LOCUS       NZ_CP048882            20717 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Streptomyces bathyalis strain ASO4wet chromosome, complete genome.
ACCESSION   NZ_CP048882
VERSION     NZ_CP048882.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces bathyalis
  ORGANISM  Streptomyces bathyalis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7377472)
  AUTHORS   Risdian,C., Landwehr,W., Rohde,M., Schumann,P., Hahnke,R.L.,
            Sproer,C., Bunk,B., Kampfer,P., Schupp,P.J. and Wink,J.
  TITLE     Streptomyces bathyalis sp. nov., an actinobacterium isolated from
            the sponge in a deep sea
  JOURNAL   Antonie Van Leeuwenhoek 114 (4), 425-435 (2021)
   PUBMED   33595745
REFERENCE   2  (bases 1 to 7377472)
  AUTHORS   Risdian,C., Landwehr,W., Schupp,P. and Wink,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2020) Microbial Strain Collection, Helmholtz
            Centre for Infection Research, Inhoffenstrasse 7, Braunschweig,
            Niedersachsen 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-FEB-2019
            Assembly Method                   :: HGAP v. v3
            Assembly Name :: Streptomyces_DSM106605_HGAP3_1SC_10M
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 117.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015910445.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 04:35:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,467
            CDSs (total)                      :: 6,387
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 111
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 37 of 111
            Pseudo Genes (incomplete)         :: 90 of 111
            Pseudo Genes (internal stop)      :: 12 of 111
            Pseudo Genes (multiple problems)  :: 25 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:44:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4060446
            Orig. end                         :: 4081163
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048882.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MISG, Helmholtz Centre for
            Infection Research, Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20717
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="15"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20717
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20717
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10717](-)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10717)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     gene            1475..2971
                     /locus_tag="G4Z16_RS17660"
                     /old_locus_tag="G4Z16_17635"
     CDS             1475..2971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957153.1"
                     /locus_tag="G4Z16_RS17660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17635"
                     /product="N,N-dimethylformamidase beta subunit family
                     domain-containing protein"
                     /protein_id="WP_197351724.1"
                     /transl_table=11
                     /translation="MGQADIRRWESGALAHAVTDPFGQGPLPWLRFGEQYFDNGRMVPW
                     YVDHTGLEDVLSGERIPRSPGVGRPRTADDLHCQIKGFAGSDGGTAPGESLDFRITVDP
                     PQSFGVDIYRIGHYDGDGARKITTSPRLSGIRQPAPLTAGKTVSCHHWWLSWRLQIPED
                     WSTGAYVAVLTTADGCHRSHIPFTVRDRTPGDLLLVMPDITWQAYNLFPEDGRTGASLY
                     HAWDEEGRLLGEEDAAVTVSFDRPYAGAGLPLHVGHAYDFIRWAERQGYELAYADARDL
                     HAGRVDPSRCRGVIFPGHDEYWTVPMRRAVERARDSGTSLVFLSANTMFWQVQLDPLPG
                     GSPDRLLTCRKRRGPGRAAQWRTMGEPEQLVLGIQYTGQVPRPYPLVVRNSDHWLWEST
                     GAADGDELPGLVAGEADCYFPRTSLPEHSERALLAHSPYSDVRGVHRHQETSLYRAPSG
                     ALVFCSGTFAWSPALDRPGHVDPRIQRATANLLDRVSKKG"
     gene            3132..4082
                     /locus_tag="G4Z16_RS17665"
                     /old_locus_tag="G4Z16_17640"
     CDS             3132..4082
                     /EC_number="6.3.2.6"
                     /GO_function="GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313468.1"
                     /locus_tag="G4Z16_RS17665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17640"
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="WP_197351725.1"
                     /transl_table=11
                     /translation="MSGFVEKPDPVQVPGLLHLHTGKVRDLYRNEAGDLVMVASDRISA
                     YDWVLPTEIPDKGRILTQLSLWWFEQLADLVPNHVVSTEVPEGAPADWEGRTMVCRSLR
                     MIPVECVARGYLTGSGLAEYEQTRTVCGLALPEGLTDGSELPGPIFTPATKAAVGDHDE
                     NVSYEEVAREVGAETAAQLRQLTLAVYQRARDVALDRGIILADTKFEFGYRTGDEDGIG
                     VQAESDVGLVLGDEVLTPDSSRFWPADKWEPGQAQASFDKQFVRDWLSGPESGWDRSGE
                     EPPPPLPASIVEQTRTKYAEAYRMLTGLEWFWPLR"
     gene            4356..5348
                     /locus_tag="G4Z16_RS17670"
                     /old_locus_tag="G4Z16_17645"
     CDS             4356..5348
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507247.1"
                     /locus_tag="G4Z16_RS17670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17645"
                     /product="response regulator transcription factor"
                     /protein_id="WP_197351726.1"
                     /transl_table=11
                     /translation="MGTNEMSYLGLTEEQEHMYRLCLREPGIGLDGLIDQLRLPPNAAR
                     RELRRLRELGLLRRQADGLAAADPDVAVARLLDLRLHELHEKLQRVTQLQPLVASLRAE
                     RGEEREPAALGIEQVTDPAKIRDRIDDLAFFAREEVALVEPAVALRQEEIDEARPRVLR
                     CLRRGLTVRTVLVRKALDHEPTVAYLRELESYGARVRLVTHTTAKIQMYDRRTAVVPVD
                     PEETAAGALFAQESGLVSNILALFESIWAESEDLATLLGEWRSEEDAPSELERMVLRAM
                     CSGGKDEAGARDLGVSVRTYRRYIADLMQLLGAGNRPQAALLARERGWV"
     gene            complement(5461..6927)
                     /locus_tag="G4Z16_RS17675"
                     /old_locus_tag="G4Z16_17650"
     CDS             complement(5461..6927)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604054.1"
                     /locus_tag="G4Z16_RS17675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17650"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_197351727.1"
                     /transl_table=11
                     /translation="MTQTVDAAIVGTGPNGLAAAVTLARAGLRVELHEAAASIGGGLRG
                     EAYFDSDVRHDVCSAVHPMAAASPFFREFDLTARGVELLGPEIGYAHPLDDGRAGLAYP
                     DLDATCDGLGEDGRRWRQLMEPLVEHSTGLVDFIMSGQRSLPGDPAAVLLLAARLLPRR
                     ALSGFRGDVAPALLAGVAAHAVGKLPSLAADAVAMLLGHLAHATGWPLPRGGSERIARV
                     MADDVRAHGGTIHTGSHITSLRQLDHARAVLLDTTPTQLLTLAEGRLPAGYARQLRRFR
                     YGPGATKADFLVSEPVPWTNPDVGRAGTVHLGGSHTAIARRERLAVRGEPTDEPFVLLV
                     EPAATDPGRAHKGKRPVWAYAHVPNGDPRDPVALLRSRIEKYAPGFGDTVLAARGVAAR
                     DYESYNPNYVGGDIGAGAMTLYQSLARPVPRLDPWRTPLPGVFLCSASTPPGPGVHGMC
                     GHLAALSALRNRFGVREAPALGPTAPGVRA"
     gene            complement(6924..8945)
                     /locus_tag="G4Z16_RS17680"
                     /old_locus_tag="G4Z16_17655"
     CDS             complement(6924..8945)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991974.1"
                     /locus_tag="G4Z16_RS17680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17655"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_197351728.1"
                     /transl_table=11
                     /translation="MSSTVEAKDTTVSETPRAEEPPEHLGPAHARRRRGGTSPAAVWYL
                     ARRHRGLLAAGIVIGLIGVTAQLAQPYAIGELIKQAAANKPLATAVLILVGLFCVDGAF
                     SALQSYLIGRAGENVVYDVRMLLTRRLLHVDLSAYSKQQQGDVLTRTVSDTSLAKIALS
                     QSLAQLVINGFTVAGGVVVMFLIDVWMMLITLACLGIASGVSLMLARSVRRAAVVNRED
                     TSAYGSDVQRALSALPTVKASRAEDRETNRIGLLAWRARNSGVRVNGLNALFMPAMNVG
                     TQAALAVVVGVGMTRVTRGTMSMADLTAFVMYLFYMVSPLVLFFLAIGQFQQGRAAIRR
                     VDELTTLPQEGGVLDRMRHRPKPPSTSSLSADQDAVEFRSVHFSYGGKDEKNGEGGEGS
                     SGGDAQQPAETLSDVTFSVAARGMTAVVGPSGAGKTTLFQLIERFHALDSGSITVGGKD
                     IETMPLSTLRGLVGYVQQDTAAMRGSVRDNVVYATPDASDEDVRQVIELAGLTKVVSEL
                     PQGLDTELGDQGSGLSGGQRQRLCIARALLQKPAVLLLDEATSHLDSDSEREFRETLRK
                     VSARCAVIAIAHRISTVVDADMIVVMNEGRVQAVGQHDELMKRDALYYRLANSQLQAAT
                     STASWPTDPTGMPGFAGAAGQNGNGTPVHNGTPVGGSR"
     gene            complement(8953..9711)
                     /locus_tag="G4Z16_RS17685"
                     /old_locus_tag="G4Z16_17660"
     CDS             complement(8953..9711)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453461.1"
                     /locus_tag="G4Z16_RS17685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17660"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_197351729.1"
                     /transl_table=11
                     /translation="MSSVDDIGYGRQFGDFYDRIFPSGAYTEPTVRKLASLHPDPGERA
                     LELGVGTGRVAIPLAQRAFPVTGVDSSPEMLEQLTAKAKEANADVEAVHGDIRKYTDDT
                     KYQLVYCVCATFSMILEADDQRAVMQHAADRLAPGGVLVVETSNPGGLRALHEGQQRTS
                     YFIPYPEPNTGLLTYSTVFEDRSLWHASHIWFEDGKSSVGSELARLTTPEEVDEYAAAA
                     GLKPVDRWADWEETPYAEDSPMFVSTYTAR"
     gene            complement(10001..10717)
                     /locus_tag="G4Z16_RS17690"
                     /old_locus_tag="G4Z16_17665"
     CDS             complement(10001..10717)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132582.1"
                     /locus_tag="G4Z16_RS17690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17665"
                     /product="hypothetical protein"
                     /protein_id="WP_197351730.1"
                     /sec_met_domain="cypI (E-value: 1.1e-30, bitscore: 105.2,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTPTPAVPGAVAGTLVRAARGARSGLSRAFTGPGGLTRAAGAA
                     LLLGTLSAQHPNPLFNKAQKMDIFSGMFPNWRFFAPTPAQHDYHILYRTLNHEGETSPW
                     RMVEVIVGRKLPQIFWFPGRRPEKAIFDIVTELITQLDKGFSGMMKLPSYRILCAYLRH
                     RIREDGNAEGVKGFQFTLVRATGYEETDPEVVFVSPYTQMKGPDEAAAGGTSGWGPSYD
                     SHIRDDSRGEVPAQPA"
     gene            complement(10714..12651)
                     /locus_tag="G4Z16_RS17695"
                     /old_locus_tag="G4Z16_17670"
     CDS             complement(10714..12651)
                     /NRPS_PKS="Domain: Abhydrolase_1 (368-468). E-value:
                     6.8e-13. Score: 40.7. Matches aSDomain:
                     nrpspksdomains_G4Z16_RS17695_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435953.1"
                     /locus_tag="G4Z16_RS17695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17670"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_197351731.1"
                     /sec_met_domain="Thioesterase (E-value: 1.6e-07, bitscore:
                     30.3, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-15, bitscore:
                     56.9, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.3e-09, bitscore: 36.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSLAKKLTSTFLGPVPVSRSRALAISERLTAVTSLTSSLEYITH
                     QRQIRRGGLNDWTIARGMHASSTRPTRRLLDAVGNPRTTKALHVARIAASAALLAPGNA
                     RWRGAANVFLGLSNAALYPRHRYGTDGSDQVSSFVQTAAGLARLSSQPAVQDALLWYVA
                     LQANLSYLVSGWVKLLGEPWRDGSALNGIMRTRTYGHEGLWKLTNRYPVPARYLAHGVL
                     ALECLFPVAYLKGGMLARPVMASAAAFHVANGYFMGLGRFITAFEAMHPMVAYTSAPKS
                     HPAVAGRDDRMLKATASMAAIGVTVAGFLAAMRRMRATDPWPHGRVLTTRHGNELHYNE
                     RVSEDDSSPVLVFGTGMISTMEHFGWITDKLVEESDYGIITYSRAGYGPSKRRSSSPFT
                     LQESVDDLVDLVEGAVAKGRPVYLVGHSLGGEIGRRAAAELGDRIRGVIYLDSSHPDEL
                     TRSKQQQDSADRLKDGLNMLSGSLRAGLGATLVRPRWVHDLPAEVRSRAFAQYADSRLW
                     RAGLREWDATEADFHRFSGDLPAISAHALVLSAQRTVDRDPEQLLMHNELGAAHRGEGR
                     IVHNSVIEGADHDTMLTDARLGGDVGRRILEFLREVEGHDGDADSAAGGSRGSAKGTHG
                     SKGNQSKEAR"
     aSDomain        complement(11248..11547)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G4Z16_RS17695_Abhydrolase_1.1"
                     /evalue="6.80E-13"
                     /label="G4Z16_RS17695_Abhydrolase_1.1"
                     /locus_tag="G4Z16_RS17695"
                     /protein_end="468"
                     /protein_start="368"
                     /score="40.7"
                     /tool="antismash"
                     /translation="DKLVEESDYGIITYSRAGYGPSKRRSSSPFTLQESVDDLVDLVEG
                     AVAKGRPVYLVGHSLGGEIGRRAAAELGDRIRGVIYLDSSHPDELTRSKQQQDSA"
     CDS_motif       complement(11338..11397)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G4Z16_RS17695_0001"
                     /evalue="1.00E-03"
                     /label="NRPS-te1"
                     /locus_tag="G4Z16_RS17695"
                     /protein_end="438"
                     /protein_start="418"
                     /score="11.7"
                     /tool="antismash"
                     /translation="RPVYLVGHSLGGEIGRRAAA"
     misc_feature    12636..12650
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    complement(12638..12649)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            complement(12964..13143)
                     /locus_tag="G4Z16_RS17700"
                     /old_locus_tag="G4Z16_17675"
     CDS             complement(12964..13143)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G4Z16_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="G4Z16_17675"
                     /product="hypothetical protein"
                     /protein_id="WP_028437555.1"
                     /transl_table=11
                     /translation="MKDVTSQINESAELASVAITDAEGVVFTDYTPVMGTPGAFLGGVA
                     IASATVAAFEAGQD"
     gene            complement(13250..13423)
                     /locus_tag="G4Z16_RS17705"
                     /old_locus_tag="G4Z16_17680"
     CDS             complement(13250..13423)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G4Z16_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="G4Z16_17680"
                     /product="hypothetical protein"
                     /protein_id="WP_158677079.1"
                     /transl_table=11
                     /translation="MLEEKLNLQIQDQLHEAHEGEIAEEAAPVLATPALAGAFVGGAAV
                     VTGAYAAGKAVG"
     misc_feature    13389..13403
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    13704..13719
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.82"
                     /tool="antismash"
     misc_feature    complement(13787..13801)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.36"
                     /tool="antismash"
     gene            complement(14155..14751)
                     /locus_tag="G4Z16_RS17710"
                     /old_locus_tag="G4Z16_17685"
     CDS             complement(14155..14751)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946147.1"
                     /locus_tag="G4Z16_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17685"
                     /product="response regulator transcription factor"
                     /protein_id="WP_197354716.1"
                     /transl_table=11
                     /translation="MLLADDEHLIRGALTALLALEEDLTIVAEAASGPEAVAMARAHAP
                     DVAVLDLQMPGADGVQVATQLRDELPACRTMIVTSHARPGHLKRALAAGVRGFVPKTAS
                     AQQLAEIIRAVHGGTRYVDPELAADAISTGDSPLTARETELLALAAGGAPVADIAERVS
                     LTPGTVRNYLSAATAKLGAENRHAAARKARERGWL"
     gene            complement(14805..16142)
                     /locus_tag="G4Z16_RS17715"
                     /old_locus_tag="G4Z16_17690"
     CDS             complement(14805..16142)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014178304.1"
                     /locus_tag="G4Z16_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17690"
                     /product="histidine kinase"
                     /protein_id="WP_246530919.1"
                     /transl_table=11
                     /translation="MIGWWGVAPKYRRWQERSSHEQVEASTRWMLVAYAWLTLVGFVVQ
                     LVPNAGPGALPRTLAWTVLGLGLVQCLLCTGVLHRAIDSYLGTRTVTDARLALPAVLMA
                     SMTALTVVLVAIRAVEVGLEVGLGLHGALAPFAVTFGVAVPRRTAALALSGYLAATTAA
                     LAAAGLPGADLLAALVVVGLGGLLSVFTGRSSAWYIAVIRELEEARGVQARLAVAEERL
                     RFSRDLHDVMGRNLSAIALKSELAAQLVRRGSETEASVGQMTEVQRIAREAQSEVRAVV
                     RGYRDVDLPTELAGARGILRAAGVDCRTDNGGSQLPAPVQAALGWVVREGATNVLRHAD
                     ATWCTVWVGTDPAGRSALLVMENDGTRGQAPGGSAGSGLAGLRERLDGVGGTLRVARDG
                     ESGTFRLTAEVPLAAGNDATADEAVTDPAGTAGTHGSGTDGKDSAE"
     gene            complement(16165..16977)
                     /locus_tag="G4Z16_RS17720"
                     /old_locus_tag="G4Z16_17695"
     CDS             complement(16165..16977)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991329.1"
                     /locus_tag="G4Z16_RS17720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17695"
                     /product="ABC transporter permease"
                     /protein_id="WP_197351732.1"
                     /transl_table=11
                     /translation="MSSTDAATVKAPGRVDTSAMWSRLRALGRAELTLLMRNKAMLFVA
                     LATPALLTVLMRQTASGMNLEGTGLSLGTVLVPGSIGYVLVFAVYANLTGIYVTRREEL
                     VLKRLRTGEASDGEILTGSALPSLVLALGQCVLLLGGGAVLLDLAPPERPELVAAGLLL
                     GLLLMVLLAAVSAAFTRTTEASQITTFPFMAISFVGSGVVVPLDVMPDVLANVCSLLPV
                     SPTMELVRNGWVGTLSGMDTVKALTVLVVWIILGTVAVRRWFRWEPRR"
     gene            complement(16974..17960)
                     /locus_tag="G4Z16_RS17725"
                     /old_locus_tag="G4Z16_17700"
     CDS             complement(16974..17960)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985570.1"
                     /locus_tag="G4Z16_RS17725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17700"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_197351733.1"
                     /transl_table=11
                     /translation="MDAIEVDGLKRRYAKGFEAVRGVSFSVREGEIFALLGTNGAGKTS
                     TVELLEGLARPSGGNVRVLGFDPYSERTAVRPRTGVMLQEGGFPSELTVTETIRMWAGC
                     TSDARPIGEVLAQVGLSDRRAQVRVKQLSGGERRRLDLAMALVGHPEVLFLDEPTTGMD
                     PEGRRDTWDLVRELRRAGTTVLLTTHYLEEAEELADRLAIMRAGRIVTTGTPEQVVAER
                     PSSIRFTLPDGLSPAHLPTTLPQPTLREGRVEIRTPQLQSALTDLLIWARQAGVELPGL
                     HARTATLEEVFLEIAQLPDEADEDSQAGGPGKHRAGAASGGMEVERV"
     tRNA            complement(18222..18297)
                     /anticodon=(pos:complement(4078708..4078710),aa:Gly,
                     seq:gcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="G4Z16_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="G4Z16_17705"
                     /product="tRNA-Gly"
     gene            complement(18222..18297)
                     /locus_tag="G4Z16_RS17730"
                     /old_locus_tag="G4Z16_17705"
     tRNA            complement(18400..18471)
                     /anticodon=(pos:complement(4078883..4078885),aa:Gly,
                     seq:tcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="G4Z16_RS17735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="G4Z16_17710"
                     /product="tRNA-Gly"
     gene            complement(18400..18471)
                     /locus_tag="G4Z16_RS17735"
                     /old_locus_tag="G4Z16_17710"
     gene            complement(18612..18929)
                     /locus_tag="G4Z16_RS17740"
                     /old_locus_tag="G4Z16_17715"
     CDS             complement(18612..18929)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009189439.1"
                     /locus_tag="G4Z16_RS17740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17715"
                     /product="Lsr2 family protein"
                     /protein_id="WP_028437558.1"
                     /transl_table=11
                     /translation="MAQRVVVTLSDDLDGGEASETVSFGLDGKSYEVDLNIENAKKLRE
                     DLARFVEAGRKRAKSGKAYHRTAVAPDPRAVRAWAESNGFEVPARGRIPKKVYDAFNAS
                     R"
     misc_feature    complement(19006..19022)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.82"
                     /tool="antismash"
     misc_feature    complement(19035..19053)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    19054..19066
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.61"
                     /tool="antismash"
     misc_feature    19112..19127
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    19176..19191
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     gene            19312..19569
                     /gene="purS"
                     /locus_tag="G4Z16_RS17745"
                     /old_locus_tag="G4Z16_17720"
     CDS             19312..19569
                     /EC_number="6.3.5.3"
                     /codon_start=1
                     /gene="purS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980566.1"
                     /locus_tag="G4Z16_RS17745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17720"
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="WP_028437559.1"
                     /transl_table=11
                     /translation="MARVVVDVMLKPEILDPQGQAVQRALPRLGFEGIEGVRQGKRFEL
                     EVAEPVTDEALARIHELAGTFLANTVIENYTVRVEEGAAA"
     gene            19566..20252
                     /gene="purQ"
                     /locus_tag="G4Z16_RS17750"
                     /old_locus_tag="G4Z16_17725"
     CDS             19566..20252
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /GO_function="GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="purQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547974.1"
                     /locus_tag="G4Z16_RS17750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4Z16_17725"
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="WP_197351734.1"
                     /transl_table=11
                     /translation="MSGGLGRIGVVTFPGSLDDSDARRAVRLAGGEPVELWHRDKDLRQ
                     VDAVVLPGGFSYGDYLRCGAIARFSPVMEPLLEQARAGMPVLGICNGFQVLCESHLLPG
                     ALTRNDHLHFICRDQKLRVERTDTAWTSDYAEGQKITVPLKNGEGGYVADEHTLDALEA
                     EGRVVFRYLNGNPNGSRRDIAGISNEAGNVVGLMPHPEHAVETLTGPTTDGLGFFTSVL
                     KRLVTA"
ORIGIN
        1 gccctgccgt ctctcccacc gtccccgtcg aggagagctc cgcaaccgac ctgtacgacc
       61 tggtgcggga tctggccgag cggctggagg tcccggtgcc ctccgcagtg gccctcaccc
      121 cggactgcga cagctggctc gaggaccgct cgcaccgcac ccgcgggcgc gtggctcccg
      181 tgctggtcat cggctcgccc ttcctgtggt ggatgagggt ggccgaactg cgcgccctgc
      241 tggcacccgt ggtcgcgggc accggacctt ccctgcatcc cgacatagcc gcggcccgcc
      301 ggttcgtccg ggggctggac gcggcggtcg ccgtggccga caaggcacgc gccgggcggt
      361 ccggcacgtc agggccgggt gcggcggtgc gccgggccgg tctccgcttc gcgggcggct
      421 gctcccggtt gatgctccgc gcgtgcgggc cgcacgcggc cgagatggag cgcggggtcg
      481 ccgccgcggc cgccgcccgt gcacagggtg tggatcacgc gctgcgtacg gcggcgcagg
      541 aacaggtcgg cctcgcatac gcgggctggg acaggctgct gacgcgggtc gccctgcccg
      601 cctggcgtat cggccggtgg ccggcccgtc tcgatgcggg ggtggtctcg gcgctgacgg
      661 acctctcaca ccgggacagg ctcgcggaag gcttcacctc gcgcctgggc gagcgccccg
      721 cctgcgatct gctcgacgag ccgggcaccg tcgacgaagc ggtctcgctg ctcgccgccc
      781 gcctcttcca cggaggaccg ccggagccgg ggcccgactg ggcgcccgtg gactggcagg
      841 agtacccgga ggaggtcgtc gaccgcatct ggcgcacccg cgcctcccgg ctcttcacgc
      901 acctgaccgc gctcgaccgt cccggcagcg gctctgtgga cggcggagcg accccggccc
      961 ggatcatgga gtggctgacg ggcggcccgg tggcccgtac ggaagagctc gcggcccgca
     1021 taggtgccgc cgtcgcccgt gagacctcgc ccgaatcgtg ggaggacgcg ctcgtggcgc
     1081 cgctcatagc cggcgtgggc gacggagccg gcgtctcgcc catgggcctc ccgctccagg
     1141 ctccccgcag cgggcgcgag ttgatgctgg agcacatcac cgccgtgatc tgctgcgcgg
     1201 ccgtggacac ggccggcgcc gtccccggtc tcgactggct cgacggcccg gcgctcctcg
     1261 tcgacggtgc gcgcgcggcc gacctgacga gccccgtgct cgaactcgtc gaggcaggcg
     1321 acccccagcc gctccgggag tggatggccg cggtgggagt ccggccggac aagcccgttc
     1381 gcctcgtatg atgccgggcg gtgacgcacc gctcgcgtaa tgtgatggtg tggctctgtc
     1441 gggggtgtcg acgagcaggg gggttgagtc acaagtgggc caggcagaca tccggcgctg
     1501 ggagtccggg gcgcttgcgc acgcggtcac ggacccgttc ggccaagggc cgctgccctg
     1561 gctgcgcttc ggcgagcagt acttcgacaa cggccgcatg gtcccctggt acgtggacca
     1621 caccggcctc gaggatgtgc tctccggcga gcggatcccg cgcagcccag gggtgggccg
     1681 cccccgcacc gctgacgacc tgcactgcca gatcaagggc ttcgcgggca gcgacggcgg
     1741 cacggccccg ggtgagtcgc tcgacttccg catcactgtc gacccgccgc agtccttcgg
     1801 cgtcgacatc taccgcatcg gccactacga cggcgacggc gcgaggaaga tcaccaccag
     1861 cccgcgtctg tcgggcatcc gccagccggc cccgctcacc gccgggaaga cggtctcctg
     1921 ccaccactgg tggctctcct ggcgcctgca gatccccgaa gactggtcaa ccggtgccta
     1981 cgtcgccgtc ctcaccaccg ccgacgggtg ccaccgctcg cacatcccct tcaccgtccg
     2041 cgaccgcacg cccggggacc tgctcctcgt catgccggac atcacctggc aggcctacaa
     2101 cctcttcccc gaggacggtc gcaccggcgc gagcctgtac cacgcgtggg acgaggaggg
     2161 ccggctgctg ggcgaggagg acgccgccgt cacggtctcc ttcgaccgcc cctatgccgg
     2221 agccggcctg cccctgcacg tcggccacgc ctacgacttc atccgctggg ccgagcgcca
     2281 gggctacgag ctcgcatacg ccgatgcccg cgatctgcat gcgggccgcg tcgatccgtc
     2341 ccgctgccga ggcgtcatct tccccggcca cgacgagtac tggacggtgc ccatgcgccg
     2401 tgcggtggaa cgggcgcgcg actcggggac ctcgctggtc ttcctgtccg ccaacaccat
     2461 gttctggcag gtccagttgg acccgctgcc cggcggctcc cccgaccggc tgctgacgtg
     2521 ccgcaagcgc cggggccccg gccgcgccgc ccagtggcgc accatgggcg aacccgaaca
     2581 gctcgtgctg ggcatccagt acaccgggca ggtgccccgc ccgtacccgc tggtggtgcg
     2641 caacagcgac cactggctgt gggagtccac cggtgcggcc gacggagacg aattgcccgg
     2701 cctggtcgcc ggtgaggccg actgctactt cccccgcacg agcctgccgg agcactccga
     2761 gcgtgcgctg ctcgcgcact ccccgtacag cgacgtgcgg ggcgtccacc gccaccagga
     2821 gacgtcgctc taccgggctc cctccggggc actggtcttc tgctccggca ccttcgcctg
     2881 gtcgccggcg ctcgaccgtc ccggccacgt cgacccccgc atccagcggg cgacggccaa
     2941 cctcctcgac cgggtgagca agaagggctg agggagccgc aggcagaggc cctggcccgc
     3001 cgcgttccac ccgcccccga gaggtgtgcg aacccctcgt acgggacaat cgggagctga
     3061 agcgctcccc cctttccccc actgttcgcc gggggcaccg gagggagacc ctgaccgacc
     3121 ccggaggacc cgtgtccgga ttcgtggaga agcccgaccc cgtgcaggtc ccgggcctgc
     3181 tgcatctgca caccggcaag gtgcgcgatc tgtaccgcaa cgaggcgggc gacctcgtca
     3241 tggtggccag cgaccgcatc tccgcatacg actgggtgct gccgaccgag atccccgaca
     3301 agggcaggat cctcacccag ctgtccctgt ggtggttcga gcagctcgcg gacctcgtcc
     3361 ccaaccacgt cgtcagcacc gaggtgcccg agggcgcccc tgccgactgg gaggggcgca
     3421 ccatggtgtg ccgctcgctg cgcatgatcc cggtggagtg cgtcgcgcgc ggctacctga
     3481 ccggttcggg tctcgcggag tacgagcaga cccgtacggt ctgcggactc gcactgcccg
     3541 aagggctcac cgacggctcg gagttgccgg gcccgatctt cacgcctgcc acgaaggcgg
     3601 ccgtcggcga ccacgacgag aacgtcagct acgaggaggt cgcccgcgag gtcggagccg
     3661 agaccgccgc ccagctgcgg cagttgacgc tcgccgtcta ccagcgcgcc cgcgacgtcg
     3721 ccctcgacag gggcatcatc ctcgccgaca cgaagttcga gttcgggtac cggacgggtg
     3781 acgaggacgg catcggcgtg caggccgagt cggacgtcgg cctggtcctc ggcgacgagg
     3841 tgctcactcc cgactcgtca cgcttctggc ccgcggacaa gtgggagcca gggcaggcgc
     3901 aggcgtcctt cgacaagcag ttcgtccggg actggctctc cgggccggag tccgggtggg
     3961 acaggagcgg tgaggagcct ccgcctccgc tgccggcgag catcgtggaa cagacccgca
     4021 cgaagtatgc ggaggcgtac cggatgctca ccgggctcga gtggttctgg ccgctgcgct
     4081 gacgcgccgg tgcgggccgc cggaagaccc gtcgtgatcc acgagccgaa cgcgaggcgc
     4141 gatttccgga gttgaatcct ccgtccggga cggtgcatac gggggcagat gcgcaccata
     4201 cgaagggccc tttcgaaaag gtctcccttt gaggggtgtt cgtcgccttc gttttttcta
     4261 tgctcggaga cctgttccgc atgtgggtgc ccaagttctg accaccgccc atgtgcaggg
     4321 gtccaggcgg ggtgaccgga cagggggaat tcaccttggg tacgaacgag atgtcctatc
     4381 tcggcctcac cgaggagcag gaacacatgt accggctctg tctgcgtgag cccggcatag
     4441 gactcgacgg cctcatagac cagctccggc tgccgcccaa cgcggcacgc agggagctgc
     4501 gcaggctgcg tgaactgggc ctgctgcgaa gacaggccga cggactcgcc gcggcggacc
     4561 cggacgtggc agtggccagg ctgctcgacc tgcgcctgca cgaactgcac gagaagctgc
     4621 aacgcgtcac gcagctccag ccgttggtgg cgtcgttgcg cgcggagcgc ggcgaggagc
     4681 gagagccggc cgccctcggc atcgagcagg tcaccgaccc cgcgaagatc cgcgaccgca
     4741 tcgacgacct ggccttcttc gcccgcgaag aggtcgctct cgtggagccg gccgtcgcgc
     4801 tgcggcagga ggagatcgac gaggcacgcc cgcgtgtgct gcgctgcctg cgaagagggc
     4861 tgacggtgcg caccgttctc gtccgcaagg ccctcgacca cgagccgaca gtggcgtatc
     4921 tgcgtgaact ggagtcgtac ggggcacggg tgcggctggt cacccacacc acggcgaaga
     4981 tccagatgta cgaccgccgc accgccgtcg tacccgtcga ccccgaagag accgccgccg
     5041 gcgcgctgtt cgcgcaggag agcgggctgg tctccaacat cctcgccctc ttcgagtcga
     5101 tctgggcgga gtcggaggac ctggcgacgc tgctggggga gtggagatcc gaagaggacg
     5161 cgccttccga gctggagcgg atggttctgc gagcgatgtg ctccgggggc aaggacgagg
     5221 cgggggcgcg cgacctgggt gtctcggttc gtacctaccg gcgctacatc gcggacctga
     5281 tgcagctgct cggcgccggc aaccgtccgc aggcggcgct gctggcgcgg gagcgcggct
     5341 gggtctgacg ggcggtcgcg tcggggccgg ttcgccgggt ggttcatagg gccggaggcg
     5401 gtggcggcgg ggccggcgcc gctgtcgctc cccctccggg acgggggccc ggcgccggtc
     5461 tcaggcccgt acgcccggcg cggtcggccc cagcgccggt gcctcacgca cgccgaagcg
     5521 gttccgcagc gcggagagcg cggccagatg accgcacatg ccgtgcacgc cgggcccggg
     5581 cggcgtcgag gcggagcaga ggaagacgcc cggaagcggg gtgcgccagg ggtcgagcct
     5641 gggaaccggc cgcgccagcg actggtacag cgtcatcgca ccggctccga tgtcgccgcc
     5701 cacatagttg gggttgtacg actcgtagtc gcgcgccgcg acgccgcgtg ccgcgagcac
     5761 ggtgtcgccg aagcccgggg cgtacttctc gatgcgtgag cgcagaaggg ccaccgggtc
     5821 ccgcgggtcg ccgttcggaa cgtgcgcgta cgcccacact ggccgcttgc ccttgtgcgc
     5881 acgcccggga tcggtggccg ccggctccac gagcagcacg aacggctcgt cggtgggttc
     5941 gccccgtacc gccagccgct ccctgcgggc gatcgcggtg tggctgccgc ccaggtggac
     6001 ggtgccggcg cggcccacgt ccggattggt ccacgggacg ggctccgaga cgaggaagtc
     6061 ggccttcgtc gcacccggcc cgtagcggaa acgcctcaac tgccgtgcgt agcccgccgg
     6121 gagacgccct tcggcgaggg tgagcagctg ggtcggagtg gtgtcgagca ggacggcgcg
     6181 cgcgtggtcg agctggcgca ggctggtgat gtgcgagccg gtgtggatgg tgccgccgtg
     6241 cgcccgtacg tcgtcggcca tgacccgggc gatgcgttcg ctgcccccgc gcggcagcgg
     6301 ccagccggtc gcgtgcgcga ggtgacccag cagcatcgcg acggcgtccg cggcgaggga
     6361 gggcagcttg cccacggcgt gcgcggcgac tcccgcgagc agcgccgggg cgacatcccc
     6421 gcggaagccg ctgagcgccc ttcggggaag cagccgcgcc gcgagcagca ggacggcggc
     6481 gggatcgccc ggcagggacc gctggccgct catgatgaag tccaccaggc ccgtgctgtg
     6541 ttcgaccagc ggctccatca gctgccgcca gcgccggccg tcctccccga ggccgtcgca
     6601 ggtggcgtcc aggtcggggt atgccaggcc ggcgcgtccg tcgtccagcg gatgcgcgta
     6661 gccgatctcg gggccgagga gttccacgcc gcgggccgtg aggtcgaact cgcggaagaa
     6721 cggggaggcg gcggccatgg gatggacggc ggagcacacg tcgtgccgga cgtcgctgtc
     6781 gaagtacgcc tcgccgcgca ggccgccgcc gatggaggcg gcggcctcgt gcagctcgac
     6841 ccgcaggccg gcccgtgcca gcgtcaccgc ggcggcgagc ccgttcggac cggtgccgac
     6901 gatcgccgca tcgacggtct gcgtcaccgc gacccgccga cgggcgtgcc gttgtgcacc
     6961 ggcgtcccgt tcccgttctg acccgcggca cccgcgaacc ccggcatgcc ggtcgggtcc
     7021 gtgggccagg aagcggtcga agtggcggcc tgcagctgcg agttggcgag ccggtagtag
     7081 agcgcgtccc gcttcatgag ctcgtcgtgc tggcccacgg cctgcacacg gccctcgttc
     7141 atcaccacga tcatgtcggc gtcgacgacg gtcgagatgc ggtgcgcgat cgcgatcacg
     7201 gcgcagcggg cggagacctt gcgcagcgtc tcgcggaact cccgttcgga gtcggagtcc
     7261 agatgggagg tggcctcgtc gaggaggagc accgcgggct tctgcagcag cgccctcgcg
     7321 atgcacaggc gctgccgctg cccgccggag aggccgctgc cctggtcgcc cagttcggtg
     7381 tccagcccct ggggcagctc gctgacgacc ttggtgagtc cggccagttc gatgacctgg
     7441 cgtacgtcct cgtcgctggc gtcgggcgtc gcgtacacca cgttgtcgcg cacggagccg
     7501 cgcatggccg cggtgtcctg ctgcacgtag ccgacgagtc cccggagcgt ggacagcggc
     7561 atcgtctcga tgtccttgcc gccgaccgtg atgcttccgg agtccagcgc gtggaaacgc
     7621 tcgatcagct ggaagagcgt ggtcttcccg gcgccggacg ggccgacgac cgcggtcatt
     7681 ccgcgggcgg ccaccgagaa ggtgacgtcg gagagcgtct cggccggctg ctgggcgtcg
     7741 ccgcccgaac ttccctcgcc gccctcgccg ttcttctcgt ccttgccccc gtagctgaag
     7801 tgcacggagc ggaattccac ggcgtcctgg tccgccgaga gcgacgaagt ggacggaggc
     7861 ttcggccggt gccgcatcct gtcgagcacg ccgccctcct gcggaagggt ggtgagctcg
     7921 tcgaccctgc ggatcgcggc gcgcccctgc tggaactggc cgatggccag gaagaagagc
     7981 accagggggg agaccatgta gaagagatac atcacgaagg cggtgaggtc cgccatcgac
     8041 atcgtcccgc gggtcacccg cgtcatgccg acgccgacga cgacggcgag cgccgcctgc
     8101 gtacccacgt tcatggcggg catgaagagc gcgttgaggc cgttgacccg caccccggag
     8161 ttgcgtgcgc gccaggccag caggccgatg cggttcgtct cgcggtcctc cgcgcgggat
     8221 gccttgacgg tgggcagagc cgacagcgcg cgctgcacgt ccgagccgta ggcgctggtg
     8281 tcctcgcggt tgacgaccgc cgccctgcgc acgctgcgcg ccagcatcag tgagacgccg
     8341 ctggcgatgc cgaggcaggc cagcgtgatc agcatcatcc acacgtcgat caggaacatc
     8401 acgacgacgc cgcccgccac cgtgaatccg ttgatgacga gctgcgccag gctctgcgac
     8461 agcgcgatct tcgcgagcga ggtgtccgag accgtacgtg tgaggacgtc gccctgctgc
     8521 tgcttgctgt aggcggacag gtccacgtgc agcaggcgtc tggtgagcag catgcgcacg
     8581 tcgtagacga cgttctcgcc ggcccggccg atcagatacg actggagcgc cgagaacgcg
     8641 ccgtcgacgc agaacaggcc cacgaggatc aggaccgccg tggcgagtgg cttgttcgcg
     8701 gccgcctgct tgatcagttc accgatcgcg tacggctgcg cgagctgcgc cgtcacaccg
     8761 atcaggccga tgacgatgcc cgcggcgagt agcccgcggt ggcgccgcgc caggtaccag
     8821 acggcggccg gactggtgcc gccccgccgt ctgcgcgcgt gcgccgggcc aaggtgctcc
     8881 ggtggctcct ccgcacgggg agtctcggaa accgtcgtgt ccttcgcctc cacggtgctg
     8941 ctcatgccgg ggtcacctcg ccgtgtaggt gctgacgaac atgggggagt cctccgcgta
     9001 gggcgtctcc tcccagtccg cccagcggtc gaccggcttc aggccggcgg ctgccgcgta
     9061 ctcgtccacc tcctccggcg tggtgagccg ggccagttcg gagccgacgg aggacttgcc
     9121 gtcctcgaac cagatgtgcg aggcgtgcca gagactgcgg tcctcgaaga cggtggagta
     9181 cgtcagcaga cccgtgttcg gctccgggta ggggatgaag tacgaggtgc gctgctgccc
     9241 ctcgtgcagg gcccgcaggc cgcccgggtt cgacgtctcc acgacgagga cgccgccggg
     9301 agcgagccgg tccgcggcgt gctgcatgac ggcccgctgg tcgtcggcct cgaggatcat
     9361 cgagaaggtc gcgcagacgc agtagaccag ctggtacttc gtgtcgtcgg tgtacttgcg
     9421 gatgtcgccg tgcaccgctt cgacgtcggc gttcgcctct ttcgccttcg ccgtgagctg
     9481 ttcgagcatc tcgggcgagg agtcgacgcc tgtcacggga aaggcccgtt gggccagggg
     9541 tatcgccacc cggccggtgc ccacgccgag ttcgagggcg cgttcaccgg ggtcggggtg
     9601 cagggaggcg agcttgcgca cggtcggctc ggtgtacgcg ccgctcggga agatccggtc
     9661 gtagaagtct ccgaactgcc gcccgtagcc tatgtcgtcc acagagctca tcaggggccc
     9721 cctctcggtc ttgtggtgcg ggccttccgc tgtgcttcgc cgggggtttc cggctccctg
     9781 gccttccggt cgtccggctt ccggtggttc ggggagccgg ggcgggctac ttcttcttgc
     9841 tgttcttgga gacgttcagc gcgatggcgg cgacgacgat gatggcgatg acggagatga
     9901 cgatcgagcc catggacatg tgcttcgacc cctttcggaa tccggtgctg gttcacccgc
     9961 cggcgcaggc gcgcaggcgg acacttgtgc gtactgctgg tcaggccggc tgtgcgggta
    10021 cctccccgcg cgagtcgtcc cttatgtgcg agtcgtagga gggcccccag ccggaggtcc
    10081 cgccggcagc cgcctcgtcc gggcccttca tctgggtgta cggggagacg aagacgacct
    10141 cggggtcggt ctcctcgtaa ccggtggccc gcacgagcgt gaactggaag cccttcacgc
    10201 cttcggcgtt gccgtcctca cggatgcggt ggcgcagata ggcgcagagg atccggtagg
    10261 agggcagctt catcattccg ctgaagccct tgtccagctg ggtgatgagc tcggtgacga
    10321 tgtcgaagat ggccttctcg gggcggcgtc ccgggaacca gaagatctgc gggagcttgc
    10381 ggccgacgat gacctccacc atccgccagg gggaggtctc cccttcgtgg ttcagcgtcc
    10441 tgtacaggat gtggtagtcg tgctgcgccg gagtgggcgc gaagaagcgc cagttgggga
    10501 acatccccga gaagatgtcc atcttctggg ccttgttgaa cagcgggttg ggatgctgcg
    10561 ccgacagcgt gcccagcaac agcgccgccc ccgccgcgcg cgtcaggccg cccggcccgg
    10621 tgaacgcgcg ggagagaccg gaccgggccc cgcgggccgc gcggaccagg gtcccggcga
    10681 ccgcgccggg aacagccgga gttggggtgc tggtcatcgt gcctccttgg actggttccc
    10741 cttggagccg tgagtgccct tggccgatcc gcggcttccc ccggccgcgc tgtcggcgtc
    10801 gccgtcgtga ccctcgacct cgcgcaggaa ctccaggatc cggcggccca cgtccccgcc
    10861 cagccgggcg tcggtgagca tggtgtcgtg atcggctccc tcgatcacgg agttgtggac
    10921 gatgcgcccc tcgccccggt gggccgcgcc gagttcgttg tgcatcagca gctgctcggg
    10981 gtcgcggtcg acggtccgct gcgccgacag caccagcgcg tgtgcgctga tcgccggcag
    11041 gtcaccgctg aaccggtgga agtcggcctc ggtggcgtcc cattcgcgca acccggcccg
    11101 ccacagcctg ctgtccgcgt actgcgcgaa ggcgcggctg cgcacctccg cgggcaggtc
    11161 atggacccag cggggacgca ccagcgtggc cccgagaccg gcgcgcaggc tgccgctcag
    11221 catgttcagg ccgtccttga gccggtcggc ggagtcctgc tgctgcttgg agcgggtcag
    11281 ctcgtccggg tgcgagctgt cgagatagat cacgccgcgt atgcggtcgc cgagttcggc
    11341 tgccgcccgc cggccgatct cgccgcccag cgagtgtccg accaggtaca cgggccggcc
    11401 cttcgccacg gcgccctcga ccaggtcgac caggtcgtcc accgattcct ggagggtgaa
    11461 cgggctgctg ctgcggcgct tgctcggtcc gtagcccgcg cggctgtagg tgatgatccc
    11521 gtagtcgctc tcctcgacca gcttgtccgt gatccagccg aagtgctcca tcgtggagat
    11581 cattccggtg ccgaagacca gcaccggaga gctgtcgtcc tccgagaccc gctcgttgta
    11641 gtgcagttcg ttgccatggc gggtggtgag cacccggccg tggggccagg ggtcggtggc
    11701 ccgcatgcgg cgcatcgcgg cgaggaatcc ggcgacggtc acgccgatcg cggccatgga
    11761 cgccgtggcc ttcagcatcc ggtcgtcgcg cccggccaca gcggggtggc tcttcggtgc
    11821 gctggtgtag gcgaccatcg ggtgcatcgc ctcgaaggcc gtgatgaagc ggcccagccc
    11881 catgaagtag ccgttggcca cgtggaacgc cgcggcgctc gccatgacgg gccgtgcgag
    11941 cattccgccc ttgaggtagg ccacagggaa gaggcactcc agggcgagca cgccgtgagc
    12001 gaggtaacgg gcggggacgg ggtagcggtt ggtgagtttc cacagcccct cgtgcccgta
    12061 cgtgcgggta cgcatgatgc cgttgagcgc ggagccgtca cgccagggct cgcccagcag
    12121 cttcacccag ccggagacca ggtaggagag gttcgcctgc agcgccacgt accacaacag
    12181 ggcgtcctgg acggccggtt gggacgagag gcgggcgaga ccggcggccg tctgcacgaa
    12241 cgaggagacc tggtccgagc cgtccgtgcc gtagcggtgg cgcggataga gagccgcgtt
    12301 gctcagtccg aggaacacgt tggcggcgcc gcgccagcgg gcgtttccgg gcgccagcag
    12361 ggccgcgctc gcagcgatgc gtgcgacgtg aagtgccttg gtggtcctgg gatttccgac
    12421 cgcatccaga aggcgccgtg tgggccgggt cgacgaggcg tgcattccgc gcgcgatcgt
    12481 ccagtcgttg aggccgccgc gccgtatctg ccgctggtgg gtgatgtatt cgaggctcga
    12541 cgtcagcgac gtcaccgccg tcagccgctc ggatatggcg agtgcacggc tgcgggagac
    12601 cggaacgggc ccgagaaatg tcgaggtcag ctttttggca agcgatttca cgtcggtctc
    12661 ctcggttccc gtgttccgga gcgggggtgg cggtcggagt gggggggtgg tggtctgaat
    12721 cgcgtgaaag atgtctggcg tggtgcgaag ttcaattggt tcgacaactg caaagaaaca
    12781 ggaaggagtt ggaaaagccc tggcagcggg ctgtgcgacg acttgaaaga aacattcaga
    12841 ggtgatggtg tgggacccgg ccggccggtg tcaggaccgg ccgaccgggc ggagccccga
    12901 tctcacaagg ccctgcagaa gggggtaccg cggggccgtg cgactagcgg gttcgagccg
    12961 ggatcagtcc tggcccgctt cgaaggccgc aaccgtcgcc gaggcgatgg cgacgccgcc
    13021 gaggaaggcg ccgggggtgc ccatcaccgg ggtgtagtcg gtgaagacga caccctcggc
    13081 gtcggtgatc gcgacagagg cgagctccgc cgactcgttg atctgcgaag tcacatcctt
    13141 catgtgtgca ctcctgttct gttctggacc ctccggagca cgcgtgtccc ccggggagca
    13201 agtggtcgac ggccggaccg agttggccgg ccggggatgg tgcctgtggt cagccgacgg
    13261 ccttgccggc cgcgtaggcg cccgtcacga cggccgcgcc gccgacgaag gcgcccgcga
    13321 gggcgggggt ggcgagaacc ggagctgctt cttcggcgat ctcgccctcg tgggcctcgt
    13381 gcagctggtc ctgaatttga agattcagct tctcttccag catgggattt cctccgagcc
    13441 tgtgagacat gactggctgt ttctcgcgaa agtggtcgaa gccaggtagc tcagggtggt
    13501 catcgggcgc ggagcccccg tcgattgagc tttcggtcgt caccgtaaac tgcagcgaag
    13561 cgggtctagc gcacgcttgc ctccccgtga atgcccaggt tcgcttccgc aggaatgaag
    13621 atgccagcac ggggtgcgcg gcagaagggg aatccgtgac agttttatgc aacgcgaagc
    13681 gtcatcttca tgccacggca gaaaatggcc tggaccatcg cgccgctggt cagagcctgt
    13741 ttacggtttg ccgctcagca agctcaagta aacctcaatc tttgagaatt gacacaagag
    13801 taagtaaccg aaagcgaaag atatccacct ccggaatgca tgtcctgtca tggcctgcca
    13861 cctcggaatg gtccgaattc gtccgggtgt gagggttgtt ggcggatccc ggccgtcccg
    13921 gtgccgcccc gcgcagcccg gcggtgtccc cggtgcatcg acgcgcaccg cggactccgg
    13981 gcgtggacgg cgcgtacaga ccgtagccgg gggcgagttg aggttcgcgg cgccggaccg
    14041 gagcacgttc cagggcccct cggtggaggc agttcgggcc ggggcgtcgg ccggtgcttc
    14101 ggtacggccg atacggacga tgcttcggta cggccggggc cccggactcg ccgctcagag
    14161 ccagccgcgc tcgcgtgcct tgcgcgccgc cgcgtgcctg ttctccgcgc ccagcttcgc
    14221 ggtcgcggcg gagagatagt tgcggacggt ccctggtgtg agggagacgc gctccgcgat
    14281 gtccgcgacg ggggcaccgc cggccgcaag ggccagcagt tccgtctcgc gggcggtcag
    14341 tggcgagtcg ccggtgctga tggcgtccgc cgccaactcg gggtccacat agcgggttcc
    14401 cccgtgcacg gcccggatga tctcggcgag ctgctgcgcg gaagcggtct tcggcacgaa
    14461 gccccgtacg cctgccgcga gcgcgcgctt gagatggccc ggcctggcgt gactcgtcac
    14521 gatcatcgtc cggcacgcgg gcagttcgtc gcgcagctgc gtcgcgacct gtacgccgtc
    14581 ggccccgggc atctgcagat ccagtacggc cacgtccggc gcgtgtgcgc gtgccatggc
    14641 gaccgcctcg gggccggagg ccgcctccgc gacgatggtg aggtcctcct ccagcgcgag
    14701 gagagcggtc agcgcgccgc ggatcagatg ctcgtcgtcg gcgagcagca cccggatgcc
    14761 gccgcccggc ccgccctcgt cgttccgccc gccctgcgcg ccgctcactc cgccgagtcc
    14821 ttcccgtccg tgccgctgcc gtgggtgccg gccgtgcctg ccgggtccgt gaccgcctcg
    14881 tccgcggtcg cgtcgttccc ggctgccagc gggacctcgg ccgtcagccg gaatgtaccg
    14941 ctctcgccgt cccgtgccac gcgcagcgtg ccgccgaccc cgtcgagacg ttcgcgcagc
    15001 cccgcgagcc cggagccggc gctccctccc ggggcctggc cgcgtgtgcc gtcgttctcc
    15061 atgaccagca gcgcgctgcg gcccgccggg tccgtgccca cccacaccgt gcaccaggtc
    15121 gcgtccgcgt gccgcagcac gttcgtcgcc ccctcccgca cgacccagcc gagcgcggcc
    15181 tgcacgggag ccggcagctg cgaaccgccg ttgtcggtac ggcagtcgac gccggcggcg
    15241 cgcaggatcc cgcgcgcgcc ggcgagttcg gtgggcaggt ccacgtcgcg gtagccgcgg
    15301 accaccgccc gcacctccga ctgagcctcg cgggcgatgc gctgcacctc ggtcatctgg
    15361 ccgacggagg cctcggtctc ggacccgcgc cgcaccagct gtgccgccag ctcgctcttg
    15421 agagcgatgg ccgacaggtt ccggcccatc acatcgtgca ggtccctgct gaagcgcagc
    15481 ctctcctcgg cgacggccag cctcgcctgt acgccgcggg cctcctccag ctccctgatg
    15541 acggcgatgt accaggcgga ggagcggccg gtgaagacgg acaggagacc gccgaggccc
    15601 acgacgacca gtgccgccag caggtccgcc ccgggcagcc ccgccgcggc gagagcggcc
    15661 gtcgtggcgg cgaggtagcc ggacagcgcg agcgccgccg tacgcctcgg caccgccaca
    15721 ccgaaggtga cggcgaacgg tgcgagcgcc ccgtgcagcc ccaggcccac ctccagcccg
    15781 acctcgaccg cgcggatcgc gacaagcacg accgtgaggg cggtcatcga ggccatcagc
    15841 acggccggca gcgcgagccg ggcatccgtg acggtgcgcg tgccgagata gctgtcgatg
    15901 gcccggtgca gcacgcccgt acagagcagg cactgcacca ggcccagccc gaggaccgtc
    15961 caggcgaggg tgcggggaag agcaccggga cccgcgttcg gcaccagctg cacgacgaag
    16021 cccacgagtg tcagccaggc gtacgcgacg agcatccacc gcgtcgacgc ctccacctgt
    16081 tcgtggctgc tgcgctcctg ccagcggcgg tacttcgggg ccacccccca ccagccgatc
    16141 acgggcccgt gctcctcacc ttctctagcg tcgcggctcc cagcggaacc agcgccgcac
    16201 ggcgacggtc ccgaggatga tccacaccac caggacggtc agcgccttca cggtgtccat
    16261 gccgctcagc gtgccgaccc agccgttgcg taccagctcc atcgtcggtg acaccgggag
    16321 cagagaacac acattggcga gcacgtccgg catgacgtcc agcgggacca cgactccgga
    16381 ccccacgaaa gagatcgcca tgaacgggaa tgtggtgatc tgcgaggctt ctgtcgtgcg
    16441 cgtgaaggcg gcggacaccg cggccagcag caccatcagc agcagcccca gcagcagacc
    16501 ggcggcgacg agctccggcc gctccggcgg cgcgaggtcg agcaggaccg caccgccgcc
    16561 gagcagcagg acgcactgcc cgagcgccag caccagggac ggcagcgcgc tgcccgtcag
    16621 gatctcgccg tcgctggcct caccggtgcg cagccgcttg agcaccagct cctcgcgacg
    16681 cgtgacgtag atgccggtca gattggcgta gacggcgaag accagcacgt agccgatcga
    16741 gcccgggacc agcaccgtcc ccagggaaag gcccgtgccc tccaggttca tgccgctggc
    16801 ggtctggcgc atcaggaccg tcagcagggc cggggtggcc agcgcgacga agagcatcgc
    16861 cttgttgcgc atcaggagcg tgagttcggc acgccccagc gcgcgcaggc ggctccacat
    16921 cgccgaagtg tccaccctgc ccggcgcctt gaccgtggcc gcgtccgtgc tgctcatacc
    16981 cgctccacct ccatgccgcc ggatgccgct cctgcccggt gcttgccggg tccgccggcc
    17041 tggctgtcct cgtccgcctc gtcgggaagc tgcgcgatct ccaggaacac ctcttcgagg
    17101 gtcgcggtgc gggcgtgcag ccccggcagt tcgacgcccg cctgccgcgc ccagatcagc
    17161 agatccgtca gcgccgactg cagctgcggc gtacggatct ccacacgtcc ctcccgcagg
    17221 gtgggctgcg gcagcgtcgt cggcagatgc gccggcgaga gtccgtcggg cagcgtgaag
    17281 cggatgctgg acggccgctc cgcgacgacc tgttcgggag tgccggtggt gacgatgcgt
    17341 cccgcacgca tgatggccag ccggtcggcc agctcctcgg cctcctccag gtagtgcgtg
    17401 gtcagcagta ccgtcgtgcc ggccctgcgc agctcacgca ccaagtccca ggtgtcccgg
    17461 cgcccttcgg ggtccatgcc ggtggtcggt tcgtccagga agagcacttc cgggtgcccg
    17521 acgagtgcca tcgccaggtc caggcgccgt cgttcaccgc cggagagctg tttcacccgg
    17581 acctgcgcgc gccggtcgga gagcccgacc tgcgccagca cctcgccgat cggacgggcg
    17641 tcgctggtgc agccggccca catccgtatg gtctcggtga ccgtcaactc ggagggaaaa
    17701 ccgccttcct ggagcatcac tccggtacgg ggccgcaccg cggtgcgctc cgagtacggg
    17761 tcgaagccga gcactctcac gttgccgccg ctgggccgtg ccaggccctc cagcagctcg
    17821 accgtggagg tctttcccgc tccgttcgtg cccagcagcg cgaagatctc gccctcccgt
    17881 acggagaacg agacaccgcg cacggcttcg aagcccttcg cgtatcgccg tttgagtccg
    17941 tcgacctcga tcgcatccat gtcctcagtt ttccgcgggc gcccgctgtc acccggtgcg
    18001 tgctgtcacg agtgcgcatg acgaacctca tgcgcgggca gggcggcttc acacggcggc
    18061 cgcgcgccgg tgggcgagag gcgcgcctgg agaacggtct ttcgggccgc ggatacgggg
    18121 cggccggatt ccggtccgga aacggaagga accccggtcc ggggaccggg gttctctcac
    18181 tgctgaatcg cggatcccgt ggaaccggat cccgatgagc ttggagcgga cgacgaggct
    18241 cgaactcgcg acctcaacct tggcaaggtt gcgctctacc aactgagcta cgtccgcgtg
    18301 cttccacccg acattcttcc cgacttcccg ggaggccctg ctgagtggtg cgcccccact
    18361 gtacctgatc gttaccgatg ccggtcctgt gagaacgaga gcgggtgaca ggaatcgcac
    18421 actgcgcctc ccccttggaa agggggcgct ctactactga gctacacccg cgcgctccgt
    18481 gaggtttccc tcgcggcgac gggcccgact ctagcggatc acccggggtc cgtggcaagt
    18541 cgggccgccc ggcccgcggt acgtgtgcgg cgcgtacgcc gcaagcgtgc cgcacgggcc
    18601 gggcacggag gtcaacggga ggcgttgaag gcgtcgtaga ccttcttcgg gatgcggccg
    18661 cgggcgggta cctcgaagcc gttggactcg gcccaggcgc gaacggcgcg cgggtcggga
    18721 gcgacggcgg tgcggtggta ggccttgccg gacttggccc gcttgcggcc cgcttcgacg
    18781 aagcgcgcga ggtcctcacg cagcttcttc gcgttctcga tgttgaggtc tacctcgtac
    18841 gacttcccgt cgagcccgaa ggagaccgtt tccgatgctt ctccgccgtc aagatcgtcg
    18901 gagagggtga ccactacacg ttgtgccacg gatatcggac cttccatcag gatcgcgaat
    18961 tggatcacag gattctccgc gctgacatgc aaggaccagg gggagctgcg agtgatccgc
    19021 aggattgagg tgggactttt cttttgtaca gctgtggact ttgcaatgtg aagcgagagt
    19081 atttcgactc gcgtgtcaga ccgcaatcgg gaccatactt ttttcacggc atttttccca
    19141 gagctccggc gggtgccgga accggcggag ggtcgtggaa agcgtgtgcg gcgagtgggc
    19201 ggggcagata tccacgcgcg tagattttcg tggccggtag gctggctggc gcgtcgcttc
    19261 gctggcagca cgcaccaacg ctcagcaaaa tcaccatcac cgggagtacc tgtggctcgc
    19321 gtcgtagtcg acgtcatgct gaagccggag atcctcgatc cgcagggaca ggcggtgcag
    19381 cgagcactgc cgcgtctcgg cttcgagggc atcgagggcg tacgccaggg caagcgcttc
    19441 gaactggagg tggcggagcc cgtcaccgac gaggcgctcg cccgtatcca cgaactggcg
    19501 gggactttcc tcgcgaacac agtgatcgag aactacacgg tgcgcgtcga agagggggcc
    19561 gctgcgtgag cggcggtctc ggacgcatcg gcgtcgtcac ctttcccgga tcactcgacg
    19621 acagcgacgc ccggcgcgcc gtgcgcctcg cgggcggcga gcccgtcgaa ctgtggcacc
    19681 gcgacaagga cctgcgtcag gtggacgcgg tcgtgctgcc gggcggcttc tcctacggcg
    19741 actatctgcg ctgcggtgcc atcgcccgct tctcgcccgt catggaaccc ctgctggagc
    19801 aggcacgcgc gggcatgccg gtgctcggga tctgcaacgg cttccaggtg ctgtgcgagt
    19861 cgcatctgct tccgggcgcg ctcacccgca acgaccacct gcacttcatc tgccgcgacc
    19921 agaagctgcg cgtcgagcgc acggacaccg cctggacgtc cgactacgcc gaaggccaga
    19981 agatcaccgt cccgctgaag aacggcgagg gcggttacgt ggccgacgag cacaccctcg
    20041 acgccctgga ggccgagggc cgcgtcgtct tccggtacct gaacggcaac cccaacggct
    20101 cccgccgcga catcgcgggc atctccaacg aggccgggaa cgtggtcggt ctcatgccgc
    20161 atcccgagca cgccgtcgag accctcaccg ggccgacgac cgacgggctg ggcttcttca
    20221 cctcggtact caagaggctg gtcaccgcat gactccgtcc gcgcagccca atcaccgcac
    20281 ggctctcgac accgtcaagc acgccaccga cacccccggc accgagcagc cgtgggccga
    20341 actcggcctc aagcaggacg agtacgagcg catccgtgag atcctcggcc gccgccccac
    20401 cggggccgag ctggccatgt actcggtgat gtggtcggag cactgctcgt acaagagcag
    20461 caaggtgcat ctgaagcagt tcggcgagaa ggcacccgag agcgacgcgc tgctcgtggg
    20521 catcggcgag aacgccggcg tcgtcgacat cggccaggac tacgccgtca ccttcaaggt
    20581 cgagtcgcac aaccacccca gctacgtcga gccctaccag ggcgcggcca ccggcatcgg
    20641 cggcatcgtg cgcgacatcc tcgcgatggg cgcccgtccc gtcgccgtga tggacccgct
    20701 gcgcttcggc gccgccg
//
