LOCUS       NZ_CP048882            21059 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Streptomyces bathyalis strain ASO4wet chromosome, complete genome.
ACCESSION   NZ_CP048882
VERSION     NZ_CP048882.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces bathyalis
  ORGANISM  Streptomyces bathyalis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7377472)
  AUTHORS   Risdian,C., Landwehr,W., Rohde,M., Schumann,P., Hahnke,R.L.,
            Sproer,C., Bunk,B., Kampfer,P., Schupp,P.J. and Wink,J.
  TITLE     Streptomyces bathyalis sp. nov., an actinobacterium isolated from
            the sponge in a deep sea
  JOURNAL   Antonie Van Leeuwenhoek 114 (4), 425-435 (2021)
   PUBMED   33595745
REFERENCE   2  (bases 1 to 7377472)
  AUTHORS   Risdian,C., Landwehr,W., Schupp,P. and Wink,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2020) Microbial Strain Collection, Helmholtz
            Centre for Infection Research, Inhoffenstrasse 7, Braunschweig,
            Niedersachsen 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-FEB-2019
            Assembly Method                   :: HGAP v. v3
            Assembly Name :: Streptomyces_DSM106605_HGAP3_1SC_10M
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 117.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015910445.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 04:35:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,467
            CDSs (total)                      :: 6,387
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 111
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 37 of 111
            Pseudo Genes (incomplete)         :: 90 of 111
            Pseudo Genes (internal stop)      :: 12 of 111
            Pseudo Genes (multiple problems)  :: 25 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:44:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4100025
            Orig. end                         :: 4121084
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048882.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MISG, Helmholtz Centre for
            Infection Research, Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="16"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(155..4279)
                     /gene="hrpA"
                     /locus_tag="G4Z16_RS17835"
                     /old_locus_tag="G4Z16_17810"
     CDS             complement(155..4279)
                     /EC_number="3.6.4.13"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003724 - RNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="hrpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007383078.1"
                     /locus_tag="G4Z16_RS17835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17810"
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="WP_197351747.1"
                     /transl_table=11
                     /translation="MPTSTSPSPSFDALRERLPELMLRDQQRLGRRLDGARKIRKPEAR
                     DSVLAEISAAMDDSELKVASRRESRPAITYPEQLPVSRKKDEILEAIRDHQVVIVAGET
                     GSGKTTQIPKICMELGRGIHGVIGHTQPRRLAARTVAERVAHELKSPLGEAVGWKVRFT
                     DQVGENTLVKLMTDGILLAEIQQDRELRQYDTIIIDEAHERSLNIDFLLGYLAQLLPRR
                     PELKVVITSATIDPERFSRHFGDAPIVEVSGRTYPVEVRYRPLLEEGAPESDGQGGATG
                     EKDRDQTTAICDAVDELQSEGPGDILVFLSGEREIRDTADALEKRIAGKGRKAGAGAGG
                     DTEILPLYARLSHAEQHRVFQSHQNRRVVLATNVAETSLTVPGIKYVVDPGTARISRYS
                     HRTKVQRLPIEPVSQASANQRKGRCGRTSDGICVRLYSEEDFLSRPEFTDAEILRTNLA
                     SVILQMTAAGLGDIEKFPFIDAPDHRSIKAGVQLLEELHAFSASPASRTSKGGNRLTGT
                     GRKLAQLPVDPRLARMVLEAERNGCVREVIVIVAALSIQDPRERPSDKQQQADQQHARF
                     REEGSDFLALLNLWRYVRERQKELSSSAFRRMCKAEFLNYLRIREWQDIYAQLRQVAKA
                     MDILPASSSQEASADAVHQSLLAGLLSHIGLKDTDKNEYLGARSAKFAVFPGSSLFKKQ
                     PRWLMSAELVETSRLWARVNAKVEPEWIEPLAEHLVKRTYSEPHWEQKQAAVMAYERVT
                     LYGVPLVAQRKVNYGRIDPETCRDLFIRHALVEGDWRTHHRFFHDNRKLLDEVEELEHR
                     ARRRDILVDDETLYDFYDERVPEHVVSGAHFDSWWKKQRREDPDLLNFEKSMLINEQAE
                     EISRSDYPDVWQQGQLTLRVTYQFEPGTDADGVTVHVPLQVLNQITPAGFDWQIPGLRE
                     SLVTELIRSLPKAVRRHYVPAPDFAARFLRVATPGQEPLTATLARELRGMVGVPFEAGD
                     FDPEKVPDHLKVTFRVTDERRRTLAESKDLEELQHQLRDKTQAAIARAFESSARAQRKE
                     AGERDTNSPSAQEPAPGPGSGEAAPALSSRSGLTEWTIGSLPRVFETRSRASGGKGPVG
                     AQPVKAYPALVDDGDSVSVHLFDTEAEQQQAMWRGTRRLILLNIPSDPAKFAASKLSNP
                     QKLALSRSPHGSVQALFEDCVTAAADRLITGHGGPAWDEEAFRKLFDAVRTDLVDTTLK
                     TVKQVQEVLAAWHSCETRLRGITSPALADSADDVRRQLADLVSPGFVTRHGAARLPDLL
                     RYLVAADRRLQQMPNNAERDRTRMAKVKEMQDEYLWLLEQFPRGRPVPQAALEIRWMIE
                     ELRVSYFAHALGTAYSVSDKRIMKAVDAAAP"
     misc_feature    complement(4275..4293)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            4600..5601
                     /locus_tag="G4Z16_RS17840"
                     /old_locus_tag="G4Z16_17815"
     CDS             4600..5601
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009193067.1"
                     /locus_tag="G4Z16_RS17840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17815"
                     /product="ABC transporter permease"
                     /protein_id="WP_246531314.1"
                     /transl_table=11
                     /translation="MGARSGWRTFRHTPFFPATVLALIVAAAAGLFASSYIYAMADPTP
                     RTIPAAVVERPAGERSARAFIDGLEKALGSSLKVHRYRTFAQAEDAVDDQKVFAVLRAD
                     ARDRVELNLASAAGASVAEVLQQTAPKVGKEVGVSVTVKDLKPLGRGDPRGLTIFYMTL
                     AADVIGFIGAIQLTLNVPELTPVARISFITAYALIGGFIIAAMVGWFLQAVHLPFVHSW
                     TILALTMFTSGMVFVMFNALIGRWAMIPTWLLMVLLGNPSSGGAVSWPLLPSALGAVGR
                     WLPPGASVNAQHTAVYFAGHEHALPYLVLAAWALAGMGVFLALDHRRQAAER"
     gene            5723..5932
                     /locus_tag="G4Z16_RS17845"
                     /old_locus_tag="G4Z16_17820"
     CDS             5723..5932
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G4Z16_RS17845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="G4Z16_17820"
                     /product="hypothetical protein"
                     /protein_id="WP_197351749.1"
                     /transl_table=11
                     /translation="MTMEPLDLVNSLSAVVSAVAAIVSAVVSLKSSNGRQRPAEANGED
                     ELPPWMIVPSGKLRASEALCPVPA"
     gene            complement(6051..7106)
                     /gene="sph"
                     /locus_tag="G4Z16_RS17850"
                     /old_locus_tag="G4Z16_17825"
     CDS             complement(6051..7106)
                     /EC_number="3.1.4.12"
                     /GO_function="GO:0004767 - sphingomyelin phosphodiesterase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="sph"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848368.1"
                     /locus_tag="G4Z16_RS17850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17825"
                     /product="sphingomyelin phosphodiesterase"
                     /protein_id="WP_197351750.1"
                     /transl_table=11
                     /translation="MPPSASADPTPAPPPRRPGRLRGLKGLAAAGALAATALVATGSSA
                     TAAPEATARPGEKAAAEAPGLKVLSYNTFLFNKLIYPNWGQDHRGDAIPDADFFQGNDV
                     VVLQEAFENSVSDKLQEKAAGQYPHQTPVLGRSKSGWDATGGSWSDIAPEDGGVTILSK
                     WPIVHKEQFVYDHGCGADYLSNKGFVYAVLDVGGTKVHVVGTHVQAGDSACGDGEAKEI
                     RAEQFRAIDSFLDEKKIPADEQVMVAGDFNTDSRGDEYASMLANADLAPADARTGHPYS
                     SDHQTNSIAKGRDPDGGRSDLDYVLHRNGHVRPAGWQNEVIKEECAPWETSEGTFTNLS
                     DHYPVIGGPAS"
     gene            7421..8893
                     /locus_tag="G4Z16_RS17855"
                     /old_locus_tag="G4Z16_17830"
     CDS             7421..8893
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018840504.1"
                     /locus_tag="G4Z16_RS17855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17830"
                     /product="FG-GAP and VCBS repeat-containing protein"
                     /protein_id="WP_197351751.1"
                     /transl_table=11
                     /translation="MRVRTLCAVVAGLAVALTGGAASATGQAETAGGKAAMKASVQEDF
                     NGDGYQDVATAAPGATIAGQARAGYVVVTYGSASGLHAGNSTYINQNTAGVPGTAEAED
                     YFGAKLIARDLDGDGLTDLAVRSSGEQVTNGYGSVTVLWGRTGAISGQDSATIAAPATE
                     YWQVGANLTAGDFDGDGSTDLFMQYGDDWEFRSVLSGPFTRDGEAADEQQIDMFTTDND
                     IYVTTAGDVTGDGIDDLATFYVYQNHAEGGRFWPGTASGLSTDAKQLSSAAAAVVGDFD
                     KDGKGDLATRTVPNGITEDLPYDAGTVKIYYGTADGPSTTRTRTITQNTTGVPGSSEKG
                     DQFGARLDASDVNGDGYADLAAGVPFEAIGTKKAAGGVVLLKGRSGGLSGTGAQAFHQD
                     TSGIPGVAEAGDRFGGAVRLLDVTKDAKAELAVSAPEENKTGAVWSLRGTSSGLTATGS
                     LAFNPVDLGTPATGAGFGYAFSNEPGTFLYAP"
     misc_feature    complement(7430..7448)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.81"
                     /tool="antismash"
     gene            complement(9068..9943)
                     /locus_tag="G4Z16_RS17860"
                     /old_locus_tag="G4Z16_17835"
     CDS             complement(9068..9943)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069177.1"
                     /locus_tag="G4Z16_RS17860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17835"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_197351752.1"
                     /transl_table=11
                     /translation="MATSHTGTTFATVPNQSTYQSRVADYWNAEENPVNLELGKVDDLY
                     HHHYGVGEADRSVLDEPDPDKRNERITHELHRLEHAQAELLASHLGELSPADRVFDAGC
                     GRGGGSVVANLRYGCHADGVTLSTKQADFANEQARTRGIGGKVRYHHRNMLDTGFDSGA
                     YAASWNNESTMYVELDLLFAEHARLLRRGGRYVVITGCYNDTYGQASREVSLINAHYIC
                     DIHPRSAYFRAMARNRLVPVHVQDLTAATIPYWELRREADHLATGIEDTFLNAYRNGSF
                     QYLLIAADRV"
     gene            complement(10001..11059)
                     /locus_tag="G4Z16_RS17865"
                     /old_locus_tag="G4Z16_17840"
     CDS             complement(10001..11059)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981047.1"
                     /locus_tag="G4Z16_RS17865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17840"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_197351753.1"
                     /sec_met_domain="T1TS (E-value: 5.5e-51, bitscore: 172.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSTNVTAGFSPPRAPGPPGAMPSRRLGAVPGLTYRPAAPADPE
                     KVAEIDRRLKDWARELDLFPAEWTGDFTQFRFGRAVVLQHPGAADLERLTVAGKLLLAE
                     NMVDSCYCEEDEGRGGAHRGLGGRLVVAQSALDPFHGPPEQEEEWRRGVRADGPLRSYH
                     CAVKDYAAIATPSQTDRFVHDIARLHLGYLAEASWAETRHVPQIWEYLVMRQFNNFRPC
                     LSIVDAVDGYELPEPLYARPEIQRITALACNATTIVNDLYSFTKELASDPAHLNLPQVV
                     AANDKRGLKAAYLKSVEIHNQVMEAFETESALASATSPLIERYARSLAAWVSGNHEWHA
                     TNTDRYSLPNYW"
     misc_feature    complement(11333..11347)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.58"
                     /tool="antismash"
     gene            11735..13996
                     /locus_tag="G4Z16_RS17870"
                     /old_locus_tag="G4Z16_17845"
     CDS             11735..13996
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964556.1"
                     /locus_tag="G4Z16_RS17870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17845"
                     /product="hypothetical protein"
                     /protein_id="WP_246530921.1"
                     /transl_table=11
                     /translation="MAASGAVRSEFLRRAHPAAWRHARWVRPVRVLACVVAVVCVAALV
                     GAATLRATVLERGYYQGVLDDERAYDRLYDKVLVDPRSHPVTKSLLSRLPVPESVVTAN
                     LKTVLPPATVRQLTDEQIAALVGYFRGDSDTLGVSVNLRPVLANVGELAQVYLGDLASG
                     QRASPESDVSAALARLDKALDRIAEGRKPADLPKVELSDRAVDTVSSALLSGVPSKERA
                     SLRPQVEGALAVGDAGTALAAAGPHLPGSKAGSGEESRRDLLRMADGGRWNAVRDLKGA
                     GFETGALESARDATRFMQGPAQTLSVVVGGLAVVFLWVSGPPGRRTRRLRTVGWILAVG
                     GALPAALFWAVRRGADDLLWQAPATWPASLAGLVEDLERNALATFTTAGLSAAVVPFAA
                     GALLVTATYVRERHRALRRALVAMTRRTRTRLVGISSVALAASVVLGVVFAPSAAGGPE
                     RTYCNGSAEMCGLRYDEAAYLTTHNSMSSTADRFISPLQDGDIRTQLDDGARALLVDTH
                     LWERSEQVAERLKVSDFAPRMRGKVADLIDRTGPARPGPWLCHAVCRAGAVPLVDTLRE
                     IRTWMDQHPGEVVTLIVQSGITGDQTASAFRKAGLQDLLFTPDRDPKTPWPTLGDMVAD
                     NKRLVVFSEGSGGPAAWYRGFYRYGMETPYDFRDPRKMSCAPNRGGTGKRLFLLNHFIT
                     DAGGSRLDAGQVNAKDFVRDRARRCGAERGRPVNFVAVDFANVGDARGAVAAINAARTR
                     "
     misc_feature    complement(14192..14207)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    14193..14206
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.17"
                     /tool="antismash"
     gene            14216..14446
                     /locus_tag="G4Z16_RS17875"
                     /old_locus_tag="G4Z16_17850"
     CDS             14216..14446
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540960.1"
                     /locus_tag="G4Z16_RS17875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17850"
                     /product="hypothetical protein"
                     /protein_id="WP_197351754.1"
                     /transl_table=11
                     /translation="MDANAFPRDLLEAQTAWYTTYWRLANAASSHGTTEHRRRLQQLSR
                     RIADHPYWRTTAGTPEARMALKEIARTHARP"
     gene            complement(14547..14771)
                     /locus_tag="G4Z16_RS17880"
                     /old_locus_tag="G4Z16_17855"
     CDS             complement(14547..14771)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134358.1"
                     /locus_tag="G4Z16_RS17880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17855"
                     /product="hypothetical protein"
                     /protein_id="WP_197351755.1"
                     /transl_table=11
                     /translation="MDNVSCTQCDTDGLEPGFIEDSGEHSRGYARWIAGPLERGIFGGA
                     KRMGRQRWQIEAHRCPNCGHLELFVRQPA"
     misc_feature    14810..14825
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            complement(14849..15196)
                     /locus_tag="G4Z16_RS17885"
                     /old_locus_tag="G4Z16_17860"
     CDS             complement(14849..15196)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133238.1"
                     /locus_tag="G4Z16_RS17885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17860"
                     /product="VOC family protein"
                     /protein_id="WP_197351756.1"
                     /transl_table=11
                     /translation="MAVDLFAGIPVRHYSRAAAWYEQLLGTPPSFVPDDTEAVWELADH
                     RFLVIEVRPEHAGHAMHTVFVDDFDDRIAQISERGLEPVARETYDNGVRKAVFRDPDGN
                     EIGFGGGPAHL"
     tRNA            complement(15447..15520)
                     /anticodon=(pos:complement(4115509..4115511),aa:Phe,
                     seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="G4Z16_RS17890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="G4Z16_17865"
                     /product="tRNA-Phe"
     gene            complement(15447..15520)
                     /locus_tag="G4Z16_RS17890"
                     /old_locus_tag="G4Z16_17865"
     tRNA            complement(15584..15658)
                     /anticodon=(pos:complement(4115646..4115648),aa:Asp,
                     seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="G4Z16_RS17895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="G4Z16_17870"
                     /product="tRNA-Asp"
     gene            complement(15584..15658)
                     /locus_tag="G4Z16_RS17895"
                     /old_locus_tag="G4Z16_17870"
     tRNA            complement(15698..15770)
                     /anticodon=(pos:complement(4115759..4115761),aa:Glu,
                     seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="G4Z16_RS17900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="G4Z16_17875"
                     /product="tRNA-Glu"
     gene            complement(15698..15770)
                     /locus_tag="G4Z16_RS17900"
                     /old_locus_tag="G4Z16_17875"
     gene            complement(15855..17582)
                     /locus_tag="G4Z16_RS17905"
                     /old_locus_tag="G4Z16_17880"
     CDS             complement(15855..17582)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009189427.1"
                     /locus_tag="G4Z16_RS17905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17880"
                     /product="metallophosphoesterase"
                     /protein_id="WP_197351757.1"
                     /sec_met_domain="Metallophos_2 (E-value: 9.3e-10, bitscore:
                     37.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRDARKPRKPLSLPQWVRKPSVPNPVSLLRNRLFRPREAGGTRS
                     ARAARAASPYTLGLGPAPRPYVRALGLVATTLAGAWLGLLIVGGIDAPVGPMDTKMALR
                     PSLTGGTKVNVSPLGALELRSHAAPLRLDVDVDQLDQQRASALVDHPERLEGLESEITS
                     DVQKGTGDLALRSAVAVVVGAGVLGLAVYRRPRRALAASGLALALLAVSGAAAYATWNP
                     KSVLEPKFSGLLASAPSVVGNARSIVTDFDIYQRELARLVTNVTKLYEATSTLPAYEPD
                     PSTTRVLHVSDIHLNPAAWQIIKSLVEQYEIDAIIDTGDTMDHGTSAENGFLEPVTDLG
                     APYIWVRGNHDSAETQKAFEKLAKKKDSNVHVLDDGVPLNVAGLRLAGWGDPQFTPDRS
                     VKPQGDPRERKEGRRLALALRAQKAADTPVDIAVSHNPVLVKQTDGLVPLALAGHTHQR
                     TQERLPRHTRLMIEGSTGGGGLRAVEKEKPQKVSASVLYLGRDDGKLQAWDEITLGGLG
                     LTTAEVTRHLAEDKVDPRRSPSPSPGSSSPGSGPDSGSPGPTFSSPGPTPAASPANSP"
     gene            17673..18035
                     /locus_tag="G4Z16_RS17910"
                     /old_locus_tag="G4Z16_17885"
     CDS             17673..18035
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566395.1"
                     /locus_tag="G4Z16_RS17910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17885"
                     /product="metallopeptidase family protein"
                     /protein_id="WP_197354720.1"
                     /transl_table=11
                     /translation="MLEMTREDFEELVAEALDRIPPELTRLMDNVAVFVEDEPPAEDPE
                     LLGLYEGTPLTERGEWYAGVLPDRITVYRGPTLRMVGGEDGGRDGVVSEVEVTVVHEIA
                     HHFGIDDERLHELGYG"
     misc_feature    complement(17710..17724)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            18032..18607
                     /locus_tag="G4Z16_RS17915"
                     /old_locus_tag="G4Z16_17890"
     CDS             18032..18607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155047.1"
                     /locus_tag="G4Z16_RS17915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17890"
                     /product="CrcB family protein"
                     /protein_id="WP_197351758.1"
                     /transl_table=11
                     /translation="MSAEGGPDGDPAGGPRGPEDCGRPLSAGPPPWQEAVDPDVDLHVP
                     AQRAEAAGRHGLVVLAVIGAGGALGSLGRHALALWLPARGATGFPWGIFVVNLSGCALI
                     GVLMALVGEGGRDARAPALLRPFLGVGVLGGFTTFSTYAVDASHLLRAGPHAVPIAGAY
                     LGGTLLGALAAVWAGAAATRALLEVRGR"
     gene            18604..18978
                     /gene="crcB"
                     /locus_tag="G4Z16_RS17920"
                     /old_locus_tag="G4Z16_17895"
     CDS             18604..18978
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:1903425 - fluoride transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1903424 - fluoride transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003785.1"
                     /locus_tag="G4Z16_RS17920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17895"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_197351759.1"
                     /transl_table=11
                     /translation="MTWVLVAVGGMVGAPLRYLTDRAVQARRESVFPWGTFTVNAVGCL
                     MLGLLTGAVASGAAGSRIMAFLGTGLCGALTTYSTFSYETLRLAERGRGGLASANALLS
                     VLVGLGAVFAGLALARAVLA"
     gene            19048..19629
                     /locus_tag="G4Z16_RS17925"
                     /old_locus_tag="G4Z16_17900"
     CDS             19048..19629
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G4Z16_RS17925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="G4Z16_17900"
                     /product="hypothetical protein"
                     /protein_id="WP_197351760.1"
                     /transl_table=11
                     /translation="MRSSTSPFRSRAALYRPSPVRLTGVGERAARTVAGVLLLALLQGC
                     MTVHGDAGGGSDERRGGGSSSDAGAGGEVPEGGFSGSVLRHGEGARGGEDARRAHGSHR
                     ARHGRDADGKDGGGKRRAEDGGKRHRKNGSGKSGAGHDSSRDTPKAPDSPASPRPPRPK
                     PPSPPKPSVPKPTPTQSRPPSEAPTSPTSR"
     misc_feature    19847..19862
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.2"
                     /tool="antismash"
ORIGIN
        1 gatttgaacc cgcggcctcc accttgacag ggtggcgagc actccaaact gctccacagg
       61 accttgcgtg cacccggcga gcaggcgcga ccgagactct acagcagccc gccgagcggc
      121 gcgaactcac gttgtgcgac gggctcgtca ccgctcaggg cgccgccgca tccaccgcct
      181 tcatgatgcg tttgtccgag acggagtagg cggtgccgag cgcatgggcg aagtagctta
      241 cgcgcagctc ctcgatcatc cagcggatct ccagcgccgc ctgcggcacg ggccgtccgc
      301 gggggaactg ctccagcagc cagaggtatt cgtcctgcat ctccttgacc ttggccatcc
      361 gcgtgcggtc gcgttctgcg ttgttcggca tctgctggag gcggcggtcg gcggcgacga
      421 gatagcgcag caagtccggc agccgggccg cgccgtgccg cgtgacgaag ccggggctga
      481 ccaggtcggc gagctgacgg cggacgtcgt cggcggaatc cgcgagggca gggctcgtga
      541 tgccgcgcag acgcgtctcg cacgagtgcc aggcggccag cacttcctga acctgtttga
      601 ccgtcttgag cgtggtgtcg accaagtccg tacgtacggc gtcgaaaagc ttccggaaag
      661 cttcctcgtc ccaggccggt ccgccgtgcc ccgtgatgag gcggtcggcg gcggccgtga
      721 cgcagtcctc gaacagcgcc tgcacgctgc cgtgtgggga ccgggagagg gcgagcttct
      781 gggggttgga cagcttcgag gcggcgaact tggcagggtc ggaagggatg ttgagcaaga
      841 tcagccggcg cgtcccgcgc cacatggcct gctgctgctc ggcctcggtg tcgaagaggt
      901 ggacggacac ggagtcgccg tcgtccacca gcgccgggta ggccttcacg ggctgggcgc
      961 cgacggggcc cttcccgccc gacgcccggg aacgcgtctc gaagacgcgg ggaagggagc
     1021 cgatcgtcca ctcggtcagg cccgagcgtg aggacagggc cggtgccgct tcgcctgatc
     1081 cgggcccggg tgcgggctcc tgtgccgacg gcgagttcgt gtcccgctcc cccgcctcct
     1141 tacgctgcgc gcgtgcggac gactcgaatg cccgggcgat ggcggcctgc gtcttgtccc
     1201 gcagctggtg ctgcagttcc tccaggtcct tggactcggc cagggtgcgg cgccgctcgt
     1261 ccgtgacccg gaaggtgacc ttgaggtggt cggggacctt ctccgggtcg aagtcgccgg
     1321 cctcgaaagg cactccgacc attccccgca actcgcgcgc gagcgtggcg gtcagcggtt
     1381 cctgccccgg cgtcgcgacg cgcaggaacc gcgcggcgaa gtcgggcgcc gggacgtagt
     1441 gccgcctgac ggccttggga agcgagcgga tcagctcggt gacgaggctc tcgcgcaggc
     1501 cggggatctg ccagtcgaac ccggccggcg tgatctggtt gaggacctgc agcgggacgt
     1561 gcacggtcac gccgtcggcg tcagtgccgg gctcgaactg gtaggtgacg cgcagcgtga
     1621 gctgcccctg ctgccacacg tccgggtagt cgctgcggct gatctcctcc gcctgctcgt
     1681 tgatgagcat cgacttctcg aagttgagca ggtccgggtc ctcgcgacgc tgcttcttcc
     1741 accacgagtc gaagtgggcg ccggacacga cgtgttcggg gacgcgctcg tcgtagaagt
     1801 cgtacagcgt ctcgtcgtcg acgaggatgt cgcggcggcg cgcgcggtgc tccaactcct
     1861 ctacctcgtc gaggagtttg cgattgtcat ggaagaaacg gtggtgcgtg cgccagtcgc
     1921 cctcgaccag ggcgtgccgg atgaacaggt cccggcacgt ctccgggtcg atacgcccgt
     1981 agttgacctt gcgctgcgcc acgagcggta ccccgtagag cgtcacgcgc tcgtacgcca
     2041 tcacggcggc ctgcttctgc tcccagtgag gctcgctgta cgtgcgcttc accaggtgct
     2101 ccgcgagcgg ctcgatccat tccggctcga ccttggcgtt gacgcgggcc cacagccgcg
     2161 acgtctccac gagttcggcg gacatcagcc agcggggctg cttcttgaag agcgacgagc
     2221 cggggaagac ggcgaacttc gcgctgcggg cgcccagata ctcgttcttg tcggtgtcct
     2281 tgagcccgat gtgggagagg aggccggcca gcagggactg gtgcacggcg tcggccgacg
     2341 cctcctggga ggacgaggca ggaaggatgt ccatcgcctt ggccacctgg cgcagctggg
     2401 cgtagatgtc ctgccactcc cgtatgcgca ggtagttgag gaactccgcc ttgcacatgc
     2461 ggcggaacgc ggacgaggac agctccttct gccgctcgcg cacgtagcgc cacagattca
     2521 gcagggcgag gaagtcgctg ccctcctcgc ggaagcgcgc gtgctgctgg tcggcctgct
     2581 gctgcttgtc cgaggggcgc tcgcgagggt cctggatgga cagggccgcg acgatcacga
     2641 tcacctcgcg cacgcacccg ttccgctcgg cctccagcac catgcgcgcg agccgcgggt
     2701 cgacggggag ctgcgcgagc ttgcggcccg taccggtgag gcggttgccg cccttcgagg
     2761 tgcgggacgc gggggaggcg ctgaacgcgt gcagttcttc gaggagttgg acgccggcct
     2821 tgatgcttcg gtggtcgggc gcgtcgatga aggggaactt ctcgatgtcc ccgaggccgg
     2881 ccgcggtcat ctggaggatg acggaggcga ggttcgtgcg caggatctcg gcgtccgtga
     2941 actccggcct ggagaggaag tcctcctcgg agtagagccg gacgcagatc ccgtcggacg
     3001 tgcggccgca gcggcccttg cgctggttgg cgctggcctg gctgaccggc tcgatgggca
     3061 gccgctggac cttggtgcgg tggctgtagc gcgagatgcg ggcggtgccc gggtccacga
     3121 cgtatttgat gccggggacg gtgagggagg tctccgcgac gttcgtggcg aggacgacgc
     3181 ggcggttctg gtggctctgg aagacgcggt gctgctcggc gtgggagagg cgggcgtaga
     3241 gggggaggat ctcggtgtcg ccgccggctc ccgcgcccgc cttgcggccc ttgccggcga
     3301 tgcgtttctc cagtgcgtcc gcggtgtccc ggatctcacg ctcgccggag aggaagacca
     3361 ggatgtcgcc ggggccctcg gactgcagct cgtcgaccgc gtcgcagatc gccgtcgtct
     3421 ggtcgcggtc cttctccccg gtggcacctc cctggccgtc agactcaggg gcaccctctt
     3481 cgaggagggg cctgtagcgc acctccacgg ggtacgtacg cccgctgacc tcgacgatcg
     3541 gagcatcgcc gaagtgccgt gagaagcgct ccgggtcgat cgtcgcggag gtgatgacga
     3601 ccttcaactc cgggcgtctg ggcagaagtt gcgcgaggta gccgagcagg aagtcgatgt
     3661 tgaggctgcg ctcgtgcgcc tcgtcgatga tgatcgtgtc gtactgccgc agctcgcggt
     3721 cctgctggat ctcggcgagc aggatgccgt ccgtcatcag cttgaccagg gtgttctccc
     3781 ccacctggtc ggtgaagcgg accttccagc cgacggcttc gcccagcggt gacttcagct
     3841 cgtgggcgac gcgctcagcg accgtacggg ccgcgagccg gcgcggctgg gtgtggccga
     3901 tgacgccgtg gatgccgcgt cccagctcca tgcagatctt cgggatctgc gtcgtcttgc
     3961 ccgagccggt ctcacccgcg acgatcacga cctggtggtc ccgtatcgcc tcgaggatct
     4021 cgtccttctt gcggctgacc ggaagctgct ccggatacgt gatcgcgggc cgggactcgc
     4081 ggcgggatgc gaccttcagc tcggagtcgt ccatggccgc ggagatctcc gccagcaccg
     4141 agtcgcgcgc ctccggcttg cggatcttgc gtgcgccgtc gaggcgccgc cccagccgct
     4201 gctggtcgcg cagcatcagc tcgggcaggc gctcgcgcag agcgtcgaag gacggggagg
     4261 gggacgtgga tgtcggcata ccggatccag gatcgcactt caccgaatcc accggccaac
     4321 caattccccc cggcgcccca ggcggtctcc cggagccctc gccgaggggc cggtgagggc
     4381 accggtgggc gccgcacgcg gacacgggaa gcgaagcagc aaagcccgtg aacggtgcaa
     4441 atcggaccta gggtggcgcg catgagtgaa ccgcgcgagc cggagccgca cgatccgcgt
     4501 gatccgcagc cgccggacgg ctcgacggct ccggacggcg cggacgactc ccatgctccg
     4561 ccggggcggc acggtgcgcg gggcgtgcag cgcccgccga tgggcgcgcg ctccggatgg
     4621 cggaccttca ggcacacgcc gttcttcccc gcgaccgtgc tggcgctcat cgtcgccgcg
     4681 gcggccggcc tcttcgccag ctcctacatc tatgccatgg ccgaccccac gccccgcacc
     4741 atcccggcgg cggtcgtgga acgccccgcg ggtgaacgca gtgcccgcgc cttcatcgac
     4801 ggcctggaga aggcgctcgg ctcgtcgctc aaggtgcacc gctaccgcac attcgcccag
     4861 gccgaggatg ccgtcgacga ccagaaggtg ttcgcggtgc tgcgggcgga cgcccgggac
     4921 cgcgtcgagc tgaacctcgc gagcgccgcc ggcgcctcgg tggccgaggt gctgcagcag
     4981 accgcgccga aggtcgggaa agaggtgggc gtgagcgtga ccgtcaagga tctcaagccg
     5041 ctcggcaggg gcgacccgcg cggactgacg atcttctaca tgacgcttgc cgccgacgtc
     5101 atcggcttca tcggcgcgat ccagctcacc ctcaacgtcc cggaactcac cccggtcgcc
     5161 cggatctcct tcatcaccgc ctacgcgctg atcggcggct tcatcatcgc cgcgatggtg
     5221 ggctggttcc tgcaggccgt gcatctgccg ttcgtgcact cctggacgat cctcgcgctc
     5281 accatgttca cctcgggcat ggtcttcgtg atgttcaacg ccctcatcgg acgatgggcg
     5341 atgatcccca cctggctgct gatggtgctc ctcggcaatc cgtcctcggg cggtgcggtc
     5401 tcctggccgc tgctcccctc ggcgctgggc gcggtcggac gctggctccc cccgggggcg
     5461 tccgtcaacg cccagcacac ggccgtctac ttcgcgggcc acgagcacgc gctgccttat
     5521 ctggtgctcg ccgcgtgggc gctggcgggc atgggcgtct tcctcgcgct ggaccaccgg
     5581 cggcaggccg cggagcggtg acgcggggac gacaggaacg tttgcgtcac tgaggcccag
     5641 tcgtcgcaaa atcatctgtc gcaccggtcc gctgagctga catcgtgtca ccaggcaact
     5701 cactgcggac gaagggaggg cgatgacgat ggaaccactc gatctcgtca attcgctcag
     5761 tgccgtcgtc agcgccgtgg ccgccatcgt gagcgccgtc gtttcgctga aatcctcgaa
     5821 cggccggcag cggcccgcgg aagcgaacgg tgaggacgaa ctgccgccgt ggatgatcgt
     5881 gccgagcggc aagctgaggg cgtccgaagc cctgtgcccg gtcccggcct gagaccggcg
     5941 cgaagccggc gcagcacctg agacccgcct tcccggaccc cgcagaccga taccgatccg
     6001 acggaccccc ggcacactgg gccgggggtc cgtcgctgct catgggcgct ctatgaggcg
     6061 gggccgccga tcaccggata gtggtcggag agattcgtga acgtgccctc cgaggtctcc
     6121 cagggtgcgc actcctcctt gatgacctcg ttctgccagc cggcgggacg gacgtggccg
     6181 ttgcggtgca gcacgtagtc caggtcggac cggccgccgt cggggtccct tcccttggcg
     6241 atcgagttcg tctggtggtc cgaggagtag gggtgtccgg tgcgggcgtc ggcgggggcg
     6301 aggtcggcgt tggcgagcat ggacgcgtac tcgtcgcccc gcgagtcggt gttgaagtcg
     6361 cccgcgacca tgacctgttc gtccgcgggg atcttcttct cgtcgaggaa ggagtcgatc
     6421 gcgcggaact gctcggctcg tatctccttc gcctcgccgt ccccgcaggc cgagtcgccc
     6481 gcctggacgt gggtgccgac gacgtgcacc ttggtgccgc cgacgtcgag cacggcatac
     6541 acgaagccct tgttggagag gtagtcggcg ccgcatccgt ggtcgtagac gaactgttcc
     6601 ttgtggacga tcggccactt gctgaggatc gtgacgccgc cgtcctctgg tgcgatgtcc
     6661 gaccacgaac cgcccgtcgc gtcccagccg ctcttgctgc ggcccagcac gggtgtctgg
     6721 tgcgggtact ggcccgcggc cttctcctgg agcttgtcgg agacggagtt ctcgaacgcc
     6781 tcctggagca cgaccacgtc gttgccctgg aagaagtcgg cgtcggggat cgcatctccc
     6841 ctgtggtcct ggccccagtt gggatagatc agcttgttga agaggaacgt gttgtagctg
     6901 agcaccttga ggcccggggc ctcggccgcg gccttctcgc ccggccgggc ggtcgcttcg
     6961 ggtgccgccg tggccgatga accggtcgcc acgagcgctg tcgcggcgag ggcgccggcg
     7021 gcggcaagtc ccttgaggcc gcgcagtctt cccggtctgc ggggcggggg tgcgggcgtg
     7081 ggatcggcgg atgctgaggg tggcatgttc gtctcccgtg ggggggtggg gatacgtacg
     7141 actcatatcc aagcaagcaa gcttgattcc tgtcaccgtg ctcgcgcgcc aaagttgctt
     7201 cgacggggcc gagtcggagc ggagtcgggg cggaccaagg gccggtcagg ccggtcaggg
     7261 ccggacatgg ccggtcgggc cgcaactcgg aggcggatcg ggagggttgg aacgttgctc
     7321 ctgattgagg acgaaccagt tggcgcacaa cttttcgggc atggcgcgag tctcactcgt
     7381 accggcgcca ccaggcgcat cggggggact tggaggggca atgcgcgttc gcacactgtg
     7441 tgcagtcgtg gcagggctcg ccgtcgcgct cacaggagga gcggcatcgg cgaccggcca
     7501 ggcggagacc gccgggggga aggcggcgat gaaggcttcc gtacaggagg acttcaacgg
     7561 ggacggatat caggacgtgg ccaccgcggc ccccggggca acgatcgccg ggcaggccag
     7621 ggccggatat gtcgtcgtca cctacggctc cgcgtccggg ctccacgccg gcaacagcac
     7681 gtacatcaac cagaacaccg cgggcgtccc gggcacggcg gaggccgagg actacttcgg
     7741 cgccaagctg atcgcccgcg acctcgacgg cgacggcctc accgacctcg ccgtgcggtc
     7801 gtcgggcgaa caagtcacca acggctacgg ctcggtgacc gtcctctggg gccgtacggg
     7861 cgcgatcagc gggcaggact cggcgaccat cgcggccccg gccaccgagt actggcaggt
     7921 cggggccaac ctgaccgccg gcgacttcga cggcgacggc agcaccgacc tgttcatgca
     7981 gtacggcgac gactgggagt tccgctcggt gctctccggt ccgttcaccc gcgacggcga
     8041 ggcggcggac gagcagcaga tcgacatgtt caccaccgac aacgacatct acgtcaccac
     8101 cgcgggtgac gtgacgggcg acggcatcga cgacctggcc acgttctacg tctaccagaa
     8161 ccatgcagag ggcggccggt tctggcccgg caccgcttcc ggcctctcga cggacgcgaa
     8221 gcagctgagc tcagcggccg ccgcggtcgt cggcgacttc gacaaggacg gcaagggcga
     8281 cctggcgacc cgcacggtcc cgaacggcat cacggaagac cttccgtacg acgccggcac
     8341 cgtgaagatc tactacggca cggcggacgg cccgagcacc acccgcaccc ggacgatcac
     8401 gcagaacacc acgggcgtcc cgggcagcag cgagaagggc gaccagttcg gcgcccggct
     8461 cgacgcgagc gacgtcaacg gcgacggcta cgcggacctc gccgccggtg tccccttcga
     8521 agccatcggc acgaagaagg cagcgggcgg cgtcgtcctg ctgaagggac gctccggcgg
     8581 cctgagcggc accggcgcgc aggccttcca ccaggacacg tccgggatcc cgggcgtggc
     8641 cgaggccggt gaccgcttcg gcggggcggt gcgtctgctg gacgtcacga aggatgccaa
     8701 ggccgaactg gccgtctccg caccggagga gaacaagacg ggggcggtct ggtcgctgcg
     8761 cggcacgtcg agcggcctca ccgcgaccgg ctcgctcgcc ttcaacccgg tggacctcgg
     8821 caccccggcc accggcgcag gcttcggcta cgccttctcc aacgagccgg gcacgttcct
     8881 ctacgcgccg taagcggcgg ccgctccggc ggcgaagtgg acagcaccgg gtctgcctct
     8941 cggcgggccc ggtgccggtc tgttgagttc tccggtgctc aggatccgcg gggggatccg
     9001 cgtcccggcc ggagccaggg tgcgtccccg gcactgcggc tggggacgca cctcgggaac
     9061 gggagcgtca cacccggtcg gcggcgatca gcaggtactg gaaactgccg ttgcggtacg
     9121 cgttcaagaa ggtgtcctcg atgcccgtgg ccaggtgatc ggcctctcga cgcagttccc
     9181 agtacggaat cgtggcggcc gtcaggtcct ggacgtgtac ggggacgagc cggttgcggg
     9241 ccatggcgcg gaagtacgcc gagcggggat gaatgtcgca gatgtagtgg gcgttgatga
     9301 gggagacctc tcgggaagcc tgcccgtagg tgtcgttgta gcagccggtg atcaccacgt
     9361 agcgcccgcc gcgacgcagc agccgcgcgt gctccgcgaa cagcaggtcc agctcgacgt
     9421 acatggtgga ctcgttgttc caggacgccg cgtacgcacc cgagtcgaac ccggtgtcga
     9481 gcatgttgcg gtggtggtag cggaccttgc cgccgatgcc gcgcgtacgt gcctgctcgt
     9541 tggcgaagtc ggcctgcttg gtggagagcg tgaccccgtc ggcgtggcag ccgtaccgca
     9601 ggttcgccac cacgctgcct cccccacgtc cgcagccggc gtcgaagacg cggtcggcgg
     9661 gggagagttc accgagatgg gaggcgagca gctcggcctg ggcgtgttcc agccggtgca
     9721 gttcgtgggt gatccgctcg ttccgtttgt cggggtcggg ctcgtccagc accgaccggt
     9781 ccgcctcccc cacgccgtag tgatggtggt agaggtcgtc gacctttccg agttcgaggt
     9841 tgaccgggtt ctcttcggcg ttccagtagt ccgcgacacg ggactggtac gtggactgat
     9901 tcggcaccgt cgcgaaggtg gtgccggtgt gagaggtggc caacgatggc tccttgccgt
     9961 agtgcgtaga agtgcgtccg gtcggtcaag tgggctctga tcaccagtag ttgggcaggc
    10021 tgtatcggtc ggtgttggtg gcgtgccatt cgtggttgcc ggacacccag gccgccaggc
    10081 tgcgggcgta cctctcgatg aggggcgacg tcgcggaggc cagcgcggac tccgtctcga
    10141 acgcctccat cacctggttg tggatctcga cactcttcag ataggcggcc ttgagaccgc
    10201 gtttgtcgtt cgctgcgacc acctggggca ggttcaggtg cgccgggtcg ctcgccagct
    10261 ccttggtgaa ggagtacaga tcgttgacga tcgtcgtcgc gttgcaggcg agggccgtga
    10321 tccgctggat ctcgggccgg gcgtagagcg gttcgggcag ttcgtagccg tcgacggcat
    10381 cgacgatgga caggcaagga cggaagttgt tgaactgccg catcaccaag tactcccaga
    10441 tctgcggaac atggcgggtc tccgcccagg aggcctcggc cagatagccc aggtgcagcc
    10501 tggcgatgtc gtgcacgaac cggtcggtct ggctcggtgt ggcgatggcc gcgtagtcct
    10561 tcacggcaca gtggtacgag cgcagcggtc cgtcggcccg cactccccgg cgccactcct
    10621 cctcctgttc gggcgggccg tggaacgggt cgagggccga ctgggccacg acgagccggc
    10681 cgcccaggcc gcggtgcgcg ccgcccctgc cttcgtcctc ctcgcagtag cagctgtcga
    10741 ccatgttctc ggccagcagc aacttgccgg cgacggtgag gcgttcgaga tccgccgccc
    10801 cgggatgctg gaggaccacg gcccggccga accggaactg tgtgaagtcc cccgtccatt
    10861 ccgctgggaa caggtccagc tctcgtgccc agtccttcag ccgccggtcg atctccgcca
    10921 ccttctccgg gtcggccggt gcggcgggcc tgtacgtcag tccggggacg gctcccagcc
    10981 gccggctcgg catggcaccg gggggtccgg gagcgcgggg cggtgagaac ccggcggtga
    11041 cgttggtgga cgtgctcatg gtgcgtactc cacacggtcg gtccgcagcc cggccgagct
    11101 ggacgttctc caggactccg gctgcgtcgg tacggggaat ggcaggcgag tggtgatcgg
    11161 ccgcgcctct cggggatgcc ggcccggcaa gggctgcacc cggggttcgg ttctcgcgga
    11221 gttcggtctc gtggtcgtcg tcagttgggg cgcggcgtgt gggccgaggg ccgtggcacg
    11281 ttgatcgagg acggttcggg cggatcgtcg aggggcgaac ccgggcgcgc agaatgatct
    11341 aaacaagcga gaagagcagg ccggtagggc gtgacggggt ggtcgcacgc gcggagcgca
    11401 taaaccggcg tgacgagtca gacggcgcac gctgcccccc cgccgcacgc cgtctcggtg
    11461 gcacccgtgg cacgcggcga agggggcacg gttctgccga ggccgccccc ggtctgccga
    11521 ggccgtgccg tcttcctgca cctgtgtggc cgcgcccgcc accttccccc gtaccgctgt
    11581 cgagcttccc cgtaccgctg tcgagcttcc ccgtaccgct gtcgagtggg aatcggcatg
    11641 ggggcgtccg gattcgggaa cgcagccagg ccgggcccct gcaccacggg gcgctcgcga
    11701 cccggaccgg acccggagag ctggagggcg gacgatggcc gcgtctggcg ccgtgcgcag
    11761 cgagttcctg cgtcgtgctc accccgcggc gtggcggcac gcgcgctggg tgaggcccgt
    11821 acgggtgctg gcatgcgtgg tggcagtcgt gtgcgtcgcg gccctcgtcg gtgctgcgac
    11881 gctgcgcgcc acggtgctgg agcgcggtta ctaccagggc gtgctggacg acgagcgtgc
    11941 gtacgaccgg ctgtacgaca aggtcctcgt ggaccctcgc tcgcaccccg tcaccaagag
    12001 cctgctgtcc cggctgcccg tcccggaatc cgtggtgacg gccaacctga agaccgtgct
    12061 gcccccggcc acggtccggc agctgacgga cgagcagatc gccgccctgg tcggctactt
    12121 ccgtggcgac tccgacaccc tgggtgtgtc ggtgaacctg cgaccggtcc tcgcgaacgt
    12181 cggcgagctc gcgcaggtgt acctgggcga tctggcctcc gggcaacgag cctcgccgga
    12241 gtcggacgtg tcggcagcgc tcgcccgcct ggacaaggcc ctcgacagga tcgcggaggg
    12301 ccgcaaaccg gccgacctgc ccaaggtgga gctcagcgac cgcgcggtgg acacggtgag
    12361 ttcggccttg ctctccggcg tgccttcgaa ggagcgtgcc tcgctgcgac cgcaggtcga
    12421 gggggcgctc gcggtgggtg acgcgggcac ggccctggcg gccgccgggc cgcatctgcc
    12481 cggcagcaag gccggcagcg gggaggagag ccggagggac ctgctccgca tggccgacgg
    12541 cggccgctgg aacgccgtac gggacctgaa aggcgcgggc ttcgagacgg gcgccctgga
    12601 gtcggcacgc gacgccaccc gcttcatgca gggtccggcg cagacgctgt ccgtcgtcgt
    12661 cggaggtctc gccgtcgtct tcctctgggt gtccggacct ccggggcggc ggacacgccg
    12721 gctgcgtacc gtcggctgga tcctcgccgt gggcggcgcc ctgccggcgg ctctgttctg
    12781 ggcggtgcgc cggggtgccg acgacctgct ctggcaggct cccgcgacgt ggccggcgtc
    12841 gctggccggt ctggtggagg acctggagcg caacgccctc gccaccttca ccaccgcggg
    12901 actgtcggcg gccgtcgtgc cgttcgccgc cggcgcgctg ctggtgaccg cgacctacgt
    12961 acgggagcgc caccgggccc tgcgccgtgc cctggtcgcg atgacccggc gtacgcgcac
    13021 acgtctggtg ggcatctcct cggtcgccct ggcggcttcg gtcgtgctcg gcgtcgtgtt
    13081 cgcccccagc gcggcaggcg gcccggagag gacgtactgc aacggatcgg ccgagatgtg
    13141 cggcctccgc tacgacgagg ccgcctatct gacgacgcac aattcgatgt cctcgaccgc
    13201 cgaccggttc atcagccctc tccaggacgg cgacatcagg acccagctgg acgacggcgc
    13261 ccgcgcgctg ctcgtcgaca cccacctctg ggaacgctcc gaacaggtcg ccgagcggct
    13321 gaaggtgtcc gacttcgcac cccgcatgcg ggggaaggtc gcggatctca tcgacaggac
    13381 cggccccgcc cggcccggtc catggctgtg ccacgcggtc tgccgcgccg gcgcggttcc
    13441 gctcgtcgac acgttgcgtg agatccgcac atggatggac cagcacccgg gggaggtggt
    13501 cacgctgatc gtccagagcg gcatcaccgg cgatcagacg gcctccgcgt tccgcaaggc
    13561 gggtctgcag gacctgctgt tcaccccgga ccgcgacccg aagaccccgt ggccgacgct
    13621 gggcgacatg gtcgccgaca acaagcgtct ggtggtcttc tcggagggtt cgggagggcc
    13681 cgccgcctgg tatcgcggct tctaccggta cggaatggag accccgtacg acttccgtga
    13741 tccccggaag atgagctgcg cacccaaccg cggtggtacc ggcaagcggc tcttcctgct
    13801 caaccacttc atcacggacg cgggcggcag ccgcctcgac gccggccagg tcaacgcgaa
    13861 ggacttcgtg cgggaccgcg cccgccgctg cggggccgaa cgtggcaggc ccgtgaactt
    13921 cgtcgccgtc gacttcgcca atgtcggcga cgcccgcgga gcggtggccg ccatcaacgc
    13981 cgcacgcacc cgctgaggtc cccgggggga gtcagggaac tgggagggcc cggaactggg
    14041 agaacccgga actggggcgc gcgccctgaa cagggggcgc ccgtctcacc gacgtacggc
    14101 cgtcgggtcc ccgtcgtcaa gccggcggga atccgacgca gttcggtggg gacccgacgc
    14161 gaaaacgcgg cgtgcctggt tgccccagaa atcgaacata cgatctactc ggggtatgga
    14221 tgccaacgcc ttccctcgcg atcttctgga ggcccagacg gcctggtaca ccacgtactg
    14281 gcggctcgcg aacgccgcgt ccagccacgg cacgaccgaa cacaggcggc gcctgcagca
    14341 gctgtcccgg cgcatcgccg accacccgta ctggcggacc accgccggta cgccagaggc
    14401 ccggatggcg ctcaaggaga ttgcccgcac ccatgcgcgg ccgtgatgct caccgcccgg
    14461 caggaaactc gtccgccatg cgcatcagtt gccggctgcg tacgggcgcg tcggggccgt
    14521 aaggaccgcc agaaccgcag ttgtcatcac gcaggttggc gtacgaagag ctccaagtgc
    14581 ccgcagttgg ggcagcggtg agcctcgatc tgccagcgct ggcggcccat gcgcttggcg
    14641 ccgccgaaaa tgccgcgctc cagcggaccg gcgatccatc gcgcgtaccc ccgggagtgt
    14701 tctccggaat cctcgatgaa gcccggctcg agaccgtcgg tgtcgcactg ggtgcagctc
    14761 acgttgtcca tcgagggagt ctagaagggc cgtaggcagt cccacggatg tcacccagca
    14821 gtctcatccc agcagtccca gcaccgcttc agaggtgggc cggcccgccg ccgaagccga
    14881 tctcgttgcc gtccgggtcg cggaagacgg ccttgcggac cccgttgtcg taggtctcac
    14941 gcgcgacggg ctccaggccc ctctccgaga tctgggcgat gcggtcgtcg aagtcgtcga
    15001 cgaagacggt gtgcatggca tgaccggcat gctcgggccg cacctcgatg accaggaacc
    15061 ggtggtcggc gagttcccat accgcctcgg tgtcgtcggg cacgaacgaa ggcggagtgc
    15121 cgaggagttg ctcgtaccag gccgctgccc gggagtagtg acggacgggg atgccggcga
    15181 agaggtccac tgccaccacg ccatgctagt tctcccggct caggcccagc cgcccagagt
    15241 gcaggtcaac tggcgcggac cgggaccggg gtcgacccgg cgaccttccg cctggacgcc
    15301 ggttgcgtcg tctcgtgggc cttcagctga tcgactgcgc acgactgtta ccggttcggc
    15361 gagcggccga tgtcagcagg tgatgtcaca ggcagtaaaa cgccccctcc ggtgaccgga
    15421 gggggcgttc tcgctgttca ccgttgtggc tggggccggg gtcgaaccgg cgaccttccg
    15481 cttttcaggc ggacgctcgt accaactgag ctacccagcc cgggatccag gggcgaagcc
    15541 cccggtcggg atggccctca ggaggcgaag cgacccgagg gagcggtcct gacgggattt
    15601 gaacccgcgg cctccacctt gacagggtgg cgagcactcc aaactgctcc acaggaccaa
    15661 gcatcgcgcg agcaccagtc tcgcacaggg tggtgcgtgc ccccaacggg attcgaaccc
    15721 gtgctaccgc cttgaaaggg cggcgtcctg ggccactaga cgatgagggc tgatggccca
    15781 cctgagcgct tcgctgagtc agcgcgtcgg ggacgtgaga agcatatggg atagcggagc
    15841 gttcgccaaa acggttacgg ggagttcgcc ggggacgccg ccggcgtggg cccgggggag
    15901 ctgaacgtgg ggccgggcga acccgagtcc ggaccggagc ccggcgagct ggatcccggt
    15961 gagggcgagg gcgagcgccg ggggtccacc ttgtcctccg cgaggtggcg ggtgacctcc
    16021 gcggtggtca ggcccagccc gccgagggtg atctcgtccc aggcctgcag cttgccgtcg
    16081 tcccggccca ggtagaggac ggaggcggag accttctgcg gtttctcctt ctccaccgcg
    16141 cgcaggccgc cgccgcccgt cgagccctcg atcatcagcc gggtgtgccg cggcagccgc
    16201 tcctgggtgc gctggtgggt gtgtccggcg agagcgagcg gcacgagacc gtcggtctgc
    16261 ttgaccagga cggggttgtg ggagacggcg atgtcgaccg gagtgtccgc ggccttctgg
    16321 gcgcgcagcg ccagggccag gcgccgtccc tccttgcgtt cgcgcgggtc gccctgcggc
    16381 ttgacggaac ggtccggcgt gaactgcggg tcgccccagc cggcgaggcg cagcccggcg
    16441 acgttgagcg gcacaccgtc gtcgaggacg tggacgttgc tgtccttctt cttcgcgagc
    16501 ttctcgaacg ccttctgcgt ctcggccgag tcgtggttgc cgcgcaccca gatgtacggg
    16561 gcgcccaggt ccgtcacggg ttcgaggaag ccgttctcgg cggaggtgcc gtggtccatc
    16621 gtgtcgcccg tgtcgatgat cgcgtcgatc tcgtactgct cgacgagcga cttgatgatc
    16681 tgccaggcgg ccgggttgag gtggatgtcc gagacgtgga ggacgcgggt cgtggagggg
    16741 tccggctcgt aggcggggag ggtggaggtc gcctcgtaga gcttggtcac attggtgacg
    16801 agacgcgcca actcccgctg gtagatgtcg aagtcggtga cgatgctgcg cgcgttgccg
    16861 acgacggagg gcgcgctggc cagcagcccg gagaacttcg gttcgagcac ggacttcggg
    16921 ttccacgtcg cgtaggccgc cgccccggag accgccagca gcgcgagcgc gagaccgctc
    16981 gccgcgaggg cacggcgggg acgccggtaa acggcgagcc ccagcacccc ggccccgacg
    17041 accacggcga cggcggagcg cagcgcgagg tcacccgtgc ccttctgcac gtcggaggtg
    17101 atctcgctct ccagcccttc gagccgttcc ggatggtcga cgagggcgga ggcccgctgc
    17161 tggtccagct ggtcgacatc gacgtcgagg cggagcggag ccgcgtggct gcgcagctcc
    17221 agggcgccga gcggcgagac gttgaccttg gtgccgcccg tgagggaggg ccgcagcgcc
    17281 atcttcgtgt ccatggggcc cacgggcgcg tcgatgccgc cgacgatgag cagtcccagc
    17341 caggcgccgg cgagggtggt cgcgacgagt ccgagggcac gtacgtacgg gcgcggggcc
    17401 ggtccgaggc cgagcgtgta cggggacgcg gcacgtgccg cgcgggcgct ccgggtgccg
    17461 ccggcctccc gagggcggaa gaggcgatta cgcaggaggg acacggggtt cgggacggac
    17521 ggtttgcgta cccattgcgg cagagagagc ggtttacggg gcttcctggc atcgcggccc
    17581 atgaggcccc ctatgcccgt cgggcagcgc acctatgcga gctgccggta ccggccgtgc
    17641 acggcggagc tgcggtggcc gacaatggcc gggtgctgga gatgacgcgc gaggacttcg
    17701 aggagctggt ggccgaggcg ctcgaccgca ttccgcccga gctgacgcgg ctgatggaca
    17761 acgtcgcggt cttcgtcgag gacgagccac cggcggagga cccggagctg ctcggcctct
    17821 acgagggcac gccgctgacg gagcggggcg agtggtacgc gggcgtgctg ccggaccgga
    17881 tcacggtcta caggggcccg acgctgcgca tggtgggcgg tgaggacggc ggccgtgacg
    17941 gtgtcgtctc cgaggtcgag gtgaccgtcg tccacgagat cgcgcaccac ttcggcatcg
    18001 acgacgagcg gctgcacgag ctggggtacg ggtgagcgca gagggcgggc cggacgggga
    18061 cccggcggga ggaccgcgcg gcccggaaga ctgcggccgg cccctctccg ccggtccgcc
    18121 gccgtggcag gaggccgtcg atcccgacgt cgacctgcac gtaccggctc agcgggccga
    18181 ggccgcgggc cgtcacgggc tggtggtgct cgccgtcatc ggcgcggggg gcgctctggg
    18241 ctccctcggc cgtcacgcgc tcgccctgtg gcttccggcc cgcggcgcca cggggttccc
    18301 gtgggggatc ttcgtcgtca acctctcggg ctgtgccctg atcggcgtgc tgatggccct
    18361 ggtcggcgag ggcggtcgcg acgcccgtgc gccggcgctg ctgaggccgt tcctgggcgt
    18421 cggcgtgctc gggggcttca ccaccttctc gacctacgcg gtcgacgcct cgcatctgct
    18481 ccgggcgggg ccgcacgcgg tgccgatcgc cggcgcgtat ctcggcggga cgctgctggg
    18541 ggcgctggcc gcggtctggg ccggtgcggc ggccacgcgt gcgctgctgg aggtgcgtgg
    18601 gcggtgacat gggtgctggt ggccgtgggc ggcatggtgg gcgccccgct gcggtatctg
    18661 acggaccggg ccgtacaggc gcggcgcgaa tcggtcttcc cctggggcac cttcacggtc
    18721 aacgccgtcg gttgtctgat gctgggcctg ctgacgggcg ccgtggcctc cggagctgcc
    18781 ggttcgcgga tcatggcgtt cctgggcacg gggctgtgcg gggcgctgac gacgtactcg
    18841 acgttctcct acgagacgct gcggctggcc gaacggggcc gcggggggct ggcatcggcg
    18901 aacgccctgc tgtccgtgct ggtcggtctg ggtgccgtgt tcgccggact cgccctggca
    18961 cgcgccgtgt tggcgtgacc tgttgcgcac ggcggcagtt gagcagaggg ctcgccgctc
    19021 ccgtttccgg cgcctggagg ttcccccgtg cgctcgtcca cttccccgtt ccgttcccgg
    19081 gccgcccttt accggccaag tcccgtccgg ctgacgggag ttggcgagcg tgccgctcgt
    19141 acggtcgccg gagtgctgct gctggccctg ctgcagggat gcatgacggt gcacggggac
    19201 gcgggtggag gcagcgacga gcggcgaggc ggaggctcct cctctgacgc gggcgcgggg
    19261 ggcgaggtgc ccgagggcgg attctcgggc agcgtgctgc ggcacggtga gggcgcgcgc
    19321 ggcggcgagg acgcccggcg cgcgcacggc tcccaccggg cacgccacgg ccgcgacgcc
    19381 gacgggaagg acggcggcgg caagcgccgg gcggaggacg gcggcaagcg gcaccgcaag
    19441 aacgggagcg gcaagtccgg tgcggggcac gacagttcgc gtgacacccc gaaggccccg
    19501 gactccccgg cgtcccctcg ccctccgcgt ccgaagccgc cctcgccgcc gaagccgagt
    19561 gtgccgaagc ccactcccac ccagtcgcgg cccccgtcgg aggccccgac gtcgccgacc
    19621 agccgatagt ctcctcccga gcgcccgcgc agccctcgtg atctcatttg cgcagcgccc
    19681 tgcggggtgc gtatgctggt tgatcgtttg atcccatttg cccggcgccc ttgcagagcg
    19741 cgccgcgtgg cgcgtttctc tcagccgtgg ctgaccgcat agaggcggtc gtttgcgaat
    19801 tcacggagtc tgagcgcgtg ctgctgaact ccggaaggtt cgcacttcgc atgtctgttg
    19861 cctcgatcga cgctgtcctg cctcaggacg aggacaccgt caccttcgcc gatctcgggc
    19921 tccccgagcc cgtggtgcgc aagctcgcgc agaacggcgt gaccatcccc tttcccatcc
    19981 aggccgcgac catcccggac gcgctgcggg gcaaggacat cctcggccgt ggccgcaccg
    20041 gctccggcaa gaccctctcc ttcgggctgc cgctgctgaa ccgcctggcc ggcggccgca
    20101 ctgagcgcaa gcgcccccgc gccgtcatcc tcacgcccac gcgcgagctg gccatgcagg
    20161 tctccgacgc gctccagccg tacggtgacg tgctcggcct gaagctcaag gtcgtctgcg
    20221 gtggcacgtc catggcgaac cagatcacgg ctctggaacg cggcgtggac atcctcgtcg
    20281 ccacccccgg ccgcctgcgc gacctgatcg ggcgcggttc ctgctctctc gaggacgtcg
    20341 aggtggccgt gctcgacgag gccgaccaga tgtccgacct gggcttcatg cccgaggtca
    20401 ccgagctgat ggaccaactg ccccagggcg ggcagcggat gctcttctcc gccaccatgg
    20461 agaaggagat cgacacgctc gtcaggcggt acctggacac gcccgtggtg cacgaggtcg
    20521 acgccgccca gggcgcggtc acgaccatga gccaccacgt gctcgtggtg aagccgcgtg
    20581 acaaggcgcc cgtgaccaac gcgatcgcct cgcgcaaggg ccgcacgatc atcttcgtgc
    20641 ggacgcagct cggcgccgac cgcgttgccg agcagctgcg cgagggcggc gtgggcgccg
    20701 aggcgctgca cggcggaatg acgcagggcg cccggacgcg caccatggcc gacttcaagg
    20761 acggcaaggt caacgtgctg gtcgcgacgg acgtggcggc ccgcggcatc cacgtcgaca
    20821 acatcgacct ggtgctgaac gtcgacccgg ccggcgacca caaggactac ctgcaccgct
    20881 ccggtcgtac cgccagggcg gggctgtccg gcaccgtcgt ctcgctggcg ctgccgcacc
    20941 agcggcggca gatcttccgg ctgatggagg acgcgggcgt cgacgcctcg cggcacatca
    21001 tcgggcgggg cgacgtcttc gacgaggaag tgacgcggat cacgggtgcg cgttcgctg
//
