LOCUS       NZ_CP065920            41845 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus pseudintermedius strain SP_11306-1A chromosome,
            complete genome.
ACCESSION   NZ_CP065920
VERSION     NZ_CP065920.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2605463)
  AUTHORS   Byukusenge,M., Banovich,F., Li,L., Kuchipudi,S.V., Jayarao,B.M. and
            Naikare,H.K.
  TITLE     Complete genome sequences of Staphylococcus pseudintermedius strains
            isolated from canine superficial pyoderma lesions in Georgia, USA
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2605463)
  AUTHORS   Byukusenge,M., Banovich,F., Li,L., Kuchipudi,S.V., Jayarao,B.M. and
            Naikare,H.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2020) Veterinary and Biomedical Sciences,
            Pennsylvania State University, Wiley Ln, University Park, PA 16802,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 233x
            Sequencing Technology             :: Illumina & Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016126755.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 13:13:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,469
            CDSs (total)                      :: 2,387
            Genes (coding)                    :: 2,345
            CDSs (with protein)               :: 2,345
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 13 of 42
            Pseudo Genes (incomplete)         :: 29 of 42
            Pseudo Genes (internal stop)      :: 14 of 42
            Pseudo Genes (multiple problems)  :: 12 of 42
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:44:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 307963
            Orig. end                         :: 349808
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065920.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41845
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-v"
                     /region_number="1"
                     /rules="(APH and HopA1)"
                     /tool="antismash"
     cand_cluster    1..41845
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(APH and HopA1)"
                     /kind="single"
                     /product="lanthipeptide-class-v"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41845
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[20000:21845](+)"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21845
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="1"
     misc_feature    complement(392..405)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.69"
                     /tool="antismash"
     misc_feature    393..406
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
     gene            complement(589..1293)
                     /gene="hisA"
                     /locus_tag="JC281_RS01210"
                     /old_locus_tag="JC281_01210"
     CDS             complement(589..1293)
                     /EC_number="5.3.1.16"
                     /codon_start=1
                     /gene="hisA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168444.1"
                     /locus_tag="JC281_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01210"
                     /product="1-(5-phosphoribosyl)-5-((5-
                     phosphoribosylamino)methylideneamino)imidazole-4-
                     carboxamide isomerase"
                     /protein_id="WP_014612896.1"
                     /transl_table=11
                     /translation="MIKIWPAIDLIEGKSVRLTEGDYSTSEAMTRSAEDSIQFYNQFES
                     VDRIHIIDLIGAKAQRAIEMDYIQQLIQASDKPIEVGGGIRDEATLRRYFDSGVDYCIV
                     GTQAITNTAWLAEMSQLFPGKIYVSVDAYRTAIKINGWTEDAALDLFDYVAQIETFPLG
                     GVIYTDISKDGKLAGPNFEITAQLAQATSLPVVASGGIRDRQDLERLEASGVTAAIVGK
                     AANQSTFWEGLS"
     gene            complement(1286..1861)
                     /gene="hisH"
                     /locus_tag="JC281_RS01215"
                     /old_locus_tag="JC281_01215"
     CDS             complement(1286..1861)
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000635614.1"
                     /locus_tag="JC281_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01215"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="WP_014612897.1"
                     /transl_table=11
                     /translation="MIVIVDYGLGNILNVQRAVQHLGYDVVVSRDPAVIERAEQLILPG
                     VGHFKDAMQAIDRYELAPLLKRQQKPIIGICLGMQLLYAFSDEGHVPGLGFFEGHVRAI
                     DTPYTVPHLGWNQLKSDVPSLDKDVYYVHTYQAPMNDDVVAYTDYGTQIPGIVQRGPYI
                     GIQFHPEKSGNYGLDILAQALKGGWQHD"
     gene            complement(1858..2439)
                     /gene="hisB"
                     /locus_tag="JC281_RS01220"
                     /old_locus_tag="JC281_01220"
     CDS             complement(1858..2439)
                     /EC_number="4.2.1.19"
                     /GO_function="GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167083.1"
                     /locus_tag="JC281_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01220"
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="WP_110168493.1"
                     /transl_table=11
                     /translation="MTYQINRETKETKIAIELSEVQETSHIDTGVGFLDHMLTLLSFHS
                     GLYFNIHVDGDTWVDDHHTTEDIGIVLGQLLLQLTRDKKHFERYGQQYLPMDETLTRAV
                     VDISGRPYLNFNASFSKEKVGQFDTELVEEFFRALVINARLTVHIDLLHQGNTHHEIES
                     VFKAFARALKQALRPSQEARIPSSKGVIES"
     gene            complement(2423..3436)
                     /locus_tag="JC281_RS01225"
                     /old_locus_tag="JC281_01225"
     CDS             complement(2423..3436)
                     /EC_number="2.6.1.9"
                     /GO_function="GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (23-277). E-value:
                     3.6e-36. Score: 116.9. Matches aSDomain:
                     nrpspksdomains_JC281_RS01225_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167084.1"
                     /locus_tag="JC281_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01225"
                     /product="histidinol-phosphate transaminase"
                     /protein_id="WP_198456143.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-34, bitscore:
                     116.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRMNKNESPIKPLSTETLTELIEKCDYHLYPDVAYDRFRKAYAQ
                     YYGSTFTREQITCGNGSDELIQKLMLIMPDGPCLTLNPDFFMYQDYARQVNRDIQFVDA
                     TSELSFPVEAVLDKIEAVQPSFFILSNPHNPTGHRFDESYLLAVANRMKQLGGYLVIDE
                     AYIDFSTPLDIALEDHILVMRTLSKAYAMAGLRLGVLIGTEKTIQLVRQIEHPYPLSAL
                     TMAIGIQLFENQADTEAFIAHQRHLSSRLKAILQQYASPHMTIYPSETNFVLTAGPQAM
                     VLGRHVEQHGFLPRFYNDPSEATMAGFVRYSIATEAQLDRFEQVVKEWSERHDISN"
     aSDomain        complement(2606..3367)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JC281_RS01225_Aminotran_1_2.1"
                     /evalue="3.60E-36"
                     /label="JC281_RS01225_Aminotran_1_2.1"
                     /locus_tag="JC281_RS01225"
                     /protein_end="277"
                     /protein_start="23"
                     /score="116.9"
                     /tool="antismash"
                     /translation="EKCDYHLYPDVAYDRFRKAYAQYYGSTFTREQITCGNGSDELIQK
                     LMLIMPDGPCLTLNPDFFMYQDYARQVNRDIQFVDATSELSFPVEAVLDKIEAVQPSFF
                     ILSNPHNPTGHRFDESYLLAVANRMKQLGGYLVIDEAYIDFSTPLDIALEDHILVMRTL
                     SKAYAMAGLRLGVLIGTEKTIQLVRQIEHPYPLSALTMAIGIQLFENQADTEAFIAHQR
                     HLSSRLKAILQQYASPHMTIYPSETNFVLTAG"
     gene            complement(3433..4692)
                     /gene="hisD"
                     /locus_tag="JC281_RS01230"
                     /old_locus_tag="JC281_01230"
     CDS             complement(3433..4692)
                     /EC_number="1.1.1.23"
                     /codon_start=1
                     /gene="hisD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612900.1"
                     /locus_tag="JC281_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01230"
                     /product="histidinol dehydrogenase"
                     /protein_id="WP_020219440.1"
                     /transl_table=11
                     /translation="MIVNSQTFLQQFETTETFNPEIHAQVTAICERVRREGDLALHDYN
                     QQFDGIKVEALEVPQADIAAAYHNIDEDLRHALEHSFRRIRDYQTQIKYENQYATPELY
                     EVYHPIERVGIYVPGGKASYPSTVLMTATLAKVAGVKNISVVTPPQQNGVAPSVLAACH
                     IAGVDHVYQVGGAQSIAALAYGTETIPKVDKIVGPGNQYVAYAKKALYGEVGIDQIAGP
                     SEIALIIDDTCNLEAVVYDVFAQAEHDEMARTFVISTDLALLESLESRIQQTLNGAPRH
                     DILKVSLKDNHYLIHATDFEDSCHVMNTIAPEHASIQTAQPENYLPHIHYVGSLFLGGY
                     APEAIGDYIAGPSHVLPTQRTARFQHGLSVNDFLTKHTVIHLSEATYEKTYRDAARIAQ
                     DEQLYHHQKSLEIRQRGDNA"
     gene            complement(4682..5296)
                     /gene="hisG"
                     /locus_tag="JC281_RS01235"
                     /old_locus_tag="JC281_01235"
     CDS             complement(4682..5296)
                     /EC_number="2.4.2.17"
                     /GO_function="GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729680.1"
                     /locus_tag="JC281_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01235"
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="WP_014612901.1"
                     /transl_table=11
                     /translation="MLTIALAKGRLLKSFIAYLESQGQNDLAAQLKSRERQLQIKVSPF
                     HFLFVKGNDVPIYVEQGIADIGITGSDILNEAQYDVNQLLALPFGQCHFSVAAFDETTD
                     YHKVATSFPKTARDYFKATGRDVELIELSGSIELACVIGMVDGIVDIVQTGTTLRSNGL
                     VEKEHITDIQAQLITNRQSFFTQSSEIDAFINMLGVSLIDR"
     gene            complement(5312..6121)
                     /locus_tag="JC281_RS01240"
                     /old_locus_tag="JC281_01240"
     CDS             complement(5312..6121)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612902.1"
                     /locus_tag="JC281_RS01240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01240"
                     /product="ATP phosphoribosyltransferase regulatory subunit"
                     /protein_id="WP_105503067.1"
                     /transl_table=11
                     /translation="MGQPFIQNKQYEIDFLKLATANDFEPIETAFIETLVWDELSPDDL
                     KQMKERSVWQADDTLFALRNDFTDQLVRYYQHYQLNHSAVAYTGPIVRHHQVQTQLGLE
                     CYRPHIQEMYHAFETFQQFISQHLQDEIQYVVIGHYQLIDLLLEHQAEREQLLTWVEQR
                     NISALKSALGMSHPLVRLLLTPTHQQLELLNALYPHDHVIIRSLNRWQTYFKSLHIDTI
                     HLDITPQAPRSYYKETFIHAHLQNSGRTLSGGYYNGPLEGFGLGLTL"
     misc_feature    6210..6224
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.9"
                     /tool="antismash"
     gene            6452..7114
                     /gene="deoC"
                     /locus_tag="JC281_RS01245"
                     /old_locus_tag="JC281_01245"
     CDS             6452..7114
                     /EC_number="4.1.2.4"
                     /GO_function="GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="deoC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498700.1"
                     /locus_tag="JC281_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01245"
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="WP_014612903.1"
                     /transl_table=11
                     /translation="MNFEKYIDHTLLKPESTRAQIDKIIEEAKAYHFKSICINPTHIAY
                     AAEKLADSDVLVCTVIGFPLGANTTETKVFETEDAIRKGADEIDMVINIGALKDQRYDD
                     VQKDIEAVVKAAEGKTVKVIIETALLTEEEKVKASELTKAAGAHFVKTSTGFSTGGATP
                     EDVKLMKDTVGESVEVKAAGGVRNLEDFKAMIDAGATRIGASAGVQIMQGLEVDSDY"
     gene            7148..8326
                     /gene="deoB"
                     /locus_tag="JC281_RS01250"
                     /old_locus_tag="JC281_01250"
     CDS             7148..8326
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="deoB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498701.1"
                     /locus_tag="JC281_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01250"
                     /product="phosphopentomutase"
                     /protein_id="WP_014612904.1"
                     /transl_table=11
                     /translation="MTVPFQRVHLIVMDSVGIGEGPDAKDFNDEGSHTLKHTLEGFDQK
                     LPNLEKLGLGNIAPLPVIDAVDHPLAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFKVY
                     PEGFPEELVQEIEQLSGRKVVANRPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQIAA
                     HEDVIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALKPFGK
                     TVMNTLKENDYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMNIVNKDFKGLSFLN
                     LVDFDALYGHRRDKPGYAQAIKEFDNRLPELMDALHEDDLLIITADHGNDPTAPGTDHT
                     REYIPVIMYSPKFKGGQALEGDTTFSSIGATIADNFGVTLPEFGRSYLNELK"
     misc_feature    complement(7167..7178)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     gene            8801..10552
                     /locus_tag="JC281_RS01255"
                     /old_locus_tag="JC281_01255"
     CDS             8801..10552
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166488.1"
                     /locus_tag="JC281_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01255"
                     /product="sensor histidine kinase"
                     /protein_id="WP_065353991.1"
                     /transl_table=11
                     /translation="MFNLTILLLERVGLIIILAYILMNSKYFKHTMQQRQAWASKWQLC
                     IVFSLFALLSNFTGIVIKNGDILAGSIYFQLDDNVSLANTRVLTIGVAGLVGGPFVSVF
                     VGILSGIFRLYMGGAEAYTYLISSLFIGLISGYYGRQALEQHQYPTIAKSALIGGMMEI
                     VQMICIFSFAQDKQYAMDLIALIGLPMIVVNSAGTAIFMSIISSTLKQEEQMRAVQTHD
                     VLELTNQTLPYFKEGLNEDSAKHVAMIIKDLMKVSAVAITNRHDILAHVGAGSDHHIPK
                     KEIITHLSKAVLQTGELKEVHTKEEIGCTHPHCPLHAALVIPLKMHGKVTGTLKMYFTN
                     PTNLTFVERQLAEGLAEIFSSQIELGEAEMQSKLLKDAEIKSLQAQVNPHFFFNAMNTI
                     SALVRIDSEKARELLLELSHFFRSNLQGSRQNTITLEKELSQVTAYLSLEQARFPGRFD
                     VTFDVPQKVQQASVPPFLIQILVENAVKHAFPNRKKGNTIKVGARLKDAQQLYIEVSDN
                     GRGIPPDKLTQLGQKVVESESGTGSALENLNLRLKGLFSEQAALHFDSDDTGTCVWCTL
                     PYQQKED"
     gene            10556..11290
                     /locus_tag="JC281_RS01260"
                     /old_locus_tag="JC281_01260"
     CDS             10556..11290
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612907.1"
                     /locus_tag="JC281_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01260"
                     /product="response regulator transcription factor LytR"
                     /protein_id="WP_014612907.1"
                     /transl_table=11
                     /translation="MRALIVDDEPLARNELIYLLNRIGGFDVLDEAENVSETIEALLVN
                     EYDLVFLDINLMNENGIELGKKIQKMKAPPAIVFATAHDQFAVQAFELNATDYIMKPFD
                     QSRIAQAVAKVRAQQEKYEDMHVPHSAVKVTQPLPIEIGERIHMLNPVDVIGISVNQGV
                     TTIYTTQGEYETHEPLSAYEKRLDEAQFIRIHRSNVINRQHIEAIEHWFNSTYMVTLTD
                     GVKMQVSRSYMKKFKQAMGLKL"
     misc_feature    complement(11766..11781)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 20.43"
                     /tool="antismash"
     gene            12092..12526
                     /gene="lrgA"
                     /locus_tag="JC281_RS01265"
                     /old_locus_tag="JC281_01265"
     CDS             12092..12526
                     /codon_start=1
                     /gene="lrgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612908.1"
                     /locus_tag="JC281_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01265"
                     /product="antiholin-like murein hydrolase modulator LrgA"
                     /protein_id="WP_014612908.1"
                     /transl_table=11
                     /translation="MKQKEEKTYSFLHQVLVIASVLFVSSIIESFMPIPMPASVIGLVL
                     LFVLLCTGVIKLGQVEKVGTALTNNIGFLFVPAGISVVNSLDIISASPILIIGLIIIST
                     ILLLVFTGFASQILMRMTTKDKVATPPRTKAKVKGAHSHG"
     gene            12519..13220
                     /gene="lrgB"
                     /locus_tag="JC281_RS01270"
                     /old_locus_tag="JC281_01270"
     CDS             12519..13220
                     /codon_start=1
                     /gene="lrgB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498828.1"
                     /locus_tag="JC281_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01270"
                     /product="antiholin-like protein LrgB"
                     /protein_id="WP_014612909.1"
                     /transl_table=11
                     /translation="MVNHLAIDTPYFGILLSVIPFLIATVLFKKTNGFFLFAPLFVAMV
                     FGVAFLHFTGIPYEKYKIGGDIINFFLGPATISFAIPLYKKRDVLVKHWHRIIGGIGIG
                     TVLALVGIFFVAKALQFGSDIIASMLPQAATTAIALPVSEGIGGIKELTSLAVILNAVI
                     IYALGNKLLKWFHIDDPIARGLSLGTSGHTLGVAAAKELGPVEESMASIAIVLVGVVVV
                     AVVPILTLIFF"
     gene            13387..14349
                     /gene="dhaK"
                     /locus_tag="JC281_RS01275"
                     /old_locus_tag="JC281_01275"
     CDS             13387..14349
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0004371 - glycerone kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020361079.1"
                     /locus_tag="JC281_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01275"
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="WP_096533816.1"
                     /transl_table=11
                     /translation="MKKLIQDKTHFLQDMLDGLKITNPNIDVIADTVVVRQHKKTSGVA
                     LVSGGGSGHEPAHAGYVGEGMLDAAVCGEVFTSPTPDKVLEAIKAVDNGDGVLLIVKNY
                     AGDVMNFEMAKDMAAMEDIQVEMVVVGDDIAIDDVEKRRGVAGTVFVHKYAGYLSERGK
                     KLTELKTEVEALIDQIRTIGMALTPPAVPTTGKYGFDIEESEMEIGIGIHGERGLERVP
                     VEPVEQIVQRLIEQLKAEVASDELIVMVNGMGGTPLSELDIVTKYVALQLEQEGKTVKG
                     WFVGDYMTSLDMQGFSLTFVPYDEHILSAFRAPTTSRFF"
     gene            14372..14953
                     /gene="dhaL"
                     /locus_tag="JC281_RS01280"
                     /old_locus_tag="JC281_01280"
     CDS             14372..14953
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166492.1"
                     /locus_tag="JC281_RS01280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01280"
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="WP_014612911.1"
                     /transl_table=11
                     /translation="MDVATLKERLLALKETFETEEEALTELDRAIGDGDHGVNMRRGFE
                     ALPDQLDDSSMQALFKTTGMTLMSKVGGASGPLYGFSFVKMAQVANDEIDHDNLVELLK
                     AFEEAVAQRGKVTLNEKTMYDVIARAREAVEQGETVDLATLQSYADATRDIEATKGRAS
                     YFKKDSIGYIDPGAQSSVYILNALIGADEA"
     gene            14950..15309
                     /gene="dhaM"
                     /locus_tag="JC281_RS01285"
                     /old_locus_tag="JC281_01285"
     CDS             14950..15309
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124171.1"
                     /locus_tag="JC281_RS01285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01285"
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="WP_014612912.1"
                     /transl_table=11
                     /translation="MTQIVLVSHSDKIAEGTQELLAQMAQDVNVVAIGGIEGEIGTSFD
                     DISAVLNDINDDAICFFDIGSSEMNLDMAIEMYTGTHRIEKVDAPIVEGSFIAAVALST
                     GQTIDEAIASVDEAF"
     gene            complement(15376..15726)
                     /locus_tag="JC281_RS01290"
                     /old_locus_tag="JC281_01290"
     CDS             complement(15376..15726)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729673.1"
                     /locus_tag="JC281_RS01290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01290"
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="WP_015729673.1"
                     /transl_table=11
                     /translation="MTTAIPNCPQCDSEYTYEDGGLYICPMCAYEWTNDTLEAAAEQAV
                     IRDANGNPLQDGDTVSVIRDLKIKGSSQMIKQGTKVKNIKLVDPEDGHDIDCKIPGFGQ
                     IGLKSEVVKKIK"
     gene            15879..17267
                     /locus_tag="JC281_RS01295"
                     /old_locus_tag="JC281_01295"
     CDS             15879..17267
                     /EC_number="1.2.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729672.1"
                     /locus_tag="JC281_RS01295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01295"
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_014612914.1"
                     /sec_met_domain="Aldedh (E-value: 8.3e-163, bitscore:
                     539.3, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKFDVENPSTGEVIKTYAFTEEAEIHHKIERAYEAYLSWREVDA
                     HERSRLLWQWSTLIKENREALAELITLEGGKPYQEALGEVDYAVGYVDWYAEEVKRIYG
                     RTIPANSPDKKILVDKFPVGVVGAITPWNFPAAMITRKMAPALAAGCTIVCKPATQTPM
                     TTIRLVELAHEAGIPEDAISYILASGKTAGKIFTEHELINKVTFTGSTPVGKKLIEQSA
                     ASVKNVTMELGGLAPLIVHKDADIEHAVEQTIKTKFRNAGQTCICANRIYVHEDIAEEY
                     EKQLIEQVHALKVGDGMEKDVKIGPLINQKGVDKVLDHIQDAVEHGGQLSRELDDIQAL
                     GGNFLKPVVITNVNHDMKCMHEETFGPVAPVMRFADIDEAIHLANDTEFGLASYFFTND
                     YRTGLYIYNNLHYGVVGWNDGAPSAPHAPFGGVKESGYGREGGIEGIEPYLETKYLSIG
                     TKTN"
     gene            complement(<17760..18144)
                     /locus_tag="JC281_RS01300"
                     /old_locus_tag="JC281_01300"
                     /pseudo=""
     CDS             complement(<17760..18144)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500456.1"
                     /locus_tag="JC281_RS01300"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="JC281_01300"
                     /product="DUF1828 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MATFDANKLKKNIMIGTTKN"
     gene            18626..18787
                     /locus_tag="JC281_RS01305"
                     /old_locus_tag="JC281_01305"
     CDS             18626..18787
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444967.1"
                     /locus_tag="JC281_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01305"
                     /product="signal protein"
                     /protein_id="WP_096547175.1"
                     /transl_table=11
                     /translation="MKDLLFNGYSNYTTANNIQKCAVEECELGNVGTSISLSVTYSASV
                     SWTITWSV"
     gene            18844..19950
                     /locus_tag="JC281_RS01310"
                     /old_locus_tag="JC281_01310"
     CDS             18844..19950
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024748.4"
                     /locus_tag="JC281_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01310"
                     /product="serine hydrolase"
                     /protein_id="WP_198456144.1"
                     /transl_table=11
                     /translation="MLNVHIEFLKLINSTDKSDIKSEIRKIISKKKSEKDIKNLENLII
                     SLRVGNTKYIWNEERNEIVLNEKNISGCIKMYLDEENLLDRFFILPTIPEMTNIKDFER
                     AIKQINVDYEIQLVRKKDLLKVQSEANRNTPLAISSMVKIIVAACIYKEISEGNIELSS
                     TIKIKAEDISVLSAGIGKQNIGDLFTIEELLKLLLFVSDNTAMDIFIDYLGEDKIEKFL
                     NFEKSKVENKGYKFNFPLTKNIYTEAWCTESNSEQQWRNSAMKKVVWTEGLDYFIDLDY
                     VRYSMNYLLNNSWIPWDDIQNNNVIYKGGSAPGVLSCIWSTRNLEKEDFLQFLFVINKR
                     APFSLLEELYIFGCANKLLDFYGVLKVR"
     gene            20001..20957
                     /locus_tag="JC281_RS01315"
                     /old_locus_tag="JC281_01315"
     CDS             20001..20957
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: APH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444965.1"
                     /locus_tag="JC281_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01315"
                     /product="phosphotransferase"
                     /protein_id="WP_201800448.1"
                     /sec_met_domain="APH (E-value: 3e-08, bitscore: 31.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVREGRNINKKVEKGGKCLFKKTLVGPKSDAQRRFDNCLKWEES
                     RKNMPQINSPKLVDYDNDELDLYYEWLEEGTSLEDFLLEKSDDLENKIKVASNALAIIH
                     TTSNWISDIDKEKSLPDRRSLMIAISKYDYASCTGAELELFALLHQDKKFIESLFDENN
                     ETDECLCHGDVRLDQFIWYQNKMYIIDFEELRIGDGTRDLAGIIGSIYFNCLLKTFSET
                     TQETSDEKEIEAQFIERGMAYIEEMIPIMKSAYEAYSIVKPINLMNLSINIGWFIIERI
                     MSRAKYSFKLSATDKAILGIGREIILSPNKFEEIFKQ"
     gene            20976..21845
                     /locus_tag="JC281_RS01320"
                     /old_locus_tag="JC281_01320"
     CDS             20976..21845
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: HopA1"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016898474.1"
                     /locus_tag="JC281_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01320"
                     /product="T3SS effector HopA1 family protein"
                     /protein_id="WP_099986861.1"
                     /sec_met_domain="HopA1 (E-value: 1.8e-31, bitscore: 106.3,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHNTSIETLLTKMNLEIDLNKVTIANFIYKGVLEKPKAELIQWL
                     YKVLHTGNIEVNKNQIIKSLNDLDSNIIKRLKDPEIKMPVQKQEVHNKSYPIIHGVRIH
                     EDVGIDQFISVPCFRPNLTPGFFMFVNTENGLHNGNVKRHYIYADTPEYGIETWVNCVE
                     KLMSEKASFSAKVLSSSANYPRNDALVFYSSKDTQKVQEILVNEINKNPIRNIKGSLLA
                     KKLVHNLYVADEPIQRQGMHQSFGEHRCNAIADAIQDHFITGVEFKLLLKQRLLSYNIN
                     IDDISKNY"
     misc_feature    21989..22002
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.28"
                     /tool="antismash"
     gene            22063..22947
                     /locus_tag="JC281_RS01325"
                     /old_locus_tag="JC281_01325"
     CDS             22063..22947
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="JC281_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01325"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_099986865.1"
                     /transl_table=11
                     /translation="MVTSLIHVNNLSIHFGDFIALEDITLTFKKTNGVIGLIGPNGAGK
                     TTLISAIIGQLKFHKGFVNVNHEDVAYCPDVPSFESFLTPKEVLEQTIRLRGKPVKNYK
                     KKILDVLKDVDLTKSQNKLVGGFSRGMRQRLGIASALVLDPKIIFLDEPTSALDPFGQK
                     DVLQLVDKVAKNHVVVISSHNLKDVEKIAKEIIVLNEGRLIYKGNLNSFAEEKQKLAII
                     EFSDSKISENFDVILQENNISHSLVDKTIKFENYEIKKVLSLVNSYADYIVRIEREIFS
                     LEDAFEAHVKKSQ"
     gene            22966..23715
                     /locus_tag="JC281_RS01330"
                     /old_locus_tag="JC281_01330"
     CDS             22966..23715
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JC281_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JC281_01330"
                     /product="hypothetical protein"
                     /protein_id="WP_099986867.1"
                     /transl_table=11
                     /translation="MVKLELMTWIRSKKFLVIFVVFLFSGFTSPLIAYYSNDIINSFSN
                     SNTKIIFADPKWTDLILSYFKNASQLVMFITAYIIGDTCRFGKDKSIQLYYKTRARNSG
                     RILYPKILVSLVVVTLGALLGSLSALYTTWIYFDDFNLNHAVQGLFVQIIGILIFSTFS
                     GVIAFWINSAFVAALIVEIFIFIAMFFASIEEFQKWSPVTLLKPQNVLIEGINTTNLWY
                     PLIIGGLVCLILIIVSFYRPLRRKTIK"
     gene            23727..24668
                     /locus_tag="JC281_RS01335"
                     /old_locus_tag="JC281_01335"
     CDS             23727..24668
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169152.1"
                     /locus_tag="JC281_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01335"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_099986871.1"
                     /transl_table=11
                     /translation="MIAKVTNVQKSLNDREIIKNVSFSLEKGSINAILGPNGVGKTTTV
                     RLLTGLLIPTKGTVEVFGTLTTDKDFDRVREFIGVQNDGNLYESLTVYENLRLWAIFYN
                     IPSIQIPERIDKLLHHFDLHERKYSKVGTLSKGLKQKVSIIRAMLHNPKLLILDEPTSG
                     LDPSAAEELIRYIQKIVYEKNTTVFMCTHQLQGLENIADNIFIMYNGEFIVSGNSSELL
                     SSEWPGSTFEIVSNNPLKCLELLKGFSEVIIASEAYDEDVVRVSVKEKAMISKIIEMLV
                     YERINIYEVTKVEREIKEFYFKKIGEVKHGEY"
     gene            24655..25467
                     /locus_tag="JC281_RS01340"
                     /old_locus_tag="JC281_01340"
     CDS             24655..25467
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014304636.1"
                     /locus_tag="JC281_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01340"
                     /product="ABC transporter permease"
                     /protein_id="WP_099986873.1"
                     /transl_table=11
                     /translation="MVNIKYVCNIVRKDILEAKGEQGIIVSVLVIPFIFSILLPLLVIV
                     GGTNNTLVNFIGGIHIFIEQLPNDIFPINISKNNAIIYAVLMYFFIPFFLLIPVIVSTI
                     LSTSSFTGEREKKTIEGLLYTPITNKELMLGKILSSFLPAIIVTWISITVFGVIINLFS
                     INTMEKLVFPNLNWIIIGGLIAPLITFLSISLVIAISHKMKTSKSAQSVSMLLILPIIG
                     FLISQASGLFLFGTKISLILVSVLIVLDFSIYLIIAKKFNRDRFITKV"
     gene            25482..26600
                     /locus_tag="JC281_RS01345"
                     /old_locus_tag="JC281_01345"
     CDS             25482..26600
                     /NRPS_PKS="Domain: PKS_ER (45-298). E-value: 2.8e-14.
                     Score: 44.9. Matches aSDomain:
                     nrpspksdomains_JC281_RS01345_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016898475.1"
                     /locus_tag="JC281_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01345"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_099986875.1"
                     /transl_table=11
                     /translation="MKVLTIVNTDLVSEKDVEMLPDISIAGSKIKCGIIDIPKPTFNEC
                     EKENDHFVLVKVLAFSCNYRDKAIILKSALKMQGALNFQAAPFAFFGSDFVATVVAKGK
                     LVGNFEIGQRVIPNCAYPESPFPGVAAGVVTNEASKGWLRIHKSKLIAIPDNMDDAIAA
                     SFSIGGQTSTSMVRKVDLKKGERVLVLSGRSNTSMFIINNLLEKNVDTTVLTTSSWSKD
                     EISLISPAKLVKVEKSFLKWKDHEDLGTFDVVFDPFFDLHLEKAVNSLKTYGRYITCGY
                     KNQHNKFMEDTDKFNNNNLKSIILKVMINNMSIIGNCIGTSEDLEKALANYNPSRFIVP
                     IDGCYSVEEGDKFVARTYNNRGRLGKAVLAYS"
     aSDomain        25617..26375
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JC281_RS01345_PKS_ER.1"
                     /evalue="2.80E-14"
                     /label="JC281_RS01345_PKS_ER.1"
                     /locus_tag="JC281_RS01345"
                     /protein_end="298"
                     /protein_start="45"
                     /score="44.9"
                     /tool="antismash"
                     /translation="EKENDHFVLVKVLAFSCNYRDKAIILKSALKMQGALNFQAAPFAF
                     FGSDFVATVVAKGKLVGNFEIGQRVIPNCAYPESPFPGVAAGVVTNEASKGWLRIHKSK
                     LIAIPDNMDDAIAASFSIGGQTSTSMVRKVDLKKGERVLVLSGRSNTSMFIINNLLEKN
                     VDTTVLTTSSWSKDEISLISPAKLVKVEKSFLKWKDHEDLGTFDVVFDPFFDLHLEKAV
                     NSLKTYGRYITCGYKNQHNKFMEDTDKFNNN"
     misc_feature    complement(26665..26679)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.26"
                     /tool="antismash"
     gene            27391..27621
                     /locus_tag="JC281_RS12375"
     CDS             27391..27621
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013828.4"
                     /locus_tag="JC281_RS12375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_233510329.1"
                     /transl_table=11
                     /translation="MTEKEVEYQVKKTFKRAIKLARFPKVKYLSDFDFKLQPSISKQEI
                     LTLKSIHFLEKHINTCFLSNSGVGKTRLQYR"
     gene            27785..28026
                     /locus_tag="JC281_RS12380"
                     /pseudo=""
     CDS             27785..28026
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013828.4"
                     /locus_tag="JC281_RS12380"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSKERADLSYQLMSLRYEMKSTIITTDIPFLVGKIHLVTK"
     misc_feature    28095..28112
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 18.97"
                     /tool="antismash"
     gene            28142..28444
                     /locus_tag="JC281_RS01355"
                     /old_locus_tag="JC281_01355"
     CDS             28142..28444
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729671.1"
                     /locus_tag="JC281_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01355"
                     /product="hypothetical protein"
                     /protein_id="WP_015729671.1"
                     /transl_table=11
                     /translation="MIILLAILGFLFILLLVIHMFKLDVLIANIDFEQIDERYRDTVRR
                     RWLIWTEMMIAILFVWSLGFYLYHFYTVVFIIGVFCWVIIYSIGLHYLTKKFKNR"
     misc_feature    complement(28462..28477)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.51"
                     /tool="antismash"
     misc_feature    28465..28480
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 26.42"
                     /tool="antismash"
     misc_feature    complement(28468..28483)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            28615..28944
                     /locus_tag="JC281_RS01360"
                     /old_locus_tag="JC281_01360"
     CDS             28615..28944
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612916.1"
                     /locus_tag="JC281_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01360"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_015729670.1"
                     /transl_table=11
                     /translation="MFMAENKLTLQKGTAEATMKRFHRRQGIETIDGFIEMYVTQTNGL
                     KEYDEVKILTVWQSEAAFREWLGSDVFKASHKNVRQHHEEKESPILKNKVSTYQIGYHY
                     EKAHA"
     gene            29570..30535
                     /locus_tag="JC281_RS01365"
                     /old_locus_tag="JC281_01365"
     CDS             29570..30535
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (35-304). E-value:
                     8.7e-20. Score: 63.3. Matches aSDomain:
                     nrpspksdomains_JC281_RS01365_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612917.1"
                     /locus_tag="JC281_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01365"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_198456145.1"
                     /sec_met_domain="PF00561 (E-value: 3.6e-18, bitscore: 63.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.1e-10, bitscore:
                     37.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTYIERDGRTIQKHYLTLNGHRQGIIIESRGTAKPILLVVHGGP
                     GFPLYSFFRAHHIDLTDRYTVVFWDQRGTGMSYTRETVEMADLISDSYQLIQFLRHHFQ
                     QEQVYLMCHSFGTIIGTHLAHRYPEYIAAYIGMGQLGDVFHNEQCILQHLRFLAYEERN
                     QRAIKRLSAIHLTRDFNKDCQYEKARQRYTARYHVGFSSRGYSVWRMFRVMMQTPYYRL
                     IERINIVRGSLSTFEHLTSEMAHTNLNDIAQEIKAPFYVLQGVHDMQTTYEDSKAFFEH
                     VGSAEKRFYAFQDTAHAPFVDEPEKMIEIMHEIVDRHVTS"
     aSDomain        29675..30481
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JC281_RS01365_Abhydrolase_1.1"
                     /evalue="8.70E-20"
                     /label="JC281_RS01365_Abhydrolase_1.1"
                     /locus_tag="JC281_RS01365"
                     /protein_end="304"
                     /protein_start="35"
                     /score="63.3"
                     /tool="antismash"
                     /translation="PILLVVHGGPGFPLYSFFRAHHIDLTDRYTVVFWDQRGTGMSYTR
                     ETVEMADLISDSYQLIQFLRHHFQQEQVYLMCHSFGTIIGTHLAHRYPEYIAAYIGMGQ
                     LGDVFHNEQCILQHLRFLAYEERNQRAIKRLSAIHLTRDFNKDCQYEKARQRYTARYHV
                     GFSSRGYSVWRMFRVMMQTPYYRLIERINIVRGSLSTFEHLTSEMAHTNLNDIAQEIKA
                     PFYVLQGVHDMQTTYEDSKAFFEHVGSAEKRFYAFQDTAHAPFVDEP"
     gene            30565..30711
                     /locus_tag="JC281_RS12385"
     CDS             30565..30711
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024803.4"
                     /locus_tag="JC281_RS12385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_233510328.1"
                     /transl_table=11
                     /translation="MLHYSTGELANMFGLTKRTIQYYDLQHILKPAYIDDNQYRMYTER
                     EVE"
     gene            30712..31293
                     /locus_tag="JC281_RS01370"
                     /old_locus_tag="JC281_01370"
     CDS             30712..31293
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020839.4"
                     /locus_tag="JC281_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01370"
                     /product="MerR family DNA-binding protein"
                     /protein_id="WP_242062915.1"
                     /transl_table=11
                     /translation="MRLILVMKSLGLTLKEIKQMLSVDGTLQTVRTLVTRKVEETEAEI
                     RQQQQQLKQMKQMQQMILDSSRAPVKNLSDIEDAMKQKPQHQRLVKHMFLMGTTATLFE
                     VIGIGLSWKYRQLWPAVLGFGSAITVAQKMTHTYYQQVSYMCPNCQQQFKPPYRTWLLA
                     PHTSQTRMLTCPNCGFKGYCTEIYDASMKL"
     gene            31469..33391
                     /locus_tag="JC281_RS01375"
                     /old_locus_tag="JC281_01375"
     CDS             31469..33391
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166501.1"
                     /locus_tag="JC281_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01375"
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="WP_014612920.1"
                     /transl_table=11
                     /translation="MKILAVTSCPNGIAHTYMAQEKLEQAAASLGIDIKVETQGGVGTE
                     NVLTAEEIAAAEGIIIAADRQVDLSRFNGKPLLKESVRAGIHQPEALIQRVVQGEAPVY
                     HSTGQAEASETSSHQSENNKNGMQMVYQHLMNGVSFMVPFIVVGGLLIALALSLGGEKT
                     ATQGLVIPDDSFWKPFEKIGALAFSFMVPILAGYIAVSIADKPGLVPGMIGGAIAADGS
                     FYGSTAGAGFLGGIVAGFLAGYIAKWIKNVKVPKAMAPIMPIIIIPIIASVLVGMIFIF
                     ILGAPIAAVFESLTTWLKGMQGANIVILALIIGAMIAFDMGGPVNKVAFLFGSALIAEG
                     NYSVMGMVAVAVCTPPIGLGLATFIQKRKFNRNEIEMGKASFTMGLFGITEGAIPFAAQ
                     DPLRIIPANMIGAMVASVIAALGHVGDRVAHGGPIVAVLGGIDGVLMFIVAVLVGSFVT
                     TALVLTFKKQPTATQAISRTSISTVKANDDTDVEDMLNPQAMIQTATPMDRDKAIDTII
                     NRLVRENYVANAAVLKEAVLAREAESTTALGMHIAMPHAKTNAIRQPIIGVLKHDQGVQ
                     WESLDGTLPQLVFLIAVPEQSHDTHLKVLQQLSKNLMHDDKRQRLLDTTNEAELYETLQ
                     RIIKA"
     misc_feature    33441..33455
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.59"
                     /tool="antismash"
     misc_feature    33442..33454
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     gene            33528..35387
                     /gene="spsA"
                     /locus_tag="JC281_RS01380"
                     /old_locus_tag="JC281_01380"
     CDS             33528..35387
                     /codon_start=1
                     /gene="spsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612921.1"
                     /locus_tag="JC281_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01380"
                     /product="LPXTG-anchored surface protein SpsA"
                     /protein_id="WP_096636639.1"
                     /transl_table=11
                     /translation="MTERKSPSSQNMRHRLVKAGTVLLLVGSGLQMPSTLSHEMTAIAQ
                     TDATDDLKTLRENADKKVKALQYLNTDYKNEFLALIREYDTSSKNIEVVVDEAEAANRL
                     AHDAQSDDEIQPELDAIDEKISALKAKVDEGQRESTEARQDVTSTETKSAESEGREPST
                     EGESKVKESSSAQTIVAPHHGQQDVSALKDHIKNDVDTLKQDYATQDKQVTPLQGIDSA
                     ITRIDHFVSESVDHKSDNYFEEKRQHLQNFEQDIKKRTDISGTEKATLLDDAKTVANQL
                     NAQNDTILTELQQHDDKRAAVESILGEIFNAQEAAQRAKQIDVKGKTDQQLANEIHQQA
                     DGLIKTSSDDLLLGMLENNSNTQGLVESILRTRFDKQEAHKIAGEIMQGKPSNAAILDR
                     LKDHFKANGKASGDDILNALINNTDADAEVIESILGGRLNAENAKLIADRVQKDKKKTH
                     QNLKAIEDELSAQANRLLTLRKQLQQIRHNTQTDMNDLFAPLRRIANILSGGLNRDDIH
                     SSGRTNDKLQQLLNRDHSLLGRGGDLFKHDFAPKPNIDPYQAINSQTASHGFLDGLFDQ
                     NGDFNLPNTGEIVKRTWLPLGILVVAIGVLILTVRFHKKTRKQ"
     gene            complement(35980..38055)
                     /locus_tag="JC281_RS01385"
                     /old_locus_tag="JC281_01385"
     CDS             complement(35980..38055)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729665.1"
                     /locus_tag="JC281_RS01385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01385"
                     /product="amidase domain-containing protein"
                     /protein_id="WP_070407771.1"
                     /transl_table=11
                     /translation="MNKKFIYTGLLSTALLIPSVTPQWAVAATPQTENGPKNPKVDNHD
                     QDVASDETRDDRKKQSQSSDKKETTKRESSKTSEKTTSQQHDSKKADLFDITSPLDSQL
                     KSSLSPHTDWFGQLFHSTLNETTDAPQHTYPAPTNDATSMPKQAQSSTPENRDFFEQLQ
                     AILSGGEDSKNDTTTSTDDALSSDQATTASPSTEQRDNDQENVTPSHNTDTSNEQPSTE
                     DATTSEKSKATSEGTSEVPPVNDDSTTEKPSTTVDAPDTEDKQTENHAPSTRDDATSDQ
                     QTKKNQNDAVIDALLDEYSEKAEQTHHAYQQQKEANEPSSTSKSQKHEAQVSDPDTFKS
                     SREQAPKQSYQNEADRKQTRQTTLFETMPDSDTSTNDAGTMRVVPQSSTREFINDIAKD
                     AHDIGQQEDLYASIMIAQAILESDSGRSELSRDPYFNLFGIKGSYHGESAHFKTLESDG
                     KQLYEIDAAFRKYPDHKASLQDYADLIKGGIDGNPNIYEDVWKSHSSSYHDAASALVGT
                     YATDPQYDQKLEALIEAYDLTRFDQDDMPDLLAEKDDNETAKSDGGAFKPFAISADSPY
                     PYGQCTWYVYNRMAQFDIHISGTMGNAADWTYSALTQGYSVSSKPKVHSAVVFNPNELG
                     ADRYYGHVAFVEKVNRDGSIVISESNVKGLGVISFRTIDAKDAAQLDYISGDLATE"
     gene            38384..41218
                     /locus_tag="JC281_RS01390"
                     /old_locus_tag="JC281_01390"
     CDS             38384..41218
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167306.1"
                     /locus_tag="JC281_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JC281_01390"
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="WP_198456146.1"
                     /transl_table=11
                     /translation="MKNAIKLFLTDIKKIAKTPGAMVLILGLAILPSFYAWFNLEATWD
                     PYSNTDGIKIAVVNEDKGDTVRNKKINVGNQIEETLRKDDHFDWQMVSREKADRELKMG
                     KYYAAIYIPEKFTHQVTGIVRKDPQQAEVEYKVNQKLNAIAPKMTDAGSSEIVRNANKK
                     FNETVTKALLDEANRIGIKLEDQLPNYHKVRDGIYAADNALPKIEKFRKTLIYLDENQD
                     QIDQYADKFRALDQYKDDAVTATERLNQLNASIPAINERAKLIVSLNQAMPDIERVLQV
                     ASGVPNHFPEINDGVDRAIAGTDQALVKLNEIQQLLPAVEQRVNVLQNGVDRGRVVNQA
                     VGENARNATTTTPQSTRGTAYHTAAMSTTTQGDSTNVPAGHIISPADAQTMTTAYGDTL
                     QQVNQAVTQQLKATSADLDTAENLSYGILSAKDPKQFESPLNHLIARMNNATKTIRDYR
                     DYLANIEKSEGVDLSDAQSRLKTVQEDIEQRTKRLNALKDAISAGNSGQAEAADVLDSL
                     SKAKDQLNAVGKYLRGDFTQTLRDISDRLGAALNQGATTLDNVQQRLNQLNSAIRQGQQ
                     FLTEGQQRLHQLSDTLPRVEAAYINAMKAAQAYFPQFRQKVAEASNFVENDLPRVEGRV
                     SDATATVNEKLPEAFAQYDRLRNILDTNQPKAKETLHRLAEFARNDLPQVEEDLQKADG
                     IFKQLDKENTIEDLIDLLRNDLKKQAGVIASPVDLQKENVFPVKDYGSASTPFYTALAI
                     WVGALLLVSLLSVHNKHPELKPYLTIRETYLGKMGLFLLMNIIQATIVSIGDIVILKAS
                     IESVPLFIAISMYSALIFTTIVYTLVSVLGNPGKALAIVLLVLQIAGGGGTFPIEVTPQ
                     FFQSIHPFLPFSYSIDALREAVGGPVPQILTYKLTMLTVFGVGFFLVGLIGKPYLDPLA
                     QGLAEKAEKSDVLE"
     misc_feature    complement(41435..41451)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.99"
                     /tool="antismash"
     misc_feature    41620..41636
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.98"
                     /tool="antismash"
ORIGIN
        1 tattgacgcg ttcagcaatc ccattcaaat gtttaaggtc aaagccttgt ttcatcccat
       61 caaaatccat gcttgtgacg agaagctcac cagccccgag tgattcgact tcttggaccc
      121 aatcatacac ccgtttatca gtgcgctttt taccgccgtg tgtacaacag aaataatcat
      181 ctaactttgg attatattga ctgtcgatgg cgatacaaat gcattgtcgt ccaaactttt
      241 cgctcgcttg acggatgagt tcagggttat tgagtgctgc tgaattaagt gatactttgt
      301 cggcaccatg ctttaacaaa tcagaaatgt catcgagtga agcaataccg cccccgaccg
      361 ttaatgggat aaacagttgc tcggcagttt gttggataat gtctaacgtt aaagcatggc
      421 cccgctcagt tttggaaata tctaaaaaga cgagttcatc ggcaccggct tcgttatagt
      481 acatggctag atcaacgggg tcaccgatgt cccttaaacc tttaaattga atgcctttta
      541 cgacgcggcc atctttcaca tcgaggcaag gaatgattcg ttttttaatc aacttaatcc
      601 ctcccaaaat gtgctttgat ttgcagcttt accgacaatt gcagcagtaa cacctgaagc
      661 ttcaagtctt tcaagatctt gtcgatcacg aatgcctcct gatgcgacga caggtaacga
      721 tgtcgcttgt gcaagttgag cggtgatttc aaagttcgga cctgctaatt taccatcttt
      781 cgaaatatct gtgtaaataa cgccacctaa cgggaatgtc tcgatttgag cgacgtagtc
      841 aaataagtct aacgcagcat cttctgtcca accgttaatt ttgattgctg tgcgatatgc
      901 atcgacggat acataaattt tcccaggaaa taactgactc atttcagcga gccatgctgt
      961 attcgtaatt gcttgtgtgc cgacaataca gtaatcgaca cctgaatcaa aatagcgtcg
     1021 caacgtagcc tcatcacgaa tgccaccccc gacttcaatt ggtttatcac tcgcttgaat
     1081 gagttgttga atgtaatcca tttcaatcgc gcgttgtgct ttggcgccga tgaggtcgat
     1141 aatgtgaatg cggtcgacac tttcgaattg attgtaaaat tgaatactgt cttctgcgct
     1201 tctcgtcatc gcctctgaag tgctgtaatc tccctcggtc aagcgcacac ttttaccttc
     1261 aattaaatca atggcaggcc aaattttaat catgttgcca tcctcctttt aatgcttgtg
     1321 ctaagatgtc caagccataa ttcccacttt tttcagggtg aaattgaatg ccgatatatg
     1381 gaccgcgttg gacgatacca ggaatttgag tgccgtaatc tgtgtaggcg acaacatcgt
     1441 cattcatcgg cgcttggtac gtatgcacat aatagacgtc tttatctaaa ctcgggacgt
     1501 cgctttttaa ctgattccaa ccgagatgcg gcactgtgta aggcgtgtct atcgcacgaa
     1561 catgaccttc gaaaaagccg agcccaggga catgaccttc atcgctaaaa gcatagagca
     1621 attgcatccc gagacagata ccaataatgg gcttttgttg tcgtttcaat aatggcgcca
     1681 gttcataacg gtcaatggct tgcatggcgt ctttaaaatg accgacccct ggtaaaatga
     1741 gctgttcggc acgttcaatg actgcaggat cacgtgagac gacgacatca tagccgagat
     1801 gttgtacggc acgttggaca tttaaaatat tgcctaaacc gtaatctaca atgacaatca
     1861 tgattcaatc acacctttag acgaagggat acgtgcttct tgtgatgggc gcaatgcttg
     1921 ttttaaggcg cgggcgaacg ctttgaatac tgattcaatc tcatggtgtg tattgccttg
     1981 gtgcagtaaa tcgatgtgta ccgtgagtcg cgcattgatg actaacgctc taaaaaattc
     2041 ttcaactaac tctgtatcaa actgcccgac cttttcttta ctgaatgacg cattaaagtt
     2101 taaataagga cgtccactaa tatcgacaac agcacgggtt aatgtttcat ccattggtaa
     2161 atattgttgg ccgtaacgct cgaaatgttt tttatcgcgc gtcagttgta acaataattg
     2221 accgagtacg ataccgatat cttcagttgt atggtgatca tccacccacg tatcgccatc
     2281 gacatgaata ttgaagtaca ggccactgtg aaagctgagt agtgtcaaca tatgatctaa
     2341 aaagccgaca cctgtatcga tatgacttgt ttcttgcact tctgaaagtt caatggcaat
     2401 tttagtttct ttcgtttcac ggttaatttg atatgtcatg acgttcactc cattctttga
     2461 cgacttgttc aaaacggtct agctgggctt ctgtcgcaat ggaatagcgg acaaatcctg
     2521 ccatcgttgc ttcagatggg tcattgtaaa aacgtgggag aaagccgtgt tgttccacat
     2581 ggcgtccgag taccattgct tgaggtccag cagttagcac aaagttggtc tcactcggat
     2641 aaatcgtcat atgtggactg gcatattgtt gtaatatagc tttcaaccgt gagcttaaat
     2701 gacgttggtg tgcaatgaat gcttcagtgt ctgcttggtt ttcgaatagt tgaataccga
     2761 ttgccattgt gagcgcactg agcgggtaag ggtgttcaat ttgtcgaaca agttgaatcg
     2821 ttttttctgt gccaattaac acaccgagac gcaacccagc catcgcataa gctttcgaca
     2881 atgtgcgcat gaccaaaatg tgatcttcta acgcaatatc gagcggtgtt gaaaaatcaa
     2941 tatatgcttc atcaatgacg agatagcctc cgagttgttt catgcgattg gcaacggcca
     3001 gcaaataact ttcatcaaaa cggtgaccag tcggattgtg tggattactt aatatgaaga
     3061 aactcggctg taccgcttca atcttgtcca atacggcttc aactggaaaa gataactctg
     3121 atgtagcatc cacaaattga atatcgcggt tcacttggcg cgcgtaatct tgatacatga
     3181 aaaagtcggg gttgagcgtt aaacatggtc catctggcat gatgagcatt aacttttgaa
     3241 tcagttcatc agagccattg ccacaagtga tttgttcgcg tgtgaaagta ctaccgtagt
     3301 attgcgcata agctttacga aaacgatcat acgccacgtc aggatagagg tgatagtcac
     3361 acttttcgat gagttcggtt aatgtttctg tcgatagtgg tttgatcgga ctttcatttt
     3421 tgttcatacg aatcatgcgt tgtcacctct ttgtctaatt tctaatgatt tttggtggtg
     3481 atacagttgt tcatcttgag cgatacgtgc ggcatctcga tacgtttttt cataggttgc
     3541 ttctgataag tgaatcaccg tatgttttgt taaaaagtca ttgaccgata aaccgtgttg
     3601 aaagcgggct gtccgttgtg taggtagaac gtggcttggt cccgcaatat agtctccaat
     3661 cgcttccggc gcatagccac ctaagaatag gctgccaaca tagtgaatat gtggcaaata
     3721 gttttcaggc tgcgcggttt gaattgatgc atgctctggt gcaatagtat tcatcacgtg
     3781 acaactgtct tcaaaatcag tcgcgtgaat gagatagtga ttatctttca aactgacttt
     3841 taaaatgtca tgacgtggtg caccgttaag tgtttgttgg atacggcttt ctaaactttc
     3901 gagcaatgcc aaatctgttg aaatgacaaa tgtccgcgcc atttcatcat gttctgcttg
     3961 agcaaataca tcatagacaa ctgcttctaa gttacatgta tcatcaatta tcaatgcaat
     4021 ttcactgggt cccgcaattt gatcgatacc gacttcgcca tacaatgctt ttttcgcata
     4081 ggcgacatat tgattacctg gaccgacaat tttatcgact ttcgggatgg tttctgtacc
     4141 ataagcgagt gctgcaatac tttgtgcacc gccgacttga tacacatgat ccacaccagc
     4201 aatatgacat gctgcgagta cactcggtgc aacaccattc tgctgaggcg gcgtgacgac
     4261 actgatgttt ttcacaccgg ctactttcgc gagtgtggcc gtcattaata cagtggaagg
     4321 gtagctcgct ttaccgcctg gcacatatat accgacacgt tcaatcgggt gatacacttc
     4381 ataaagttca ggtgtcgcgt attggttttc gtatttgatt tgtgtttgat aatcgcgaat
     4441 tcttcggaaa ctatgctcaa gtgcgtgacg taaatcttca tctatattgt ggtacgctgc
     4501 tgcaatgtca gcttgtggca cttccaacgc ctccaccttg atgccatcaa attgttgatt
     4561 atagtcatgt aatgctaggt ctccttcacg tcgcacgcgt tcacaaatgg cagtgacttg
     4621 tgcgtgaatt tcaggattga atgtttctgt tgtttcgaat tgttgtaaaa aggtttggct
     4681 attaacgatc aatgagcgac actcctaaca tgttaataaa tgcatcaatt tctgatgatt
     4741 gggtgaaaaa gctttgtcga ttcgtaatga gttgcgcttg aatatctgta atatgttctt
     4801 tttcgactaa cccgttcgaa cgcaatgtcg tccctgtttg aacaatgtca acgatgccgt
     4861 cgaccatgcc aatcacacaa gcaagttcga tagagccgga taattcgatc agttcgacat
     4921 cacgtcctgt cgctttaaaa taatctcttg ctgttttagg aaaagaagtt gcgactttgt
     4981 gatagtccgt tgtctcgtca aatgctgcga ctgaaaagtg acattggcca aaaggaagtg
     5041 caagcagttg attgacgtcg tattgagctt cattgagaat atcactgcct gtaatgccaa
     5101 tatcagcaat gccttgttcg acatagatag ggacgtcatt gcctttgacg aataaaaaat
     5161 ggaaaggcga tactttaatt tgaagctggc gttctctaga ctttaattgt gctgccaaat
     5221 cgttttgacc ttgtgattct aaataggcga taaaactttt gagcaggcga cctttagcta
     5281 atgcgatcgt aagcacagtg attcctcctc gttataatgt taaccctaaa ccaaaaccct
     5341 ctagcggccc gttataatag cctcctgata gcgttcgacc actgttttga aggtgtgcat
     5401 gaataaacgt ctccttatag tatgaacgtg gagcttgcgg tgtaatatcc agatgaatcg
     5461 tgtcgatgtg aagcgatttg aagtatgttt gccaacgatt caaactgcga ataatgacgt
     5521 gatcatgtgg atataacgca tttaaaagtt ccagttgctg atgtgtcggt gtgagtaata
     5581 accgtacgag cggatgactc atgccaagag cggatttgag tgccgaaata ttacgctgtt
     5641 caacccatgt cagtagctgt tcacgttcag cttgatgctc aagcaataaa tcgatgagct
     5701 ggtaatgccc aatcacgaca tattgaattt catcttgtaa gtgttgcgag ataaattgtt
     5761 gaaacgtctc aaaagcatgg tacatttctt gaatatgtgg gcgataacat tccagaccaa
     5821 gttgtgtttg gacttgatgg tgtcgcacaa tcggccccgt ataagccaca gcggaatgat
     5881 tgagttgata atgttgataa tagcgcacaa gttgatcggt gaaatcattg cgtaaagcaa
     5941 acaaagtatc atctgcctgc cacacactgc gctctttcat ttgttttaaa tcatctggag
     6001 acagttcatc ccacacgagt gtttcgataa aagcagtctc aattggttcg aaatcattgg
     6061 ctgttgctaa ctttaaaaag tcaatttcat attgtttatt ttgtatgaaa ggttgtccca
     6121 ttatccaccc tcgctttcgt tctctaccaa gttaaagtat ttgaatagaa tatgacaatg
     6181 gtagcacaga gattttcaga tttcaacaca tttttctgaa tattttattt ttagtttcgg
     6241 ctacttgccg tcatcatcat cagactgtct caaaattatt cgatttgtac acggcaatat
     6301 gccatgccat aatggttcaa gcacgagcat gcgttgcaca tattcattac caatttatcg
     6361 caatcgactc aaaataaaaa aatcgtattt tgaagcatct aattgtataa ttgagagggt
     6421 caagaaatta tatcaataag gagcgttccg tatgaatttc gaaaaatata ttgatcacac
     6481 gttgttaaaa ccagaatcaa cacgtgcaca aattgacaaa attattgagg aagcaaaagc
     6541 atatcatttc aaatcgattt gtattaatcc aacacacatc gcttatgctg cagaaaaatt
     6601 agcagattca gatgtgctcg tatgtacagt gatcggtttc ccattaggag cgaacacgac
     6661 ggaaacaaaa gtatttgaaa cagaagatgc gatccgtaaa ggcgcagatg agattgacat
     6721 ggtgatcaac attggtgcat taaaagacca acgttatgat gacgtgcaaa aagatattga
     6781 agcggtcgtt aaagctgcag aaggtaaaac agttaaggtc attatcgaaa cagcactttt
     6841 aactgaagaa gaaaaagtaa aagcatctga actaactaaa gcagcaggtg cccatttcgt
     6901 gaaaacatca acaggtttct ctacgggtgg cgctacacct gaagacgtga agttaatgaa
     6961 agatacagtc ggcgaatcag tagaagtgaa agcagctggt ggcgtacgta acttagaaga
     7021 cttcaaagca atgattgatg caggtgcaac acgtatcggt gcaagtgccg gcgtacaaat
     7081 tatgcaaggt ttagaagtag attcagatta ttaatcaaag aattcaataa atgtgggagt
     7141 gattaagatg acagtacctt ttcaacgcgt tcatttaatt gtgatggatt cagttgggat
     7201 tggagagggc ccagacgcta aagactttaa cgatgaaggc tcacacactt taaaacatac
     7261 gcttgaagga tttgatcaaa agttaccgaa ccttgaaaaa ttaggcttag ggaatattgc
     7321 gccattacca gtgattgacg ctgttgatca tcctttagcg tattatacaa aattaagtga
     7381 agcgtcagtc ggtaaagaca cgatgacagg ccactgggaa attatgggct tgaacattat
     7441 gcaaccgttc aaagtgtatc cagaaggttt tccagaagag ttagttcaag aaatcgaaca
     7501 actttcaggc cgtaaagttg tcgcaaaccg cccagcatcg gggacacaaa ttattgacga
     7561 gtggggcgaa catcaaatga agacaggaga cttaatcgtc tatacttctg ctgaccctgt
     7621 gcttcaaatt gctgcacacg aagatgtcat tccgttagaa gagttgtatg acatttgtga
     7681 aaaagtccgt gaactgacaa aagatccgaa atatttaatt ggacgtatca ttgcgcgtcc
     7741 atatgttggc gaacccggta acttcacacg tacaagtaac cgtcatgatt atgccttgaa
     7801 gccatttggt aaaacagtga tgaatacgtt aaaagaaaat gactatgatg tcattgcgat
     7861 tggtaaaatt aacgatattt atgatggtga aggtgtaact gaagccgtac gtacgaaaag
     7921 taatatggat ggcatggatc aactcatgaa tatcgtcaac aaagacttta aaggattaag
     7981 ctttttaaac ttagttgact ttgatgcatt atatggccac cgtcgtgata agccaggcta
     8041 tgcacaagcg attaaagaat ttgataatcg cttaccagaa ttgatggatg cattgcatga
     8101 agacgattta ttgattatta cagcggacca cgggaatgac ccaacagcac cggggacaga
     8161 tcatacacgt gagtacattc cagtcatcat gtatagtccg aagtttaaag gcggacaagc
     8221 attagaaggc gatacaacat ttagttcaat cggtgcaaca attgccgata actttggcgt
     8281 aacattgcct gagtttggac gtagctattt aaatgaattg aaataattga gagaagtggc
     8341 tgatacctgt aaataggtgt cggctgcttt tttattttga atgttaagtg ttaaatggac
     8401 gtgaactacc ggcttgaact ttatttatac aaagtcactt attatattat caatcgttta
     8461 tatttttgtt aatatggtag gaatcaatgt tttaaaagga atatctttaa cggcagtaag
     8521 gattgaagga agttgacatc cccattgtaa acacatcaac tggaaggcat cacagtacaa
     8581 aacatgtaga aacccctgct taatcatctt ttataaaaaa cactcacaca tacagcaccg
     8641 ttattatctg acaaaagtta gatcgtggcg taattttcta tattaaatca ttgtaactgt
     8701 aaaaaattag tcattctatc tatcgggcat gtttgttgtg ttgtgataaa ctagaataaa
     8761 gtttcaaaaa gtctcatcat tgcaaaagga gccaaaatcg atgtttaatt taacgatatt
     8821 actgttggag cgtgtcggac tcattattat attggcgtac attttaatga attcaaaata
     8881 cttcaagcat acgatgcaac agcgacaagc atgggcatca aagtggcaat tgtgtatcgt
     8941 ctttagcctc tttgcgctgt tgtctaactt tacgggtatc gtcattaaaa atggcgatat
     9001 tttagcgggg agcatttatt ttcaattaga tgataatgtt tctttagcga atacacgtgt
     9061 gctgacaatc ggtgtcgcag gactggtagg aggacctttt gtcagtgtgt ttgtcggcat
     9121 tttatctggt atttttcgcc tttatatggg tggtgcagaa gcatatacat atttaatttc
     9181 ttccctattt attggactta tttctggata ttatggacgt caagcgctcg aacaacacca
     9241 atatccaacg attgcgaaaa gtgcattgat cggtggtatg atggaaattg tccagatgat
     9301 ttgtattttt tcgttcgccc aagacaaaca gtatgcgatg gacttgattg ctttgattgg
     9361 actgccgatg attgtcgtta atagtgcagg tacagcgatt tttatgtcta tcatcagttc
     9421 aactttgaag caagaagaac aaatgcgtgc cgttcaaaca catgatgtat tagaattgac
     9481 caatcaaacg ttgccttatt ttaaagaggg gctcaatgaa gactccgcaa aacacgtggc
     9541 gatgattatt aaagatttga tgaaagtatc ggccgtcgct attacgaatc gacatgacat
     9601 tttggcacat gtgggggcgg ggagtgacca tcacattcct aaaaaagaga ttattacgca
     9661 tttatctaaa gcggtactac aaactggtga gcttaaagaa gtgcatacga aagaggaaat
     9721 tggttgcacg catccgcatt gtccactgca tgccgcgcta gtgattccac ttaaaatgca
     9781 tgggaaagtg acagggacgt taaaaatgta ctttacgaat ccgaccaatt taacgtttgt
     9841 cgaacgacag ttagcagaag gtttggcgga gatttttagt agtcaaatcg aactgggaga
     9901 agcagagatg caaagtaagt tgttgaaaga tgcggagatt aaatcccttc aagcacaagt
     9961 gaacccgcat ttctttttta acgcgatgaa tacgatttca gcattagtac gtattgatag
    10021 tgaaaaagcg agagaattat tactcgagtt gagccatttc tttcgttcaa atttacaagg
    10081 ttcgcgtcaa aacacaatca ctttagagaa agagttaagt caagtgacgg cttatttatc
    10141 actcgaacaa gcgcgttttc caggacgatt cgatgtgact tttgatgtac cacaaaaggt
    10201 gcaacaagca tctgtgccac catttttaat tcaaatctta gtggaaaatg cggtcaaaca
    10261 tgcgtttcca aaccgtaaaa agggcaacac aattaaagtc ggggcacgat taaaagatgc
    10321 gcaacaactc tatattgaag tgagtgacaa tggacgtggg attccaccag ataaattgac
    10381 gcaattgggc caaaaagtgg tcgagtcaga gtcaggaacg ggtagtgctt tagaaaattt
    10441 aaatttaaga ttaaaaggtt tgttcagtga gcaagccgcg ctacattttg atagtgatga
    10501 cacagggacg tgcgtatggt gtacgttacc ttatcaacag aaggaggatt aagtcatgcg
    10561 tgcattaatt gttgatgatg aaccactcgc gcgtaatgaa ttgatatatt tattgaatcg
    10621 tatcggagga tttgatgttt tagatgaagc ggaaaatgtg agcgaaacga ttgaagcgtt
    10681 attagtaaac gaatatgatt tggtgttttt agatattaat ttaatgaatg aaaatgggat
    10741 tgaattaggt aaaaaaatac agaagatgaa agcaccgcct gcgattgtat ttgcgacagc
    10801 gcatgaccaa tttgcggtac aggcgtttga actgaatgcg acagattata ttatgaagcc
    10861 attcgatcaa tctcgcattg cgcaagctgt ggcaaaagtg cgtgcacagc aggaaaagta
    10921 cgaagacatg cacgtgccac attcagctgt gaaagtaacg caacctttac cgattgaaat
    10981 tggtgagcgt attcatatgc tgaaccctgt tgacgtgatt ggtatttcgg tcaatcaagg
    11041 tgtgaccacg atttatacga cgcaaggtga gtatgagaca catgagccat tgagtgcgta
    11101 tgagaagcga ttggatgagg cacagtttat tcggattcat cggtcgaatg tgatcaatcg
    11161 acagcatatt gaggcgattg agcattggtt taattcgacg tacatggtga cgttgacgga
    11221 tggggtgaag atgcaggtga gtcggtcgta tatgaagaag tttaagcagg cgatgggttt
    11281 aaagctgtga gtggaatgat gaggagtgag acagtcggtt tgatgtgtct cactctttga
    11341 tttcatgagt ggtattttag aaatacttga agatacattt gtggttttgg ggtaatcgtt
    11401 gactgctgaa tcgtgctgcg ctttccaagg ggctgcccct ccaactaaat tcggcttgat
    11461 tgagatgtac gcaggatgga agccaaattg gattttggga gcggtacaga aatctcatgt
    11521 gtaacaaaga tttcgtcgta ctgcccccgc aaggctgact agacttctca aaagcgagcg
    11581 cattgagaag tcagacagct actgcgataa acaggaacca ctattaaaga gtagaaatca
    11641 tatttagata tttattttat ccctcgggag tcttgcacga ttcttgcagt ctgggtaagt
    11701 gcctcaagct ggtcaatggt gggttgaaat gattagaacg aaactgcacc tcatgaaaca
    11761 aagcctaccc cccttcagta ttcgaggaga gaaaggatag tgcgagatct tgaatcgtgt
    11821 tgcgctttcc gaggcgatga caccggtcaa ctatttaccg cctcatatat agtgttcagt
    11881 gaaagggaac aggttcgaat tgctgaaagt tgagtgagtt taaaaaagta tgctttgcgc
    11941 cactatatga catttaaata gtgtggttgt tggacaaggg tgtgattttg tatttcacgc
    12001 ctcttttttt gcatttcgcg atgaaaacgg tatatgtgaa ttttttcata atataatgaa
    12061 gtcaatcaga gacgcacggg aggttgtaaa agtgaaacaa aaagaagaga aaacgtatag
    12121 ttttttacat caagtgttag tgattgcatc agtgttgttt gtttcaagta ttattgaatc
    12181 atttatgccg attcctatgc cggcatcagt gatagggctc gtattattgt tcgttttatt
    12241 atgtacaggt gtgatcaagc tcggtcaagt tgaaaaagta ggcacagcgt taacgaataa
    12301 tattggcttt ttattcgtgc ctgctgggat ttcagttgta aattcattag acattattag
    12361 tgcaagtccg attctcatta ttggcttgat tattatttca acaattctac tacttgtatt
    12421 tacaggcttt gcgtcacaaa ttttaatgcg tatgacgacg aaagataaag tagcaacacc
    12481 gccgcgtacg aaagcgaaag tgaaaggagc gcattcacat ggttaatcat ctcgctatag
    12541 acacaccgta tttcggtatt ttattatcag tgattccatt tttaatcgca actgtacttt
    12601 ttaagaaaac aaatggcttt ttcttattcg caccactctt tgttgcgatg gttttcggag
    12661 tagcgttctt acactttaca ggtattccat atgaaaagta taaaattggt ggggatatca
    12721 ttaatttctt cctcggacca gcgacaattt catttgcgat tcctttatac aaaaagcgtg
    12781 atgtcttggt gaaacattgg caccgtatta tcggcggtat tgggattggt actgtattgg
    12841 cacttgttgg tattttcttt gtcgcaaaag cacttcaatt cggtagtgac attatcgcat
    12901 ccatgcttcc gcaagcagca acaacagcga ttgcactacc tgtatcagaa ggcattggcg
    12961 gtattaaaga gttgacatca ttagcggtta ttttaaatgc ggtcattatt tatgcgttag
    13021 gtaataaatt attgaaatgg ttccacattg atgatccgat tgcgagaggc ttatctttag
    13081 gaacgagcgg acatacgtta ggtgtagcgg cagcaaaaga attaggacca gtagaggagt
    13141 caatggcgag catcgcgatt gtactggttg gggttgtcgt tgtagcagtt gttccgattt
    13201 tgacacttat cttcttctag acacaattca atagcataaa aaatgttgta cagtacgtgt
    13261 aagttggaat gcgcgtctgt acaacttttt tgtatacaga attgtcaaat atatcacaat
    13321 agtttttgcg tgaacgtttt cattgtaaaa cttataatag aagaaaatag gatagaaggt
    13381 gagcaaatga aaaagttaat ccaggataag acgcactttt tgcaagacat gctagacggg
    13441 ttgaaaatta caaatccgaa cattgatgtc attgcagata cggtcgttgt acgtcagcat
    13501 aaaaaaacgt ctggtgtcgc attagtttct ggtggcggca gtggtcacga acctgcacat
    13561 gcaggctatg taggtgaagg tatgttagat gctgcggtat gtggtgaagt gtttacctcg
    13621 ccgacaccgg ataaagtgtt agaagctatt aaagcggtgg acaatggaga cggtgtgtta
    13681 cttattgtta aaaattacgc aggtgacgtc atgaactttg aaatggctaa agatatggca
    13741 gcgatggaag acattcaagt cgaaatggtc gtcgtaggtg atgacattgc gattgatgat
    13801 gttgaaaaac gtcgcggtgt tgcgggaacg gtctttgttc ataaatatgc cggttattta
    13861 tcagaacgtg gtaagaaatt aacagagctg aaaactgaag tcgaagcatt gattgatcaa
    13921 attcgtacga ttgggatggc attaacaccg cctgctgtac caacgacagg taagtatggt
    13981 ttcgatattg aagagagtga aatggaaatc ggcattggta ttcacggtga acgtgggtta
    14041 gaacgtgtac cagttgaacc ggtagaacaa attgtgcaac gtttgattga acaattgaaa
    14101 gccgaagtgg caagcgatga attgattgtc atggtcaatg gcatgggcgg tacaccatta
    14161 tcagaattag atattgtgac gaaatatgtc gcattacagt tagaacaaga aggaaagact
    14221 gtaaaaggat ggtttgtagg tgattatatg acatcactcg atatgcaagg cttttcatta
    14281 acatttgttc cttatgatga acacatatta tcagcatttc gcgcacctac aacaagtcga
    14341 tttttttaac ataatccagg aggtttccaa gatggacgta gcaactttaa aagaacgatt
    14401 acttgcatta aaagaaacat ttgaaacaga agaagaggct ttgacagagt tagaccgtgc
    14461 gattggtgac ggggaccacg gcgtgaatat gcgacgtggt tttgaagcgc ttcctgacca
    14521 attagacgac agctcgatgc aagctttatt caaaacgaca ggtatgacgc tcatgtcaaa
    14581 agtgggcggc gcgtctggac cattatacgg ttttagtttt gttaaaatgg cgcaagttgc
    14641 aaatgatgag attgatcatg acaacttagt cgaattgtta aaagcatttg aagaagctgt
    14701 agcccaacgc ggtaaagtaa ctttaaatga aaaaacaatg tatgacgtca ttgcacgtgc
    14761 gagagaagcg gtagaacaag gtgagactgt cgatttagcg acgttacaat catatgcgga
    14821 tgcgacacgt gatatcgaag cgacgaaagg ccgtgcttca tattttaaaa aagactcaat
    14881 cgggtatatt gaccctggtg cacaaagtag tgtttacatt ttaaatgcac tgataggagc
    14941 tgatgaagcg tgacacaaat cgttttagtg agtcacagtg ataaaattgc agaaggtaca
    15001 caagaactcc ttgcacaaat ggcacaagat gtgaatgtcg ttgcgattgg tgggatcgaa
    15061 ggtgaaattg gtacgtcttt tgatgacatt tccgcagtgt taaatgatat aaacgatgat
    15121 gcgatttgct tttttgatat tggttcatca gaaatgaatt tggatatggc gattgaaatg
    15181 tatacgggga cacatcgtat tgaaaaagtg gatgccccaa ttgtagaagg cagtttcatt
    15241 gcggcagttg ccttatcgac aggtcaaacg atagatgaag ccattgcatc tgtcgacgaa
    15301 gcattttaat aacatctata gaaataggac agcttgagcg cgtaacgcac gacaatgttg
    15361 tcctattttt taacgttatt taattttttt cacaacttca gattttaaac caatttgtcc
    15421 aaaaccagga attttacagt cgatatcgtg gccgtcttca gggtcaacga gtttaatatt
    15481 ttttactttc gttccttgtt taatcatttg agaactgcct ttgattttta agtcgcgaat
    15541 gactgacacc gtgtcaccat cttgaagtgg attaccattt gcatcacgga tgacggcttg
    15601 ttcagcagct gcttcgagtg tatcgtttgt ccattcatac gcacacatcg ggcaaatgta
    15661 aagtccgcca tcttcgtaag tatattcaga atcacactgc ggacagtttg ggattgcggt
    15721 tgtcatgtta gaatcaacta ctttcattaa aaatataaat ctaatctaac acattctgag
    15781 tgaaaagtat gtaacaaatt taacgacatg ttacgataat tgtatgagac gcaatgacgt
    15841 gtcatacggt cactaactaa aagaaagagg gatggaagat gacaaagttt gatgtagaaa
    15901 acccttcaac aggagaagtt attaaaactt atgcatttac agaagaagct gaaattcatc
    15961 ataaaattga acgtgcgtat gaagcatatt tatcatggcg tgaagtcgat gcgcatgaac
    16021 gttcacgttt attatggcaa tggtcaactt taattaaaga gaaccgtgaa gcattagcag
    16081 aactgattac acttgaaggg ggcaagcctt atcaagaagc attaggtgaa gtggattacg
    16141 ctgttggtta tgtggattgg tatgctgaag aagtgaagcg catttacggt cgaacgattc
    16201 cggctaactc gccagataag aaaattttag tggataaatt tccggttggg gttgtagggg
    16261 ccattacacc gtggaacttc ccagctgcaa tgattacacg taaaatggca cccgcgctcg
    16321 ctgcaggttg tacaatcgta tgtaaaccag cgacacaaac gcccatgacg acgattcgtt
    16381 tagtcgaatt agcacatgaa gcgggcattc ctgaagatgc gatttcatac attttagcaa
    16441 gtggtaaaac agcagggaaa attttcactg aacatgaact gatcaacaaa gtgacattca
    16501 caggctctac acccgtcggt aaaaagttaa tcgaacaatc agcagcatct gtaaaaaatg
    16561 tcacaatgga actcggcggt ctggcaccac tcatcgtgca taaagatgcc gacattgaac
    16621 atgcagtcga acaaacgatt aaaacaaaat ttagaaatgc aggccaaact tgtatttgtg
    16681 ccaaccgtat ttatgtacac gaagacattg cagaagaata cgaaaaacaa ctcattgaac
    16741 aagtccatgc cttaaaagta ggggacggta tggagaaaga tgtgaaaatt ggaccactca
    16801 ttaaccaaaa aggcgtcgat aaagtgctcg atcacattca agatgcggtt gaacatggcg
    16861 gtcaattatc acgtgaatta gatgacattc aagcgctagg tggtaacttc ttaaaaccag
    16921 tagtcattac gaatgttaac catgatatga aatgtatgca cgaagaaaca ttcggtccag
    16981 tagcgcctgt aatgcgtttt gctgatattg atgaagcgat tcatttagcg aatgatacag
    17041 aatttggatt ggcatcttac ttcttcacaa acgattatcg tacaggactt tatatataca
    17101 acaacttaca ttacggtgtc gtgggttgga atgacggtgc accatccgca ccgcatgcgc
    17161 catttggtgg tgtgaaagag agtggttacg gccgtgaagg tggtattgaa ggcatcgaac
    17221 cttatctaga gactaaatac ctctcaatcg gtacaaaaac taactaacga ttgattgaat
    17281 caactaaagg ctgggagaac atatcttccg gtcttttttt ggtgaagtta gatagatact
    17341 gcgttaaaca gtaggtgttt ttaagtatca aaagtcgcat ttagtccttt gatttacccc
    17401 tcaagtgtct cagtcttttt ggatatctga cttaaaaatt actgaagcaa tgggcaagtt
    17461 tttaaaaaag aacatcaaaa ttatgcatct gattcatcga gtagattttg ttttaattta
    17521 tgaacactta gcttttcttt gcccattcat tcaccggcta cgaacattat tgtgtatttt
    17581 attacgtgaa ggcggcgggc taaacacact aagtcatcat ctatactgta tgtttcttta
    17641 tttctttcct ctttttcaag gtgcatgata ggcatttttt taaccgctag aaagtaaaag
    17701 acaagggcat gtgagacacc cttggaaaaa ttaaattaat aagcgtattt tttcatataa
    17761 ttcacgaata taaggtattg caataaattt tgtttagatt tattgaagtt tttaaaatta
    17821 gattcaacag aaatttcatg agtcatatca ttatatttaa tgtcatatgc tgaaagatgt
    17881 tcatcaaaaa tctttttatg ttttttcgat tttttataaa gaccccatta ttttctaata
    17941 cgaatatagt atagccattg tctgttaaag tgatgatgtc tcgagcttaa tcgtatatag
    18001 catatataat aaaattatct aaagtgtaat ctttaaaagg acagcctatt tttactacat
    18061 tgtttgacaa attagaaaac gctaattctt ggttgtacca atcatgatat tcttttttaa
    18121 tttgttagca tcaaatgtag ccatattaac cctcctccat tcaaattctt gtaaattatt
    18181 atagtctaaa aacaatatat aagcactatg catgttataa atatctggaa aatctttcac
    18241 gaatatttta taagtgaact tatatttttt atataaatta atgtaaatat gaatatgact
    18301 cgttggagca actgtctcat tagaattcta atggatgaga ccattaacgt ttattttgac
    18361 taaagtgtta tccctaaatt ttcgtaataa cgaagtcaac tattgtactt gtattgcgta
    18421 gacagggtta acctattatc gaggttaaag tcatatgaca gaattattaa attttttcta
    18481 aactttgtct cattgcgtaa tttagtgtat gaattaacat aaagggttta agataacaaa
    18541 aagtgcaaaa caatattgac tttttcgttt atataaaata aaatgaaagc ggttactacc
    18601 ctgttaaata tgggaggatt aagttatgaa agacttatta ttcaatggat atagcaacta
    18661 tacaacagct aacaatattc aaaagtgcgc tgtagaagaa tgtgaattag gtaatgtagg
    18721 aacatcaatt tcattaagtg ttacttattc agcttctgtt tcatggacaa tcacttggag
    18781 tgtataattt gaatttataa aagtattttg attttattct aaaataatag ggtggtgacc
    18841 tttatgttga atgttcatat agaattttta aagttaataa attctacaga taaatcagat
    18901 attaaaagtg aaattaggaa aattatttcc aaaaagaaaa gtgagaaaga tataaaaaat
    18961 ctagaaaatt taataatttc gttaagggta ggaaatacta aatacatttg gaatgaagag
    19021 cgtaatgaaa ttgttttgaa tgaaaaaaat atttccggat gtataaaaat gtatttggat
    19081 gaagagaatt tattagatag gttcttcatt ctaccaacta tacctgagat gaccaatata
    19141 aaagattttg aaagagccat aaaacaaata aatgtggatt atgaaatcca attagttaga
    19201 aaaaaagatt tgttaaaagt acaatcagag gcaaatagaa atacaccgtt agcaatttct
    19261 tctatggtaa agattattgt agcagcctgc atttataaag aaattagtga aggaaatatt
    19321 gaattaagta gtacaattaa aatcaaagca gaggatataa gtgttttgag tgcgggaata
    19381 ggcaaacaaa atattggtga tttatttacc atcgaagaat tgttaaagtt attattgttt
    19441 gtttcagata atacagctat ggatattttt atcgattatc tgggggagga taaaattgaa
    19501 aagtttttaa attttgaaaa atctaaagta gagaacaaag gatataaatt taattttcct
    19561 ttaacaaaaa atatttatac tgaagcatgg tgtacggaat caaattccga acaacaatgg
    19621 agaaattctg caatgaaaaa ggttgtttgg acagagggat tagactattt tatcgactta
    19681 gattacgtaa ggtatagtat gaattacctg ctgaataata gttggatacc ttgggatgat
    19741 attcaaaata ataatgtaat ttataaagga ggatcagcac caggagtatt atcatgtatc
    19801 tggtctacga gaaacctgga aaaagaagat tttttgcaat ttttgtttgt gataaataaa
    19861 agagccccct tctctttatt ggaagaatta tacatttttg gatgtgctaa taagctgttg
    19921 gatttttatg gagttttgaa ggtaaggtga tttatatatt tgagttagta tgaaacatga
    19981 aaaagaaatg agggatagaa atggaagtta gggaaggacg aaatattaat aaaaaagtag
    20041 agaaaggagg aaaatgtctt tttaaaaaga cattagtagg tccgaaaagc gatgcacaaa
    20101 ggagatttga taattgttta aaatgggagg aatcacgcaa aaatatgcca cagataaatt
    20161 ctcctaagct tgtggattat gataatgatg aattagattt atactatgag tggttagaag
    20221 aaggaacatc acttgaagat tttttgctag aaaagtcaga tgatttggaa aacaagataa
    20281 aggtagcatc aaatgcatta gcaattatac acacaacaag caattggata tcggatattg
    20341 ataaagaaaa aagtctacca gatagacgtt cgcttatgat agcaataagc aagtatgatt
    20401 atgctagttg tactggcgca gagttagagc tgtttgcact tttacatcaa gataaaaaat
    20461 ttatagagtc attgtttgat gaaaacaatg aaaccgatga atgtttgtgt catggagacg
    20521 taagactgga tcaattcata tggtatcaaa ataaaatgta tattattgat tttgaagagt
    20581 tacgaatcgg agatggaaca agggatcttg caggaataat aggttcgatt tattttaact
    20641 gtttgttaaa aacttttagt gaaaccacac aagagacttc agatgaaaaa gagatagagg
    20701 cacaattcat tgaaagaggc atggcataca tagaagaaat gattccaatt atgaagtcag
    20761 catatgaagc ctattcaatt gtaaaaccaa ttaatttaat gaatttatca ataaatattg
    20821 gatggtttat tattgagaga atcatgagta gagctaaata ttcttttaag ttgtcagcta
    20881 cagacaaagc gattttagga attggaagag aaataatatt gtctccaaat aagtttgagg
    20941 aaatttttaa acagtagaat aaagggggaa ttttaatgtt acataatact tctattgaaa
    21001 cattattgac taaaatgaat ttagagatag acttaaataa agtgacaata gcaaatttta
    21061 tatataaagg tgttttagag aaacctaaag cagaattaat acaatggttg tataaagtgt
    21121 tgcacacagg taatatagag gtgaataaga atcaaattat aaaatcatta aatgatttag
    21181 atagtaatat aattaaacgt ttaaaagacc ccgaaattaa aatgccggtt caaaagcaag
    21241 aagttcataa taaaagctat cctataatac acggtgtaag aatacatgaa gatgtaggaa
    21301 tagaccaatt tataagtgtt ccgtgctttc gtccgaatct tacgcctggc ttttttatgt
    21361 ttgtaaacac agaaaacggt ttgcacaatg gtaatgtgaa aaggcattat atttatgcag
    21421 atacgcctga atatggaata gaaacatggg tgaactgtgt tgaaaaatta atgagtgaaa
    21481 aggcatcatt ttcagcaaaa gtgctttcat cttcggccaa ttatccaaga aatgacgcgt
    21541 tagtttttta tagtagtaaa gatacacaga aagttcaaga aatattagtt aatgaaataa
    21601 ataaaaaccc tatcagaaat attaaagggt ctttgttggc aaaaaaatta gtgcataatt
    21661 tatatgtagc agatgaacct attcagagac aaggtatgca tcaaagtttt ggagagcatc
    21721 gctgtaatgc aattgcagat gcgatacaag atcattttat tacaggtgta gagtttaaat
    21781 tattattaaa gcaaaggtta ttatcatata atataaatat agatgatata tctaaaaatt
    21841 attgaaatat ataaatctgg gaggaagatt gtatgactat taaaattttg attcctataa
    21901 ttatattgat aattatatat ttaatagtat gttatcatga tttgtacaaa attaatatgg
    21961 tcaaatattt acctaaatgg gtgtggagta ttattattat tatttctatt cctttaggcg
    22021 gagtaattta ttttctatta ggaagagaaa cacgaggtga gaatggtgac tagtttaatt
    22081 catgttaaca atttatctat tcactttgga gattttattg cactagagga tattacttta
    22141 acttttaaaa agactaatgg agtgattggt ttaataggac ctaatggtgc tggtaaaaca
    22201 actttaatca gcgcaataat tggacaatta aagtttcata agggttttgt aaatgttaat
    22261 catgaagatg ttgcgtattg tccagatgta ccatcttttg agtcttttct gacacctaaa
    22321 gaagtattag aacaaacaat aaggttgaga ggaaaaccgg tcaaaaatta taaaaaaaaa
    22381 atattagatg tattaaaaga tgtggactta actaaaagtc aaaataaact tgtgggaggc
    22441 ttttctcgtg gtatgaggca aagattggga attgcatctg cactggtttt agatccaaag
    22501 ataatatttt tagatgaacc aacaagtgca ttggacccat ttggacaaaa agatgtttta
    22561 caattagtgg ataaagtggc aaaaaatcac gtagttgtta tatcaagtca taatttaaaa
    22621 gatgtagaaa aaattgctaa ggaaataatt gtactcaatg aaggtagact tatttacaaa
    22681 ggaaatttaa atagttttgc tgaagaaaaa caaaagttgg caataataga attttctgat
    22741 tctaaaatat ctgaaaattt tgacgtgatt ttacaagaaa ataacatttc tcatagttta
    22801 gttgataaaa caataaaatt tgaaaattat gaaataaaaa aagtgctatc cctagtcaat
    22861 tcttatgccg attatattgt aaggatagaa agagagatat tttctttaga agatgcattt
    22921 gaagcacatg taaaaaaatc gcaataaaag tgagaggata gagatatggt taaattagaa
    22981 ttaatgacat ggattagaag caaaaagttt cttgttattt ttgtggtttt tttattttct
    23041 ggttttacat ctccgcttat cgcttattat tcaaatgata ttataaatag ttttagtaat
    23101 agtaatacga agattatatt tgcagaccct aaatggacag atttaatttt atcttacttt
    23161 aaaaatgcat cacagctcgt gatgtttata actgcatata taatcggaga tacgtgtaga
    23221 tttggaaaag ataaatcgat tcagttatat tataaaacta gagcacgtaa ttcaggtaga
    23281 attctatatc caaagattct tgtaagtcta gtagttgtga ctttaggagc gcttctcggg
    23341 agtttaagtg cattgtatac aacgtggatt tattttgatg attttaattt aaatcacgct
    23401 gttcaaggtc tttttgttca aattatagga attttgattt tttcaacttt tagtggggta
    23461 attgcttttt ggataaattc agcatttgtc gctgctttaa ttgtagaaat tttcatattt
    23521 attgcaatgt ttttcgcctc cattgaagaa tttcaaaaat ggtcacctgt tacattacta
    23581 aaaccacaga atgttttgat agaaggaata aatactacca atttatggta tccgttgatt
    23641 attggagggt tagtttgttt gatactaatt attgttagtt tttatcgccc acttagaaga
    23701 aaaactatta aatgaggaat gatttgatga tagctaaagt tactaatgtt cagaaatccc
    23761 ttaatgacag ggaaattatc aaaaacgttt cgttttcttt agaaaaagga tctataaatg
    23821 ctattttagg gccaaatggt gtaggaaaaa caacgactgt tcgattatta acaggtttac
    23881 taatacccac caaaggtaca gttgaagtgt tcggcacatt aacgactgat aaagattttg
    23941 accgagtaag ggaatttatt ggagtgcaaa atgatggtaa cctctatgaa agtttaacag
    24001 tttatgagaa ccttagactt tgggcgatat tttacaatat accaagtata caaattcctg
    24061 aacgcataga taagttattg catcattttg atttgcacga aagaaaatat agcaaggtag
    24121 gtacactaag taaaggtcta aaacaaaaag tctcaattat aagagctatg ctacataatc
    24181 caaagttatt aattttagac gagccaacct cgggactgga tccatcagct gcagaagaac
    24241 tgattagata tattcaaaaa attgtatatg aaaaaaatac aacagtattt atgtgtacac
    24301 atcaacttca aggattggaa aatatagcag ataatatttt tattatgtat aatggtgagt
    24361 ttattgtatc tggaaattca tctgaacttt taagttctga atggccagga tcgacttttg
    24421 aaatagtttc aaataatccg ttgaaatgtc ttgaattatt aaaaggtttt tctgaagtta
    24481 taattgctag tgaagcgtat gatgaagacg tagtaagggt gtctgtaaaa gaaaaagcaa
    24541 tgatatcaaa aataattgag atgttggtat acgagcgcat taatatttat gaggttacca
    24601 aagttgaacg tgaaattaaa gaattttatt tcaagaaaat aggtgaagtc aaacatggtg
    24661 aatattaaat atgtatgcaa tattgtaaga aaagatatct tggaggcaaa aggtgaacaa
    24721 ggaataattg tatcagtttt ggtcattccc tttattttta gcatattatt gccattacta
    24781 gtaatagtgg gaggaacaaa taatacatta gtaaatttta tcggaggcat tcatattttt
    24841 attgaacaat tacctaacga tatatttcca ataaatattt ctaaaaataa tgcaataatt
    24901 tatgctgttt taatgtattt ctttatacca ttttttttat taataccagt tattgtttca
    24961 acaatattat cgacctctag ttttacagga gaaagagaaa agaaaactat tgaaggatta
    25021 ctctacacac ctattacaaa taaagaattg atgttaggta aaatattatc atctttttta
    25081 ccagccataa ttgtaacatg gatttcaata acagtttttg gtgttattat aaacctattt
    25141 tcaataaata caatggaaaa attagtattt ccaaatctta attggataat aataggggga
    25201 ttaatagcgc cattgattac ttttctatcg atttcgttag taatagcaat ttcacataag
    25261 atgaaaacta gtaagtcagc acagtcagtt tctatgttac taatactacc tattattgga
    25321 tttttaattt cacaggcaag tggattgttt ttatttggta ctaaaatctc attaatttta
    25381 gtctcagttt taattgtctt agatttttca atatatttaa ttattgctaa aaagtttaat
    25441 agggatagat ttataactaa agtataggag gagggtttgt cgtgaaagtt ttaacgatag
    25501 taaatacaga tttagtttca gaaaaagatg ttgaaatgct tccagatatt agtattgcag
    25561 gatctaaaat aaaatgtggt atcattgata ttccaaaacc aacattcaat gaatgtgaaa
    25621 aagaaaatga ccattttgtt ttggttaagg ttttggcttt ttcttgtaat tacagagata
    25681 aagcaatcat attaaaatca gcattgaaaa tgcaaggagc attgaatttt caagcggctc
    25741 catttgcatt tttcggctca gattttgtag ctactgttgt tgcgaaaggg aaactagtgg
    25801 gaaattttga aattggccaa cgtgtaattc ctaactgcgc ttatccagaa tctccttttc
    25861 caggtgttgc tgcaggtgtt gtgactaacg aagcttcaaa aggatggttg agaattcata
    25921 agtctaaact cattgctatc ccagataata tggatgatgc tattgcagcg agcttttcta
    25981 ttggtggtca aacatcaact agtatggtta ggaaagttga cctaaaaaaa ggagagcgtg
    26041 tattagtttt aagtggaaga tcaaatacgt caatgtttat tattaataat ttacttgaaa
    26101 agaatgttga tactacagtg ttaacaacat catcttggtc aaaagatgaa atttctctaa
    26161 tatctcctgc aaaacttgtt aaagtggaaa agtcattttt gaaatggaaa gatcacgagg
    26221 atttgggaac ttttgacgtt gtttttgatc ctttttttga tttgcattta gaaaaagctg
    26281 ttaattcact aaaaacttat ggtcgctata ttacatgtgg atataaaaat cagcataata
    26341 aattcatgga agacactgat aaatttaata ataataattt aaagagtatt attttaaaag
    26401 ttatgataaa taatatgtct attattggta actgcattgg aacaagtgaa gacttagaaa
    26461 aagcacttgc caattataat cctagtcgtt ttattgttcc gattgatggt tgttattctg
    26521 tggaagaagg ggataagttt gtagcacgaa cgtataataa tagaggaaga ttaggtaaag
    26581 ctgttttagc ttattcatga acaaatgtgg attgcattcg agtaatagaa atctattagt
    26641 ggatcttaaa atacaagtta tgagattttt ctgaataaaa tctatctata agtatataat
    26701 atgttatttt taaggtgcgc taggcataga caacatcttg acgcttaact ctgttacaag
    26761 gctaggtaga tgaaactgtt agataaagac atgagtgtcc attgcaaagt ggaaactgaa
    26821 ggaagtcgga cattaaaact cgtactgatg aacaaaaaca tcatactaag actatgtgga
    26881 atggataaat ttgcgaaaca agttgaagtc ctatactacc agagttctac atagtaaatg
    26941 atgcggtgac ataagtggga aagtttacat gttacaggga tgttgtcaac aaagacgaaa
    27001 gtagaatcat agcagtcatg cttttaaagt tcttgagttg tctagtgagc aaggtgtaaa
    27061 tggcggttat aaaatgtagg aaaatggcag tttgaaaata ctgtttttct tacatttttt
    27121 attttctaaa atatataatc atgccttaac tcaatatctg aatggaggct gtttgattga
    27181 gacttgatac atacgaagga gtgctacttt acatcacgaa aggaataaaa ccaaattatg
    27241 ctgagctagg tagacagtat caaaattaaa accctataaa accctcataa acgaaaaatt
    27301 agaattaggt tgtacggcta tggcgattta taaatatatt ttttaaaaag gatatcaatg
    27361 caagtatacg attctaggag aatattgtag ttgacggaaa aggaagtcga atatcaagtt
    27421 aagaaaacat ttaaacgtgc tattaagtta gcacgtttcc ctaaggttaa atatttaagt
    27481 gactttgatt ttaagttgca accaagtatt agtaaacaag aaatacttac attaaaatcc
    27541 atacattttc tagagaagca catcaataca tgcttcttaa gtaatagtgg tgttggtaag
    27601 acacgcctac aatatcgcta ggcatagaag ctcgtaaaca aaatatcaaa actcgcttct
    27661 atacttttaa agaattaatt gaacgcttaa ctacatcaga aaagaaagaa ataatcaata
    27721 aaaccttaaa acaattacac acagaattga actgcttatc attgatgaga ttggctatac
    27781 ccccatctca aaagaaagag cagatctctc ctatcaactg atgtcactaa gatatgaaat
    27841 gaaatccaca atcataacga cggatatccc ttttctagtt gggaagattc atttagtaac
    27901 aaaatagtgt cagcagccat tattgataga cttattcacc attcaaaaat atttaaaatt
    27961 acaggcgatt cataccgact taaagactat aaaagtgaaa aaagtttaaa catacgtcat
    28021 tcttaaaccg ccaaaaaacg atattttcaa accgctattg atactttttg aaacacatct
    28081 taaattcttt atttatgtta tgcttttatt aactaaaatc gtataaaaaa ggagtagctc
    28141 aatgattatt ttacttgcca ttttaggttt tctttttata cttttgctcg tgattcatat
    28201 gtttaaatta gatgttttga ttgccaatat cgactttgaa caaattgatg aacgctatcg
    28261 tgatactgtt cggagacgat ggttgatttg gacggaaatg atgatagcta tattatttgt
    28321 ttggagctta ggcttttatt tgtatcattt ttataccgtt gttttcatta taggtgtttt
    28381 ctgttgggtt atcatatatt caatcgggtt gcattatctg acaaaaaaat ttaaaaatag
    28441 gtgaatcaca aaattccagt tgataatgat aatctttatc aattataatg aaagaagtta
    28501 tcaattgaac agtgggtctg tatcgaattg acaatcaagg tacctcattt ggagatagat
    28561 acaataaggg tgcagtcgca atcagggcga atgcgtaaaa ggagatgaag tccaatgttt
    28621 atggcagaaa acaagttgac attacaaaaa ggtacagctg aggcaacaat gaagcgattc
    28681 caccgtcgtc aaggtattga gacgattgat ggattcatcg aaatgtatgt aacacaaacg
    28741 aatggtttaa aagaatatga tgaagtgaaa attttaacgg tttggcaatc tgaggctgcg
    28801 tttcgtgaat ggttaggctc agatgtgttt aaagcgtcac ataaaaatgt taggcagcat
    28861 catgaagaga aagaaagccc gattttgaag aataaagtgt ctacatacca aattggttat
    28921 cattatgaaa aagcacatgc atagatagat ggaaagggaa cggaataaaa aatttgatgc
    28981 tattgatgca atgttttgtt taacttgccc tctcgctacg attggttttt gattgccttt
    29041 atggctgatc tttcctatgg gctggccctt caactcaatt cggcttgatt atagtgtaca
    29101 tttggtggta gccgaattgg attttgggag cagtacagaa atctcatgtg taacaaagat
    29161 ttcgttgtac tgcccccgca aggctgacta gacttctcaa aagcatgcgc attgagaagt
    29221 cagacagcta ctgcgttaaa cggtagccac ttttaaagtt aaatgacgtt gtttaacctt
    29281 taacttatcc ctcaggagtc tcagccttcc gggcaatctt acatcaaata cagtaacata
    29341 gggcaaattt atggaattaa gaaaagcaat agcatcaatt ttttatccaa ttcatcttct
    29401 tttttatgct gtttgataat ctttaatgaa tagataaagg ctaggaaaat aatgtcctag
    29461 cctgtttttg tgttttgatt ttttgtatga ttgtcctttc cttaacctag aaatactaca
    29521 aatcgctcaa aatagattat aatgatatct aaagatgcga ggtgtagaaa tgaaaacata
    29581 tatagaacga gatggacgta caattcagaa acactatttg acattaaatg gccatcgaca
    29641 aggaatcatt attgaatcaa gaggcacagc taaaccgata ttactcgttg tccatggcgg
    29701 cccaggattt ccgctttatt ccttttttag agcacatcat attgacttaa ctgatcgtta
    29761 tacagttgta ttttgggatc aacgtggcac aggtatgtct tatacccgtg aaacagttga
    29821 aatggcggat ttaatctctg actcgtatca actgattcaa tttttacggc atcattttca
    29881 acaagaacaa gtgtatttga tgtgtcactc attcggtacc attattggaa cacatctcgc
    29941 gcatcgctat ccagaatata ttgcagcata cattgggatg gggcaactcg gggacgtatt
    30001 tcataatgag caatgtattt tgcagcattt acgctttcta gcatatgaag aacgcaatca
    30061 acgtgcaatc aaacgattaa gcgcaatcca tttaacgcgt gattttaaca aagattgcca
    30121 atatgaaaag gcaagacaac gctatacggc acgttatcat gtcggttttt caagtcgtgg
    30181 ctattccgtt tggcgcatgt ttcgtgtgat gatgcaaacg ccatattacc gtttgataga
    30241 aagaattaat attgtcagag gtagtttgtc cacgtttgaa catttaacta gtgaaatggc
    30301 acatacgaat ttgaatgata ttgcccagga aataaaggcc ccattttatg ttttacaagg
    30361 ggttcacgac atgcagacga catacgaaga cagtaaagct ttttttgagc atgtcggttc
    30421 tgcagaaaaa cgtttttacg cttttcaaga tactgcgcac gccccatttg tcgatgagcc
    30481 tgaaaaaatg atcgaaatta tgcatgaaat tgttgaccgt cacgtgacgt cataggctat
    30541 acatgaagta tggaggtgaa atcgatgtta cattattcga caggtgaact tgcgaatatg
    30601 tttggactta caaaaagaac cattcagtat tatgatcttc aacacatctt aaaacctgcc
    30661 tatatagacg ataatcaata tcgcatgtat acagagcgtg aggtggaata gttgcgccta
    30721 attttagtga tgaagtcatt aggtctcacg cttaaagaga ttaagcaaat gttgtcagtg
    30781 gatggaacac ttcaaacggt acgtacttta gtgacacgaa aagtagaaga aactgaggcg
    30841 gaaatacgac aacaacaaca gcaactgaaa caaatgaagc aaatgcaaca gatgatactg
    30901 gattcatcac gtgcacctgt taaaaatcta tctgacattg aagatgcgat gaaacaaaaa
    30961 ccacaacatc aacgtctcgt gaaacacatg tttttgatgg gaacgacagc cacattattt
    31021 gaagtgattg gtattggctt gagttggaaa tatcgtcaat tatggccagc cgttttagga
    31081 tttggaagtg caattacagt agcccaaaaa atgacacata cgtactatca gcaagtcagt
    31141 tacatgtgtc caaattgcca acagcagttt aaaccgccat atcgaacatg gttattagcg
    31201 cctcacactt cacaaacaag aatgttaacg tgcccgaatt gtggatttaa agggtattgc
    31261 actgaaattt acgatgcatc aatgaaatta taaaacgata gtaaagtgcg tgacatgcga
    31321 gatgaattgc tgttgcgcac ttttttcgtc tgtgtttcaa aagaagtaac cgaaaatttg
    31381 taagcgcttc aaaaaatccg ttgaattgtg tccgtaaagc gaataagatg gggatgtatg
    31441 gaattttgtg aagagaggaa gtattggcat gaaaatactc gcagttacat cttgtccaaa
    31501 tggtattgca catacatata tggcacaaga aaagttagag caagccgcag cgtcactcgg
    31561 tattgatatt aaagtggaaa cgcaaggggg tgtcggtaca gaaaatgtat taacagctga
    31621 agaaatcgca gctgcagagg gtattattat tgccgcagat agacaagtgg atttatcacg
    31681 gtttaatggt aagccgctcc tgaaagaaag tgtcagagca ggtattcatc aaccggaagc
    31741 cttaatccaa cgtgtggtgc agggggaagc accggtgtat cattcgacag ggcaagctga
    31801 agcaagtgag acatcttcac accaaagcga gaataacaaa aatggcatgc aaatggttta
    31861 tcaacattta atgaatgggg tttcctttat ggtgccattt atcgttgtcg gtgggttact
    31921 cattgcattg gcattgtcat taggtggtga aaaaacagcg acacaaggtt tagtgattcc
    31981 cgatgattca ttttggaaac cgtttgaaaa aattggtgca ttagcgttta gctttatggt
    32041 accgatattg gccggttaca ttgcagtgag tattgctgat aagccaggtc tcgtgccagg
    32101 gatgattggt ggtgcgattg cagcggacgg tagcttttac ggtagtactg cgggtgctgg
    32161 ctttttaggc ggtatcgttg ccggtttctt agcaggttat attgcgaaat ggattaaaaa
    32221 tgttaaagta ccaaaagcga tggcgccgat tatgccgatt attattattc caattattgc
    32281 gtcggtcctc gtcggtatga tttttatttt cattttaggt gcgcccattg cagcagtttt
    32341 tgaatctttg acgacttggc tgaaagggat gcaaggggca aacattgtca ttttagcttt
    32401 aattatcggt gcaatgattg cgtttgacat gggtggtcca gtgaacaaag ttgcattttt
    32461 atttggttcg gctttaatcg cagaaggcaa ctacagcgtc atggggatgg tcgcagtagc
    32521 agtctgtacg ccgccgattg gactcggact tgcgacattt attcaaaaac gtaaattcaa
    32581 ccgtaatgaa attgaaatgg ggaaagcttc atttacgatg ggactcttcg ggattacaga
    32641 aggtgcgatt ccatttgcgg cacaagatcc attacgtatt attccggcga atatgatcgg
    32701 tgcgatggtg gcttcggtca ttgctgcact gggtcatgtc ggtgatagag ttgcgcacgg
    32761 tggacctatt gttgcggtat taggaggcat cgatggggtg ctcatgttta tcgtcgcagt
    32821 attagtcggt agctttgtca cgacagcact cgtgttaaca tttaaaaagc aaccgacagc
    32881 aactcaagcg atatctagaa catcaatatc cacagtgaag gcaaatgacg atacagacgt
    32941 agaagatatg ttgaatccac aagcaatgat tcaaacagca acgcctatgg atagagacaa
    33001 agccattgat acgataatta atcgtttagt gcgtgaaaac tatgtggcaa atgctgcggt
    33061 gttaaaagag gctgtactcg cacgtgaggc cgaatcgacg acagccctcg gtatgcacat
    33121 cgcgatgccc catgcgaaaa caaatgcgat acgtcaaccg attattggtg tacttaaaca
    33181 tgatcaaggg gtacaatggg aaagtttaga cggtacattg ccacaactcg tctttttaat
    33241 tgctgtaccg gaacaaagtc atgatacgca tttaaaagtg ttgcaacaac tgtcgaaaaa
    33301 cttaatgcat gatgacaaac gacaacgatt gttagacaca acgaatgaag cggaattata
    33361 cgagacatta caacgtatca tcaaagcata actgggactt aaagaggctg ggggtgactc
    33421 agtctcttgc tttttgctta ttttcaattt gcaatagaac ttatctttat ttaaaaagtg
    33481 ttcaatacgc gctataatag acacatgtta tagaaaggaa tgatggcatg acagaacgaa
    33541 aatccccttc atctcaaaac atgcgtcatc gtttagtcaa agctggtact gtccttttat
    33601 tggttggtag tggactgcaa atgccttcaa cattgtcaca cgaaatgaca gcgatagctc
    33661 agacagatgc gactgatgat ttgaaaacat tacgtgaaaa tgcagataaa aaagtgaaag
    33721 cgttacaata tttaaatacg gattataaaa atgaatttct tgcgttaatt cgtgaatatg
    33781 atacgtcgtc aaaaaatatt gaagtggttg ttgacgaagc agaagcagcc aatcgtctag
    33841 ctcatgacgc tcaatcggac gatgaaatac aacctgaatt agatgccatt gatgaaaaaa
    33901 ttagcgcgtt aaaggcaaag gttgatgaag gtcaacgaga atcaactgaa gcgcgtcaag
    33961 atgtaacgtc aacagagaca aagagtgctg aatcagaagg aagagagcca tccactgaag
    34021 gcgagagcaa agtaaaggag tcatcttcag cacaaacgat tgtagcacct catcatggtc
    34081 aacaagatgt gagcgcactg aaagaccata ttaagaacga tgtcgataca cttaaacaag
    34141 actatgcaac gcaagacaag caagtgacac cactccaggg cattgacagt gcaatcacac
    34201 gcattgacca tttcgtttca gaaagcgtgg atcacaagtc tgacaattat tttgaagaaa
    34261 aacgtcaaca tttacaaaac tttgaacaag acattaaaaa acgtacggac atttctggga
    34321 ctgagaaggc gactttgctt gatgatgcga aaacggtagc caaccaactg aacgcgcaaa
    34381 atgatacgat tttaactgaa cttcaacagc atgacgataa acgtgcagca gttgaatcga
    34441 tattaggtga gatttttaat gcacaagaag cggctcaacg tgcgaaacag atagatgtta
    34501 aaggtaaaac agatcaacaa ttggcaaacg aaattcatca acaagcggac ggacttatca
    34561 aaacgtcgag tgatgattta ttgttaggaa tgttggaaaa taattcaaat acacaaggtc
    34621 tagtggaaag cattttacga acacgctttg acaaacaaga agcgcacaaa attgccggcg
    34681 aaatcatgca aggcaagcct tcaaatgcag cgatactcga ccgcttgaaa gaccatttta
    34741 aagcgaatgg taaggcgagt ggagatgata ttttaaatgc gttaattaat aatacggatg
    34801 cagatgctga agtgattgaa tcaattctag ggggccgtct taatgcagaa aatgcaaaat
    34861 tgattgccga ccgtgtacag aaagataaaa agaaaacaca tcaaaactta aaggcgattg
    34921 aagacgaact tagtgcgcaa gcgaatcgat tgttaacgtt acggaagcaa ttgcaacaaa
    34981 tccgtcacaa tacgcaaaca gatatgaatg acttgtttgc accgctgcgt cgtattgcaa
    35041 atattctcag tggtggttta aatcgtgacg acattcactc ttcaggtcgt acgaatgaca
    35101 aattgcagca actgttaaat cgtgatcatt cgttgttagg tcgtggtggt gatttattca
    35161 aacatgattt tgcgccaaag ccgaatatcg atccatatca agcgattaat agtcaaacgg
    35221 catcacacgg ctttttagat ggtttatttg atcaaaatgg cgatttcaat ttaccgaata
    35281 caggtgaaat agtgaagcgg acttggctac cgttgggtat tttagtcgtt gcaatcggtg
    35341 tactgatctt aacggtgaga tttcataaaa aaacacgcaa acaataagca cgaaaactat
    35401 gcataaataa ggggaggaga gataaaaatt tttgatgcga ttgatacgat attttgttta
    35461 acttgtcctc aatgctttat ggttttgatt gccattaagg cttccctttc caaaggggtg
    35521 ccccttcaac gcacaaacgc ttgattaaac gggtacattt gttgagctgt taatggattt
    35581 tgggagcatt acagaaatat catgtgtcac aaaggtttcg tcgtattgtc cccgcaaggc
    35641 tgactcggct tctcaaaagt gtaaacattg agaagtcaga gagctactgc gataaacagt
    35701 aaccgctatt aaagaaaaga ggtcattgtc agcagtatgc acgtattccc acaggcgtct
    35761 cagccttctg ggaaatctga tattaaaata ttgaaattga gtgcaagttt atgaaatcaa
    35821 gaaaaccaat agtatccaat ttttatgtcc aattcatcct tattttttga ctgtttaata
    35881 aatataaata aagcaaaacc tgaaaagtgg tagaggcggg gataacttaa tgtccttgcc
    35941 tctaccactt tttaaataaa acagcatgag taacattctt tattcagttg ctaagtcacc
    36001 gctaatgtaa tctaattgtg cggcatcttt tgcatcaatt gtacggaatg aaatgacacc
    36061 cagtcctttg acattagatt ctgatataac gatggaacca tcacgattca ctttctcaac
    36121 gaaggcgacg tgaccgtaat aacgatctgc acctaattca ttcggattaa atactactgc
    36181 actgtgtact tttggcttgc ttgatacgct ataaccttgt gtaagtgcag aataagtcca
    36241 atcagcggca tttcccattg tacctgaaat gtgaatgtca aattgtgcca tacgattgta
    36301 cacataccac gtacattgtc catacggata cggtgagtct gcagatatgg caaatggttt
    36361 gaaagcaccg ccatcgcttt tcgcagtttc gttatcatct ttctcagcta ataaatctgg
    36421 catgtcatct tggtcaaaac gcgttaaatc gtacgcttca attaaagctt ctaacttttg
    36481 gtcatattgt ggatctgtcg catatgtacc aacgagtgct gaagcggcat cgtgataact
    36541 agaactatgg cttttccaaa cgtcttcata gatattcgga ttaccatcga tgcctccttt
    36601 aattaaatct gcataatctt gtaaggacgc tttgtgatcg gggtattttc ggaaagcagc
    36661 atcgatttca tacaattgtt tgccgtctga ttccaaagtt ttgaaatgtg cgctttctcc
    36721 gtgatagctg cctttaatac caaacaagtt gaaataagga tcacgtgata attcacttct
    36781 accagagtca gattctaaaa tcgcttgagc aatcatgata gaggcataga ggtcttcttg
    36841 ttgaccgata tcatgtgcat ctttcgcaat gtcattaata aactcacgtg ttgatgattg
    36901 cgggacgaca cgcattgttc ctgcatcatt tgtagacgta tcagaatcgg gcattgtttc
    36961 aaacagtgtc gtttgacgtg tttgctttct atctgcctcg ttttgatagg attgtttcgg
    37021 tgcttgttct cgtgatgact tgaaagtgtc agggtcagaa acttgcgctt catgtttttg
    37081 cgattttgac gttgaagatg gctcattagc ctctttttgt tgttgatatg catgatgcgt
    37141 ttgttcagct ttttcgctat attcgtctaa cagtgcatca atcaccgcat cattttgatt
    37201 ttttttagtt tgttgatccg aagtcgcgtc gtcacgagtt gatggcgcat ggttttctgt
    37261 ttgtttatct tcggtatccg gtgcatctac cgttgttgat ggcttttcag ttgtactatc
    37321 gtcattcaca ggtggtactt ccgatgtgcc ttctgatgta gctttgcttt tttctgaagt
    37381 tgtcgcatct tcagttgagg gctgttcatt cgaagtatcc gtgttgtgtg aaggtgtaac
    37441 attttcttgg tcattgtctc gctgttcagt tgaaggtgat gccgttgttg cttggtctga
    37501 tgataatgcg tcatcagttg aagttgtcgt atcatttttg ctgtcttcac caccgctcag
    37561 aatcgcttga agttgctcga aaaagtctcg attttcaggc gtcgatgatt gcgcttgttt
    37621 tggcattgat gtcgcgtcat ttgttggtgc tggatatgta tgctgaggcg cgtctgttgt
    37681 ttcatttaat gtagaatgaa acagttggcc aaaccaatct gtatgaggcg acaaagacga
    37741 tttcaactgt gaatccaaag gggatgttat gtcgaaaagg tcagcctttt ttgaatcatg
    37801 ttgttgcgaa gttgttttct cacttgtttt cgatgattct cgtttcgttg tttctttttt
    37861 atctgatgat tgagattgct ttttacggtc gtcacgtgtt tcgtctgacg cgacatcttg
    37921 atcatgatta tccacttttg gatttttagg tccattttca gtttgaggtg ttgctgcaac
    37981 agcccattga ggtgtgacag aagggatgag caatgcagta cttaacaacc ctgtataaat
    38041 gaatttctta ttcaatttaa gactcctttc ttaaaaaaag cgcagtgatt gatgtgtaaa
    38101 atagggttga aatgcacaat gataatggca cgactcgggt cacaagggga agtgacgtga
    38161 tgtgagatta acgtgtttga ttcatcacta tcaaaagcat tccgtttata caaaggtata
    38221 caaaatgcta aagaacttgt tatactaaaa gatgtcttgc atttcgttga tgcgtgttaa
    38281 cttaaaaata aaaataacga aattttgcaa ttgttataca tattttatat tacatgaatg
    38341 aaagtaaata ataaagtgtt tcacaaaata ttgaggtgaa aaaatgaaga atgccatcaa
    38401 actttttctg acggatatta aaaaaattgc taaaacacct ggagcgatgg tgctgatttt
    38461 agggttagcg atactgcctt ctttttatgc gtggttcaac ctcgaagcaa cttgggatcc
    38521 gtactcgaat acagacggca ttaaaattgc agttgtcaac gaggataaag gcgatacagt
    38581 gcgcaataaa aaaattaacg ttgggaatca aatagaagag actttgcgta aagatgacca
    38641 ttttgattgg caaatggtga gtcgagaaaa ggcggatcgg gaattaaaaa tgggaaaata
    38701 ttatgcggcg atttatattc cagaaaaatt cacgcatcaa gtgactggaa ttgtgcgtaa
    38761 agaccctcaa caagctgaag tcgaatataa agtgaatcag aagctgaacg cgattgcacc
    38821 taaaatgacg gatgctggct caagtgaaat agtgagaaat gcgaacaaaa aatttaacga
    38881 gacggtgacg aaagctttat tagatgaagc aaatcgtatt ggcattaaac tagaagacca
    38941 attgcccaac tatcacaaag tcagagatgg catttatgcg gcggataatg cattgccaaa
    39001 aatcgaaaag ttccgtaaaa cattgattta tttagatgaa aatcaagacc aaatcgatca
    39061 atatgcggac aaatttagag cactagatca atataaagat gatgcagtga cagcaaccga
    39121 gcgtttaaat caactgaacg cgagcatccc agccattaac gagcgtgcca aacttattgt
    39181 gtcattaaat caagcgatgc cagacattga gcgtgtgctc caagtggcaa gtggtgtgcc
    39241 taatcatttc ccagagatta acgatggggt ggaccgtgcc attgcaggta cagatcaagc
    39301 acttgttaaa ctgaacgaaa ttcaacagct attgcctgca gtagaacaac gtgtgaatgt
    39361 acttcaaaat ggcgtggacc gtggaagagt agtaaatcaa gctgtaggag aaaatgcgcg
    39421 aaatgcgact acaaccacac cgcaaagtac acgaggtacg gcatatcata cggcagcaat
    39481 gagtacgacg acacaaggag atagtaccaa cgttccagcg ggtcacatca tttcaccagc
    39541 agatgcgcaa acgatgacga cggcttatgg ggatacattg cagcaagtga atcaagcggt
    39601 aacacaacaa cttaaagcga cgtccgctga tttagatacg gcagaaaact taagttacgg
    39661 tattttgagc gccaaagatc caaaacaatt tgaatcgccg ttaaaccacc tcattgcacg
    39721 tatgaataac gcaacgaaaa cgattcgtga ttatagagat tatttagcaa acattgaaaa
    39781 aagtgaaggt gtcgatttat cagatgccca atcacgactc aaaacagtgc aagaagatat
    39841 tgaacaacga acaaagcgtt tgaatgcatt aaaggatgct atctcagcag gcaactctgg
    39901 tcaagcagaa gctgcagatg tattggatag tctatctaaa gcaaaagatc agttaaacgc
    39961 tgttggaaaa taccttagag gagattttac acaaacacta cgggatattt ctgacagatt
    40021 gggcgcagca ttgaatcaag gggcaacgac tttagacaat gtacaacagc gtctgaatca
    40081 gttaaacagt gcgatacgac aagggcagca atttttaact gaagggcaac aacgcttaca
    40141 ccaattaagt gacacgttac ctcgcgtgga agcagcatat attaatgcga tgaaagcagc
    40201 ccaagcttac tttccacaat ttcgtcaaaa ggtcgctgaa gcatccaact ttgtagaaaa
    40261 tgacttacca agagtggaag gacgagtttc tgatgcgact gccacagtga atgaaaaatt
    40321 accagaagca ttcgcacaat atgaccgttt gcgcaatatt ttagatacaa atcaaccaaa
    40381 agcgaaagaa acattacatc gtttggcaga atttgcaaga aatgatttgc cgcaagttga
    40441 agaagatttg caaaaggcag acggtatttt taaacaactc gataaagaga atacgataga
    40501 agatttaatt gacttattgc ggaatgacct gaaaaaacaa gccggtgtca ttgccagtcc
    40561 agtcgatcta caaaaagaga atgttttccc agttaaagat tatggttcag cgagtacacc
    40621 attctatacg gcattggcaa tttgggtcgg cgcattgtta cttgtcagct tgttgtcagt
    40681 gcacaataag catccagagt taaaaccata tttgaccatt cgcgaaacat atctaggtaa
    40741 aatgggactt ttcttattaa tgaatatcat acaagcgacg atcgtctcta ttggggatat
    40801 tgtgattttg aaagcatcga ttgaatcagt gccacttttt attgcgatta gtatgtattc
    40861 tgcactgata tttacaacga ttgtgtatac attagtatca gtattaggaa atccaggtaa
    40921 agcactggct atcgtcttgc ttgtattaca aatcgctggg ggtggcggaa cattcccaat
    40981 tgaagtgaca ccacaatttt tccaaagtat tcacccattc ttgccattct catacagtat
    41041 tgatgcattg agagaagcag tgggtggacc tgtgccacaa attttaacgt ataagttgac
    41101 gatgcttact gtatttggtg ttggtttctt cttagtgggc ttgataggga agccgtattt
    41161 agacccatta gcacaaggat tagcggaaaa ggccgagaag agcgacgtat tggaataatg
    41221 tttttgaaat caggcatatt gtttttggtg gtaactacaa ttgctgaacc gtgctgcgct
    41281 ttccgagacg ccgatctctc aacgaactaa cgcttaattg aactgttata aaagaagcgt
    41341 tagtggattt tgggaacagt acagaaatct catgtgcaac aaagattctg tatgacagtg
    41401 atctttcaaa acacgattct ttgttgagtc gtcaatgttt cattatagca agtgcagtgc
    41461 aaaggttgtg aagccctttt gcactgtgct ttttattttt agaatttgta gttaattgta
    41521 ttttcttctt tttgaggttg gcaatagttg ttgattagta tataatacat atcgaaatac
    41581 taggaattga aaaggggata atcatggagt ttatggacgt gtttgaaaaa tgggcagagc
    41641 gttatgatga aacggtattt aacactggta atgacaatga gtatgaagat gtgtttgacg
    41701 gctacacagc aatgttagag ggcgtggttg cattatcatc gggacgtgta cttgagattg
    41761 gtgccggcac aggtaattta acacagcggc ttatccatca ggagttcgat gtcacagcca
    41821 ttgatccttc agaagacatg cggac
//
