LOCUS       NZ_CP066300            22391 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Lactococcus lactis strain WiKim0098 chromosome.
ACCESSION   NZ_CP066300
VERSION     NZ_CP066300.1
KEYWORDS    RefSeq.
SOURCE      Lactococcus lactis
  ORGANISM  Lactococcus lactis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 2424276)
  AUTHORS   Kim,T.W.
  TITLE     Genomic analysis of Lactococcus lactis WiKim0098
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2424276)
  AUTHORS   Kim,T.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-NOV-2020) Microbiology and Functionality Research
            Group, World Institute of Kimchi, 86, Kimchi-ro, Nam-gu, Gwangju,
            Gwangju, Gwangju 61755, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FLYE v. 2.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 342.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 08:40:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,477
            CDSs (total)                      :: 2,390
            Genes (coding)                    :: 2,331
            CDSs (with protein)               :: 2,331
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 36 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 12 of 59
            Pseudo Genes (multiple problems)  :: 10 of 59
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:11:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 33451
            Orig. end                         :: 55842
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP066300.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22391
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     cand_cluster    1..22391
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22391
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12391](+)"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12391
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(588..602)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.7"
                     /tool="antismash"
     ncRNA           835..1027
                     /db_xref="RFAM:RF00013"
                     /gene="ssrS"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /locus_tag="LacL0098_RS00175"
                     /ncRNA_class="other"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="LacL0098_00175"
                     /product="6S RNA"
     gene            835..1027
                     /gene="ssrS"
                     /locus_tag="LacL0098_RS00175"
                     /old_locus_tag="LacL0098_00175"
     misc_feature    849..863
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.52"
                     /tool="antismash"
     gene            1344..1793
                     /locus_tag="LacL0098_RS00180"
                     /old_locus_tag="LacL0098_00180"
     CDS             1344..1793
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017863945.1"
                     /locus_tag="LacL0098_RS00180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00180"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_038598333.1"
                     /transl_table=11
                     /translation="MLIRNYESKDLNEVINLFKNTIFEVNISDYTLEQIKAWVDVDTKL
                     FDDNLAKTYARVISNHEQIVGFGNIDDKGYIDLFYVSADYQRQGVGQKLLNDLEKSSNY
                     TSFMVNSSITAKPFFEKMGYKETKKNCVHLRGQNFVNFTLKKVVE"
     gene            complement(2002..3624)
                     /locus_tag="LacL0098_RS00185"
                     /old_locus_tag="LacL0098_00185"
     CDS             complement(2002..3624)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012896920.1"
                     /locus_tag="LacL0098_RS00185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00185"
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_098393039.1"
                     /transl_table=11
                     /translation="MIKQFLGIINSEFKDYNRRKFLQDLMAGITVAAVALPLALAFGVS
                     SGTTAAAGLITAIVAGLIISSLSGAFYQISGPTGAMAAILISLIGKYGMNGIFIATFMA
                     GIFLLIAGIFRLGNLISLIPSPVITGFTSGIAIIIASGQIKNFFGIEHFTGSFFDLIKF
                     ISGLHIDYPSTIIGLLTILLMIFYPKSWGKKFPASLLAILLSTLAVLVLKLDIPLVGKI
                     PTTLIPQAHLRLTELNLQDMKTLLIPAISITVLGMTESLLCGASAGRATNHPMDNNQEL
                     VAQGIGNIFIPFFGGIPATAAIARTSVAIKAGAQTRLTGIIHALILLLSMFLFAPFMTH
                     IPLSALAGVLIMTAVRMNEWEAIRFLFKNKLKSGIIEFFVTMIITVIFDLSTAILAGII
                     VGFLLFIVKISQIEINSSQIEPERISQNHHEVFTDWTVIYISGPLFFLNSSKLKQAIDE
                     LPANTNVVLSLRGVPMIDVTSIKLLIDIYSIFHKEERQIVFASMNPKLKESFKRTGLIS
                     MVGEEAIYASVNEFLLDLVDKNK"
     gene            3834..4355
                     /locus_tag="LacL0098_RS00190"
                     /old_locus_tag="LacL0098_00190"
     CDS             3834..4355
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012896921.1"
                     /locus_tag="LacL0098_RS00190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00190"
                     /product="N-acetyltransferase"
                     /protein_id="WP_038598337.1"
                     /transl_table=11
                     /translation="MIIKTINLEDYKEVAELIRESFGHSEHGYGNEAELVDKIRNEEGY
                     IKDLEIVAFEDGKIVGHGLLSEVEIVSDSQKFKGLVLAPLDVLTTYQGKGIGAAVLLEL
                     EKRAKILDYPFISILGHETYYPKFGYVPASQYQIKAPFEVPDENFMIKELTDGGLEGKS
                     GVIHYSEAFN"
     tRNA            4597..4669
                     /anticodon=(pos:38081..38083,aa:Lys,seq:ctt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LacL0098_RS00195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="LacL0098_00195"
                     /product="tRNA-Lys"
     gene            4597..4669
                     /locus_tag="LacL0098_RS00195"
                     /old_locus_tag="LacL0098_00195"
     gene            4821..5996
                     /locus_tag="LacL0098_RS00200"
                     /old_locus_tag="LacL0098_00200"
     CDS             4821..5996
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (30-381). E-value:
                     7.8e-65. Score: 211.3. Matches aSDomain:
                     nrpspksdomains_LacL0098_RS00200_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081831.1"
                     /locus_tag="LacL0098_RS00200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00200"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_098393041.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.9e-63, bitscore:
                     211.3, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.4e-06,
                     bitscore: 23.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLKKFNPNLDKIEISLIRQFDQQVSSIPDIIKLTLGEPDFYTP
                     EHVKQAGIAAIENNQSHYTGMAGLLELRQAASEFMNKKYGLSYAAEDEILVTVGVTEAI
                     SSVLLSILVAGDEVLIPAPAYPGYEPLITLAGGSLVEIDTRANDFVLTPEMLEQAIVER
                     EGKVKAVILNYPANPTGVTYNREQIKALAEVLKKHEVFVIADEVYSELNYTDQPHVSIA
                     EYAPEQTIVLNGLSKSHAMTGWRIGLIFAARELVAQIIKTHQYLVTSASTQSQFAAIEA
                     LKNGADDALPMKKEYLKRRDYIIEKMSDLGFKIIEPDGAFYIFAKIPADLEQDSFKFAV
                     DFAKENAVAIIPGIAFGQYGEGFVRLSYAASMDMIEQAMARLTDYVTKKRG"
     aSDomain        4911..5963
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LacL0098_RS00200_Aminotran_1_2.1
                     "
                     /evalue="7.80E-65"
                     /label="LacL0098_RS00200_Aminotran_1_2.1"
                     /locus_tag="LacL0098_RS00200"
                     /protein_end="381"
                     /protein_start="30"
                     /score="211.3"
                     /tool="antismash"
                     /translation="DIIKLTLGEPDFYTPEHVKQAGIAAIENNQSHYTGMAGLLELRQA
                     ASEFMNKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLIPAPAYPGYEPLITL
                     AGGSLVEIDTRANDFVLTPEMLEQAIVEREGKVKAVILNYPANPTGVTYNREQIKALAE
                     VLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNGLSKSHAMTGWRIGLIFAA
                     RELVAQIIKTHQYLVTSASTQSQFAAIEALKNGADDALPMKKEYLKRRDYIIEKMSDLG
                     FKIIEPDGAFYIFAKIPADLEQDSFKFAVDFAKENAVAIIPGIAFGQYGEGFVRLSYAA
                     SMDMIEQAMAR"
     misc_feature    complement(6056..6072)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 26.85"
                     /tool="antismash"
     misc_feature    6131..6142
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            6164..7663
                     /locus_tag="LacL0098_RS00205"
                     /old_locus_tag="LacL0098_00205"
     CDS             6164..7663
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023805.4"
                     /locus_tag="LacL0098_RS00205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00205"
                     /product="M57 family metalloprotease"
                     /protein_id="WP_181022864.1"
                     /transl_table=11
                     /translation="MKKNKLFFLLAFLVLLVSGIKAKAETLTGQAHMQNSGWQTSQTVN
                     ENQILNLGIVDTTLRVEAMKISVTGPVSGGISYQAQSQSLGWQPAVSDGQIAGTVGKSL
                     RMETIKVSLTGDLATSYDIYYRTQVENYGWLGWTKDGNPSGTVSKSLRLQALQLVLVKK
                     GSTLPITVDTSKNPCISPDAPLQTYRMISSTNVYNSGTDARNYQYFAIKESNRSDGLYS
                     APYATDNTADIANQKAKNYDKTVVYADKAVVLSNGSNFTHINLNGSWYWVDSDALSWEQ
                     VLPYASHPILTYNSYNSNGQIVYYSNSKFSTQLDEAANYWNQVLGTTVFVKTTNSLATN
                     MTLKVSDVTNGTTGDSSYLMGAYGNYGLMFVNLSFIGKDQGNFNYTSSSVIKNIFIHEL
                     GHTLGLDHTGDSNSDSNSNLLPGSVGWSWSDKSDIMWATNISGDSSSQTVLTAQDIAAA
                     KLVRNLKMFYSTANPLNYEKIISKDVTNSSSNQFEVLYPRK"
     gene            7670..8923
                     /locus_tag="LacL0098_RS00210"
                     /old_locus_tag="LacL0098_00210"
     CDS             7670..8923
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LacL0098_RS00210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LacL0098_00210"
                     /product="hypothetical protein"
                     /protein_id="WP_098393043.1"
                     /transl_table=11
                     /translation="MNKKEITLLVAVPLVSISILSLKEINVQAQESNTNSQALERPASS
                     IIAMYPIAAPSATTPNNQVSKEDPNPGSSIIAMYPVTLASSATSDSQSSTAPLITDTPD
                     AHNTGDFAEGSTVETNSGEQGTDSSTSPTDTMYPETATPAPTEPDDNTIVHLIDAISGK
                     EVGTVTMGQWLEAFKADYNGVVLPGGYRNANWRSDAQGGPELSRTQSPDYEYPVISTAE
                     YENEINHATVVVHYIDEETNAEVGTWTYLVGGQVGYLPGDYKNLPFFYRVDTNKAEENS
                     KLDNGQISRKVYLLKMQANATPYPVPNSQSSEASSSASQSSSSAASSSISGSLMASSAQ
                     ASTTTSASSSAVTTTSQSSTSNSSKAVSQVSSSATSTAKALPTTADNAKESFTIMLIGL
                     LLSVFSYIFYQMRKRIFK"
     gene            9133..9887
                     /gene="recO"
                     /locus_tag="LacL0098_RS00215"
                     /old_locus_tag="LacL0098_00215"
                     /pseudo=""
     CDS             9133..9887
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015425615.1"
                     /locus_tag="LacL0098_RS00215"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00215"
                     /product="DNA repair protein RecO"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRDAETHGLVLYSRNYKEKDKLVKIFTESFGKRMFFVKNFGKSPY
                     ASSLQAFTDGKLTATINDGGFSFIEDVSEVVVYKNISSDIFINAHASYIISLADAAISD
                     NQYDPGLYGFLKRSLELLDQGFDMEVVTNIFELQVLHRFGVSLNFSECAFCHKTVGPFD
                     FSYKFSGCLCPQHFDEDLRRSHLDPNVIYLVNLFQEISLDELKKISIKADMKLKIRQFI
                     DGLYDEYVGIHLKSKNSWTECLGGQIL"
     gene            10001..10882
                     /locus_tag="LacL0098_RS00220"
                     /old_locus_tag="LacL0098_00220"
     CDS             10001..10882
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132218.1"
                     /locus_tag="LacL0098_RS00220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00220"
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_038598351.1"
                     /sec_met_domain="TIGR01716 (E-value: 7.9e-25, bitscore:
                     84.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSKSWGRVFREIREMKNLSLAKVAGDYENSPNLITSKQQVSRFE
                     LGKSDITLTKIYELVENMGLSFEEYLYHVRNYELPSGRALFEELGRLQELSNLSEIENV
                     YQKLQMRFIESQNRIDYWSALEYKSFLAQKNYKSYQISEEEIQEISDDLFSMLEWGEAE
                     LFLFGELIYFLPETLVFEFSKELIKRTKFYRKIPENKTQVTLVIRDCTNYFIEKSQVEQ
                     AEILLNSYEKLIESPIVDVYSRKEYLFVEGNYQFLIGNIEKGNQIFENLAIMYEKLGYD
                     NAASYMREKRHK"
     gene            11114..12391
                     /locus_tag="LacL0098_RS00225"
                     /old_locus_tag="LacL0098_00225"
     CDS             11114..12391
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132219.1"
                     /locus_tag="LacL0098_RS00225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00225"
                     /product="radical SAM protein"
                     /protein_id="WP_104142650.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.6e-37, bitscore:
                     126.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.2e-10, bitscore: 36.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.4e-15, bitscore: 53.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.6e-10, bitscore:
                     38.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKLNQFVKQVENAENIILYNFYNGKSIKYSKDNFPTTESFIAND
                     DIYELLKSEEFLLENFNFKNPYQELERTLQLILLVHEDCNFRCTYCYEKFEKRAMSLET
                     ANDIIKYINNEVKNNRSKYDKIQLSWFGGEPLLNLKIIEYISSSVIEIARKNKIEYSAD
                     MTTNGYLLNPRVFQKLVNLKVKSFQITVDGGQKYHDKQRILKNGHGTYERIISNLLLIQ
                     EMIPSDIFIVLRTNVGEENYKFMEEYIHESIINFGKCENILFAFHNIGNWGERNSKIIE
                     KDVRFELASKVIEQGGRTVPFIWSMTASNLCYASIKNHYVIGSDGLVYKCTVALYQANN
                     ILGRIGKGGKLLISENKESLWVNSTETEECKSCSVLPICMNNRCPLKRLNADSLQYCIS
                     SKDKTSDMILMLEKQNLITYEIGIEV"
     gene            12395..13957
                     /locus_tag="LacL0098_RS00230"
                     /old_locus_tag="LacL0098_00230"
     CDS             12395..13957
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="LacL0098_RS00230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00230"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_038598358.1"
                     /transl_table=11
                     /translation="MLTYIKKNKFQNIILLLIIITNMALYVYGNYLKVNLVNALMKSNI
                     SKGLFWFLLSLIIFLIMMIIRKIEVVQTEKTTQTQLNLIRKDILKNLTSLTYQEFSKES
                     KDQYNSWLNNDAILLDTDGYKEIYFMIENIFLVLFSSFALFTFHWILFATTLGLALILL
                     ILPKLFQKKMVKATQEVSNSAEKALKESNDKLKGYEVIYHNQQFDFLTSRLLQVYEQLK
                     AVKISKAKLVSTAMMCTVGLSFLSQSVILGVNALLAFQHIVLLGTLLVSGNFAGNIFNG
                     LNTIADCFTIALGTDKLLTKYPKVSNQRESKSVSTFEKKLSFENVSIKLGDKKITYPNF
                     EIKKGKKYAIVGESGSGKTTLIQLLNGDLEDYQGTIKLDGLDYKIIDKGKLQSIIATIS
                     QFPYLFNDSLEENLKMNREITDEKLEKVLKEVKAEDFLKGKLTNKFDNNLSGGQQQRVA
                     IARELLGEKPILIMDESTASLDKLTALAVEQNILQNPSLTVIMITHHFYDETRPYFDEV
                     IEL"
     gene            complement(14039..15457)
                     /gene="lpdA"
                     /locus_tag="LacL0098_RS00235"
                     /old_locus_tag="LacL0098_00235"
     CDS             complement(14039..15457)
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132223.1"
                     /locus_tag="LacL0098_RS00235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00235"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_010905074.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.4e-70, bitscore:
                     232.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVGAQATEVDLVVIGSGPGGYVAAIRAAELGKKVTIIEKDNVGG
                     VCLNIGCIPSKALINIGHHYQESLEEEKGENPFGLSVGNVKLNWESAQKWKQDKVVNQL
                     TGGVKMLLKKHKVDVIQGTAEFIDNNTINVEQEDGFQLLQFNDVIISTGSRPIEIPSFP
                     FGGRIIDSTGALSLPEVPKHLIIVGGGVIGSELGGAYRMLGSKITIVEGLDHILNGFDK
                     EMSDIIANRVKSAGSEIFTSAMAKSATQTDKDVTLTFEVDGKEQTVTGDYLLVSVGRRP
                     NTDLIGLNNTDVKLTDRGLIEVDDSYATNVPHIYAIGDVVPGPMLAHKASFQAKVAAAA
                     IAGAEDDVDLHVALPAVAYTTTELATVGETPESVKDRKDVKISKFPFAANGRAISMNDT
                     TGFLRLITETKEGALIGAQIVGPGASDLISGLSLAIENGLTSKDISLTIQPHPTLGEAI
                     MDTAELADGLPIHV"
     gene            complement(15651..17258)
                     /locus_tag="LacL0098_RS00240"
                     /old_locus_tag="LacL0098_00240"
     CDS             complement(15651..17258)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017863950.1"
                     /locus_tag="LacL0098_RS00240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00240"
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="WP_200984804.1"
                     /transl_table=11
                     /translation="MTEIFKMPDIGEGMHEGDIANWLVKVGDVVKEDDPIAEVQNDKLM
                     QEILSPYSGTVTKLFVEAGTTVEVDSPLVEFDGDGSGSSAAAPAPQETASSDTATTDAP
                     SGESQIFTMPDIGEGMHEGDIANWLVKVGDEIKEDDPVAEVQNDKLMQEILSPYSGKVT
                     KLFVEAGTTVEVGAPLIEYNGNGAAPAAASPAPVAEAPKAASPASPASPANAPLTKTTS
                     TGHILAMPSVRHYARKAGIDLSQVPATGRHGHTTLADVKAFESGNVAPIAQTAPEAAPA
                     PKADKPAAPVAEKAPSVKAGTGDRREAMNPTRKVVSKVMTAQHTHIPPVTNFDQVEVSK
                     LVKHRAVFKEIAAKQDIKLTYLAYVAKALATTAHKFPDINASVDYEKQEIVYHEHVNLG
                     IAVNAPTGLYVPVIHEAETKSILEIAKEIAELATATREGTLKPQQMQGSTITISNIGSA
                     RGSWFTPIINGSDVVILGLGSIVKEPIVNGEGEIVVGQNMKLSMTYDHRLIDGMLGQTS
                     LNYLKSLLADPEFMLMEI"
     gene            complement(17251..18231)
                     /locus_tag="LacL0098_RS00245"
                     /old_locus_tag="LacL0098_00245"
     CDS             complement(17251..18231)
                     /EC_number="1.2.4.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019336188.1"
                     /locus_tag="LacL0098_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00245"
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="WP_003132227.1"
                     /transl_table=11
                     /translation="MAVKTYIAAITEALDLALEKDKDALIFGEDVGQNGGVFRATDGLQ
                     AKYGEERVFNTPLAESGIGGMAIGLATQGFHPIMEIQFGTFIFEVFDSIAGQMSRTRYR
                     FNNTRSNNIVVRTPYGIGTKTPEMHADSIEGLFSQIPGIRVVMPSNPADAKGLLLASIE
                     NNDPVIFLENLHLYRSLKGEVPEGYYTTPLDTAAVAKEGSDVSIIAYGGTVPLALKAAE
                     QLEKDGIKAEVLDLRTVAPLDIASIGKTVEKTGRVVVVQEAQRTAGIAANVMAEISERF
                     VLNLKAPIGRVSGPDSIFPFAQAENDWAVKAEDIVNKVKEVVDYD"
     gene            complement(18234..19358)
                     /locus_tag="LacL0098_RS00250"
                     /old_locus_tag="LacL0098_00250"
     CDS             complement(18234..19358)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019299785.1"
                     /locus_tag="LacL0098_RS00250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00250"
                     /product="thiamine pyrophosphate-dependent dehydrogenase E1
                     component subunit alpha"
                     /protein_id="WP_195362641.1"
                     /transl_table=11
                     /translation="MSNSEQILDFKAQLELQDTTFPMLQILNEEGKIVDEEGLKRAGLS
                     DEKLVELFKSMLFARQVDIRSMKLAKQGRMGFFGPHAGQEASQMASSFAFSDEDWLFPG
                     YRDLPQIYAKGWPIWKGLLWSRGHQLGNEYTTDDGKPVNSWFPQIIIGAQYVEAAGVAL
                     GLKKRKKDAVAFVYTGDGGSSQGDTYEGINFAGAYKAPLVAFIQNNGYAISTPRSLQSA
                     APHLAAKGWAAGAPSIVVDGMDAIAMYLASKEARAWAVAGNGPVVIEAITNRLEPHSTA
                     GDDPLRYRTKEDIEAWWKKEPLVRMRNFLTEKGLWDTEKEEAYIAELDAGIDADIKKAN
                     NVEKQKISSFIKNTLEVPSQAMAEQIAKFESEGK"
     gene            complement(19447..20448)
                     /locus_tag="LacL0098_RS00255"
                     /old_locus_tag="LacL0098_00255"
     CDS             complement(19447..20448)
                     /EC_number="6.3.1.20"
                     /GO_function="GO:0017118 - lipoyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017863951.1"
                     /locus_tag="LacL0098_RS00255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00255"
                     /product="lipoate--protein ligase"
                     /protein_id="WP_104142660.1"
                     /transl_table=11
                     /translation="MQYINYLGQDAYTNIAMDSWLLYHLKPTEPVFALWQNKRAVIVGR
                     NQNTFAEVNQDYIDSHDVQVVRRVSGGGAVYHDEGNICFTFFVPVENSGSVNFKKFVQP
                     MYEALHAVGIKAEITGRNDLEVEGKKISGNAQRYAGGYLMHHGTLLWDTDVEAMIRSLN
                     VSDEKFVSKAAKSVRARVGNIKDFAPEDLTLDSFIDALKYYLTDEGKDGELVLTDDQLS
                     SIKKIRDEQFATWDWNYGESPKFSFQNHAKFTGGAIDIQVNVENGKITEINFQGDFLGV
                     RDWRDIKEQFIGLEFEPSAILEVLETNKEGQYFGTIQNTELSEMFKADYRTD"
     misc_feature    complement(20444..20457)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.49"
                     /tool="antismash"
     gene            complement(20648..21493)
                     /locus_tag="LacL0098_RS00260"
                     /old_locus_tag="LacL0098_00260"
     CDS             complement(20648..21493)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132231.1"
                     /locus_tag="LacL0098_RS00260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00260"
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="WP_104142663.1"
                     /transl_table=11
                     /translation="MSGFTKIVFKLHNFLDRNKIKNNLKFKPSLTSKTLVFAHRGSKSN
                     CPENTLAAFHEAVRVHADGIELDVHLSLDNELIVIHDEKIDRTTNGKGLVKNMNAIDLK
                     KFDAGSWFNSKFTDEKIPTLSEVLKILTDLSFTGYLNIEIKTDKFDYPGIEKKLSDLMT
                     ETKWPFSYIYSSFNFDSLKKIHTFDSKAEVNYLTKNLLTLKSHYKGSSTDFISGIHPRR
                     TYAFKHPLLLKSSKRPLRLWTVNQETEMRQAFQQHVAGIITDFPERALEIRREIQDQSK
                     "
     gene            complement(21573..22223)
                     /locus_tag="LacL0098_RS00265"
                     /old_locus_tag="LacL0098_00265"
     CDS             complement(21573..22223)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015425621.1"
                     /locus_tag="LacL0098_RS00265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LacL0098_00265"
                     /product="HD domain-containing protein"
                     /protein_id="WP_038598376.1"
                     /transl_table=11
                     /translation="MIDLKKIKRFAQEIHDKNNDGHGFDHIERVVALAQKILLTEPSAN
                     QELVLATCYLHDTYDEKLTEDVPKQKAKVAQFLNELKIDKKLIDELFMIIDNMSFSSNL
                     IERKTLSLNGQIVQDADRLDAMGAWGIVRTLEYGWAKNRVFYDPNLPPLDYNSKEDYHS
                     QKNNSTLNHFYEKLFLLKDLLNTTEGKRLGEKRDKIMHLFVSQIEEEYKETLL"
ORIGIN
        1 tctgataaac tttatctttc taaatttatt ggttttccta atgctgcagt tgaccgtatt
       61 gttcctgctc aaaaacataa agatgttctc tatgttgagg tagagccttt tagtgagtgg
      121 gtaatagatg caagtcattt aaaaaataaa gaaatcaaac ttgaaggagt tcattataca
      181 actgacctcg aaccatttat tgagcgtaaa cttttttctg taaactcagg acatgctgca
      241 gttgcctatt ctagcgcata taaaggttat aaaacaatat tagaaggttt acaggatgaa
      301 gaaattttga atatcctaaa agcagttcaa aaagaaacac gcgctttact tttagcaaaa
      361 tgggctcaat attttaagca agatgagtta attaaatatc atgaactaat catttctcgc
      421 ttttctaatc cagaaattat tgatgaagtc tcacgcgtgg caagaacacc tatcaggaaa
      481 ttaggatatg atgaacgttt tattcgtcca ataagagaat taaacgatcg taagctttct
      541 tatcaaaatc atctagatat tgttggaaaa atttttgctt accatgatga aaatgatgct
      601 caagccattc aactccaaga aaaactaaaa ataacagaac tcccaatgct cattgaagaa
      661 gtgactggtc taagcaatca aaagttgatt ttggaaattg aaaaggttat taatcactat
      721 aaaaaataaa atttggtaga gatgatgatt atttattaat acaatttatg actcaaaatt
      781 aaaccgcttt ctattgaaaa aaaagataaa aagtgttatt atagaatcat agaaaaagca
      841 ctggaatgtg cgagctcttt catttttttg accgactata tttgtattgc ataggggttc
      901 atgagacatt cggtagcgta atacctcgaa cgaaagtagg ggaagctgat gcgaagcgag
      961 aacacccacc tggcgtttta gcgggttcaa tacacggaag agcatacggc attcaatcag
     1021 tgttttttgt gtattaaaaa ttaggcaaat caataataaa tctaaggcat gggactatat
     1081 atttaaatag aactgcttta taacattaga tttgtttttg cattcatttg ttaacaattt
     1141 ttgttaattt atttgttgga taatttttgt agaataaaga tacctcaatg tgtaggcctt
     1201 acacgaataa taaaaggtca gtctaacttt gtttgtacct agatatgtac ttcaaactat
     1261 ctttcgattt tgaaagccca tagtttaact cctatgagtt ttttgtttgt aaaaggatat
     1321 gaatctaaaa ggagtaaaga tttatgctga ttagaaatta tgaatcaaaa gatttaaatg
     1381 aagttattaa tctgtttaaa aacactattt ttgaagtaaa tatttctgat tatactttgg
     1441 aacagattaa agcttgggtt gacgttgaca caaagttatt tgatgataat cttgccaaaa
     1501 cctacgccag agtcatttct aatcatgagc agatagtagg atttggtaac attgatgata
     1561 aaggatatat tgatttattt tatgtcagtg cagactatca aaggcaggga gtagggcaaa
     1621 aacttctaaa tgatttagaa aaaagctcga attatacaag ctttatggtt aattcatcta
     1681 ttactgctaa gcccttcttt gaaaaaatgg gctataaaga aacaaaaaag aactgtgtac
     1741 acttgcgagg gcaaaatttt gttaatttta ctttaaaaaa agtcgttgaa taaagttgat
     1801 tttatttaac aacttaaaat aacgtgcagg tactgagcca cgtaaaaagc tgataggctt
     1861 atagtactta caataatact gaagatatta catttattaa tggtggatat tctagataaa
     1921 agctcactta tttgagttct ttctcaaatt tcttttagga gtttataaat aaaaaataga
     1981 ccaatcattg gcctattttt tttatttatt tttatcaact aaatctaaaa ggaattcatt
     2041 gacacttgcg taaatggctt cttcaccaac catgctaata agtccagttc tcttaaatga
     2101 ttcttttaat ttaggattca ttgaggcgaa gacaatttgg cgttcttcct tatgaaaaat
     2161 actgtaaata tcaatcaata gttttataga agtgacgtca atcatcggta cacctcttag
     2221 agaaagaaca acattagtat ttgctggaag ttcatcaatt gcttgtttta acttgctact
     2281 atttaaaaag aagagcgggc cagaaatata aataactgtc caatcagtaa atacttcgtg
     2341 atgattttga ctgattcgtt cgggttcaat ttgtgaacta ttaatctcaa tttgggaaat
     2401 ttttacgata aagagtaaga aaccaacaat gattcctgct aatattgcag tacttaaatc
     2461 gaaaataaca gtgataatca tcgttacaaa aaattcgatg attccacttt ttaatttatt
     2521 tttgaataag aaacgaatgg cttcccactc gttcattctt acggcggtca tgataagaac
     2581 accagcaagg gcacttagtg gaatatgagt cataaatggt gcaaatagaa acattgacag
     2641 gagaagaata agggcgtgaa taataccagt taagcgagtt tgagcacctg cttttatagc
     2701 tacacttgtt cgagcaattg ctgctgttgc tggaattcct ccgaaaaagg gaatgaaaat
     2761 atttccgatt ccttgagcaa cgagttcttg gttattatcc attgggtgat tggttgcacg
     2821 acctgctgag gcaccacaaa ggagactttc ggtcattcca agtacggtga tgcttatggc
     2881 tgggataagt agagttttca tgtcttgaag attcaattca gtcaaacgta gatgagcttg
     2941 gggaataagg gtggttggaa tttttcctac taaaggaata tctagtttta ggacaaggac
     3001 tgctaaagtt gacagcaaga tagccaacaa tgaagctggg aattttttac cccatgattt
     3061 aggatagaaa atcattaata agattgttaa aagtccaata attgttgaag gataatcaat
     3121 gtgtaagcca gagataaatt ttattaaatc aaaaaaagaa cctgtaaaat gttctattcc
     3181 gaaaaagttt ttaatttgtc cactggcaat gatgatggca ataccagaag taaaacctgt
     3241 tattactggt gagggaataa gtgaaattaa atttcctaaa cggaaaatac ctgcgattaa
     3301 tagaaagatt cctgccataa aagtagcaat aaatattcca ttcattccgt atttaccaat
     3361 gagtgaaatt aaaatagccg ccattgctcc tgttggacca gaaatttgat agaaagctcc
     3421 agaaagtgag ctaataatca gacctgcaac aatggctgtt ataagaccgg ctgcggctgt
     3481 tgtaccactt gatacaccga aggcaagggc cagcgggagg gcaacggcag ctacagtaat
     3541 tcccgccatc aaatcttgta agaattttcg tcggttgtag tctttgaatt ctgagttaat
     3601 aatacctaaa aattgtttaa tcataataat tcctttaatt ttttatcaca atattctatg
     3661 ataacagaga tgagtaatca tatcaaataa ttatcggaat cgaaatgaaa tcaagattag
     3721 acaaattttt tgtaattaaa aaactagaaa ataaatttct tactaatatc taatgaaaaa
     3781 tttaagaata actgttaaaa taatgataga gattatatta ggagaggaag ataatgataa
     3841 ttaaaacaat aaatttagaa gactataaag aagttgctga acttattcgt gaatcttttg
     3901 gtcattcaga acatggttat ggtaatgagg ctgaacttgt tgataaaatt cgtaatgaag
     3961 aaggttatat caaagatttg gaaattgttg cttttgaaga tggtaaaatc gttggtcacg
     4021 gtcttttgag tgaggtagag atagtaagtg actcacaaaa attcaaaggt ttggtcttag
     4081 ctccccttga tgttttaact acttaccaag gtaaaggaat tggggcagca gtattattgg
     4141 aacttgaaaa aagagcaaaa attttggatt atccgtttat tagtatttta gggcatgaaa
     4201 cttattatcc taagtttggt tatgtaccag caagtcaata tcaaatcaaa gcaccttttg
     4261 aagttcctga tgagaacttt atgattaaag aattaactga cggtggctta gaaggaaaat
     4321 caggagtaat tcactactca gaagccttta actaagtaac aattgagttt aaaactcttt
     4381 gttagtaact ctatatttaa gacttaaata ataaaaattc ttgcattttg gtctataaat
     4441 cggtataata agctagtaag ttggcccggt agctcagttg gcttgaagca ctgcttcaag
     4501 gttgcggata gaaaaattgc gaagcaattt atcattacta ccacagaatt ttagaattct
     4561 agaagtggtc acaaaatatt caacttttta taagttggcc cggtagctca gttggtagag
     4621 cagtagactc ttaatctatg ggtccagggt tcgagcccct gccgagccat aaatagtaaa
     4681 agcactctaa atttttaaaa gtttagagtg ctttttttac tgacagaaat ctgtcagtaa
     4741 agtaaatagt ctgaaaatag tgtataatat tgtcaaaaga tttctgtcag taaaacagga
     4801 tggtaagtag aggatgtttt atggatttat taaaaaaatt taaccctaat ttagataaaa
     4861 ttgaaatttc attgattcgt cagtttgacc aacaagtttc atctattcct gatattataa
     4921 agttgacttt gggagaacct gatttttata cgcctgagca tgttaaacaa gcagggattg
     4981 cggcgattga aaataatcaa agtcattata ctggaatggc tggtttacta gaactacgtc
     5041 aggcagctag tgaatttatg aataaaaaat atggtttatc ttatgcagca gaagatgaaa
     5101 ttttagttac tgttggagta acggaagcca tttctagtgt tttgttatca attttagttg
     5161 ctggtgatga agttttgatt cccgcgcctg catatcctgg ttatgagcca ttaattacgc
     5221 ttgctggcgg ttctttggtt gaaattgata caagagctaa tgattttgtt ctcacgcctg
     5281 agatgcttga acaagcgatt gtcgagcgtg agggaaaagt taaggctgtt attttgaatt
     5341 atccagcaaa tcctacaggg gtaacttata atcgggagca aattaaggct ttagctgaag
     5401 ttttgaaaaa gcatgaagta tttgtgattg ctgatgaagt ttattctgaa ctaaattata
     5461 ctgaccaacc gcatgtatca attgctgaat atgcacctga gcaaacaatc gttcttaatg
     5521 gtttatcaaa atcgcatgcg atgactggtt ggcggattgg attaatcttt gcggcgcgtg
     5581 aattagtggc acagattatt aagactcacc aatatttggt gacttcggct tcaactcagt
     5641 cacagtttgc agcgattgaa gctttgaaaa atggcgctga tgatgctctt ccgatgaaaa
     5701 aagaatatct taaacgtcgt gattatatta ttgaaaagat gtcagacctt ggtttcaaaa
     5761 ttattgaacc agatggagct ttctacattt ttgcaaaaat tccagctgat ttagaacaag
     5821 attcattcaa atttgctgtg gattttgcaa aagaaaatgc agttgccatt attcctggta
     5881 tcgcttttgg tcagtacggt gaaggatttg tccgcttatc ttatgcggct tcaatggata
     5941 tgattgagca agcaatggca agattgacgg attatgtgac taaaaaacgt ggataagatt
     6001 ttcctaaaaa aactactagt tggagacaac aagtggtttt tttattttac atagattgtt
     6061 ttaaaattac aaaagtaatt aaaagaaaaa atattgacat tttggtagaa aaagagtaag
     6121 ctttgtttaa gaaaacgata acatgccaat ggaggataga gttatgaaga aaaataaatt
     6181 atttttcttg cttgcttttc tagttttgct tgtttcagga attaaagcaa aggctgaaac
     6241 tttaacaggt caagcacata tgcaaaatag tggttggcag acaagtcaaa cagttaatga
     6301 aaatcaaatt ttgaatcttg gaatagttga cacaacattg agagtggaag ctatgaaaat
     6361 ttcggttaca gggcctgttt caggcgggat tagctaccaa gctcaaagcc aaagtcttgg
     6421 ttggcaacca gcggtaagtg atgggcaaat agctggtacg gttggaaagt ccttgcgaat
     6481 ggaaaccatt aaagtttcac taacagggga tttggcaacc agttatgata tttattatcg
     6541 gacgcaagtt gaaaattatg gctggcttgg ctggacaaag gatggaaatc caagcggaac
     6601 ggtgagtaaa tctctgagat tgcaagcctt gcagcttgta cttgtcaaaa aaggttcaac
     6661 attgccaatc acagtcgata caagcaaaaa tccttgtatt agtcctgatg cccccctcca
     6721 gacttatcga atgattagct caacgaatgt ctataattct gggacagatg caagaaatta
     6781 tcaatatttt gcgataaaag aatctaatcg ttctgatggt ttgtactctg ctccctatgc
     6841 gacagataat acagcagata tcgcaaatca aaaagcaaaa aattatgata agacggttgt
     6901 ttatgctgat aaggcagttg tattatctaa cggaagtaac tttacacata ttaatttaaa
     6961 tggaagttgg tattgggtgg atagtgatgc tttgagttgg gaacaggtgc ttccttatgc
     7021 tagtcatcca atcctgacct ataattctta taacagtaat ggacaaattg tttattatag
     7081 taattctaag ttttcaacac aattagatga agcagcaaat tattggaatc aagtcttggg
     7141 aacaacagta tttgtaaaaa caacaaattc tttagcgaca aatatgacat taaaagtgtc
     7201 agatgtaacc aatgggacaa cgggcgactc ttcttatctg atgggagcct atggaaatta
     7261 tggtctaatg tttgtaaatt tatcatttat tggtaaagac caagggaatt ttaattatac
     7321 ttctagttct gtgattaaaa atatatttat ccatgaattg ggacatacat tgggactaga
     7381 ccatactgga gatagcaata gtgattcgaa tagcaattta ttgccaggtt ctgttggctg
     7441 gtcttggtca gataaaagtg atatcatgtg ggcaacaaat atttctggag atagttcttc
     7501 acaaacggtg ttaaccgcac aagatattgc tgctgcaaaa cttgtaagaa atctaaaaat
     7561 gttttatagc acggccaatc ctcttaatta tgaaaagatt ataagcaaag atgtcacaaa
     7621 tagttcatca aaccaatttg aggtattgta cccaagaaag taggaaatta tgaataaaaa
     7681 agaaataact ttattagtcg cagttccatt ggtttcaatt tcaatcttat ccctaaagga
     7741 aattaatgtt caggcacaag aaagtaatac taacagtcag gctttagaac gtcccgcgtc
     7801 gtcaatcatt gctatgtatc ctatcgctgc ccccagcgct acaacaccaa ataatcaagt
     7861 ttcaaaggaa gacccaaatc cgggctcttc aatcatagct atgtatccag tcactcttgc
     7921 cagctcagca acatcggata gccaaagttc cacagcacct ctgattacag atactccaga
     7981 tgcacataat acaggagatt tcgcagaggg ttctacggtt gaaacaaatt caggcgaaca
     8041 aggaacagat agtagtacct ctccaacaga cacaatgtat ccggaaactg ctacacctgc
     8101 accaaccgag cctgatgata atacaatcgt tcacttaatt gatgctattt ctggtaaaga
     8161 agtgggcacg gtaacgatgg ggcaatggct agaagctttt aaggcagatt acaatggtgt
     8221 tgtgcttccg gggggctatc ggaatgccaa ttggcgttct gatgctcaag gaggaccaga
     8281 actttcaaga actcagtctc cggactatga atatcctgtt atttccacag cagagtatga
     8341 aaacgaaata aatcatgcga cagtcgttgt tcattatatt gatgaagaaa caaatgccga
     8401 agtggggaca tggacctatc ttgtgggtgg acaggttggt tatttacccg gtgactacaa
     8461 aaatcttccc ttcttctatc gtgtcgatac aaataaagca gaggaaaata gtaaacttga
     8521 caatggtcaa atttcccgga aagtttattt gttaaaaatg caagcaaatg caacacctta
     8581 ccccgttcca aattctcaaa gttctgaagc atcaagctca gcaagtcaat caagttcaag
     8641 cgctgcttcg agttcgatta gtggcagttt aatggcaagt tcagctcagg cttctactac
     8701 aacaagcgca agttcaagtg ctgttacaac gacaagtcaa tcgtcaactt caaacagttc
     8761 taaagctgtc tcacaagtca gtagctctgc cacttctaca gcaaaggcat taccaactac
     8821 tgccgataat gcgaaggaat cctttacaat tatgttgatt ggtcttcttt tgtcagtatt
     8881 ttcatatatc ttttatcaaa tgcgtaaaag aatcttcaaa taaaggcttt tgtcagtaaa
     8941 aagaatggaa atataaatca ctaatgattc ttagaagaga tgttagtgat tttttgtgat
     9001 gaattagcac tcgttcgtga aatataagga gatgaaaaag ggcttgtcat ttcattagtt
     9061 ttgggtatta attaacaaat atgagagaat gacttgtgat ataatgaaat aaaatatcga
     9121 aaggagaaaa tcatgcgtga tgccgaaact catggtctag tgctttacag tcgtaattac
     9181 aaagaaaaag ataaattggt caagattttt acagagtctt ttggtaaacg gatgtttttt
     9241 gtcaaaaatt ttggaaaatc cccttatgct agttccttac aagcttttac tgatggaaaa
     9301 ttgacggcaa cgattaatga cgggggattt tcttttatag aggatgtcag tgaagtggtc
     9361 gtttataaaa atattagttc agatattttc atcaatgctc atgcttctta tatcataagt
     9421 ttggctgatg cggccatttc tgataatcaa tacgacccag ggctttatgg atttctaaag
     9481 cgaagtttag agcttttaga tcaaggattt gatatggaag tcgtgactaa catttttgaa
     9541 ttacaagttc ttcatcgttt tggggtttca ttgaacttct cagaatgtgc attttgtcat
     9601 aaaaccgttg gcccctttga tttttcttat aaatttagtg gctgcctttg tccccaacat
     9661 tttgatgaag atttacgacg gagtcatctt gacccaaatg tgatttattt ggtcaatctt
     9721 tttcaagaaa tatctttaga tgaactcaaa aaaatctcga taaaagcaga tatgaaacta
     9781 aaaattcgtc aatttattga tgggctttat gatgaatatg tcggaattca tctcaaatcc
     9841 aaaaattctt ggacggaatg tctgggtggg cagatattat gaaataaatc tgtggataag
     9901 tcgctagaag ttctgttagt aaatttatcc acagtggaaa acttaaaatt actgacagaa
     9961 acctctaaat atttctgtca gtaaaaaatg aggataattt atggactcaa aatcatgggg
    10021 aagagttttt cgtgaaattc gcgaaatgaa aaatttgtca ttagccaaag ttgcaggaga
    10081 ttatgagaat tcaccaaatc ttattacttc aaagcaacaa gtttcacgtt ttgaacttgg
    10141 taaatctgat atcacactca caaaaattta tgagttagtt gaaaatatgg gactttcttt
    10201 tgaagaatat ctttatcatg tcagaaatta tgagcttccg agtggacgag cactttttga
    10261 agaacttgga cgactacaag agcttagtaa tttgtctgaa attgaaaatg tttatcagaa
    10321 attacagatg agatttatag agagtcaaaa tagaatagat tattggagtg ctttagaata
    10381 caagtcattt ttggcacaaa aaaactataa atcttatcag ataagtgaag aggaaattca
    10441 agaaattagt gatgatctat tttccatgtt ggaatggggt gaggctgaac tctttttatt
    10501 tggtgaactt atttattttt tacctgaaac tctcgttttt gagttttcaa aagagctgat
    10561 taaacggaca aagttttatc gaaaaatacc agaaaataaa actcaagtca cccttgttat
    10621 tcgagattgt accaattatt tcattgaaaa atctcaggtg gaacaagctg aaatacttct
    10681 aaatagttat gaaaaattga ttgaaagtcc gattgttgac gtttattctc gtaaagagta
    10741 tctatttgtt gaaggaaatt atcaattttt gattggtaat atagaaaaag gaaatcagat
    10801 ttttgaaaat ttagccatta tgtatgaaaa attaggttat gacaacgcgg caagttatat
    10861 gagagaaaag cgtcacaaat aagtgacgtt tttttatttg gaaaatggag tggtaaaatg
    10921 aatttgtgat tagaaataga attttaattt caactcataa tagaatattt ggaggatttt
    10981 catcatgaaa attacaatca aaaagaacaa aaaagcagaa gatgtacgtg cgcacacaat
    11041 taacaattgc aatagttgtt aaaatgtgaa aattcgtctt ttaaaggcga attttttaat
    11101 aaggagagaa atgatgagaa agttaaatca gtttgtaaag caagtagaaa atgctgagaa
    11161 tatcattcta tataattttt ataatggaaa atcaataaaa tattccaaag ataattttcc
    11221 cacgactgaa agttttatag caaatgatga tatttatgaa ttactaaaat ctgaagaatt
    11281 tttacttgaa aactttaact ttaaaaatcc ttatcaagaa ttagaacgaa cccttcaact
    11341 gattctatta gttcatgaag attgtaattt tagatgcact tattgttatg agaaatttga
    11401 aaaaagggca atgtcattag aaacggctaa tgatattatt aaatatataa ataatgaagt
    11461 caaaaataat agaagtaaat atgataagat tcaactttca tggtttggtg gagaaccttt
    11521 attaaatcta aaaattattg aatatataag ctcttcagta atagaaattg cacgaaagaa
    11581 taagattgaa tatagtgctg atatgactac gaatggctac cttttaaatc caagagtttt
    11641 tcaaaaattg gtgaatttga aagttaaaag ttttcaaatc acagtagatg gtggacaaaa
    11701 atatcatgat aaacaaagaa tactaaaaaa tggtcatgga acttatgaaa gaattatcag
    11761 taatttatta ttaatacaag aaatgattcc atctgatatc tttattgtgt taagaacgaa
    11821 tgttggagaa gaaaattata agttcatgga ggagtatatc catgaatcaa tcataaattt
    11881 tggaaagtgt gaaaatattt tgttcgcctt tcataatatt ggtaattggg gagaaagaaa
    11941 ttcaaaaatt attgagaaag atgttcgttt tgaactggct agtaaagtta ttgagcaagg
    12001 agggcgcacg gttccgttta tttggtctat gaccgcttcc aatttatgct atgcttcaat
    12061 aaaaaatcac tatgtcatag ggtcagatgg attagtttat aaatgtacag tagcacttta
    12121 tcaagctaat aatattttag gtagaatcgg taagggcgga aaactattaa ttagcgaaaa
    12181 taaagagtca ctttgggtaa attctactga aactgaagaa tgtaaaagct gctcggtatt
    12241 acctatctgt atgaataatc gttgtccctt gaaaagatta aatgctgata gcttacagta
    12301 ctgtatttcc tcaaaagata agacttctga tatgatttta atgttagaaa agcaaaattt
    12361 gattacttat gagattggaa ttgaggttta aaatatgctc acttacatta aaaaaaacaa
    12421 atttcagaat atcattctac ttctcataat tatcactaat atggctttat atgtttatgg
    12481 gaactatctt aaagtcaatt tggttaatgc tttgatgaaa tcaaatattt ccaaagggct
    12541 cttttggttt cttcttagct taattatttt tctaatcatg atgattatta gaaaaataga
    12601 agtggttcag acagaaaaaa caacacaaac ccagttaaat ttaatccgaa aagatatttt
    12661 aaaaaatttg acttcactta cttatcagga attttctaaa gagagcaagg atcaatacaa
    12721 ttcgtggtta aataatgatg caatactctt agacacagat ggttataaag aaatatattt
    12781 catgatagaa aatatttttc tggtgctttt ttcaagtttt gccttattta cttttcattg
    12841 gattcttttt gcgacaaccc ttggcttagc tcttattttg ttgattcttc caaagttatt
    12901 tcaaaagaaa atggtcaaag cgacccaaga ggtgtcaaat agtgccgaaa aagcattaaa
    12961 agaaagtaat gacaaactca aaggttatga agtaatttat cacaatcagc agtttgattt
    13021 tttaacttct cgcttgcttc aagtttatga gcaactaaaa gcggtaaaaa taagcaaagc
    13081 aaagttagtc tcgacagcaa tgatgtgtac agttggcctg agttttcttt cacagtccgt
    13141 aattttgggg gtcaatgcac ttttagcttt tcagcatatt gtccttttag ggacattatt
    13201 agtttcagga aattttgctg gtaatatttt taatggactg aataccattg ctgattgctt
    13261 cactattgct ttaggaactg ataaattact gacgaaatat ccgaaagtat caaatcaaag
    13321 agaaagcaag tctgtcagta cttttgagaa gaaattatct tttgaaaatg tttcgattaa
    13381 attaggagat aagaaaatta cttatccaaa ttttgaaatt aaaaaaggga aaaagtacgc
    13441 aatagttggt gagagtgggt caggaaaaac aacattaatt caattgctca atggagattt
    13501 agaagattat caagggacta ttaagttaga tggtttagat tacaaaatta ttgataaagg
    13561 gaagctacaa tctatcattg caacgattag ccaatttccc tatcttttta atgacagctt
    13621 agaagaaaat ttaaaaatga atcgagaaat tactgacgaa aaattagaaa aagtgttgaa
    13681 agaagtcaaa gcagaggact ttttaaaagg caagctgacc aataaatttg ataataattt
    13741 atcaggagga caacagcaaa gagtggctat tgctcgggaa ttattaggag aaaagccaat
    13801 tttaattatg gatgaaagta cggctagcct tgataagttg acagctctag ctgttgaaca
    13861 aaatatatta caaaatccaa gtttgacagt aattatgatt actcaccatt tttatgatga
    13921 aactcgtcct tattttgatg aagtcataga attataaaaa tttactgaca gattttccgt
    13981 tagtaaattt atccatagaa aaaatcactg acagatttgt cagtgatttt taattttatt
    14041 aaacgtgaat tggtaagcca tcagccaatt cagctgtatc cataatcgct tcaccaagtg
    14101 ttgggtgagg ttggatagtc aatgaaatgt ctttagaagt caatccattt tcaatcgcta
    14161 gtgacaaacc agaaatcaag tcagatgcac cagggccaac gatttgagca ccgattaagg
    14221 ccccttcttt agtttcagta atcaaacgta agaaaccagt ggtatcattc attgaaatgg
    14281 cacggccatt tgcagcaaat ggaaacttag aaattttaac atctttacgg tctttaactg
    14341 attcaggcgt ttctccaact gttgccaatt cagttgttgt ataagctaca gcaggcaaag
    14401 caacgtgtaa gtccacgtcg tcctcagctc cagcaatcgc agcagcagca actttagctt
    14461 ggaaagaagc tttgtgagcg agcattggac caggaaccac atcaccgatt gcataaatgt
    14521 gaggaacatt agttgcataa gaatcgtcaa cttcaatcaa accacggtca gtcaatttaa
    14581 catcagtgtt gttcaagccg attaaatcag tatttggacg acgtccaaca gaaacgagta
    14641 agtaatcacc agtcactgtt tgttcttttc cgtcaacctc aaaagtcaaa gttacatctt
    14701 tatcagtttg agtagctgat ttagccattg ctgaagtaaa gatttcagaa ccagcagatt
    14761 taacgcgatt agcaatgata tcagacattt ctttatcaaa cccgtttaaa atgtggtcca
    14821 aaccttcaac aattgtaatc ttagaaccga gcatacggta agctccacca agctcagaac
    14881 caataactcc tcccccaaca ataatcaaat gtttaggaac ttctggaagt gacaaagcac
    14941 cagtagagtc aataatgcga ccaccaaatg ggaaagaagg aatttcgata ggacgtgaac
    15001 cagttgaaat aatcacatca ttaaattgca aaagttggaa cccatcttct tgttcaacat
    15061 tgattgtatt gttatcaata aattctgcag ttccttgaat cacgtcaact ttgtgttttt
    15121 taagtagcat tttaacgcca cctgtcaact ggttgacaac tttatcttgt ttccattttt
    15181 gggcagattc ccagtttaat ttaacatttc cgacagaaag cccaaaagga ttttctcctt
    15241 tttcttcctc cagagattct tggtaatgat gaccaatatt aatcaatgct tttgatggga
    15301 tacaaccaat atttaaacaa accccaccaa cattatcttt ttcaataatt gtaacttttt
    15361 taccaagttc agccgcacgg atggctgcaa cataaccacc agggcctgaa ccaataacaa
    15421 ccaaatcaac ttctgttgct tgtgcaccaa caaccataat atatcctctt tcttgtaaac
    15481 attagtgtca acttgaattt acaatactgt aaactagttt tttaaatcta tgacagaaag
    15541 aaacgaaaac aatatttttt cgttccttta ctaataagac aattagcgag tatcctctag
    15601 gagactcgtc tgtaatgaat agatgcttta gcaccattta ttacagacta ttagatttcc
    15661 ataagcatga actcagggtc agccaataga gatttcaagt agttaagtga tgtttgacct
    15721 aacatcccat caatcaaacg gtggtcataa gtcatagaca atttcatgtt ttgtccgaca
    15781 acaatttcgc cttcaccatt aacaattggt tctttaacga ttgaacccag tcctaaaatt
    15841 acgacatcag aaccattaat gattggtgta aaccaagaac cacgagcaga tccaatattt
    15901 gaaattgtaa ttgttgaacc ttgcatttgt tgaggtttaa gtgttccttc tcgtgtagca
    15961 gtagctaatt cagcgatttc tttagcaatc tcaagaattg atttagtctc agcttcatga
    16021 atcactggaa cgtacaaacc agttggagca tttacagcga ttccaaggtt gacatgttca
    16081 tgataaacaa tttcttgttt ttcatagtca acagaagcat tgatatctgg gaatttatga
    16141 gcagtagtag ccaaagcttt agcaacataa gcaagataag ttaatttaat atcttgtttt
    16201 gcagcaattt ctttaaagac agcacgatgt ttcacgagtt tagaaacttc aacttggtca
    16261 aagtttgtta ctggtggaat gtgtgtatgt tgagcagtca tgactttaga aacaacttta
    16321 cgagttggat tcattgcttc acgtcgatca ccagtccctg ctttaacgct tggcgctttt
    16381 tcagcaacag gagcagctgg tttatcagcc ttaggtgctg gagcagcttc tggtgctgtt
    16441 tgagcgatag gagcgacatt gccagattca aaagctttaa catcggccaa tgttgtgtgg
    16501 ccgtgacgac cagttgcagg aacttgactt agatcaatac cagccttgcg tgcataatga
    16561 cgaacagaag gcatcgcaag aatgtgacca gtagaagttg ttttagtcaa tggagcattt
    16621 gcaggacttg caggacttgc aggactagct gctttaggtg cttctgcgac tggagcagga
    16681 ctagcagctg ctggagcagc cccatttcca ttgtactcaa ttaaaggagc cccaacttct
    16741 acagttgttc cagcttcaac gaaaagttta gtgacttttc cagaatatgg agaaagaatt
    16801 tcttgcatga gtttatcatt ttgaacctct gcaacaggat catcttcttt aatttcatct
    16861 ccaactttaa ctaaccagtt ggcgatatct ccttcatgca ttccttcacc aatatcaggc
    16921 atcgtgaaga tttgagattc tccagaaggt gcatcagttg tagcagtatc agaactagct
    16981 gtttcttgag gagcaggagc agctgcagaa gagcctgaac cgtcaccatc aaactcaacc
    17041 aaaggagaat caacttctac agttgttcca gcttcaacga aaagttttgt tacggtacca
    17101 gaataaggag agagaatttc ttgcataagt ttatcatttt gtacttcagc aattgggtca
    17161 tcttctttaa caacatctcc aactttaact aaccagttgg caatgtctcc ttcgtgcatt
    17221 ccttcgccaa tatcaggcat tttaaaaatc tcagtcatag tcaaccacct ctttaacttt
    17281 attcacaata tcttcagctt taactgccca gtcattttct gcttgtgcaa atgggaaaat
    17341 tgagtcagga ccactaacac gtccaattgg cgctttaagg ttcaaaacaa aacgttctga
    17401 aatttcggcc atgacattcg ctgcgatacc ggctgtacgt tgagcttctt gaacaacgac
    17461 cacacgccca gttttttcaa ctgttttacc aattgacgca atatcaagag gagcaactgt
    17521 tctgaggtca aggacttcag ctttaattcc atctttttcg agttgttcag cagctttaag
    17581 agcaagtgga actgttccac cataagcaat gattgaaaca tcagagcctt ctttagcgac
    17641 tgcagcagta tcaagtggtg tagtgtaata accttcagga acttcacctt taagtgagcg
    17701 ataaaggtga aggttttcaa ggaaaataac agggtcgtta ttttcaattg aagccagcaa
    17761 taatccttta gcatcagctg gatttgaagg cattacaaca cgaattccgg ggatttgtga
    17821 aaatagccct tcaattgaat ccgcgtgcat ttcaggcgtt ttagttccga ttccataagg
    17881 tgtacgcacg acaatattat ttgaacgtgt gttattaaaa cgataacgtg tccggctcat
    17941 ttgtccagca attgagtcga aaacttcaaa gataaaggtt ccaaattgaa tttccataat
    18001 tgggtggaaa ccttgtgttg caagaccaat tgccattcca ccaattcctg attcagcaag
    18061 tggagtattg aaaacacgtt cttctccata ttttgcttgc agaccatcag tagcacggaa
    18121 aaccccacca ttttgtccaa cgtcttcacc aaaaatgagt gcatctttat ctttttcaag
    18181 cgccaaatca agcgcttctg taattgctgc aatataagtt tttactgcca ttcttatttg
    18241 ccctcgcttt caaattttgc aatttgttct gccattgctt ggcttggcac ttcaagtgta
    18301 tttttaatga agctagaaat tttttgtttt tcaacattat tggctttctt aatgtcggca
    18361 tcaatacctg catcaagttc agcaatataa gcttcctctt tctctgtatc ccaaagtcct
    18421 ttttcagtca ggaaattacg catacgaacg agaggttctt ttttccacca agcttcaatg
    18481 tcttctttag tacgatagcg aagtgggtca tcaccagctg ttgagtgtgg ttctaaacgg
    18541 tttgtaattg cttcaataac aactggacca tttccagcta ctgcccaagc acgagcttct
    18601 ttggaagcaa gatacatagc aatcgcgtcc attccatcaa ctacgataga aggagcacct
    18661 gcggcccaac ctttagcagc taaatgagga gcggcacttt ggagactacg aggtgtcgaa
    18721 attgcatagc cattattttg gataaaggca acaagtgggg ctttataagc tccagcaaag
    18781 ttaattcctt cataagtatc accttgtgaa gaaccaccat cacctgtgta aacgaaagct
    18841 acagcatctt ttttacgttt tttgagtccg agtgcgacac cagcggcttc aacgtattga
    18901 gcaccaatga taatttgtgg gaaccatgag tttacaggtt taccatcatc ggtagtgtac
    18961 tcattaccaa gttgatgtcc acgagaccaa agaagacctt tccaaattgg ccaacctttt
    19021 gcgtaaattt gtggcaagtc acggtaacct gggaagagcc agtcttcgtc agagaaagcg
    19081 aatgatgagg ccatttgaga agcttcttga ccagcgtgag gtccaaagaa tcccatacgt
    19141 ccttgtttag ctaatttcat tgaacgaatg tcaacttgac gtgcaaaaag catactttta
    19201 aagagttcaa cgagtttttc atcagaaagt cctgcacgtt taagaccctc ttcgtcaaca
    19261 attttccctt cttcgttaag aatttgaagc attggaaatg tagtgtcttg cagttctagc
    19321 tgcgctttga aatctaagat ttgttctgaa tttgacataa tagattccct ttctatttta
    19381 tgtgtctata attagaaatt tatcattttt tggagaaatt tcctaaggtt atgcttgtga
    19441 aataacttaa tctgttcggt agtcagcttt gaacatttca gaaagttcag tattttgaat
    19501 tgttccaaaa tattgtcctt ctttatttgt ttcaaggact tcaagaattg ctgaaggttc
    19561 aaattctaga ccaataaatt gctctttgat atctcgccaa tctcgaacgc ctaagaaatc
    19621 tccttggaaa ttaatttcag tgattttacc attttcaaca ttgacttgaa tatcaatggc
    19681 tccgccagta aatttagcgt gattttggaa ggagaatttt ggtgattcgc cataattcca
    19741 atcccaagtc gcaaattgct catctcgtat ttttttgatt gagctaagtt ggtcatcagt
    19801 taaaactaat tcaccatctt ttccttcgtc tgtgagatag tattttaatg cgtcaataaa
    19861 actatctaag gttaagtcct caggggcaaa atctttgata tttcccacac gagcgcgaac
    19921 tgatttagcc gctttactga caaatttttc atcagaaaca ttgagagaac gaatcattgc
    19981 ttcaacatca gtgtcccaaa ggagggttcc gtgatgcatc aaataacctc cagcatagcg
    20041 ttgggcattt cccgaaatct ttttaccctc aacttcaagg tcattgcgtc cagtgatttc
    20101 agctttgatt ccaacagcat ggagtgcttc atacatcggt tgaacaaatt ttttaaagtt
    20161 gacagagcca gaattttcga caggaacaaa aaaggtgaaa cagatgtttc cttcatcatg
    20221 ataaactgca ccaccgccag atactcgacg aacaacttga acatcatgac tgtcaatgta
    20281 gtcttgattc acttcagcaa aagtgttttg gttgcgcccc acaataactg cacgtttatt
    20341 ttgccataaa gcaaaaacag gctcagttgg ttttaggtga taaagcagcc agctgtccat
    20401 cgcgatattt gtgtaagcgt cttgacctag atagttaata tattgcatgt ttatgcatcc
    20461 cttccaaatc cttgtgctta ttttgtcaaa taagtttgac aaaataacac gcacgattta
    20521 attataccct ttgtgaaaca aaatgtaaag agaaatgctt tacgcttaca attactgtac
    20581 tatgtgattt tcacctcaaa atattgtgaa atagatatca tttgtgacag atgaaaaaaa
    20641 gaccagtcta ttttgactgg tcttggattt ctcgacgaat ttcgagggca cgttccggaa
    20701 aatcggtgat gattccagcg acatgttgtt gaaaagcttg tcgcatttct gtttcttgat
    20761 taactgtcca gagacgaaga ggtctttttg aacttttgag aagaagtggg tgcttgaagg
    20821 cgtaggttct tcggggatga attccggaaa taaaatctgt tgagctgcct ttataatgac
    20881 tttttagggt caaaagattt ttcgtcagat aattaacctc agcctttgaa tcaaaagtgt
    20941 gtattttttt taatgaatcg aaattaaacg aactataaat atagctaaag ggccatttag
    21001 tttctgtcat taagtctgag agcttttttt caattccggg atagtcaaat ttatcagttt
    21061 taatttcgat atttaaataa ccagtaaatg ataggtctgt cagtattttt aaaacctctg
    21121 acaaagttgg aattttttcg tcagtaaatt ttgaattgaa ccaagaacca gcatcaaatt
    21181 tctttaaatc tatagcattc atatttttga caagaccttt accatttgtt gtccggtcaa
    21241 ttttctcatc gtgaataaca attaattcat tatcgagtga taagtggaca tcaagctcaa
    21301 ttccgtcagc gtggacacga acagcttcat gaaaagcggc caatgtattt tctggacagt
    21361 tggatttaga accacgatga gcaaaaacca atgttttaga agtgaggctt ggcttgaatt
    21421 tcaaattgtt tttgatttta tttctgtcaa gaaaattatg aagtttaaaa actatttttg
    21481 tgaagccaga catgagtcac ttcctttcga tttgagcata atttttactg acaaggccat
    21541 aaaaaagtgc tggtagggtc tgtcagtaaa aattaaagaa gagtttcctt gtattcttct
    21601 tcgatttggc tgacaaaaag gtgcattatt ttatcacgct tttcgcctag tctttttcct
    21661 tcggttgtat ttaataaatc ttttaacaaa aataattttt cataaaaatg attgagtgtg
    21721 gagttatttt tttgactatg atagtcttct ttagaattgt aatctaaagg tggcagattt
    21781 gggtcataaa agactcgatt ttttgcccaa ccatattcaa gtgtccttac aattccccaa
    21841 gctcccattg catcaaggcg gtcagcatct tgcacaattt gtccattcaa agagagtgtt
    21901 tttctctcga ttaaattact tgaaaaactc atgttgtcaa taatcataaa aagttcatca
    21961 atgagctttt tatcaatttt aagctcattt aaaaattgcg caacttttgc tttttgttta
    22021 ggaacatcct ctgttaattt ttcatcataa gtatcatgta aataacaagt tgctagaaca
    22081 agttcttgat ttgctgacgg ctctgtcagt aaaatttttt gagcaagagc aacgacccgt
    22141 tcaatatgat caaagccatg tccatcatta tttttatcat gaatttcttg agcaaatctt
    22201 ttaattttct ttaaatcaat caagttaaat ctccaaaata aatgacttga gtttacacca
    22261 gtgtcaacta aaaccgaata gtgtaaactg gcaaatcctc aagattagta aggctaagga
    22321 agtgaaattt gaaaatgaat tacttgaaat agttgattcc catagcagac ttaacttcat
    22381 caagagtttg a
//
