LOCUS       NZ_CP065920            30622 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus pseudintermedius strain SP_11306-1A chromosome,
            complete genome.
ACCESSION   NZ_CP065920
VERSION     NZ_CP065920.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2605463)
  AUTHORS   Byukusenge,M., Banovich,F., Li,L., Kuchipudi,S.V., Jayarao,B.M. and
            Naikare,H.K.
  TITLE     Complete genome sequences of Staphylococcus pseudintermedius strains
            isolated from canine superficial pyoderma lesions in Georgia, USA
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2605463)
  AUTHORS   Byukusenge,M., Banovich,F., Li,L., Kuchipudi,S.V., Jayarao,B.M. and
            Naikare,H.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2020) Veterinary and Biomedical Sciences,
            Pennsylvania State University, Wiley Ln, University Park, PA 16802,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 233x
            Sequencing Technology             :: Illumina & Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016126755.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 13:13:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,469
            CDSs (total)                      :: 2,387
            Genes (coding)                    :: 2,345
            CDSs (with protein)               :: 2,345
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 13 of 42
            Pseudo Genes (incomplete)         :: 29 of 42
            Pseudo Genes (internal stop)      :: 14 of 42
            Pseudo Genes (multiple problems)  :: 12 of 42
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:44:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 833682
            Orig. end                         :: 864304
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065920.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..30622
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="CDPS"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="3"
                     /rules="CDPS"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..30622
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="neighbouring"
                     /product="CDPS"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20707
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20707
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10707](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10707
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            234..890
                     /gene="tsaB"
                     /locus_tag="JC281_RS03690"
                     /old_locus_tag="JC281_03690"
     CDS             234..890
                     /EC_number="2.3.1.234"
                     /GO_function="GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tsaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729420.1"
                     /locus_tag="JC281_RS03690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03690"
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="WP_063278594.1"
                     /transl_table=11
                     /translation="MYSLLIDSANQPLSVAIMQEGHVLITHTTTIKRNHSVQLMPLIEW
                     LLQQAQLKPKDLDEIIVTEGPGSYTGLRIGVTTAKTLAYTLNIRLYGVSSLKAIAAQIQ
                     YSDAYIIPVINARRQHVYAGVYQWQQGELVNVMSDQYIPLDRLIEQWTTNDNVIFVGED
                     VAQFETELAPFKRLSAPPRADQMYPHKGAPRDIHTFTPQYLKLSEAEQNWLNQQK"
     gene            869..1339
                     /gene="rimI"
                     /locus_tag="JC281_RS03695"
                     /old_locus_tag="JC281_03695"
     CDS             869..1339
                     /EC_number="2.3.1.266"
                     /GO_function="GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rimI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613398.1"
                     /locus_tag="JC281_RS03695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03695"
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="WP_014613398.1"
                     /transl_table=11
                     /translation="MAESTKIEDQLQIRRMSHEDVPEVFDLEQASFQHSSWTIDAFYYE
                     LEQNNFAHYFVLEYDQRIIGYLGLWVVVDQAQVTTIAIDAAYQGHGLGQMLLKYGMNYV
                     GSIATVMSLEVRVDNVVAQHVYRKLGFQFGGKRKNYYGDGEDALVMWVNLYE"
     gene            1332..2354
                     /gene="tsaD"
                     /locus_tag="JC281_RS03700"
                     /old_locus_tag="JC281_03700"
     CDS             1332..2354
                     /EC_number="2.3.1.234"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tsaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613399.1"
                     /locus_tag="JC281_RS03700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03700"
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="WP_063278593.1"
                     /transl_table=11
                     /translation="MNEQTKILALETSCDETSVSVIENGQTILSNSVLSQIESHQRFGG
                     VVPEVASRHHVENITVMIEEALQQAHTSIEDVDAVAVTQGPGLIGALLVGVNAAKALAF
                     ANDKPLIPVHHIAGHVYANQLQSGLKFPLIALIVSGGHTELVYMENHLQFEVIGETRDD
                     AVGEAYDKVARKIGLPYPGGPAIDRLAAQGEDTYDFPRVWLEPDSYDFSFSGLKSAVIN
                     KLHQLEQKGDPIIPENVATSFQNSVVEVLVGKAMRACEAYGVKQLIVAGGVASNRGLRH
                     ALEVATAEKGIELAIPEPKLCTDNAAMIGAAAHEIYLKGIRGDMALNGQSSMDIEMYRD
                     "
     gene            complement(2590..>2808)
                     /locus_tag="JC281_RS03705"
                     /old_locus_tag="JC281_03705"
                     /pseudo=""
     CDS             complement(2590..>2808)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495236.1"
                     /locus_tag="JC281_RS03705"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03705"
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KARRLLYLIIMNIIRGRNHYQSHIVDYYYKLREQPHGKSHKTAVI
                     ASINRLLKTIHYLIVNNKLYDYQKAPH"
     gene            complement(3337..4920)
                     /locus_tag="JC281_RS03710"
                     /old_locus_tag="JC281_03710"
     CDS             complement(3337..4920)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613401.1"
                     /locus_tag="JC281_RS03710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03710"
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="WP_198456172.1"
                     /transl_table=11
                     /translation="MSSNTFFILLLVVALVGMTLITETVRRIRHQRILTYHLEHFTRFD
                     TTENPHAVYDAYFNSRHTATNTIIDDKTWSDLSMDLLFDKLNATYTSIGENHLYSALRL
                     QTSLVHYEFLEQLRPYPNQHREIVKRLVDLGKSIYPNYDKDILKQQYQWVYAFLLAMPF
                     VGLMISFFNLGIGLLWICFAFFLNIIISFRYNYYVEKDLKQLFIMGRVVRETEILSKMT
                     ITPEFNHSLKPLSSISRLRFLLINVETIPGYFVMVFKYMFLVDIHLYATLVRRFIKHYD
                     TVLECYRYIGELDSLLAVYQYRCHYDTSEPVEADHVTFEGLTHPLIDEAVPNDFDFNQN
                     VLITGSNASGKSTFMKAVALNLIMAQAIRTVTADKFHYTPGMVKTTMANADDVTSGDSY
                     FMAELKSLKRLFLQDAAVQHYYFIDEIFKGTNTTERVAASHAVLDYLNQLSHLKIIAAT
                     HDIELTEVLAHQYANYHFNEHVTDGEIVFDYHIKEGPANTRNALELIRIMQFPNRIYTD
                     AQAYVKQLET"
     gene            complement(5283..7235)
                     /locus_tag="JC281_RS03715"
                     /old_locus_tag="JC281_03715"
     CDS             complement(5283..7235)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729418.1"
                     /locus_tag="JC281_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03715"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_037542574.1"
                     /transl_table=11
                     /translation="MILMQLSQITKSFDGEEIFEGVNFEVKTGERIGIVGRNGAGKSTL
                     MKIIAGVESYDSGHISKIKGLKLGYLTQQMTLNTENTVFEEMAKPFEQVKAIGKRMQEE
                     TDWLAAHAEAYETTEYQTHIAKYEQLSNEFEQLGGYHYDSKIKTVLNGLDFSEADYDRP
                     INDFSGGQKTRLSLAQMLLSEPDLLLLDEPTNHLDMATTEWLEDYLKYFKGAIVIISHD
                     RFFLDKIVTQIYDVSLGEVKHYVGNYAKFIQLRDQYFQKRLAEYERQQSEIKRLETFVE
                     KNITRASTSGMAKSRRKMLEKMTRIEKPMLDARSANIQFDFDRNTGNDVMHIQDLEIGY
                     RTPITAPIRFEINKGDHIGIIGPNGIGKSTLIKTLAKRLPPLSGQIIEGANLKIGYYDQ
                     KQAEFRSNKTILDFVWDQYPHMPEKDVRAVLGRFLFTQDEVLKVINDLSGGEKARLQLA
                     LLMLERNNVLILDEPTNHLDIDSKEMLEQALKNFEGTLIFVSHDRYFINELANRIFDLN
                     KTGGHLYLGDYQYYLEKLEQQNALAAYDEQREDNNTSDDSARSQNTYQDQKALRREKRK
                     IERQIEADEQKITELEARIAAIDVAMTDDTTMNDYEKTQALANERTSIEQSLEQVMTNW
                     EELQLTISQFEDEMD"
     misc_feature    complement(7342..7357)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            7389..8036
                     /locus_tag="JC281_RS03720"
                     /old_locus_tag="JC281_03720"
     CDS             7389..8036
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613403.1"
                     /locus_tag="JC281_RS03720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03720"
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="WP_063285002.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.9e-07, bitscore:
                     28.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKSMNKIPRATLKRLPLYYRFVNTLKAKGEDRVNSKAISEGLNI
                     DSATIRRDFSYFGELGKKGYGYNIDSLLEFFKSELSDSDIIKIGIVGVGHLGTALISYN
                     FSIHDDMTITEAFDIREDIIGTTVGDITIKPMDDIKETIASGELEVVIITTPESAAQAV
                     TDQLVEAGIKGILNFTPKRVHAPQSVQVHQIDLGIELQSLLFFMKNYGTSEA"
     gene            complement(8202..9386)
                     /locus_tag="JC281_RS03725"
                     /old_locus_tag="JC281_03725"
     CDS             complement(8202..9386)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613404.1"
                     /locus_tag="JC281_RS03725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03725"
                     /product="MFS transporter"
                     /protein_id="WP_198456212.1"
                     /transl_table=11
                     /translation="MIQTKHDFNLYILCFLAFFASLIQNIYTPIIPKLHDSFQVSLFWI
                     NFTVGGFIFIVAIMQILLGKNIDSKNSKRTLLVGLGIVIISSFICSITNNFIIFVVSRL
                     LQAISCGIIPLVTLTLLAQLTTNNERASVMANYQIFLSCAPALAPILGSVLGAKWNYFG
                     IFVFLLVVSILLFIVLYLIDIPDAIKAVAQSNVDLSGKSYLTDKVFITLVFLGFLVFFT
                     YFSILVYLPILLSNSYSIAPSMIGILFLPITTSVIIGSIVYKKISKVKDSMTILRNTVI
                     TFAIFTLSFGLMHYLNLIVLSLIIFALGFLVGIVPALLSTLISQRYENIKGKVLGIFNF
                     IRYLGMTFGSITIGLISQQYMLFYFSFIFIVMLTIFLYIKTVHFNQAMTDIYHL"
     gene            complement(9367..9846)
                     /locus_tag="JC281_RS03730"
                     /old_locus_tag="JC281_03730"
     CDS             complement(9367..9846)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613405.1"
                     /locus_tag="JC281_RS03730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03730"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_014613405.1"
                     /transl_table=11
                     /translation="MNKQQKVIITLQQFIIERENANKRRKNIKGDEGLNLSLTQFHIIE
                     LIANNDKVNNKFLADKLNISNPAVTKSIKKLLSKDLVLELQNAQNKREVHYKLTKKGKK
                     LSSIHDELHNQAVKKYEEVLKVFNEKELDVIVEFLSRSISALKEEEVDYDDSNKT"
     cand_cluster    9917..30622
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    9917..30622
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[19916:20622](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(19917..20622)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="2"
     gene            10001..10477
                     /locus_tag="JC281_RS03735"
                     /old_locus_tag="JC281_03735"
     CDS             10001..10477
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="JC281_RS03735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03735"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_250882955.1"
                     /sec_met_domain="CDPS (E-value: 6.4e-38, bitscore: 127.7,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQQFKVDFLTENCKKIYQRKKHVILGISPFTSKYNETYIRKLIQ
                     WANTNFKDFSILLAGEESKNLLECLGYSTTKANRKVRKEVNRQIRFCENELLNCNRTIN
                     DRIFRFSDFKQNTYYVNMYQKIEGLFNTDDSFKKCCLNMSLQALQSKKIISIQQ"
     gene            10492..10707
                     /locus_tag="JC281_RS12550"
     CDS             10492..10707
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="JC281_RS12550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_242442445.1"
                     /sec_met_domain="CDPS (E-value: 1.3e-14, bitscore: 51.6,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEYSAQYVLAELPFFLNANPIINTYETLMAYHAEWELGTNIINN
                     MFDLKMDSHQGYIILTDRGDNYVKTI"
     gene            10691..11890
                     /locus_tag="JC281_RS03740"
                     /old_locus_tag="JC281_03740"
     CDS             10691..11890
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613407.1"
                     /locus_tag="JC281_RS03740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03740"
                     /product="cytochrome P450, cyclodipeptide
                     synthase-associated"
                     /protein_id="WP_070407750.1"
                     /sec_met_domain="p450 (E-value: 5.8e-34, bitscore: 114.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQSKSIFDEAYEINPIPYFNYFREYAPIHYEESVNAYFVSNYE
                     DVKFILKSDGIFTTKTLAERAEPVMKDRVLAQMTGHEHRSKKKEILKGMSGKYLDRLLP
                     IIEKRTNNLIDKYINEKRIDLVNDFGKIFAVQSSMDLLGIDIRDSDKIREWHNGIAKFI
                     TSFNMSSEDVKYSLSCSDKLEKYLMPLIKERKGIKKLDLISVLNDYKDEKSQITDSEIL
                     ALILNILLAATEPVDKTLAYLFYNLLNNPNQYQDILDNPSLLKNAIIETLRFNSPVQLI
                     PRQLSMPYTFRDKKLNVDDVVICMIGAANRDPKAYTAPDEFNIYRKSKNNKPFTSYSQN
                     LSFGFGAHTCIGATYALIQLELVVRTLLKRLKNIKLETNVLHERGIYTRGPKSLIISFD
                     "
     gene            complement(<12433..12547)
                     /locus_tag="JC281_RS03745"
                     /old_locus_tag="JC281_03745"
                     /pseudo=""
     CDS             complement(<12433..12547)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029204.1"
                     /locus_tag="JC281_RS03745"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JC281_03745"
                     /product="ribose transporter RbsU"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNMVALLIGLGPLLDWIFSYNRIKIWR"
     gene            12884..13831
                     /locus_tag="JC281_RS03750"
                     /old_locus_tag="JC281_03750"
     CDS             12884..13831
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613408.1"
                     /locus_tag="JC281_RS03750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03750"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_099997326.1"
                     /transl_table=11
                     /translation="MNIQDIANLAGVSKSTVSRYLNQGSISLKTKRKIQHVIDTYGYEP
                     NQFAQSLRAQKSMMIGIIFPRMYSHAVSQTVKGIKAKCDAFGYQMLLNLTERHVEQELD
                     ALKSFKRSKVDGILFMATTVTDAHMAVIQEIDKPVIIIGQAHASLSSVYHNDYQAGQLM
                     GREIVAQGKQHVIYASIQEDDVAVGEQRFRGLIEVLTANQVTYETLMTSFDYETALQSI
                     KGQLTQQPSVAYVGATDTIALALYQALMHDHMTEPPWIAGFGGDPMTQIVHPMIFTLPY
                     QYEAAGRIAFEQLQLQMEQPDLIQSCQLDVNSKL"
     gene            13887..15371
                     /locus_tag="JC281_RS03755"
                     /old_locus_tag="JC281_03755"
     CDS             13887..15371
                     /EC_number="3.2.1.26"
                     /GO_function="GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613409.1"
                     /locus_tag="JC281_RS03755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03755"
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="WP_198456173.1"
                     /transl_table=11
                     /translation="MEQWSREKRYRKYEEATHEEMELLTAKVNRSPFRQTYHIQPPTGL
                     LNDPNGLIFFNGQYYIAHQWFPLGAVHGLKYWRLLTSNNLVQFEDRGVVLRPDQTFDSH
                     GVYSGSAFSFHQKLYYMYTGSHRDNEWNRHSSQIVAEVQANGSVRKLLPPAIPAPPQGY
                     TQHFRDPKVFEKDGKLYTLLGAQRENETGCAVLYEAERPEGPWQFKGEIQTQLEDFGYM
                     WECPDYFQIHGKDILLFCPQGIESEGDAYQNIYQSGYIMGTLNFDTLEFDHGPFIELDH
                     GFDFYAPQTMTDEAGRRVLIGWMGLPDTEYPTDDDGWAHCLTLPRTLTIEDGKLKQKPH
                     MHLRKLRKNEEVALGYANKFIKQLHPYEGVQYELVVDILENEASAFELQLRASRNESTT
                     IRYDATTRQVSLERFDSGALPYPVEGTMRVTQLHTDLKQLRIFVDTSSIEIFCNEGERV
                     LTSRIFPKATSNKFKVVTDSGQIYLKMTKYDIVEGG"
     gene            15375..16319
                     /locus_tag="JC281_RS03760"
                     /old_locus_tag="JC281_03760"
     CDS             15375..16319
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166402.1"
                     /locus_tag="JC281_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03760"
                     /product="carbohydrate kinase"
                     /protein_id="WP_198456174.1"
                     /transl_table=11
                     /translation="MKRFYAIGEALIDFIPTQRETPLKDVTGFEPQVGGAPCNVAAAVQ
                     KLGGNSHLITQVGEDAFGDKIIETLQAVEVDISHILTTKEANTALAFVSLSNDGERDFS
                     FYRKPSADMLYEAENIDTIELQQGDLVHFCSVALVDSPMKRAHVTLLDKSEQVGATVVF
                     DPNVRLPLWDDHDVYYETLQAFLPRAHVVKVSDEELSFVTRYEDEAEALKSLFVGNVQA
                     VIYTKGSRGASLIFEDGSTIEVPTPPAQVVDSTGAGDAFIGAISAKLCQSEQQPIETLR
                     QHGHDILKFAHQVSGRVVSQYGAISSLPTLEEL"
     gene            16513..17832
                     /locus_tag="JC281_RS03765"
                     /old_locus_tag="JC281_03765"
     CDS             16513..17832
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1206: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729285.1"
                     /locus_tag="JC281_RS03765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03765"
                     /product="ISL3 family transposase"
                     /protein_id="WP_100004563.1"
                     /transl_table=11
                     /translation="MCNDISEILGIKVKNLKITQNLGLHVHKNVQALFYEGQLTYHPSA
                     CECCGIKNDNHLIIKHGFRKTNVYMGLIFERPAYLKLKKQRFYCKACQRTFTAETPYIQ
                     PRCTISNEVKRMMTWKLSKVTSEKDIAESLCVSPSTVHRHLKVVSNSVKTHAHYVLPEH
                     LAFDEFKSTKDVEGAMSFIYCDSVTHDIIDILPDRRKHQLEAYFLKFSRKQREKVKTVS
                     IDMFPPYIALIQDLFPHAEIIIDRFHIVQAINREINRCRVQVMNGFRTKERPQYNKLKR
                     YWKLLLKAPIDLDRMIYQPYRLFKSWQSQYSLVQYLLNLDETLKETYETGHRLLSALKA
                     NDIQQLRFILQDAKTKDISKGLKRVIHTFIKYMPYISSTMRHRHLTNGPIEGINNKIKL
                     IKRVSYGYRNFWNFRNRILMISKVFVSEYKKHIKQQNNVA"
     gene            complement(17871..18587)
                     /locus_tag="JC281_RS03770"
                     /old_locus_tag="JC281_03770"
     CDS             complement(17871..18587)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688500.1"
                     /locus_tag="JC281_RS03770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03770"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_100006618.1"
                     /transl_table=11
                     /translation="MKILICEDDPKQRERMVSIIENYIMIEEKPMKIELATNDPYAILE
                     TSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAA
                     MDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDEVMFFE
                     SSPKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSYVLNRRNITSVDTKERIAYF
                     KNEEFCYVSVRNLKKI"
     gene            complement(18601..19656)
                     /locus_tag="JC281_RS03775"
                     /old_locus_tag="JC281_03775"
     CDS             complement(18601..19656)
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729415.1"
                     /locus_tag="JC281_RS03775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03775"
                     /product="sensor histidine kinase"
                     /protein_id="WP_233535950.1"
                     /transl_table=11
                     /translation="MLLTILVLMINDFIATWIFAYLNTYHINFYVTSLIYMVVFALGCC
                     LFSYIIITLFNKLKTSWLYINKIYLIALVVFLACGFVIFFSFLPRSVGDIYEFQYFGII
                     CFISFSVFAILIIATTLTIEREINYKRKKQELDDYYKYTVQIEKINNKMRKFRHDYTNI
                     LLTMSEYLREDDLEGLKQYYHEHISPLKSEFESNTMRLNGIENLKVREIKGLITTKILQ
                     AQENNIEITVEVADEITQIDMDAIQLSRVLGIIMDNAIEASNTIEDPIIQIAFIKTDAS
                     VMIIIMNKAPKDMPKLHTLFQDGFSTKGNNRGIGLTTLKEIIDQTDNVFLDTTIENHYF
                     IQKLEIMNDYE"
     gene            complement(19917..20054)
                     /locus_tag="JC281_RS03780"
                     /old_locus_tag="JC281_03780"
     CDS             complement(19917..20054)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613413.1"
                     /locus_tag="JC281_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03780"
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="WP_063278585.1"
                     /sec_met_domain="TIGR04223 (E-value: 5.2e-07, bitscore:
                     26.8, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILEVLFNLITNLFQSIGTFARIPTSTGFFDEPEIPAELLEEDK
                     "
     gene            complement(20056..20622)
                     /locus_tag="JC281_RS03785"
                     /old_locus_tag="JC281_03785"
     CDS             complement(20056..20622)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613414.1"
                     /locus_tag="JC281_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03785"
                     /product="accessory gene regulator AgrB"
                     /protein_id="WP_198456175.1"
                     /sec_met_domain="AgrB (E-value: 2.6e-31, bitscore: 105.5,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLIDNGIEKMALKLQQRQNLSHIEFLKVRLGMQVVVINSFKAVV
                     TYGLALLLNIFLYTLIVHLTFLALRTYSHGAHAKTSMLCHVQNIASFVVLPWLIVQYDI
                     SFQFLLSLSILAAMIVIKYAPAATKKRPIAPRRVKGLKIKSIIVFIILMTLAFIVPTPY
                     NRFVVYGVLLQSFTLLPIFSTKEEV"
     gene            complement(21378..22181)
                     /locus_tag="JC281_RS03795"
                     /old_locus_tag="JC281_03795"
     CDS             complement(21378..22181)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166407.1"
                     /locus_tag="JC281_RS03795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03795"
                     /product="carbon-nitrogen family hydrolase"
                     /protein_id="WP_014613416.1"
                     /transl_table=11
                     /translation="MQIQLFQINVAIANSRQNEQKIATLFEQHLDDQTDVVVLPEMWNN
                     GYALPQLDKLADEDLAQSYAFIQKLAQNYQVDIVAGSVSNRKEGAVYNTAFAVNRRGEK
                     IYEYDKIHLVPMLDEPDFLTCGKSVPYPYSLSDGTSVSQIICYDLRFPELSRYPAAQGA
                     KVMFYVAQWPEVRLTHWRQLLQARAVENDMYVVAVNGSGHDGKTTYAGHSMVVDPNGEI
                     IAEADENETVMTVTLDLQKVDTQRRAIPVFENMRPSVYRYAQKEI"
     gene            22346..23707
                     /locus_tag="JC281_RS03800"
                     /old_locus_tag="JC281_03800"
     CDS             22346..23707
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613417.1"
                     /locus_tag="JC281_RS03800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03800"
                     /product="SdrH family protein"
                     /protein_id="WP_198456176.1"
                     /transl_table=11
                     /translation="MVEYKKEHSVKRLLKLGIGSTSILCVVSPLLLTHDVVQAADINNR
                     MPALNTLKTTSSYDQRAHMDELRSAITSDSDTTQTPSFNEITVSSTNETDAASTENVNP
                     SDEVSAKDESESTTPSTEQDTSIEETGTEEVPSHEDNHHNTPSQEQQPSPPDQPGTNKD
                     EESGEKPNKENHRKPNQPNKDQPSKDENKKPDKGNKPAPPSKAPNRPDQKEEGSNNTPP
                     PATDNGGNSNDGTTTGPNGGGGSEASPPPNEQPSNGNASDTHQNGSVSSTNHSNQYGTS
                     AYDEYAGLLNNNYKYNPLFKEEVARLSQFGSQDQHDIASLSRKEQFSQNAFLDDLQQST
                     DYFRYQYFNPLSTEQYYHRLDKQVLALVTGEFGSMPDFKKSGDKSLVNKHQQDKVKKIE
                     QQGENINTHHMKNTKEDTGKSLSYKPMIYIGIVMVGFVGLISMILWKRLHHFWK"
     gene            complement(23819..24586)
                     /locus_tag="JC281_RS03805"
                     /old_locus_tag="JC281_03805"
     CDS             complement(23819..24586)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166409.1"
                     /locus_tag="JC281_RS03805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03805"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_063278583.1"
                     /sec_met_domain="Abi (E-value: 4.3e-16, bitscore: 56.3,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRFWVSLLTVVLYILAQISPYIARAVGWIQTGNQAQLLRQSIAV
                     QFTAFIIVAILIIILQLFVKNKLNFELGPKEKKRYVLPYILVGLVIVFIAQMVVNLISV
                     QLFGANPASENTLRIMKIARQMPIFIVLIAIVGPLLEEFVFRKVLFGELYHAIKANQWV
                     KFTIATTISSAVFAVVHMDFSHFLAYFVMGIIFSAFYIYTKRLSVSIGIHMAQNGLVAL
                     IQLMMPEKMIEEAVKQTQFILLLTSHWMSFFLS"
     gene            24756..25043
                     /gene="groES"
                     /locus_tag="JC281_RS03810"
                     /old_locus_tag="JC281_03810"
     CDS             24756..25043
                     /codon_start=1
                     /gene="groES"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275309.1"
                     /locus_tag="JC281_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03810"
                     /product="co-chaperone GroES"
                     /protein_id="WP_015729412.1"
                     /transl_table=11
                     /translation="MLRPLGNRVVIEKKEHEQTTKSGIVLTDSAKEKSNEGVIVAVGPG
                     RILDNGERLKPELNEGDRVVFQQYAGTEVKRDDKEYLVLTEDEVLAVIED"
     gene            25092..26711
                     /gene="groL"
                     /locus_tag="JC281_RS03815"
                     /old_locus_tag="JC281_03815"
     CDS             25092..26711
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500736.1"
                     /locus_tag="JC281_RS03815"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03815"
                     /product="chaperonin GroEL"
                     /protein_id="WP_014613420.1"
                     /transl_table=11
                     /translation="MAKELKFSEDARQAMLRGVDKLANAVKVTIGPKGRNVVLDKEFTA
                     PLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLK
                     NVTSGANPVGIRQGIDKAVAVAIESLHNISQKVENKEEIAQVGAISAADEEVGRYISEA
                     MEKVGNDGVISIEESNGFNTELEVVEGMQFDRGYQSPYMVTDSDKMIAELERPYILITD
                     KKISSFQDILPLLEQIVQSNRPILIVADEVEGDALTNLVLNRMRGTFTAVAVKAPGFGD
                     RRKAMLEDLAIVTGAQVITDDLGLELKEATLDMLGTANKVEVTKDNTTVVDGDGDTANI
                     DARVGQLKAQIEETDSDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALN
                     STRAAVEEGIVAGGGTALMNIFKDVQAIEAEGDEATGVNIVLKALQAPVRQIAENAGLE
                     GSVIVERMKNAEPGIGYNAATDEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAV
                     VANIPEDKGNDMPQMGGMPGMM"
     gene            26992..27135
                     /locus_tag="JC281_RS12420"
     CDS             26992..27135
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013828.4"
                     /locus_tag="JC281_RS12420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_226957587.1"
                     /transl_table=11
                     /translation="MKYLTVFNFTFQSSINKQEIFTLKSMHFQEKSINIYFIGNSGGHN
                     NF"
     gene            <27378..28007
                     /locus_tag="JC281_RS12425"
                     /pseudo=""
     CDS             <27378..28007
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708297.1"
                     /locus_tag="JC281_RS12425"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="SAR2788 family putative toxin"
                     /pseudo=""
                     /transl_table=11
                     /translation="NKNIKNTKISEDKNGEVSRLSTSINNRELDLDTVLTNDFKTGDIN
                     LSGEISNIEESKQVDYTIDLTYADEKDIAGFLIDNLTGEEHEFDTRLAEASAAPIVVVA
                     VMAARYGIQWAIKKYGKKAVSNAIKSNTHKVAKGINSSLLTSKGVDIGKFTQKVRGKNP
                     VYRDPKTGWSISKNKGQPHGGSYWKLLDKGGTRKATLTKDGKILRK"
     gene            28022..28627
                     /locus_tag="JC281_RS03825"
                     /old_locus_tag="JC281_03825"
     CDS             28022..28627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368755.1"
                     /locus_tag="JC281_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03825"
                     /product="DUF3885 domain-containing protein"
                     /protein_id="WP_015729409.1"
                     /transl_table=11
                     /translation="MSNIISCMEVSGLKFSEGENAVHLDLSEGEYPFLDDGKSFNKDYF
                     ARIHNNAIQILQDLFQQSNTIDIVLLYYLYGDSFKKTRFKEKFSYFNNNEIPDFKEYIN
                     DEGIQCYIFSYKNKNLKDLNYKKLVRAISNQDFKGLFPTINQKDNYLDIYLMDSKRGIL
                     FHLYDDRGLWLYFLNKQSYKIYSQKYSNLLFDVSHEMD"
     gene            28614..29315
                     /locus_tag="JC281_RS03830"
                     /old_locus_tag="JC281_03830"
     CDS             28614..29315
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729408.1"
                     /locus_tag="JC281_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_03830"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_103863236.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.4e-14, bitscore:
                     49.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKWIKVYLKLIILILLSVFIYLNYNCKYEKSKIAVLDTGVEKKAI
                     KSKVISRNFTLDNNSNSVHANKVSKIIEYEADIVIYDAKVLNRHGNGRLEDTISALDWA
                     IKNNVDIINMSYGFTKNYPELHRKIKEAHEKGIIIVAANGNDIFGGKEFPASYKETISV
                     GVLNKEGSKSVFNSNDDADVFISVDNKLPNSGENTSMATAYVSNKLTKLCNRNLRNMDK
                     DEILKLINELN"
     misc_feature    29529..29540
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.7"
                     /tool="antismash"
     misc_feature    complement(30019..30028)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.15"
                     /tool="antismash"
     misc_feature    complement(30514..30530)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.13"
                     /tool="antismash"
ORIGIN
        1 gaaatttcat cacatggatt gttatcgatt agaagattct gatgaagact taggatttga
       61 tgagtttttt gaggatgaag cggtgactgt agtggaatgg agtcaattta ttcaagacta
      121 tttgccacca cattatttga aaatcaacat tcaaacgata aacgaaacag aacgagagct
      181 gagttttgaa gcacatggct cacattttga agagataaag gaggccatcg aacatgtaca
      241 gtttactgat tgatagtgcc aatcagccat tatcagtagc gattatgcaa gagggtcacg
      301 tattgataac gcatacgaca acgataaaac gtaatcactc ggtgcagctc atgccactca
      361 ttgaatggtt attacaacaa gcacaattga agccgaaaga tttagatgaa attattgtca
      421 cagaaggtcc tggttcgtat acaggattac gtatcggggt gacgacagcg aaaacacttg
      481 cttacacatt gaatattcga ttgtatggcg tgtcatcgtt aaaagcgatt gcagcacaaa
      541 ttcaatattc tgatgcgtat attattccag tcatcaatgc gagacgacaa cacgtttatg
      601 ccggtgttta tcaatggcaa caaggtgaac ttgttaatgt gatgtcggat caatatatac
      661 cactcgatag gttaattgag caatggacaa caaacgacaa cgttatcttt gtaggtgaag
      721 atgtggcaca atttgaaacg gaattagcac cctttaaacg attaagtgcg ccccctcgag
      781 cggatcaaat gtacccacat aaaggagcgc cacgcgatat tcataccttt acaccgcaat
      841 atttaaaact atcggaggcg gaacaaaatt ggctgaatca acaaaaatag aagatcagct
      901 tcaaattaga cgtatgtccc atgaagatgt gcctgaagtg tttgacctag agcaggcgag
      961 ttttcaacat agttcatgga cgattgatgc cttttattat gaactggaac aaaataactt
     1021 tgcacattat ttcgtgctcg aatatgacca acgcattatc ggttacttag gtttatgggt
     1081 agtggtcgat caagcacaag tgacaactat tgcgatagat gcagcctatc aaggtcatgg
     1141 actaggacaa atgctattaa aatatgggat gaactatgtg gggtctatag cgacagtgat
     1201 gagtttagaa gtacgtgtcg ataatgtcgt tgcacaacat gtgtatcgaa agctcggttt
     1261 ccaatttgga ggcaaacgaa aaaattatta tggtgatgga gaggatgcat tagtcatgtg
     1321 ggtgaattta tatgaatgaa caaacaaaga ttcttgcact tgaaacgagt tgtgacgaaa
     1381 caagtgtgag tgtcattgaa aatggtcaaa cgattttaag taacagcgta ttaagccaaa
     1441 ttgagagtca tcaacgtttt ggaggagtcg ttccagaagt ggcgagtcgt catcacgttg
     1501 aaaacattac ggtcatgatt gaagaagcgt tacaacaggc ccatacatca attgaagatg
     1561 tggatgctgt cgcggttaca caaggacctg gactgattgg ggcgttactc gttggtgtga
     1621 atgctgcgaa ggcactggct tttgcgaatg ataagccgct cattccagtc catcatattg
     1681 ccggtcatgt ttatgccaat caacttcaaa gtggcttgaa atttccattg attgccttaa
     1741 ttgtttcagg tggtcataca gagcttgtct acatggaaaa tcatttgcaa tttgaagtga
     1801 taggggaaac acgtgacgat gcagttggtg aagcgtatga taaagttgca cgtaaaattg
     1861 gcttaccata tccaggtggc cctgccattg accgacttgc cgctcaaggg gaagacacgt
     1921 acgactttcc acgagtgtgg ttagaaccgg atagctatga ctttagtttt agtggtttaa
     1981 agagtgcagt cattaataaa ttacatcaat tagaacaaaa aggtgatccg attattccag
     2041 aaaatgtcgc aacaagcttc caaaatagtg ttgttgaagt gctcgtagga aaagcaatgc
     2101 gtgcatgtga agcgtatggt gtcaaacaac tcatcgttgc tggtggtgtt gcaagtaatc
     2161 gaggtttacg tcatgcgtta gaagtcgcaa ctgctgagaa agggatagag cttgcaattc
     2221 cagagcccaa attatgtact gataatgcgg cgatgattgg tgcagcagcg catgaaattt
     2281 atttaaaagg aattcgtgga gatatggcgt tgaacggtca aagtagtatg gatatcgaga
     2341 tgtaccgaga ttaagttgtt aagtaggtct tgaatatttc aattatgcag agattcatgg
     2401 agattgctga accattctgc gctttctaac aaaatttaat caaaagggat tgggatattt
     2461 ggttttcccg gtcccttttc ctacgatttg tcaagggttc aataattaaa attgacatta
     2521 ctgaactaga ccgtccaatt tttacttttt tgaataaggt gttatgatgt atatgattat
     2581 atggttgcgt tagtgtggtg ctttctgata atcatataat ttattattga ctatcaagta
     2641 gtgaatggtc tttaataagc gattgatact cgctattacg gcagtcttgt ggcttttccc
     2701 atgaggctgc tctcttaatt tataataata atccacaata tggctttgat aatgatttct
     2761 tcccctaata atgttcataa tgattaagta caataaacgt cttgcttttg atggaattat
     2821 attcattatt gatgaaaaca tcgacgaaaa atgagcataa attagataaa aagttgatgc
     2881 tattgttttc tagatttcat aaacttgccc ttagtttcgc tgtatttcat ataatattac
     2941 ccagaaggct gagatgcctg atggaatgca tactgctgac agttgccgct tctctttaat
     3001 agtggttact gtttatcgca gcagctatct gatttctcaa tgtttacact tttgagaagt
     3061 cgagtcagtc atgcgggggc agtacggcga aatctttgtg acacatgata tttctgtaac
     3121 gctcccccca atccattaac gcgtcaacaa gtgtaacagt ttaatcaagt cgaattgagt
     3181 tgaagggcta gcccctagga aacgcgaagc catgagggca atcaaaaaca taattcgtgg
     3241 gagagggcaa ttttaacgag aatattgcat caataacatc aaaaatttta atgccctatc
     3301 tccttttgcg ttatattgat catttttagt atacttttaa gtttcaagtt gcttcacata
     3361 tgcttgagca tccgtgtaaa tacgatttgg aaactgcatg atgcgaatta attccagcgc
     3421 atttctcgta tttgccgggc cttctttaat gtgataatca aacacaattt ctccgtcggt
     3481 cacatgctca ttaaagtgat aattagcata ttgatgagct aaaacttctg ttaattcaat
     3541 atcatgtgtc gctgcgataa tttttaaatg agacagttgg tttaaataat caaggacggc
     3601 gtgtgaagcg gcgacacgtt cagtagtatt tgtccctttg aaaatttcat caataaaata
     3661 ataatgttga acggctgcat cttgaagaaa caatcgtttg agtgatttca attctgccat
     3721 aaagtaactg tcgccacttg tgacatcatc ggcatttgcc attgtcgtct ttaccatacc
     3781 aggagtgtag tgaaacttgt cagcggtcac tgtacgtatc gcttgagcca tgatgagatt
     3841 caatgcgaca gctttcataa atgttgactt accagaagca ttagaccctg ttatcaaaac
     3901 attttgattg aaatcgaagt cattcggtac cgcttcatca atcagtggat gggtcaaacc
     3961 ttcaaatgtg acatggtctg cttcaacagg ctcagacgta tcgtaatgac aacgatattg
     4021 atacactgct aataaactat ccaattctcc gatatagcgg taacattcta aaacggtatc
     4081 ataatgtttg ataaaacggc gaacgagtgt ggcgtataaa tgaatatcga ctaaaaacat
     4141 atacttaaaa accattacga aatatcctgg aatcgtttcg acgttaatta ataaaaaacg
     4201 taaccgcgaa atcgaactta atggttttaa tgaatgattg aactcaggtg ttattgtcat
     4261 ttttgaaagt atttcagttt ctcttacgac ccgtcccata atgaaaagtt gctttaaatc
     4321 tttttctaca tagtaattgt aacgaaaact aataataata ttgagaaaga aagcaaaaca
     4381 aatccataaa agaccaatac ctaaattgaa aaaactaatc ataaggccta caaacggcat
     4441 agcaagtaaa aatgcataaa cccactgata ttgttgtttt aatatgtctt tgtcataatt
     4501 gggataaatc gactttccga ggtcaacgag tcttttcacg atttctcgat gctgattcgg
     4561 gtatggacgc agctgctcta aaaattcata atgaacgagt gacgtttgta atcgtaatgc
     4621 actatataaa tgattttcac ctatggacgt gtatgtcgca ttgagtttgt caaataggag
     4681 atccattgat aaatctgacc atgttttgtc gtcgattatc gtatttgtag cagtatgccg
     4741 agaattgaaa tatgcatcat aaacagcgtg aggattttcg gttgtatcaa accgtgtgaa
     4801 atgttccaaa tggtaagtca atatacgttg atggcggata cgacgcacag tttctgttat
     4861 caatgtcata ccaacgagtg ccaccacaag caataaaatg aaaaaagtat tcgaactcat
     4921 atgtataaat cctttcaata tttttaagat catataaatt tttacacaat atgatgagga
     4981 aatcaataaa ttgtgaaagc gtttgaatca ttgggacatg atttcaaatt catgtagtag
     5041 gaaatctgtc aagagggaac gtgcgtactt atgcacattt tgtgaataac ttgtgtgtaa
     5101 gttcgattca ttttcgtgga taaagtgggg ataagtgtgc ataaagtaag aagaaaacct
     5161 ctcctaaatt gtggataact agaataactt tgtggatagt tgatattatc cgattcttaa
     5221 tgtggatgaa ttgtctgtat ttcgagtata aaaaatgagc ggagtagaaa attccaccac
     5281 gctcaatcca tctcatcttc aaattgactt attgtgagtt gtaattcttc ccaatttgtc
     5341 atcacttgtt ctaaagattg ttcgatactt gttcgttcgt tagctaaagc ttgtgttttt
     5401 tcataatcat tcattgttgt atcatcggtc attgcaacat caattgctgc gatacgtgct
     5461 tctaattccg tgattttttg ttcatccgct tcgatttggc gttcgatttt acgtttttca
     5521 cgacgtaacg ctttttggtc ttgatacgta ttttgtgaac gggccgagtc gtcactggta
     5581 ttgttgtctt cacgttgttc atcgtatgca gcaagggcgt tttgttgctc tagcttttct
     5641 aagtaatatt ggtaatcacc taaatacaga tggccgcctg tcttatttaa atcaaaaata
     5701 cgattggcaa gttcattaat aaaataacga tcgtgtgata cgaaaattaa agtcccttca
     5761 aagtttttta atgcttgttc taacatttcc tttgagtcga tgtcaagatg gtttgtcggt
     5821 tcgtccaaaa tgagtacatt attacgctct aacattaata atgccagttg gagtcttgct
     5881 ttttcgccac cagaaaggtc attaatcact ttgagcactt catcttgtgt aaataaaaag
     5941 cgtcctaaca ccgcacgaac atctttttca ggcatatgag ggtattggtc ccagacaaaa
     6001 tctaaaatgg ttttattaga acggaactct gcttgtttct ggtcgtaata accaattttt
     6061 aaattagcac cttcaataat ttgaccggag agagggggaa gtcgtttcgc taaagtttta
     6121 attaatgtcg atttcccaat accattcggt ccgataatgc caatgtgatc gcctttatta
     6181 atttcaaaac gaatcggtgc tgtaatcggt gtacgataac ctatctctaa atcttggata
     6241 tgcataacgt cattgcctgt attgcgatcg aaatcgaatt gaatgttcgc acttctcgca
     6301 tcgagcatgg gcttttcgat acgcgtcatt ttttctaaca ttttacgacg acttttcgcc
     6361 ataccgcttg tagatgcacg ggtaatattt ttttcgacga acgtttctag tcttttgatt
     6421 tcgctttgtt gacgttcata ttccgcgagt cgcttttgaa agtattgatc acgtaactga
     6481 ataaattttg cataattgcc gacataatgt ttcacttcgc ctagagagac gtcatagatt
     6541 tgcgtcacaa ttttatcgag gaagaagcgg tcatgtgaaa taatgacgat agcaccttta
     6601 aaatatttca aataatcttc taaccattct gttgttgcca tgtctaaatg gtttgtcggt
     6661 tcatcgagta atagcaagtc tggctcactc aataacattt gcgcgagtga gagccgtgtt
     6721 ttttgacctc cactaaaatc attaataggt cggtcgtaat cagcctcact aaaatcaagg
     6781 ccatttaaca cagttttgat tttactgtca taatgatagc ctccgagttg ttcaaattca
     6841 ttagataatt gttcatattt tgcgatatgc gtttgatatt ccgtcgtttc ataagcttcc
     6901 gcatgtgcag cgagccagtc ggtttcttct tgcatacgtt tgccaatcgc tttcacttgt
     6961 tcaaacggtt ttgccatttc ttcaaaaact gtattttcag tatttaaagt catttgttgt
     7021 gttaagtagc cgagttttag acctttgatt tttgagatgt ggcctgagtc atatgattct
     7081 acacctgcga taattttcat caatgtggat tttcccgcac cgtttcgacc tacgatacca
     7141 atgcgctcac ctgttttcac ttcaaaatta acgccttcaa aaatttcttc gccatcaaac
     7201 gatttcgtaa tctgacttaa ctgcattaaa atcatagggc atactccttt cattcttatt
     7261 tattgtacaa caaaccctat atgtatcaaa tactaaatgt ttccttatca tataaattaa
     7321 gttataatta aacacacaca ctgtgaaagc tatcacatat attagaaatc atatcggagg
     7381 acttcaaaat gggaaaatca atgaacaaaa ttcctagagc gactttaaaa cgtctccctt
     7441 tgtattatag atttgtgaat actttaaaag cgaaaggcga agatcgtgtt aattcaaaag
     7501 ccattagtga aggcttaaat atagattcag ccacaatacg tcgagatttt tcttattttg
     7561 gtgaattagg taaaaaaggt tacggttata atattgatag tttattagaa ttttttaaat
     7621 cagaattaag tgattcagat attatcaaaa ttggtattgt cggtgtcggt cacttaggta
     7681 cggcgttaat ttcttacaac ttttcaatac atgatgatat gaccattaca gaagcttttg
     7741 acattagaga agacattatc ggtactacag tcggggatat tacgattaag ccgatggacg
     7801 acattaaaga aactattgct tcaggagaat tagaagttgt tattattacg acacctgaat
     7861 cagcagcaca ggcagtgact gatcaattag tcgaagcagg tatcaaaggt atcttgaatt
     7921 ttacgcctaa acgtgttcac gcgccacaat cagtacaagt acatcaaatt gacttaggga
     7981 ttgaactcca atcgttactc ttctttatga aaaattatgg tacatctgaa gcgtaaaata
     8041 aatcaagtat aaatatttta gtgatttgta tgaatcaaag tgtgagactt catcatttgt
     8101 ttttacaagc aaatgagcgg ttatagcaaa ggctagggga gagatttcct agcctttttt
     8161 gaatttcatg aggaagtcaa ataaaacaac taacgaaaag gttataaatg atagatgtca
     8221 gtcattgctt gattaaagtg tacggtctta atgtagagaa aaattgttaa catcactatg
     8281 aagatgaatg aaaaatagaa aagcatatat tgttgtgata tcagtccaat agttatagaa
     8341 ccgaaagtca ttcctaaata tcggataaag ttaaatatac ctaatacttt gccttttata
     8401 ttttcatacc gttgagatat taaagttgat agtaaggccg gaacaatgcc gactaagaag
     8461 ccaagtgcaa atataatgag cgacaaaaca attaaattta aataatgcat taatccaaag
     8521 gacagtgtaa aaatagcaaa agtaatcaca gtatttctta atatagtcat gctatctttc
     8581 acttttgaaa tctttttata aactatactt ccaattataa cgctagtggt gataggtaaa
     8641 aataaaatac ctatcatact tggtgcaata ctgtatgagt tgcttaagag tataggcaaa
     8701 tatactaata tagaaaagta ggtgaaaaaa actaaaaaac ctaaaaatac taaagtgata
     8761 aaaactttat cggttaaata gcttttccca cttaaatcca catttgattg agcaactgcc
     8821 tttatagcat ctggtatatc aattaagtaa agaactataa ataaaagaat agagactaca
     8881 agtaaaaaaa cgaaaatccc aaaataattc catttagcgc ctagtacact tcctaatatt
     8941 ggcgctaagg ccggggcaca tgacaaaaat atttggtaat ttgccattac ggatgctctc
     9001 tcattatttg tagttaactg agctaacaaa gttaaagtca caagagggat aataccgcaa
     9061 ctaatagctt gcagtaatct agataccaca aatataataa aattgttagt gatagaacag
     9121 ataaaacttg aaataataac aattcccagt cctactaaaa gtgttctttt tgagttttta
     9181 gagtctatat tttttcctaa taagatttgc ataatcgcaa ctatgaaaat gaagccacca
     9241 actgtgaaat tgatccaaaa taatgatact tgaaaactat catgaagttt tggaatgata
     9301 ggtgtgtaaa tattttgaat taaagaagca aaaaaagcta aaaaacataa aatataaaga
     9361 ttaaagtcat gttttgtttg aatcatcata atcaacttct tcctctttta aagcgctaat
     9421 actacgtgac aaaaattcaa caatgacgtc taactctttt tcattaaaga cttttaaaac
     9481 ctcttcatac tttttaactg cttgattgtg taattcgtca tgaatagaag aaagtttttt
     9541 tcctttttta gttaatttat aatgaacctc ccttttgttt tgtgcatttt gtaattcgag
     9601 aactaaatct ttggataaca gctttttaat agattttgtt actgctggat tagagatatt
     9661 taatttatct gcaagaaatt tattattaac tttatcgtta tttgctatta attctatgat
     9721 atgaaactgc gttagagata gattaagccc ttcatctcct tttatgtttt tccttctttt
     9781 attagcattt tctctctcta taatgaattg ttgtaatgtt attatgactt tttgttgttt
     9841 attcataatc atcgtctcct aattgttaac tggttaataa tattattata attaatcttt
     9901 ctgttgtcaa gtagtattgc taaaaatata tgaatctgat atcttattat taaccggaaa
     9961 attgtttatg ggttaactaa agcggaggga ggcgcttata atgttgcaac aattcaaagt
    10021 agatttttta acagaaaact gcaaaaaaat ttatcaaaga aaaaagcatg ttatattagg
    10081 tatcagtcct tttacaagta agtacaatga aacctatatc agaaaactaa ttcaatgggc
    10141 taacacaaat tttaaagact tttctattct gttagctggg gaggaatcta aaaatctatt
    10201 agaatgtctt ggatattcta ctactaaagc taatagaaag gttcgtaaag aagtgaatag
    10261 acaaatcaga ttttgtgaaa atgaattatt aaactgtaat agaaccataa atgacagaat
    10321 attcagattt tcggatttta aacaaaatac ttactatgta aatatgtacc agaaaataga
    10381 gggattgttt aatacagatg attcatttaa aaaatgttgc ttaaatatgt cgttgcaagc
    10441 cctacaaagt aaaaaaataa tctcaattca acaatagaat ttacaaatga tatgttagaa
    10501 tattcggctc aatatgtgtt agccgagttg ccattctttt taaatgctaa tccgattatt
    10561 aatacttatg aaacgctgat ggcttaccat gcggaatggg aattaggtac aaatattata
    10621 aataatatgt tcgatttgaa aatggatagt catcaaggtt atattatatt aactgataga
    10681 ggggataatt atgttaaaac aatctaaaag tatttttgat gaagcttatg aaatcaatcc
    10741 tataccatat tttaattatt tcagagagta cgctcctatt cattatgaag aatctgtaaa
    10801 tgcatatttt gtatctaatt atgaggatgt aaaatttatc cttaagagcg atggaatttt
    10861 tacaactaaa actttagctg aaagagctga accagttatg aaggatagag tcttagcaca
    10921 aatgactgga catgaacata gatctaaaaa gaaggaaatt ttgaaaggta tgtcaggaaa
    10981 atatcttgat agattacttc caatcataga aaaaagaaca aataatttaa tcgataagta
    11041 tattaatgaa aagaggatag atttagttaa tgattttggg aaaatatttg ctgtacaaag
    11101 ttctatggat ttactaggaa ttgatattag agattctgac aaaattagag aatggcataa
    11161 tggcatagca aaattcatca catcatttaa catgagtagc gaagatgtta agtattcact
    11221 gagttgtagc gataagttgg aaaaatattt aatgccatta attaaagaaa gaaaaggcat
    11281 aaaaaaactc gacttaattt ctgttttaaa tgattataaa gatgaaaaaa gtcaaattac
    11341 tgattcagaa attttagctt taattttaaa tattttatta gctgctacag aacctgtcga
    11401 taaaacatta gcatacttat tttataattt attgaataat cctaatcaat atcaagacat
    11461 attagataac cctagtttac taaaaaatgc aataatagaa acacttcgtt tcaattcacc
    11521 agtacagtta atacctagac aattatcgat gccttatact tttcgtgata aaaagttaaa
    11581 tgttgatgat gtggtaatat gcatgattgg tgcggctaat agagacccaa aagcttatac
    11641 tgctccagat gaatttaata tatatagaaa atcaaaaaat aataaacctt tcacttcata
    11701 ctcacaaaat ttatcatttg gctttggagc acatacttgt ataggagcaa cgtacgccct
    11761 tattcaattg gaattggtag ttagaacatt attgaagaga ttgaaaaata ttaaattaga
    11821 aactaatgta ttacatgaaa gaggcatata tacgagagga ccaaagtcat tgataattag
    11881 ttttgattaa tttgttaaaa tatcgattgt caaggtgcta tcaataacta tttactacat
    11941 taaagctttt cgaaaagata aatacagtaa aaataattaa gtttatataa gtatttcctc
    12001 attgatgcat tcaaggacaa tataaaaaat tgtaaattta gaagttgaac atgtttgtat
    12061 tgctcaatca tatacaataa tgaattagaa cctcaatgaa cattgaaagt ttggttagaa
    12121 atagtacttt taaattaaat aagatatttt cttaaggtaa aacaataaaa ataaaaaagt
    12181 ccttccaatt attattcata aacaatgatt tggaaggaca tgcttatgcc tacattagaa
    12241 tgctatacat actgtcagtg attacttaaa aatacagtta cagttgcggt atcaaaaatt
    12301 aattttcaac taataatagt caataccatt tctttttaaa gttttatgtt gagttaagaa
    12361 atgagtttcg gttattgtca gaaaactaca accagtaaat gggaagaaga aaatcacaaa
    12421 aatcagtgtt caaacggtag cgacgatgtt ctgtttgaca ggtttatctc caaattttga
    12481 tgcgattgta ggaaaatatc caatctagaa gtggacctaa accaattaag agcgcgacca
    12541 tatttatcgc actcaactat atctattaga gaaactattt ttttattaat ttaatttacc
    12601 aaatgttctt acaaattcga tatattaatt ttattttgat atattatctt ttgtaatgat
    12661 acacccattt ctcaatgatt ttttgtaaag gggcttcaag tttatgcgta gataatgaat
    12721 tgaaagtatt aaatgacaaa agaaacgaag agaattttct catggataga caccagtatc
    12781 cactgtgtaa aatcaggttt ttttcatctc atatcgtatt ttatacagta atcgtgaggg
    12841 gttttatgat aaaatagcta ttgagactgt gaggtgatga acaatgaata tacaggatat
    12901 cgccaatcta gcgggcgttt ctaaaagtac agtttcaagg tatttaaatc aaggatcgat
    12961 tagtttaaaa acaaagcgaa aaattcaaca cgtcattgat acatacggtt atgaaccgaa
    13021 ccaatttgct caaagtttaa gagcacaaaa aagtatgatg attggtatta ttttcccgag
    13081 aatgtattct catgccgtgt ctcaaaccgt taaagggatt aaagcgaaat gtgacgcatt
    13141 tggctatcaa atgttgttaa atttaactga gcgtcatgtg gaacaggaac tagatgcgct
    13201 gaaatctttt aaaagaagta aagtggatgg cattttattt atggcgacta ctgtgacaga
    13261 tgcacatatg gctgtcattc aagaaattga taaaccagtc atcatcattg gccaagcaca
    13321 tgcatcgtta agctcggttt accacaatga ttatcaagct ggtcaactaa tgggacgaga
    13381 aattgtggca caagggaagc aacatgtcat ttatgcgagt attcaagaag atgacgtcgc
    13441 ggtcggtgag caacgttttc gaggtttgat tgaagtgtta accgcaaatc aggttacata
    13501 tgaaacattg atgacatcgt ttgattatga aaccgcactg caatcaatta aaggtcagct
    13561 tacccaacaa ccatctgtgg cgtacgtcgg tgcgacagat acgattgctt tggcgctcta
    13621 tcaagcgttg atgcacgacc atatgaccga accgccgtgg attgctggtt ttggcggaga
    13681 tcctatgaca caaattgttc atccaatgat ttttacccta ccttatcaat atgaagcggc
    13741 aggacgtatc gcatttgaac aattacagct tcaaatggaa cagccggacc ttattcaaag
    13801 ttgtcaactt gacgtgaatt ccaaattatg agggtttatc tcaaaagagg tggaaccgtt
    13861 accaatgtgt taaaaggagg tatatgatgg aacaatggag tagagaaaag cgttatcgta
    13921 agtatgaaga agcaacacat gaggaaatgg agttattaac ggccaaagtg aaccgctctc
    13981 catttcgaca aacctaccat attcagcccc caacaggatt attaaatgat ccaaacggtt
    14041 tgatcttttt taatggtcaa tattatatcg cacatcaatg gtttccacta ggtgccgtac
    14101 atggtttaaa atattggcgg ttactcacaa gcaacaatct cgtacagttt gaagatcgtg
    14161 gtgtcgtatt acgcccggat caaacgtttg atagtcacgg cgtctacagt gggagtgcat
    14221 tttcgtttca tcaaaagttg tattatatgt acacaggcag tcatcgtgac aatgagtgga
    14281 accgtcacag tagtcaaatc gtagcagaag tgcaagcaaa tgggtcagtc cgtaaactat
    14341 tacctccagc cattccggca cctcctcaag ggtatacaca acactttcgc gatcctaaag
    14401 tgtttgagaa agatgggaaa ctgtatacat tgctaggagc acaacgtgag aatgaaacag
    14461 ggtgtgccgt attatacgaa gctgaacgcc ctgaaggacc gtggcagttt aaaggtgaaa
    14521 ttcaaaccca attagaagat tttggttata tgtgggagtg tccagattat tttcaaattc
    14581 atggaaaaga tattttgcta ttctgtccac aaggcataga atctgaaggc gatgcgtatc
    14641 aaaacattta ccaaagcggt tacataatgg gaacgttaaa ttttgataca ttagaatttg
    14701 atcatggtcc gtttatcgaa cttgaccacg ggtttgattt ttatgcccct caaacgatga
    14761 ctgatgaagc ggggcgacgt gtgttaattg gttggatggg tctacctgac accgaatatc
    14821 cgacagatga tgacggttgg gcacactgtt taactttgcc aagaacatta acgattgaag
    14881 acggcaaatt aaaacaaaaa ccgcatatgc atttaagaaa gttacgtaaa aatgaagaag
    14941 ttgcgctcgg ttatgcgaac aaatttatta aacaactcca tccgtatgaa ggagtgcaat
    15001 atgagttggt cgttgatatt ttagaaaatg aggcttctgc gtttgaatta caactccgtg
    15061 catcacgcaa tgaatccaca acgattcggt atgatgcaac gacacgtcag gtttcactgg
    15121 agcgctttga tagtggggca ttaccgtatc cagttgaagg aacgatgagg gtgacgcaat
    15181 tacatacgga tttgaaacaa ttacgtattt tcgtggatac atcaagcatt gaaatctttt
    15241 gtaatgaagg ggaacgagtg ttgacgtcac gcattttccc taaagcgaca tcaaataagt
    15301 ttaaagtcgt cacagattcc ggtcaaattt atttgaaaat gactaaatac gatattgtgg
    15361 aaggaggata atgaatgaaa cgtttttatg caataggtga agcgctcatc gattttattc
    15421 ctacacaaag agagacgcca ttgaaagatg tgacagggtt tgaaccgcaa gtcggtggtg
    15481 caccgtgtaa tgtggctgct gctgttcaaa aattaggtgg caacagtcat ttgattacac
    15541 aagtgggtga agacgctttt ggtgacaaaa tcatcgagac gttacaagcg gttgaagtag
    15601 acatctcaca tattttaacg acaaaagaag cgaatacagc acttgcattt gtcagtttat
    15661 ctaatgatgg agaacgagac ttttcatttt accggaagcc gagtgcagac atgctatatg
    15721 aagctgaaaa tattgacaca attgagttgc aacaaggtga tttagtacat ttttgttcgg
    15781 tagcattagt tgacagtcct atgaaacgcg cacatgtgac attactggat aagtcggaac
    15841 aagtcggtgc gaccgttgtg tttgatccga atgtgcgctt acctttatgg gatgaccatg
    15901 atgtttatta cgagacattg caagcatttt taccacgtgc acatgttgtt aaagtttcag
    15961 atgaagaact gtcatttgtt acacgatatg aggatgaagc ggaagcgtta aaatcactgt
    16021 ttgtcggcaa cgtgcaagcg gtcatttaca caaaaggcag tcgcggagca tctttaattt
    16081 tcgaagatgg ctcaacaatt gaagtgccca caccgccagc gcaagtggtg gattcgacag
    16141 gagcaggcga tgcatttatc ggtgcaatca gtgcgaaatt atgtcaatcc gagcaacaac
    16201 caattgagac attacgccaa cacgggcatg atattttaaa atttgcacat caagtttcag
    16261 gtcgcgtcgt gtcccaatat ggcgccattt caagcttacc aacattagaa gaactttaat
    16321 taaaaagcca atctcccacc tatccgggaa attggctttt taatgcgata tatagctttt
    16381 aaatttggtt atatattttt aacggttggt gagagattca ctgaccgtta ttttaatttt
    16441 tgatattaaa aaagcacaaa tatctctata attgtaagtg accaaaccaa cgattaagga
    16501 gatattgtgc ctatgtgtaa tgatatatca gaaatactag gaattaaagt taaaaattta
    16561 aaaatcactc aaaatttagg attacatgtt cataaaaacg tacaggcatt attctatgaa
    16621 ggtcaattga cttatcatcc cagtgcttgt gagtgttgtg gaattaaaaa tgataaccat
    16681 ttaattatta aacatggctt tcgtaaaacg aatgtttata tggggttaat ttttgaaaga
    16741 cctgcctatt taaaattgaa gaaacagcgc ttttactgta aagcttgcca acgaaccttt
    16801 acagctgaaa cgccctatat tcaaccccga tgtaccatct caaatgaggt caaacgcatg
    16861 atgacctgga aactatcaaa agttacatct gaaaaagata tcgctgaaag tctatgtgta
    16921 tcgccttcaa ctgtccatcg ccatttaaaa gtagtaagta attcggtgaa gacacacgca
    16981 cattacgttt tacctgagca cttagctttt gacgaattca agtcgacgaa agatgtcgaa
    17041 ggtgcaatga gctttattta ctgtgatagt gtgactcatg atatcattga tattttacct
    17101 gatcgtcgca aacatcaatt agaagcttat tttttaaagt tctctagaaa acaacgtgaa
    17161 aaagtaaaaa cggtctctat agatatgttt ccaccttata tcgctctgat tcaggattta
    17221 tttcctcatg cggaaatcat tatcgatcgc tttcatatcg tacaagccat caatcgtgaa
    17281 atcaatcgct gccgtgttca agtcatgaat ggttttagga caaaagagcg acctcaatat
    17341 aataaattaa agcgttattg gaagttacta ttaaaagcgc ccattgattt agatcgaatg
    17401 atatatcagc catacagact ttttaagtca tggcagagcc agtacagttt agttcaatac
    17461 ctgttaaatc ttgatgagac gctcaaagag acatatgaaa caggacaccg tcttttaagt
    17521 gctttgaaag caaacgatat ccagcaacta cggttcatct tacaggatgc aaagacaaaa
    17581 gatatttcga aagggctcaa gcgtgtcatc cacacattca tcaaatacat gccttatatc
    17641 tcaagtacta tgcgtcatcg acatttaacg aatggaccca ttgaagggat taataataaa
    17701 ataaaactga ttaaacgtgt ttcttatggt tatagaaatt tctggaattt taggaatcgt
    17761 atcttaatga tttctaaggt atttgtaagt gaatataaaa aacacattaa acaacaaaat
    17821 aacgttgctt aatgcgttat tgtctcacca accgacgttg acaaagaacc ttaaattttc
    17881 ttcaaattac gcaccgacac gtaacaaaat tcttcatttt tgaaataagc aatccgttct
    17941 ttcgtatcga cacttgtaat atttcttctg tttagtacat aactgttgtg gcatctgaag
    18001 aatcgatcat cgagttgagc taactctttc aaattgccgt aaaattcgat ttgacgattg
    18061 tctaaatgcg cgattaaacg atgtgacttc ggtgaagact cgaaaaacat cacttcgtca
    18121 tagttcacgt aaaccgagct tgttccacgt ttgagttcca aagtttcaac agtatgatct
    18181 tttgttaata aatcaagccg ttttaatgct gtttctaaac aatcgataat gcgtgtcctt
    18241 aattcttcag gatcatcttt aaaaataaaa tccatggcag ccactttata gacaaacgtc
    18301 aagtacgtca gctcactatg actcgtcaca aaaataatat tcccaacagg atcgtgctta
    18361 cgaatttcgc tccctaattt aatcccgtta atatcagact ctaattgaat atctaaaaag
    18421 tagcagccaa tatcagtcat gtttttagaa gtttctaaga tagcataagg gtcattggta
    18481 gcaagctcaa ttttcatcgg cttctcttca atcataatat agttttcaat aatggacacc
    18541 atacgttcgc gttgtttagg atcatcctca caaatcaaaa ttttcatgat acacacatcc
    18601 ttattcataa tcgttcataa tctctagttt ttgaataaaa taatggtttt cgatcgtcgt
    18661 atcaaggaat acattgtccg tttgatcaat aatctctttt aatgttgtta atcctatacc
    18721 tcgattgttt cctttagttg aaaacccatc ctggaacaag gtatgtaact taggcatatc
    18781 ttttggcgct ttgttcataa taataatcat tacggacgca tccgtcttaa taaatgcgat
    18841 ttgaatgata ggatcctcta tcgtgttgga agcttctatc gcattatcca taataatacc
    18901 taacacacgg ctgagttgaa tcgcatccat atcaatttgc gtgatttcat ccgccacttc
    18961 aacagtgatt tcaatattat tttcttgcgc ttgtaaaatt ttagtcgtaa ttaagccttt
    19021 aatttcacgg acttttagat tctcaatacc attcagtcgc atcgtattgg attcaaattc
    19081 gctttttaaa ggactaatat gttcatgata atattgcttc aaaccttcta aatcatcttc
    19141 acgtaaatat tcggacatcg ttaataaaat attcgtatag tcatgtcgga atttacgcat
    19201 tttgttgtta attttttcaa tttgtactgt atatttataa taatcgtcta attcttgctt
    19261 tttccgttta taattgattt cgcgttctat tgttaaagtg gttgctataa ttaatatagc
    19321 gaaaaccgaa aaagaaataa aacaaatgat accaaaatat tgaaactcat agatatcacc
    19381 aactgatctt ggtaaaaaag agaaaaaaat gacaaatcca cacgctaaaa atacaacgag
    19441 agcgattaaa taaattttat taatatacag ccaagatgtt ttaagtttat taaacaatgt
    19501 aataataata taagaaaaaa ggcaacaacc tagcgcaaag accaccatat agattaatga
    19561 tgtcacataa aaattgatgt gatatgtatt aagatacgca aaaatccatg tcgcgatgaa
    19621 atcattaatc attaaaacaa gaattgtaag taacactgta ataattccaa tgatttttgc
    19681 tcgtctaaaa tagaagatga aaaagcaaag aattaaataa agcaaactgt atttatcgaa
    19741 aattaaatat aaaataatag aagggattac tatcccgagg atgagagtaa tgtaatccct
    19801 ttgactatat ttatattttt ggataatact tgttactgat gcgaaaataa aggattgaaa
    19861 taatactata aatatggcta aaagtatttc caattttata cacactttct aactttttat
    19921 ttgtcctctt ctaacaattc ggcagggatt tctggctcat caaaaaatcc agtactagta
    19981 gggattctag caaaagtacc gattgattgg aataaatttg taataaggtt gaataaaact
    20041 tctaaaattc tcatgttaaa cttcctcctt agtagaaaaa ataggtaata atgtgaatga
    20101 ttgtaataat accccataaa cgacaaagcg attataaggc gttggtacga tgaatgcaag
    20161 agtcatgagt ataatgaata caatgattga tttgatttta aggcctttca ctcttcttgg
    20221 agctatgggt ctttttttcg ttgcagcggg tgcatatttg attacgatca tcgcagccaa
    20281 tatactcaag cttaacaaaa attgaaacga aatgtcatat tgtactatta accatggtaa
    20341 aacaacgaat gaagcaatgt tttgtacatg acaaagcatt gaagttttcg cgtgtgcccc
    20401 atgagaataa gtcctcaagg caagaaaagt taggtgaaca atgagtgtgt ataaaaaaat
    20461 gtttaatagg agtgcaagcc cgtaagtcac aacagcttta aatgagttaa tcacgacaac
    20521 ttgcatgcct aaacgcactt ttaaaaactc aatatgactt aaattctgtc gttgttggag
    20581 cttcagcgcc attttttcaa ttccattgtc aataagtaac atacggctct cctccttgtc
    20641 taaattataa tacacaacta ttaaaacgct ttattttttg cctaactgtt catttatcat
    20701 tcctaactgt tgtgattggt tgttttttaa tattttacca taaattttta aacagttaag
    20761 cataaaaatc aacaacttac gcactggtta acacaaggac caaaaaacat gttgtaatat
    20821 agtcatcatc acattggtga tggagataaa gtgattttgt attaagtgtt gtcgagtaca
    20881 cttaagcaaa tttactgatt aagttaagtc agatgttctt agtcattgta ttcttcgctc
    20941 agcttacatg actaagggag caacaatcta ttggagtctt tgattttatt tataatttaa
    21001 ggaggtgctc actatggcag cagatatcat tagcacaatc gttgaatttg ttaaacttat
    21061 cgcagaaaca gtagcaaaat ttatcaaata ataagatttg ataaaagtat ttgttagaat
    21121 ctttttcctt acttagacta aagtaaaatc aggtttcgat attgaagcca ttgtagcaat
    21181 atttaataat cggtgaattc actaaatttt tcataattaa taacatcccc aattaaatag
    21241 aataactgta aataaaacat tcccttaata tgaagaacag gcgagtccct cccaagctcg
    21301 tctgttcatt tttatttgat gctcatgata aaaaaaggcg ttacttctct tgaataagag
    21361 aggtagcgcc tcatatttta tatttctttt tgtgcgtagc gatatacaga cggtcgcata
    21421 ttttcaaaaa ctggaatagc acggcgttgt gtgtctactt tttgaagatc taatgtgacg
    21481 gtcatcactg tttcattttc atctgcttca gcgattattt ctccatttgg atccactacc
    21541 attgaatgac ctgcatacgt tgttttacca tcatgaccac tgccattgac agcaaccaca
    21601 tacatatcgt tttcaacggc acgtgcttgt aataactgac gccaatgtgt gagtcgaact
    21661 tcgggccatt gtgcgacata aaacatcact tttgcgcctt gtgctgcagg gtaacgactc
    21721 aattctggaa agcgtaagtc ataacaaatg atttgagaaa cacttgtacc gtcagagagc
    21781 gaataaggat aggggacaga cttgccacag gttaaaaagt ctggttcatc taacatcggg
    21841 acaagatgaa ttttatcgta ttcataaatt ttttcgccac gtcgattgac ggcaaaggct
    21901 gtattgtata cggcaccttc ttttcggtta gaaacagatc ccgcaacaat gtccacttga
    21961 taattttgtg ctaatttttg tataaaagca taactttgtg ctaaatcttc atctgctaac
    22021 ttatctaatt gaggcaatgc atagccgtta ttccacattt caggcaagac tacgacatcc
    22081 gtttgatcat ctaaatgttg ttcaaataac gtagcgattt tttgttcgtt ttgacgtgaa
    22141 ttagcgattg cgacattaat ttgaaataat tgtatttgca tcgtcatcat cctcatttct
    22201 gaattaatct tagtgtacta aatgatgaac ggtttaacaa aaatcttaat tgaatacaat
    22261 catatataca tgagggtggt aatcgtagtc acttttgttt atactggctt tgttaaaaaa
    22321 ctttaaacaa tcagaggtga atctgatggt agaatataaa aaagaacata gcgtaaagcg
    22381 actattaaaa ttaggaatcg gttcaacgag tattttatgt gttgtatcac ctcttttatt
    22441 aacacatgac gttgttcaag cagcagatat caataacagg atgccagctt tgaatacatt
    22501 gaagaccact tcatcatatg atcaaagggc acacatggat gaattacgaa gcgccattac
    22561 ttcagatagt gacactactc aaacaccatc attcaatgag ataactgtgt cttcaactaa
    22621 tgaaacggat gcagcgtcaa cggaaaatgt gaacccgagt gatgaggtct cggcaaagga
    22681 tgaaagtgaa tcaacgacac cgagtacaga acaagataca tctatagaag aaacgggtac
    22741 tgaagaagtg ccatctcatg aagacaatca tcacaacacc ccaagtcaag aacagcaacc
    22801 gtctccgcct gatcaaccag gaacaaacaa agatgaagag agtggagaaa aaccgaataa
    22861 agaaaatcat cggaagccga atcaaccgaa caaagaccaa ccttcaaaag atgagaataa
    22921 aaaacctgac aaaggaaaca aaccagcacc accgtctaaa gcgccaaatc gcccggatca
    22981 aaaggaagag ggttcaaaca acaccccacc acctgccact gataacggtg gaaacagtaa
    23041 tgacggtaca acaacgggtc ccaatggtgg aggtggcagt gaagcaagtc caccaccgaa
    23101 tgagcaaccg tcaaatggca atgcaagcga tacccatcaa aacggttcag tttcaagcac
    23161 caatcattcg aatcagtatg gtacatcggc ttatgatgaa tacgcaggtt tattgaataa
    23221 taattataaa tataatccat tgtttaaaga agaggttgcg cgtttaagtc aatttggaag
    23281 tcaagaccaa catgatattg caagtttgag tcgtaaagaa caattttctc aaaatgcatt
    23341 tttagatgac ttgcaacaaa gtacagatta ttttagatat caatatttta acccgctttc
    23401 cacagagcaa tactatcatc gtttagataa acaagtacta gcactcgtta cgggggaatt
    23461 tggttcgatg ccagatttca agaaaagtgg tgataagtca ttggttaata agcatcagca
    23521 agataaagtg aagaaaattg aacagcaagg agaaaatatt aatacacatc atatgaaaaa
    23581 tacgaaagaa gatacaggaa aatcattaag ttacaagccg atgatttata ttggcattgt
    23641 catggtcggt tttgtcggcc tgatcagtat gattttatgg aaacgactgc atcatttttg
    23701 gaaataaatc aaaaaagggt taggccactt taactaaagt cgtcttaacc ctttgtacat
    23761 tgtaaaaaat aaatatgaag tatttaaaag taattttgtg aagcagaccg tgtatagttt
    23821 atgaaaggaa aaaagacatc caatgcgaag tcaataaaag aatgaattgt gtttgcttaa
    23881 cggcttcttc aatcattttt tcaggcatca tgagttgaat gagtgcaacc aaaccatttt
    23941 gagccatatg aataccaatc gacacactca aacgttttgt ataaatataa aatgccgaaa
    24001 agatgatacc catgacaaaa taagctaaga aatgtgaaaa atccatatgg acaacagcaa
    24061 atactgcaga actgatcgtc gttgcaatcg tgaatttgac ccattgattc gctttaattg
    24121 cgtgatacag ttcaccaaac aatacttttc taaagacaaa ctcttctaat aatggtccga
    24181 caatcgctat caacacaata aatattggca tttgacgagc gattttcatg attcttaacg
    24241 tattctcgct cgcaggatta gccccaaata gttggacaga aatgagattc acaaccattt
    24301 gtgcgataaa cacaatgact agacctacta atatataggg tagtacatag cgttttttct
    24361 cttttggacc aagttcaaag ttcaatttat ttttcacgaa caactgaagt atgatgatta
    24421 aaatggcgac aatgataaaa gcagtgaact gaactgctat cgattgccgc aacaattgtg
    24481 cttggttgcc tgtttgaatc cagccaaccg cacgtgcaat ataaggtgat atttgtgcaa
    24541 ggatgtatag tactacggtg agtagtgaaa cccaaaatct cttcataatt agcctccgtt
    24601 caatctcttt tattctaacg gaaaataaag gtatggacaa tggctttaaa ggtaaacgct
    24661 tgaaattttg accaattttg attattatag aattaaatta gcactcaata tatgaaagtg
    24721 ctaaattgat gttgaacata aggaggcact catacatgct tagaccatta ggaaatcgtg
    24781 tagtcatcga aaagaaagaa cacgaacaaa caacgaaaag tggtattgtt ttaactgatt
    24841 cagctaagga aaaatcaaat gaaggtgtta tcgttgcggt aggtccggga cgcattttag
    24901 acaatggtga acgtctcaaa cctgaactca acgaaggcga tcgtgttgtg tttcaacaat
    24961 atgcaggaac tgaagtgaaa cgtgacgaca aagaatactt agtgttaact gaagatgaag
    25021 tgttagctgt gattgaagac taatcaaaca ttgaatataa aacaaatgaa tccaacaacg
    25081 gaggtaatag aatggcaaag gaattaaaat tctctgaaga tgcacgtcaa gcaatgttac
    25141 gtggtgtcga taaattagca aatgctgtta aggtgacaat tggtccaaaa gggcgcaatg
    25201 tcgtacttga taaagaattt acagcaccgc ttattacgaa cgacggtgta acgatcgcaa
    25261 aagaaattga attagaagac ccttatgaaa atatgggtgc gaaactcgtt caagaagttg
    25321 cgaataaaac gaatgaaatt gcaggggacg gtacgacaac ggcgactgta cttgcacaag
    25381 caatgattca agaaggactt aaaaacgtga caagtggtgc aaacccagtc ggtatccgcc
    25441 aaggtattga taaagctgtg gcagtcgcaa ttgaatcatt acacaatatt tctcaaaaag
    25501 ttgaaaacaa agaagaaatt gcacaagtcg gcgcgatttc tgcagcagat gaagaagtgg
    25561 gtcgttacat ttctgaagca atggaaaaag ttggtaatga cggtgttatc tcaattgaag
    25621 aatcgaacgg ttttaacaca gaactagaag ttgttgaagg gatgcaattt gaccgtggtt
    25681 accaatcacc atacatggtg acagattctg acaaaatgat tgctgaatta gaaagaccat
    25741 acattttaat tactgacaag aaaatctctt cattccaaga cattttgcct ttattagaac
    25801 aaattgtaca atccaaccgt ccaattttaa tcgtagcgga cgaagtagaa ggcgatgcgt
    25861 taacaaacct tgtcttaaac cgtatgcgtg gtacatttac agcggttgca gttaaggcgc
    25921 ctggtttcgg tgatcgtcgt aaagcaatgt tagaagactt agcgattgta acaggtgcac
    25981 aagtgattac agatgattta ggtcttgaat taaaagaagc gactttagat atgttaggga
    26041 ctgcaaacaa agttgaagtg actaaagaca atacaacagt ggttgatgga gacggtgata
    26101 ctgcgaacat cgatgcacgt gtaggtcaat taaaagcaca aattgaagaa actgattctg
    26161 actttgatcg tgaaaaactg caagaacgtt tagcaaaatt agctggcggt gtagcagtca
    26221 ttaaagtcgg tgcggcatct gaaactgaat taaaagaacg taaattacgt attgaagatg
    26281 cattaaactc gacgcgtgca gcggtagaag aaggtatcgt tgctggtgga ggtacggcat
    26341 taatgaacat tttcaaagac gtccaagcaa tcgaagcgga aggtgacgaa gcaacaggtg
    26401 tgaacattgt attaaaagca ttgcaagcac cagtacgtca aattgctgaa aatgcaggtc
    26461 ttgaaggttc agtcatcgtt gaaagaatga aaaatgctga gccaggtatc ggttacaacg
    26521 ctgctacaga tgaatgggtg aatatgttag aagcaggtat cgtggatcca acaaaagtga
    26581 cgcgttctgc attacaacac gcagcaagtg ttgcggcaat gttcttaaca actgaagcgg
    26641 tagttgcaaa cattcctgaa gataaaggga atgatatgcc acaaatgggc ggcatgccag
    26701 ggatgatgta aaacagctta taaatgttga tttaatggca ttttataatt gtgaatgaca
    26761 tattaataac ataaaagatt tcaaaaagat aaaaatgccg tttaattcag atgaaccaaa
    26821 cggacattta aattcattct tttgaggcgt tttccttaag cgagcaaaac ttatgggaag
    26881 cgcccttttg tgtgaattga taatctcagc ataaatcttt aaagtcgtat ttttaaacaa
    26941 ctgtattagg taagcggcgc ataaataggg tgtcccagcc cctttcctac gattaaatat
    27001 ttaactgtct ttaatttcac ctttcaatca agtattaata aacaagaaat attcacatta
    27061 aaatccatgc attttcaaga gaagagtatc aatatatact tcataggtaa cagtggggga
    27121 cataacaatt tttaattgtc ttaccttgat atattttcat caaattgcct cattaataat
    27181 ctttttaaat tttcacaatt gatgtcatgg actcgcattt cctaggactt gcctcaactc
    27241 aattcagcta ttgacagtgt acactggtat gaagccgaat tggattttcg acagcatatg
    27301 atccctcagg agtctcgtcc attttagcaa tttgaattta aatactttga accaataaat
    27361 atattataca ataataaaat aaaaacatta aaaataccaa aattagtgag gataaaaatg
    27421 gcgaagtgtc acgtctttct acatcgataa ataatagaga attagattta gatactgtat
    27481 taactaatga tttcaaaaca ggagacatta atttatccgg ggaaatctct aatatagaag
    27541 aatctaaaca ggtagattat acaattgatt taacatatgc tgatgaaaaa gacatagctg
    27601 ggtttttaat agataattta actggcgagg aacatgaatt tgatacaaga ttggctgaag
    27661 cttctgccgc acctatagta gttgtggcgg taatggctgc taggtatggt atccagtggg
    27721 ctattaaaaa gtacggtaaa aaggcagtga gtaatgctat aaaatcaaat acgcataaag
    27781 tggcgaaagg aataaactct agccttctaa ctagtaaagg agtggatatc ggaaaattca
    27841 cacaaaaagt gagagggaaa aacccagtct atagagatcc taaaactgga tggtctattt
    27901 caaaaaataa agggcagcct catggaggat cttattggaa attgttggat aaaggtggta
    27961 caagaaaagc tactttaact aaagatggaa aaatacttcg taaatagggt gattgataaa
    28021 aatgagtaat attattagtt gtatggaagt aagtggttta aaattctctg aaggtgaaaa
    28081 tgctgttcat ttagatttaa gtgaaggcga ataccctttt ttagatgatg gaaaaagctt
    28141 taacaaagat tattttgcaa ggattcataa caatgcaatt caaattttac aagatttgtt
    28201 tcaacaaagt aatactattg atatagttct tttatattat ttatatgggg actcatttaa
    28261 aaaaactagg ttcaaagaaa agtttagtta tttcaataat aacgaaatac cagattttaa
    28321 agaatatatt aatgatgaag gcatccaatg ttatattttt tcttataaaa ataagaattt
    28381 gaaggattta aattataaaa aattagtgcg agcaatttcc aatcaagatt ttaagggttt
    28441 attcccaaca attaaccaaa aagacaatta cttagatata tatttaatgg atagtaaaag
    28501 aggcatatta tttcacttgt atgatgatag aggactgtgg ctatattttc taaataagca
    28561 gtcatataaa atctattctc aaaaatacag caacctcttg tttgatgtaa gtcatgaaat
    28621 ggattaaagt ttatttaaaa ttaataatac taattttatt atcggtattt atatatttga
    28681 attataattg caagtatgaa aaaagtaaaa tagcagttct agatacaggt gttgaaaaga
    28741 aagctattaa aagcaaagta atatctcgta attttactct tgacaataac tcgaatagcg
    28801 tacatgctaa taaagtttca aaaattatag aatatgaagc agatatagtt atttacgatg
    28861 ctaaagtttt gaaccgtcat ggtaacggaa gattggagga tactatatca gcacttgact
    28921 gggcaattaa aaataatgtc gatataataa atatgagtta tggctttact aaaaattatc
    28981 ctgaattaca tagaaaaata aaagaagctc atgaaaaagg cattattatt gtagctgcaa
    29041 acggtaacga catttttggt ggtaaagaat ttccagcttc ctataaagaa actatatcgg
    29101 ttggagtctt gaataaggaa ggttcaaagt ctgtctttaa ttctaacgat gatgctgacg
    29161 tattcatttc ggttgataat aaattgccta atagcggtga gaatacttct atggctacag
    29221 cttatgtatc taataaattg actaaactgt gcaataggaa cttgagaaac atggacaaag
    29281 atgaaatatt aaagttaatt aatgagttaa attaattaac aacgtataat aattatgttt
    29341 gcacaaaagt taaaaatacg aatcaatttt taacatttat gaggcaatta ggttattaag
    29401 tttgagatat gtgatgctag aatgacatca tactcgttat gatatagcct catcacactt
    29461 cataacaaaa taaaaaccac tttactaaat gatgtcacga catttggaaa gtggttttta
    29521 cgtattgtga aaatgtttac gattaccgct caggtttctc ataccatgat tttaaaaatg
    29581 tatacaagac ttccgtaaaa taatccaaat cttgaatgcg aattttttca ttcgttccat
    29641 gggcttcgtc gagttcacct ggtccatata aaatggttgg aatgccaaag tctgcggtcc
    29701 aaccgccatc tgttactgtt gtgctcattg tcgtttgaag cggtgcctgg tgtacgtctt
    29761 catgtgcttt agctaacatg tgaaatccag gatgagatgt cggtaaagtg aagcttggga
    29821 agatttcacc tttctcttca atcatggaag cgccacccca ttcgaattga agtggatttt
    29881 gactaagcca taaatcacta tcggcaattt tatttaaata cgtttcaatt tcttctataa
    29941 tggtggcgta actttcgtca ggcaaataat gcacggtaat ccataagcga cattggtcag
    30001 cgataaaagc aggatgacgc ccgccttcaa ttacagctgg attaatcgta ttggcgcctg
    30061 gtggcatgcc gggataagat ttcgtaactg cccaatgccg ttcgagttct tgtaaggctt
    30121 gtatgatttt tatcattttt tcaatcgcac tcgcaccatg acgaccacca cctgcgtgaa
    30181 tgatatgact gcgcgcaccg tcatggatcg tctcctcact ttgaattgtg atccatccgg
    30241 taatgacgcc gccttgtccc atcgcaatgt tattgcttgt atctaacaca agtgctaaat
    30301 cagcttttgg tgaatgttca caggcgactt ttgtacctgc ttcgccaact tcttcgccga
    30361 caacagagtg tacgataata tcgccttcag gttgtaagcc ttcttggtgc aagcgttcta
    30421 agttataaaa aagggcggac atgccacctt tcatatcagc aacgcctcta ccaaatagaa
    30481 aattatcttc tgcagtcagt tgaaaaggat tgaagcgcca aaattgttca tcttcaactt
    30541 ctgcaacatc gacatgtccg tttaaaatta gacgtgctgc ttctggattc cgtcctttta
    30601 aagtgccgac gacaatacag tc
//
