LOCUS       NZ_CP065858            21613 bp    DNA     circular CON 16-FEB-2024
DEFINITION  Bacillus halotolerans strain P1 chromosome.
ACCESSION   NZ_CP065858
VERSION     NZ_CP065858.1
KEYWORDS    RefSeq.
SOURCE      Bacillus halotolerans
  ORGANISM  Bacillus halotolerans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4087194)
  AUTHORS   Cullings,K., Stott,M.B., Bhardwaj,S.R. and Spector,M.
  TITLE     Phylum-level Variation in the Microbiomes of the Basidiomycete Fungi
            Scleroderma citrinum (Pers.) and Pisolithus arhizus (Pers.): a tale
            of two saprotrophs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4087194)
  AUTHORS   Spector,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2020) JQ, NASA-Ames, 5215 Wavecrest Way, Oxnard,
            CA 93035, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Velvet v. 1.2
            Assembly Name                     :: NASA.Piso.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/16/2024 03:00:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,218
            CDSs (total)                      :: 4,134
            Genes (coding)                    :: 3,973
            CDSs (with protein)               :: 3,973
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 88 of 161
            Pseudo Genes (incomplete)         :: 96 of 161
            Pseudo Genes (internal stop)      :: 27 of 161
            Pseudo Genes (multiple problems)  :: 40 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:53:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 668165
            Orig. end                         :: 689778
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065858.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from 5215 Wavecrest Way, Oxnard
            California 93035.
FEATURES             Location/Qualifiers
     region          1..21613
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="3"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21613
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21613
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11613](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11613
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(141..155)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(233..3919)
                     /locus_tag="I7X10_RS03335"
                     /old_locus_tag="I7X10_03335"
     CDS             complement(233..3919)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="I7X10_RS03335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03335"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_185848503.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHQSNKHSQTTYEDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRSVLINLWREALQAHQNPLEAWKSIVENPDKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVITYGPDRNIGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQKTERFIEYAKQYTD
                     FPFFVTLTKEDGVYTAGRFLHAKDIGRQTEHDQWKPAVWNERTSAFAIPQGTMGSRWDG
                     QKKWNLHMIDEETGESIEPRLSVLGIEDEIGTVRIPYFSNEGNRVLERDLPIKKLALDN
                     EDVYVTTVFDLILANYGVNRGIGAKSACSYDDPEPFTPAWQEQVTGIKKEMVINIAREF
                     AQNAIDTEGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPVSDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFDKNGIDLYKEAEKAGAKTTKDVADYVARQLQEKKLKFAIEDP
                     DNEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSNLAEEVDMKPVKEAVAAPLLHDTMQEMAQPLGKIKDWSKGECEAV
                     PGKTMPNIQVVERDYKQIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEVTT
                     DSVAKGCPNISEAKQAAEAVLTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAADADIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3985..4000)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(4075..4551)
                     /locus_tag="I7X10_RS03340"
                     /old_locus_tag="I7X10_03340"
     CDS             complement(4075..4551)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="I7X10_RS03340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03340"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_024123206.1"
                     /transl_table=11
                     /translation="MNQCDYLFFLKQLPMFNEVPLSIVETLLNNGTFIRGSCDQDPSFL
                     HSQSIYIVLKGSIRFIDSRLPEGSQTVALWEKGDVFPIDQKGGMFLSPFISVRTSEDIL
                     MLNIPFYILKKIMSYYPQLQMNFLVMLQQNVFFSYELFLRYMHRSQDENAEPDS"
     misc_feature    complement(4609..4624)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4694..5413
                     /locus_tag="I7X10_RS03345"
                     /old_locus_tag="I7X10_03345"
     CDS             4694..5413
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="I7X10_RS03345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03345"
                     /product="YwiC-like family protein"
                     /protein_id="WP_198098134.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFCLGMVKGGAVLWHIPLFLGWLFLYLA
                     VYPVTLALKKKQIKPYQKWIISYSFPACSFLLAAVIHKPSFIWLAFSLLPLFLIHVYYA
                     RQKNERALLNDFAGVLFFCTGGLASNWLGTETLDGWAWFIFAQSALFFIGSSFYVKSVI
                     REKNNRVFAYWSWGYHLILPLLSAALGGGWAVLAFIPSSLRAWFFHGKKWPVQTIGILE
                     IVNASFFFAIMCIWLTR"
     gene            complement(5446..6162)
                     /locus_tag="I7X10_RS03350"
                     /old_locus_tag="I7X10_03350"
     CDS             complement(5446..6162)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="I7X10_RS03350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03350"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_101859805.1"
                     /transl_table=11
                     /translation="MNFLSVRTSDKDLISSDLHQLLESISTKRKIKKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTADGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKSRLEKELIHNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VNRSDGILINIALTNQDLAKFCAAARESVNRMLGDLRKQGVISIEDSGKIVLHQRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6273..7460)
                     /locus_tag="I7X10_RS03355"
                     /old_locus_tag="I7X10_03355"
     CDS             complement(6273..7460)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="I7X10_RS03355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03355"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_010332275.1"
                     /transl_table=11
                     /translation="MINRQHFQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARIIFMISFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAITTFAAPVIAQAAGWKSTVQ
                     MYMVLLALFALLHFFFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEQFDLSPADAGLRTAGFIAVSTLLRPAGGWLADKVSPLRILMFVFAGLTLS
                     GVILSFSPTIGIYAFGALTVAVCSGIGNGTVFKLVPFYFSKQAGIANGVVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVIVIWMYWQERMKTHTERSGHSVN"
     misc_feature    complement(7525..7540)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    7537..7552
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.43"
                     /tool="antismash"
     misc_feature    7543..7556
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.45"
                     /tool="antismash"
     misc_feature    7544..7557
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    7545..7558
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            complement(7594..9264)
                     /gene="argS"
                     /locus_tag="I7X10_RS03360"
                     /old_locus_tag="I7X10_03360"
     CDS             complement(7594..9264)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="I7X10_RS03360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03360"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_024123210.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIRAAVLKAGLAEESQIPNVILETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEEIVASFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGDAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLAKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIISIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRVDLENFRVPFDVWYSETSLYQNGKIDKALDALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLVNVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSPIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9261..9689)
                     /locus_tag="I7X10_RS03365"
                     /old_locus_tag="I7X10_03365"
     CDS             complement(9261..9689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="I7X10_RS03365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03365"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_198098135.1"
                     /transl_table=11
                     /translation="MKQETPITIHVKSVIEDDGNEEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGQVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLGEEQGRISIAYDMHVGDEQQHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="I7X10_RS03370"
                     /old_locus_tag="I7X10_03370"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="I7X10_RS03370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03370"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="I7X10_RS03370_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="I7X10_RS03370_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     misc_feature    complement(10171..10187)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.25"
                     /tool="antismash"
     gene            10267..11613
                     /gene="albA"
                     /locus_tag="I7X10_RS03375"
                     /old_locus_tag="I7X10_03375"
     CDS             10267..11613
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="I7X10_RS03375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03375"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_198098136.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1070.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.3e-28,
                     bitscore: 97.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.1e-07, bitscore: 30.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 1e-06,
                     bitscore: 26.6, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.2e-44, bitscore:
                     149.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.4e-06, bitscore: 25.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.3e-20, bitscore: 71.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.5e-10, bitscore:
                     37.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 9.5e-09, bitscore: 33.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMLMDGQRTAEQILEEQCAKYDESPEDHKGWYYDMLSMLLNKQVIQLENRARF
                     HKIATSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIDQFKKTADMLYDN
                     GVLTCEITGGEIFVHPNANEILEYVLKKFKKVAVLTNGTLMRKESLEMLKAYKQKIIVG
                     ISLDSVQSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSPLVHKLWKAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10282..10560
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_I7X10_RS03375_Subtilosin_rSAM_RRE.1"
                     /evalue="8.70E-31"
                     /identifier="RREFam018.1"
                     /label="I7X10_RS03375"
                     /locus_tag="I7X10_RS03375"
                     /protein_end="98"
                     /protein_start="5"
                     /score="97.1"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMLMDGQRTAEQILEEQCAKYDESPEDHKGWYYDMLSMLLNKQVIQL"
     gene            11626..11787
                     /gene="albB"
                     /locus_tag="I7X10_RS03380"
                     /old_locus_tag="I7X10_03380"
     CDS             11626..11787
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="I7X10_RS03380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03380"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_024123213.1"
                     /transl_table=11
                     /translation="MSPAQRKMLLYILSFIFVIGAVVYFVKSDYLFTLISIAIAIIFGM
                     RARKADSR"
     gene            11784..12503
                     /locus_tag="I7X10_RS03385"
                     /old_locus_tag="I7X10_03385"
     CDS             11784..12503
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="I7X10_RS03385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03385"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_024123214.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYEQDNVILENVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGHFTLCGIEADAGMPQKTSDELKIRRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFNSLAEEFHFSQYTNRRISELSLGNRQKVVLMTGLLLGAPLFILD
                     EPLVGLDVESIEVFYQKMQEYCKAGGTILFSSHLLDVVQRFCDYAAILHHKQIRKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12496..13809
                     /locus_tag="I7X10_RS03390"
                     /old_locus_tag="I7X10_03390"
     CDS             12496..13809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="I7X10_RS03390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03390"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_198098137.1"
                     /transl_table=11
                     /translation="MNNLFPILSLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESTLGKTYITLALLFMNAYMVFLSVTSQWKESYMKLSCLLPISSRNFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLYWLGRFSFFTVYSIIFGVLLSNLFVKKRR
                     TALLLHAAAFTCVCFSAALMPAVTIPLCAIHMLWAIVIDFPSFLQAPQQQSKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMGAFSGFFSFQMMNTGIADQHVVYIVISALLLIC
                     SPIALLYSLEKNDRMLLITLPIKRRTMLWAKYRFYSGLLAGGFILIAMIMGLISGRPIS
                     LLTFLQCMELLLAGAYIRLISDEKKPSFSWQTEQQLWSGFSKYRSYVFCIPLFLATLTG
                     TVISLAVIPIAGLIIVYLLQKQDGGFFDTSGKRERLGS"
     gene            13799..14962
                     /locus_tag="I7X10_RS03395"
                     /old_locus_tag="I7X10_03395"
     CDS             13799..14962
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="I7X10_RS03395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03395"
                     /product="insulinase family protein"
                     /protein_id="WP_198098549.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 7.2e-05,
                     bitscore: 20.8, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLTTDQFSTISIAASFLKPIESVAEPEEETIYFYGAAAHQK
                     QNIINTFGYAAGRRFMYSANLFFDRQLKTYGTRMIHPLYAEGFHTDAVLNTFVDMSSFP
                     ASLSASAAEKAKAELLLKMEKTFADPFSYSAARLAEEAFGNPMYGTAMFGRKDKLMAVH
                     PKRFLDASEFIADLFSQQKQLNILGNIQSCDVQGHAPQASAMSAVRKPVNQDIFETETR
                     STAGPSVMTLGFDCGDMKDVRDYLAIQLIDGLLGKYGHSALFRHFREKDLAVYHVITRY
                     DIMSNMLLVSVCTDQLHENEIPPRVLEAVSHFHADEPELKKAQQFLINEILLQFDSPEG
                     LLAYMGILRRFSCKKEDLLDSISAVTCRDLLQFIKNLTYIGAHVVRG"
     gene            14968..16245
                     /locus_tag="I7X10_RS03400"
                     /old_locus_tag="I7X10_03400"
     CDS             14968..16245
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="I7X10_RS03400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03400"
                     /product="pitrilysin family protein"
                     /protein_id="WP_198098138.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 1.8e-12, bitscore:
                     45.4, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 9.7e-06,
                     bitscore: 23.6, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKEAFFQQLDERTDIRYTDKGMKIFRLQFPRAHLRLCNVKTGFG
                     SRDIRLQSETGGRMLPYGTAHFLEHLLFWHNGRNLYSDFFEHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDEQIIAQEKAVITSEIETALLNHQLHYHYQLIQMLS
                     PASPAAVFPAGRKKDIEALTICDLQEAYAAAYQPHRMTLFLIGGPEDAETLLPSQLRLE
                     KRSGSRSDRKIVPACPPLSPKEVKGDLERPEDTWTGIQVGALPEENGLLTLKLYWYIAS
                     RILFHMDSPFFQEIRQTYRLNIQSLSADVHLSEDGGFLILHSKGAHSSAYIDVASYYIT
                     QQKNRTEAWLEYGKDSLVNAIIYDSDYARKCFEWAAECEQYDCSFLGLYRTIQQMNSHD
                     FLALIEAMVSSNKAVIHVPQKEVMRQ"
     gene            16242..16943
                     /locus_tag="I7X10_RS03405"
                     /old_locus_tag="I7X10_03405"
     CDS             16242..16943
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="I7X10_RS03405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03405"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_198098139.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLAAMAAYSFGWFDSGAEAAGRYVQLIKNDAARL
                     GLLACAASVLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQHRKLCSRYADDVK
                     LLRDSYRGIRQSYVMAAVLYQVIVFGCMFEIVKAVPFSFHTPPSITMGLAVLLILYLLF
                     YMRTYFLQLFQHGNLFRKVLVGALTGAGIGWMLSFTISELLFLIILAAIQQIGSFVYKR
                     ISYRSPASLDL"
     gene            complement(16950..>17416)
                     /locus_tag="I7X10_RS03410"
                     /old_locus_tag="I7X10_03410"
                     /pseudo=""
     CDS             complement(16950..>17416)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="I7X10_RS03410"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="I7X10_03410"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="ASREVPFQVPIEGFVVDPAEAVSAVTWSTDVMNGELCRRV"
     gene            complement(17510..18862)
                     /locus_tag="I7X10_RS03415"
                     /old_locus_tag="I7X10_03415"
     CDS             complement(17510..18862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="I7X10_RS03415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03415"
                     /product="YncE family protein"
                     /protein_id="WP_198098140.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAEAAQDCLCFCEEETSREAMFQAPIELPEGFVVD
                     PAEAVANVTWNADSLSCVSERCLIETGPEPDEIGVQFAVRLQGTVTLLVSVSPVRNQYG
                     QGEGAISVIHNVEIDQVVYYSDEPDDCPDVSDITIENLVVVPPFYGSPLSVTGTIVLAP
                     EPEPVYAFTANPDDQSVSVIDTNTHTVVTTISLPYQPTRVEKTPDNTSVFVLHYYDRVI
                     TVINQDTLSVTASILLDQPPESISFIPGHEFFYVVAGGAIYVIGIETLTVERSIPFEGF
                     DVAIDPNGLFAYLLGFGSVQRLDLNTGEVTGTIERDLIVNALETGWPERYLYVLEQEFF
                     FNYLTVIDLNTFTISSTQELEYEGEYGMFKSGSGVYLFDDFTHNLYSVSPSGAGVIGNL
                     PQSARDFAFTPNGEFLYATNFIEQSITVYNTDDYSVETVISLGVSPSDIAI"
     misc_feature    19042..19058
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19091..20236
                     /locus_tag="I7X10_RS03420"
                     /old_locus_tag="I7X10_03420"
     CDS             19091..20236
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="I7X10_RS03420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03420"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_024123222.1"
                     /transl_table=11
                     /translation="MTSVISSSSVGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLENMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYILAIQFFKKAESKLTFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYNEQTTYDIRMIQCQSLFGANFLDLKQYDKAIAHFQKAYTLAEAAQQPQLMG
                     RTLYNIALCKQNQHSLESAIEYVKKSIHVFEESKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGREYSIAAGDTVYLMEFEFLESLYLSGPDEEAIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASTYFLKVEEARQHIQGGVNLYEMEV"
     gene            20220..20339
                     /locus_tag="I7X10_RS03425"
                     /old_locus_tag="I7X10_03425"
     CDS             20220..20339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="I7X10_RS03425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03425"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_024123223.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFVTVEVSNSSTEHFDVAQRAMI"
     gene            complement(20445..21317)
                     /gene="speB"
                     /locus_tag="I7X10_RS03430"
                     /old_locus_tag="I7X10_03430"
     CDS             complement(20445..21317)
                     /EC_number="3.5.3.11"
                     /GO_function="GO:0008783 - agmatinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="speB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391629.1"
                     /locus_tag="I7X10_RS03430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I7X10_03430"
                     /product="agmatinase"
                     /protein_id="WP_101864909.1"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIASRPEWEEADAILYGMPMDWTVSYRPGSRFGP
                     GRIREVSIGLEEYSPYLDRDLADLNFFDAGDIPLPFGNPQKSLDMIEEYVDSILEKGKF
                     PMGMGGEHLVSWPVMKAMYKKFPDLAIIHFDAHTDLRVDYEGEPLSHSTPIRKAAELIG
                     PENVYSFGIRSGMKEEFEWAKENGMHISKFEVLEPLKKVLPKLAGRPVYVTIDIDVLDP
                     AHAPGTGTVDAGGITSKELLASVHEIARSEVNVKGADLVEVAPIYDHSEQTANTASKII
                     REMLLGFVK"
ORIGIN
        1 ggttttcggg cctgatttca gctcgagctt tccttttttt aaggtccagc cgcctttata
       61 tttgtcctga tcctcccatt gcttcggata gccgatacct ggctttgttt ctacattatt
      121 gaaatacata tattcggcac cggaacggtt tgtccatgtg tttttgcagg tgacgctgca
      181 cgtgtggcag ccgatgcatt tatccaagtt catgaccatt ccgatttgcg ctttaatctt
      241 caagccaatc gacctccttc agcttgcgga tgaccacatt cagatcgcgc tgattccccg
      301 tagggccata gtagttaaag ccgtagctga gctgggcata gccgccgatc atctgtgtcg
      361 gcttaacgtg aatccttgtc ggactgttat gggtgcctcc gcggttattg gtcagttttg
      421 tgccgggcac gttgatgtgg cggtcttggg catggtgcat aaacgccatt ccttttggta
      481 tccggtgaga tagaaccgct ctggctacga caacaccatt tcggttaaag cattcaatcc
      541 aatcgttatc tttgatatcc gcatctgccg catcatcttt attcatccat actgtcggcc
      601 cgccgcgaaa tagcgtaagc atcggcagag aatcaaaata catgctgtgc acggaccatt
      661 tattatgcgg cgttaaataa ttgagaacga tttctttgcc ctcttgatct ggccgtttgc
      721 ttaagaaagg gcgatgctgg aggatcggtt taaaggtcgc catcgtttcc ccgaactcca
      781 tcatcagctc atgatcgaca taataggatt gtctgcctgt cagcgtacgc caagggatta
      841 atttttccac atttgtcgta aacggcgaat accggcgccc gcctttttcc gagcctgtaa
      901 atgccggaga tgtgatcacc gttttgggct gagccgtgat ttgttcgaac gtaaagcatt
      961 cttcctcccg ctcttcagcc agatctttca gcttcagatt cgtgatgtct tcaagcgatt
     1021 cccatgcttt tacggcaact tttccattcg acgtggacga aagagttaaa acggcttctg
     1081 ccgcctgctt ggcctcgctt atattcggac atccctttgc gacactgtct gtggtgactt
     1141 ctcccagcct ttttttgagt gattcgtatt catcggcaat cgaccagctc atgccttttg
     1201 ttccgcttgg ttttaaggcg gcgtttgggc cgagcgcggt cattttatga aagatttgtt
     1261 tgtagtccct ttcaacgact tgaatgttcg gcattgtttt ccccgggacg gcttcgcatt
     1321 cgcctttgct ccagtccttg atttttccga gaggctgcgc catttcctgc atcgtgtcat
     1381 ggaggagcgg tgcggcgaca gcttctttta ccggcttcat atcaacttct tccgcgagat
     1441 tggagacggc ttttgataaa gccttgaaaa tatcccagtc cgacttcgat tcccaaggag
     1501 ccgaaatagc cggggcaaag gggtggataa acggatgcat atcagtgctg ctgagatcgt
     1561 gtttttcata ccatgtcgcc gccggaagca cgatatcgga atacaaggcg gtaccggcca
     1621 ttcggaaatc gagattgatt aacaaatcga gctttccttc cggtgcctgc tcgcgccact
     1681 tgatttcttc aggacggata ctgtcgctgt cgtcattcat caagccgttc gtcgttccca
     1741 agagatgctt gagaaaatat tcatgccctt ttcccgaact ggagatcaga ttcgccctcc
     1801 acacgaacag gtttctcgga aaattcgctt cattgtcagg atcttcaatg gcaaatttca
     1861 gttttttctc ttgaagctgg cgggccacat agtcagcaac gtcttttgtt gtcttcgctc
     1921 ccgctttttc agcttctttg tacaggtcaa ttccgttttt atcaaatgtc ggataagacg
     1981 gaagccaccc cagtcttgcc gccagcacat tgtagtcggc gtgatgcttg tagcgggagg
     2041 atgccgcgat cggagatgct aagtcactga ccggctgatc ctcgtagcgc cactggtcag
     2101 tcgcaaaata gaaaaaggaa gtgccgtttt gcagctttgg cgccccctcc caatccttag
     2161 cgttggcgat cgtctgccag ccttcagcag gacggagttt ttcctgtccc acataatgag
     2221 cccagcctcc gccgtttacg ccttgggcgc ctaccagtaa aacaagattt aacaccgccc
     2281 ggtagatcgt gtctgagttg aaccagtggt tgatccccgc tcctacgata atcatggacc
     2341 ggccctctgt atcgatcgca ttttgggcaa attccctggc aatgttaatg accatctctt
     2401 ttttgatccc tgtcacctgc tcctgccagg ctggcgtaaa cggctcagga tcgtcatacg
     2461 agcaggctga ttttgccccg atcccccgat tcacgccgta gttagccaaa atcaagtcaa
     2521 atacggttgt gacatacaca tcctcattgt ccagcgccag tttttttata ggcagatctc
     2581 gctcaagcac tctgttcccc tcatttgaga aataagggat tcgaaccgtg ccgatttcgt
     2641 cctctatgcc gagcaccgaa agccggggtt caatcgattc gcctgtttct tcatctatca
     2701 tgtgcaggtt ccatttcttt tggccgtccc agcgggagcc cattgttcct tgcgggatcg
     2761 cgaatgcgct tgtacgttca ttccacaccg caggcttcca ctgatcatgc tccgtctgcc
     2821 gcccgatgtc ctttgcatga agaaaacgcc cggccgtata cacgccatcc tctttagtta
     2881 gagtgacaaa gaacgggaaa tccgtatatt gctttgcata ctctatgaaa cgctctgtct
     2941 tctgattaac gtaaaactcc tgcaggatca catgacccat cgccatcgca agcgcgccgt
     3001 ctgttccttg gcggatgctc agccagtcat ctgcaaattt agaggattcc gcgaaatccg
     3061 ggctgattga gatgacctta gcgcctttat agcgggcttc tgccaaaaaa tgcgcatccg
     3121 gcgtcctcgt taacggcaca ttggagcccc atgtgatgat atagcctgag ttgtaccaat
     3181 cactgctttc cgggacgtct gtctggtcgc cccagatttg cggggatgcc gggggaagat
     3241 ccgcatacca atcatagaaa ctaagcatag ggccgccaat caaagacata aaccgcgagc
     3301 ctgacgcatg gctgatcatg gacatagcgg gaatcggaga aaacccgata ttccggtcag
     3361 ggccgtatgt tataaccgta tacagcagag aagcagaaat cagcttcagc acctccggcc
     3421 attcagcgcg cacaaaacca ccctttcccc gcgcctgttt ataggacttc gctttatccg
     3481 gattttcaac gatcgatttc catgcttcca aagggttttg atgagcctgc aatgcttccc
     3541 gccacaaatt gatcagcaca ctgcgcacgt acggatattt cacacggagc gggctgtaaa
     3601 tataccatga aaaactggcc ccccgcggac agcctctcgg ttcgaaatca ggcatatccg
     3661 ggcctgttga aggataattc aaattttgac cctcccacgt gacgatgccg tttttcacgt
     3721 atatattcca gctgcaggac cctgtgcagt tgacaccgtg ggtggagcgg acgaccttat
     3781 cgtactgcca tctgtttctg tatacattct cccaatcacg atcttcatag gttgtttggc
     3841 tatgtttatt tgattgatgc tcaataggag agaaatagtt taatctccta aacaacggac
     3901 tcattttctt ttttttcatg aatatttcac tccttccgag tcaggtattc taaattcact
     3961 atatacagag gcaggatgtt tccttgtgaa ctatgtcaca cactcccctt ttttcacaga
     4021 aagttcacat gaggaagaag gaatggaaat accgaacaaa aaacccggtt ccttttagga
     4081 atcgggctca gcgttttcgt cctgagatct atgcatgtat cgcaaaaaca gctcataaga
     4141 gaaaaagaca ttttgctgga gcatcaccag aaaattcatt tgcagctgcg gataatagga
     4201 catgattttc tttagtatgt aaaaagggat attgagcata agaatgtctt cggatgttcg
     4261 gactgaaatg aatggagata agaacatccc gcctttttga tcaatgggaa acacatcgcc
     4321 tttttcccac agcgcaacgg tttgcgaccc ttcaggcagc ctgctgtcaa taaaacgaat
     4381 actgcctttt aatacaatat aaatggattg agaatggaga aaagatggat cctgatcaca
     4441 tgaaccgcgg ataaacgtcc cgttattcag caatgtttcg acaatggata gaggcacttc
     4501 attaaacata ggaagttgtt tcaaaaaaaa taaatagtca cactgattca tagggaagcc
     4561 tcctgtgcta aggatacctt tagtgtagcc cggccgatcc atgacagcag tgatgtattt
     4621 cacagtgata tgatgaatgt cacttattgg cggtattttt gcttttataa tgaaacaaga
     4681 aaggagtgtt tcgatgaagg cgcttattcc gaagcagcac ggcgcttggg ccatgctgct
     4741 gattccgttt tgcctcggta tggtgaaggg aggagcggtt ctttggcata tccccctatt
     4801 tttgggctgg ctttttcttt atttggctgt ttatcctgtt acgctggcat taaaaaagaa
     4861 acaaatcaaa ccctatcaaa agtggataat ttcttacagt tttccagcct gcagcttttt
     4921 gcttgccgcc gtcatccata agccgtcttt tatctggctt gccttttctt tgctgccgct
     4981 gtttctcatt catgtgtatt atgcccggca aaaaaatgaa cgagcgctgc tgaatgattt
     5041 tgcgggcgtc ttattctttt gtacaggcgg actcgccagc aactggctgg ggacagaaac
     5101 tcttgacggc tgggcatggt ttatttttgc acaatctgct ttgtttttta tcggaagttc
     5161 attttatgtg aagtcggtga tccgggagaa gaataataga gtatttgctt actggtcgtg
     5221 gggctatcac ctgatcctcc ccttactttc cgcagctctc ggaggtggat gggccgttct
     5281 cgcctttatc cccagcagtt tgcgtgcatg gttttttcat ggaaagaagt ggcctgttca
     5341 aacgatcggc attcttgaaa tcgtcaatgc gagcttcttt ttcgccatca tgtgtatttg
     5401 gctaacaaga taaaaacaag gacatattgc tgtccttgtt tcctcttaat caatattaca
     5461 aatctctaac gggcaatttt cgcactcaat ctcacaccgt aaatagtccc gctgatgcag
     5521 tacaatcttt ccggaatcct ctattgaaat aaccccttgt ttgcggagat cccccagcat
     5581 gcggttgacg ctctctcttg cagccgcgca aaattttgcc aaatcctggt ttgtcagggc
     5641 aatgttaatg agaatgccgt cactccggtt caccccatag ctgtttgaca agcggatgag
     5701 ggtggagtag agcgcccctt ttttgccatg aaggagaaga tctctgattt tggattgaat
     5761 tttgcgcaaa tgggtgctca tccatttcat aaattcaaat gtcaaagcac cgttgtggat
     5821 aagttccttt tcaagtctgc ttttattgat gacgagcact tcgccatcct ccagcacttt
     5881 tgcactgagc atatatctcg gttcttctgt gaaaagtgtt aattcaccga caatatcatt
     5941 tttttgacag attctaagcg tcaggtcttt gccgtcagcc gtcagcttcc cgatttcaat
     6001 gagtcctgac tgaatcagat aaagctcttc tgcatccatt ccttctcgaa acaggtatgt
     6061 gtgttttttg atttttcttt ttgtgctgat ggattccagc aattgatgaa gatcactgga
     6121 aataagatcc ttatcagatg ttcgaacaga gagaaagttc atgagctcac ctcgaagaaa
     6181 agtcacgttg tgtatctatt gtaacgtgaa ttcatttgcg cttttcagaa aaaacttaca
     6241 atctcgtgaa ttcccaaatc gccggcggcc cgtcagttta cgctgtgccc gcttctctct
     6301 gtgtgtgttt tcattctttc ctgccaatac atccatatga caatgacaaa gcttgctaat
     6361 gcgacttccg aaagcgccat aaatccgatg gcgtattgtc ccgtcgcctg aaatacactc
     6421 gccagaatca gcggagggaa aaagccgcct aatccgccca tggcagacac aactccgttg
     6481 gcgattcccg cctgcttaga aaaatagaaa ggaaccagtt taaaaaccgt cccgtttcca
     6541 atcccggagc acaccgcaac cgttaacgcc ccaaaggcat aaatgccgat cgtcggcgaa
     6601 aacgacagga tgacgcccga taatgtcagg ccggcaaaga caaacatcag gatgcggagc
     6661 ggactcactt tatcagccag ccacccgccc gccggcctga gcagcgtgga tacagcaata
     6721 aaacctgccg tccgcagccc ggcatccgca ggactcagat caaactgctc aacaagaaag
     6781 tttggcagat agattgtaaa agcgacaaag gcgccaaacg taataaaata aaagagactc
     6841 agaaaccaca gcacatgatt tcggtaaacg gctttgattt gagtctttac ggacaccttt
     6901 actttcttct catgccggtc accgaagaaa aagtgcagca aagcaaataa agccagcaga
     6961 accatataca tttgcaccgt acttttccac cccgccgctt gagcaatcac gggagctgca
     7021 aatgtagtga tcgcggttcc gatattcccg gcaccgtaaa taccgtttac aacgccatgt
     7081 ttttctttag gatagtactt cggaagagat gtaaccccaa tggaaaaaac ggctccccca
     7141 atccctaaga aaaaaccgcc cgcgattaaa tcaaacaggg aatctgcaat actgatccaa
     7201 aatacaggga ataaaagcaa tataaagctg atcataaaaa tgatccgcgc gccaaacctg
     7261 ttggtcaaat accccagcgg aatgcggaga agcgatccta atataacggg tatggccgtt
     7321 accaaggaaa tttcgccttt gctcaaatga atatctaatg tgatttggga aataagtgac
     7381 gaaatcagca cccaaaccat aaaccctgcc accaagctta atgactgcag cgataattga
     7441 aagtgttgac ggttaatcat tcggcttgcc cctttcactg attcaataat cagccttatc
     7501 atacaaaaac tcggcgagga agattgtgaa ctatatcaca cgatttttta acaaaaaagg
     7561 acaaagccct ctggctttgt cctttcagct tgattacatt ttttcaggag ccgatacgcc
     7621 gatcaattga agcgcgttgt tcagcgtgat ttgcgttgct ttcattaaag ctaagcgcgc
     7681 acggcttttc tcttcgtttt cagggtcgat gactttctcc gcattgtaga agctgtgcag
     7741 agctgaagcc aagtcataaa tataattcgt cacacggtgc ggaattcgtt tttccgccgc
     7801 ttccgccact gcctctggga aaccgccgat tgttttcagc agatcatatt ctttttctga
     7861 ttgaataggg ctgaaatcaa ggtctgccgc cggcttaagt ccttgctctt ccccttggcg
     7921 aagcatgctg caaatgcggg catgtgcgta ttgcgcataa tacacagggt tttcgttaga
     7981 tgttgataca gcaagatcca agtcaaaatc catatgcgta tcagcgctgc gcatcgcgaa
     8041 gaaataacgc acggcatcaa ggccgacttc gtcaatcagg tcgcgcatcg ttaccgcttt
     8101 ccccgtccgt ttgctcattt tcattttctc gccgtttttg taaaggtgca cgagctgaat
     8161 gatttctact tccaacgttc ctttttcata gccaagcgct tcgattgccg ctttcatacg
     8221 cgggatgtag ccgtggtggt cggcgcccca tacgttgacc agcttatcaa agccgcggtc
     8281 aagcttgtcc ttatggtagg cgatatcagg aagcaggtat gtgtatgtgc cgtccttttt
     8341 gatcagtacg cggtctttgt catctccgaa cgttgtggaa cggaaccaag tcgcaccgtc
     8401 ttcctcatag acatggcctt tctcacgcag cgcgtccagc gccttatcga tttttccgtt
     8461 ttggtacagt gatgtttcag aataccacac gtcaaacggc acgcggaagt tttccaagtc
     8521 tacgcgaagc ttctccagct cgtatttcaa accgtactca cggaaaaatg cgaggcgttc
     8581 gctttcttct tcgttgacga aacggtcgcc gtattcctca gcgagacgct ttccgattga
     8641 aatgatatcc tcaccgcggt agccgtcctc cggcatcggt ttttccagtc caagcgcttc
     8701 aaagtaacgg acttctacag aaagcgccag gttgttaatc tggtttccgg catcgttaat
     8761 gtagtattcg cggctcacat cgtaacccgc ttttgcaagc acattgcaca aggaatcgcc
     8821 gacagccgca ccgcgcgcgt ggcctaagtg aaggtccccc gtcggatttg cagatacgaa
     8881 ttccacttga acgcgttcgc cgtttccgat gtttgtttct ccatacgcgt ctcccgcttc
     8941 caatacagac gggatcagct tcgttaaata ttgattgttc atatagaaat tgataaaacc
     9001 aggaccggcg atatcaagct tttcaataga agcctttcct ttatcaaaag aagcgacaat
     9061 ttcctcagcg atttggcgcg gcgctttttt cgcgattctc gcgagctgca tcgccatatt
     9121 tgttgaataa tcgccgtgtg ttttatcctt cggtgtttct aaaatgacat ttggaatctg
     9181 gctttcttca gccagtcccg ctttcagaac ggctgctctg atttcttctt tcagcacgtc
     9241 cttcatttgt tccgcaatgt tcatgcgtga gttcctccct catacgtgat cgtcatatta
     9301 tgtaaatgct gctgctcgtc tccgacatgc atatcatatg cgatactgat acggccttgt
     9361 tcttcgccga gatcagattg aatcgatttt gtgctcgttt tcagctcaag ctcaccaaat
     9421 gacattttat atttggcgat tgtggaagct ccagttacga aacgctggtt cattttgaca
     9481 gcgcctgatc tcatgacaag cacttcgcct tcgcttactt ttacaatcgt tttcacttgg
     9541 cctaagtcgt gttcttcata ataagataga tacactttat tctgtttcac atagtaaaat
     9601 ccggtagtgc ggaattcgat cacttcttcg tttccgtcat cctcgatcac agatttcaca
     9661 tggattgtta tcggtgtctc ttgcttcatt ctgacacgtc cttttcatct ttccactttg
     9721 acttgaatag tataatcatt cggtttgtaa acttcaactg cttctatctt accatcattg
     9781 ctcatcagat ttgaagataa acctcagaaa aagcaattcc tttatagaag agaaaatcat
     9841 accactgatt acctttagga aatattacat ttttccgaat tctaccgttt acaattcaca
     9901 ttttcttcaa aatatatgta ttgaaatggt aatttgatag ttttaatata aaagtacatc
     9961 aaagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgcgcaa catgctcaat cggagccgct tgtttagtgg acggacctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctctggggat aaggttctcc
    10141 ggaaaagggc atagtaaatt actatgccct ttttaactaa aatacaaatt ttaactaaaa
    10201 cctacttctt ggttatacat acacagtgat ttttatattt gaatcatatg tataggggat
    10261 ggtattttgt ttatagagca gatgtttcca tttattaatg aaagtgtaag agtccaccag
    10321 ttgcctgagg gcggtgtgct ggaaattgac tacttgcgtg ataacgtctc gatctctgat
    10381 tttgaatact tagatctcaa caaaacggct tacgagcttt gtatgctgat ggacggtcaa
    10441 agaacggctg aacaaatttt agaagagcaa tgcgcaaagt atgatgagtc gccggaagac
    10501 cataagggct ggtactatga catgctcagc atgcttttga acaagcaggt cattcagctt
    10561 gaaaaccggg cccgctttca caaaatcgcc accagcggaa gcaatgaatt tccgatgccg
    10621 ctgcatgcca cctttgagct gacgcaccgc tgcaatttaa agtgcgccca ctgctattta
    10681 gaaagctcgc cggaagcgct cggcaccgta tccattgatc aatttaagaa aacggctgat
    10741 atgctgtatg ataacggcgt tttaacgtgt gaaatcacag gcggcgaaat tttcgtccat
    10801 ccaaacgcca atgagattct tgaatatgtg ttaaagaaat tcaaaaaagt cgccgtctta
    10861 accaacggaa cgctgatgcg aaaagaaagc ctggagatgt taaaagccta taagcaaaaa
    10921 atcatcgtcg gcatatcact ggatagcgta cagtccgaag tgcatgattc atttagaggg
    10981 agaaaaggct cttttgccca aacctgtaaa acgataaaat tgttgagtga tcatggtatt
    11041 tttgtcagag tcgccatgtc ggttttcgaa aaaaacatgt gggaaatcca cgatatggcc
    11101 caaaaggtgc gcgatctcgg ggcgaaagcg ttctcttaca attgggttga tgatttcgga
    11161 agaggcagag atattgtcca tccgacgaaa gatgccgaac agcaccgcaa atttatggag
    11221 tacgagcaaa atgtcattga tgaatttaaa gatttgatcc cgatcattcc gtatgaaaga
    11281 aaacgtgcgg cgaactgcgg cgccggctgg aaatctattg tgatcagccc gttcggagaa
    11341 gtacgcccgt gcgcactctt cccgaaggaa ttttcattgg gaaatatatt tcatgattca
    11401 tatgaaagca tctttgactc ccctcttgtc cataaattgt ggaaagcgca ggcgccgcgg
    11461 ttcagcgagc attgcatgaa agacaaatgc ccgttcagcg gctattgcgg aggctgttac
    11521 ttaaaagggc tgaactccaa caaataccac agaaaaaaca tctgctcctg ggcgaaaaat
    11581 gaacaattag aagatgtggt ccagcttatt taggagggaa acaatttgtc accagcacaa
    11641 agaaaaatgt tactgtatat cctttcattt atttttgtca tcggcgcggt cgtctacttc
    11701 gtaaaaagcg attatttgtt tacgctgatt tccatcgcca tcgccattat tttcggtatg
    11761 cgcgcgcgga aggctgactc gcgatgagca ttttggatat acacgatgta tccgtgtggt
    11821 acgagcaaga caacgtcatc ttagaaaacg tagatttaca tttagaaaaa ggcgccgttt
    11881 acggactgct tggggtaaac ggcgccggaa aaacgacgct gatcaatacg ctgaccgggg
    11941 taaaccgcaa tttcagcgga cactttacgc tgtgcggcat tgaagcggac gccggcatgc
    12001 cgcagaaaac atcagatgag ctgaagatcc gccgctactt tgctgccgat tatccgcttc
    12061 tatttacaga aattacggcg aaggactatg tttctttcgt tcattctttg tatcagaaag
    12121 atttctcaga gcagcaattt aacagtttgg ctgaggaatt tcacttttcc caatacacaa
    12181 accggagaat ttccgagctg tccctcggca acaggcaaaa ggttgtgttg atgaccgggc
    12241 tattgcttgg ggctcccctg tttattttgg atgagccgct tgtcggctta gatgtggagt
    12301 caatagaggt cttttatcag aaaatgcagg agtattgcaa ggcaggcgga acgattttgt
    12361 tttcttccca tttgctcgac gtggtgcaga gattttgtga ttatgcggcc atccttcatc
    12421 acaaacagat ccggaaggtc attccgattg gagaggagac tgatcttcgg cgtgaatttt
    12481 ttgaggtgat cggccatgaa taacctgttt ccgattctgt cattgctgtt caaacagctt
    12541 tacggccgcc aaggaaaaaa agacgccatt cgcatcaccg cagggcttgc cgttctggcc
    12601 ttgtttgaaa tcgggctgat ccgccaggca ggcattgatg aatcaacctt aggaaaaaca
    12661 tacatcacgc tcgcgcttct gtttatgaat gcgtacatgg tgtttctctc tgttacatcc
    12721 caatggaagg aatcttacat gaagctgagc tgtctattgc cgatctcttc ccggaacttc
    12781 tggctcgctc agagtgtggt tttgtttgtt gatacttgct tgagaaggac gctcttcttt
    12841 tttatattac cgctgttctt attcggaaac ggaacgctgt caggagcaca aaccctgtat
    12901 tggctcggca gattttcgtt ttttactgtc tattcgatta ttttcggcgt tttgttaagc
    12961 aatcttttcg tcaaaaaaag gagaacggca ctcctgctgc atgcggcggc attcacctgc
    13021 gtgtgcttca gtgcggcttt gatgcctgcc gtgacgatcc cgctatgtgc gattcatatg
    13081 ctctgggcta ttgtgattga cttcccttca tttttgcagg cgcctcagca gcagagcaaa
    13141 atgcattctt ttatgcggac atcagaattt tcgttttata aaagagaatg gaaccggttt
    13201 atttcctcca aagcgatgct gttaaattat atcgtgatgg gggcattcag cggcttcttt
    13261 tcgtttcaga tgatgaacac cggcattgcc gatcagcatg tcgtctatat cgtaattagc
    13321 gctctcctgc tgatctgctc accgattgct ttattatatt ctcttgaaaa aaatgaccgg
    13381 atgctgctga tcacgcttcc gattaaacgc agaacgatgc tttgggcgaa atatcgcttt
    13441 tattccggtt tattggccgg cgggtttatt ttgattgcca tgattatggg cttgatcagc
    13501 ggccggccga tttcactttt gacttttttg cagtgtatgg aattgctgct ggcaggggct
    13561 tatattcggt taatttcaga tgaaaaaaag ccgtccttca gctggcagac ggagcagcag
    13621 ctctggagcg gtttctctaa ataccgttcc tatgtatttt gtatccctct ttttttagct
    13681 actttaacag gcactgttat ttccttggca gtcattccga ttgccgggct gatcattgtc
    13741 tatttactgc aaaaacagga tggtggtttt tttgatacaa gcggaaaaag agaacggctt
    13801 ggaagttaac ctgctgacga ctgatcaatt ttcaaccatc tcgatcgccg cgagctttct
    13861 gaagccgatc gaaagcgtgg cggaacctga agaagaaacg atctattttt atggcgcggc
    13921 tgcacaccag aagcaaaaca tcatcaacac tttcggctat gccgccggcc gccgcttcat
    13981 gtattcagca aatctctttt ttgaccggca gctgaaaacg tacgggaccc gcatgattca
    14041 tccgttatat gctgagggat ttcatacaga tgccgttctg aacacctttg ttgacatgtc
    14101 ctcctttccg gcttctcttt ctgccagcgc agcggaaaag gcaaaagctg aactgctgct
    14161 gaaaatggaa aagacattcg ctgacccgtt ctcctattca gcagcccgtc tggcggagga
    14221 agcctttgga aacccgatgt acggcactgc catgtttggc cggaaagaca agcttatggc
    14281 tgtgcatcct aaacgttttc tggatgcgtc ggaatttatc gctgatttat tttctcagca
    14341 gaaacagctg aacatattag gaaacataca gtcctgtgat gttcagggac atgccccaca
    14401 ggcgtctgcc atgtctgctg taagaaaacc cgtgaatcag gatattttcg aaacagagac
    14461 acgcagcaca gcaggtccgt ccgttatgac acttggcttt gactgcggag acatgaaaga
    14521 tgtccgcgat tatttagcca tccagctgat agacggattg ctcggcaagt acggccattc
    14581 cgctttattt cggcattttc gcgaaaaaga tctggccgtt tatcacgtga tcacccgcta
    14641 tgacatcatg agcaatatgc tgcttgtttc cgtatgcacc gaccagcttc atgaaaacga
    14701 gattcctcca agagttttgg aagctgtatc gcatttccat gcggatgaac cggaattaaa
    14761 aaaggcacaa caatttttaa tcaatgaaat cctgctgcaa tttgattctc ctgaaggact
    14821 cttagcctat atgggaatcc tgcgccgttt ctcttgcaaa aaagaagacc tgctggacag
    14881 catctcagcg gtcacgtgcc gcgatttgct gcaattcatc aaaaatctta catatattgg
    14941 agctcatgta gtaaggggat gagagagatg gaaaaggaag ccttttttca acagctggat
    15001 gaacgaaccg atatcagata cacagacaag ggaatgaaaa tattcaggtt acaatttccc
    15061 cgcgcccatt taagattgtg caatgtcaaa accggctttg gaagccggga tatccgctta
    15121 cagtcagaaa ccggcggccg gatgctgcca tatggcacag cgcacttttt agaacatctc
    15181 ctcttttggc ataacggccg gaacctgtat agtgattttt ttgaacacgg cgctctgttg
    15241 aatgcgttca ccacttacac tgatacaaat ttcatgttta cctcattgcc ggatcggctc
    15301 agacaaacca ttccaatcct gcttgacgct ttatggaacc actcgtttga cgagcagatc
    15361 attgctcagg aaaaagccgt gattacaagt gaaatagaaa cggcgcttct caaccaccag
    15421 cttcattacc attatcagct gatccagatg ctgtctcctg cctcaccagc cgcagtcttc
    15481 cccgcaggca gaaaaaaaga cattgaggct ctgacgatct gtgatctgca ggaagcctat
    15541 gctgccgcct accagcccca tcggatgacg ctgtttctga ttggcggccc agaagatgcg
    15601 gaaactcttt tgccttctca gctcaggctg gaaaagcgct ctggcagccg ctctgacaga
    15661 aagatcgtcc ctgcgtgccc tcccctctca ccaaaagagg taaagggtga tctggagcgg
    15721 ccggaagaca cttggaccgg aatacaagtc ggggcgctcc cagaagaaaa cggacttttg
    15781 accttgaagc tgtactggta cattgcctct cgcatcctgt ttcacatgga ttcgccgttt
    15841 tttcaagaga tccggcaaac gtaccgcttg aatatccaaa gcctatcagc ggatgttcac
    15901 ttatcagagg atggcggctt tttgatcctt cacagtaaag gggcgcattc ttccgcatac
    15961 atcgatgtgg catcttacta tatcacgcag cagaaaaacc gtaccgaagc ctggcttgag
    16021 tacggcaagg attctttagt caacgcgatc atatatgaca gtgattacgc gcgtaaatgc
    16081 tttgaatggg cggcggagtg tgaacagtac gattgctcgt ttctcggcct ttaccgcacc
    16141 attcagcaga tgaattctca tgatttcttg gctctcattg aagcaatggt ttcttctaac
    16201 aaagcagtca ttcatgtacc ccagaaagaa gtgatgagac aatgaaaaaa agcactgtct
    16261 ttactttatt attgctgctt gcggccatgg cggcttattc cttcggctgg tttgactcag
    16321 gtgccgaagc cgcaggccga tatgtacagc tgatcaaaaa tgacgctgcc cgccttgggc
    16381 tgttggcttg tgccgcttcc gtactgatgc tgcccgcctt tctctatctt cactacgtga
    16441 cgcaatctgt caaaaacatg acagcagctt ttcagaaact cacacagtct catcaaagct
    16501 gctgtgactt tcagcatcgc aagctgtgca gccgttatgc cgacgatgta aaattgctgc
    16561 gcgacagcta taggggcatc cgccaatcat atgtgatggc tgctgtattg tatcaggtca
    16621 tcgttttcgg ctgcatgttc gaaatcgtta aagccgttcc cttcagcttt cacacgcccc
    16681 cttccattac aatggggcta gcggtgttac taattctgta tttattgttt tatatgcgaa
    16741 cgtattttct tcagctattc cagcatggaa acctgttccg aaaagtgctt gtgggagcgc
    16801 tgacaggagc cgggattggg tggatgctca gttttactat aagtgaactg ctgtttctga
    16861 tcatcttagc tgccatccag cagatcggat cttttgttta taaacgaatc tcttaccgca
    16921 gccctgcttc tctcgatcta taaaaacatc tacatcgcaa tcgcggacgg accggcgcca
    16981 accggaatga ccgtcacggc tgaatcatca ctcgtgcggt acacggtcac tgcattgtcg
    17041 ccgggctgtg ccgcgtaaat gtattgattg tcgggcgtta ctgtaatgtc atagacatta
    17101 ggaagagaca cgtttgcgat gatcctttgt gcggcagtat taacgacata tacattgtta
    17161 atgagaaacg gttcactata aggctctaga aaataagccc tagtactatc cagagaaaat
    17221 acaattgtcc tcaaagtttc aaatagacgg tcaaagtcac ctcccctgct caagggtgac
    17281 aaactgatct ctgttacacc cttcggcaca gttcaccatt catcacgtct gtactccatg
    17341 taaccgcaga gactgcttcc gcaggatcaa cgacaaaccc ttcaatcggc acttgaaatg
    17401 gcacttcacg gctggcatct tcatcacaaa aacagaaaca attttcctgt aaaacagaaa
    17461 aatcattctt tttcatgatt tcacatccct tttagaaatg catagttgat taaatcgcaa
    17521 tgtcactcgg tgaaacgcca agcgatatga cagtttccac agaataatca tccgtgttgt
    17581 aaacagtgat gctttgctct ataaaatttg ttgcatacag aaattcgcca tttggggtaa
    17641 acgcaaagtc tcttgccgat tgcggaagat ttcctattac gcctgcacca cttggactga
    17701 cggaatatag attgtgagtg aaatcatcaa acaaatacac ccctgatccg ctcttgaaca
    17761 ttccatattc accctcatac tccagctctt gggtgctgct gatcgtaaat gtatttaaat
    17821 caatcaccgt caaataattg aaaaagaatt cttgttctaa tacataaagg taacgttcag
    17881 gccaacccgt ttctaaggca tttacgataa gatcccgttc aatagttcct gtcacttcac
    17941 ctgtgtttaa gtccaatctt tgcactgaac cgaaaccaag cagatacgcg aacaatccat
    18001 ttggatcaat tgcaacatca aaaccttcaa aaggaataga cctttcaaca gttaaggttt
    18061 caattcctat cacgtatatg gcaccaccgg cgacaacata aaaaaattcg tgtccaggta
    18121 taaaagatat ggattccggc ggctgatcca gcaaaataga agctgtgaca ctcaatgtgt
    18181 cttgattgat gacagtaatg acacgatcat agtaatgcaa aacaaacaca gaggtgttat
    18241 ctggcgtctt ttctaccctt gtaggttggt atggaagaga aatcgtcgtc acaacagtat
    18301 gagtgtttgt atcaatcaca gaaaccgact gatcatctgg attcgctgta aacgcataaa
    18361 caggctccgg ctccggggcg agcacaatcg ttcccgtcac cgataaagga ctgccgtaaa
    18421 atggcgggac gacaacaagg ttctcgatcg taatgtcact gacatccgga caatcatccg
    18481 gttcatcaga ataatagaca acttgatcga tctctacatt gtgaatgaca gaaatagccc
    18541 cctccccttg tccatattgg tttcgcacag gtgagacact gacaagaagc gtaacggttc
    18601 cctgcaggcg gactgcaaat tgaacaccga tttcatcagg ctcaggcccc gtctcaatta
    18661 agcaacgttc actgacacaa gaaaggctgt ctgcattcca cgtgacgttt gcaacagctt
    18721 cagccggatc aacgacaaac ccctcaggca attcaatcgg cgcttgaaac atcgcttcac
    18781 ggctggtttc ttcctcacaa aaacataaac aatcttgtgc agcttctgct ttttctttaa
    18841 aggaaagctt gtttttcctc atttcatcac ttccttttca gacatacact gctcacgcag
    18901 atacaacaga atatggaagg tgaatgtgtt tgcttgtaca aacagccgag ggtaaaagct
    18961 gtttttgaag aaattccggc caccatgcgg tgtaacgaaa gaaaagattg cggttttttt
    19021 gcgcttctca caagaatgat gatgataaaa tatgacatat atagaataat gaagggaggg
    19081 attttcaaac gtgacaagtg tcatatcttc ttcttccgtt ggagaaaaga ttaatgaatg
    19141 gtatatgtac atacgccgat tcagcatacc ggatgcggaa tatttacgaa gagaaatcaa
    19201 acaagagcta gatcaaatgg aagaagacca ggatcttcat ttgtattatt cactgatgga
    19261 attccggcac aatctgatgc ttgagtatct tgaaccgtta gaaaacatgc ggatagagga
    19321 acagccgcga ctgtccgatt tgctgcttga aatcgataaa aaacaggctc gtttaaccgg
    19381 actgcttgaa tactacttta atttcttcag aggtatgtac gaactggacc gccgggaata
    19441 tatattagcc attcaatttt ttaaaaaagc agagagcaaa ctgacttttg ttaaagataa
    19501 aattgataaa gctgagttct ttttcaaaat gtcagaagtt tattactata tgaagcaaac
    19561 ttatgtgtcc atggactatg cacgtcaagc ctttgaaata tacaatgaac aaactacata
    19621 tgatatcaga atgattcaat gtcaatccct gtttggagct aactttttgg atctgaaaca
    19681 gtatgataaa gcaattgctc atttccaaaa agcttataca cttgctgagg cggcacagca
    19741 gccgcagcta atgggaagga cgctttataa tattgcactt tgcaagcaaa accaacacag
    19801 tcttgaatca gcgatagagt atgtaaaaaa atctattcat gtatttgaag aatcgaaaat
    19861 gcttccttca ctgccacaag cttttttcct aattacacaa atttatttta aattaggtaa
    19921 gattgataac gcttgtgaat atcataaaaa aggaagagaa tattcaatag ctgccggaga
    19981 cactgtgtac ttaatggagt ttgaattttt ggaatcttta tacttgtctg gacctgatga
    20041 agaggcaata gaaaaatgtt ttgttttcct tgaaagtaaa atgatgtatg ctgatattga
    20101 agactttgca ctcgatgttg ctaagtatta tcatcagcag gaaaattaca aaaaagcatc
    20161 tacttatttt ttaaaggttg aagaagcaag acagcacatt caaggggggg tgaatttata
    20221 tgaaatggaa gtataaatta ttactcgctt gtttagcggt gagtgctgta tttgtcacag
    20281 tagaagtatc aaattcatct acagaacatt ttgatgttgc acaacgtgct atgatctaag
    20341 accgccttta tcggcggttt ttttcgtccc ctctttccat cttgaataag atgtttgcaa
    20401 agcatgggaa caaaaaacat ccagacaaag tctggatgtt tctcttattt cacaaaccca
    20461 agcagcattt cacgaatgat tttgctggct gtgtttgccg tttgctctga gtggtcgtaa
    20521 atcggagcta cttctactaa atctgcgccc ttcacgttta cttctgagcg cgcgatttca
    20581 tggaccgatg caagcagttc tttagacgtg atgccgcctg cgtcaaccgt tcctgttccc
    20641 ggtgcgtgag cagggtctaa tacgtcaatg tcgattgtga catataccgg acggcctgcc
    20701 agcttcggaa gaaccttttt cagcggctca agcacttcaa acttagagat gtgcatgccg
    20761 ttttcctttg cccattcgaa ctcttctttc ataccggaac ggattccgaa tgaatacaca
    20821 ttttccgggc cgattaattc cgccgcttta cggatcggcg ttgagtgaga aagcggttct
    20881 ccctcataat cgacgcgaag atccgtatgt gcatcaaaat gaataatcgc caggtcagga
    20941 aatttcttgt acattgcttt catgacaggc catgacacga gatgctcccc gcccataccc
    21001 atcgggaatt ttcctttttc taaaatgctg tccacatatt cttcaatcat atcaagactt
    21061 ttttgcgggt ttccgaatgg cagcggaatg tcgccggcgt caaagaagtt caggtccgcc
    21121 agatcacggt ccagatacgg gctgtattct tcaaggccga ttgacacctc gcggattctt
    21181 cccgggccga agcgtgatcc cggacgatag ctcaccgtcc agtccatcgg catgccgtaa
    21241 aggatggcgt ccgcctcttc ccactctgga cggctcgcga taaatacttt tcctgaataa
    21301 gcttcatcaa atctcatcta taaaaccctc gctttcctgt aaaaaagcgc aagattcgct
    21361 cctgcgccat acattcatta tttaatcagg tcactcacaa atttcggcag aacaaacgcc
    21421 gctttatgaa gatcttttgt gtaatatttc gtgtcaatgt caaagaaacg gctgtcttcc
    21481 actgcaagcg gatcatattt tttcgaaccg attgtaaatg tccacaaacc gcttgggtat
    21541 gtcggaatgt tcgccgtata cagcttcgta atcgggaaga tttccttcac gtcacgctgt
    21601 acatttgtga tca
//
