LOCUS       NZ_CP065920            21711 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus pseudintermedius strain SP_11306-1A chromosome,
            complete genome.
ACCESSION   NZ_CP065920
VERSION     NZ_CP065920.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2605463)
  AUTHORS   Byukusenge,M., Banovich,F., Li,L., Kuchipudi,S.V., Jayarao,B.M. and
            Naikare,H.K.
  TITLE     Complete genome sequences of Staphylococcus pseudintermedius strains
            isolated from canine superficial pyoderma lesions in Georgia, USA
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2605463)
  AUTHORS   Byukusenge,M., Banovich,F., Li,L., Kuchipudi,S.V., Jayarao,B.M. and
            Naikare,H.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2020) Veterinary and Biomedical Sciences,
            Pennsylvania State University, Wiley Ln, University Park, PA 16802,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 233x
            Sequencing Technology             :: Illumina & Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016126755.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 13:13:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,469
            CDSs (total)                      :: 2,387
            Genes (coding)                    :: 2,345
            CDSs (with protein)               :: 2,345
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 13 of 42
            Pseudo Genes (incomplete)         :: 29 of 42
            Pseudo Genes (internal stop)      :: 14 of 42
            Pseudo Genes (multiple problems)  :: 12 of 42
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:44:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2275794
            Orig. end                         :: 2297505
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065920.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21711
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="epipeptide"
                     /region_number="8"
                     /rules="(TIGR04078 and yydH)"
                     /tool="antismash"
     cand_cluster    1..21711
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04078 and yydH)"
                     /kind="single"
                     /product="epipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21711
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11711](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04078 and yydH)"
                     /neighbourhood="10000"
                     /product="epipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11711)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04078 and yydH)"
                     /neighbourhood="10000"
                     /product="epipeptide"
                     /protocluster_number="1"
     gene            complement(457..714)
                     /locus_tag="JC281_RS10770"
                     /old_locus_tag="JC281_10770"
     CDS             complement(457..714)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219918.1"
                     /locus_tag="JC281_RS10770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10770"
                     /product="hypothetical protein"
                     /protein_id="WP_020219918.1"
                     /transl_table=11
                     /translation="MCFSTEDVQHYLALVNDTNPIHTDIVPGQLVVQYVCVEAGVEPIA
                     VRYKNTIGVDEQVTWQRDNMQIQVSGIDEQLKIVIEVKAS"
     gene            complement(714..1085)
                     /locus_tag="JC281_RS10775"
                     /old_locus_tag="JC281_10775"
     CDS             complement(714..1085)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614707.1"
                     /locus_tag="JC281_RS10775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10775"
                     /product="hypothetical protein"
                     /protein_id="WP_015728646.1"
                     /transl_table=11
                     /translation="MQHFLNVGDREVKAYCFDKSAVQRYQQFFNMPQTTTVPLLMTARV
                     WPLFSLFRPFKETAIRLVATEIETHYPLKVGEHYQVTMAVLKVQQIKSFQRYQMALSFD
                     QADTCHCRIIQTFVSRRVS"
     gene            complement(1054..2199)
                     /locus_tag="JC281_RS10780"
                     /old_locus_tag="JC281_10780"
     CDS             complement(1054..2199)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614708.1"
                     /locus_tag="JC281_RS10780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10780"
                     /product="thiolase family protein"
                     /protein_id="WP_014614708.1"
                     /transl_table=11
                     /translation="MTKAVIVAAKRTPIGVYGGQLQKWEPEHLLKPLFEHFEATLSCSL
                     NDLDDVILGNIVGKGGNIARKSLLEAGIDVSVPGLTVDRQCGSGLEAIHLASRLVESGA
                     GDFYIAGGVESTSRAPWKMEKPTSLYPTTPPTFYERAPFAPVGQDPTMIEAADNVAKQY
                     DVSREDQDRFAVQSHHRASKAIATGAMSAEILPLIVKGQQMIQDESVKPHLQYERIARL
                     KPLREGGTVTVGNCCLKHDGACLVVVMSEQKARELGMSEGLMFMDYAVEGVDPHVLGIG
                     PVPAVQRILERQQRTIDQIDAVELNEAFSAQVLASARALNIQEAQLNRYGGAIAIGHPY
                     SASGAILVTRLFYMKDAQSTIATMGIGGGMGNAALFERWRP"
     gene            complement(2196..3545)
                     /locus_tag="JC281_RS10785"
                     /old_locus_tag="JC281_10785"
     CDS             complement(2196..3545)
                     /NRPS_PKS="Domain: AMP-binding (7-351). E-value: 2.7e-44.
                     Score: 143.3. Matches aSDomain:
                     nrpspksdomains_JC281_RS10785_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728644.1"
                     /locus_tag="JC281_RS10785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10785"
                     /product="AMP-binding protein"
                     /protein_id="WP_198456089.1"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-35, bitscore:
                     117.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKRLETYAVERPEHIAIRMDDVTLTYESLWRDVQKESEALPTNI
                     SHQNVMLTHTQTLDFIVAYLAALIRQGVPCVLGPQWSTEQRDALIKLHRMPYVWGDEGL
                     TSTSHEPAHKAPMIPQCLHIGFTSGTTGLPKGFMRDLPSWIASFEVNDTLLDASTQTYM
                     ALGPYAHSLTLYVLIYALWNGKTFIGQDRYDMAKSLVYVAELQQTCALFIVPTMVYDGI
                     HLGEQSQWVRHIFISGDKLPASRHTQLKKIFPESAIDEFFGTSEASFISVNRNQTAPLD
                     SVGRLFPNVTVTLRERDDAGIGQLFVKSPMTFSGYLGEASVNEWIATGDYARIENDVLY
                     LKGRVQDRLIIGGKNVYPAVIEQHLKQRPEIVDVVIVRLPHDKLGELAIALYTGPEQLD
                     IQAVRHWLSSRVSRYEIPSKFIYVATLPYTESGKVSRKMAQTCYERGDYQ"
     aSDomain        complement(2493..3524)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JC281_RS10785_AMP-binding.1"
                     /evalue="2.70E-44"
                     /label="JC281_RS10785_AMP-binding.1"
                     /locus_tag="JC281_RS10785"
                     /protein_end="351"
                     /protein_start="7"
                     /score="143.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="YAVERPEHIAIRMDDVTLTYESLWRDVQKESEALPTNISHQNVML
                     THTQTLDFIVAYLAALIRQGVPCVLGPQWSTEQRDALIKLHRMPYVWGDEGLTSTSHEP
                     AHKAPMIPQCLHIGFTSGTTGLPKGFMRDLPSWIASFEVNDTLLDASTQTYMALGPYAH
                     SLTLYVLIYALWNGKTFIGQDRYDMAKSLVYVAELQQTCALFIVPTMVYDGIHLGEQSQ
                     WVRHIFISGDKLPASRHTQLKKIFPESAIDEFFGTSEASFISVNRNQTAPLDSVGRLFP
                     NVTVTLRERDDAGIGQLFVKSPMTFSGYLGEASVNEWIATGDYARIENDVLYLKGRVQD
                     RLII"
     CDS_motif       complement(3132..3176)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JC281_RS10785_0001"
                     /evalue="1.50E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="JC281_RS10785"
                     /protein_end="138"
                     /protein_start="123"
                     /score="14.6"
                     /tool="antismash"
                     /translation="IGFTSGTTGLPKGFM"
     gene            complement(3756..4442)
                     /locus_tag="JC281_RS10790"
                     /old_locus_tag="JC281_10790"
     CDS             complement(3756..4442)
                     /EC_number="5.4.2.11"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501165.1"
                     /locus_tag="JC281_RS10790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10790"
                     /product="2,3-diphosphoglycerate-dependent phosphoglycerate
                     mutase"
                     /protein_id="WP_015728643.1"
                     /transl_table=11
                     /translation="MPKLILCRHGQSVWNAENLFTGWADVDLSEQGHNEAITSGKKLKE
                     QEIQIDIAFTSLLKRAIKTTFHLLNESDQLYVPVVKSWRLNERHYGGLQGLNKDEARQQ
                     FGEEQVHIWRRSYDTPPPAQDEAQRERYLKDRKYELLDRRVMPESESLKDTLVRVIPYW
                     NDQISQELLADKTVLVAAHGNSLRALIKYLEGVSDEDIVGYEIKTGAPLIYELTDDLKV
                     IDKYYL"
     gene            complement(5060..5524)
                     /locus_tag="JC281_RS10795"
                     /old_locus_tag="JC281_10795"
     CDS             complement(5060..5524)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="JC281_RS10795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10795"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_225549901.1"
                     /transl_table=11
                     /translation="MGKSMLFNFIQHPEQYDIVGEYDIHLPEKTSVVDQKYVYQDDHNQ
                     WFQTLPQPQKEKFLHLLYQLGVEKKKFTARQTEGWSDGEKKKVLIAHSLIQQSSLLMWD
                     EVTNYLDFYVVDQLIDMLANARPTMIGIDHNAHFVETIASKTIQLVRDEE"
     misc_feature    6006..6017
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            6049..6372
                     /locus_tag="JC281_RS10800"
                     /old_locus_tag="JC281_10800"
     CDS             6049..6372
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013828.4"
                     /locus_tag="JC281_RS10800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10800"
                     /product="ATP-binding protein"
                     /protein_id="WP_257784254.1"
                     /transl_table=11
                     /translation="MWFLGNRGTDKTHLAISLGIEVCKQNIKTRFYTFKELIELLTTSE
                     EKGLTNKTLKQLNRIELLIIDEIGYTPISKEQADLFYQLMSLRYEMKSTIITTNIPFSS
                     WGD"
     gene            complement(6809..8039)
                     /gene="ltrA"
                     /locus_tag="JC281_RS10805"
                     /old_locus_tag="JC281_10805"
                     /pseudo=""
     CDS             complement(6809..8039)
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ltrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219999.1"
                     /locus_tag="JC281_RS10805"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JC281_10805"
                     /product="group II intron reverse transcriptase/maturase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYRKSPSLMELVVRPENIEKAIKKVKKNKGAPGIDGMKVSELHAH
                     FAQYFSQITKKLLDGSYQPQAVRKVQIPKPNGKMRVLGIPVARDRVIQQAIRQVIEPGI
                     DRTFSNHSHGFRPHRSTGTALKQCADYYEEGYKIAVDCDLKQCFDMLNHDKLMYLFERH
                     VQDKSISTFIRRSLQVGAIDLSGEVTERKIGAPQGGVISPLLCNIYLHELDKELEKRGH
                     RFVRYADDFVIFVRTKRAGERVMTSVTKFIEKQLKLVVNEEKSKVGAVTRLKFLSCLIT
                     KVNGVCRFRPTMEAKRNLIRTLRKITKRNRPGTFKDIIIEINQVTRGWINDFGRGFIRG
                     FIETTQSWLNRRLRQLILKRWKRVRTKYKMLRQYGLDHRSAMKIAQSRKKILAIIEYAR
                     GSSCTYNKITL"
     gene            complement(8616..9338)
                     /locus_tag="JC281_RS10810"
                     /old_locus_tag="JC281_10810"
     CDS             complement(8616..9338)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670189.1"
                     /locus_tag="JC281_RS10810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10810"
                     /product="peptide ABC transporter permease"
                     /protein_id="WP_014614713.1"
                     /transl_table=11
                     /translation="MKLEFKKSISNKILMTLSILFVFSFLLGYFLPVGIDKVTNLDYPK
                     YFFSAYTVLTEFGFLLFSFIISYFINKEYSNKSLLFYKLIKENIYSFFYKKASILFLES
                     LAIIVVGITIISMVFSDFSHYFFLIIMFLLVVLQYILVVGTISIVSPNVLISIGLSIVY
                     WIASIILVAINKEMFGFLAPFEASNSMYVSVEKVLNGEIPTINLHDVLTIALFFTFVFI
                     VNFIVLGLSKKRWLKLGL"
     gene            complement(9353..9988)
                     /locus_tag="JC281_RS10815"
                     /old_locus_tag="JC281_10815"
     CDS             complement(9353..9988)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006191156.1"
                     /locus_tag="JC281_RS10815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10815"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_014614714.1"
                     /transl_table=11
                     /translation="MEIVDYSLKVKGKELINNCNLKFYSGEINHIVGKNGVGKSQLAKD
                     FILNNSGSIPKSINKGVTLISSSSNVPHDITKEFLLNLLKARFPGAQKTFSKISEILNI
                     NDIPSKVLIKNLSDGQKQKLKFLSFLLEDNSLIILDEITNALDKKTVNEIYIFLNDFIK
                     EHPSKTVVNITHDLSDLSSLPGKYFIFKNQKIEEYNSKDQLIDDYINL"
     gene            complement(10001..10768)
                     /locus_tag="JC281_RS10820"
                     /old_locus_tag="JC281_10820"
     CDS             complement(10001..10768)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     epipeptide: yydH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614715.1"
                     /locus_tag="JC281_RS10820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10820"
                     /product="peptidase"
                     /protein_id="WP_070407647.1"
                     /sec_met_domain="yydH (E-value: 2.8e-153, bitscore: 507.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPLKYEDKEYEILIQNHVFIKDKKTNSYYRNNMNSIDEKMLKKF
                     NSYPEKVNCFLFFTYMLLSVIVIITNILYTLYLQKNIIIIFENEVTVVLILYFLVSVFL
                     HELGHIYSLKFFGRKIDKFGFRLNFYVFPSFYVQMNETYMLSKIDKIIVHSFGLFINII
                     SINLLQLMNILIIDSYALTVAYMFFSSTLLWNLVPILNSDGYKIMMVALSLDEFNNFTK
                     NHWLILIFQTIGVVIALNTIIHWVFYWIKNISI"
     gene            complement(10749..11711)
                     /locus_tag="JC281_RS10825"
                     /old_locus_tag="JC281_10825"
     CDS             complement(10749..11711)
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     epipeptide: TIGR04078"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226981.1"
                     /locus_tag="JC281_RS10825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10825"
                     /product="YydG family radical SAM peptide epimerase"
                     /protein_id="WP_014614716.1"
                     /sec_met_domain="TIGR04078 (E-value: 1e-139, bitscore:
                     462.4, seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.7e-12, bitscore: 43.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 9.1e-09, bitscore: 32.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDKSVSINLTSKCNATCDHCCFSCSPKSTIKMEDFYIRETVLEF
                     AKDSNVEVISFTGGEIFLNYEFLEELLKITKNYNKKVTLISNGFWGNSRKLLEKYFSDF
                     YKYNVVALTISYDEYHSPFVKLKSIKNIFEYRMKYPEIQVSLNMAVTKDKMSDNILREL
                     GSSILGAKITKFPMISVGAAKDKISKENIHNFYNINKDREVLYCPGFEIVYHHDGEIYP
                     CCSPAIFETPITLRENKNQTLTRTVEKLNSNLLLYIIRKEGFNWFLDILREENMLHQFD
                     IPTDFPSVCSICGSLFSTEEKIKFFKPFMEAYYYETIEV"
     gene            complement(11767..11931)
                     /locus_tag="JC281_RS10830"
                     /old_locus_tag="JC281_10830"
     CDS             complement(11767..11931)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002486687.1"
                     /locus_tag="JC281_RS10830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10830"
                     /product="epipeptide YydF family RiPP"
                     /protein_id="WP_014614717.1"
                     /transl_table=11
                     /translation="MKKEINSYKSTKENTMKDLEFKKLVNDSEKLAKVNDLWYFVKSQS
                     NRWIVGSGH"
     misc_feature    complement(12005..12018)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.28"
                     /tool="antismash"
     misc_feature    12005..12019
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.7"
                     /tool="antismash"
     gene            complement(12883..>13485)
                     /locus_tag="JC281_RS10840"
                     /old_locus_tag="JC281_10840"
                     /pseudo=""
     CDS             complement(12883..>13485)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /locus_tag="JC281_RS10840"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10840"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="WKKRNAKRIEREKKDEKDFELILAAFNKRGYSKGSRSIHMTLLHQ
                     GVVMNRKKIIRLMKKFNLVCPIRKSNLHKQAMKYSNEQRVKDNLVNRHFKMGGPKTILL
                     TDITYLYYGKGKIAYLSTIKDAYTNQILSYELSESLKVDIVLNTVSKLMKKHHISKNKK
                     LIIHSDQGIHYTCTSFQELVSASGLKQSMSRKRELLG"
     gene            complement(13572..14003)
                     /locus_tag="JC281_RS10845"
                     /old_locus_tag="JC281_10845"
     CDS             complement(13572..14003)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042545.2"
                     /locus_tag="JC281_RS10845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10845"
                     /product="HTH domain-containing protein"
                     /protein_id="WP_041613294.1"
                     /transl_table=11
                     /translation="MSKRLFTEDEIADLKSNKYVLNVSPKAITYTEEFREHFVEEYENG
                     KTPSQIFKEAGFNTKILGRRMSNFRERVLMMKDRPEGLQDTRKENSGRPRLSEMTLEEE
                     NNYLKHKIQLQNQQIEALKKTNSINRRASKAMRKKNSNS"
     gene            complement(14136..14993)
                     /locus_tag="JC281_RS10850"
                     /old_locus_tag="JC281_10850"
     CDS             complement(14136..14993)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614719.1"
                     /locus_tag="JC281_RS10850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10850"
                     /product="oxidoreductase"
                     /protein_id="WP_070407648.1"
                     /transl_table=11
                     /translation="MKIAIIGPGAVGTAIASVLDTLDVTLLGRQDKVMTFEERDTGERK
                     SIPVKALSSVTTTFDVVFIAVKTHQIDTILPQLKTITHAQSKVILAQNGSGLLPKLEGY
                     DAYQAVVYISGEKQEDKVRHDKDYRIQLKQDAFTEQLKAVISTTALTLELEDNIEKAIW
                     FKLIFNLGMNTLTALSRDTARLLKDDSMLELCKNLLKEGLQVANAEGITYEDSFVDDVI
                     AAYRIFSDESATSMYYDTMNERVTEVEAIQGYIYRQGQKHQLHIPYIETTYTLLAHQNE
                     VRQR"
     gene            complement(15486..16169)
                     /locus_tag="JC281_RS10855"
                     /old_locus_tag="JC281_10855"
     CDS             complement(15486..16169)
                     /EC_number="1.5.1.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219923.1"
                     /locus_tag="JC281_RS10855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10855"
                     /product="flavin reductase family protein"
                     /protein_id="WP_198456090.1"
                     /transl_table=11
                     /translation="MEYSPKQGVRSHGLPYDPFKSSTVPRPIGWISTVSKDGKDNLAPY
                     SQYQNLTWDPPMVMFAANQSVLGKHERKDTVKNAEETGWFVWNMATYDLREAVNLSSKA
                     LPPEEDEFEFAGVTKEACIEAPGYRVKESPVHFECEYVQTIRIPTGDPVSTVDIVIGRV
                     AQVHIDDKVIMENGKLNIKSIRPIARLGYYDYTVVDQIFEMKAPAATKEELAGLEGRNF
                     DNTTE"
     misc_feature    complement(16520..16535)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            complement(16735..17283)
                     /gene="hxlB"
                     /locus_tag="JC281_RS10860"
                     /old_locus_tag="JC281_10860"
     CDS             complement(16735..17283)
                     /EC_number="5.3.1.27"
                     /GO_function="GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="hxlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169036.1"
                     /locus_tag="JC281_RS10860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10860"
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="WP_070407649.1"
                     /transl_table=11
                     /translation="MAIQQQLERIRREIAQTLSQVDDQAIAGFEQVVSDAEAVFVTGKG
                     RSGFVANGFAMRLNQLGKKAHVVGEATTPSIQKGDVLIVISGSGSTTHLKLLADKAHEV
                     GATIALVTTATDSKIGELANVTLILPAGTKYQAEGSEQPLGSLFEQSAQLMLDGVVLDF
                     MTAWDVDETTMQNNHANLE"
     misc_feature    17239..17249
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(17285..17923)
                     /gene="hxlA"
                     /locus_tag="JC281_RS10865"
                     /old_locus_tag="JC281_10865"
     CDS             complement(17285..17923)
                     /EC_number="4.1.2.43"
                     /GO_function="GO:0043801 - hexulose-6-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019647 - formaldehyde assimilation via
                     ribulose monophosphate cycle [Evidence IEA]"
                     /codon_start=1
                     /gene="hxlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834869.1"
                     /locus_tag="JC281_RS10865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10865"
                     /product="3-hexulose-6-phosphate synthase"
                     /protein_id="WP_014614722.1"
                     /transl_table=11
                     /translation="MELQLAIDLLNKEDAAELAKKVTDYVDIVEIGTPIVINEGLPAVQ
                     HLKENVKDEDVKVLADLKIMDAADYEVSQAVKFGADVVTILGVAEDASIKNAVEEAHKH
                     GKELLVDLIAVQDLEKRAKEIDALGADYIAVHIGYDLQAEGQSPLESLRKVKSVIKNAK
                     IAVAGGIKPETVKEVADEGPDLIIVGGGIANADDPREAAKQIREAIEGK"
     gene            complement(18021..18755)
                     /gene="nagB"
                     /locus_tag="JC281_RS10870"
                     /old_locus_tag="JC281_10870"
     CDS             complement(18021..18755)
                     /EC_number="3.5.99.6"
                     /GO_function="GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0006046 - N-acetylglucosamine catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614723.1"
                     /locus_tag="JC281_RS10870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10870"
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_014614723.1"
                     /transl_table=11
                     /translation="MKIINLGREANASFYVASELFKQMLYQKDSRLGLATGGTMVKVYD
                     YLVELLQKNQLDVSQVETFNLDEYVGLASDHEESYCQYMKHVLFGAYPHFTAENIHVPN
                     GEASDIEAESQRYEALLEEGGPLDIQILGIGQNGHIGFNEPGTPFESLTHCVDLTESTI
                     KANSRYFDSIDDVPKQAISMGLSSIMKAKRIILLAFGEQKREAIRHLMSQEVTTDVPAT
                     ILHRHPHVEVYVDDAAMPEIDN"
     gene            complement(18761..19435)
                     /locus_tag="JC281_RS10875"
                     /old_locus_tag="JC281_10875"
     CDS             complement(18761..19435)
                     /EC_number="5.1.3.9"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728633.1"
                     /locus_tag="JC281_RS10875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10875"
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="WP_014614724.1"
                     /transl_table=11
                     /translation="MNLTQGLIVSCQALPDEPLHSSFIMGKMALAAKQGGAVGIRANTK
                     ADILAIKKEVDLPVIGIVKRDYDNSSVFITATQKEVDELIESGCEVIAMDATLRERPAE
                     DLETLVQYIRKAAPDVEIMADIATVEEAQNAERLGFDYIGTTLHGYTEQTTGQVLYAND
                     FAFLKDVLANVSQKVIAEGNVITPEMLKTVMDLGVYAAVVGGAITRPRDITKRFVKMIE
                     EE"
     gene            complement(19436..20974)
                     /locus_tag="JC281_RS10880"
                     /old_locus_tag="JC281_10880"
     CDS             complement(19436..20974)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166666.1"
                     /locus_tag="JC281_RS10880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_10880"
                     /product="PTS transporter subunit EIIC"
                     /protein_id="WP_014614725.1"
                     /transl_table=11
                     /translation="MNTLFDKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTIEAYP
                     FLNIPLLQHLFILMRTAGSIVFQNLSVLFAIGVAVGLARADKGTAGLAAMLGFLIMNAT
                     MSGLLTITEQVAAPDQLAKAGQGMVLGIQTVETGVFGGIIVGIITAMLHNQYYKITLPQ
                     FLGFFGGSRFIPIVTAFASIVLGLVMFFIWPLFQHAIMGAGQIVKQTGVIGTFLYGFIL
                     RMLGPFGLHHIFYLPFWQTALGGSLELNGKLIQGTQNIFFAQLGDPATAHYYEGVSRYM
                     SGRFITMMFGLLGAALAIYHTAKPERKKVVGGLMLSAALTSFLTGITEPLEFSFLFVAP
                     LLYVVHALLDGLAFMMADIFNITVGQTFSGGFIDFILFGVLQGQAKTNYLWIIPIGLVW
                     FALYYVIFRMLIQMFNFKTPGREDETTQQSVQTNERATTIIQGLGGHENIEIVDCCATR
                     LRVTLKDTQKVNESLIQGTEPKGIITKGNGVQIVYGPHVSTIKNEVEEQLEGSH"
     misc_feature    21050..21064
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.65"
                     /tool="antismash"
     misc_feature    21102..21116
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.85"
                     /tool="antismash"
ORIGIN
        1 gtgattaaag gtggtaaagc gttagatcaa gataaatcat acgacttata ctatgatggc
       61 aacaagttct accagttaac aacggacatg ttccaacaaa gttacaacca cggggcaggc
      121 tgtacatttg cggcagcgac aacagccaac ttagcgaatg gacaaacacc aaaagaagcc
      181 gtgattaatg cgaaagcgtt cgtagcttct gccattaaaa acggttggaa aatgaacgat
      241 tatgttggcc ctgtcgatca cggtgcatca aatcgtgttg aacaaattga agttgaagtg
      301 actgaaattt aatttccttc tcactcagat tcaaactccg tatttaaata aacatggcta
      361 aaaccttgat gtattatatt gttgagctcc gttatctcgt tcacattatg atacatcaag
      421 gttatttttt tgagattggg caattccctt gctctcctag gacgctttta cttctatcac
      481 gattttcagt tgttcatcta ttcccgacac ttgaatttgc atgttgtcac gctgccaagt
      541 gacctgttca tcaaccccaa tagtattttt ataacgtacc gctatcggtt caactccagc
      601 ctcgacacat acatattgga cgacgagttg gcctgggaca atatccgtat gtatcggatt
      661 cgtgtcattc accagtgcta aatagtgctg cacgtcttct gttgaaaaac acatcatgac
      721 accctccgac tgacaaaagt ttgtatgatt cgacaatggc atgtatcagc ttgatcgaat
      781 gataatgcca tttgataacg ttgaaatgac ttgatttgtt ggacttttaa tacggccatt
      841 gtcacttgat aatgctcgcc tacttttaaa gggtaatgtg tttcaatttc tgtagctacg
      901 agtcgaattg ctgtttcttt aaatggtcga aatagcgaaa aaagtggcca tacgcgtgca
      961 gtcattaata aagggacggt ggtcgtctgt ggcatattaa aaaattgttg ataacgctgg
     1021 actgcacttt tgtcgaaaca gtaagcttta acttcacggt cgccaacgtt caaaaagtgc
     1081 tgcattgccc atgccccctc caatgcccat tgtcgcaatg gtactttgtg catctttcat
     1141 gtaaaacaga cgggtcacta aaatcgcacc actcgcacta tacggatgac cgatcgcaat
     1201 cgcaccaccg taacgattca attgcgcctc ttgaatgttc aacgcacgtg cagacgctaa
     1261 cacttgcgcg ctaaaagctt cattcaattc tacggcatca atttggtcta tcgtccgttg
     1321 ttgtcgttct aaaatgcgct gcactgcggg tacaggaccg atgcctaata catgtggatc
     1381 caccccttca accgcataat ccataaacat cagaccttcc gacataccga gttcgcgtgc
     1441 tttttgttca gacatgacga caactagaca ggcgccgtcg tgtttgagac aacaattacc
     1501 gactgtcact gtcccacctt cacgtaatgg ctttaaccgt gcaatacgct catactgaag
     1561 atgcggctta acactttcat cttgtatcat ttgctgacct ttcactatta gtggcaatat
     1621 ttcagctgac atcgcacctg tcgcaatcgc tttacttgca cgatgatggc tttgaaccgc
     1681 aaaacgatct tggtcttcac gtgacacatc atactgtttt gccacgttgt ctgccgcttc
     1741 aatcatagtc ggatcttgac ctactggcgc aaatggcgca cgctcataaa atgtcggagg
     1801 tgtcgttgga tacagtgatg tcggcttttc cattttccaa ggtgcacgac tcgtactttc
     1861 gacaccccct gcaatataaa agtctcctgc accgctttca acgagtcgac tcgccaaatg
     1921 aattgcttca aggcccgaac cgcattgacg atcaaccgtg agacctggaa cagacacatc
     1981 tatccctgcc tcgagcaaac tttttcgcgc aatattgccc cctttaccga caatattacc
     2041 gagaatgacg tcatctaaat cattgagtga acaagataat gtcgcttcaa aatgttcgaa
     2101 taacggtttc agtagatgct ccggctccca tttttgaagt tgaccgccat acacgccaat
     2161 tggtgtccgt tttgctgcaa caatgactgc tttcgtcatt gataatcacc cctttcatag
     2221 caagtttgtg ccatttttct cgaaactttc ccactctcag tatatggtaa tgttgcgacg
     2281 taaataaatt ttgacggtat ttcatatctc gatacacgtg atgacaacca gtgccgtacc
     2341 gcttgaatgt ccaactgttc cggacccgta taaagggcaa tcgctaactc acctagctta
     2401 tcatgtggaa gtcgtacaat gaccacatct acaatttcag gcctttgctt gaggtgttgt
     2461 tcaatcacag caggatacac attcttccca ccaataatca agcggtcttg tacacgccct
     2521 tttaaataca gcacatcatt ctcgatacgg gcgtaatcac ctgtcgctat ccattcatta
     2581 acggaggcct caccgagata acctgaaaat gtcatcgggc ttttcacaaa caattgtcct
     2641 attccggcat catctcgttc acgtaatgtc actgtcacat ttggaaatag acgccccaca
     2701 gaatcgagtg gtgcagtttg attacgattg acactaataa agctcgcttc cgacgtgccg
     2761 aaaaactcat caatcgcgct ttcaggaaat atctttttga gttgtgtgtg acgactggcg
     2821 ggcaatttgt ctccagaaat aaaaatgtga cgtacccact gtgactgttc tcctaaatgg
     2881 atcccatcgt acaccattgt aggtacgata aacaatgcac acgtttgttg aagttctgca
     2941 acatatacca aactttttgc catatcatag cgatcttgcc cgataaacgt tttgccattc
     3001 cataacgcat aaatcagcac atacaacgtt aacgaatgag catacggacc gagtgccata
     3061 tacgtctgtg tagaggcatc aagcaacgta tcattcactt caaatgaagc aatccatgac
     3121 ggtaaatccc tcataaaccc tttcggtaaa cctgtcgtac ctgacgtaaa cccaatatgt
     3181 aagcattgcg gaatcattgg tgctttatgt gcgggttcgt gtgaagtaga tgtcaatcct
     3241 tcatctcccc atacataagg catacggtgt aacttaatga gcgcatcccg ttgttccgtt
     3301 gaccattgcg gtccgagcac acacggcaca ccttgacgta tgagggccgc taaataagct
     3361 acgataaagt ccaacgtttg ggtatgcgtc aacattacat tttgatgcga tatattcgtg
     3421 ggcaatgctt cactttcctt ttgcacatct cgccacaacg attcataggt gagcgtcaca
     3481 tcgtccatcc taatcgcaat atgttccggt ctttctacgg catatgtttc aagtcgcttt
     3541 aacaattcca aacttcatca cactactttt acaatttttc tttattttaa catagcgtgc
     3601 actttccaca tatgtggatt tcattttgtc cctccatctt tcatatgtgg tcatcatgca
     3661 aaatttaatg tgatgccaac tcatccatat tgatgcattt ccatgtgaaa aggccgggtc
     3721 atcgtgaaat gcccagcctt aaaataatac agttgttata aataatattt gtcaataact
     3781 tttaaatcat ctgtcaattc gtaaatcagt ggcgcacctg ttttaatttc atagccgacg
     3841 atatcttcat ctgatacgcc ttctaaatat ttaatcaaag cacgtaatga gtttccatgg
     3901 gccgctacaa gtactgtttt atcagctaat aattcttgag aaatttggtc gttccaatat
     3961 gggatgacac gcaccaaagt atctttcaaa ctttcagatt caggcatcac gcgtctatct
     4021 aataattcgt atttgcgatc ttttaaatag cgctcgcgtt gtgcttcatc ttgtgctggc
     4081 ggaggtgtat cgtaagaacg tctccaaata tggacttgtt cttcaccaaa ttgctgacgt
     4141 gcttcatctt tatttaatcc ttgtaaacca ccgtaatgac gttcatttaa acgccacgat
     4201 ttaacaacgg gtacgtagag ttgatcagac tcatttaata aatgaaacgt ggtcttaatc
     4261 gcacgcttta ataacgaggt aaatgcaata tcaatctgaa tttcttgttc tttcaatttt
     4321 tttcctgatg tgatggcttc gttgtgacct tgttcggata aatcgacgtc tgcccatcct
     4381 gtaaataagt tttcagcatt ccagacgctt tgtccgtgtc tacataaaat aagttttggc
     4441 atgttttacc ttctttctat atcgtgaacg ccagtgtcgc aacatttgtt gatcaaaaaa
     4501 gacgttcacg tactcatatt gtaccaacaa atgcgcttac tttattttat aaattgatta
     4561 taacaagttt tttatgcttt ttcatgattc caacatgata aaatttgaat atattaagtc
     4621 atttgctcga aatcggatat aaaacttttc ggtcatctga attgatatat ttcaatcaag
     4681 ccctccccat tgatatccat tttttaaatt ttacaattgc catcctgggc ttgctttcct
     4741 aggggacttg cctcaactaa attcggcagg attgaagtac acatttgtaa gaagccgaat
     4801 tggattttcg gctgcgtctg atccctcagg agtctccccc attttagcaa ttgaatatcg
     4861 aatattgtga atcaatgatg gtcaaacatt tgattatgaa gagaacgaaa attatcaaaa
     4921 attttaatcc tgtatcatct gacttgattt tatggttcaa tataactgtt ttcaattttc
     4981 atagcaaagc agaaaaaata gtaatgttcc attctcatag atatccccct gttttcaaaa
     5041 agaatagagg cctatctccc tattcttcat cacgtaccaa ttgaatggtt ttagaagcga
     5101 ttgtttctac aaaatgtgca ttatgatcaa tcccaatcat ggtcggtcgc gcattggcca
     5161 acatgtcaat cagttggtcc acaacataaa agtctaagta attagtcact tcatcccaca
     5221 tcaacaaact actttgctga attagcgaat gggcaatcaa cacttttttc ttttcaccat
     5281 cactccagcc ttccgtttgt cgtgccgtga attttttctt ttcgactcct aattgataaa
     5341 gtaaatgtag aaacttctcc ttttgaggtt gtggcaaagt ttgaaaccat tgattgtgat
     5401 catcttgata cacatatttt tgatcgacca ctgacgtctt ttcaggtaaa tgaatgtcat
     5461 actctcccac aatatcatac tgttccggat gttgtataaa gttgaataac attgatttcc
     5521 ccacaccatt ttcctacatt ttttattttc taaattatat aatcatgtct taactcaata
     5581 tttgaacaga ggttgtttga ttgagacatg atatatacga aagagtgtta ttttacaatt
     5641 aaaagaataa aaccaaatga tgctgaactg ggtagacatt atcattgcga ccccagaaca
     5701 gttaaaaaat attacgaagc tggaaaagaa aatgagttag aaaaaaagca aggaaaacga
     5761 gagcaacaaa attagaacct tataaaacgc tcatagacga aaaattagag ttaggttgta
     5821 tggctatggc gattaataaa tagatttcta aaaaaggata tgaaggcaag tatacgattc
     5881 tgagagaata ttgtaagaat aagaaagaaa aggaatttaa aaagcaatta tacgggtaga
     5941 aacacacccc ggtatagctg ctcaagtaga ctggaaagaa gatatggtca tgcgtgataa
     6001 atttggcaaa cgttatcaat tcaatatctt tctttacgtt tatataatat atggttctta
     6061 ggcaataggg gtaccgataa gacccatcta gcaatatcgc taggcataga agtctgtaaa
     6121 caaaatatca aaactcgatt ctatactttt aaagaattaa ttgaactctt aaccacttca
     6181 gaggagaaag gactaaccaa taaaacttta aaacaattaa acagaattga actacttatt
     6241 attgatgaga taggctatac acccatttca aaagaacagg cagacctctt ctatcaattg
     6301 atgtcactaa gatatgaaat gaaatccacg atcataacga cgaatatccc cttttctagt
     6361 tggggagatt aatttaggaa caaaatagcg tcagcaacca ttattgataa actcattcat
     6421 cattcaaaaa tatttaaaat tacagaggct tcctaacgac ttaaagtcta taaaagtaaa
     6481 aaagtttaaa tatatgtcat cgttcttaaa ccgctaaaaa ccgacatttt caaaccgcta
     6541 ttgacactgt tgacgaacaa aaaagaactt tatatttttc agcaagaaca tatgacgaat
     6601 cataaagtat cgatgttctt actactagta ctgtaacaaa cttattccat caagataaca
     6661 agcatactcg gcaaaatcga gtaggagatt agtcattaat tgactattcg tcctctcaca
     6721 ccaccgagcg tacggttccg tactcggcgg ttcaatatct tgcgtaagcc aactctgcaa
     6781 gctgggctaa cggtattaat ccccactttt agagttattt tgttgtaagt gcacgatgaa
     6841 cctcgtgcgt attcgataat cgccaatatt tttttgcgag actgtgcgat tttcattgca
     6901 cttctatggt caagcccata ttgacgcaac atcttatatt tagttctaac tcttttccac
     6961 cgtttaagaa tgagttgtct aagccggcgg ttcaaccaag attgcgtggt ttcaataaat
     7021 cctctgataa aacctctacc aaagtcattt atccaacctc gcgtcacttg gttaatttca
     7081 atgataatgt ctttaaaggt accgggtcta tttcgtttcg ttattttcct taaggtgcgt
     7141 attaaatttc tttttgcttc catagtcggt ctgaaacgac aaaccccatt gaccttggtt
     7201 attagacaac tcaagaactt taaacgtgtg actgctccta ctttactttt ctcttcattg
     7261 acaaccaact tcaattgctt ttcaatgaat ttcgttacac tcgtcatcac gcgttcacct
     7321 gcacgttttg tgcgtacaaa gatgacaaag tcatcggcat accgtacaaa acgatgtccg
     7381 cgcttttcga gttctttatc cagttcatgt agatagatat tacatagtaa gggagagata
     7441 acgccccctt gtggtgcacc tatctttctt tctgtgactt cgccagatag gtcaatggca
     7501 ccgacttgta aacttctacg gataaatgtg gaaattgact tatcttgaac atggcgttcg
     7561 aacaaataca tgagcttatc atgattcaac atgtcaaagc actgtttcaa atcacaatcc
     7621 acagctattt tatagccttc ttcgtagtag tcagcacatt gcttaagtgc tgttcctgtg
     7681 ctacgatgag gtctgaaacc atggctatga tttgagaatg ttcggtcgat gcctggttca
     7741 atcacttgtc taatggcttg ttgtatgact ctgtctctag cgacaggaat accaagcaca
     7801 cgcattttcc cgtttggttt gggaatttga acttttcgaa ctgcttgagg ttgatatgaa
     7861 ccatcaagca gttttttcgt tatctgtgaa aagtactgcg caaagtgagc atggagttca
     7921 ctgactttca tgccgtcaat tccaggagcg cctttatttt tcttaacctt tttgatagcc
     7981 ttttctatat tttcaggtct tacaacaagc tccatcagtg atggagactt acgatacatt
     8041 tctttcattt cacctaagat ttactgtaca cacttatgta ttctttttcg ttccactact
     8101 tatccttcca taagttgccg gttaacaccg tattctgtac gtcgtaaatc tataacctcc
     8161 aatctttact ttgtattgaa tattgttcag tccttcggta cattttccct actatgactt
     8221 ctgctgactt ctcatccttc gttgttacta cggtagagat accgttgatg agacctcccc
     8281 gggtaaggtg taacctcttt ccactcatgt caccgcatca tttactatat agaactcggg
     8341 tagtatcgga cttcatcttg tatagcagat tcattcattc tacatagcct tagtatgatg
     8401 tttctgttcg tcagtacgag tgtttgcgtc cgacttcctt cagattccac ttcgcaatgg
     8461 acacctttgt ctttcactaa cagttcctac taccaagcct gtaacgaact tacaccgtca
     8521 agatgttacc catgccgggc gcacttaaaa aagcgatgta ctttcactca tgaagtaaat
     8581 cgctttttga gattatgtaa ttatagacca aaagtttata accctagttt tagccatctc
     8641 tttttagata atcccaatac aataaaatta acaataaata caaaagtgaa aaatagtgcg
     8701 atagttaata catcatggag attaattgtc ggaatctcac cattaagcac tttttctaca
     8761 gatacataca tcgaattact agcttcaaat ggtgctaaaa acccaaacat ttctttattg
     8821 atagctacca aaatgataga agcaatccaa taaacaatac ttaatccaat acttattaat
     8881 acatttggag aaacaatact tatagtacct actactaata tatattgcag aactacaagt
     8941 aaaaacataa ttattaagaa aaaataatgg gagaagtctg aaaaaaccat agagataatg
     9001 gtaataccta caactataat cgctaaagat tctaaaaata atatggacgc ttttttatag
     9061 aaaaaggaat atatattttc ttttatgagt ttgtagaaca acaaactttt atttgaatat
     9121 tccttgttta taaaataaga aataataaac gagaatagta aaaatccgaa ttcggttaaa
     9181 accgtgtagg cgctaaaaaa atatttaggg taatccaaat ttgttacttt atctatgcct
     9241 actggtaaaa aatagcctaa taaaaatgaa aatacaaata gtatacttaa agtcattaaa
     9301 attttgtttg aaatactttt tttaaactct aacttcaaaa tttacacctc ttttataaat
     9361 ttatataatc atcaattaat tgatctttag aattatactc ttcaatcttt tgatttttaa
     9421 atataaaata tttacctggt aagctactaa gatctgataa atcatgagta atatttacta
     9481 cagttttaga tggatgttct tttataaaat cattcaagaa aatataaatt tcattaactg
     9541 tcttcttatc taaagcatta gtgatttcat ctagtataat aagtgagttg tcttctaata
     9601 aaaaacttaa aaatttaagc ttttgctttt gtccatcact tagatttttt atcaacactt
     9661 tagaaggaat gtcattaatg ttaagaattt cactaatttt agaaaatgtc ttttgagcac
     9721 ctggaaacct tgctttcaat aaattcaata gaaattcttt tgttatatca tgaggaacat
     9781 tagatgaact tgaaattaaa gtaacacctt tattaattga ctttggaata ctaccactat
     9841 tatttaatat aaagtctttt gctaactgtg attttcccac tccatttttc cctacaatat
     9901 ggttaatttc tccagagtag aattttaagt tacaattatt aattaattcc ttccctttaa
     9961 ccttcaaaga ataatcaacg atttccaatg tttacaactc ctatatacta atatttttaa
    10021 tccaataaaa aacccaatga attatagtat ttaaagcaat aactacccca atagtttgaa
    10081 aaattaaaat taaccaatgg tttttagtga aattattaaa ttcatctaag gataatgcaa
    10141 ccatcataat tttgtatcca tctgaattca atatggggac caaattccat aataatgttg
    10201 aagaaaaaaa catatatgca accgttaaag cataactatc aattattaat atattcatta
    10261 attgaagtaa attaatcgat ataatattaa taaacaatcc gaatgaatga acaattattt
    10321 tgtcaatttt agataacatg tatgtctcat tcatttgaac atagaaggac ggaaaaacat
    10381 aaaagtttaa cctaaatcca aatttatcta ttttacgacc gaagaatttt aatgaataaa
    10441 tatgccctaa ttcatgtaag aaaacactaa ccaaaaaata taaaatcaaa accactgtaa
    10501 cttcattttc aaaaataata atgatatttt tttgcaaata taatgtgtaa agaatatttg
    10561 ttataattac aataacacta agtaacatat atgtaaaaaa taaaaaacaa tttacttttt
    10621 caggataact gttgaatttt tttaacattt tttcgtcaat agaattcata ttattcctat
    10681 aataagaatt agttttttta tcctttataa acacatggtt ctgtattaat atctcatatt
    10741 ccttatcttc atacttcaat ggtttcataa tagtaggctt ccataaatgg tttaaaaaat
    10801 ttaatttttt cttcagtgct aaataagcta ccacatatgc tacaaacaga tgggaaatct
    10861 gttgggatat caaattgatg taacatattc tcttctctta gtatatctaa aaaccaatta
    10921 aatccttctt ttctaataat atacaataat aaattagagt tcagcttttc tacagttctt
    10981 gttaaagttt ggtttttatt ttctctaaga gtaatcggag tttcaaaaat agctggtgag
    11041 caacaaggat aaatttctcc atcgtggtga tagactattt caaagcctgg acaataaagc
    11101 acttctctat ctttatttat attgtaaaaa ttatgtatat tttcttttga tattttgtct
    11161 ttggcagcac ccacagaaat catcggaaat ttagtaattt tcgcccccaa tattgaactc
    11221 cctaactccc ttaaaatatt atctgacatt ttatcttttg tgactgccat attaagtgac
    11281 acttgtattt cggggtattt cattctatat tcaaatatat tttttatact tttgagttta
    11341 acaaatggtg aatgatattc atcataactt atggttaaag ctactacatt atatttgtaa
    11401 aaatctgaaa agtatttttc caaaagcttt ctgctattcc cccaaaaacc attagaaata
    11461 agagttactt ttttattata gttttttgta attttcagca gttcttctaa gaattcataa
    11521 tttaaaaata tttctccacc tgtaaaagaa ataacctcca cattagaatc tttagcaaat
    11581 tctaatacag tttctctaat ataaaaatct tccattttaa ttgtagattt tggtgaacaa
    11641 gaaaaacaac aatgatcaca agtagcatta cactttgagg ttagatttat agagacactt
    11701 ttatcataca taattaattc tccccctaaa aaactaaacg gagagatagc tctccgctta
    11761 tttgaattaa tgcccactgc ccacaatcca acgatttgat tgtgatttaa caaagtacca
    11821 taaatcatta actttagcta atttttcaga atcattaact agttttttga attccaaatc
    11881 tttcatcgta ttctctttag tacttttgta actgttaatt tcttttttca tttccactca
    11941 cctcccattt aaatctatct ctattttact ccgcttattt gtttttttca attaaattaa
    12001 agatattttt taaaaaattc aaaatgtttt caaatataag tcccagagta cattagcttt
    12061 aattttaaaa atcaaaaatt gtttgaatgg tacaatacaa ttgagattcc actagaactc
    12121 gttaattgat aaacttacaa taaaaacaag ttgttcaagt taaagtgccc cacatgtcaa
    12181 ggacacttta aaagaaggta attaacttaa taattaactc ccactatgat tgacatagga
    12241 ggagttaagg caatgtgagc ctatactcaa aactaagagt atggactttt gctttaaaat
    12301 tataactatg gaaattatga gttttagtga gttttgtatg gcacatgaga atagaagggt
    12361 acctaactgg atgattcgag attttaatgg tttgaatgat acaaatcttt gggattacta
    12421 tgagtcatat aattccctta gattgatatg tttatctgaa agttacttac atgatgccct
    12481 gaagtttgtg ttgaaggata actctaatga ccttatttat gacttctatg tctttctaat
    12541 gtttgatgaa agtgtgtgtg acattgattc aattgtatta tccgtagaaa tgaataaact
    12601 cattattcaa tatcacacta aatttgaggc tgagtttaac ttcgatagtg agatattggg
    12661 accgccgggg gattttgata ttgaatcaat ggataatctc ccgttttaat gtacgtctca
    12721 aattgatttg gagataactt tgccagccct atttgaaacc tatcaatgtt gtagtaatcg
    12781 atataatcat ctattagtcg aaccagatct tgaaaaacat gaatgccttt gatgcttttg
    12841 atttcatctt tcatatgacc aaaaaacgat tcttgaggtg cattatccca acagttccct
    12901 ttttctagac atcgattgtt ttaaaccact tgcgctaact aattcttgaa atgatgtaca
    12961 tgtatagtga attccttggt ctgagtggat aattaatttt ttattttttg atatatggtg
    13021 tttcttcatg agttttgaaa ccgtatttaa tacaatgtct actttcagac tctcacttaa
    13081 ttcatacgaa agtatctgat ttgtgtaagc atcttttata gtagataggt atgcgatttt
    13141 gccttttcca taatataaat atgtaatatc cgtaagaaga attgtttttg gaccacccat
    13201 tttgaaatga cggttaacta aattatcttt aacacgttgt tcattagaat acttcattgc
    13261 ttgtttatgc agatttgact ttcttattgg gcatactaaa ttaaactttt tcataagtct
    13321 aataatcttt tttcgattca tgacaacgcc ttggtgtaac agggtcatat gaatacttct
    13381 tgaaccttta gagtaccctc gcttattaaa cgctgctaga atcaattcaa aatctttttc
    13441 atcctttttc tcacgctcaa tgcgcttagc gtttctcttt ttccacgcat aaaaacctca
    13501 tcttgaaact tggacaatct cacacagcca agatatatta agtaagttat tgtctcttga
    13561 aatcaagcta tctatgagtt cgaatttttc ttgcgcatag cttttgaagc acggcgattg
    13621 atagaattcg ttttttttag cgcctctatt tgttgattct gaagttggat tttatgtttt
    13681 aaatagttgt tttcttcttc tagtgtcatt tctgataatc taggtcttcc agaattttct
    13741 ttcctcgtgt cttgtaatcc ttcaggtcgg tctttcatca taagtacgcg ttctctaaag
    13801 ttactcattc gtcttcctaa gattttcgta ttaaacccag cctctttaaa gatttgtgaa
    13861 ggcgtctttc cattttcata ttcttcaaca aaatgttctc taaattcttc tgtatatgtg
    13921 attgctttag gtgatacatt aagcacgtat ttgttggatt ttaaatctgc aatctcatct
    13981 tcagtaaata aacgtttact catcacttta cacctcttag tcaatgaagt agttactaaa
    14041 attatacatt aaaataaccc tatagactga ctctttttta gtgtctcatc tataggggcc
    14101 attttactgc tactactaca atttcctgtg tcactctatc gctgtctgac ttcattttga
    14161 tgcgctagca aagtataggt cgtttcaatg tacggaatat gaagttgatg cttttgacct
    14221 tgtctataaa tataaccttg aattgcttca acttctgtca cacgctcatt catcgtatca
    14281 taatacatgc tcgtcgcact ttcatcagag aaaatacgat acgccgcaat gacatcatct
    14341 acaaatgaat cttcgtatgt aatcccttct gcgttagcga cttgcaaacc ttctttaagc
    14401 aagtttttac ataattccag catactatcg tcttttaaca gacgcgctgt gtctcgactc
    14461 aatgcagtta aagtgttcat gccgaggttg aaaatcaatt taaaccaaat cgccttctca
    14521 atattgtctt caagttctaa cgtgagcgct gtcgttgaaa tgaccgcttt caattgttca
    14581 gtaaacgcat cttgcttcaa ctgaatgcga taatctttgt catgtctcac tttatcctcc
    14641 tgcttttcac cgctaatata tacgaccgct tgatacgcat catagccctc taattttgga
    14701 agtaagccgc taccattttg tgctaaaatc actttcgatt gcgcgtgcgt gattgtcttc
    14761 agttgtggta aaatcgtatc aatttgatgg gtcttcaccg caataaacac gacatcgaac
    14821 gtcgtcgtta cagatgacaa tgctttgaca gggatacttt tgcgttctcc tgtgtcacgc
    14881 tcttcaaatg tcatgacttt atcttgtctc cctaacaatg ttacatctag cgtatccaat
    14941 accgaagcga tcgctgttcc taccgcaccg ggtccaatga tggctatttt catctctatc
    15001 atcctttcaa tcgcaaagtc tcaatgcatt tctcatgctt ttatacataa ctcaatatat
    15061 tcttttttta tttataagta aagcgagttg attgtatatt taaatacaaa aaagaccggg
    15121 acatgatacg ttttcccagt cttccttcaa tgtaaaaatt ttagtgcttt tttcaccaca
    15181 gaaactgaat agcatacttt tctgctacac gctttctttc gagttataac aacgattaca
    15241 ctatatctgt taaaatgtcg cttaagatac accttgaagt tcagatactt tggttttaat
    15301 cataacttca tcgccctttg ttaacttttt tgttacaatg gctgcatttc aattcaactc
    15361 aaaacattga tgtgctgcta tgaaaattta gaataaaact taaacattcc taagattttt
    15421 cattattttg tttaaatata cctgtaagca tgcaacgaca tcacttaatg gtatcggagg
    15481 cacgcttatt cagttgtatt atcgaaatta cgtccttcaa gtcctgcaag ttcttctttt
    15541 gttgcggctg gcgctttcat ttcaaaaatt tgatccacta ctgtgtaatc ataataaccg
    15601 agacgtgcaa tcgggcgaat agacttaata tttaacttac cgttctccat aatcactttg
    15661 tcatcgatgt gaacttgcgc gacacgaccg ataacaatgt ccactgtaga cacaggatct
    15721 cccgttggaa tacgaatggt ttgtacgtac tcgcattcaa aatggaccgg tgattcttta
    15781 acacgatatc cgggtgcttc aatacatgct tctttcgtga cacctgcaaa ctcaaactcg
    15841 tcttcttcag gtggtaatgc cttagacgac aagttcaccg cttctcgcaa atcatacgtg
    15901 gccatattcc aaacaaacca acctgtctct tctgcatttt ttactgtatc tttacgttca
    15961 tgcttgccga gtactgattg attcgctgca aacatgacca tgggtggatc ccaagttaag
    16021 ttttgatact gactataagg tgccagatta tctttgccat cttttgaaac cgttgaaatc
    16081 caaccaatcg gacgcgggac tgtactactc ttaaatggat cgtatggcaa accgtgactt
    16141 ctaacccctt gttttggtga atactccatc ctattacctc cttcatcatt gcctttactt
    16201 taatctaaca aatggtgtca tccgttgcta atacatgttt tctatttaat tattaggcag
    16261 ttctattaac agaatctgat gtacgttgaa cagaactgtt ccctatctcc acttctattt
    16321 caagtaaaca tactatttga attttaaata acaggataaa tacttctctt gttctataca
    16381 taataaaatt atctgctttc tttatttaac aatactcccc tcaaagcagt tgtccgatta
    16441 agtataaaca attcagtata tttaatttac ttttttattt tttttaggta ctatgaaaaa
    16501 aaggaggaat tgatatgcat gtgattatcc ttacactttg cttactccca ttggttttgg
    16561 ttaatttgta cttttatttt aagaaaaaga aagaaaaatc ctagttataa cgatttttta
    16621 agttcaaaaa ttttaaagaa acatactaag atgagctgtt aaaaaagcta gttcctacaa
    16681 ccgtattgta gaaactagct cttttttaca tatcatacga tttttacaat tgtactattc
    16741 taaattcgca tgattatttt gcatcgttgt ctcatcgaca tcccatgcgg tcatgaagtc
    16801 taacacgaca ccatctaaca tcaactgtgc actttgttca aacaagctgc cgagtggttg
    16861 ttcagaacct tcagcctgat atttcgtgcc agctggtagg atgagtgtca cgtttgccaa
    16921 ttcaccgatt ttagaatccg ttgctgtcgt aaccaatgca atcgtcgcgc cgacttcatg
    16981 cgctttatcg gctaacagtt ttaaatgtgt tgtcgaacct gagcccgaaa tgacaatgag
    17041 cacatcccct ttttgaatgg acggtgtcgt cgcttctcca acgacgtgcg cctttttacc
    17101 aagttgattc aaacgcatcg caaaaccatt cgcgacgaat cctgaacggc ctttacctgt
    17161 cacgaatacc gcttctgcat cagatacaac ttgttcgaat cccgctatcg cttggtcatc
    17221 cacttgtgat aacgtctgtg caatctcacg gcgaatccgt tcaagctgtt gttgaatggc
    17281 catgttattt accttcaatc gcttctcgga tttgtttagc cgcttcacgt ggatcgtcag
    17341 catttgcgat accgccaccg acgataatta aatccgggcc ttcatccgca acttctttaa
    17401 ctgtttctgg tttaattcca ccagcgacag caatttttgc atttttgatg accgacttta
    17461 cttttcttaa gctttctaaa ggtgattgcc cttcagcttg taagtcataa ccgatatgca
    17521 cggcgatata gtctgcacct aatgcgtcaa tttctttcgc acgtttttct aaatcttgaa
    17581 cagcaattaa gtcgacaagt aattctttac catgtttgtg cgcttcttcc accgcatttt
    17641 tgatggatgc atcttcagct acacctaaaa ttgtgacaac atccgcgcca aatttcactg
    17701 cttggctcac ttcatagtct gccgcgtcca taatttttaa gtcagctaat actttgacat
    17761 cttcatcttt cacgttctct tttaaatgtt gcacagctgg taagccttca ttaatgacga
    17821 taggtgttcc gatttcaaca atatcgacat agtccgttac ttttttcgca agttctgctg
    17881 catcttcttt atttaataaa tcaatggcta attgtaattc catgatttca tcaatcctcc
    17941 gtcatgtttt gtctcttaca actcgtgcta taccctttag aaaagagatt aaacatgtcg
    18001 gatttatagt tcaacgcgac ttaattgtca atttcaggca ttgctgcatc atccacatac
    18061 acttctacat ggggatgacg atgtaaaatc gtcgctggca catccgtagt cacttcttgg
    18121 ctcattaaat gacgaatcgc ttcacgtttt tgctcaccaa acgctaacaa aatgatacgt
    18181 ttcgctttca taatagaact taatcccatt gaaatggctt gttttggtac atcatcaatc
    18241 gaatcaaaat aacgactatt cgctttaatt gtgctttcag ttaaatcgac acaatgcgtt
    18301 aaactttcaa acggtgtccc tggttcatta aaaccaatat gaccgttttg accgatgcct
    18361 aaaatttgaa tatctaacgg accgccttct tctaatagcg cttcataacg ttgagattcc
    18421 gcttcaatat ctgatgcttc accatttggc acgtgaatat tttcagcagt aaaatgagga
    18481 tacgcgccaa ataaaacatg tttcatatat tggcaatagc tttcctcatg atctgacgct
    18541 aagccgacat actcatctag attaaatgtt tccacttgag acacgtcgag ttggtttttt
    18601 tgaagtaatt ccactaaata gtcatacact ttaaccattg tgccacccgt cgctaatcct
    18661 aaacgactgt ctttttgata taacatttgt ttaaataatt cgctcgcaac gtaaaatgat
    18721 gcattcgctt cacgacctaa attaatgatc ttcattatgc ttattcctcc tcaatcattt
    18781 tcacgaaacg tttcgtaata tcacgtggtc tcgtaatggc accaccaaca actgcagcat
    18841 acacacctaa atccatgact gtttttaaca tttcaggcgt gatcacattc ccttcagcga
    18901 taactttttg cgatacattc gctagcacgt cttttaaaaa cgcaaaatca ttggcgtata
    18961 acacttgacc tgtcgtttgc tctgtatagc catgtaacgt cgtaccaata taatcaaagc
    19021 cgagacgttc tgcattttgc gcttcttcta ccgtcgcaat gtctgccata atttcaacat
    19081 ccggcgctgc tttacggata tattgtacta aagtttctaa atcttcagca ggacgttcac
    19141 gtaatgtcgc atccatcgca atcacttcac atccgctttc aataagttca tctacttctt
    19201 tttgtgtcgc agtaataaat acggaagagt tgtcatagtc tcgcttcaca ataccgatga
    19261 ctggcaaatc cacctctttt ttaatcgcta aaatatctgc tttcgtattc gctctaatcc
    19321 caacagcgcc cccttgcttt gcagctaacg ccattttccc cataatgaat gatgaatgga
    19381 gtggctcatc tggtaacgct tggcaagata cgattaatcc ttgtgttaaa ttcatctaat
    19441 gactcccttc taattgttct tctacttcat ttttaatggt tgaaacgtga ggtccataga
    19501 caatttggac gccgtttcct ttcgtaatga ttcctttagg ttcagtacct tgaatcaagc
    19561 tttcatttac tttttgtgta tcttttaacg tgactctcag gcgtgtcgca cagcaatcga
    19621 ctatttcgat attttcatgt ccacctaaac cttgaataat ggttgtcgca cgttcatttg
    19681 tttgtacgct ttgttgcgtt gtctcatctt cacgccccgg tgttttaaag ttaaacattt
    19741 gaattaacat tctaaaaatc acatagtaaa gtgcgaacca gacgagaccg attggaataa
    19801 tccataaata attcgttttc gcttggcctt gtaaaacacc aaacaagata aaatctataa
    19861 aaccaccgct aaacgtctgc ccaaccgtaa tgttaaaaat atctgccatc ataaacgcta
    19921 aaccatctaa taatgcatga acaacgtaaa gtaatggggc aacaaataaa aagctaaact
    19981 ctaacggctc cgtaatacct gttaaaaaag acgttaaagc tgcagataac attaaaccac
    20041 cgaccacttt tttgcgctca ggttttgctg tatgatatat cgcgagtgcc gcacctagca
    20101 gtccaaacat cattgtaata aaacgccctg acatataacg cgaaacgcct tcataataat
    20161 gtgccgttgc agggtcacct aattgtgcaa aaaagatatt ttgcgtccct tgaatcaatt
    20221 tgccattcaa ttcgagtgaa cctccgagcg cggtttgcca aaatggaaga taaaaaatgt
    20281 gatgcaatcc gaaaggccct agcattctca atatgaaacc atataggaac gtaccaatga
    20341 cgcctgtttg cttcacaatt tggcctgctc ccataatcgc atgttgaaat aacggccaaa
    20401 taaagaacat cactaaacct aatacaatag atgcaaaagc tgtcacaatt ggaataaagc
    20461 gcgagccccc aaagaaacct aaaaactgcg gtaatgtgat tttgtagtat tgattatgga
    20521 gcattgccgt tatgataccc acaatgatcc ccccaaacac gcctgtctct acagtttgaa
    20581 tacctaaaac catcccttgc ccagccttag cgagttggtc aggtgccgcc acctgttctg
    20641 taattgttaa aaggccgctc atcgttgcgt tcataattaa aaagcctaac atcgcagcta
    20701 acccagcagt acccttatct gctcgtgcca aaccgactgc aacacctatc gcaaacaata
    20761 ctgacaagtt ttgaaacaca atactgccag ccgtccgcat taatataaac aaatgttgca
    20821 acaatggaat atttaaaaat ggatatgctt cgatagtgtt cggattactc agtgcgcctc
    20881 caataccgag taataatcct gctgccggta aaatcgcaat tggtaacata aaggacttcc
    20941 caaattgctg cgctttatca aataatgtat tcaatcttgt ccccctcttc ttccctgttc
    21001 actctcaata tatcactaag aaaatttccg tcaacaaaat acgttgtttt ggaaattatt
    21061 ttcaaatata ctgagtttaa aaggaggatg acgatgaaaa ttgaaaatcg tattcaacaa
    21121 aatcaacatc atttcacaaa agttgaccag caaatcgctc aattcatttt gtcggtagat
    21181 gatcatacgg acttaggtgc aattaatcag ttagcggatg cgattggtgt gtcaccttct
    21241 agtattacac gctttgcaca taaattaaat tatgatagct tccaatcgtt tcgtttcgcc
    21301 atccaacacg aactgcaaac ggaaccgatt cacaatagtc cttccattca aattttgcat
    21361 caacattatc gcgccatcat ggatcacacg ggtgaatttc tcattgaaga tgatttgatg
    21421 tacctcgtca acacgattga acagagtgat aaaatcattt ttatcggtat tggtagttct
    21481 ggattaagcg cgcaagaatt gtactttcgc acgtcgagaa tgggcttcaa cacgctcgct
    21541 attacggatg cgcatttaat gacagtcatt gggcacatgt gtcatggcaa tactacgatc
    21601 gtcgctttta cgaatagtgg cgcaacgaag gaaattatgg atagtttaag tcatggtcgt
    21661 gaaaacgggg cgactgtgat agccatttct cattttcgga cacctgcact g
//
