LOCUS       NZ_CP066300            20858 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Lactococcus lactis strain WiKim0098 chromosome.
ACCESSION   NZ_CP066300
VERSION     NZ_CP066300.1
KEYWORDS    RefSeq.
SOURCE      Lactococcus lactis
  ORGANISM  Lactococcus lactis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 2424276)
  AUTHORS   Kim,T.W.
  TITLE     Genomic analysis of Lactococcus lactis WiKim0098
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2424276)
  AUTHORS   Kim,T.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-NOV-2020) Microbiology and Functionality Research
            Group, World Institute of Kimchi, 86, Kimchi-ro, Nam-gu, Gwangju,
            Gwangju, Gwangju 61755, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FLYE v. 2.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 342.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 08:40:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,477
            CDSs (total)                      :: 2,390
            Genes (coding)                    :: 2,331
            CDSs (with protein)               :: 2,331
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 36 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 12 of 59
            Pseudo Genes (multiple problems)  :: 10 of 59
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:11:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 890076
            Orig. end                         :: 910934
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066300.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20858
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20858
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20858
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10858](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10858
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(313..2409)
                     /locus_tag="LacL0098_RS04405"
                     /old_locus_tag="LacL0098_04405"
     CDS             complement(313..2409)
                     /EC_number="7.2.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015662 - P-type ion transporter activity
                     [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010905590.1"
                     /locus_tag="LacL0098_RS04405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04405"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_200984882.1"
                     /transl_table=11
                     /translation="MSNKTHSSNHEEMMSQHHHNHEMVNMKHENHEMHGMHNMDNMDNM
                     HDMDNMDMMNHGGHMMHMGDMSKKLKVAIILMIPLLLISPIAGFTILKFPGSEILQLIL
                     GTIIFFYSGTPFFSGAKGELKSRKPAMMMLITMGITVAYAYSVYATIMSLNGHMGMNFW
                     FELATLIVIMLIGHLIEMKAIMGAGDALKDLASLVPKKAHLKSGKDVELSELKVGDLLL
                     VKENEKIPADGLILSEALVDESMITGESRAVNKKTNDLVYGGSLNQNQPFEMKVTTLGK
                     DSFLNQVAELVKKAQAQKSNLENMADRVAGYLFYAALIVGIFSLIFWTVSSNFSFALLL
                     AVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLT
                     DGKFIVRNVIDFTDETEILQIMAALEGSSTHPIAQSIVSAAKPLENLKVEAVENIPGVG
                     IKGQVNQNFYQIVNYKYLRENQLSYDEQKIAQYLDLGLTVSFLINEQQDVLGFIALGDS
                     PKADAKAFINGLLAQGITPVMLTGDNKETAQKIASALNIPEFRAELKPEDKAEIVKEYQ
                     KKAGVLFIGDGVNDSPALATATIGFAIGAGTSVAISTADVVLVNSNPSDVLDMINISKR
                     MLRKMKQNLWFGAGYNIIAIPVAAGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLR
                     YDKK"
     misc_feature    complement(2454..2469)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: strong, score: 30.52"
                     /tool="antismash"
     gene            2610..5942
                     /locus_tag="LacL0098_RS04410"
                     /old_locus_tag="LacL0098_04410"
     CDS             2610..5942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015426153.1"
                     /locus_tag="LacL0098_RS04410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04410"
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="WP_200984883.1"
                     /transl_table=11
                     /translation="MKKIRPEVSTVISKSHFRTWKSGKSWLFATSALALIIVSGTITDQ
                     NVKADTAVDSSQQISGITEETSYSALASSTNSDVAASQNQVAYEQASDQSSNNSLANTV
                     ENDTEGMTSDVSDSSNSINESQNTISTAVIQTATNNIVSLADSSSSNDNISNSILSSSN
                     AADSVDSAAVSQSSTSSSVILSESSAIDSGIGSTSQSSEINLAENSSANGSSAAVASFT
                     AILATNSSVVPMLTQALAAAAPATTSGSAILNTTLGDLVNQAISTVGISGLENILNTLG
                     TFNIPGMTTAASALNGVEQIVNIVGNIQEAAANPGAFLLNGMKSAGLDVSQIPLVGGQI
                     VAAFNAIPSMSPAAMLNFLENPTIPGLSSIPGANLVLSPVLSAISTVTSGIVNQLNTTT
                     SNALGGVNFDIDTLVSLQGNDLVNYLAGLVVNSAINRAGQIAWSQLSPTISNIPLVGTT
                     VNNVLSPILNNLTGASLGEVANLTGVSSLLDQVNNSLGNFTSLGSTALATIENTLQNSL
                     NSLGNLPAGASDILNQVLNQLQNAINNIVESATGIVNNLPSLGAIENDLSNTISQIQNS
                     DILNQVVNQLQSAINNIVESATGIVNNLPSLGAIENDLSNIISQIQNNVNNFVNNALNG
                     ITTIINSLTPSVGASTVNPNSSANSSQSSSSASSSSSAASSSTSSSNVSSNTSSNSSEA
                     NTSSSSSEGSSTSSSNSSESSVASSSSVDSSQTSSAGANSSNSSSEGSSASSSNSSEGS
                     ATSSSSVDSSQSSSAGVNGSSSSSEGSSISSSNSSESSIASSSSVDSSQSSSAGVNSSS
                     ASSEGSNASSSTSSESSTASSSSVDSSHSSSAGVNGSSSSSEGSSASSSTSSESSTASS
                     SSVDSNHSSSAGVSSSDSSSEGSSVSSSTSSESSTASSSSVDSNHSSSAGISSSSSSAE
                     GSSVSSLSSSESSITNSSGTSDSNSNTDQTSITSPSSENSSQSSLSSNESSSASLTSSE
                     SSGSTTSSSMLTNPNLQANDKNGSSLISNSSYTSEMKLNNLSDSNLPSNEAKVSTLISK
                     VSSSPSLSNSLSATSLQLVPTVTKEELPKTGADDDLSLVLAELGLGLVATLTIGKVKYK
                     KRF"
     gene            6101..6955
                     /locus_tag="LacL0098_RS04415"
                     /old_locus_tag="LacL0098_04415"
     CDS             6101..6955
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131344.1"
                     /locus_tag="LacL0098_RS04415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04415"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_038602888.1"
                     /transl_table=11
                     /translation="MNLIDGKALAAKMQAELKVKVDKLKEADNVPGLAVILVGEDPASQ
                     IYVRNKARQATAIGLNSSVVRLPETVTEQELLDLIEQYNQSEQWHGILVQLPLPEHISE
                     EKVLLAIDPEKDVDGFHPMNMGRLWSGNPLMIPSTPAGIMEMFREYNVELSGKRAVVIG
                     RSNIVGKPMAQLLMMADATVTIAHSKTENLRELTKEADILVVAIGRDRMIKAEDIKEGA
                     VVIDVGMNRDEDGKLHGDVDFDEVKNVASFITPVPGGVGPMTITMLMEQTVRAASRKMN
                     ENK"
     gene            7122..8375
                     /gene="xseA"
                     /locus_tag="LacL0098_RS04420"
                     /old_locus_tag="LacL0098_04420"
     CDS             7122..8375
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131345.1"
                     /locus_tag="LacL0098_RS04420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04420"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_038601482.1"
                     /transl_table=11
                     /translation="MTEYLSVSTLTKYLKAKFDRDPYLERVYLTGEISNFRRRPNHQYF
                     ALKDEGAVIQATMWAGQFRKLDFELEEGMKVLAVGRISIYPPSGSYSLNIESLVPDGVG
                     ALAVKFEQLKKKLTAEGLFEQRWKQTLPQFSKKIAVVTSPSGAVIRDIITTVQRRFPMS
                     QIVLYPTKVQGQGSAEEIAENIRRANERGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIF
                     ESRIPIISSVGHETDVTLADFVADSRAATPTAAAELATPNTKVDLINWANEQEKRLFNR
                     LTHLIKIRRERVDKLSQSVVFRQPERLYDGHLQKLDRLCERLSVLTENKVANMKHRYEL
                     SAGKLIPTYGKIVEAKKNKTEQLYQSLLLLDISKIKARGFSLVTDEKGKIIKSVSDVKK
                     GQTLDVELTDGKVIVEVK"
     gene            8375..8614
                     /locus_tag="LacL0098_RS04425"
                     /old_locus_tag="LacL0098_04425"
     CDS             8375..8614
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131346.1"
                     /locus_tag="LacL0098_RS04425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04425"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_003131346.1"
                     /transl_table=11
                     /translation="MATKKEDVKFEDNLAELENIVRKLESGDVALEDAIAEFQKGMKIS
                     ETLKKTLNEAEETLVKIVGKNDQESDFSPEQKDY"
     gene            8763..9920
                     /locus_tag="LacL0098_RS04430"
                     /old_locus_tag="LacL0098_04430"
     CDS             8763..9920
                     /EC_number="2.7.1.31"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864361.1"
                     /locus_tag="LacL0098_RS04430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04430"
                     /product="glycerate kinase"
                     /protein_id="WP_038601481.1"
                     /transl_table=11
                     /translation="MKKKFVLAPDSFKESLSALEVCQAMEKGIKKVFPEAEIISMPMAD
                     GGEGTTDALIDATGGRRVYKKVQGSFANTNVEAYFGILGNSNTAVVEMAKANGLELVAL
                     EDRNPLITSTYGTGQLIKAAMDEGVDKIIIGIGGSATNDGGSGMARALGARFLNKDQEE
                     IPLGGAFLKEVRTIDMSDFDPRVEEIEILIATDVTNPLTGNNGASYVFGPQKGATEEMV
                     KVLDENLKHYAEIVHNNLGKDVKNIPGAGAAGGLGAGLLAFTNAKMQLGIELVAQTIYL
                     EDKIKEADYVFTGEGGMDYQTKFGKAPYGVCKIAKKYKKPCFALAGYIGDGAEVLYEEG
                     MTAIFGILSQAQSLSDALADGAKNVERTSQNITRVLAMNEQKAHL"
     gene            10001..10858
                     /locus_tag="LacL0098_RS04435"
                     /old_locus_tag="LacL0098_04435"
     CDS             10001..10858
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012897509.1"
                     /locus_tag="LacL0098_RS04435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04435"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_038601480.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.3e-53, bitscore:
                     177.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKIRKLEDFLTEFYESAEFPTGLAESAKYSLLAGGKRIRPLLF
                     LNLLEAFNLELSKAHYHVAAALEMIHTGSLIHDDLPAMDNDDYRRGQLTNHKKFDEATA
                     ILAGDTLFFDPFFILSTADLSAEIIVALTRELAFASGSYGMVAGQILDMAGEGKELTLA
                     EIEQIHRLKTGRLLTFPFVAAGIVAQKSTDEVEKLRQVGQILGLAFQIRDDILDVTATF
                     AELGKTPGKDILEEKSTYVAHLGLEGAKKSLTENLSEVKKLLTDLSVTDSSEIFKIIEQ
                     LEVK"
     gene            10859..11353
                     /locus_tag="LacL0098_RS04440"
                     /old_locus_tag="LacL0098_04440"
     CDS             10859..11353
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082272.1"
                     /locus_tag="LacL0098_RS04440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04440"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_038601479.1"
                     /transl_table=11
                     /translation="MDFQIKILTENDRTIIEKFFEKASDYAILESGFSNPQLETESFIN
                     DLPPAKKLTDKFNHGIFDKNNNLVGVIDLIKDFPTKGEFMLGLLEFVPAVRHQGLGKAV
                     HKILIEKVRDLGAKSLRIGVLEVNNSAIKFWKSLGYIKFKEIEQDFGNKKQKIAVMRLK
                     L"
     misc_feature    11410..11423
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.74"
                     /tool="antismash"
     gene            11436..12242
                     /locus_tag="LacL0098_RS04445"
                     /old_locus_tag="LacL0098_04445"
     CDS             11436..12242
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131349.1"
                     /locus_tag="LacL0098_RS04445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04445"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_038601477.1"
                     /transl_table=11
                     /translation="MKERIDVLATNQGLFETREQAKRGVMAGLVVDSKSGERYDKPGQK
                     IDDGTELRLKGEKLRYVSRGGLKLEKALKEFHLEINGKTCLDIGSSTGGFTDVMLQNGA
                     KLVYALDVGTNQLAWKIRSDERVVVMEQFNFRNAVLADFGQGRPSFTSIDVSFISLDLI
                     LPPLYEILEENGEVAALIKPQFEAGREQVGKNGIIRDSKVHQMTIEKVLKTATQLGFSV
                     KGLTFSPIKGGAGNVEFLVHLLKDGKAEIAQQVNIESVLQKESEEL"
     gene            12239..12685
                     /locus_tag="LacL0098_RS04450"
                     /old_locus_tag="LacL0098_04450"
     CDS             12239..12685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015426160.1"
                     /locus_tag="LacL0098_RS04450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04450"
                     /product="arginine repressor"
                     /protein_id="WP_038601476.1"
                     /transl_table=11
                     /translation="MKREDRLNFIAQFIRENEIKTQEELVNTLLTHGIDVTQATVSRDI
                     KSLALIKVPAESGGYRYDLPKNKEVLQSSLHKALAFDAITGTKIKDNMLWILANPGTTS
                     LVKNYLLEEYGDDIFSIIIDDNSALVIFEMEEDAKNLYNLLTEF"
     gene            12834..14501
                     /gene="recN"
                     /locus_tag="LacL0098_RS04455"
                     /old_locus_tag="LacL0098_04455"
     CDS             12834..14501
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019292004.1"
                     /locus_tag="LacL0098_RS04455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04455"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_038601474.1"
                     /transl_table=11
                     /translation="MLQEISIKNFAIIEEIHLSFESGMTILTGETGAGKSIIIDAMSLL
                     LGGRASSDFVRHGATKAEIEGLFFFDKTPELKAVLLELGFEEVDSEIILRREIFANGRS
                     VCRINGQMVNLATLRQVGELLVDIHGQHDSQELMNPKSHLRLLDEFGDEAFDAIKDNYK
                     LKFENFKNLRQQLNLRQKNEQEFAQRIEILQFQAEEIEAAEINLEEDEQLVNRREKLNN
                     IKNIADSLSSAYLALDDEDNDYSSLNNIRTTMTELDKISNFDNDYQELADKTAESYYVL
                     EEVANQIQRIMSDLEFNPAELLQIEDRIMTLTTLKKKYGPELSDVMNYLEKVQLELSEL
                     TGSEKDSENLENSVKVAQVQLIEASKKLNEARHKIAKEVEKDIKHELSELYMEKADFKV
                     SFEGAKFSANGNEHVEFFIQTNPGEGFKPLAKTASGGELSRLMLAIKSSFSRRENKTAI
                     VFDEVDTGVSGRVAQAIANKIYKIARHGQVLAISHLPQVVAIADRQFYIEKASTDDITT
                     STVRKLNFDERVNEIAKMLAGEDLTKEALAQAKRLLSK"
     gene            15226..15792
                     /locus_tag="LacL0098_RS04460"
                     /old_locus_tag="LacL0098_04460"
     CDS             15226..15792
                     /GO_process="GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011675826.1"
                     /locus_tag="LacL0098_RS04460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04460"
                     /product="TMEM175 family protein"
                     /protein_id="WP_038601472.1"
                     /transl_table=11
                     /translation="MSKTRLEAFTDAVIAIIMTVLVLELVRPDSDSLQSFIALLPHLGV
                     YFVSFFILAIYWVNHHHLFQSIKRINGKVLWINISFLFVLSLIPIFSNWVSIYPNSFIP
                     ELGYVIIFFLGNFIYLLLTRELLKINGHRKTSETTIRKNILSVVLNIVSILLGYFIAPV
                     IMLVGSALIFSMWVIPDKNIEKMFK"
     gene            15890..16411
                     /locus_tag="LacL0098_RS04465"
                     /old_locus_tag="LacL0098_04465"
     CDS             15890..16411
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015426163.1"
                     /locus_tag="LacL0098_RS04465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04465"
                     /product="DUF805 domain-containing protein"
                     /protein_id="WP_038601470.1"
                     /transl_table=11
                     /translation="MIKAYIKYWKKAGDLKSYSNRSDYWWVFLTNSIIFAILSILNFMV
                     TIPKAGKIMSQSATLSQKEIIQQVTDLYANPTGGALVIVIVTALIGLAILVPDISLTAR
                     RLRDARFPWWIALIFGVAAIYGLVTMFIHQDFLAKMGYFVGFINFIIYILCLFPTKYGI
                     DEEDDSRTYE"
     gene            16435..17373
                     /locus_tag="LacL0098_RS04470"
                     /old_locus_tag="LacL0098_04470"
     CDS             16435..17373
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864363.1"
                     /locus_tag="LacL0098_RS04470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04470"
                     /product="DUF805 domain-containing protein"
                     /protein_id="WP_118263399.1"
                     /transl_table=11
                     /translation="MVQAYKKFWLGAFTFNRKTSRKDFWSALLTHIIIFVILFKAYHFF
                     NLLDFYQLTTLWQTFASFFQLVFNLYFFGSLLSFIALTVRRLNDADLPWALIFLNFILG
                     LGTLVLLVLNLLPSSPRALKFEEYKINSSQEFNNLPETKTLSGIFKDYFKNYFEFRGRT
                     TRRNFWWMQLFWGLTFILFLFLIYLFNQFEQIMFGYNFIGSIVLRLFFFLFILGTFFPQ
                     LTIHVRRLRDAGLSNLGLSLLLGGTSGILIFYQMFTKALKITYITGHYQLVQYLLFLLV
                     MIAVLSLILVEVMATGELKTNKKNSLFEKID"
     misc_feature    complement(17496..17509)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.27"
                     /tool="antismash"
     gene            17593..18546
                     /gene="rsmH"
                     /locus_tag="LacL0098_RS04475"
                     /old_locus_tag="LacL0098_04475"
     CDS             17593..18546
                     /EC_number="2.1.1.199"
                     /GO_function="GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864364.1"
                     /locus_tag="LacL0098_RS04475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04475"
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="WP_200984884.1"
                     /transl_table=11
                     /translation="MPKTIAFKHDTVLLHETVDMLEVKPNGIYVDATLGGAGHSEYLLS
                     KLTDGHLYSFDQDETAHENAKVRLSEQLAEDKVTLIKSNFRYLKSALAEVGVTKIDGIL
                     YDLGVSSPQFDDSQRGFSYKKEARLDMRMDQNQTLSAYEVVNDYPYEALVRIFFRYGED
                     KFSKQIARKIEQARKIKPIETTIELADLIKSALPQKELKKKGHPAKRIFQAIRIEVNDE
                     LGAAEESIEQAIDLLKVDGRISVITFHSLEDRLTKTIFKEYSTVNVPKGLPMLPKDMEA
                     KLKLVNRKPVLASEEELEFNNRAHSAKLRVAQKQRD"
     gene            18711..19091
                     /locus_tag="LacL0098_RS04480"
                     /old_locus_tag="LacL0098_04480"
     CDS             18711..19091
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131357.1"
                     /locus_tag="LacL0098_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_04480"
                     /product="cell division protein FtsL"
                     /protein_id="WP_003131357.1"
                     /transl_table=11
                     /translation="MAAQPKEYFDIETAAKKDSYLIDTETLAPEVLASKFKKFSGVEKV
                     FYLTMVVAALVLAVGLLYVKTKTLEVQGNTMDLRSKISQETTRKTEYDQQILDLTSGTK
                     VLDTANKADLKQNPSNVLKATK"
ORIGIN
        1 ttgattctaa tgagattaga ttggaaataa aaaaactgct tcaagatact aaagattatt
       61 tacttcaagg agtctttgat gtttttgatg ctaatcgtta tcttagaggt aatatttatt
      121 ttttagttca tcaagggagt caattaaatg attatgaacg aaagattcta aaatcattta
      181 aaaataaatc atatttaaaa aatatcatta caatcattag tatttgtgtg atatcatact
      241 taatctttaa gtatatttaa gtgataaaag tttcataatt agtatgaaaa aaatagaaga
      301 gcatgtgctc ttctattttt tatcatacct caatcccatc gcgttgattg agacaatcac
      361 ggttgagatt gacatcagga ctgctgcaat gagagggtca atataaatcc ctgtaaatgg
      421 ataaagaata cccgctgcaa caggaatagc aataatgtta tagcctgctc caaaccagag
      481 gttttgtttc atttttctaa gcatgcgttt ggagatatta atcatatcca ggacgtcact
      541 tggattggag ttaactagga cgacatcagc ggtactgata gcaaccgaag ttcctgctcc
      601 aatcgcaaaa ccaatcgttg cagttgcaag agctggggaa tcattgacac catcaccaat
      661 gaaaagaacg ccggctttct tttggtactc tttcacaatt tctgctttat cttcaggttt
      721 taattccgct ctaaattcgg gaatatttag tgcactagca attttttgag cagtttcttt
      781 attatcaccc gtgagcataa caggggtaat tccttgggct aataaaccat taataaaggc
      841 tttcgcgtct gctttaggag aatctcctaa ggcaataaat cctaaaacat cttgttgttc
      901 attgattagg aaagatacag ttaaacctaa atctaaatat tgagcaatct tttgttcatc
      961 ataagaaagt tgattttcac gaagatattt atagttaaca atttgataaa agttttgatt
     1021 aacctgccct ttaattccaa ctcctggaat attttcaacc gcttcaactt ttagattttc
     1081 aagaggttta gcagctgaaa cgattgattg agcaatcggg tgagtggaac ttccttcaag
     1141 tgctgccatg atttggagaa tttctgtttc atcagtaaaa tcaataacat tacgaacaat
     1201 aaacttaccg tcagttaatg ttcctgtttt atccattaag gcatatttaa ttgtatttat
     1261 tttttctaga gaagttctgt tttgaattaa taaaccattt ttagcagaaa tactggttaa
     1321 gcgagaaaca acaagtggaa ccgcaagacc taaagcgtgt ggacatgcaa ttacaaaaac
     1381 agaaaccgca agaagtagag caaaactaaa gttagagcta actgtccaaa aaattaatga
     1441 gaagataccg acaataagtg cagcatagaa aaggtaacca gccactctgt cagccatatt
     1501 ttccaaatta gatttttgag cttgggcttt cttgactaat tcggccactt gattgagaaa
     1561 tgaatctttt ccaagggttg tgactttcat ctcaaatggt tggttttgat tgagggaacc
     1621 accataaaca aggtcatttg tttttttatt gactgctcgg ctttcaccag taatcattga
     1681 ctcatcaacg agcgcttcac ttaatataag gccatctgca ggtattttct cattttcttt
     1741 cactaaaagt aaatcgccaa cttttagttc tgaaagctcc acatccttcc cactttttaa
     1801 gtgagctttt ttgggaacaa ggcttgctaa atctttcaat gcatcgccag cacccatgat
     1861 tgctttcatc tcaatcaggt gaccaatcaa cataataaca attaaagttg ccagttcaaa
     1921 ccagaagttc atgcccatat gtccgttaag actcatgatt gtggcataaa cagaataagc
     1981 ataggcaacg gtaattccca ttgtaatcag catcatcatg gctggcttac ggctttttaa
     2041 ttcacctttt gctccgctaa aaaaaggagt cccagagtaa aagaaaataa ttgtaccaag
     2101 gatgagttgt aaaatttcac ttccggggaa tttaaggata gtaaagccag cgattggtga
     2161 aatgagtaga agcggaatca ttagaatgat agccactttg agctttttac tcatatcacc
     2221 catatgcatc atgtgtcctc catgattcat catatccata ttgtccatat catgcatatt
     2281 atccatatta tccatattgt gcatgccatg catctcatgg ttttcgtgct tcatattcac
     2341 catttcatga ttgtgatgat gctgagacat catttcttcg tgattagacg aatgagtttt
     2401 atttgacata ttttcctcct aaatgaatgc tttgaaattt ctatctatat atagtttaca
     2461 tttgtaaact atcaaagtca aggaaaaaag ttgtattcta taaatgttac gaaataacaa
     2521 tagaaaggtt tcttttgtaa cttaaatgtg atatcatgat atataatcat agtgatactt
     2581 tataaaaagt atcagcaagg agagaataaa tgaaaaaaat acggccagaa gtgtctactg
     2641 ttatctccaa gtcccatttt agaacctgga aatcagggaa aagttggtta tttgctactt
     2701 cagcattagc tttaattatc gtttcaggaa cgattactga ccaaaatgta aaagcggaca
     2761 cagcagttga tagtagtcag caaattagtg gtattacaga agaaacaagt tattcagcac
     2821 tagcttcgtc gacaaatagt gatgttgctg ctagtcaaaa tcaagttgct tacgaacaag
     2881 ctagtgacca aagttctaat aattcactgg ctaacacagt agaaaatgat actgagggaa
     2941 tgacttcaga tgtttcagat agtagcaact caattaatga aagccaaaat acgataagta
     3001 cagcggttat tcaaactgct acgaacaata ttgtatcact tgctgattca agctcatcaa
     3061 atgataatat cagcaattct atattaagtt cttctaatgc tgcagacagc gttgattcgg
     3121 cagctgtctc tcaaagttca acaagttcat cagtaatttt gagtgaaagt tcagcaattg
     3181 atagtggtat tggatcaact tctcaaagtt cggaaataaa tcttgcggaa aatagtagtg
     3241 ctaatggttc aagtgctgct gttgcttctt ttacagctat tctagcgact aattcgtccg
     3301 tggtaccaat gcttactcag gcactagctg cagcagcgcc tgctacaaca agtggttcag
     3361 ctattcttaa cacaacactc ggagatcttg taaatcaagc aatttcgaca gtgggaatta
     3421 gtggtttaga aaatatttta aacactcttg gaacttttaa tattccagga atgactacag
     3481 ccgcgtcagc tcttaatggt gttgaacaaa ttgtcaatat tgttggaaat attcaggaag
     3541 ctgctgctaa tcctggggcc tttctattaa atggaatgaa atctgcaggt ttagatgtta
     3601 gccaaattcc attagttgga gggcagattg tggcggcatt taatgccatc ccatcaatga
     3661 gccctgctgc tatgcttaat tttcttgaaa atccaacaat tccaggactt tcaagtattc
     3721 cgggggcaaa tctagtacta agcccagtac ttagtgcaat aagcactgta acaagtggga
     3781 ttgttaatca acttaatacg acaacttcca atgccttggg tggtgttaat tttgatatag
     3841 acacacttgt ctctcttcaa ggaaatgatc ttgtcaacta cttggctggt ttagtagtta
     3901 attcagcaat taatcgagca ggtcaaattg cttggagtca attatctcca actattagta
     3961 atattcctct tgtaggtact acagttaata atgttttaag cccaatatta aataatctta
     4021 ctggagcatc tttgggagaa gttgcgaatt taacgggagt ttccagcctt cttgaccaag
     4081 taaataatag tttgggtaat tttacaagcc ttggttcaac agccttagcc acgattgaga
     4141 acacgctcca aaatagtcta aactcacttg gtaatcttcc tgctggtgct tcggatattc
     4201 ttaaccaagt gctcaatcaa ttgcaaaatg cgatcaataa tattgttgaa agtgcgacgg
     4261 ggattgtaaa taacttacca agtcttggag ctatcgaaaa tgacctttcg aataccatta
     4321 gtcaaataca aaattcggat attcttaacc aagtggtcaa tcaattgcaa agtgctatca
     4381 ataatattgt tgaaagtgcg acggggattg taaataactt accaagtctt ggagctatcg
     4441 aaaatgacct ttcgaatatc attagtcaaa tacaaaataa tgttaataat tttgttaata
     4501 atgcacttaa tggaataacg acaattatca attctttaac tccaagtgtt ggtgcttcaa
     4561 cagttaatcc aaattctagt gctaatagta gccaatcaag cagtagtgcc agttcttcat
     4621 caagtgcagc tagtagttca acttcatctt caaatgtatc aagcaacacg agttctaatt
     4681 ctagtgaagc aaatacttca agttcaagct cagagggttc aagtacttca agttcaaatt
     4741 ccagcgaaag tagtgttgcc agttcatctt cggtggactc aagtcagaca agttctgctg
     4801 gagcaaatag ttcaaattca agctcagagg gttcaagtgc ttcaagttca aattctagtg
     4861 aaggtagtgc cacaagttca tcctcggtag actcaagtca atcgagttca gctggggtaa
     4921 atggctcaag ttcaagctca gagggttcaa gcatttcgag ttcaaattcc agtgaaagta
     4981 gtattgctag ttcatcttcg gtagactcaa gtcagtcaag ttcagctggg gtaaatagct
     5041 caagtgcaag ctcagaaggt tcaaatgctt caagttcaac ttccagtgaa agtagtactg
     5101 ctagttcatc ttcggtggac tcaagtcact caagttcagc tggagtaaat ggctcaagtt
     5161 caagctcaga gggctcaagt gcttcaagtt caacttccag tgaaagtagt actgcaagtt
     5221 catcttcggt ggactcaaat cactcaagtt cagctggggt aagtagctca gattcaagct
     5281 cagagggatc aagcgtttca agttcaactt ccagtgaaag tagtactgca agttcatctt
     5341 cggtggactc aaatcactca agttcagctg ggataagtag ctcaagttca agcgcagagg
     5401 gctcaagcgt ttcaagttta agttcaagcg aaagtagtat tacaaattct agtgggacaa
     5461 gtgattcaaa ttcaaatact gatcaaacta gtattacaag tccctcttct gaaaattcaa
     5521 gtcaatcgag tctgagttca aatgaatcaa gtagtgcaag tttgacttca tctgagtcaa
     5581 gtggttcaac aacatcttca agtatgttga ctaatccaaa tttacaagct aatgataaaa
     5641 atggctcaag tttaatttcg aatagttcgt atacttcaga aatgaaacta aataacttga
     5701 gtgactcaaa tttaccttcg aatgaagcaa aagtttcgac tttaatttct aaggtatcaa
     5761 gtagtccaag tctttcaaat tcattaagcg caacgagctt acaacttgta ccaactgtaa
     5821 cgaaagaaga acttcccaaa acaggtgctg atgacgattt aagtttagta ttagcagaat
     5881 tgggattagg cttagtggca acgttaacta ttggaaaagt taaatataaa aaaaggtttt
     5941 gagtattata ttataattaa ggaattcttt tctttggaaa gaagtttctt tttaatttat
     6001 aaattcttcc tttattaaaa ttacgaacaa tttaaaataa agaaagaaaa agaatgatga
     6061 tgattagagg atgaatgttg gcttatggta taatagttct atgaacttga tagatggaaa
     6121 agcacttgct gctaaaatgc aagctgagtt gaaagttaaa gtcgataaat taaaagaagc
     6181 ggacaatgtt ccaggtcttg ccgttattct tgtgggcgaa gatcctgcga gtcaaattta
     6241 tgtccgaaat aaagcacgac aagccacagc aattggatta aattctagtg tggttcgtct
     6301 accagaaaca gtgacagaac aagaactgtt agatttaatt gaacagtata atcaatcaga
     6361 acaatggcat ggtattttgg tacaattgcc attgccagaa catatttctg aagaaaaggt
     6421 tttactagct attgatccag aaaaagatgt ggatggtttt cacccaatga atatgggacg
     6481 tttgtggtct gggaatcctc tgatgattcc ttcaactcca gccggtatta tggaaatgtt
     6541 ccgtgaatat aatgtggaac tttctggtaa acgtgcagtt gtgattggtc gttcaaatat
     6601 cgtcggaaaa ccaatggcgc aattattaat gatggctgat gctactgtga caattgctca
     6661 ttcaaaaaca gaaaacttgc gcgaattgac taaggaagct gatattttgg tagttgctat
     6721 tggccgtgac cggatgatta aagctgagga tatcaaagaa ggtgcagttg taattgatgt
     6781 tggaatgaac cgtgatgaag atggaaaact tcatggtgat gttgattttg atgaagtaaa
     6841 aaatgttgca agttttatta ccccagtacc tggtggagtt ggtccgatga cgattacaat
     6901 gctcatggaa cagacagttc gtgcagcaag tagaaaaatg aacgaaaata aatagttaat
     6961 taataaaaga gtaactaagt ttatagtaat ttctaaggac ttatttttaa gttagaagtt
     7021 ttttgaagat aaacttttta ctttttttcg attttagcag tagaaatctt actaacagaa
     7081 tgattagtaa aaagtttaat taagaactaa agagtgaggg aatgacagaa tatttatcag
     7141 tatcaacctt aacaaaatat ttaaaagcga aatttgaccg tgatccatat cttgaacggg
     7201 tttatttgac aggagaaatt tcaaatttta gaagaagacc aaatcaccaa tattttgcac
     7261 ttaaagatga gggtgctgtg attcaagcta cgatgtgggc gggacaattt cgcaaattag
     7321 actttgaatt ggaagagggg atgaaagttt tggctgttgg tcgaatcagt atttatccac
     7381 cttctggctc ttattctcta aatattgaaa gtttagttcc agatggcgtt ggagctcttg
     7441 cggttaagtt tgaacagttg aagaaaaaac tgactgctga agggctattt gaacaacgtt
     7501 ggaaacaaac tttgccacaa ttttctaaga aaatagctgt ggtaactagc ccgtcaggag
     7561 cggtcattcg agatattatt acgacggttc aacgtcgttt cccgatgagc caaatcgttc
     7621 tttatccgac aaaagttcaa ggacaaggtt cggctgaaga aattgctgaa aatatccgtc
     7681 gagctaatga acgtggtgat tttgatgtca tgattattgg tcgtggtggt ggttctatcg
     7741 aagatttatg gggatttaat gaagaaattg tggttcgagc aatttttgaa tcacgtattc
     7801 caattatttc atcggttgga catgaaacag atgtgacttt agcagatttt gttgctgata
     7861 gtcgtgcagc gactccaaca gcggcagccg aattagcaac accaaatacg aaggttgatt
     7921 taataaattg ggcgaatgag caggaaaaac gactttttaa ccgcttaaca catttaatta
     7981 aaataaggcg tgaacgagta gataaattaa gccagtcagt cgtttttaga cagccagaac
     8041 gcttgtacga tggacactta caaaaacttg accgtctgtg tgaacgtttg tcagtgctga
     8101 cggaaaataa agttgcaaat atgaaacacc gttatgagct gtcagctggg aaattaattc
     8161 cgacttacgg aaagatagtt gaagctaaga agaataagac ggagcaacta tatcagtctt
     8221 tacttttatt agatatctca aaaataaaag cacgtggttt ttccctcgtt actgacgaaa
     8281 agggaaagat tattaaatcc gtaagtgatg tgaaaaaagg tcagacttta gatgttgaat
     8341 tgactgacgg aaaagtaatt gtggaggtaa aataatggca acaaaaaaag aagatgtaaa
     8401 atttgaagat aatttggcag agttagaaaa tattgttcgt aagttagagt ctggtgatgt
     8461 agcgttggaa gatgctattg ctgaatttca aaaaggaatg aaaatttcgg aaactttgaa
     8521 aaaaacactc aatgaagcgg aagaaacatt agtaaaaata gttggaaaaa atgatcagga
     8581 gagtgatttc tctccagaac agaaagacta ctaaaataaa aaaactttga tttttcaagg
     8641 ttttttattt taaacaaaat tttactgaca aaaaagccta ttattctaat atcaatctta
     8701 tttattatat actaatagta aatagagttg tggtcaagtc ttttatagaa agagtagatt
     8761 aaatgaagaa aaaatttgta ttagcgccag attctttcaa agaaagtttg agtgcgctgg
     8821 aagtttgtca agcaatggaa aaaggaatta aaaaagtatt tcctgaggct gaaataattt
     8881 ctatgccaat ggctgatggt ggtgagggaa caacagatgc tttgattgat gcaacgggtg
     8941 gacgacgggt atataaaaaa gtacagggtt catttgcaaa tacaaatgta gaggcctatt
     9001 ttggtatttt gggaaactca aatacggcgg tcgttgagat ggcaaaggca aatggtctgg
     9061 aattagttgc tttggaagat agaaatccat tgattacatc aacctatgga acaggacaat
     9121 taattaaggc cgcaatggat gaaggagtag ataaaatcat cattggcatt ggtgggagtg
     9181 cgactaatga tggtggttct ggcatggctc gtgctttggg agctaggttt ttaaataaag
     9241 accaagaaga aattccgctt ggtggagctt tccttaaaga agtcagaaca attgatatga
     9301 gtgattttga cccaagagtg gaagaaattg aaatattaat tgctactgat gtcaccaatc
     9361 ctttaaccgg aaataatggc gcttcttatg tttttggacc acaaaaggga gcaactgagg
     9421 aaatggtcaa agtattggat gaaaacttga agcattatgc agaaattgtt cataataatc
     9481 taggaaaaga tgttaaaaat ataccgggag ctggtgcagc aggtggtttg ggagcaggtt
     9541 tgcttgcttt taccaatgca aaaatgcaat taggaattga gcttgttgca caaacaatat
     9601 atttagaaga taaaattaaa gaagctgatt atgtatttac aggtgaaggt ggaatggatt
     9661 atcagacaaa atttggtaaa gcaccttatg gcgtctgtaa aattgcaaaa aaatacaaga
     9721 aaccttgctt tgctttggca ggatatattg gggatggagc agaagttctt tatgaggaag
     9781 gaatgaccgc tatttttggt attttgagtc aagcacaatc tttgtcagat gccttggctg
     9841 acggtgcaaa gaacgttgag cgaacaagtc aaaatattac aagagtatta gcaatgaatg
     9901 agcaaaaggc tcacttataa aaatggaacg gatttaaaaa ataaaaaatt tcctcaaatc
     9961 atcacggttt ttagccgtga attttggtat aattagggta atggatacga agatacgaaa
    10021 gttagaagac tttttaactg aattttatga aagcgctgaa tttccaactg gcttagccga
    10081 atcagcaaaa tattccttat tggcaggcgg taaacgaatt cgccctctcc tttttttaaa
    10141 cctattagag gcttttaatt tagaattgag taaggctcat tatcatgtgg cagccgctct
    10201 tgagatgatt catacgggtt ctttaatcca tgatgactta ccagcaatgg ataatgatga
    10261 ttatcgtcgc gggcagttaa ctaatcacaa gaaatttgac gaggcaactg caattttagc
    10321 tggtgatact ttattttttg accctttctt tatcctttca actgctgatt tatcagcaga
    10381 aataatagta gcgttgacgc gtgaattggc ctttgcttca ggttcttatg gaatggttgc
    10441 gggtcaaatc ttagatatgg ctggtgaagg aaaagagttg acattagctg aaattgagca
    10501 gattcatcgc ttgaaaactg ggcgactttt aacttttcct ttcgtagctg ctggaattgt
    10561 tgctcaaaaa tcaacggatg aagttgaaaa acttcgtcaa gtggggcaaa ttttgggatt
    10621 ggcttttcaa attcgagacg atattttaga tgttacagca acttttgctg agcttggaaa
    10681 aacaccaggt aaggatattt tagaggaaaa atcaacatat gttgctcatt taggacttga
    10741 gggagcaaaa aaatcactga cggaaaactt gtcagaggtt aaaaaattac tgacagactt
    10801 atcagttact gacagctctg aaatttttaa aattattgaa caattggaag tgaaataaat
    10861 ggattttcaa atcaaaattt tgacagaaaa tgatagaact atcattgaaa aattttttga
    10921 aaaagcgagt gattatgcaa ttcttgagag cggtttttca aatccacaac tagagacgga
    10981 aagtttcata aatgatttac cacctgcaaa aaagctgact gacaaattca atcatggtat
    11041 ttttgataaa aataataact tagtcggtgt gattgattta ataaaggatt ttccaacaaa
    11101 aggggaattt atgctagggt tacttgaatt tgtacctgct gtccgtcacc aaggtttagg
    11161 taaagctgtt cataaaattt tgattgagaa agttcgtgat ttaggagcaa agagtttacg
    11221 aatcggtgtt ttagaagtca ataattctgc tataaaattt tggaaatcct taggatatat
    11281 aaaattcaaa gaaatagaac aagattttgg aaataaaaag caaaagattg ccgtgatgag
    11341 attgaagtta taatttaaaa aaatgaaata aaaaaagaaa ttattagtta catttctaag
    11401 aaaaatacgt ataattacta taaagaaaga tctacatgaa agaaagaatt gacgtacttg
    11461 ccacgaatca aggtttgttt gaaacacgag agcaggccaa aagaggagta atggctggtc
    11521 tagttgttga tagcaaatca ggagaacgtt acgataaacc tggtcagaaa attgatgatg
    11581 gaacagaact tcgtcttaaa ggtgaaaagt taagatatgt tagtcgagga ggattaaaat
    11641 tagaaaaggc gcttaaagaa ttccatttag aaattaatgg aaaaacttgt cttgatattg
    11701 gttcttcaac tggtggtttt actgatgtaa tgcttcaaaa tggagccaaa ttagtctatg
    11761 ctttagatgt tggaaccaat caattggctt ggaaaattcg ctcagatgaa cgcgttgtcg
    11821 ttatggaaca atttaatttc cgaaatgctg ttttagctga ctttggacaa ggaagaccgt
    11881 catttactag tatagatgtt agttttattt ctttagattt aattctaccg ccactttatg
    11941 aaattttgga agaaaatggc gaagtagcag cacttattaa accgcagttt gaagcgggac
    12001 gtgaacaagt cggaaaaaat ggaattattc gtgattctaa agttcaccaa atgactattg
    12061 aaaaagtttt aaaaacagcc actcaacttg gtttttcagt aaaaggtttg accttttcgc
    12121 caatcaaggg tggggctgga aacgttgaat ttcttgtcca tttacttaaa gatggaaaag
    12181 cagaaattgc tcagcaggtt aatattgaat cagttttaca aaaagaaagt gaagaactat
    12241 gaaaagagaa gaccgattaa actttattgc tcaatttatc cgtgaaaacg aaattaaaac
    12301 gcaagaagaa cttgtgaata ccctcttaac tcatggaatt gacgttactc aagcgaccgt
    12361 ttcccgcgat attaaatcac ttgccctaat caaggtgcca gctgaatctg gtggttatcg
    12421 ttatgattta ccaaaaaaca aggaagtttt acagtcaagc cttcataaag ccttagcttt
    12481 tgatgcaatt acgggaacaa aaatcaaaga taatatgctc tggattcttg ctaatccagg
    12541 gacaacgagt cttgtgaaaa attatctttt ggaagaatat ggcgatgata ttttttcaat
    12601 cattattgat gataatagtg ctttagttat ttttgaaatg gaagaagatg ctaaaaatct
    12661 ttataattta ctgacagaat tttaaattta ctgacaagaa tattgtgata aaattctgct
    12721 gaatattttg agcgaattaa tagctgtcag taaaaaagaa tcaaagtagg aaaaagataa
    12781 ggttattagt ttactaatag ccttgtcatt tatttttgag aaaggaaatt ttgatgttac
    12841 aagagatttc aatcaaaaat tttgcaatta ttgaagaaat tcatctatcc tttgagagtg
    12901 gaatgacgat tttaactggg gaaactggtg cgggaaaatc aataattatt gatgcaatgt
    12961 ctttattatt aggtgggcgt gcttcgagtg attttgtgcg gcatggggca accaaagccg
    13021 aaatagaagg tctctttttc tttgataaaa ctccagaatt gaaggcggta ctattagaac
    13081 ttggctttga agaagtagat tctgaaatta ttttaagacg tgaaattttt gccaatggtc
    13141 gctccgtttg tcgaatcaat ggtcaaatgg ttaatttagc tacgctaaga caagtgggtg
    13201 aattattagt tgatattcat ggtcaacacg atagccaaga attgatgaat ccgaaaagcc
    13261 atcttcgttt acttgatgaa tttggtgatg aagcctttga tgcgataaaa gataattaca
    13321 aactcaaatt tgaaaacttc aaaaatttgc gtcaacagct caatttacga caaaaaaatg
    13381 agcaagaatt tgctcaaaga attgaaatcc ttcaatttca ggctgaagaa attgaagcgg
    13441 cggaaattaa tcttgaagaa gatgaacaat tagttaatcg ccgagaaaag ttaaataata
    13501 ttaaaaatat tgctgattcg cttagtagtg cctatctagc gcttgatgat gaagataatg
    13561 attattcaag tcttaataat atccgaacca caatgacaga actggataaa attagtaact
    13621 ttgataatga ctatcaagaa cttgctgaca agaccgctga aagctattat gtattagaag
    13681 aagttgctaa tcaaattcaa agaatcatga gtgatttaga atttaatcca gcggaacttt
    13741 tacaaattga agaccggatt atgaccttga ctactttgaa gaaaaaatat ggcccagaac
    13801 tgtccgatgt gatgaactat ttagagaaag tccaacttga actctcagaa ctgacgggtt
    13861 cagaaaagga ctcagaaaat ctagaaaatt cagttaaagt tgcacaagtt caactcattg
    13921 aagcaagtaa aaaacttaat gaagcgcgcc ataaaattgc aaaagaagtt gaaaaagata
    13981 ttaaacacga actttctgag ctttatatgg aaaaagctga tttcaaagtt agttttgaag
    14041 gggcaaagtt ttcggcaaat ggaaatgagc atgttgaatt ctttattcaa accaatccgg
    14101 gagaaggatt taaaccactg gcaaaaacgg cttcgggtgg tgaactttca cgtttaatgc
    14161 tcgctataaa atcaagcttt tcaagacgcg aaaataaaac agccattgtt tttgacgagg
    14221 ttgacactgg tgtttctggc cgtgttgctc aagcgattgc taataaaata tataaaattg
    14281 cgagacatgg gcaagttctt gcaatttctc atcttccaca agttgtggcc attgccgaca
    14341 gacaatttta tattgaaaaa gcttcaaccg atgacattac tacttccaca gttagaaaat
    14401 taaactttga cgaacgagtt aatgaaattg cgaaaatgct tgctggtgaa gatttaacta
    14461 aagaagcttt ggctcaggct aaacgtttat tgagcaaata aatcgaatat tattaagaaa
    14521 aagtcttgat ttttaatcag gactttttat ctttttgatg tcaaaatcat aatcagtgta
    14581 aaattgtaac cacaaatatg tatataacga aataatcaat gttaaaatta aattgtagtt
    14641 acactattaa aaatattgga gtatatgtga aagtaaataa aatttgaatt ttaatcaatt
    14701 tggcctgttt tttttttttt ttatttatga gcattataat caaaattatt ttttcttgtt
    14761 cgtaggtatt gttggtgcct gtgcgggaat aatctgtatg ttatgcgaaa tgctgatcca
    14821 aattcttaga aatcaaaaga taaaaaataa attaaaaaaa ctaagtatag ataaatttct
    14881 ttgatttgtt agcaaatgtt actgacaagc cttttgaaaa aggctaaaat atctttatat
    14941 actatgtgcc aacttccaag tcagagagcc atagataaaa acgccttctc ctatataaga
    15001 taagggtgtt tttattataa atttgaagcc tcaatttatt ggggcttttt atctccaaag
    15061 gaaatattat gaagtaaaat tagatttttt accattaaga acttctgtta aagttctttt
    15121 atgaattaaa ctcaatatgt tataatgaga tatcaaccat agtactgaaa ggagaggttt
    15181 gtaatttaaa aactgaagtc gtattttata atttaggagt taaaaatgag taaaacacgt
    15241 ttagaagcat ttacggatgc tgtcatcgca attatcatga ctgtcttagt tttagaattg
    15301 gtccgtccag attcagatag cttacaaagt tttattgctt tacttccgca tctgggtgtc
    15361 tattttgtaa gtttttttat acttgctatt tactgggtca atcaccatca tctttttcaa
    15421 agcatcaaaa gaattaatgg aaaagttcta tggataaata ttagttttct ttttgtctta
    15481 tcacttattc ctattttttc taactgggta tcaatctatc ctaattcatt tatcccagaa
    15541 ttaggctatg tgattatctt tttcttaggg aattttattt atctactttt gacaagagag
    15601 ttattgaaaa tcaatggaca tcgtaaaacg tctgagacaa cgattagaaa aaatatccta
    15661 agtgttgtgc tcaatattgt cagcatttta ttaggttatt ttatagctcc agtaatcatg
    15721 cttgttggtt cagccttaat tttttcaatg tgggtaattc cagataaaaa tattgaaaaa
    15781 atgtttaaat aatcttttaa taaaaatatg agtttactta ataaaaaagt ttggaataaa
    15841 taactgacct tctgtcagta aataatatta taagtaaaga ggaataacaa tgattaaagc
    15901 atacatcaaa tattggaaaa aagcaggaga tttaaaatct tattcaaatc gttcggatta
    15961 ttggtgggtt ttcttgacta attcaatcat atttgcgatt ctcagcattt taaactttat
    16021 ggtgacaatc cccaaagctg gaaaaataat gagccaatct gcaactttat cacaaaaaga
    16081 aattattcaa caggtgacag acttatatgc caaccccacg ggtggagcat tagtaatagt
    16141 tattgttaca gctctcattg gtctagctat tcttgttcct gatatcagtt tgacagctcg
    16201 tcgtttacgt gatgctaggt ttccttggtg gattgctctt atttttggag tagctgcaat
    16261 ttatgggctg gttacaatgt ttattcatca agattttcta gcaaaaatgg gttattttgt
    16321 tggatttatc aatttcatta tttatattct ttgtcttttt ccaactaaat atggcattga
    16381 cgaagaagat gattcaagga cttatgaata atcataaaaa tagagaggaa aaatatggtt
    16441 caagcttata aaaaattttg gctaggagct tttactttca atagaaaaac tagtcgtaaa
    16501 gatttttggt cagccttatt aactcatatc ataatatttg ttatcttgtt taaagcttat
    16561 cattttttta atttattaga tttttatcaa ctaacgactt tatggcaaac ttttgcttca
    16621 ttctttcaat tggtatttaa cctatatttc tttggaagtt tattgtcctt cattgctcta
    16681 actgttcgaa gattaaatga tgctgattta ccttgggcac ttatttttct taattttatc
    16741 cttgggctag gaactcttgt gctcttggta cttaacctac ttccaagttc acctagggct
    16801 ttaaaattcg aggaatacaa gattaattct tctcaagaat ttaataattt accagagaca
    16861 aaaacattgt caggcatatt caaggactat ttcaaaaatt actttgaatt tcgcggaaga
    16921 acgacaagaa gaaatttttg gtggatgcaa ctgttttggg gattgacctt tattcttttt
    16981 ctgtttttaa tttatctttt caatcaattt gaacaaataa tgtttggcta caattttatt
    17041 ggtagtatag tactgcgttt attctttttc ctatttatct taggaacatt tttcccacaa
    17101 cttacgattc atgtaagacg cttaagagat gctggtctaa gtaatttagg actatcactt
    17161 ttgttaggtg gaacaagtgg aatattaatt ttctatcaaa tgttcacaaa ggctttaaaa
    17221 ataacatata taaccggtca ctatcaatta gttcaatacc tcttattttt actagtaatg
    17281 attgcagtat tgagtttaat tcttgtagaa gtaatggcga caggagaatt aaaaacaaat
    17341 aaaaaaaatt ctttatttga aaaaatagac tgattaattt cagtctattt ttagtattaa
    17401 ttgttaaact ataaaaagtc acgtttacac aacttgtaaa ttgaattgac atcaaagaag
    17461 tcagtaatag atacaaatgc agttcatgta agccttttta ttaaaaaaat ctttacataa
    17521 tcatgtaaac tactacaaaa atagaaaaaa agtgatataa taaactgtaa gtatacaagg
    17581 aggacggcgc tcttgccaaa aacaatagca tttaagcatg atacagtctt actacatgaa
    17641 accgtagata tgcttgaagt aaagccaaat ggaatttatg ttgatgcgac actaggtggc
    17701 gcaggacata gtgagtatct tcttagtaaa ctgactgatg gtcatcttta ttcatttgac
    17761 caggatgaaa ctgctcatga aaacgcaaaa gtacgcttaa gtgagcaact tgcagaagat
    17821 aaagtaacat tgattaaaag taattttcgc tatcttaaat cagctttagc tgaagtagga
    17881 gtcacgaaaa ttgatggaat tctttatgat ttaggagttt ctagcccaca attcgatgat
    17941 agtcaacgtg gtttctctta caaaaaagag gcaagattag acatgcggat ggaccaaaat
    18001 caaactcttt ctgcttatga agttgtaaat gattatcctt acgaagcatt agttcgcatt
    18061 tttttccgct acggcgaaga taaattctct aaacaaattg ctcgtaagat tgaacaagca
    18121 agaaaaatta aacctattga gacaacaatt gagcttgcgg atttaataaa atctgcatta
    18181 cctcaaaagg agctcaagaa aaaagggcat ccagccaaac gcattttcca agcgattcgt
    18241 attgaagtaa atgatgaact tggagcagcg gaagaatcaa tcgaacaagc cattgattta
    18301 ttaaaagttg atggtcgaat ttcggtaatt acttttcatt ctttggaaga tcgtttaaca
    18361 aaaacaattt tcaaagaata tagtacagtt aatgttccta agggattacc gatgcttcct
    18421 aaagatatgg aagctaaact aaaattggtt aatcgcaaac cagttcttgc aagcgaagaa
    18481 gaactcgaat ttaataatcg agctcatagt gcaaaattaa gagtagcgca aaaacaaaga
    18541 gattaatcaa ataacaagtt ggtctaataa agagggtttt cccacttgag gattgttttt
    18601 ggatgtctta tataaatgaa ataacaatat ttagcttttc tcttttctct tttcaatagt
    18661 gaagagagta agttaaattt ctttagtaag ataaacgagt ggaggcaaag atggcagcac
    18721 agcctaaaga atacttcgat atagaaactg cggcgaaaaa agatagttat ctcattgata
    18781 cggaaacttt agcgccagaa gttctagcaa gtaagtttaa aaagttttct ggtgttgaga
    18841 aggtattcta tctgacaatg gtagttgctg ctttagtgtt ggctgttggt ctactttatg
    18901 ttaagactaa gacacttgaa gttcaaggga atacaatgga cttacgttca aaaatttctc
    18961 aagaaacaac acgaaaaact gaatatgatc aacaaatttt agatttaaca tcaggtacta
    19021 aagtgcttga tacggcgaat aaagctgatt taaaacaaaa tccttctaat gtattgaaag
    19081 caacgaaatg ataaaatttt taaaaaaact aattttcttt ccttttagaa aagtatcacg
    19141 aaatgcccga aaaacgaatt ggagtacaga aagaaatcgt aaacgagtag gtaagagcct
    19201 gtttttccta gctattgcgc tgtttacggt ttttatattt cgttttgtct ggctaattac
    19261 cgtcaatcat gtcggtggaa ccaatcttac aacaatggcc aagaataact accaaagcac
    19321 agtaacggtt caggcgaagc gtgggacaat atatgaccgt acaggtgcgg ctattgcggt
    19381 agactcaagt acctatacaa tttatgctgt aattgataaa acacaggttg attcgaacgg
    19441 aaatcctctt tatattgata agaaagattt taccaaagtt ggagatttct tgaatagtaa
    19501 acttggaatt gaccgtgatt tgattaaaaa gcagctcaat tctaaattga aacaagttca
    19561 atttggccct aaagggagtg atatctctct tgaaaaaatg aaagagattc aaaaagcagc
    19621 tgagaatgaa aaaattgttg gacttggttt cacggcaaat atttctcgtt catatccttt
    19681 tggaaatttt gcttctcaat ttattggtat tgctcgtcct aaagatgaaa atggtactca
    19741 agctctcaag ggtgatatgg gcttggaaaa agcctttaat aatgttttga gtggtgaaaa
    19801 tggtaaagaa acatatcaaa aagatatcta tggtcgccca attccaggaa caactaaagt
    19861 cattgaacct gttaaaaatg gtcaagacgt ttatactaca cttgatgcac aacttcaaag
    19921 aaatcttgaa ggatatatgg acaaagcggc tacggatact ggagcacaac aactttcagg
    19981 aactttagtt gatgctcata ccggtgagat tttagcaaca agtcaacgtc caacctatac
    20041 ggcaacaacg atcaatgacg ctgagaaaca aaagtatttc acttggaaca gtttgctctc
    20101 acaatcagcc tttgaaccgg gttcaacatt taaaactttc ttgatggctg gagcgcttga
    20161 tagtggaaaa gtaaatctta atgaaactta ccaacggaaa cttcaagttt atgatacaac
    20221 gattaatgac tgggatgtaa cagaaaataa aagttatact ttgccagaaa cagtaaccta
    20281 tgctcaaggt tttgctttat cttcaaatat tggaatgagt aaaattgaaa tgaacatggg
    20341 taatgattta tggggaagtt atcttaataa atttaaattt ggtcttaaag taagagccgg
    20401 tttagatggt gaaaatccag gagcccttcc ttcatcgaat gccgttacgc aaattcaatc
    20461 ttcatttggt caaggggttg cggttactcc acttcaattg attagaggtt ggacggctat
    20521 tgctggaaat ggaacaatgc ttgaaccaca tattgtcagc aaagtagtag atccgaatac
    20581 aaaaacaagt ttgacttcta aagcagaagt tattggacat ccggtctcta atgatgcagc
    20641 aagtggtgtg cgtgatttga tgttaacagt aaatactgac cctgtttacg gaacatctta
    20701 ttcaacaagt ggcgattctg agcaaaatct tgctgctggt cctttattta tggttaatgg
    20761 tgaaccggct gcggttaaaa cggggacggc ccaaattgcc tcaacaacgg gtggttatat
    20821 gacaggttct caagattacc tttactctgc tgttgtga
//
