MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 43.0 89.1 190.0 6.05e-60
AEE65494.1 response_regulator BGC0000223.5 PKS:Type II 44.0 88.3 187.0 5.22e-59
ALJ99879.1 FlsR3 BGC0001904.2 PKS:Type II aromatic 43.0 88.3 186.0 1.05e-58
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 47.0 89.8 182.0 1.2e-56
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 46.0 89.8 177.0 6.36e-55
QCT05734.1 Tri1 BGC0001983.3 other:other 46.0 87.5 176.0 1.53e-54
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 45.0 88.7 174.0 4.88e-54
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 42.0 87.5 173.0 1.95e-53
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 44.0 92.6 170.0 3.61e-52
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 44.0 87.1 164.0 8.37e-50
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 44.0 90.2 161.0 6.1e-49
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 44.0 89.5 162.0 1e-48
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 38.0 90.2 161.0 1.25e-48
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 44.0 87.1 159.0 5.28e-48
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 44.0 87.1 159.0 5.28e-48
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 44.0 88.7 158.0 1.25e-47
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 42.0 89.8 157.0 3.85e-47
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 42.0 88.7 157.0 5.99e-47
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 44.0 82.0 155.0 1.67e-46
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 41.0 86.7 153.0 1.18e-45
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 36.0 87.9 151.0 6.74e-45
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 36.0 91.8 150.0 2.6e-44
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 41.0 87.5 149.0 4.05e-44
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 42.0 85.2 147.0 1.55e-43
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 34.0 87.9 147.0 3.65e-43
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 40.0 90.2 147.0 7.75e-43
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 42.0 87.9 145.0 1.02e-42
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 43.0 89.8 146.0 1.8e-42
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 40.0 86.7 147.0 3.84e-42
AFI57015.1 QmnRg3 BGC0000133.5 PKS 42.0 87.5 143.0 5.63e-42
AAK06808.1 putative_regulator_SimReg1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 39.0 96.1 143.0 1.74e-41
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 40.0 89.1 142.0 1.76e-41
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 38.0 91.0 142.0 1.92e-41
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 39.0 86.3 141.0 5.41e-41
ALJ99857.1 FlsR1 BGC0001904.2 PKS:Type II aromatic 43.0 82.0 140.0 5.97e-41
ABB69091.1 hypothetical_protein BGC0000260.3 PKS 35.0 89.8 141.0 9.94e-41
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 39.0 88.7 140.0 1.08e-40
AAL15604.1 Sim1 BGC0000270.5 PKS 38.0 96.1 140.0 1.36e-40
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 39.0 85.9 139.0 4.02e-40
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 38.0 87.5 137.0 3.21e-39
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 38.0 87.5 137.0 3.21e-39
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 35.0 87.5 136.0 5.05e-39
AVO00817.1 May18 BGC0001661.5 PKS 38.0 89.8 135.0 8.08e-39
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 40.0 87.9 135.0 9.75e-39
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 37.0 87.1 134.0 2.21e-38
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 37.0 87.5 134.0 8.1e-38
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 35.0 89.1 131.0 3.15e-37
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 37.0 86.3 132.0 3.49e-37
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 36.0 92.2 131.0 4.09e-37
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 41.0 86.7 130.0 5.77e-37
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 35.0 88.7 131.0 6.21e-37
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 37.0 86.3 130.0 3.02e-36
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 34.0 89.1 128.0 3.46e-36
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 37.0 88.3 128.0 3.85e-36
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 35.0 91.0 127.0 1.07e-35
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 33.0 87.9 126.0 1.92e-35
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 39.0 87.1 127.0 2.29e-35
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 40.0 86.7 125.0 3.51e-35
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 40.0 87.1 124.0 1.94e-34
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 33.0 86.3 121.0 1.66e-33
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 37.0 87.5 119.0 1.04e-32
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 37.0 87.5 119.0 1.04e-32
ADB02841.1 AzicR3 BGC0000202.5 PKS 35.0 89.5 119.0 2.21e-32
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 35.0 86.7 118.0 3.95e-32
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 34.0 88.7 117.0 4.9e-32
AEA29625.1 Por2 BGC0000409.5 NRPS:Type I 35.0 82.4 117.0 1.15e-31
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 38.0 90.2 112.0 7.98e-30
WP_082320004.1 response_regulator_transcription_factor BGC0002012.4 PKS 34.0 91.8 113.0 8.74e-30
QNL10611.1 Response_regulator BGC0002514.3 PKS 35.0 78.1 111.0 1.04e-29
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 34.0 86.7 110.0 2.88e-29
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 34.0 87.9 109.0 7.75e-29
QUS58949.1 response_regulator_transcription_factor BGC0002123.3 NRPS:Type I+PKS:Trans-AT type I 34.0 87.1 105.0 1.84e-27
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 29.0 88.7 105.0 4.65e-27
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 29.0 88.7 105.0 4.65e-27
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 28.0 89.5 104.0 8.32e-27
ASZ00168.1 putative_OmpR_family_two_component_response_regulator BGC0001785.5 PKS 36.0 73.4 103.0 1.47e-26
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 31.0 89.1 102.0 6.54e-26
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 28.0 88.3 101.0 1.23e-25
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 48.0 46.1 97.0 4.9e-25
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 43.0 44.1 96.0 1.53e-24
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 26.0 88.7 96.0 1.86e-23
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 38.0 57.0 84.0 1.25e-19
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 36.0 43.0 79.0 1.75e-16
BAW35603.1 putative_DNA-binding_response_regulator BGC0002357.3 PKS+other:other 36.0 46.1 74.0 1.88e-15
ABK32284.1 Jer4 BGC0000080.5 PKS 36.0 45.3 73.0 1.77e-14
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 38.0 44.1 73.0 2.16e-14
ABK32252.1 Amb4 BGC0000014.5 PKS 36.0 45.3 73.0 2.39e-14
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 38.0 46.9 70.0 4.92e-14
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 31.0 80.5 69.0 8.16e-14
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 33.0 48.0 69.0 1.66e-13
ADB02831.1 AzicR2 BGC0000202.5 PKS 28.0 78.9 68.0 2.52e-13
AWW87418.1 putative_LuxR_family_two-component_system_response_regulator BGC0001755.5 PKS 36.0 43.0 67.0 6.87e-13
ACN39724.1 SibA BGC0000428.5 NRPS:Type I 39.0 37.5 67.0 1.21e-12
AUA09456.1 Transcriptional_regulatory_protein_LiaR BGC0002291.3 PKS 33.0 44.9 65.0 3.42e-12
QDF63356.1 KyaR BGC0002346.3 ribosomal:RiPP 37.0 45.3 64.0 6.25e-12
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 36.0 46.1 64.0 7.23e-12
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 34.0 45.3 63.0 1.22e-11
ctg1_orf18 BGC0000053.5 PKS 31.0 47.3 63.0 1.24e-11
WP_030193597.1 response_regulator_transcription_factor BGC0002669.2 ribosomal:RiPP 31.0 64.8 62.0 2.91e-11
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 27.0 82.8 62.0 4.47e-11
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 38.0 46.9 61.0 1.26e-10
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 32.0 43.0 59.0 2.72e-10
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 31.0 63.7 58.0 7.41e-10
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 33.0 45.3 58.0 1.01e-09
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 33.0 46.1 57.0 1.35e-09
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 33.0 46.5 57.0 1.99e-09
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 32.0 46.1 56.0 3.66e-09
BCD33686.1 bacterial_regulatory_proteins,_luxR_family BGC0002448.2 NRPS:Type I 29.0 45.7 56.0 4.49e-09
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 28.0 84.8 56.0 7.7e-09
AAP03103.1 putative_2-component_system_response_regulator BGC0000874.5 other:other 28.0 91.0 55.0 8.77e-09
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 27.0 89.8 55.0 9.04e-09
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 30.0 46.5 53.0 5.51e-08
BBA21064.1 putative_two-component_response_regulator BGC0001740.5 NRPS:Type I+PKS 40.0 33.6 50.0 6.98e-08
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 29.0 46.9 52.0 7.34e-08
ARF06225.1 LuxR_family_transcriptional_regulator BGC0001593.5 NRPS:Type I 29.0 45.3 52.0 8.56e-08
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 29.0 46.9 52.0 9.95e-08
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 28.0 91.4 52.0 1.4e-07
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 27.0 82.8 52.0 1.4e-07
BBD82049.1 LuxR_family_transcriptional_regulator BGC0001920.4 ribosomal:RiPP 28.0 91.4 51.0 2.57e-07
ACI88882.1 AlnR5_two_component_response_regulator BGC0000195.5 PKS:Type II 28.0 62.9 50.0 3.8e-07
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 32.0 36.7 50.0 4.24e-07
ABD65961.1 two-component_system_response_regulator BGC0000341.5 NRPS:Type I 25.0 81.6 50.0 4.67e-07
AFL68048.1 response_regulator_with_CheY-like_receiver_domain_and_winged-helix_DNA-binding_domain BGC0001524.3 NRPS:Type I+PKS 32.0 39.5 50.0 5.99e-07
BAW27696.1 regulator BGC0001764.4 NRPS:Type I 28.0 44.1 50.0 6.31e-07
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 31.0 46.1 50.0 6.37e-07
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 30.0 46.9 50.0 6.52e-07
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 32.0 45.7 48.0 1.76e-06
MCG7203797.1 response_regulator_transcription_factor BGC0000248.5 PKS 29.0 45.3 48.0 1.76e-06
AKT74265.1 TxnRg4 BGC0002141.3 PKS 29.0 45.3 48.0 2.41e-06
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 29.0 48.4 48.0 2.74e-06
ACR33059.1 response_regulator BGC0000495.5 ribosomal:RiPP:Lanthipeptide 26.0 82.0 47.0 6.86e-06
AFW04580.1 transcriptional_regulator BGC0001783.5 other:other 31.0 46.9 46.0 8.37e-06