacaactat cgtcttgtca gacaattcca cgtgcgacac cgtattcaac gcgatccgat
     5101 ggtggcactc gatcgattca cttccgcctt cgacatacct cgacaaatcg aaactcgact
     5161 tgaagcgctc cttcgacgcc cagtccatcg tgaaagcacg gaaattctct ttgtccgaga
     5221 cgagcgcgct gagtgccgcc gtcaactcat cgacggcgcc ggaagcttcg tctgcacacc
     5281 gcgccccgcg ccgggcctcg agttttgatg gcagcagctg ctcggcaatc catttgacat
     5341 agtcgatcat ccgaggagga tggattccga cggccagatg aaatgtgcgc tcattgagac
     5401 cctgcgcgtt gtgccaccat ccccgcggga tgtagatgaa gtcccccgcc tccaggatca
     5461 cgtcgagaac ggggtccttt gggcactccg ctttgcagaa cttgctcttt tggttcacca
     5521 gcggcagcgg gaacgtcggc ttaaacagct gccagcgctt gcggccgaga agctgaacgg
     5581 caaagacatc gtgcgtatcc caatggttac caaacggatt cttgtccccg aaagtcaggt
     5641 aaccgttcgc aaccaccggc atttccacga acgcagcaat ctcgtcgcaa agcgaccgaa
     5701 caatccgcga atgctcatcg atgctgtttg cgacgagcga aacccctccg cgcatcaact
     5761 cgtagaacct ttttttgtcg acacggcggc ggcgaaggcc gaggtgatcg tagtcttcgg
     5821 tgaaggagcc gagtgcaatt tcccgcccat catggagttt gaagccattc gtattccaat
     5881 ccgagtgctc cagcacgcta tccacttccg acaatggaac aatatctgcg ttgaatgccc
     5941 ctttgcgatg gagaatattt ttctcgtaat agaaatttag gaatgttgcc ttgtcgacac
     6001 cgaaatcgat atggcgaagc gattcgtgat ggttcatgtt cacccttgta aactaatcgg
     6061 tatgtgaaat gttttattcg agcaagccgc gtataaaact ctcccggtcc gtaaggaccc
     6121 gcttatagag tgagacttgc tgcagatcgt cgtacgcaat gctgtggagt ccgtcgtccg
     6181 atacctcgta tatcgacgcg ccggggatcg ccatcaagat cggcgaatgt gtcgccatga
     6241 tgatttgcgc ccccgcctca gtcagtctat gcgcctgcgc gatcacctcg atttggcgcg
     6301 cgggagacag cgcagcttcg ggttcgtcga gcaggtacac gccgccggcg cggaaccgat
     6361 ggcgaaagat ctgtatgaca gactggccat gcgatagcga gtggagatcg gtcccgccat
     6421 aggccgtctt gatgtgtgga tcgaagctgt cggcctcgtc cagccgccgc atttcagtcg
     6481 agaagttgta gaacgtctcg gcccggtaaa agaaaacgtc gctgattcgc cgcggccctc
     6541 tggcgagcct gatgtactcg tgcagcggcg cgtgcgtatt ggccgtcgag aagcggaaat
     6601 tccgtgaacc accctcggcg ctacagccga gcgcgatcgc cagcgcctcc aggatcgtcg
     6661 actttcccgc gccgttttcc ccgacgaaga tcgtcacttt cgcacgcagg tcgatcgaag
     6721 ttatttcgct gatggaattc agacaaaatg gatacgcgca ggggtcttcc acttcccccc
     6781 atttgatcgt tgcggaaatc agcatagcgt cactcgctta cccgtgagtt gttcgtagcg
     6841 gccaatgttc tccaccaacc gttcatatgt cgttccatct atatagccac gcagtccctt
     6901 cactttgaga acggcagtcg agagactcat cgccgcagcc atgtagagcc gcttgttctc
     6961 cccattggaa aggcccgtcc cgtcgatatt ggttcgggac agcatggtgg gcgacagatc
     7021 catggccacc aacgcggcat ccatccgaga ccgaaccacg cccgtcatcg cagcaaattc
     7081 ttcgatgttc ttgaagcaga acttgtattc cagatcgaga tccagcacct cggccggggg
     7141 gccggcatcg tagtcgaccg ctcgaagcct cgagaacgaa acctgcgttg atctgacttc
     7201 caggagattg tcgagcaggc ccgtgcagag catgttggcg cttcccagat aagccaacac
     7261 catcgcgagc gaaccgactt gatcgagctt gccggcatgc agcagaacga gcgccgtcag
     7321 tgcgctcgtc aacggaagga cgagccgcgc cagcatcgtc gtgaacagcc tggtcagttg
     7381 atagcatcgc ttcgccgatg cgcgctgctc gagaatcgcg gcgagcttct cgagcgcgag
     7441 ccgattcgac atcgcattcc acgcgttgga ttttcgcttg ataatcgaga gtgccgcgcc
     7501 attggctgcc tcatccgcga tctgtgccgc ttcgaattcg agggatgtcg tatgttgccg
     7561 gtacgcaaaa atgccggtaa cgatgagcat tggacaatag caggcgaccg caacgacgta
     7621 atcgaacttc gagatcagga tcccgattgt cgacagggag atcatctgac cgacaatgct
     7681 gaccactagc atcgagcaac gcgccacctt cggaatatcc gacaggacgg tctgatgtat
     7741 gcgttcatgg gccgcatgaa tgatccacga tgacgcgagg attgcccgca ccttgtctcg
     7801 cgcaacacag tcaatgaacc attgctggat aacgttgacg acaatgcccg atccgatttt
     7861 ccccgcatag gcaagcgcga gcgccaacaa ccagaaatgc gccacttgct gcgtcgcaac
     7921 ggaatcgagt acgtgacgca acgcgtacgg cggcagaagt ggaatcagat atccggtcgc
     7981 gaggatgacg agaacgatca gtggcgccat cagccgcatt tcccgaggta tgctcatcat
     8041 gtacatcgaa gttcctcgcc acctatgctg atcaagcagt ctcgaaactg ttcattgtga
     8101 gtgacgacga gcgcgacgac gccaagtgtg tcgagcccct cgatgaactc ggccacttcg
     8161 cggggggatt tcgcaatgcg atccaacgtc tcgtcgaagc atacgaacaa cggtgtattg
     8221 ccacgcttta tgcactcgcg caccacgttc agcatgcaat cgatgttgtc ctggccggcg
     8281 atgagacggt gccagatacc cagagcctga ctgtcgaagt acagcgtgct gctctcgagc
     8341 tctctcgacg aaagcacccg gttctcgaca aacacctggt tgtcccgtga ttcgcgcatt
     8401 cccgtgatgc tcatcagggc cgtcgttttg cccgctccat tcggcgccat ccagaccttg
     8461 tgcgaatcga gcgtcgtttc gcaggtagcg cccgacagca gacgcagctt cagatgcggc
     8521 cttccgcaaa cagcgtcgct tgcggtggcc gcctccgcgc cggtatcccg cccaaagcac
     8581 tcggtcacgt ggtgcagcga tggcagcgat gcatgcagac gagcgctagt caatgcgaga
     8641 ctcgcgatcg gcgacagggc ttgttcgaga tagatcgtca cggccagaac atagggaaga
     8701 ccgatcgaac tgtggccgat gccgacgacg acggccgcca gataacctac ggttaccatg
     8761 gcgagtgcga tctgcggggt cgacgccgcc gcctgcgcga acagatttgc cgaaagcgtg
     8821 gttctccgaa ctgcgtcgat cgtatgcaag accgtgccaa tactgcgttc ggcgcacccc
     8881 accgtcgtga gcagtcttgc atgagacaga aacagatcga gctggccatt acacctttcg
     8941 cgcgcgctcc gcgccatcgc ggtcaaggcg atgacccgcg acttgggcac cacagcaaac
     9001 acgagcagga cgatcgcaaa caatacgatc cacggaccaa acgcaggctg atgcagccat
     9061 accaccaaca ggatggaccc gacaatcgtg atgtgctggg gcacctgcac gaacaacgcg
     9121 ctgatgacca catcgaatcg ctcgacgtcc gtctcgacga ccgagaacag ctgaccagag
     9181 gacatcgtgg cagccggcac tttgccggca cgaacagcaa ccgcgatgca atcgacccgg
     9241 atgcgctcga ccagtcgcga tagcgtgtaa agcaatgtct tctgcaatgc gaaacctaga
     9301 accgtcgggg cgataacagc cacgccgtac agcgatgccc acttcacctc gccgtgcacg
     9361 ttacctgcga tcgccacgag gtttgccaac gcaagcggcg caagtgagcc gatcacgctt
     9421 aaaacgcaga ctgcgacgcc gattgcgcaa agtcggcgcc ggtcgccgga gcctgcgtgc
     9481 ttcagggcga acgcaagggc atcacagttc ggattcacgg gtcttgaatg cattctagtc
     9541 aggagtacgt atctgaaaga atcagttgag aaccggcttt gctctctttt cgagtgctcg
     9601 gcgcaattcg acggcgaaga aatcccgata ccagctgatc attgcatcga cttgcgtctt
     9661 caattcttgc ctggactctt tctcctgcag gctcggcgac gcccttccgt tcgtcatgcc
     9721 tggcgcagcg ccaatcagtt cgatcgcagc atgcgtgacg gcccgaagga tgcgcgccgc
     9781 ctcgggtacg tagcggttgt cgaatccccc ccgatgtcgg gtccgaatga tgctgtaacg
     9841 cgtgttttcc gcaaacgtat aggcagacgt cacgagttcg aaaaccttca cctcgccgac
     9901 cgacagttcg atctcccggt cctcctcttt cggctcgagg ttttcgtacg tttcgcacgc
     9961 gtcgattgcg gcgccgatga gcgagcgcac ctgattccag tcagtgggca tgttgacgtt
    10021 ccaagttaaa aagtttgacg atgtcgtcga tcaggaaagg caccgataaa gcatcgtttt
    10081 cgagacacgc gtatccgagc gcagcacctg cgcgaccggt ccacaggccc ggcatgtcga
    10141 aatcgccgag gttgaattcc tccttatcca tctgaacgaa ttccgacaaa cggctccatg
    10201 caatcaactc gtccatgcag gccgcgacgg tcgccacgtc ctcttgcatc gcgagcaaac
    10261 ggcgggaaag attcactgcc ccgagcgacc catggcagat cgtgacgttc acgggcgagc
    10321 gccgcctgcc aagcgccgcc tcgatgatcg tgaggtacgg gaccgcttcg gtgaactgtc
    10381 gtgccgcgtg attggaggcc gcgagctcca ttaacgcaag gtagattccg ggcccaccgt
    10441 ggctccatcc gaactcgaaa ggctgcacat tttctgcagc cgatcggacg cgatagtcag
    10501 gccagttggc ttcccttacg caatatttcg acagctccca gcgcgtaagg ctgttcacca
    10561 gttcttctat ccggccttta tgcgcgggtg cgggctcgca tcgacgtgcg tagttcgaca
    10621 atgccaatgc aatgccgatc tgtccatgcg agagtccggt caagcacccg tcttcctcca
    10681 cggaaacgga cttgccgttc ggaatcagga acgcgccgtc ggtttcccgc acttgcgcaa
    10741 gcaggattgt ggatattcct tcggcgagtg accgccattc cgtgtccgcc gtcgtcgagt
    10801 acatgagcgc agcgacgttc aacgcgcccg cgacgccgca gatcagatca ctgccgacga
    10861 agtactgcat cggatgccga gatgccacgg cccgcgcaaa tttgtctttg gcagcggccg
    10921 tcaattccgc cgcgagcggg tgggacacct tcgagctcat tgcatagagc ggcaggattg
    10981 cggacgatag tccgatatag ctgccaccga gctttgtgat ttctcgatcg agctcggata
    11041 tcgccgtacg cgtagccctc gcgaccaggt cgccggcatc gccgcggccg agcaactgca
    11101 tcgccatcaa gatgcccgac gatccgtggt agagatcggt gccgacctgg ccgaattcca
    11161 ttccaccgga cggcgatgtc ttgcagccgt accactcgag ccgctttcga tcaccattcg
    11221 cggcctcctg tcgctcgacg tagcgctgcg ttgcctccaa cgattcccgc gccgctgcac
    11281 cgaagtcgca caaagcctcg gtcgcacggg gttcaccatc gctcgcgctc gttttcggcg
    11341 gaatgagaag actgcttctg taacccgcgc cattcgcaaa gtgaatttcg agcgccttca
    11401 tcgaaccgcg caacagcctg acgccaaacg cgatgcgcgc ctcgctgacc gacgtgacca
    11461 tttgtgccga attctgaatg ccggacaggc tggcgcctgg tatttgcgtc ggatacgcca
    11521 gatacgcagg ctcccgcacc tcgatgccat ccgggtggcc tacgaatcga ggaacatcgc
    11581 caccttcgca agccagcacc tccgcctcga ggagtgacct gttttccgac gaggtggcac
    11641 taaggcagga gcgcagatag tcacgccgct gatgcacgtc cgtcagcagg caggggtgaa
    11701 ccgatgcctg cagtgcaaaa tggtatcccg ccgtcgattg gtggatatag cgcatctccg
    11761 tcgcggcgag ttggcccagc gccacgatcg cccgtggctt tcttggaatc gtcgtcagcg
    11821 caacgcgata accggcttcg agctcgtcga gatagttcca cggcttctgg atctcgccgc
    11881 gaaagcgaag aacgttcaac gatggctcga tcgtcgttcc ggcatcggaa aacgcctcgt
    11941 ccagccgacc ctttccggtg ttctgataga ccgccatgct gcaatactgc gaatttaggc
    12001 cacccagccc ggacgtgtcg attccgacga ggtcgccacc tttccaggtg gccgacggca
    12061 agagacccgt tcccagaagg ttccaagcgc cgtaggtacc gatttcctct acaccgtcgc
    12121 tcccgatctg aggtgtaagc gccgcctcca tgtcgaccgg cacaggcgag tcgccatggg
    12181 caatcaagtt gccattgtgg aggtccgaaa tgccgtatag ctcggaaaag ccgatcagat
    12241 atcccgctcg tgtatagaag cgccgaatgg aggcttcgtc aggcgcctcg cgatagtcca
    12301 cccacttcac ccatccgtgg ctctcaccca gcacatattg cggaagcgtc cagtccgaat
    12361 gaaatccgag atcagacgag aattcctgca atagtgcagt cagttgcgct tccgcatcca
    12421 aatttcgtgg tttgtagcca aaggtattcc gaccgtcgat cgagacaatg acgatgcttc
    12481 ggctgctgca gtgcaactca ccatccgtga gttcgatatt gatcgagcga ccttccaatg
    12541 tggacggcat ctcgaaacgg gtttgaattt cctcgtagtc agcctccaag gccacagcaa
    12601 attcgaacgc gttattgcag aagttcgtcg tgatcgtgga cagcagctgt tccaagcccg
    12661 gatactgcga aagcagattc acgacgcgac ttgggtcgtt cgacaatagg ctgacgaaat
    12721 ccgaatagct gatcgagttc gatcctgtca gcgcctgatg aagctttttt tcgaagagaa
    12781 tcgcttgccg cgcgaataca tccagtcgat tggcgagatt cgtcagaaag gctgcaacga
    12841 tgtccctgtg caccgctcga tgtccaattg tttgctccag tcgacacgtg accgtggtaa
    12901 caaaccataa aagatgacca cggaataggc acgacgtatt cagacgcacc ggactatcgt
    12961 ccgggtacat atagtatttc gctatgcttt cgttcatcag ctaaccgtct ttttttgatc
    13021 gcacaattgg caatcgcgcc aatccccgac ccaagtcggg ggatcgtgtt tcgaatcgcc
    13081 cagctcaacc gtccccatcg tccatcggct gaggaatagg gttaatcggc gtaaacgtgg
    13141 cgttgcaaca gtggttccaa cattgcgtac agcaggtcgt gtaaggattc gacccggagg
    13201 tgtggtattt caagaatgaa gcgatttcat ccggatcctt gatggaaacc cgctccatct
    13261 caagtgcaac cttccgagcc gccgcgtatg cagcaaagct catcgaggtt cctgaaggat
    13321 tgttctgcag acttcgcata ggtgagctcc tagtttggcg attcattgcg gataccaagt
    13381 ctggccctct actgctatgt cacatgcata ttgaggactt ttgaaatgat tcccgaagtg
    13441 agtgatcctt actagctaca aacccttgta gctacaagtt atactgctag ttcttgtagt
    13501 ggcacccgca ttgcgagccg cggtttccgt atatcgccaa cgcttcgacg tagccacatg
    13561 tacaggtacg tgagttttct gccacttttt cctggatgga gttttcaatg tctgaactac
    13621 cgagtactga ttggggacaa attcgagacg ttcttgcggc tgcagtgaat ttttgcgagc
    13681 aattggaggc actcggctat tccgagaact cgcggacgcg atcggctctt gtgaatggga
    13741 caaatgtatc cgctttcgag gtagtaacaa gtgcatggac acttgccgaa gcgacacgct
    13801 acaccgtaat acgatcccga cacgatgcaa acaatgactt gtcctatgta ccagaagccg
    13861 cacggatcct agccgccgcg tcaagtgttt gtgcggaact cgttcatagc ggcggtaagg
    13921 tagatgcgaa tgttgcgata gaacgtctca agacttggct caataccgaa ggggtcgagg
    13981 ccttgaaaac aacgcttggc gagccatgaa tcgccacaat cggcgcagct atgactcaaa
    14041 cgcaccacgc ccagcaaaca gtctagctga cacggcggtc gtacagagta gagaaacccg
    14101 cgcaagctcg ctgtttagtg ggttttttgt ttttcagccg tgcgccgcaa cgcgtgcccg
    14161 ccgtttccga ggtccaagca tcgtgatgaa cgcgcggcag ggaggcgggc catgtcgatg
    14221 cgcacgacgt catgcgcgct ctgccgcggc gcgctcgcgg tggtgctcgc cctcacgctg
    14281 ggcggatgcg acgtgctgac cgcaccgccc gtgcccgact ggccggggcc gcatgcgccc
    14341 tatcccttcc ctgacaacat cccgcatcgc gccgaatgac cggccgcctt gcaccgtaca
    14401 cgctcagccc gtcagctccc gcacgaagtc gagaaacacg cgcacctttg cggaaacgag
    14461 attcgacgca tggtgatacg cgtagagcgg gaatgtctcg tccgcccatt ccggcagcaa
    14521 ctgcaccagc cgcccttccg caaggatgtc cctcgcatag agttcgagca gctgcgcgac
    14581 accctcaccg ccgacacatg cgccgagcag cgcccccgta tcgttgaccg tcagccgccc
    14641 ggtggcatcg aacggcacca cttcgtcgcc gcgatggaat tcccatccgt acggacggcc
    14701 cgtcaccgga tcgcgaatca gcacgcagcg gtgcccgtcc gcgagatccc gcgggtgccg
    14761 cggctcgccg tgacgcgcga cataggccgc cgacgcgcag gtcagcacat gcgtctccag
    14821 cagcaggcgc gcacggtatg acgacggctc cggaatgccg aaacgcaccg ccacgtcgaa
    14881 cccgtcggcg acgaggtcgc ccatccggtc gcgcacgctg atctcgacgg acagctcggg
    14941 gaagcgatcg agaaactcca ccatcctcgg cgccagcacg tagtggccga aggtgccgtc
    15001 cacgttgacc cgcagccgtc ccctgacgcg cgcccgggaa cgcccggcgt cgaccgccgc
    15061 ctcctcgatg ccggccagca gcggcgcgac cgcctcgtag aagcgccgcc cttcgtcggt
    15121 caacgtgatc gcacgtgccg ttcggttgaa gatccggatg ccgacgcgct cttccagccg
    15181 cgcgaccgcg cggctcaccg ccggctgcgt caaccccatc gcctcgcccg cgcgcgcgaa
    15241 ggtaccggcc tcgatcaccg ccgagagcac accgataccg ctgaggagcc tgctgtcgaa
    15301 tgccatgaga catactttta gtcattcttg atctgatcat tattcattat ttttattgac
    15361 cgaggaagcc tacattagtc ctgtcgccgg atcgcccggc cctcacgaac caaggagcag
    15421 gacatgaaca catcgaaaca ggtcgccctc gtcacgggct cgtcgcgcgg catcggtgcg
    15481 gaaatcgctc gccgcctcgc ccgggacggc ttccgggtcg tcgtgaacta cgccggtggc
    15541 gccggcccgg cgcgcgaagt ggtcgaggcg atcgccgcga acggcggcga ggccatcgcg
    15601 gtacaggcgg acatcgccga cccggtggcg gtggccgcgc tgttcgatgc ggccgagcag
    15661 gcattcggac acatcgacgt ggtcgtcaac agcgcgggtg tcatgaagct cggcgcgatc
    15721 gccgactacg acgacacgac gttcgaccag accgtcgcga tcaacctcaa aggcaccttc
    15781 aacgtcagcc gcgaggcggc aaagcgcgtg cgcagcggcg gccgcatcgt caacctgtcg
    15841 tcgacgatgg tcggcgtgcg tctccccacc tacggcgtgt acgtcgcgac caaggcagcc
    15901 gtcgagggac tgacgcaggt cctcgcgcag gaaatgcgcg gccgcggcat cagcgtgaac
    15961 gccgtcgcgc cggggccggt cgcgaccgag ctgttcctgc agggcaagag ccccgagcag
    16021 gtcgatcgcc tggcgaagat gaacccgctc gagcggctgg gccaacccgc ggacatcgcc
    16081 ggcgtcgtcg cgttcctcgc cggccccgac ggcgcgtggg tcaatggcca gatcctgcgc
    16141 gccaacggcg gcatgtgctg accgacgcag gaaccgcgca caccgcaagg gccgcccggc
    16201 gtggcccctc cccacccgct tgcaggagat cgatcatgaa ggaagtcatt ctcgtcaccg
    16261 gcgcgtccag cggcttcggc ctgctgacgg cccaggcact cgcccgcgcc ggtcatacgg
    16321 tctacgcgtc gatgcgcgag agcgccggcc gcaatgcgcc gcgcgtcgcc gccatcgccg
    16381 actacgcacg cgagcacggc gtcgacctgc gcaccgtcga actcgacgtc ggcgacgacg
    16441 catccgtcgc cgccgcgatc gagcgcgtga tcgcggacaa cggccgcctc gacgtcgtcg
    16501 tccacaatgc cggccacatg gtgttcggcc cggcggaagc gttcacgccc gatcagctgg
    16561 cgcagctcta cgacatcaac gtcgtgtcca cgcagcgcgt gaaccgggcc gtgctgccgc
    16621 acctgcgcag ccggggccgc ggcctgctgg tgtgggtgtc gtcctcgtcg gcgcgcggcg
    16681 gcacgccgcc gttcctcgca ccctacttcg ccgcgaaggc cgcgatggat tcgctcgcgg
    16741 tgtcctatgc ggccgagctc gcgcgctggg gcatcgaaac atcgatcgtc gtaccgggcg
    16801 cgttcaccca cggcacgaat cacttcgccc acgcgggcaa gccggccgac acggcggtgc
    16861 aggccgcgta cgacgacggc ccctacgcga gggtcgccga gcaggcattg caaggcctcg
    16921 ccgcactcga gcccgcggac gccgatgccg ccaccgtcgc gacggcgatc gtcgacatcg
    16981 tcgccgcgcc gtcaggcaag cgcccgtacc gcgtattcgt cgatccgtcg caggacggcg
    17041 cggaggaagt gttccgtgtt ggcgatcgca ttcgccgcga gatgttccgc aacatcggac
    17101 tcgccgacct gctcacaccg cgcgtcggca actgatcgcg ccgagcaccg ggccggccgg
    17161 cgcgcatcag tctcgctcgc agaacccgag gattgcctcc gcgaccgccg ccggcgcctc
    17221 ccgctgcgga aagtgcccca cgccgtccag cacctgtcgc gcgtagcgcc ccgtgaagaa
    17281 ccgctcgcgc ccggccgagc cgtccgggtg attgcaggca tccgcgccgc catgcagcac
    17341 cagcgtcggc accgatagcc ggggcgccgg gttcagtcgc gcgtcgtcgt ccgcataggc
    17401 cggcgtgccg ggcgcgaagc cccaccgctg ccggtacgaa tgcagcacga cgtcgatcca
    17461 gtcgggcccg tcgaacgcgg tggcagccgc ttcgaattcc gcctcgcggt accagcccgg
    17521 cggcgaccac gtatcccaca tcaggcgcgc gaatgcgcgc cggtcgtcgc gcaacgcctg
    17581 ctcgccgcgc ggcgtcgcca tgaaccagtg ataccaatag ttgcgcgcct gctgcagcga
    17641 cagcggctgc gcgggatcgt tggtgccgta gccgaccgac agcatcacca ggtgcgacgc
    17701 gacgccgtcg cgcagcccgc atgcgttcgc gaccgcgcgg gcgccccagt cgtgtccgac
    17761 cagcacgggc cgctcgaggc cgagcacgtc gacgaattcc agcaggtcgc gcccgagcgc
    17821 cgcgagctgg ccgctgcgcg gcaccgtcgt atcgcgaaaa cgggtcggcg cgaaaccgcg
    17881 cagcgcgggc gcgagcacgc ggtagccgcg gacagccagc gcctgcgcga ccgtctccca
    17941 gccgaccggg ctgtccggcc agccgtgcag caacacggcc acgcgttcgg cgcgcggatt
    18001 ccattcgaga taagcgagtt cgagcgacgc ggtcgccgca aatcgataag cggtcatcgt
    18061 gcactccggt gggtcggttt gaaggtcgat ggtagagcgg cctctcatca cgattcgcgg
    18121 cgtatcatga tccattcttc gaatatcgcg ttgaatcgac ccatggaacc gccaatcgat
    18181 cgcgcatcga ccgcgctcga catcacgctg ttgcgcacct tcctcgaagt cgtcgacagc
    18241 cgcggcttcg cgcccgccgc ggagcgcctc gcgctgacgc cgtccgcggt cagcggccac
    18301 atcaagcggc tcgagcaggc agccggcacg gtgctgctcg cgcgcaccac gcgccgcgtc
    18361 gcgctcacgc cggccggcga cacgctgtac gcgtacgcgc gcaacatcgt cgacatggag
    18421 cgcgaggtgc gtgcgcggct gcgcggcgcg cccgcgcatg gccggctgcg cgtcggcgcg
    18481 tcggaggact tcgcgggcac gtggctgccg caggtgttgc gcacgttccg cgacaaccat
    18541 ccgcgcacgt cgatcgagct gaaggtcggg atcaccgcgt cgctgctgcg cgagcaagcg
    18601 ctgggccggc tcgacgtcgt gttcggcaag caatgccggc aggtcgacgc accgggcgaa
    18661 ctgctgtggg aagagccgct cgtgtgggcg ttcgcgtcgg atacggcgct taacgccgaa
    18721 ggcgacgtgc cgctcgcgct gtttccggag ccgtgcgtgt atcgggaagc cgcggtggcc
    18781 gcgctcgccg ccgcgctgcg gccgtttcgc gtgctgttcg aaagcggcag catggccggg
    18841 tgcgtatcgg ccgcgctcgc cggcttcgcg gtcacggcgc tcgcgcgcag ccagttgcgc
    18901 gacgggctgc gcgcatgcgg gcccgacgac ggcctgccgg cgctgccggc cgcgcgcttt
    18961 catgcgttcg cgtcgaagcc cgacggtgcg gcagccgcgc tgatcgacgc ggtgcgggcc
    19021 accgggcgca gccggcagtt cgccgcgcgg ttcgactgaa cacgcgcgct gcggccgcgg
    19081 cccacgtcga caagctcgcc cctgcctcgg tcggcgcacg cgagcgcggc gcccttttca
    19141 gtcgccgcgc gcggccacac ccgtgtcgct cagcgcatcc gccatcaact cgccgaacca
    19201 ctcgatgaac gcattgagcc gccgcgaccg gtgccggcga tgcggataca cggccgacac
    19261 gtccatcggc gcggcgcgat ggcccggcat cacctcgacc agcgcgccgc tgtcgagcag
    19321 gtgcgcgacg tcgaagcgcg gaatctggat cagccccatc ccggcgatgc agctcgcgat
    19381 ataggtttcg gcgttgttga cgatcacgcg gctcggcagc gccagcgtgt gctgcccgcc
    19441 atccgcgcag tattcccagc cgagttcgcg cccggtcgtc ggcgacgcat agccgatcgc
    19501 ccagtgtccg tgcgcgagcg catcgggatg ctcgggcacg ccgcattcgc gcaggtagtc
    19561 ggggctcgcg cagttgatca gcgtgaactg tccgagcggc cgcacgacga ggctgctgtc
    19621 cgcgagccgc ccgacccgga tcgcgcagtc gacgccctcc tgcacgagat cgatcgtgcg
    19681 gtccgtcgag ccgagcgaca gctgtagctt cgggtggcgg cgaaacaacg acggcagtgc
    19741 cggcgcgatc acgcggcgcg cgatccggct cggcgcatcg acgttcagcc gcccgaccac
    19801 gtcgcgatcg cgacgccgga acagccggtc gagttcgtcg gcttccgcga gcaggcgccg
    19861 gccgcgctcg agcagcagcg cgccgtcggc agtcagctgg acttgccgcg tcgtgcggtg
    19921 caacaggcgc gtgccgagcg ccgcctcgag ttgctggaca gcggccgaca cggtcgcgcg
    19981 cggcacgtcg agcgcgtgcg cggccttgat gaagctgccc atctcggcaa cctgaaggaa
    20041 gattctgacc tggtccagct tgtccatcgg agcaaaacgt aggttcggac gaccgtcgcc
    20101 ggcacccgcc gcatggcgcg gccgagcccg gcggcacagg aaaagcgggc gcgcggcttg
    20161 gtggccgcgc gcccgtccat tgtccatgca aacggtccat tgcgggtcgc cgcgcgcacg
    20221 cggcgcccgc cggcacggcc cgttacttgg tcgtatagcc gccgttgatc aggatcgtct
    20281 ggccggtgat ccaccagccg tcggtcacga gatgacggat gaacggcacg acgtcctcga
    20341 tgtcggtgag gcccgtcttg ctgaacggcg acagcgcggc cgccgtcttg tgatacgcga
    20401 ccgcgtcggc gccttcggcc ggatagaaga acggcgtgtc catcggcccc ggcccgaccg
    20461 ccgtcaccga gatgccgcgc gcgccgtact ccttcgacgc ggcgcgcgtg aaatgctcga
    20521 ccggcgcctt cgacccttcg taggccgcat agaacggcgt gaacgcgccg agcagcgacg
    20581 tcacgagcgt gacgagcttg ccatgatcct cgaggtgccg ccccgcctcc ttgatgaaga
    20641 agaatgccga cttgctgttc accgcgaaca tctcgtcgta ttcggcctcg gagatgtcgg
    20701 tgaacggctt cttcagcacc ttgccgacgg tattgatcgc gatgtcgatc ttgccgaagc
    20761 gctgcttcgc gtcgtcgaac agtttctcca ctgcagcggc ggtcgtcagg tcggcctgga
    20821 acgtcgcggc ttgcgcgccg gccgcgcgca cggcggcagc cgtctcttcg gcctgcgcct
    20881 gcgacgccgc gctgttgtag tgaattgcca ccgccttcgc gccgtggccg gccaggtccc
    20941 gggcgatcag gccaccgaga ttcttggcgc cgcctgcgat caggacgacc ttgtctgcga
    21001 gcgtgtgagt ggccacggtt gactcctttc agcgttgaat gaagctacga gtgtaggcac
    21061 gcacgacgcg acggtcagcc gggcacggct ggatgaatta tccagaaaaa cgatccaatc
    21121 attcggccgg aatggtgggc tgccgcactg acggcggcta ctcgatctgc ccgacgcggc
    21181 acgatggtgg cggccttccg gccgcacggc agcgaatcga atgccatgga ctttccgtga
    21241 agaatggacg cgcgcagcgc tccgggagct caccagcgcg agcgcgttcg tgccggcgcc
    21301 ggcacgccgc ttgatagaat gcgcgcgcta tggatctcga aagcattctc tacacgcagg
    21361 gcttcggctc gcgccgccag tgccgcggcc tgatcgaaac gggccgcgtc accgtcgcgg
    21421 gcgcgagcgc gaccgacccc gacgcgtcgt tcgacaccga cggcctcgtc ttcacggtcg
    21481 acggcaccgc ctggccgttc cacgcccgcg cttatctcgc actcaacaag ccggccggct
    21541 acgagtgttc gcgggacccg cagcaccacg cgagcgtgtt cagcctgctg cccgcgccgc
    21601 tcgtcgcacg cggcgtgcag tgcgtcggcc gcctggacca ggacacgacg ggcctgctgc
    21661 tgctgtccga cgacggccag ttcgtgcacg cgtacacgtc gcccaagcgc aaggtgccga
    21721 agacctacgt cgcgaccgtg cgccacccgc tcgacgacac ccagctgaac gcgctgcgcg
    21781 ccggcgtgca gctccacggc gagccgaagc cgatcgcggc ggtcgccgcc cacgcgcgcg
    21841 acacgcacgc gctcgcgctg actgtcctcg aaggcaaata tcatcaggtg aaacgcatgg
    21901 tcgccgcggc gagcaaccgc gtcgaggcgc tgcaccgcga aagcatcggc ggcttcacgc
    21961 tgccggagga tctcgcgccc ggcgcgtggc gctggctcgg ggaaggcgac ctgtcagcgc
    22021 tgcgcgatcc cgtcaaaacc ctctaaggga aaatccgcac gaccgttcgg tgtccggccg
    22081 catcgcggcc gcacgatccc ccgctatact gaaatcacaa gctgtacgag cagcgatgca
    22141 gggggagaca tcatgaacat caatcattcg ttggaactgt cgtacgtgat gatcgcgttc
    22201 gcggtcatgg gcgtcatcgt gatcggcgca ctgctggcca tgatgcacag gaagcacaaa
    22261 tacagtccga acctgatcgg cgcgctgatc ggcgcgttgc tgtgcttcct gctgatcgag
    22321 gcgctaccgg cgctgacctg acgcgccgcg cggcgtgagc gtttgaagga attcgtctac
    22381 ggtcgggtag cgcaacgtca cgcacaattc ggtcttgagg cgtgcattgg acaggcgccg
    22441 cgattcgcgc atgaacgaca gcagcgtcgg ctcgagctga tgctcggcgt ccgcgcggct
    22501 gatgcgcggc ggcggcggca ggccgaacgc ccgcgcgacc cggtcgaaat actctcccat
    22561 ccgcagttcg ctgtcgtccg acgcgtgcac ggcgcgcgcc ggcttgccgc gcacggccgc
    22621 gcggcgcagg atcgtcgcga gatcgtccgc gtggatgtga ttcgtgtaga cgtcgtcggc
    22681 cgcatccagc gccggcgtgc cgcgctcgag ccgcgcgagc ggcagccggt tcgccgcgta
    22741 gatgccggga atgcgcacga tgcgcgcgga cagcgcgccg cgtaccgtcg ccgcccgcaa
    22801 ctgacgctcg gccgacacgc gccggaacgc gcgcggattc gcggggcgca gcg
//
