LOCUS       NZ_CP066713            21341 bp    DNA     circular CON 14-APR-2024
DEFINITION  Staphylococcus pseudintermedius strain DSP026 chromosome, complete
            genome.
ACCESSION   NZ_CP066713
VERSION     NZ_CP066713.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2567628)
  AUTHORS   Ferrer,L., Perez,D., Fonticoba,R., Vines,J., Fabregas,N.,
            Madronero,S., Meroni,G., Martino,P., Martinez,S., Cusco,A.,
            Migura,L. and Francino,O.
  TITLE     Whole genome sequencing and de novo assembly of Staphylococcus
            pseudintermedius: a novel pangenome approach to unravel pathogenesis
            of canine pyoderma
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2567628)
  AUTHORS   Ferrer,L., Perez,D., Fonticoba,R., Vines,J., Fabregas,N.,
            Madronero,S., Cusco,A., Migura,L. and Francino,O.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2020) Servei Veterinari de Genetica Molecular,
            Universitat Autonoma de Barcelona, Edifici V, Travessera dels
            Turons, Bellaterra, Barcelona 08193, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUL-2020
            Assembly Method                   :: Flye v. 2.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 303x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016455085.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 20:32:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,471
            CDSs (total)                      :: 2,390
            Genes (coding)                    :: 2,301
            CDSs (with protein)               :: 2,301
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 63 of 89
            Pseudo Genes (incomplete)         :: 28 of 89
            Pseudo Genes (internal stop)      :: 9 of 89
            Pseudo Genes (multiple problems)  :: 10 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2407801
            Orig. end                         :: 2429142
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066713.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21341
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="8"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21341
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21341
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11341](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11341
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(158..173)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
     misc_feature    737..756
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.74"
                     /tool="antismash"
     misc_feature    740..754
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 22.46"
                     /tool="antismash"
     misc_feature    800..815
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.22"
                     /tool="antismash"
     misc_feature    complement(1050..1064)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     misc_feature    complement(1678..1692)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.25"
                     /tool="antismash"
     misc_feature    1958..1971
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.06"
                     /tool="antismash"
     misc_feature    complement(2096..2109)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: weak, score: 15.72"
                     /tool="antismash"
     gene            2508..3386
                     /locus_tag="JGZ50_RS11585"
                     /old_locus_tag="JGZ50_11585"
     CDS             2508..3386
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614835.1"
                     /locus_tag="JGZ50_RS11585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11585"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_020220086.1"
                     /transl_table=11
                     /translation="MELKQLKYFVEVAKREHISEAALELNVAQSAISRHIHNLENELET
                     SLFYRRGRNVFLTAEGKQLLEYAKQILEQVDLTLSQFQTQVQQQQSVFTIGYVDGSIGQ
                     ILPQVLQTIENELSLSLIPTLLDEQETLQALRAQEIDFALTTVTTTDPTFEIVPLVEET
                     YVLYGDLHAPMMNVPNPPLSHILKQPLYLLEPIPTDFKTYLITHADKPVRVLNQEQFAR
                     FILRNQKGFVLAPTYVNLYSQNQQWKKISLSHTDFKKTLRLIYRRDLQKPLRDEVIQII
                     MTHIQQRSVYH"
     gene            3399..4508
                     /locus_tag="JGZ50_RS11590"
                     /old_locus_tag="JGZ50_11590"
     CDS             3399..4508
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614836.1"
                     /locus_tag="JGZ50_RS11590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11590"
                     /product="YibE/F family protein"
                     /protein_id="WP_198461190.1"
                     /transl_table=11
                     /translation="MKQLSKKINTIVIVVSIIVAICAIVFTRLNSSFYHIPLGEVTKIE
                     SHHQEKSVDEQHNQDVKYKDVLQVKLLNTKQQGDTLHVEHRYNASKTEEQAYQPGDKVL
                     LHKGKNQKDTYIIEKKRDTVLVTVISAFFIALLIVGQRIGLQSILSLVINAFAILLAIS
                     LYHAYPQLNLFLLMSLAVMIATILTLWLVIGWSMRTIVTIVSTLLGTFICIFIAWSVIG
                     LTHGQGIKYETMSFLTIQPRTVFLTSVMVGTLGAVMDVAITISSGMYEVLKRSPHISMQ
                     RWVLAGRNIGRDIMGTMTNILLFSYLAGSLPMLLLYLKNGNTLTYSISMNWSLEISRAI
                     TGGIGIVLTIPLTIFLMRLWLSLRGGATR"
     gene            4505..5278
                     /locus_tag="JGZ50_RS11595"
                     /old_locus_tag="JGZ50_11595"
     CDS             4505..5278
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220087.1"
                     /locus_tag="JGZ50_RS11595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11595"
                     /product="YibE/F family protein"
                     /protein_id="WP_063284950.1"
                     /transl_table=11
                     /translation="MNAIVILGLILFILMLIFGGKTGLVSFLTLFLNFIILFITVLAIV
                     FGAPIYVVTFIFCIIVSMVNLFLLNRFNTKTLAAFIASTVTTLLMIVAVYLSVHWGHLQ
                     GFTQEEQDETYIFSLNIGIDMEQFMIFTVLLAVIAAVIDLAITISSPVFELHETNPSLS
                     ERELFHSGMRVGREILATSANTIYLALIGGSMTIVFWFFNLHYSFGHMLNAKLFAQEVI
                     TIALGGIAIAVCIPITAMITAWLVKHRHQLPFHLD"
     gene            5327..7588
                     /locus_tag="JGZ50_RS11600"
                     /old_locus_tag="JGZ50_11600"
     CDS             5327..7588
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166373.1"
                     /locus_tag="JGZ50_RS11600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11600"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_187532188.1"
                     /transl_table=11
                     /translation="MTAIHIHGARQNNLKNIDVSIPKHQLTVVTGRSGSGKSSLVFNTI
                     AAESERLLNETYSSYIQHQLTQYEKPDVDHIENLPVAMVINQKRLGGNSRSTVGTISDI
                     YASVRLLWSRIGTPFVGYSDVFSFNNPNGMCEHCQGLGYVEDIDLNELLDFDKSLNEGA
                     IRFPSFKPDSWRGKRYRYSGLFDNDKKLKDYTKEELDTFLYTEPTRLKNPPAEWPKTAK
                     FEGLIHRFRRSFLINDNFEKKRFLKDVERVVTKQTCPVCHGQRLNQKVLSCKIHGLNIA
                     DFTVLTIEETLPFLEQIDSDKATYIIEPLKAQLQALNDIGLNYLTLARETTTLSGGESQ
                     RIKLIRHLNSPLTDLVYIIDEPSVGLHPADIEKINEIMLNIRDKGNTVIIVEHDPDVIK
                     IADHVIDIGPGAGKHGGQITFEGSYAQLKQSDTDTARALTRQHHLKQSAIRDNQAWLHL
                     EHLQHNNLQDVSVAIPKNAQTVVTGVAGSGKSSLIKGGFAKHEDAILIDQKGVHTSNRS
                     NLLTYTGIFDDIREFFSKATGLKKSMFSYNSDGACPNCNGKGVLKTELAFMPDFSQVCE
                     VCGGTRYRPEVLETKVDGYSIADVLALTVEEGLSLFQTHDAIAQTLSALQSTGLGYMTL
                     GQSLDTLSGGEVQRLKLTRYMIEPVTEKIFIFDEPTTGLHEDDIPILQARFDQLIEEGH
                     TVILIEHNITMMTRADWLIDVGPGAGNQGGRILYSGPPAGLKNVAESRTAPHLFGSLSE
                     "
     gene            complement(7655..7975)
                     /locus_tag="JGZ50_RS11605"
                     /old_locus_tag="JGZ50_11605"
     CDS             complement(7655..7975)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /locus_tag="JGZ50_RS11605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11605"
                     /product="transposase"
                     /protein_id="WP_037544019.1"
                     /transl_table=11
                     /translation="MKQSTKSNTNKSLFKNLTWDYFKAFINKKLSDPKTKHIYQKRKID
                     VESTFVNLKANLGFQRLSVRTQSKVECELGIALMAVNIRKLAKISARFRSLIRKKPSNS
                     KN"
     gene            complement(7979..8578)
                     /locus_tag="JGZ50_RS11610"
                     /old_locus_tag="JGZ50_11610"
     CDS             complement(7979..8578)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /locus_tag="JGZ50_RS11610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11610"
                     /product="transposase"
                     /protein_id="WP_037544021.1"
                     /transl_table=11
                     /translation="MRQSKKAIQDFKDRKLKYDKQMEIYGDRKSYSKTDHDATFMRMKD
                     DHMRNGELKPGYNLQIATNNQFVLAFGVYSYPGDTRTLKPFLKSIHKLYGDIPEYIVAD
                     AGYGSEYNYTVILDEFEKTPLITYSMYLKEKQRKYKNNPFITANWEYNVIEDYYICPNK
                     KTLHFQSYRKRRDGYGIQRDFKLYACEACVGCPLRS"
     gene            complement(9036..9674)
                     /locus_tag="JGZ50_RS11615"
                     /old_locus_tag="JGZ50_11615"
     CDS             complement(9036..9674)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024934.4"
                     /locus_tag="JGZ50_RS11615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11615"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_199274765.1"
                     /transl_table=11
                     /translation="MVELLGIKEIIKEKGINNKLCKGEYFQENFEKNIYLVDKGILYVH
                     QDNIDGTTLIYKIIGPDSLFICDNSKYFCGKTEVVFYKMLISSIINDEKICREYIKLLI
                     NENVKKDMFIRDMLTKDKVCRLLSILVRLANTFGEEEGRMIVIKIKITQEELAQYCGTT
                     RENIARIMKQLKDRKIVDTSSRFIKILSLEEIKQMIPCEGCNSFVCKTF"
     gene            9814..10029
                     /locus_tag="JGZ50_RS12640"
     CDS             9814..10029
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022861.4"
                     /locus_tag="JGZ50_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="subtilosin A family bacteriocin"
                     /protein_id="WP_277922907.1"
                     /transl_table=11
                     /translation="MVSNKGCSTCSIGAACLIDGPLPDFRSHGNYWNFWTNFLALFVCR
                     QNDRIYHSLSAYFLLRGDRNESIYIF"
     gene            10001..11341
                     /locus_tag="JGZ50_RS11625"
                     /old_locus_tag="JGZ50_11625"
     CDS             10001..11341
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115546.1"
                     /locus_tag="JGZ50_RS11625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11625"
                     /product="radical SAM protein"
                     /protein_id="WP_306419673.1"
                     /sec_met_domain="subtilosin (E-value: 1.1e-173, bitscore:
                     574.9, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 9.9e-21,
                     bitscore: 71.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 5.9e-41, bitscore:
                     137.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.4e-21, bitscore: 74.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.5e-11, bitscore:
                     39.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1e-08, bitscore: 32.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMNQYIFFNDNARLHQLPHGGVIEVKNGMFKDEVFDFEYLDLNS
                     SAFEACTYFDGSMTIIDILKDMCQKYKCDINDHIEWYTNLVNDLYKKNLINLVSNPVKK
                     NLNISGSTEYITPLHAVFEITHKCNLKCAHCYLESSPQVQDTLSLDEFIMIANNMYENG
                     ILTCEITGGEVFVHPNAKEILEFALKKFKKVGILTNGTLLKPDILDLLIKYKKKIVIGI
                     SLDSVDPEKHDNFRGKKNSFNQTCKTIKKLSENGLFVRVGMSIYEDNMWEINDMANLVR
                     KLGASAFSYNWIDDFGRGKKMNQLKLNKLNNLSFAEFEVDVVKNNRDIIPLVPLTKNKA
                     NNCGAGWRSIVMDPNGNIRPCALFPKEFVIGNLKEQSYKDVFSSEIVNRLYSLQSPQKS
                     KFCSDECSFKDYCAGCYLKGLNSNKNHRTNYCGWVKNQKLENLVEQI"
     aSDomain        10079..10288
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JGZ50_RS11625_Subtilosin_rSAM_RRE.1"
                     /evalue="1.20E-22"
                     /identifier="RREFam018.1"
                     /label="JGZ50_RS11625"
                     /locus_tag="JGZ50_RS11625"
                     /protein_end="96"
                     /protein_start="26"
                     /score="71.1"
                     /tool="antismash"
                     /translation="KNGMFKDEVFDFEYLDLNSSAFEACTYFDGSMTIIDILKDMCQKY
                     KCDINDHIEWYTNLVNDLYKKNLIN"
     gene            11506..12204
                     /locus_tag="JGZ50_RS11635"
                     /old_locus_tag="JGZ50_11635"
     CDS             11506..12204
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="JGZ50_RS11635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11635"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_126511031.1"
                     /transl_table=11
                     /translation="MMSIHLNNLCIWYEPENLIIKNANLYLQKGKIYGLLGKNGSGKTT
                     LINTICGVIPSFSGDIIINNLNISKFNYQARLERFYVPDSPPVISQMTSKQYISFVLNM
                     YQQTLSQEHLLRISKKYNFERYLDIRMNELSFGNKKKAALICSILLDVPIKIFDEPLNG
                     LDIESIDLFVQDLFKMTKEDKCVILSSHLLDIVKKLTSNIIYINNKHCFQFTLNDESDI
                     RKVLSDYDKE"
     misc_feature    complement(12674..12686)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            12674..13465
                     /locus_tag="JGZ50_RS11640"
                     /old_locus_tag="JGZ50_11640"
     CDS             12674..13465
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGZ50_RS11640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGZ50_11640"
                     /product="hypothetical protein"
                     /protein_id="WP_126511032.1"
                     /transl_table=11
                     /translation="MTISLLLALFLSPFFNKFISLVLLILVLLGVSIFTNFIKFNVKKR
                     KKPTKATVNEISILKWEFKKFFIEKTNVIGIISMFLFLNILNYNIESIDGMTVEFGLKY
                     FLILLIISSISPLNLMFSSDKELRKIATYMPVKKRSIFMAKILVSTLISQFFLSIVVFI
                     NEMLFQEKLGLLYFKVSILLFFLTFLRLKLDMIKPILDYEDKMELWRNPKKYLSLMIVI
                     PPLFVAVALNFYISLVIILSGCLVLELYSQLYGKEDFFGYK"
     gene            13452..14549
                     /locus_tag="JGZ50_RS11645"
                     /old_locus_tag="JGZ50_11645"
     CDS             13452..14549
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGZ50_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGZ50_11645"
                     /product="insulinase family protein"
                     /protein_id="WP_130882718.1"
                     /transl_table=11
                     /translation="MDINNAINIYKYHVYINKISGVENFTINQLISEILNEKFKALNDY
                     SIIPYTTTSVLGKDFYNIFYLKTLRNRYVDLDYNYWLNSFYNNFQMSDNECYLALEKLI
                     NKIKKYQLNPMNINKLLVKDKLYPNSLLGSKRLGTIETLNMNQISQELVLQRIPESIYA
                     YNLCISKIKGELNIHKLQNIKYASPFFIPHIVSQKVPPLINGQSINTICYYFESNDEYS
                     KTIYGPMLQGYLTQYGHSILFKKLRIEEFQLYHFEAHFDQETNILFIQYIVDENWKIKV
                     WNLIISEVMDLNINKEEFQTMKIFLSNEYRFKFDKSFGELNHILSLGNKFLQSNNIFKA
                     IQDIKIQDFIKFLDNKKMINIVYEG"
     gene            14552..15508
                     /locus_tag="JGZ50_RS11650"
                     /old_locus_tag="JGZ50_11650"
     CDS             14552..15508
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012879.4"
                     /locus_tag="JGZ50_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11650"
                     /product="insulinase family protein"
                     /protein_id="WP_199274767.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 7e-08, bitscore:
                     29.7, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVTKLFYADLDQNLYNLFQNEIKVTYFNKSDSYINQIKAVVNIG
                     GYQYQTGAAHFIEHLKFWKENNNLYDLMNYFGTIMNANTTEYETNFLLYCSKENTVSTL
                     TNFTSYLLNHSYTIEEFNKEKKIILNEVKGYHSILVDENEKLEYVKKIIGDENQINDIS
                     KRYLENLSSICYQKRNIHYYLIGDFSEYIHKSREISKEKIELVVNSDLIIHDYDNTELF
                     LKTLYFHINKFINYYFQNKSLVVNFNKLYNTKKIHDMQLDDFISYIISYIVNVYEDSDL
                     LIEFLENWKFTRGDFTKIGNLLEDQEKLSILLNEAFM"
     gene            15505..16113
                     /locus_tag="JGZ50_RS11655"
                     /old_locus_tag="JGZ50_11655"
     CDS             15505..16113
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JGZ50_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JGZ50_11655"
                     /product="hypothetical protein"
                     /protein_id="WP_037544039.1"
                     /transl_table=11
                     /translation="MKKTPIVLLFTFAIVLELSPLKSHLVKLLIKSQLLNPYSWSSFLF
                     ITLLFSIILTPIQGVFYSFNNKMQIVNSVYIKNKFKMTEEVIEISKKIKLPTKKQVFLI
                     LLINVITYDVFISILSGFKLNTPLVAFIPIGIIFMISTYFLVYRFCKQRINHKILIFLM
                     SITFSCVILSYVKEEIVIFIVIEIIVFYLYNMFLKIIKR"
     gene            complement(16564..17079)
                     /locus_tag="JGZ50_RS11660"
                     /old_locus_tag="JGZ50_11660"
     CDS             complement(16564..17079)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166374.1"
                     /locus_tag="JGZ50_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11660"
                     /product="hypothetical protein"
                     /protein_id="WP_187530648.1"
                     /transl_table=11
                     /translation="MNQVTKIAVATTLSLGTLLGATAGASAIHADAHAATEQQTPYYTY
                     NGLFNFKGNKALEDNNFYRALQHDNFKYEGLKVGQSTFADVKKAVGNDVKKYYEEKGVT
                     YYEKNDVIFGINSEGKLVNMTLLIEKINHSDKSVRDHVKQGEIYDAKTTHVAFYSGNSI
                     VIKAKESR"
     misc_feature    complement(17214..17225)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.71"
                     /tool="antismash"
     misc_feature    17251..17267
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.15"
                     /tool="antismash"
     gene            17384..17659
                     /locus_tag="JGZ50_RS11665"
                     /old_locus_tag="JGZ50_11665"
     CDS             17384..17659
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728571.1"
                     /locus_tag="JGZ50_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11665"
                     /product="hypothetical protein"
                     /protein_id="WP_015728571.1"
                     /transl_table=11
                     /translation="MAKKSKKSLSVLSTALTGATLVVDFYNSYIYRSKNRKLSYISVGL
                     GLVDVVLSFYLSLGAKSKFTKAWSFFSASRQVWSGIQKIQAIRTRG"
     gene            complement(18039..19046)
                     /locus_tag="JGZ50_RS11670"
                     /old_locus_tag="JGZ50_11670"
     CDS             complement(18039..19046)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498204.1"
                     /locus_tag="JGZ50_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11670"
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="WP_014614841.1"
                     /transl_table=11
                     /translation="MRKKFIAAVIGTTAAATALSAHADASTTYRVQPGDSLWAIATKYN
                     ITIAQLKQYNGLNSNLIFPNQVLKVSGGSSTSRTTTHHSSHSTTSSTVYTVRYGDTLSG
                     IAARYGTTYQNIMKWNGLNNFLILPGQKLNVSGPSTTPSRSTAKKPAPKTSSRNASYYT
                     VQPGDSLSLIASKYGTTYQHIMELNGLTSFLIFPGQQLKVSGSAPSRQTTPTPSPSYQS
                     PTFNHQNLYDWGQCTWYVFNKRKEMGRPISTYWWNANAWDDNAARDGYTINNQPAVGSI
                     LQSDLGYYGHVSYVERINADGSILVSEMNFTAAPGILTYRTVPAHRVSAFKYIH"
     gene            complement(19384..19665)
                     /locus_tag="JGZ50_RS11675"
                     /old_locus_tag="JGZ50_11675"
     CDS             complement(19384..19665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166378.1"
                     /locus_tag="JGZ50_RS11675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11675"
                     /product="hypothetical protein"
                     /protein_id="WP_201800462.1"
                     /transl_table=11
                     /translation="MNRIRVVYIVNVLNYLFLIVGGLICVQLMLAFGDLLLYFEATSLA
                     AGIFSLWHLNADDAKLQKVGLIWFIINLLNIFVLTPLIILVLFFGISF"
     gene            complement(20186..21328)
                     /locus_tag="JGZ50_RS11680"
                     /old_locus_tag="JGZ50_11680"
     CDS             complement(20186..21328)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036666.1"
                     /locus_tag="JGZ50_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_11680"
                     /product="bifunctional cystathionine
                     gamma-lyase/homocysteine desulfhydrase"
                     /protein_id="WP_014614844.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.4e-05,
                     bitscore: 20.0, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 4.1e-07, bitscore:
                     26.4, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.2e-10, bitscore:
                     36.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKTLLIHCGNTTDDYTGAVTTPIYQTSTYEQDAIGELRQGFEY
                     SRTANPTRSSLESVIADLEHGNYGFAFGSGMAAISAVIMLLDQGDHIIVGSDVYGGSYR
                     AMTRVFTRFGIEFDFVNTTDVQNIEDKIKDNTKMLFIETPSNPLLRITDIQAVSEIGKQ
                     HELMTVVDNTFMTPYYQTPLSLGADIVVHSATKYLGGHSDVVAGLVAVKDETLAERIAF
                     VQNSTGGVLGPQDSYLLIRGMKTLALRMEQIERNALAVVEMLNQHDKVTKVYHPSQPSH
                     LNYDVHQAQADGTTGIISFEVADVEKAKFLVRQTKYFTLAESLGAVESLISVPSLMTHA
                     SIPADIRAKEGIADGLIRLSLGIEDTDDLVEDLKQALDQL"
ORIGIN
        1 tcgtatcgtt gttggattga atgtatgatg ttgaccttgt tgacgccatt ggaatgtgct
       61 tcctgggtct aacgtgtcac ctttaatcgt ttggcgcgcc ttgttttcag cgtctaatgt
      121 ttcaatggag atgcccgata atttagaagt tgtgcccgta aaataatcgt taatcactgc
      181 ttctgataac cctaccgctt caaagatttg cgccccttga taactttgaa ccgtagagat
      241 acccattttc gccattactt taatcagacc ctctgataaa atggcgttgt aacgcgcgac
      301 gttatcggct actacaccgt ctaatctacc gtgctctgtc aattgcgcaa tcgtttgttg
      361 tgcaagatac ggaacgactg cattcgcacc gtaaccgact aaacaagcaa ggtgatgcac
      421 ttcacgtgtt tcaccagaac ttgcgacaat gctcgtttgc atccgtaaat tttcacgaat
      481 taataattga tgaatatgac tcaccgctaa taaaatcggc atcgcatact ggtctacttc
      541 ggtgacgtca ctatcattca acacgatgat ttctgcccct tgacgtaccg ctttgatgac
      601 cacttcccct aagttgtcta gcgcttcttt taatccacct atgtaacctg tcgaaaactc
      661 tgctaccgta aagccttctt gtccgatgac gtctaattgt gctggtgtca acacgggatg
      721 tttcagttgc acccgcttga ggacatccgg ccctggttcc agcaagttgc cttctttacc
      781 taaataactc aattcactcg ttacaatttt ttcacgatat gcatcaatcg gtgggttcgt
      841 tacttgtgca aagagttgtt tgaaataatt aaacagtgat tcaggtcgtt cgctgagtac
      901 ggcaagtggt gcgtcgtaac ccattgcccc aataggatct ttgccacctg tcacgagttc
      961 agttaaatac ttgtccaact cttctttcgt atagccaaag cgttgttgca ttttaagaac
     1021 atggcctaca gcgacaggtc cacccgcata tgagaccgct tctaaatcga gcttgtgttg
     1081 atacgtttcc aaccattcca aatagggttg ctgctctgca atcgcggttt ttaattcatg
     1141 gttttcgata accttatgtt gattaaaatc gacaagcaat agcttacctg gattcagttg
     1201 ccctttaaat acaacatctg cttcgtctac atccacgacg ccgacttctg atgaaaagac
     1261 gatttcattt tgtttcgtaa ttgtataacg gcctggtctc aagccattcc gatcggttaa
     1321 agcccctaac ttgtcaccat cacagaatga aatcatggtc ggtccatccc acggctccat
     1381 taaatagcta taaaattcgt aaaatgcgcg tactttcgga tcgttacttt cgttatacaa
     1441 ccacggttct ggaatgagta acatcgctgc ttgttcaggc gacatcgcta aacttaaaaa
     1501 ctctagtgcg ttatccacaa tagccgagtc actgcccgat tcatccaata tttgatggac
     1561 tttatgttgc gcctcgccga aaatcgtttc aattaagcga cgttgacggg cacgcatcca
     1621 gttcacatta ccttgaatcg tattaatctc accgttatgc atgagcaagc gatttggatg
     1681 tgcacgctcc caactcggaa atgtattcgt actaaaacgc gagtgtaccg aaccaaattt
     1741 cgatacgtat gactgctgtt gtaaatcgac atataatgat ttaatttggt ctgaacgcaa
     1801 ccatccttta taaacaatgg tacgtgtcga taaactcgta aaatataaat ctaactgtgc
     1861 actttcacca tatttttcga tttgcttacg cgcaaggtac aatgcacgct taaagtcttg
     1921 agcactctca tttacgacga agacttgttg aatgacaggc atcgtttctg ctacatgcgg
     1981 cgcgagacac gtcacgtcga ccggtacttg acgatcaccg atgatacgca acccttctcc
     2041 ttcaaaaatt gatgccatta ccgctgcatg ttttgtgtca gaaatcatga cgttggcaaa
     2101 caacatacct accgcatagt caccttcagt cggcaaatca aaatcagtga cttctgagaa
     2161 atattgataa ggtacttctg tcataatgcc tgccccatca cctgtaatac catctgcacc
     2221 gatacctcca cggtgatcga gacggcgtaa catttctaaa gacttttcga caatctcatg
     2281 agaacgttca ttattcatat tcgcataaaa gccaatccca caagcgtcat gttcttcacg
     2341 actgtcataa agtccgattt tggaatttaa ataattgtta gacatttctg acacctccct
     2401 ttagtaatat ttcaactata tagcaaagcg atttatcaca tcaatatata cttgagatga
     2461 aatctatcta attttgagat aatataaatt gtaagaggtg gaatggtatg gaattgaaac
     2521 aactcaaata ctttgtcgaa gtcgcaaaac gtgaacatat ttctgaagca gcactcgaat
     2581 tgaacgtcgc acaatctgca attagccgtc atattcataa tttagaaaat gaactcgaaa
     2641 catcattgtt ttatcgtcgc gggcgtaacg tatttttaac cgcagaaggc aaacagttgc
     2701 ttgaatatgc aaaacaaatt cttgagcaag tcgatctcac tttgtcgcag tttcaaacgc
     2761 aagtacaaca acagcaaagc gtcttcacaa tcggttatgt ggacggctca atcggccaaa
     2821 ttttaccgca agtgttacag acaattgaaa acgagctgtc cttgtcactc attcctacat
     2881 tgttagatga acaagagaca ttacaagcgt tgcgagcaca agaaattgat tttgcactga
     2941 caactgtcac aacgacggat ccaacatttg aaatagtgcc attagtagaa gaaacgtacg
     3001 tcttatatgg ggacttacac gcaccaatga tgaacgtgcc gaatccaccg ttatcacaca
     3061 tattgaaaca accgttatac ttgcttgaac cgattcctac agacttcaaa acatatttga
     3121 taacacatgc cgacaaaccc gtccgtgtct tgaatcaaga acaattcgca cgctttattt
     3181 tacgcaatca aaaaggcttc gtacttgcac caacgtacgt caacttatat agtcaaaatc
     3241 aacaatggaa aaagatttca ttgtcacata cagatttcaa aaaaacgtta cgcctcattt
     3301 atcgacgcga tttacaaaaa cctttacgtg atgaagtcat ccaaatcatc atgacacata
     3361 tacaacaacg ttcggtttat cattaaggag aatgatttat gaagcaactt tcgaaaaaaa
     3421 taaacaccat tgtcatcgtg gtgagtatca tcgtagcgat ttgtgcgata gtattcacac
     3481 gtttgaatag ttcgttttat catatcccgc tcggtgaagt gacgaaaatt gaaagtcatc
     3541 accaagaaaa atcagtagat gaacaacata atcaagatgt gaaatataaa gacgtgttac
     3601 aagtcaaatt gttaaataca aaacaacaag gcgacaccct tcacgtcgaa caccggtata
     3661 acgcctcgaa aactgaagaa caagcgtatc aaccgggtga taaagtgcta ctgcacaaag
     3721 gaaaaaatca aaaagataca tatattattg agaaaaaacg cgataccgta ctcgtgacag
     3781 tcatcagcgc gttctttatt gcattactca ttgtcgggca acggatcgga cttcaatcca
     3841 tcctatcact cgttattaac gcgtttgcca tcttgttagc cattagtttg tatcacgcgt
     3901 atccgcaact gaatctcttt ttattaatga gtctcgcagt catgattgcg acgattttga
     3961 cactttggct cgtcattggt tggtcaatgc gtacgattgt gaccattgtc agcactttac
     4021 tcggcacgtt catttgtatt tttatcgcat ggagtgtcat cggtttaaca cacgggcaag
     4081 ggattaaata tgaaacgatg agctttctca cgattcaacc tagaaccgtc ttccttactt
     4141 ccgtcatggt tggaacgctt ggagcagtga tggatgtcgc cattacgatt tcaagcggga
     4201 tgtatgaagt gctaaagcgg tcgccacaca tttcaatgca acggtgggtg ctcgcaggcc
     4261 gtaacatcgg tcgtgacatt atgggaacga tgacgaacat tttattattc tcatatcttg
     4321 caggaagttt accgatgctc ttactttatt taaaaaatgg caacacgctc acttacagca
     4381 ttagcatgaa ttggtcctta gaaatttccc gggcaattac aggcgggatt ggcatcgtct
     4441 taactatccc attgaccatt tttctcatgc gtttatggtt aagcctacga ggaggtgcaa
     4501 cacgatgaat gccattgtca tcttaggttt gattcttttc atactcatgc tcatatttgg
     4561 cggtaaaaca ggactcgttt catttttaac gctattttta aactttatca ttttattcat
     4621 tactgtactc gccatcgttt ttggcgcacc gatttatgtt gttactttca ttttttgtat
     4681 tattgtctcg atggttaact tgtttttact caaccgcttt aatacaaaaa ctttagctgc
     4741 atttatcgcg agtacggtca cgacattatt aatgattgtc gccgtttact tgtccgtaca
     4801 ttggggtcat ctacaaggct tcacccaaga agaacaagac gaaacgtata tcttctcctt
     4861 aaatattggg attgatatgg aacagtttat gatttttact gtgctacttg ctgtcattgc
     4921 agcagtgatt gacttggcga ttacgattag ctcacctgta tttgagttac acgagacgaa
     4981 cccttcatta tccgaacgcg aactgtttca ttcaggcatg cgcgtcggcc gagaaatttt
     5041 agcgacgtct gcaaatacga tttatctcgc attgattggg ggttcaatga caattgtttt
     5101 ttggtttttc aacttgcatt acagtttcgg ccatatgctc aacgccaaat tatttgcaca
     5161 agaagtcatt acaattgcgt taggtggcat tgccattgca gtctgtattc cgattacggc
     5221 tatgataacc gcttggcttg taaaacatcg tcatcaactt ccttttcatc tagactgagc
     5281 ttcaagccga gtgaaaacgg gtacaatgtg aacgaggtga atttatatga cagcgattca
     5341 tattcatggc gcacgtcaaa acaacttaaa aaatattgac gtctccattc cgaaacatca
     5401 gttaacggtc gtgactgggc gttcaggatc tggcaagtct tccctcgttt ttaatacgat
     5461 tgccgctgaa tccgaacgac tattgaacga aacctattcg agttatattc agcaccaatt
     5521 aacgcaatat gaaaaaccgg atgttgacca tattgaaaac ttgcccgtcg cgatggtcat
     5581 caatcaaaaa agactcggtg gcaattcgcg ctcaacggtc ggtaccattt cagacattta
     5641 tgcgtccgtc cggctattgt ggtcacgtat tggcacacct ttcgtcggtt attcagacgt
     5701 cttttcgttc aataatccga atgggatgtg tgaacattgt caagggcttg gttatgttga
     5761 agatatcgac ttgaatgaac tgctcgattt cgacaaatct ttaaatgaag gtgcgattcg
     5821 cttcccgtca tttaagccgg atagttggcg cgggaaacgg tatcgctatt cgggtttgtt
     5881 tgataatgat aaaaagctca aagactatac aaaggaagag ctcgatacgt ttctttatac
     5941 cgagccgaca cgcttgaaaa atccacccgc agaatggcct aaaactgcaa aatttgaagg
     6001 gttaatccac cgtttccgac gctcattttt aattaatgat aactttgaaa agaaacgctt
     6061 tttaaaggac gttgaacgcg tagtcaccaa gcaaacatgt cctgtctgtc acggacaacg
     6121 cttaaatcaa aaagtgctca gctgcaaaat tcatggcttg aacattgccg attttacagt
     6181 actgacgatt gaagaaacgc tcccattttt agagcaaatc gacagcgaca aagcgactta
     6241 tattatcgaa ccattgaaag cccaactcca agctttgaat gatattgggc tgaactattt
     6301 aacgctcgca cgtgaaacaa cgaccctttc tggcggagag tcacaacgga ttaagctgat
     6361 tcgtcatttg aacagtccgt taaccgatct cgtgtacatt atcgacgaac cgagtgtcgg
     6421 tttacatcca gcagatattg aaaaaatcaa cgaaatcatg ctcaatatcc gtgacaaagg
     6481 taataccgtc atcatcgttg aacacgatcc cgacgtcatc aaaattgcgg atcacgtgat
     6541 tgacatcgga cctggcgcag ggaaacatgg cggccagatt acatttgaag gcagttatgc
     6601 acaacttaaa cagtccgata ccgatacagc gcgcgcattg acacgtcaac atcacttgaa
     6661 acagtcagcg attcgtgaca accaagcatg gttacactta gaacatttgc aacacaacaa
     6721 cttacaagat gtgtctgttg cgatcccgaa aaatgcgcaa acggttgtaa caggtgtcgc
     6781 tggttcagga aagagctcct taattaaagg cggttttgcg aaacatgaag atgcgatact
     6841 cattgatcaa aaaggcgtac acacttccaa ccgatcgaat ttattaacgt acacgggtat
     6901 tttcgatgat attcgtgagt ttttcagtaa agcaacagga ttgaaaaaaa gtatgttcag
     6961 ttataactca gatggcgcgt gtccaaattg taacgggaaa ggcgtgctca aaaccgaact
     7021 cgccttcatg ccagacttct cgcaagtatg cgaggtgtgc ggagggaccc gctatcgtcc
     7081 agaagtgttg gaaacgaaag tcgacggtta ttctatcgcg gacgtgttag cactcaccgt
     7141 tgaagaaggc ttgtcacttt tccaaacaca tgacgccatt gctcaaacgt taagcgcctt
     7201 gcaatcgaca ggactcggct atatgacact cggccaatca ctcgacacct tatctggcgg
     7261 ggaggttcaa cggctcaaac tgacgcgcta catgattgag cctgttacag aaaaaatatt
     7321 tattttcgat gaaccgacaa caggtttaca tgaagatgat atcccaattt tacaggcacg
     7381 cttcgatcaa cttattgaag aaggccatac cgtcatctta attgaacaca atatcacgat
     7441 gatgacacga gcagactggc tcattgacgt tggacctggt gcgggaaatc aagggggacg
     7501 cattctttat agtggaccac ctgcaggcct aaaaaacgtc gccgaatctc gcaccgctcc
     7561 ccatttattt ggtagtttat cggaataagt ggtacattga gtatggggct aggacataga
     7621 ccttcagctc ctttaagaaa aaaaacgtca aaattcaatt tttagaattt gatggctttt
     7681 ttcttatgag cgaacgaaaa cgagcactga ttttggccag ttttcgtata tttactgcca
     7741 tgagtgcgat gccaagttca cactcaactt ttgattgggt gcgaaccgat aatctttgga
     7801 aacccaaatt agctttcaga tttacaaaag ttgattccac atctatcttt ctcttttgat
     7861 aaatgtgctt cgtttttgga tctgaaagct tcttatttat gaaggcttta aaataatccc
     7921 aagttagatt tttaaataaa cttttatttg tgttagactt tgtactttgc ttcatacatt
     7981 aacttcgtaa tggacagccc acacacgctt cacatgcata taatttaaaa tctctttgaa
     8041 taccgtatcc atctcttctc tttctgtaac tctggaaatg taatgtcttc ttattcggac
     8101 atatgtaata atcttctatc acgttgtatt cccagtttgc agtaataaat ggattgtttt
     8161 tatatttacg ctgcttctct ttgaggtaca tactataagt gattaaaggt gttttctcaa
     8221 attcatcgag tatcacggta tagttgtatt cacttccgta acctgcatct gccacgatat
     8281 actctggaat gtcaccatat aatttgtgaa ttgattttaa aaatggtttg agcgttcttg
     8341 tatcacctgg ataactataa acaccaaaag ctaaaacgaa ttgattattg gtagctatct
     8401 gtagattgta acccggtttc aactcaccgt ttctcatatg gtcatctttc attctcatga
     8461 aagtcgcatc atgatcagtc ttagaataac tttttctgtc gccataaatt tccatttgct
     8521 tgtcatattt taatttacgg tccttaaaat cttggatagc cttcttactt tgtctcacgt
     8581 tacttctttc ttttctaagg ttttttcttg tctctacatc ttgagttgtt tcaatttcag
     8641 acgtgagcgc atcattttta tgacctaaat gcgtctctat ttgattcagt tcttcacttg
     8701 ttaattcatg tccagattca cgcttgattt caggaataat ctcttcagaa acgagttgtt
     8761 catataatgc cgttgatttt tcaatgacag actgactaaa acgcttcgta ttagccagcc
     8821 actgaaatgt atacttattc gcattggctt ctatttttgt gccatcaata taaatgacat
     8881 cctctgtaat gagttgttct tctaataact gtgctcttaa accgaatatt attacacttc
     8941 aattattaac ctcttcctta aataatttat tattcacatc tcacaacttt agcttttaaa
     9001 ttcttccttt caggctatag tttatcaaaa aagaatcaaa aagttttgca aacgaagcta
     9061 ttacatcctt cacatgggat catttgtttt atctcttcta aagataatat ttttataaag
     9121 cgagaagacg tatctacaat ttttctatct tttaattgct tcataattct agcgatattc
     9181 tctctcgtag ttccacaata ttgagctaat tcttcttgag tgattttaat ttttatcaca
     9241 atcattctcc cttcttcttc tccaaatgta ttagctaatc taactagaat agatagtaat
     9301 ctacacactt tgtctttagt taacatatct ctaataaaca tatctttttt cacattttca
     9361 tttatgagta attttatgta ttctctacaa attttctcat catttattat gctgcttata
     9421 agcattttat aaaatacaac ttctgttttc ccacaaaagt atttactatt atcacaaatg
     9481 aacaaactat ctggccctat gattttataa atcaaagtag taccatctat gttatcttga
     9541 tgtacatata atataccctt atctactaga tatatatttt tttcaaaatt ctcttgaaaa
     9601 tactccccct tacacaactt attatttatc cctttttctt tgataatctc tttaatccct
     9661 agcaactcta ccataacacc ccccctttat aaaaaattat accatttaaa ttacttttag
     9721 taacatgcgt tacaaaactt ttgaataatt tatattaaaa tgtgtttgta gttaaataaa
     9781 ataaaggggg ataccaaaat ggaaaaaggc attatggtaa gtaacaaggg ttgttcgact
     9841 tgttcaattg gagctgcttg tcttattgat gggccattac ctgacttcag aagtcatggg
     9901 aattactgga atttttggac taacttctta gcactgtttg tatgccggca aaatgatagg
     9961 atttatcata gtttgtcggc gtacttttta ttaagggggg atagaaatga atcaatatat
    10021 attttttaat gacaatgcta ggttgcatca attacctcat ggtggagtaa ttgaggtgaa
    10081 aaatggcatg tttaaagatg aagtgttcga ctttgaatat ttagatttaa attcttctgc
    10141 tttcgaggca tgtacgtatt ttgatggttc catgacaata atagatattt taaaagatat
    10201 gtgccaaaaa tataaatgtg atattaacga tcacatagaa tggtatacaa atctagttaa
    10261 cgatttgtat aagaaaaatc ttattaatct cgttagtaat cctgttaaaa aaaaccttaa
    10321 tattagcgga tcaactgaat atattacacc actacatgcg gtgtttgaaa ttacacataa
    10381 atgtaattta aaatgcgcac attgttatct agagtcttca cctcaagttc aagatacgct
    10441 ttcattagat gaatttataa tgattgcaaa taatatgtat gaaaatggaa ttctaacatg
    10501 tgagatcact ggtggagaag tgtttgtaca tccaaacgca aaagaaatat tagaatttgc
    10561 actcaaaaag ttcaaaaaag tcggtatctt aacaaacgga acactgttaa aaccagatat
    10621 tctcgattta ttaattaaat ataagaaaaa aattgttata gggatttcat tagatagtgt
    10681 tgaccctgaa aagcacgata attttcgtgg caaaaaaaat tcatttaatc agacttgtaa
    10741 aaccattaaa aaactttctg aaaatgggct ttttgtaagg gtcggaatgt ctatttatga
    10801 ggataatatg tgggaaatca atgatatggc gaatttagta agaaaactag gagcttcagc
    10861 cttttcttat aactggatag atgactttgg tagaggtaaa aaaatgaatc agttgaaatt
    10921 gaataaacta aacaacttgt cttttgctga atttgaagtg gacgttgtta aaaataatag
    10981 ggacattata ccattagttc ctctaactaa aaacaaagcc aataattgtg gggctggctg
    11041 gcgttcaata gtcatggatc ctaatggaaa tattcggccg tgtgcactat ttccaaaaga
    11101 atttgtaatc ggtaacttaa aagaacagtc atataaagac gttttctcct cagaaatagt
    11161 aaatcgatta tactctctgc agtctccaca aaaaagtaaa ttttgcagtg atgaatgcag
    11221 cttcaaagac tactgcgctg gctgttactt aaaaggtctt aatagtaaca aaaaccatcg
    11281 gacgaattac tgcggttggg ttaaaaacca aaaattagaa aacttagtag aacaaatata
    11341 aaaggagata aaacatgaaa agagacttaa ttacaataac cattgctata atttttttaa
    11401 tatctagtgt aatattcgcc attaagcaag aatgggtttt cgcagtaatc ttcatattga
    11461 tagggattat ctatatatta aaaacattta aaagaggtaa atctaatgat gagcattcat
    11521 ctaaataact tatgtatttg gtatgagcca gaaaatttaa taattaaaaa tgcaaatcta
    11581 tacttacaaa aaggaaaaat ttatggattg cttggaaaga atggatctgg taaaacaacg
    11641 ctaataaata ctatatgcgg ggttatacca agtttttcag gagatataat cattaacaat
    11701 ttgaatatat caaaatttaa ttatcaagct aggttagaaa gattttatgt accagatagt
    11761 ccccctgtta tttctcaaat gacaagtaaa caatatataa gttttgtttt aaatatgtat
    11821 caacaaactt taagccaaga gcatttattg agaatttcta aaaaatataa ttttgaaagg
    11881 tatttagata taagaatgaa tgagctctct tttggaaata aaaaaaaggc tgctttaatt
    11941 tgttcaatct tattagatgt acctatcaaa atattcgacg aaccattaaa tggattagat
    12001 atagagtcaa tagatttgtt tgttcaagat cttttcaaaa tgacaaaaga agataaatgc
    12061 gtcatcctat cttctcattt attagatatt gtaaaaaagc tgacatctaa tattatatat
    12121 attaataata aacattgttt tcaattcacg cttaacgatg aaagcgatat aagaaaggtt
    12181 ctatctgatt atgataaaga ataatggata tttaattcta ctctattgct attactacaa
    12241 taaacttaat ctaagagcca taattagaaa ttcactagga atagcaattc ttttaatatt
    12301 tgaatacaaa ttgattgaaa gtcatttgga taatgtcaat ttgttatatt ccaattatct
    12361 aagattatct atcatattct cctcaattat attgactaat atttactgga actctttccg
    12421 cgaaagcgag ttatatagac tcttagggta catgcctatt aataatgtaa aggttttaat
    12481 aattctaaat gtatatattt tcgttgagat aaccgggaga agacttgttt ttttacttgt
    12541 actaccattt tatgttttgc taatcggcaa attcagtatt tacgggagca ttttgacatt
    12601 ttcattattc atactactga ttgtatcttc tcaacttatt tgcattcttt tgcatgaatg
    12661 tgaaaagaga catgtgacaa tttcattact tctagcactt tttttaagcc cattttttaa
    12721 taaatttata agtttggtgc ttttaattct tgtattatta ggtgtatcca tctttactaa
    12781 ttttataaaa tttaatgtaa aaaagagaaa aaaacctaca aaagctacag taaacgaaat
    12841 atcgatttta aaatgggagt ttaaaaagtt tttcatagaa aaaacaaatg tcattggaat
    12901 aataagtatg ttccttttcc tcaatatttt aaactacaat attgaaagta tagatggaat
    12961 gacggtagag tttggactaa agtatttttt gatattacta attatttctt caataagtcc
    13021 attaaattta atgttttcat ctgataaaga attaagaaaa attgctactt atatgcctgt
    13081 taaaaagcga agtatcttta tggctaaaat tttagtttca acattaatat cacagttttt
    13141 tctttctatt gtagtgttca taaacgaaat gctattccaa gaaaagttag gcttactata
    13201 cttcaaagta tctattttgt tgtttttttt aacttttttg agattaaaac ttgatatgat
    13261 aaagcccatt ttagattatg aagataaaat ggaattgtgg agaaatccga aaaaatactt
    13321 atcattgatg atagtgatcc ctcccctttt tgtagctgta gcactaaatt tttatatttc
    13381 tctagttatt atattatcag gttgtttagt attagaacta tatagtcaac tttatggaaa
    13441 ggaagatttt tttggatata aataacgcta taaatattta taaatatcac gtctatatca
    13501 ataaaataag tggcgttgaa aatttcacta ttaatcaatt gatttctgaa atattaaatg
    13561 agaaattcaa agcattaaat gattattcaa ttattcctta tactacaaca agtgttttgg
    13621 gaaaagactt ttataatatt ttttatctaa aaactttaag aaaccggtat gtagacctag
    13681 attataacta ttggctcaat agtttttata ataattttca aatgtctgac aatgagtgtt
    13741 acttagcctt ggaaaaactt attaataaaa ttaaaaaata tcagttaaat ccaatgaata
    13801 tcaataaatt attagtaaaa gacaaacttt acccaaattc attattagga agtaaacgtt
    13861 tagggactat tgaaacatta aatatgaatc aaataagtca agagttagta ctacaaagaa
    13921 tacccgaatc tatatatgca tataatttat gcatctcaaa aattaaagga gagctaaata
    13981 tacataaatt acagaatatt aaatatgcat ctcctttttt tataccacat atagtaagcc
    14041 aaaaagttcc accattaata aatggacaaa gtattaacac aatttgttat tattttgaaa
    14101 gtaatgatga atattcaaaa acaatttatg gtcctatgtt acaaggctac ttgacgcaat
    14161 atggccattc aatattgttt aaaaagctaa ggatagaaga atttcaatta tatcattttg
    14221 aagctcattt tgatcaagaa actaatatcc tattcatcca atacatagtg gatgaaaatt
    14281 ggaaaataaa agtttggaat ttaattatat ctgaagttat ggatttaaat attaataaag
    14341 aagagttcca gactatgaaa atcttcctat caaatgaata cagatttaaa ttcgataaat
    14401 catttggaga attgaatcac attcttagtt taggaaataa atttttacaa tcaaataata
    14461 tatttaaagc tatccaagat ataaaaattc aagatttcat caaatttcta gataataaaa
    14521 aaatgataaa tattgtatat gagggatgaa aatgaaagtt acaaaactat tttatgcaga
    14581 tttagatcaa aatctttaca atctatttca aaacgaaata aaagtaacat actttaataa
    14641 gagtgactca tatataaatc aaattaaagc agtcgtaaat atcgggggat atcaatatca
    14701 aaccggagct gctcatttta tagagcacct aaaattttgg aaagaaaaca ataacttata
    14761 tgatttaatg aattactttg gcactataat gaacgcaaat actacagaat atgaaactaa
    14821 ttttttactg tactgtagta aggaaaatac ggtttctact ttgactaatt ttacatcata
    14881 cttattaaat cacagctaca ctattgaaga atttaataaa gagaagaaaa taatattaaa
    14941 tgaggttaaa ggataccatt caattttagt ggatgaaaat gaaaaattag aatatgtaaa
    15001 aaagataata ggcgatgaaa atcaaattaa tgacatttct aagagatatc tagaaaacct
    15061 atcttcaata tgctatcaaa aaagaaatat tcactattat ttaataggtg atttttctga
    15121 atatatccat aaaagcagag aaataagcaa ggaaaagata gagctagtag taaacagcga
    15181 tcttattata catgattatg ataatactga attgtttttg aaaacccttt atttccatat
    15241 aaataaattc ataaattatt atttccagaa caaaagcctt gtggttaatt tcaataaatt
    15301 atataatacc aaaaaaattc atgatatgca gttagatgat tttataagtt atataatttc
    15361 ttatatagta aatgtttatg aagattctga tttgttaatt gagtttttgg aaaactggaa
    15421 attcacaagg ggagatttta caaaaatcgg taatttactt gaagatcaag aaaagttatc
    15481 tatattatta aatgaggcat tcatgtgaaa aaaacaccta ttgtattatt attcactttc
    15541 gcgatagtat tagaattatc tccccttaaa agtcatttag tgaaattatt gataaagtcc
    15601 caattattaa atccgtattc ttggtctagt tttcttttta ttacactgct tttttcaatt
    15661 attttaaccc caattcaggg tgttttttat agttttaata ataaaatgca aatagttaat
    15721 agtgtatata taaaaaataa gtttaagatg accgaggaag taatagaaat tagtaaaaaa
    15781 ataaaattac ctaccaagaa acaagtgttt ttaattctcc taataaatgt aataacgtat
    15841 gatgtcttta ttagtatcct ctcaggattt aaattaaaca cacctctcgt tgcatttatt
    15901 cctatcggta ttatttttat gatttctact tattttttag tgtatagatt ttgtaaacaa
    15961 agaataaatc ataaaatcct gattttttta atgtcaatca ccttttcttg cgttattcta
    16021 tcatatgtga aagaagagat tgtgatattt atagtaatag agattattgt tttttatctt
    16081 tataatatgt ttttaaaaat tattaaaaga taattacaaa gaactactct gtatataact
    16141 tttcagtaaa actaattaca ttgactgtag gcaacgttac aatgatactg ttaataattt
    16201 tacaaataca tttaaactga atcttacaga cgttatagtt gtccctaaaa tccttactca
    16261 tcatttataa atagcgattt tcattaaact ttaataagat aatccttgta aaaactccct
    16321 ttataggggg gttgttgcac aattgttttg attattaata tagaaacact gtatttctta
    16381 caatcgcctg caaatacaca gcgtctcgcc aagtctattg cagaagctga acaaagccac
    16441 acgattgcat taaattgaaa tacttaaaca agctctcatc aacgcaaaaa ctccgagact
    16501 tccgtcatcc attgacgaaa agtctcggag ttttctttta cttaacgtgt cacacactca
    16561 atcttaacgg ctctcttttg ctttaatcac aattgagtta cctgagtaaa atgcgacatg
    16621 tgttgttttg gcatcataaa tttcgccttg tttcacgtga tcgcgcacag atttgtcact
    16681 atgattaatt ttttcaatca ataatgtcat gttgaccaat ttgccttcgc tattaatacc
    16741 gaagatgaca tcatttttct cgtagtaagt gacacctttt tcttcataat attttttcac
    16801 gtcgttccct accgcttttt taacgtcagc gaatgtagac tggccgactt ttaaaccttc
    16861 atatttaaag ttatcgtgtt gtaatgcgcg gtaaaagttg ttgtcctcta aagctttatt
    16921 ccctttgaag ttaaataagc cgttatatgt gtaataaggt gtttgctgtt ccgttgcggc
    16981 atgtgcatct gcatggattg cacttgcccc agctgttgct cctaataatg tgcctaatga
    17041 taaagttgtt gcgactgcaa tttttgtaac ttgattcatg tgtaccactc ctctttctct
    17101 cgatactgtt ctaaaaatta ggaatttatg ttatttgtaa ttgtcgaatt aaatttccaa
    17161 tttataataa cttatatatc aaattgttcc ttactcgaat gataacaaat taagataaca
    17221 ttttcatcca aaagtttttc ggtcattgga ctgaaatttt tctacaacgc tgtatctaaa
    17281 agacgtgtta acaatcattt aaggaaagtg catatgttgg gttttgacct atcagtaatg
    17341 ttataatgaa tgacatcata ctatattcat tgggggaagt ataatggcta aaaaatctaa
    17401 aaaatcatta agtgtgcttt caactgcttt aacaggcgca acattagttg tagactttta
    17461 caattcttac atttatcgct caaaaaatcg caagctaagc tatatttcag ttgggcttgg
    17521 cttagtagat gtcgtattaa gcttctattt atcacttggt gcaaaaagca aattcacaaa
    17581 agcatggtct ttcttctcag caagtcgcca agtatggagt ggtatccaaa aaatccaagc
    17641 gattcgcaca cgtgggtagg gtaacgactt gattcatttt caaatcatta aatataggcg
    17701 tgaacatgaa acattatgat ttctgttcac gcctttttta tgtagtagtc attgcccaga
    17761 tgctcaagtc gttatatctt cgcttcatcc aattttttaa agctaatcat taaagcatcc
    17821 gtttctgtga atatgacgat acaaatggat tgactcaacg tctttatcct tacctaagaa
    17881 tcatcgacaa gatgtttgtt accattttgt taatagaata tgacatgcat ttcaaacttt
    17941 ttgggatttt ttcaaatgac gaaaattttc tcattcgacc cttgtcttaa aaaataaaaa
    18001 cgtgagcacc atgtaaaagg tatactcacg ttttttgatt aatggatata tttgaaggca
    18061 cttacacgat gcgctggtac agtacggtaa gtgagaatgc ctggtgctgc agtgaaattc
    18121 atttctgata cgagtatact accatcagca ttaattcgct ctacatacga aacatgacca
    18181 tagtaaccta agtcagattg taagattgat cccactgcgg gttggttatt aattgtataa
    18241 ccatcacgtg cagcgttatc atcccaagca tttgcattcc accagtatgt actgattggg
    18301 cgccccatct ctttacgctt attaaatacg taccatgtgc attgacccca atcgtataag
    18361 ttttgatggt tgaatgtagg agattgataa cttggacttg gtgtcggtgt tgtttgacgt
    18421 gacggtgccg atccactcac ttttaattgt tgacctggga aaattaagaa ggatgttaat
    18481 ccatttaact ccataatatg ttgatatgtt gtaccatatt tagacgcaat caacgacagt
    18541 gaatcacctg gttgtactgt ataataactc gcatttcttg aagacgtttt aggtgccggc
    18601 ttcttcgctg tggaacgact tggtgttgta gacggaccac ttacatttaa cttttgacct
    18661 ggtaaaatca agaagttgtt caaaccgttc catttcataa tgttttggta cgttgttcca
    18721 tatcgcgctg caatgcctga taaagtgtct ccgtaacgta ccgtatagac tgttgatgac
    18781 gtagtgctat ggcttgaatg atgagttgtt gtgcgtgatg tactgctacc accagaaacc
    18841 ttcaacactt gattcggaaa gattaagtta gagtttaatc cattatattg tttaagttgt
    18901 gctattgtga tgttatactt tgttgcaata gcccaaagtg aatcacctgg ttgtacacga
    18961 tacgttgttg aagcgtctgc atgtgctgat aatgctgtgg cagctgctgt tgttcctatt
    19021 acggctgcga taaacttttt acgcattcgt ttccctcctt ataaaataga agatattatt
    19081 cttatacagt tttatattat acaccgatta tcatgtagaa atatgtctgt tatataacat
    19141 tatgattaca aaaaccatca tggcggtctt cagaaagtaa atatatttac acatgcttat
    19201 ttgagaatta aaataatagc tatcatatta ttcataaaga catttttctc ggatatttct
    19261 tttatttatc tttcgtaatt gtaaaatatt tgaccacttc atcattgttt atggaagtaa
    19321 acttatgcat cacgataaag cttgatacga cctttttaac attacaaggt gcgatttcgg
    19381 tcgttaaaaa cttatgccaa aaaataatac caagatgatt aaaggtgtca aaacaaatat
    19441 attaagtaaa ttgatgataa accaaattaa gcctactttt tgtaacttcg catcgtctgc
    19501 gtttaggtgc cacaatgaaa atatgcccgc agctaatgac gttgcctcaa aatataataa
    19561 taaatcacca aacgctaaca tcaattgcac acaaatcagt ccacctacta ttaaaaataa
    19621 gtaattcaaa acattcacga tatacacgac tctgatccta ttcatttatc acgactcctg
    19681 ttgaaagtcc ttaatatggt ttttcatcat actataaacc taggaaacaa ttctgtaact
    19741 tatcaaaatt ataacatttt catatgattg tgattatata tattagtttc atacttataa
    19801 aaaagtgcgt gcatgaagat aggacataaa actttttggc gctactgcta ccgcattggt
    19861 ttaacttgta cgcttccagg acttgtctta actaaatcca gtgtccacga gggccatttt
    19921 catttgttgc gtatatcaaa aaagtcatgc catgttcaaa acgagacatg gcatgacgct
    19981 gtcgaatgtg attgatttta taaacgaaat tcataaggat ttgaggaaga ctttaacttt
    20041 ggtactagct actgtttaac gcagtagctg tctgacttct caatgcttgt acttgtgaga
    20101 agccgagtca gccttgcgca ggcatttacg acgaaatttt tgttgcacaa gaggtttctg
    20161 tacgactccc tcaaccccat gtcacttaca attgatcaag tgcttgtttt aaatcttcta
    20221 caagatcatc tgtatcttca atacccaatg ataatctgat taaaccatct gcaatgcctt
    20281 cttttgcacg aatatcagcc ggaatcgatg catgtgtcat taagcttggt acagaaatta
    20341 aactttcgac tgcacctaaa ctttctgcga gtgtgaaata ttttgtttgt ctcactagga
    20401 atttcgcttt ttctacatct gctacttcaa atgagatgat gcctgttgtg ccatctgctt
    20461 gcgcttgatg cacgtcgtag tttaaatgtg acggttggct tgggtgatac actttcgtca
    20521 ctttgtcatg ttgattcaac atttcgacga ccgctaatgc attacgttcg atttgttcca
    20581 tacgtaaagc taatgttttc atcccgcgaa taagcaagta gctatcttga ggccctaata
    20641 cgccccctgt tgagttttgg acgaaagcaa tgcgctctgc gagtgtttcg tctttaactg
    20701 cgacaagtcc ggctacaacg tcactatgcc cacctaaata tttcgtcgct gaatgtacaa
    20761 caatatctgc gccaagagac aacggtgttt gataatatgg cgtcataaat gtgttatcca
    20821 cgacagtcat gagttcgtgt tgcttgccga tttcactcac cgcttggata tctgtaatgc
    20881 gcagcaatgg attagatggc gtttcgataa ataacatttt cgtattatct ttaatcttat
    20941 cttcaatatt ttgaacatct gtcgtgttaa caaagtcaaa ttcaatacca aaacgtgtga
    21001 agacacgtgt cattgcacga taagagccgc catacacatc agagccaaca ataatgtggt
    21061 cgccttggtc taataacatg ataactgcgc tgatggccgc catgcctgaa ccgaatgcga
    21121 aaccgtagtt cccatgctct aaatcagcaa tgacagactc gagcgatgaa cgtgtggggt
    21181 tcgctgtacg tgagtattca aacccttgtc ttaactcccc aatcgcatct tgttcatacg
    21241 tactcgtttg ataaatcggc gtcgtcactg cacctgtata atcatctgta gtattaccgc
    21301 aatgaattaa taatgttttt ttattcattt aaatctcctc c
//
