LOCUS       NZ_CP066713            20882 bp    DNA     circular CON 14-APR-2024
DEFINITION  Staphylococcus pseudintermedius strain DSP026 chromosome, complete
            genome.
ACCESSION   NZ_CP066713
VERSION     NZ_CP066713.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2567628)
  AUTHORS   Ferrer,L., Perez,D., Fonticoba,R., Vines,J., Fabregas,N.,
            Madronero,S., Meroni,G., Martino,P., Martinez,S., Cusco,A.,
            Migura,L. and Francino,O.
  TITLE     Whole genome sequencing and de novo assembly of Staphylococcus
            pseudintermedius: a novel pangenome approach to unravel pathogenesis
            of canine pyoderma
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2567628)
  AUTHORS   Ferrer,L., Perez,D., Fonticoba,R., Vines,J., Fabregas,N.,
            Madronero,S., Cusco,A., Migura,L. and Francino,O.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2020) Servei Veterinari de Genetica Molecular,
            Universitat Autonoma de Barcelona, Edifici V, Travessera dels
            Turons, Bellaterra, Barcelona 08193, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUL-2020
            Assembly Method                   :: Flye v. 2.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 303x
            Sequencing Technology             :: Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016455085.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 20:32:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,471
            CDSs (total)                      :: 2,390
            Genes (coding)                    :: 2,301
            CDSs (with protein)               :: 2,301
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 63 of 89
            Pseudo Genes (incomplete)         :: 28 of 89
            Pseudo Genes (internal stop)      :: 9 of 89
            Pseudo Genes (multiple problems)  :: 10 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1265867
            Orig. end                         :: 1286749
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066713.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20882
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20882
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20882
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10882](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10882
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(1216..1229)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.46"
                     /tool="antismash"
     gene            complement(1431..1817)
                     /locus_tag="JGZ50_RS06010"
                     /old_locus_tag="JGZ50_06010"
     CDS             complement(1431..1817)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016425163.1"
                     /locus_tag="JGZ50_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06010"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_014613830.1"
                     /transl_table=11
                     /translation="MSNMTLIVLIVLALVIIWMVTNFIINKRSVTELNQEEFQEGIRKA
                     QVIDLREKADYDYGHIIGARNIPMTMFRQRYQGLRKDQPIYLVDANGIASYRAARTLKK
                     KGYTNLYMLKGGYKKWTGKIKSKK"
     misc_feature    1842..1855
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     gene            1968..2798
                     /locus_tag="JGZ50_RS06015"
                     /old_locus_tag="JGZ50_06015"
     CDS             1968..2798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500143.1"
                     /locus_tag="JGZ50_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06015"
                     /product="biotin/lipoate A/B protein ligase family protein"
                     /protein_id="WP_014613831.1"
                     /transl_table=11
                     /translation="MTETWHFMNTGSHHPYYNMALDEALLNFVSRGEIDPVVRFYTWNP
                     PTLSIGYFQRLSKEIDIEKVKEKGYGLVRRQTGGRGVLHDKELTYSVIVPEAHPDMPQT
                     VTEAYRVISGGLLEGFKSLGFDAHFAVPRSKEEREKLKQPRSSVCFDAPSWYELVVEGK
                     KIAGSAQTRQKGVILQHGSILQDVDIDDLFDMFIFKNERLKAKMKEAFVEKAVAINDLS
                     NETITLAQMEVAFKEGFKKALDIEFKPLELTVAQQDEVKALEEKYRSEAFLYRK"
     gene            complement(2914..3138)
                     /locus_tag="JGZ50_RS06020"
                     /old_locus_tag="JGZ50_06020"
     CDS             complement(2914..3138)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613832.1"
                     /locus_tag="JGZ50_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06020"
                     /product="SA1362 family protein"
                     /protein_id="WP_014613832.1"
                     /transl_table=11
                     /translation="MTTFQKMIFGVIIFVALIGLIFNLDVVLFSIFRSIITVAIIVGII
                     YLVYFFFFLTPDQRDYKKRVWKNKFKGRR"
     gene            complement(3159..3758)
                     /locus_tag="JGZ50_RS06025"
                     /old_locus_tag="JGZ50_06025"
     CDS             complement(3159..3758)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613833.1"
                     /locus_tag="JGZ50_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06025"
                     /product="hypothetical protein"
                     /protein_id="WP_014613833.1"
                     /transl_table=11
                     /translation="MKKRICASISVAFLLSACGSQNLLPLEKRSTDLSDKNHEIKLENQ
                     QLKNENAKKQKQVDALKKDSENTKQAKSNQKKADYLEISSQYYASVTDAINAYQQIDSK
                     VLANKKEDKVLDQLDQIIEDHESAMESYQDATEDEKIVKKDKSIKAQDKEIRKLQKEIN
                     SALTMIRKGYKAKDKNEIQKGRQSLSNINVKTTNAG"
     gene            3853..4923
                     /locus_tag="JGZ50_RS06030"
                     /old_locus_tag="JGZ50_06030"
     CDS             3853..4923
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613834.1"
                     /locus_tag="JGZ50_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06030"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_037542943.1"
                     /transl_table=11
                     /translation="MKNRLQKIRTLLQDKHLDGLTVLSDFNRRYLSGFTGTSGALIITQ
                     DKALLITDFRYTDQAQQQATEFEVILQKGDLFSALTEQFKTLNLQNIGFEGHLVAYDSF
                     LKLNQGRHDLISIGQAIETIRQTKDEGEIKAIQKAAQIVDEAYKYILTVVKPGMTEKEV
                     KAHLESKMLHLGADDTSFDTIVASGIRGAMPHGVASDKVIQSGEMVTLDFGAYYNGYCS
                     DITRTFAVGQPSEEMVKIYNIVLKSQEAAIAAIRPGMTGKEMDSIARDIITEAGYGKHF
                     GHSLGHGIGLDIHELPGLSQKSDVVLEKNHCVTIEPGIYVEGLGGVRIEDDILITENGG
                     ERFTNCTKDLIILKEE"
     gene            4942..5499
                     /gene="efp"
                     /locus_tag="JGZ50_RS06035"
                     /old_locus_tag="JGZ50_06035"
     CDS             4942..5499
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="efp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626504.1"
                     /locus_tag="JGZ50_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06035"
                     /product="elongation factor P"
                     /protein_id="WP_014613835.1"
                     /transl_table=11
                     /translation="MISVNDFKTGLTISVDNGIWKVIEFQHVKPGKGSAFVRSKLRNLR
                     TGAIQEKTFRAGEKVEPAMIENRRMQYLYADGDNHVFMDNETFEQTELSTDYLEYELKF
                     LKANMDVHIQTYQGETIGVELPKTVELEVTETEPGIKGDTATGATKSATVETGYTLNVP
                     LFVNEGDVLVINTTDGSYVSRG"
     gene            5832..6292
                     /gene="accB"
                     /locus_tag="JGZ50_RS06040"
                     /old_locus_tag="JGZ50_06040"
                     /pseudo=""
     CDS             5832..6292
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019165243.1"
                     /locus_tag="JGZ50_RS06040"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06040"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNFKEIKELINILDNSNLTEISIEDKGTTINLKKKKKL"
     gene            6294..7649
                     /gene="accC"
                     /locus_tag="JGZ50_RS06045"
                     /old_locus_tag="JGZ50_06045"
     CDS             6294..7649
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613837.1"
                     /locus_tag="JGZ50_RS06045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06045"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_037542950.1"
                     /sec_met_domain="RimK (E-value: 3.9e-06, bitscore: 23.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 8.4e-08, bitscore:
                     29.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.1e-09,
                     bitscore: 35.2, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2e-06, bitscore:
                     25.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKILIANRGEIAVRIIRACHELGIQTVAIYSEGDKDALHTQLAD
                     EAYCVGPKQSKDSYLNIPNILSIATSTGCDGIHPGYGFLAENGDFAELCEAVQLKFIGP
                     SYESIQKMGIKDIAKEEMKRANVPVVPGSEGLVNTIEDAIQTANSIGYPVIIKATAGGG
                     GKGIRIARNEEELINGYKMTQQEAETAFGNGGLYLEKFIENFRHIEIQILGDEHGNVIH
                     LGERDCTIQRRMQKLVEESPSPILTEEKRKEMGDAAVRAAKAVNYFNAGTIEFIYDLDE
                     DQFYFMEMNTRIQVEHPVTEMVTGVDLVKQQIKVAMGEKLPYTQDDIQIQGHAIEFRIN
                     AENPYKNFMPSPGKVEQYLTPGGFGVRIDSACYTNYVIPPYYDSMVAKLIVHQPTREEA
                     IMSGLRALSEFVVLGIDTTIPFHIRLLNHPVFNQGFFSTKFLEIYDIMNEDH"
     gene            7670..8044
                     /locus_tag="JGZ50_RS06050"
                     /old_locus_tag="JGZ50_06050"
     CDS             7670..8044
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613838.1"
                     /locus_tag="JGZ50_RS06050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06050"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_014613838.1"
                     /transl_table=11
                     /translation="MAKPIEHFNPNLGSVEIEPEVISVIASIAVSEVKGVEGVFPDLKN
                     STLERFGRKNLSKGVKITTKDNEITIDVYCSLNYGVKVSETALKVQESIHSALRTMTAL
                     TPQQINVHITHIEMAKNNRD"
     gene            8065..8457
                     /gene="nusB"
                     /locus_tag="JGZ50_RS06055"
                     /old_locus_tag="JGZ50_06055"
     CDS             8065..8457
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016425154.1"
                     /locus_tag="JGZ50_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06055"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_014613839.1"
                     /transl_table=11
                     /translation="MSRKQARSQAFQTLFQLEMKNTELTIDEAISFIKEDYPDLDFDFI
                     KWLVSGVKDHQHVLDETISPHLNGWTIARLLKTDRIILRMATFEMNHSDTPEKVIINEA
                     VELAKQFSDDDHYKFINGVLSHIKRN"
     gene            8466..9812
                     /gene="xseA"
                     /locus_tag="JGZ50_RS06060"
                     /old_locus_tag="JGZ50_06060"
     CDS             8466..9812
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019165246.1"
                     /locus_tag="JGZ50_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06060"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_014613840.1"
                     /transl_table=11
                     /translation="MEKYLTISALTKYIKYKFDQDPHLQSVYIKGELSNFKRHSSGHLY
                     FAVKDENSVIAAMMFKTQANQLDFDPKEGDQVLIEARVSVYERRGNYQIYVNHMQLDGV
                     GNLYQKFEQLKNKLMKEGYFDPAHKKPIPKYPQKIAILTASTGAAIRDIQNTLNNRYPL
                     AQQIKISTLVQGAQAKADIIEKLQSADQLGADVIILGRGGGSIEDLWNFNEEDVVKAIF
                     SCQTPVISAVGHETDTTLSDFVADLRAATPTQAAMLATPDKQELKQVLYQTRAYLNRYM
                     KQHLKHTSQQLQQLQSYYKLKQPGLLYEQQIQKRDELDRALHQSMQLRLQHEQQRLAML
                     QQRIRIKYFYDNVQRQKQASIDLSSQLHKQIQRILTSKKQIFQHQLLSLDNLSPTKTML
                     RGYSIVKKDDEVITSSHDIHEGERIEVTMKDGALDARIEKVRWQNDDRK"
     gene            9796..10020
                     /locus_tag="JGZ50_RS06065"
                     /old_locus_tag="JGZ50_06065"
     CDS             9796..10020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613841.1"
                     /locus_tag="JGZ50_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06065"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_014613841.1"
                     /transl_table=11
                     /translation="MTTENKSFEEMMKELENIVNQLDHDTISLEKSLELYQQGIALSKS
                     CEKTLSDAEKKVAELMDKEADESNESKSE"
     gene            10001..10882
                     /locus_tag="JGZ50_RS06070"
                     /old_locus_tag="JGZ50_06070"
     CDS             10001..10882
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729158.1"
                     /locus_tag="JGZ50_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06070"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_041613228.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-59, bitscore:
                     198.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQNLNELLEQFNGHLNHAIEDSQLGTSLEQSMRYSLEAGGKRIR
                     PLLMLATIKMLDHQKLESGMHVALALEMIHTYSLIHDDLPAMDDDDLRRGKPTNHTVYG
                     EWLAILAGDALLTKAFEKIALTPHIDAQIKVALIEKISQASGHQGMVGGQTLDMQSENQ
                     QISLEKLESIHIHKTGALIQFAIEAATIITSIRQTTAQQLIQFSQHLGVIFQIKDDLLD
                     VYGNEAKLGKPVGSDVTNHKSTYVTLLGEKGAEQELQAHIQKAEAILTSLSTEFDTTDL
                     NYLLTLFYQRQN"
     gene            10952..12820
                     /gene="dxs"
                     /locus_tag="JGZ50_RS06075"
                     /old_locus_tag="JGZ50_06075"
     CDS             10952..12820
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219621.1"
                     /locus_tag="JGZ50_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06075"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_070407418.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 4.2e-115,
                     bitscore: 380.8, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVRNIQNPSFLKSLSVKELEALSHDVRQFLIQTCAVTGGHIGAN
                     LGVVELTIALHKHFNSPEDKIIWDVGHQSYIHKILTGRGHQFETLRQYRGLCGFPKLKE
                     SDHDVWEAGHSSTSLSAAMGMAKARDILGKKNHIVPVIGDGALTGGMALEALNNIGHDR
                     TNMTIILNDNEMSIAPNVGAMHNMLGRIRMNQGYNRLKFDAESILSRLPGGSRLRESAD
                     RIKDSLKYLVVDGAFFEELGIRYIGPVDGHSFEELEIALAAADSINKPVLIHVVTKKGK
                     GYHPAENDKIGTWHGLGPYKLETGEQIKGQTQGPSWSQLMSDEILSYAKKDRRVVAITP
                     AMPVGSKLTKFQSELPEQFFDVGIAEQHAVTMAAGLAIEGMKPYVAIYSTFLQRAYDQV
                     LHDVDRQNLNVIFGVDRSGLVGADGETHQGVFDVGFLTQFPNMIVTMPKDENEAKNLVY
                     TAMHHAQGPIAIRYPRGNGLGVEITDKREHLPIGTWEDLTEGQDVALISYGPTLATLVE
                     VAKTLAEQGIRARVINARYIKPMDTTVLGDLGAKNTPVVTVEEAMLNGGLGSQIANYFT
                     DHGYTNRIKRLGIDDTYIEHGDVEQILEDLGLTHDPLVHTIQQFLD"
     gene            13105..13557
                     /gene="argR"
                     /locus_tag="JGZ50_RS06080"
                     /old_locus_tag="JGZ50_06080"
     CDS             13105..13557
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500131.1"
                     /locus_tag="JGZ50_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06080"
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_014613844.1"
                     /transl_table=11
                     /translation="MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDMNVTQATVSRD
                     IKELQLIKVPAPSGQYIYSLPNDRRYHPLEKLGRYLMDSFVKIDSANNLLVLKTLPGNA
                     QSIGAILDQIDWEEVLGTICGDDTCLIICRDNPSADEIKERIFNML"
     gene            13571..15253
                     /gene="recN"
                     /locus_tag="JGZ50_RS06085"
                     /old_locus_tag="JGZ50_06085"
     CDS             13571..15253
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729156.1"
                     /locus_tag="JGZ50_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06085"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_199274943.1"
                     /transl_table=11
                     /translation="MLQSLSIKQFAIIDTLDIQFSDGLTVLSGETGAGKSIIIDAIGQL
                     IGMRASSEFVRHGEKKAIIEGIFDIDDATDAIRQLETLGIDINEDFLIVKREIFSSGKS
                     ICRINNQTVTLQDLRQVMQSLLDIHGQHETQSLLKQKYHVELLDRYADGEYIKELQQYA
                     QSYEQHQEKIKELEALESADQALLQRLDLMKFQYDELKEAQLKEGEIEQLEIDIKRIQN
                     SENLSLALNAAYVTLTDEHAITDRLYTLSSELQNVNQILPETFEKLKEEVDQFYYTLED
                     AKHQIYEEINQTEFDEQYLNELESRMNLLNNLKRKYGKDISDLMIYQEKIADEINKIEN
                     YEESTSKLREEIQQLSQQVQEDGEKLAKARRIVARQLRDRIVNEIQYLQMKDANLEISF
                     KPYETPQKDGLERIEFLISPNKGEPLKSLNKIASGGELSRIMLALKSIFVRAHGQTAIL
                     FDEVDSGVSGQAAQKMAEKMKDIASVIQVICISHLPQVASMSDHHLYISKHEKDDRTTT
                     TVRELTGDARIDEIARMISGATVTELTRENAKEMIEQNQKHKG"
     gene            15260..16153
                     /locus_tag="JGZ50_RS06090"
                     /old_locus_tag="JGZ50_06090"
     CDS             15260..16153
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613846.1"
                     /locus_tag="JGZ50_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06090"
                     /product="phosphate acyltransferase"
                     /protein_id="WP_096535707.1"
                     /transl_table=11
                     /translation="MNFTDLLKEPQALTGTIAIVNATDEPLIRVIIEVLKQTEADFKLY
                     NNQDVAEIIRSFDLSADFLKRIHIQTFDTEEAAIEGCLNDLYHGKAQILMKGQISTAKI
                     LSAVLKRNAQGTKPFLNHVALCEIPSYHKLLMISDVALNIAPTEEEMKAIIQNLVDFSK
                     RLQYQQLHIALLSSVEKVSPKIPSTVQAERLSEYYQSHPIEPHVHVEGPFALDNAIDKK
                     SAIQKGIHSKVAGNADVLIVPGLDAGNVLYKSLTYFGRAKVASLILGAHFPIVLTSRAD
                     SIENKINSILVALKVG"
     misc_feature    complement(16371..16382)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            16727..17785
                     /gene="buk"
                     /locus_tag="JGZ50_RS06095"
                     /old_locus_tag="JGZ50_06095"
     CDS             16727..17785
                     /EC_number="2.7.2.7"
                     /GO_function="GO:0047761 - butyrate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /gene="buk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613847.1"
                     /locus_tag="JGZ50_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06095"
                     /product="butyrate kinase"
                     /protein_id="WP_063278764.1"
                     /transl_table=11
                     /translation="MTTTLVLNLGSTSSKYAIYENDECKVNENISHTEAILKQPLIDQE
                     SLRQQLIEDEIESQGYQLNQIDAIACRGGLLKPLEGGTYSVNEAMYDDLKSFKYGAHAS
                     NLSAMIGYQLGQKYHIPVFTTDPVVVDELIDEVRHTGVPSIQRRSIFHALNQKAMARRY
                     AALVNRAYENMNVIVIHMGGGISIGAHEKGRVIDVNEALYGEGPMAMDRSGSIPNDLLV
                     QYMEKHQLSADEIKVQLSRESGLKAYFQTSDLREIMAKYEQDENVKLIIDTMVIQIAKV
                     IGERAVVLKGHVDQIIFTGGMSHSVQLMDQLAKYIEWIAPISVFPGEHELITLAERAQL
                     ALNQQIKIEIYQ"
     gene            17796..19214
                     /gene="lpdA"
                     /locus_tag="JGZ50_RS06100"
                     /old_locus_tag="JGZ50_06100"
     CDS             17796..19214
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001662867.1"
                     /locus_tag="JGZ50_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06100"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_063278763.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-61, bitscore:
                     205.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEKYDIVILGGGIAGYSAAIRASQLGKSVAIVEKSKMGGTCLH
                     QGCIPTKSFLKSAEVFQYVQHADDFGVTAEPPTFNFSKVMERKNRIVDTMYQGLQGLMK
                     RHKIDVFHGVGRLMGASIFTPQSGTVSVEYEDGTSELLPNDYVLIATGSKPMALPFLPF
                     DQQQIYSSNDMMTLEALPQSITIIGGGVIGLEFASFFSSVGVTVHIIEAGPRILPTENA
                     QISQLIQKQLEEQGVNFHINTVLKGDDIQQSDEEVTFNLEKPFSTEKVLVAIGRQVNTA
                     DLGLDNTKVVLNDKQMIETNEYMQTADTHIYAAGDVIGHLQLAHVGAREGVIAVEHMFN
                     ENPLPVDYDLMPRCVYTSPEIASIGVNQETAKQRGLKFEVMKAPFKANGKATITTSSTS
                     EGFAELLFDQASGSLIGASLIGPHVTELINELSVLQFMNGSALELGLSTHAHPSISELL
                     MELGLKSNHQSIHI"
     gene            19236..20234
                     /locus_tag="JGZ50_RS06105"
                     /old_locus_tag="JGZ50_06105"
     CDS             19236..20234
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613849.1"
                     /locus_tag="JGZ50_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JGZ50_06105"
                     /product="thiamine pyrophosphate-dependent dehydrogenase E1
                     component subunit alpha"
                     /protein_id="WP_014613849.1"
                     /transl_table=11
                     /translation="MKDYQSVGLEIEDLKNMYRAMDLGRKLDERMWLLNRAGKIPFVIS
                     CQGQEATQIGTAYALQKGDITSPYYRDLALVTYLGMTPLETMLSAFGKRDDISSGGKQM
                     PSHFSKKEVGIMSQGSSVATQILHAVGAALTFKMDGKSQIALTTLGEGSSNQGDFHEGL
                     NFAGVHNLPFICLIENNKYAISVSKEFQYGAKYLSDRAKGYGMFGETIDGNDPIAVYGA
                     IKKARERAVNGEGASLIEAMCTRLTAHSSDDDDRYRTVEEKNADKENDCNLKFKQYLID
                     QSLVDETWFESIEKENQQWVHQATKEAEAAPYPDPSETYLHVYEEGGRQHG"
ORIGIN
        1 ttcactccaa cctgcagcgg gcgcacatgg tgaatggaca gcactgatga ttttcaaggc
       61 atatcaccta caaaatggcg atgcagaaag agatgaagtc attgtacctg actcagcgca
      121 tggtacgaat ccagcttctg cagcgtttgc tggtttcaaa tctgtcacag ttaagtcgaa
      181 tgaaaaaggt gaagtagata tcgcccacct aaaagaagtc gtgagtgata aaacagctgc
      241 aattatgtta acaaacccga atacattagg tatttttgaa acgaatatta tggaaatccg
      301 cgatattgtg catgaagcag ggggcttact atactacgat ggcgctaacc tcaatgcaat
      361 tatggataaa gtacgtccag gagacatggg atttgatgct gttcacctta atttacacaa
      421 aacatttaca gggcctcatg gcggtggtgg tccaggttca ggtccaatcg gcgtgaaaaa
      481 agagttgcgt gattacttac cgaaaccact cgttgtgaaa aatggcgacc gttttgagta
      541 tgataatgac atcccatatt ccattggacg tgtgaaacca ttctacggca acttcggtat
      601 ttatttacgt gcttatacgt atattcgtac aatgggttat caaggattga aagaagtgtc
      661 tgaagcggct gtgttaaatg cgaactacat gaaagcgcgt ttaaaagata cgttcgttat
      721 tccatttgat caatattgta aacatgaatt tgtattaagt ggtacgaagc aaaagaaact
      781 gggtgtacgt actttagata tggcgaaacg tttattagac tttggcgttc atccacctac
      841 agtttatttc ccactcattg ttgatgaagg tatgatgatc gaaccgacag aaacagaatc
      901 taaagaaacg ctagactatt tttgtgatgc cttaatccaa attgcgaaag aagctgagga
      961 agatccagat aaagtgttag aagcaccaca tacaacaatt atcgatcgtt tggatgaaac
     1021 tacagcagca cgtaagccaa ttttaaaatt tgagaactta aaagaagaaa agtaactaga
     1081 ttttacgacc tgtttattgt ttctaatcat aaacagaggg atgggacata aaaatttttg
     1141 atgcccaccc ctgtttttat ttgaacgtga tatttattgt gtgattcagc gtaaaatgct
     1201 aaaatatagg aattgcgaac atttgttcta aaccttaaaa aacgtggcat catggctatt
     1261 ctttcttttt aagcgtagta ttgtctactt ttatcttttc gatctatcca tgctttttca
     1321 aaaatttata aatgtgatag aaagtcaaca tactacgatt ctgatttaat caaacacata
     1381 aaaaagagct agattatcca catttttact ggatccacta gctcttttta ctatttttta
     1441 gatttaatct tgcccgtcca ttttttgtag ccgcctttta acatgtacaa gttcgtatat
     1501 ccttttttct taagtgtacg tgcagctcga taacttgcga taccatttgc atcaacaaga
     1561 tagatgggtt gatcttttct taatccttgg tatcgttgac gaaacattgt catagggata
     1621 tttcgtgcac caataatatg accataatca tagtctgcct tttctctaag atcgatcact
     1681 tgtgcttttc taataccttc ttgaaattct tcttggttta attctgttac tgatcgctta
     1741 ttaatgataa agttcgttac catccaaatg atgaccaatg ctaacacaat taaaacgatt
     1801 aatgtcatgt tactcatctt gcatcctccc taaaataccg atattattat tataagactg
     1861 atagactaat ttatcaaaat ttttatgtgt gacatatgtt ggcaatttta aattttttga
     1921 aacataacat atgcccgatg agatttcata gggaggcttt atagcaaatg acagaaactt
     1981 ggcattttat gaatacagga agtcatcatc catactacaa tatggcattg gatgaggctt
     2041 tgttaaattt tgtatcaaga ggagaaattg atccggtcgt tcgattctac acttggaatc
     2101 caccaacgtt atcaattggt tatttccaac gactctccaa agaaattgac atcgaaaagg
     2161 tcaaagaaaa gggctacggt ttagtgagac gccaaacagg aggccgtggt gttttacatg
     2221 ataaagaatt aacttatagt gtgatcgtac cagaagctca tcctgatatg cctcaaaccg
     2281 ttactgaagc ctatcgtgtg atttcaggtg gtttactaga aggctttaaa tcattaggct
     2341 ttgatgcaca tttcgcggta ccacgttcaa aagaagagcg agagaagctc aaacaaccga
     2401 gaagttctgt ttgttttgat gcaccaagtt ggtatgaact cgttgttgaa ggtaaaaaaa
     2461 tcgctggcag tgctcaaacg agacaaaagg gcgtgatttt acagcacggt tcgattcttc
     2521 aagatgtgga tattgatgac ttgttcgaca tgtttatttt caaaaacgag agattgaaag
     2581 caaaaatgaa agaagccttt gtcgaaaaag cagtggccat taatgattta tcaaatgaaa
     2641 caatcacttt agcacaaatg gaagtggcgt ttaaagaagg tttcaaaaaa gcactcgata
     2701 ttgaatttaa accgctagaa ttaacagtag cgcaacaaga tgaagtaaaa gcattagaag
     2761 aaaaatatcg ttcagaggca tttttatatc gcaaataatc atcaggttta atcactgtaa
     2821 attaaaaggc tggaaaacgc tcaatgatat gcgcccagcc ttataatatt gttaacttca
     2881 atttttctca ataagtgatt cttaaacacg cacttatcga cgtcctttga atttattttt
     2941 ccaaacacgc tttttgtaat cccgttgatc tggcgttaaa aagaaaaaga aatagactaa
     3001 atagatgatg ccgacaataa tagctactgt aatgattgat ctaaaaatac taaaaagtac
     3061 tacatctaaa ttgaaaatta atccgattag tgcgacaaaa attattacac cgaatatcat
     3121 tttttggaaa gttgtcatgt taattactcc tctttatatt atcctgcatt tgtagttttc
     3181 acattgatgt ttgataagct ctgacgtcct ttttgaattt catttttatc tttcgcttta
     3241 taaccttttc gaatcattgt taaagcactg ttgatttctt tttgtagttt tctaatttct
     3301 ttgtcctgtg ctttgattga tttatccttt ttaacaatct tttcatcttc cgtggcatct
     3361 tggtaacttt ccatcgcact ttcatgatcc tcaataattt gatctaattg atccaacact
     3421 ttatcctctt ttttgtttgc taacactttc gaatcaattt gttggtaggc attaatcgca
     3481 tccgttacag aggcataata ttgtgatgaa atttcaagat aatctgcttt tttctgatta
     3541 gacttcgctt gttttgtatt ctctgagtct tttttcaaag cgtccacttg tttttgtttt
     3601 ttcgcatttt catttttaag ttgctgattt tctaatttaa tttcatgatt tttgtcactt
     3661 aaatccgtac ttctcttttc tagaggtaac aggttttgac ttccacaggc tgacaataaa
     3721 aatgcaacac tgatactcgc acaaattctc tttttcatat taaactccta aacactcaat
     3781 tgtttttcac tacatatgac tacattttaa ggtatcatgt aattaagtac aaatataagg
     3841 aggaattttt gtatgaaaaa tagacttcaa aagataagaa ctttattaca agacaaacat
     3901 ctcgatggtt taactgtgtt atctgacttt aatcgccgct atttatcagg gtttacaggt
     3961 acaagtggcg cactcatcat tacacaggac aaagcactac tcattacaga tttccgatat
     4021 actgatcaag cacaacagca agccactgag tttgaggtca ttttacaaaa aggtgatttg
     4081 ttctccgcat taacagaaca atttaaaaca ttaaatttac aaaatattgg ttttgaaggt
     4141 catctcgtcg cttatgattc atttttaaaa ttaaaccaag gccgtcacga tctcatttct
     4201 atcggtcaag ctattgaaac gattcgtcaa acgaaagatg aaggtgaaat taaagcgatt
     4261 caaaaagcag cacaaattgt ggatgaagca tataaatata ttctcactgt cgttaaaccg
     4321 ggtatgactg aaaaagaagt taaggcgcat ttggaaagta aaatgttgca tttaggcgca
     4381 gacgacacgt catttgatac tatcgtcgct tcaggtattc gaggtgcgat gccacacggt
     4441 gtagcttccg ataaagtcat tcagtcagga gaaatggtca cgttagactt tggtgcttac
     4501 tacaacggtt attgttcaga tatcacacgt actttcgctg tcggccaacc ttctgaagaa
     4561 atggttaaaa tttacaatat cgtgttgaaa agtcaagaag ccgccattgc agcgattcgt
     4621 ccaggaatga caggtaaaga aatggatagt attgcgcgag atattattac agaagcgggt
     4681 tacggaaaac actttggtca ttcgttaggt cacggtatcg gtttagacat tcatgaactt
     4741 cctggcctgt ctcaaaaatc agatgtcgtc ttagaaaaaa atcattgtgt gacgattgaa
     4801 cctggtattt acgtagaagg attaggtggt gttcgtatag aagatgatat tttaattaca
     4861 gaaaatggcg gcgaacgctt tactaattgc acaaaagacc ttattatttt aaaagaagag
     4921 tgattctgag gaggaaactg aatgatttct gtaaatgatt ttaaaacagg cttaacgatt
     4981 tctgttgata acggaatctg gaaagtaata gaattccaac atgttaaacc tggtaaagga
     5041 tctgcgtttg taagatcaaa attacgtaat ttaagaacag gtgcaatcca agaaaaaact
     5101 ttccgtgcag gcgaaaaagt tgagcccgcg atgattgaaa accgccgtat gcaatatttg
     5161 tatgctgatg gcgacaatca cgtattcatg gacaacgaaa ctttcgaaca aacagaacta
     5221 agcacagatt acttagaata cgaattgaag tttttaaaag caaacatgga tgtacatatc
     5281 caaacgtacc aaggcgaaac aatcggtgtg gaattaccaa aaactgttga acttgaagta
     5341 actgaaactg aacctgggat taaaggggat acagcgacag gggcaacaaa atcagcaacg
     5401 gttgaaacag gttacacatt gaatgtgccg ttattcgtta atgaaggcga tgtgttagtc
     5461 attaacacaa cagatggtag ctacgtatca cgtggttaat ttaattcata tcaggtgaac
     5521 gagattttcc tgataatgtg accaatagaa tattattatt ggactaatga ggctgatgat
     5581 tgtcttgtta gtccatattt tatttttaag ctatacatag ccataatcag cgttgtttat
     5641 tctatctatt aacatagcat cgttgaatat ttcaaagacg atacgatcaa ccaaagcgaa
     5701 tcgattgaat catttagtaa gaatgaaaaa gtcactacta cgctttagat attatgtatt
     5761 ttcttgaatt gccttataca ctcaagtaaa atagtagggt agaaataatc aatcataagg
     5821 gagtaaccaa aatgaatttt aaagagatta aagaattaat taatattcta gacaattcta
     5881 acctcactga aatcagtatt gaagataaag gtacaacgat caacttaaaa aagaaaaaga
     5941 aattgtaact caacaaatct cagcacctca gcaaatggtt gcaccaactg taacagctga
     6001 acctgtccaa gtaaacgctg catcagtaga tacaccaaca acagaggctg atgcatcact
     6061 caaaacgatt acagcaccta tggtcggtac attctataaa tcaccgtctc ctgaagagag
     6121 cgcttatgtt caaatcggtg atcaagtgac acctgataca actgtttgta tattagaagc
     6181 catgaagtta tttaatgaaa ttcaagctga agtggctggt gaaatcgttg aaattttagt
     6241 tgaagatgga caaatggttg agtatggcca agctttattc aaggtgaaat aatatgagaa
     6301 aaatattaat tgcaaaccgt ggcgagattg cagtgcgcat tattcgcgca tgtcacgaat
     6361 tgggtatcca aactgtagcg atttattctg aaggcgacaa agatgcatta catactcaat
     6421 tagccgacga agcctactgt gtggggccca agcaatcaaa ggattcgtac ttgaacatac
     6481 cgaacatttt atctatcgcc acttctacgg gatgtgacgg tattcaccct ggctatggct
     6541 tcttggctga aaatggtgat tttgcggaat tgtgtgaagc tgtccaactg aagtttattg
     6601 gaccgagcta tgaatcgatt cagaaaatgg ggattaaaga tattgcaaaa gaagaaatga
     6661 aacgtgcaaa tgtccctgtt gttcctggta gtgagggact tgtgaacacg attgaagatg
     6721 ccatccaaac tgctaactca attggttacc ctgttattat aaaagcaact gctggtggtg
     6781 gtggtaaagg gattcgtatc gcacgaaatg aagaagaatt aatcaatggt tataaaatga
     6841 cacaacaaga agcagaaaca gctttcggta atggtggctt atatttagag aaatttattg
     6901 aaaacttccg tcatattgaa attcaaattc ttggtgatga gcatggaaac gtgattcacc
     6961 ttggcgaacg tgattgtacg attcaacgcc gcatgcaaaa gcttgttgaa gaatcaccct
     7021 ctccaattct tactgaagag aaaagaaaag agatgggtga tgcagctgta agagcagcta
     7081 aagcggtcaa ttattttaac gcaggaacta ttgaatttat atatgattta gatgaagatc
     7141 aattttactt tatggaaatg aatacgcgaa ttcaagtcga gcatccagtg actgaaatgg
     7201 tgacaggtgt ggatctcgta aaacaacaaa tcaaagtggc tatgggagaa aaattacctt
     7261 atacacagga tgatattcaa attcaaggtc atgccattga atttcgtatc aacgctgaaa
     7321 atccttataa aaactttatg ccttcacctg gtaaagtcga acagtattta acaccaggcg
     7381 gatttggtgt acggattgat tcagcttgtt acacgaacta tgtcattcca ccatactatg
     7441 attcaatggt tgcgaaattg attgtacatc aaccgacgag agaggaagcc attatgtctg
     7501 gtttacgtgc gctcagtgaa tttgtcgtac tcggaatcga tacaaccatt cctttccata
     7561 ttcgtttact aaatcatcca gtcttcaatc aaggtttctt tagcaccaaa tttttagaga
     7621 tttacgatat tatgaatgaa gatcattaaa ttgaatgggg gcaacttata tggcaaagcc
     7681 aattgaacat ttcaacccaa atcttggaag tgttgaaatc gaacctgaag tcatttctgt
     7741 tattgcaagt attgcagtgt cagaagtgaa gggtgttgaa ggggtatttc cggatttaaa
     7801 aaattcaact ttggaacgct ttggtcgcaa aaacttaagt aagggcgtta aaatcacaac
     7861 aaaagacaat gaaatcacta ttgatgtcta ttgttcttta aattatggcg ttaaagtttc
     7921 cgaaacagcg ttaaaagttc aagaatccat tcatagtgca ttgcgaacga tgactgcact
     7981 cacacctcaa caaatcaatg tgcacattac acatatagaa atggccaaaa ataatcgtga
     8041 ttaactgatg aacggagaat taaaatgagt agaaaacaag caagaagtca agcctttcaa
     8101 acattattcc aactagagat gaaaaataca gagttgacga ttgatgaagc gattagtttt
     8161 ataaaagaag actatccaga tttagatttc gacttcatta aatggcttgt ttctggtgtg
     8221 aaagatcatc aacatgtttt agacgaaaca attagtccgc atttgaacgg atggacgatt
     8281 gcgcgtttgt tgaaaactga tcgtatcatt ttgcgtatgg cgacatttga aatgaaccac
     8341 agtgatacac cagaaaaagt tattattaat gaagcagtag aactggcaaa acaatttagc
     8401 gatgatgatc attataaatt tatcaatggt gtattaagtc acattaaaag aaattgagtg
     8461 atggcatgga aaaatattta acaatctctg cattaactaa atatattaaa tataaatttg
     8521 atcaagaccc acatcttcaa agtgtctaca tcaagggtga attgtcgaat tttaagcgtc
     8581 acagtagtgg tcatttatat tttgccgtta aagatgaaaa cagtgttatc gctgcaatga
     8641 tgtttaaaac acaggcaaat caacttgatt tcgacccaaa agaaggagat caagttctca
     8701 ttgaagcacg agtatcagtt tatgaacgac gtggtaacta tcagatttac gttaatcata
     8761 tgcaactgga cggggtaggg aatctttacc aaaaatttga gcaattaaaa aataagctta
     8821 tgaaagaagg gtattttgac cctgctcata aaaaacctat acctaagtat cctcaaaaaa
     8881 ttgcgatact tacagccagt accggcgcag ctattcgaga tattcaaaac actttgaaca
     8941 atcgttaccc acttgctcaa caaatcaaaa tcagtacact cgtacaaggg gcacaagcaa
     9001 aagcggacat catcgaaaaa ttacaatctg cggatcaact cggtgcagat gtgattatac
     9061 ttggacgggg tggcggctca attgaagatt tgtggaactt caatgaggaa gatgttgtta
     9121 aagctatttt ttcatgtcaa acacctgtta tatctgctgt tggacatgaa acagatacaa
     9181 cacttagtga ctttgttgct gatttacgtg ccgcgacacc gacacaagct gcgatgttag
     9241 cgacgccgga caaacaagag ctcaaacaag tgttgtatca aacgcgtgcg tatttaaatc
     9301 gttatatgaa gcaacattta aaacacacat cacaacaact acagcagctg caatcgtatt
     9361 acaaacttaa gcaacctggt ttgttatatg aacagcaaat acaaaaacgt gacgagctcg
     9421 atcgcgccct tcatcaatct atgcaattgc gactacaaca tgaacaacaa cggttagcga
     9481 tgttgcaaca acgcattcgc attaaatatt tttatgataa cgtacaacgt caaaagcaag
     9541 catctataga tttatcatct cagttacata aacaaattca acgtatttta acttctaaaa
     9601 agcaaatctt tcaacatcaa ctgttatcgc ttgataattt gagtcctaca aagacgatgt
     9661 tacgaggcta ctctatagtt aaaaaagatg atgaagttat tacgagtagt catgacatac
     9721 atgaaggtga acgcattgaa gtcactatga aagatggcgc tttagatgca agaattgaaa
     9781 aggtgaggtg gcaaaatgac gaccgaaaat aaatcttttg aagaaatgat gaaagaatta
     9841 gagaatattg taaatcagct agatcatgat acgatatcgc tagaaaaatc tttagaattg
     9901 tatcaacaag gcattgcgct ttctaaatca tgtgaaaaaa cattgagtga tgctgagaag
     9961 aaagtagcag aattaatgga taaagaggca gatgaaagta atgaatcaaa atctgaatga
    10021 gttattagaa caatttaatg gccacttgaa tcatgcaatt gaagattctc aactaggtac
    10081 ttctcttgaa cagagtatgc gttattctct agaagctggt gggaaaagaa tacgcccctt
    10141 actcatgcta gctacaatta aaatgttgga tcatcaaaag cttgagagtg gtatgcatgt
    10201 tgctttagcg ctcgaaatga ttcatacata ttcattgatt catgatgatt tacccgcaat
    10261 ggatgatgat gatttgcgac gtggtaaacc gacgaatcat acggtctatg gtgagtggct
    10321 agcgatattg gctggagacg ccttgttgac aaaagcgttc gaaaagattg cgttgacacc
    10381 tcatatcgac gctcaaatta aagttgcact tattgaaaaa ataagtcaag caagtggaca
    10441 tcaaggtatg gtaggcggtc aaacattaga catgcaaagt gaaaatcaac aaatttcact
    10501 cgaaaaactc gaaagcattc acattcataa gacgggtgca ctgattcagt ttgcgattga
    10561 agctgcaaca atcattacat caattcgtca aacaactgca caacaattga ttcagttctc
    10621 tcaacattta ggtgtcattt tccaaattaa agatgacctc ttagatgtgt atggtaatga
    10681 agcgaaatta ggcaaaccag ttggaagtga tgtcactaat cataaaagta cgtatgtcac
    10741 acttttaggt gagaagggtg ctgaacaaga acttcaagca catattcaaa aagccgaagc
    10801 cattttaaca tcattatcaa cggaatttga tacaacagat ttaaactatt tgttaacact
    10861 tttttaccaa cgtcaaaatt aggttctgtc tatctatgat gtgattgaag tgttataatc
    10921 agtacgaaag aaaaaattaa gggtgatttc aatggacgta agaaatatac agaatccttc
    10981 attcttaaaa agtctttctg ttaaagagct tgaagcattg agtcacgatg tgagacagtt
    11041 cttaattcaa acgtgtgctg tcacgggggg ccatattggt gcaaatttag gtgttgttga
    11101 actcacaatc gcactgcata agcattttaa tagtccagaa gataaaatta tctgggatgt
    11161 cggtcatcaa agttacattc ataaaatttt gacaggccgc ggtcatcagt ttgaaacatt
    11221 aagacaatat agaggattat gtggatttcc aaaattaaaa gagtctgatc atgatgtgtg
    11281 ggaagctggg catagttcta cctcattatc agcagcgatg ggcatggcaa aagcgagaga
    11341 tattttaggc aaaaagaatc atatcgttcc agttattggt gatggtgcac tgactggtgg
    11401 tatggcactt gaagctttaa acaacatcgg ccatgaccgt acaaacatga caattatttt
    11461 aaacgataac gaaatgagta tcgcacctaa tgttggcgcg atgcataaca tgctcggtcg
    11521 tattcgaatg aaccaaggtt ataaccgact caaatttgat gctgaatcga ttttaagtcg
    11581 tttgcctggg ggcagtcgat tacgtgaatc tgctgatcgt atcaaagaca gcttaaaata
    11641 tttagttgta gatggcgcgt ttttcgaaga gctcggaatt cgttatattg gtccagttga
    11701 tggccatagc tttgaagaac tggagattgc cttggctgca gcagattcta ttaacaaacc
    11761 agtgttgatt catgttgtaa cgaaaaaagg gaaaggttac catccagctg aaaatgataa
    11821 aattggcact tggcacggct taggaccata caaattagaa actggcgaac agattaaagg
    11881 ccaaacacaa ggaccttcat ggagtcagtt aatgagtgat gaaattctgt catatgcgaa
    11941 aaaggatcgt cgtgtcgttg ctattacacc tgcaatgcct gtaggttcta aacttacaaa
    12001 attccagtcc gagttgccgg aacaattttt tgacgtcggt attgctgaac aacatgctgt
    12061 cacgatggcg gctggtttag cgatagaagg tatgaaaccg tatgttgcga tctattcaac
    12121 atttttacaa cgcgcgtatg accaagtgtt acatgatgtc gatcgtcaaa acttaaacgt
    12181 catttttgga gtggatcgct ctggccttgt cggtgcagac ggtgaaacgc atcaaggtgt
    12241 gtttgatgtt ggtttcttga cacaatttcc aaatatgatt gtaacgatgc ctaaagatga
    12301 aaatgaagcg aaaaatctcg tttatacagc gatgcatcat gcacaagggc caattgcaat
    12361 tcgttatcca cgtggcaatg gtttaggcgt tgaaatcact gataaacgtg agcacttgcc
    12421 tattggaaca tgggaagact taactgaagg tcaagacgtg gctcttatca gctatggacc
    12481 cacactcgcg actttagttg aagttgctaa aactttagca gagcaaggga ttcgagcacg
    12541 cgtcattaat gcacgttata tcaaaccgat ggacacgact gtcttaggtg acttaggtgc
    12601 caaaaacacg cctgtggtta cagttgagga agcgatgcta aatggtggct taggcagtca
    12661 aatcgcaaat tacttcaccg atcatggata caccaatcgt atcaaaagac tcggtattga
    12721 tgatacgtac attgagcacg gagatgtaga gcaaatttta gaagatttag ggttaacgca
    12781 tgacccgctc gttcatacaa ttcaacaatt tttagactaa catccaaaca cgagtaatgt
    12841 attacagttg ctcgtgtttt tttaatggat ggaaatgacc acatttgttt catttcaatt
    12901 ctatctttat tcaattttcc tactcaaaag gagaatcata tacatttttc gtatatattg
    12961 aatcgttacg cacgctgttt ttgaatttta aaagtcaatc gttatatcaa ttgtttctta
    13021 cgatgacgta catcacttaa gtaggtaaat cataaccgag tgtggtaaaa tcattgtata
    13081 aatattcgtt acgaggtgtc tattatgcct aaaaaatctg taagacatat aaaaattaga
    13141 gaaattattt caaacgaaca aatcgagaca caagacgagt tggtgaaacg tttaaatgat
    13201 tacgatatga acgtcacgca agcaacagtg tcacgagata ttaaagagct tcaattaatt
    13261 aaagtccctg caccaagtgg tcaatatatt tatagtttgc ctaatgatcg tcgttatcat
    13321 ccacttgaaa aactaggacg ttatttgatg gattcatttg taaaaatcga cagtgctaat
    13381 aatttactcg tgctaaaaac gttgccaggt aatgcacaat caattggtgc gatactggat
    13441 caaattgatt gggaagaagt gctaggtacg atttgtggtg atgatacgtg cttaattatt
    13501 tgtcgcgata acccttcagc tgatgaaatt aaagaaagaa ttttcaatat gttataagga
    13561 tggatgtcag atgttacaaa gcctctccat taaacaattt gctattatcg atacattaga
    13621 tattcagttt tcagatggcc tcactgtgct tagtggtgaa actggtgcgg gtaaatcaat
    13681 cattattgat gccattggac aactgattgg tatgcgtgct tcctctgaat ttgtacgaca
    13741 tggtgaaaag aaagcaatta ttgaaggcat ttttgatatt gatgatgcga cagatgcgat
    13801 acgtcaactt gaaacgttag gaattgatat taatgaagac tttttaattg ttaaacgaga
    13861 aatttttagt tctggtaaaa gtatctgtag aattaacaac caaactgtga cgttacaaga
    13921 tttaagacaa gtcatgcaat ctttacttga catccatggt caacatgaaa cacaatcttt
    13981 attaaaacaa aagtatcacg ttgaactact tgatcgttat gctgacggtg aatatattaa
    14041 agaacttcag caatatgccc aatcttatga acaacatcaa gaaaagataa aagagcttga
    14101 agcactagag tctgcagatc aagctttatt acaacgccta gatttaatga agttccaata
    14161 tgatgaatta aaagaagcgc aattaaaaga aggcgaaatc gaacaattag aaatcgatat
    14221 taaacgtatt cagaactccg aaaacttaag tttagcattg aacgctgctt atgtgacttt
    14281 aacggatgaa catgcgatta cagatcgcct ttatacttta agctcagaat tacaaaatgt
    14341 gaatcaaatt ttacctgaaa cgtttgaaaa gctaaaagaa gaagttgatc aattttatta
    14401 cacgttagaa gatgctaaac atcaaatcta tgaagaaatc aaccaaactg aatttgatga
    14461 acaatattta aatgaactcg aatcacgaat gaacttgttg aacaatttaa aacgcaaata
    14521 cggcaaagat atttcagatt tgatgattta tcaagaaaaa atcgctgatg aaattaataa
    14581 aatcgaaaat tatgaagaaa gtacctcgaa actacgtgaa gaaatccaac aattatcgca
    14641 acaagttcag gaagatgggg aaaagttagc aaaagcgcgt agaatagtag caagacagtt
    14701 gcgcgatcgt attgtcaatg aaatccaata cttacaaatg aaggatgcga atttagaaat
    14761 ttcgtttaaa ccttatgaaa caccgcaaaa agatggttta gaacgcattg aatttttaat
    14821 tagcccaaat aaaggtgagc cattaaaaag tttgaacaaa attgcaagtg gcggtgaact
    14881 gtcacgaatt atgctcgcac tgaaaagtat ttttgtacgc gcacacgggc aaactgcgat
    14941 attatttgat gaagtggatt ccggtgtttc tggacaagcg gcacaaaaga tggctgaaaa
    15001 aatgaaagac attgcttcag ttattcaagt catctgtatt tctcacctac cacaagttgc
    15061 gtcaatgagt gatcatcatt tgtacatttc aaaacatgag aaagatgacc gcaccactac
    15121 aactgtacgc gaacttacag gtgatgcacg gatagatgaa attgcacgca tgatttcagg
    15181 tgcaactgtt accgaattga caagagaaaa tgcgaaagaa atgattgaac aaaaccaaaa
    15241 gcacaaagga tgatgaaagt tgaattttac agacttgctt aaagaacctc aagctctaac
    15301 agggacaatt gcgattgtta atgcaacgga tgaaccactt attagagtca ttattgaagt
    15361 tttaaagcaa accgaagctg acttcaaact ttataataat caagatgtag ctgaaatcat
    15421 tcgttcattt gatttgtcgg ccgacttttt aaagcgtatc catattcaaa cttttgatac
    15481 agaagaggct gcaattgaag gttgcttaaa tgatttgtat catggcaaag cacaaatttt
    15541 gatgaaaggg caaatttcaa ctgctaaaat cttatctgcg gtattaaaac gtaacgcaca
    15601 aggtacaaaa ccttttttaa accatgtggc gttatgtgaa atcccgtcgt atcacaaact
    15661 gcttatgatt tcagacgttg cgctcaatat tgcgccaaca gaagaagaga tgaaagccat
    15721 tattcaaaat ttggttgatt tttcaaaaag gctacaatat caacaacttc acattgcatt
    15781 attgtcatcc gttgaaaagg tcagccctaa aataccatct accgttcaag ctgagcgttt
    15841 aagtgaatat tatcaatcac atcctattga accgcatgtg catgttgaag gtccatttgc
    15901 gttagataat gcgattgata aaaagagtgc gattcaaaaa ggtatccatt caaaagttgc
    15961 agggaatgca gatgttctta tagttccagg attagatgca ggcaatgtat tatataaatc
    16021 actcacatat tttggtcgtg caaaagttgc gagtcttatt ctcggcgcac attttccaat
    16081 cgttcttaca tcaagagcgg acagtattga aaataaaatc aactctattt tagtcgcatt
    16141 aaaagtcggt taaccttgta aacaaaatat gggaccggga tattgagttt tcccagtctc
    16201 tatctatatt atggacgcaa atccattaat gatgataaaa aagtcaaaaa atgtggatga
    16261 attggatatt attgtttgtc ctcattctat caacttgcct taagttgttg caattgatgt
    16321 aagtttgacc aaaaggctaa gacgcttaag agattgcgtg tatactgcta gcgttcactt
    16381 ctttacttta atagtggtta ctgtttatca cagtagctgt ctgccttctc aaggcgcatg
    16441 tttttcagat gtcgagtcag ccatccgggt cagtgcgacg aaatctttat gatacatgag
    16501 atttctgtac tgctcccata atccactaac acctcaacaa atgtaacagt ttaatcaagc
    16561 gttagtgagt tgaagggcaa acccatagga acaccaagac atgaaggcaa tcaaaaacac
    16621 aattcgtaaa gagagcaagt taaactataa tattgcgact atagcatctg aagttttgtt
    16681 ctccatctcc atacattttt gatttgtttt tgaaagaagg gattgtatga caacaacact
    16741 cgtattaaat ttagggagta cctctagtaa atatgcaata tatgaaaatg atgaatgtaa
    16801 agtaaatgaa aatatcagcc acactgaagc tattttaaag caacccttaa ttgatcaaga
    16861 gtcattgaga caacaattga ttgaagatga aatcgaatca caggggtatc agttgaatca
    16921 aattgatgcc attgcctgtc gtggcggtct actcaaacca cttgaaggcg gtacatattc
    16981 agtaaacgaa gcaatgtatg acgacttaaa aagctttaag tatggcgccc atgcttctaa
    17041 tttaagcgcc atgattggtt atcaacttgg ccaaaaatac catatcccag tttttacgac
    17101 tgatccggtt gtcgtagatg aattgatcga tgaagtacgc catactggag tgccgtccat
    17161 tcaacgtcga agtatctttc atgcattaaa tcaaaaagcg atggctcgtc gttatgccgc
    17221 actagtcaat cgtgcttatg aaaatatgaa tgtgattgtg atacatatgg gagggggcat
    17281 cagcattggt gcgcatgaaa aagggcgtgt cattgacgtg aatgaagcat tatatgggga
    17341 aggtccaatg gcaatggatc gttctggcag cataccaaat gatttactag tccaatacat
    17401 ggagaagcat cagttatccg ctgatgaaat caaggtgcag ttaagtcgtg agtctggact
    17461 taaagcatat tttcagacat ctgatttaag agaaattatg gccaagtatg agcaagatga
    17521 aaatgtgaag ttaattatcg acacaatggt gattcaaatc gccaaagtga ttggagaacg
    17581 tgctgtcgtt ttaaaaggac acgtcgatca aattattttt acaggcggta tgagccatag
    17641 tgttcaatta atggatcagc ttgcgaagta tatagagtgg attgctccaa tttcagtttt
    17701 cccaggagag catgaactta tcacgcttgc agaacgtgca caattagcat tgaatcagca
    17761 aattaaaatt gagatatatc aataggagaa aacatatgac aaaagaaaaa tacgatatcg
    17821 ttatccttgg cgggggtatt gcgggatatt ctgctgcaat ccgcgcgagt caacttggaa
    17881 aatctgttgc tatagttgaa aaatcaaaaa tgggtggaac atgtttgcat caaggctgta
    17941 ttccaacaaa atcttttctc aaatcagcag aggtctttca atacgtacaa catgccgatg
    18001 actttggtgt gactgctgaa ccaccgacgt ttaatttctc aaaagtgatg gaacgtaaaa
    18061 atcgcatcgt cgacacaatg tatcaagggc tacaagggtt aatgaaacgt cacaaaattg
    18121 atgtatttca tggcgttggt cgcctaatgg gtgcttcaat ttttacacct caaagtggca
    18181 cagtttctgt agagtatgaa gacggaacat ctgaactatt accgaatgac tatgtattaa
    18241 ttgcaacagg atccaaacct atggcactgc cgtttttacc gtttgatcaa caacaaatat
    18301 atagtagtaa tgatatgatg acgcttgaag ctttaccaca atccatcacg attattggcg
    18361 gcggtgttat cggattagaa tttgcatctt tctttagtag tgtaggtgtc acggtacata
    18421 ttatcgaagc tggtccacgt attttaccaa cagaaaatgc acaaatcagt caattaattc
    18481 aaaaacaatt ggaagagcaa ggtgtcaatt tccatatcaa tacggtgctc aaaggagacg
    18541 acatccaaca aagcgacgag gaagtgacct tcaatcttga aaaaccattc tccactgaaa
    18601 aagtactcgt tgctattggt cgacaagtga atacagcgga tttaggttta gacaatacga
    18661 aagttgtatt gaatgacaag caaatgatcg aaacgaacga atatatgcaa acggctgata
    18721 cacatattta tgctgctgga gatgtaatcg gccatttaca acttgcacat gtcggagcta
    18781 gagaaggtgt gattgccgtt gaacatatgt ttaatgaaaa tccactaccc gttgattatg
    18841 atttgatgcc aagatgtgtt tatacatcac ctgaaattgc gtcaatcggt gttaatcaag
    18901 aaacagcaaa acaacgcggt cttaaatttg aagtcatgaa agcaccgttt aaagcgaatg
    18961 gtaaagcaac gattactact tcatcaactt ctgaaggctt tgctgaacta ttgtttgatc
    19021 aagcatctgg tagtttgatc ggtgcatctt taattggtcc tcatgttaca gagctcatca
    19081 acgaattaag tgttttacaa tttatgaatg gttctgcact tgaattagga ctttcaacac
    19141 acgcacatcc gtccatttca gaattactca tggaattagg attaaaatct aatcatcaat
    19201 ctattcacat atagataaga aggaggaaaa tagatatgaa agattatcaa agtgttggcc
    19261 ttgaaattga agatttaaaa aacatgtacc gtgctatgga tttaggccgt aagttagatg
    19321 aaagaatgtg gctcttaaat cgtgctggga aaattccatt cgtcatcagt tgtcaaggtc
    19381 aagaagccac acaaatcgga acggcttatg ctttacaaaa aggagacatt acatcgcctt
    19441 attatcgtga tttagcatta gttacttatt taggtatgac acctttagaa acgatgttat
    19501 ccgcttttgg taaacgtgat gacatcagtt ctggaggtaa acaaatgcca tctcacttca
    19561 gtaaaaaaga agtcggcatt atgtcacaag ggtcttcagt ggctacacaa atcctccatg
    19621 cagtcggtgc agcattaaca tttaagatgg atggcaaatc tcaaatcgca ttaacgacac
    19681 taggtgaggg gagttcaaac caaggtgatt ttcatgaagg gttgaatttt gcaggcgtcc
    19741 ataacttacc atttatttgc ttaattgaaa ataataaata tgcgatttct gtatctaaag
    19801 aattccaata tggtgcaaaa tatttatcag atcgtgcgaa aggatatggc atgttcggtg
    19861 agacgattga cggtaatgac ccaattgctg tctatggtgc tattaaaaaa gctcgcgaac
    19921 gtgcagtaaa tggtgaaggt gcctcattaa tcgaagccat gtgtacaaga ttaacagcac
    19981 actcttcaga tgatgatgac cgttaccgca cagttgaaga aaaaaatgcg gataaagaaa
    20041 atgattgtaa ccttaaattc aaacaatatt taatcgatca gtcattagtt gatgaaacgt
    20101 ggtttgagtc gattgaaaaa gaaaatcaac agtgggttca tcaagcgact aaagaagctg
    20161 aggccgcacc atacccagat ccatctgaaa catacttaca tgtctatgaa gaaggaggac
    20221 gtcaacatgg ctaaaatttc atatcttgaa gctattagac aagcacttga tgtcgcgcta
    20281 gaaaaagatg cgcaaacgat gattcttggt gaagatgtag gtaaaaaagg tggcgttttt
    20341 ggggtgacag ctggattaca agaaaaatat ggcgtttatc gtgtattaga tacaccactt
    20401 gctgaatcca acattgtcgg ttctgctatt ggtgcagcga tgatggggaa acgtcctatt
    20461 gctgaaatac aatttgcgga atatatttta ccggcgacta accaaattat gagtgaagct
    20521 gctaaaatgc gctatcgttc taacaatgat tggcaggcac cattaacgat tcgcgcacca
    20581 ttcggcggtg gtattcatgg cgcactttat cattcacaaa gtatcgaaag tgtatttacg
    20641 tctactccag gcttaactgt tgtcattcca tccacacctt atgatgcaaa aggcttactt
    20701 ttagcgtcaa ttgcatcaaa tgaccctgtg cttttctttg agcataaaaa ggcatatcgc
    20761 ttactaaaag aagaagttcc agaaggatat tacactgtgc cgcttggtaa agctgatgtc
    20821 aaacgacaag gtagcgatat cacagtattt tcatacggtc tagcagtgaa ctattgtctt
    20881 ca
//
