LOCUS       NZ_LDHL01000037        26444 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Bacillus mycoides strain G25-104 G25-104_contig000037, whole genome
            shotgun sequence.
ACCESSION   NZ_LDHL01000037
VERSION     NZ_LDHL01000037.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 446225)
  AUTHORS   Zheng,Z., Zheng,J., Zhang,Z., Peng,D. and Sun,M.
  TITLE     Nematicidal spore-forming Bacilli share similar virulence factors
            and mechanisms
  JOURNAL   Sci Rep 6, 31341 (2016)
   PUBMED   27539267
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 446225)
  AUTHORS   Zheng,Z. and Sun,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAY-2015) Microbiology, Institute of Life Sciences and
            Technology, Shizishan str., Wuhan, Hubei 430070, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 1.3.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 170.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015845385.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 01:09:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,771
            CDSs (total)                      :: 5,604
            Genes (coding)                    :: 5,404
            CDSs (with protein)               :: 5,404
            Genes (RNA)                       :: 167
            rRNAs                             :: 14, 16, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 16, 15 (5S, 16S, 23S)
            tRNAs                             :: 117
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 200
            CDSs (without protein)            :: 200
            Pseudo Genes (ambiguous residues) :: 0 of 200
            Pseudo Genes (frameshifted)       :: 85 of 200
            Pseudo Genes (incomplete)         :: 137 of 200
            Pseudo Genes (internal stop)      :: 43 of 200
            Pseudo Genes (multiple problems)  :: 53 of 200
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:34:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2982
            Orig. end                         :: 29426
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LDHL01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26444
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26444
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26444
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16444](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16444)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(148..273)
                     /locus_tag="ABD98_RS29080"
     CDS             complement(148..273)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128182.1"
                     /locus_tag="ABD98_RS29080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_255449116.1"
                     /transl_table=11
                     /translation="MIGYLRVFTLRDGREKAIIVEPWRLFKEEMNVLGIKDSDAF"
     gene            679..2094
                     /locus_tag="ABD98_RS26365"
                     /old_locus_tag="ABD98_25905"
     CDS             679..2094
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016127292.1"
                     /locus_tag="ABD98_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25905"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_002128184.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3e-45, bitscore:
                     149.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQAITVISTALTCFLLSNVGHAQEKPKQYYTVLLKDPSKFEQG
                     ITEIKKEHGEITYTVPEIGLIQFKGDTQISKNQSPLFESVNPSLQVEKPEVPHSIKMPN
                     LSTLSTKTLDTNLPPLWDMQWDMKEITHNGESYKKETGSHNVVVGIIDSGVDVDHPDLV
                     KNLIPGSKNFVPKGGLRGTEPEETGDINNINDINGHGTLVSGSIAANGELKGVAPDTGI
                     RAYRVFGNKSADAAWVINAIIEAAKDDVDVINLSLGSYYVNGKVYENGKLVDNGWAEVE
                     GYKRAIEYANQHGSVVVASAGNDSVNVANKQELNNFLKQKYEKEGKIFTGVGIEAPGEL
                     PGVVTVSSTGPTGQRSVFSNYGEGVIDISAPGGDYRLWQQYGEEVWWNTGLFRQEEVLT
                     TFNTGRYLFAAGTSMAVPKVSATLALIINHYNFKNQPKRSISHLYKNGIKKDIAPDKAS
                     WGNGQLDVYNAIK"
     misc_feature    715..730
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.16"
                     /tool="antismash"
     gene            complement(2105..3559)
                     /locus_tag="ABD98_RS26370"
                     /old_locus_tag="ABD98_25910"
     CDS             complement(2105..3559)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002185398.1"
                     /locus_tag="ABD98_RS26370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25910"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002128187.1"
                     /transl_table=11
                     /translation="MLKKLSLKNQFILTFAAVIFLSIVSTVCTLILIYSFLFIYNEKSV
                     LPANHYEKQVPSIEKFVEMNGDKIVDLSYQKKLEKVIPMQGITYQVMNTNGNRLYGTLS
                     DELLKNDKEVYHKINTSTQNGKLITKYIPIISNGKLVGVLAVRYILAASIDYYIEYVFI
                     IAFLVPFIFLTLYSYLLAKRLGKQLNKPIKEVIMASQKIKNKDLDFEIKYESENEIGIL
                     IDSFNSMKEELKNSLYVQWKLEQERRDMVASIAHDLRTPLTIILSHVEVLMEPMPNNQK
                     RIHHYLQTIKNNTERVLHLTEEMRRVSEVDNPDFTLMICNIAPAEMIPEMLEEFKELAE
                     NEDIQLTYTLLIKSEEKNLKFALDPNRLHQILTNIISNSIRFTPKKGRIDVQVEVKKDV
                     MSFSISDSGVGFNTKDIPFLFSKFYQGDLSRSNQLHHGLGLYIVEKLVKKHGGEIHAEN
                     NEIQGACISFTIHSLFSNEKRNYELS"
     gene            complement(3559..4239)
                     /locus_tag="ABD98_RS26375"
                     /old_locus_tag="ABD98_25915"
     CDS             complement(3559..4239)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014563.1"
                     /locus_tag="ABD98_RS26375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25915"
                     /product="response regulator transcription factor"
                     /protein_id="WP_001014563.1"
                     /transl_table=11
                     /translation="MNGTILVVDDESEIVDVLSDIFSDRDYKVLKAYNGEQALDHLKTQ
                     VDLVILDIMMPKMDGFEFCKVVREQIKCPILFLSAKHSEIDKVKGFTLGGDDYITKPFQ
                     VKELIARVEAHLRREKRERVNLQNQRFLGNLTINYSQHDVFIDGVKIDVTSKEFKILEL
                     LTVNLGQIFSKEQIYEKIWGLDAVGDLNTIIVHINNLRAKLSLGMSTYHIKTVWGVGYK
                     LEKC"
     gene            complement(4303..6150)
                     /locus_tag="ABD98_RS26380"
                     /old_locus_tag="ABD98_25920"
     CDS             complement(4303..6150)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128190.1"
                     /locus_tag="ABD98_RS26380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25920"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_002128190.1"
                     /transl_table=11
                     /translation="MSIFSLALKNITRNLSLYIVYLVSCILSVTIFYMYAAFLSYPKVS
                     GIEQLLIACEFIILLFSCFFISYSYDHFLTERKKEIGIWKTFGASKKQLFIIIVLENSI
                     IGAISILIGIMIGIVLSKSFFDFIGKSLFLSESFSYFFSPIATFFTVILFGVLFFFVSL
                     RSYYKIGRISVLELFQETRKPKDLPRFSKKKFIISLLILVISYVFILNASLPVLLFSFL
                     PVAALLLLGTYLFCSHGLVGTVSYLINKEKKHLNGIRMLIFISLRKKLYYNAKIIFLVS
                     ILLSMIMILISSIYLYSELNDQRMRNSHPQPAIFIVDKKQENTLESALEKNFKGEVEGF
                     HKKKWEGILLNSSKGEGKTFILQTDSFFIKDWTETKKDNLLFSKKNENIDKLHIQTNNG
                     NTELIVKNMVEKQAINSVSRIDNVAFVPADTFNELEKGSLPTQHVSFYTLDFKENNKGY
                     SALKKLFETLPLEIKEQSSVRLLHYENTVQLTSVLWIIALFIGFILLIALSSLLWFKLY
                     EDISNDRKIFHSLRKIGLNFNEIKKTLRVQIAIIFFVPIILGGINLFIAIYALQNILGG
                     IKIYSIILIFFIFLVFQLIFFFISNHYYYKKVVHEKNIN"
     gene            complement(6125..6904)
                     /locus_tag="ABD98_RS26385"
                     /old_locus_tag="ABD98_25925"
     CDS             complement(6125..6904)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128192.1"
                     /locus_tag="ABD98_RS26385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25925"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002128192.1"
                     /transl_table=11
                     /translation="MIMLEAKGIEKVYKTNFQEYPVLNNVNLTVHEGDFVGIMGPSGSG
                     KSTLLNVLSSLDFPSNGEITIKGQNLTNMNSDQLSNYRRENIGFIFQNYNLLDHLTIEE
                     NILLPAALRMGSKKGVRDKLETLVNELNIEPLLPKYPYEISGGQQQRAAIIRSLINDPY
                     LLFADEPTGNLDSKSAYDVLNILKTLNETHKSTILMVTHDSVAASFCNRVIFLKDGKIV
                     HEMQRSHEEKQFSFNQRILLYISKEVGENDVNIFTRT"
     gene            complement(6930..7688)
                     /locus_tag="ABD98_RS26390"
                     /old_locus_tag="ABD98_25930"
     CDS             complement(6930..7688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646187.1"
                     /locus_tag="ABD98_RS26390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25930"
                     /product="ABC transporter permease"
                     /protein_id="WP_002128193.1"
                     /transl_table=11
                     /translation="MKALVISEWERLWNQKKSKWMLGIFTVIVFLQAWFLKYYGVGIYN
                     DGQQVPLNSWNFSWFLLKESSFLITLIFMPVCFLNSLNVEYNSGAYRLFLIRPFQRLTF
                     LMSKWFSLSVMVLLYLFVVLFIGIVLGLVFFKADDAFTFYGQQKTSIEAIFYTVQVYGL
                     FFIIQMCGLAIASLISIIISNAVISFFLLIGIYIGCLYISQLSFFLLSVQSIFHALSTG
                     SNSLYVLILGIMIISVSVCISIWNKKEFTC"
     gene            complement(7708..8538)
                     /locus_tag="ABD98_RS26395"
                     /old_locus_tag="ABD98_25935"
     CDS             complement(7708..8538)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161130.1"
                     /locus_tag="ABD98_RS26395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25935"
                     /product="ABC transporter permease"
                     /protein_id="WP_002128195.1"
                     /transl_table=11
                     /translation="MRGLFISEFERLWTQKITWIILFFLPLMVVASVKYYLNWNQHTSP
                     GRPDYVTALNFPIISISEHLVVSFNIIAIILISTVIAHEVENGQLRMILIRPFSTSQLF
                     VAKLATILTTMFLYLTLFWIFNSIAGYLFFPKVDTLITFIDETKVSIAGAILYNLKYFF
                     ACFITMICIVSVFTLIGALSRSTMITLGSGVAFIFFAIAIPQILEFSSQTIISANTVLH
                     LMYMSIVKIQHTGIAFLLSSSNSINIYIVIVEAIYIFLFGMFAYLSFVKRDYFI"
     gene            complement(8535..9269)
                     /locus_tag="ABD98_RS26400"
                     /old_locus_tag="ABD98_25940"
     CDS             complement(8535..9269)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058380.1"
                     /locus_tag="ABD98_RS26400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25940"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_001058380.1"
                     /transl_table=11
                     /translation="MNNEIVLEANHLTKTVGGKTIVNDFSTKIYKGDICGFLGPNGAGK
                     TTVMRMFTGLIRPTKGVIKISGQDVNQNRQQALMNMGAIIESPIFFPYMTGRKMLQNLA
                     RLYPALSRKEQLEQVEAILSIVRLTDDADVKIKNYSLGMRQRLGIAQALLGDPDVILLD
                     EPANGLDPMGMRELRELILELREKKNLTFFISSHLLDEIQQMCDRLVIIRNGKLITQGR
                     KEELITDPTKRLEDVFVEMMTS"
     gene            complement(9367..9975)
                     /locus_tag="ABD98_RS26405"
                     /old_locus_tag="ABD98_25945"
     CDS             complement(9367..9975)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128197.1"
                     /locus_tag="ABD98_RS26405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25945"
                     /product="flavoprotein"
                     /protein_id="WP_002128197.1"
                     /sec_met_domain="Flavoprotein (E-value: 6.6e-34, bitscore:
                     111.4, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQMNQLLNSKKILVGVSGSIAVAGIFQYLAILKANFSEVKVIMT
                     KSAIKLIPAETVKLYCNEVFIDEELTLSGKPGHVELARWADLLMVLPATGNTISKVAHG
                     LADDLLSTVILAHDKPVLFFPNMNKLMWEKKVVQNNVKLLKEYDHIVIPPLKTTAFEIA
                     TMSLKPNYVLPNNQEVLHILFKEFEKRKSVTVHETVEMH"
     gene            complement(10001..11356)
                     /locus_tag="ABD98_RS26410"
                     /old_locus_tag="ABD98_25950"
     CDS             complement(10001..11356)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001177658.1"
                     /locus_tag="ABD98_RS26410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25950"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_002128198.1"
                     /sec_met_domain="LANC_like (E-value: 2e-72, bitscore:
                     238.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLTTEKKSFWLQGISIEKRNKALKLVRDIAEQLKDPMYVEKIVM
                     EPDNIPNGGTLHPWDPITLSHGYPGTIMLFAELDRQFPKEGWDLIAHSHLVEIQKAIEK
                     QGANSISMFGGVSGIAYATSYASRNYERYHIFLQKLNEFVLSQLHLVLNYGKEECGVHP
                     FMYDTIQGATGVGRYLLQNIQLESNLEALKQILNCFINMSNDIEVNGEVLPGWYVPYTN
                     QFLETDKILFPDGNFNCGHAHGMPGPLSLMALAIEQGIEVPGQKQAIRKMIDWLIKWQD
                     EGSWPARLSFKEVVNDQSYHVYPKRKGWCYGNPGVARALYLAGRSLKDQKAMKIALSSY
                     QDTLLQSEEEWDLSSPTFCHGRAGLLQMSIRMAKDEDGEISMQSITKLIDYVMDAYDPQ
                     APFGFKDLQSNEQTSNELNKVGLLEGVSGVLLTLLSLSAVEEPWWDGVFLIS"
     gene            complement(11374..13257)
                     /locus_tag="ABD98_RS26415"
                     /old_locus_tag="ABD98_25955"
     CDS             complement(11374..13257)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129903.1"
                     /locus_tag="ABD98_RS26415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25955"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002128199.1"
                     /transl_table=11
                     /translation="MKQILNHTPEDEKLSFSNILKSFHYWPGLFKLLWETHRGYFFCVL
                     TLNFVNGLLPAALILTIQYLVNTVQNIYQNGYKDDYFTHVLPFFIAFALVTILTGVTGS
                     VLETYKQLYRNLLSNKINVKLIEKAKRLPYSSFENPEIYNKLQRARQDSTYKPFAIFEE
                     LMGIIKSGITVISISGILMIWNWQFTLILILLPLISSWSIMKIGKEIFLISHKRAEETR
                     KQFYYYYLLTTDITVKEVKLFGLGNLLLKNYSNMFNRFYLQDRRLLLKKMRIDLFFQLI
                     SVAFVMFVQFMVVMDAVTGIIAIGSLIAYFQAVNTTQKTSNELMYMIFNMHQNNLYMTQ
                     LFSFLDVPEERDVSNNGDNTYLDSISFEEKGIRFINVSFKYPGQKEYTLKKVNFHIKPG
                     ETLALVGSNGSGKSTIVKLITKLYTDFEGIILLDGKPIHQYSTNEWQDKISAIFQDFVR
                     YELDVKDNIGYGDYKKADQVMAIQAAAKKSGALKMINSLPNQMDTQLGKTFANGIQLSG
                     GQWQRIAISRAYMRDASLYILDEPTAALDPEAEEEVFRDFKEITKNCMGLFISHRYSTV
                     RHATKIMVLDKGRVVELGTHNELLKIKGIYARLFELQAKNFIDYSKIQVNV"
     gene            complement(13229..16444)
                     /locus_tag="ABD98_RS26420"
                     /old_locus_tag="ABD98_25960"
     CDS             complement(13229..16444)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128200.1"
                     /locus_tag="ABD98_RS26420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25960"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_002128200.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.2e-172,
                     bitscore: 568.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.2e-27,
                     bitscore: 89.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4e-43, bitscore:
                     142.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITEKRKTIHTSNKTACNNIFEPLPFFMIRSPFLPFNALYQIKDQ
                     ELLIEKLREYAEMDYIKEAIAIASPSLLESLKYIHGDLSNRKTQQVISSVLRYMLRMTT
                     RPTPFGAFSGVASGEFKEKSLLEMSHFEQFKKRTRPDMEWLLGVVSSLEKNPCILQFLM
                     VSKNHATYRVGNRLYLPFSTECGQLRKKDMEKKENISITYSEVVKKVLDLAETHITVKE
                     LLQKLNNDYPGTDIKVMENFILQLVEQEYLITELRPPLTYDSPFDYVIDKLKVRVGEDQ
                     IWEDLLKVKDLILVYDQLQLGKGLSIYNDLILLMKGIYEVSTPLQVDFALNMHDLAIGK
                     NVANDVSKAAQVLWSIADSGVGFPHLQKYHIEFLEKYGTTREVPLVELLSEELGLGAPA
                     TYKNPKGNRDGENFTPPLDEERNVQLSYMLIEAIHNQQKEIEITDEIISRIGIEKDTRY
                     APDSFEVYGELYATSQEELDNGKYNLCLSPNPGSHAAGSTFGRFLDILDPNVRREIQQQ
                     EAEIDHQFNNDIVMVEGSFLPATGRSANVAIGKTTREVTVTLGTNGDEDTLQIPIDDIV
                     VGASLENFYLKSKKFGKRIKVVAGNVLNYQSGPNIYRFMREVSLNDLDHWRTFNWGNMT
                     SSPYYPRIRYKNIILSPAIWKLNRETIGMKNKPKSDDEFLILFEKWRVKWAVPRYVFMT
                     YSDNRILIDLENILHLRELKNELFKQGRLQLRESLHDINKNCLSSPLGSHAMEVVFPLK
                     KMNDVAKRKSLGAVEDGKKEMVSEKMIYRLPGSEWLYVKLYVPQARENEFISKYMTSFA
                     NNIVQNGLAQSWFFMRYRDPDAHIRLRFYGDPKKLNASVLTHLRDWANNLMNSGFIHKM
                     TIDTYEREIERYGGPYLIELAENFFHYDSRSVTMLLNVIGQQAELPVHALASLNIIEIM
                     ENFGLTYEQQLETIERNTDKYEFMDEFRPMRKLLNNIGNPEGDWNNLRNYNSSIGLEIY
                     KSLLVRRESLKEYFSSIQQYKNEDKLWNKQQTIMGAIIHMHCNRLLGANRELEKKALAF
                     TRHILSSQRYWRNQNETDTQSHT"
     aSDomain        complement(15668..15958)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_ABD98_RS26420_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.00E-28"
                     /identifier="RREFam001.1"
                     /label="ABD98_RS26420"
                     /locus_tag="ABD98_RS26420"
                     /protein_end="259"
                     /protein_start="162"
                     /score="89.9"
                     /tool="antismash"
                     /translation="MVSKNHATYRVGNRLYLPFSTECGQLRKKDMEKKENISITYSEVV
                     KKVLDLAETHITVKELLQKLNNDYPGTDIKVMENFILQLVEQEYLITELRPP"
     gene            complement(16531..16671)
                     /locus_tag="ABD98_RS26425"
                     /old_locus_tag="ABD98_25965"
     CDS             complement(16531..16671)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606628.1"
                     /locus_tag="ABD98_RS26425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25965"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_000606628.1"
                     /sec_met_domain="TIGR03731 (E-value: 1.1e-19, bitscore:
                     64.9, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 3.4e-09, bitscore:
                     31.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINEKNLFDLDVQVTTASGDVDPQITSISACTPGCGNTGSFNSFC
                     C"
     CDS_motif       complement(16600..16671)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MINEKNLFDLDVQVTTASGDVDPQ"
                     /locus_tag="ABD98_RS26425_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16531..16599)
                     /prepeptide="core"
                     /locus_tag="ABD98_RS26425_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="9.90"
                     /molecular_weight="1998.3"
                     /monoisotopic_mass="1996.9"
                     /core_sequence="ITSISACTPGCGNTGSFNSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MINEKNLFDLDVQVTTASGDVDPQ"
                     /leader_location="[16599:16671](-)"
                     /alternative_weights="2016.3"
                     /alternative_weights="2034.3"
                     /alternative_weights="2052.3"
     gene            complement(16721..16861)
                     /locus_tag="ABD98_RS26430"
                     /old_locus_tag="ABD98_25970"
     CDS             complement(16721..16861)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606628.1"
                     /locus_tag="ABD98_RS26430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25970"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_000606628.1"
                     /sec_met_domain="TIGR03731 (E-value: 1.1e-19, bitscore:
                     64.9, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 3.4e-09, bitscore:
                     31.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINEKNLFDLDVQVTTASGDVDPQITSISACTPGCGNTGSFNSFC
                     C"
     CDS_motif       complement(16790..16861)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MINEKNLFDLDVQVTTASGDVDPQ"
                     /locus_tag="ABD98_RS26430_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16721..16789)
                     /prepeptide="core"
                     /locus_tag="ABD98_RS26430_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="9.90"
                     /molecular_weight="1998.3"
                     /monoisotopic_mass="1996.9"
                     /core_sequence="ITSISACTPGCGNTGSFNSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MINEKNLFDLDVQVTTASGDVDPQ"
                     /leader_location="[16789:16861](-)"
                     /alternative_weights="2016.3"
                     /alternative_weights="2034.3"
                     /alternative_weights="2052.3"
     gene            17103..17276
                     /locus_tag="ABD98_RS26435"
     CDS             17103..17276
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030236.1"
                     /locus_tag="ABD98_RS26435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_001030236.1"
                     /transl_table=11
                     /translation="MNKAIWEFLMEMKKNKLTFETYELCPSLETLSVEERIVLDEYAKD
                     FRVKIDGGNQWV"
     misc_feature    complement(17147..17160)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.81"
                     /tool="antismash"
     gene            17251..18219
                     /locus_tag="ABD98_RS26440"
                     /old_locus_tag="ABD98_25975"
     CDS             17251..18219
                     /EC_number="4.2.3.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129906.1"
                     /locus_tag="ABD98_RS26440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25975"
                     /product="class 1 isoprenoid biosynthesis enzyme"
                     /protein_id="WP_002128202.1"
                     /transl_table=11
                     /translation="MMVEISGFKDCLINHIDYHISYRNQSDESEILLLIQKCLSHKGKV
                     LNPEYSGFSWGELYLALSFLTKRQPITKRELDKAMGVEFIFLSADIIDDLCDGDVLDPL
                     YFKNEYPRFLLVSQYLLMQGLIYLTYKTKDTATRDLLQQLIHSCCGEWKDIQFCFSIDK
                     KIILSEEEYMKLIEKKSGLLTEIIFRTINPENRILKEITSYIGIAGQLRNDANDAMTDN
                     KNDLQDLKAYLPFLKAYEYSCKTQDNFFENLTDEQISSSPEVRALVRDYIEQSGALHYC
                     RILSQLYYRKAFALLEMHFVLSKDEMTYFQMMVMGRGHSYA"
     gene            18212..20353
                     /locus_tag="ABD98_RS26445"
                     /old_locus_tag="ABD98_25980"
     CDS             18212..20353
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244598.1"
                     /locus_tag="ABD98_RS26445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25980"
                     /product="sensor histidine kinase"
                     /protein_id="WP_002128204.1"
                     /transl_table=11
                     /translation="MRNIWFCIPLSILYLLILLINNYYFHSSNFKESVNSLLISHFYMI
                     SVISLIFFTIGLISFLKKRQSIVAKKFFSLTSVFGIAILTSLLSSYDINIFKAIEVSSI
                     FILSYLLISFFSNFPVSTKPKYVKIFNLVSFVISTGLTIIYIIFCCFGYMSNNNFSFLF
                     KVLLITNLFLSISICVFLVSLHLRENNLKVKSQLYILIFGIILSFLPIVLLNLIPGLLF
                     GESKIPFTYCLPSIIIFPLTISYLLIKQEVIEFEIRISKWLTNLLFYLLNFLFLNFSVE
                     QFIDLSQKEIFILCGLSVLSVVLSVYIYKLILSLFRYLNIKKDAQSGLHKIELFQTLSK
                     EKHAKELAKLVGQLINQMFNINGISIIWNSNSIYHSLYETGIFQDMDKFELFNQLNQLE
                     QNYLLKEGTTPIHIQFEKYHLICFPILIYQGMQGAIIIGEKNDYTLFKPQEINELEEVV
                     INSANLLLSVNTLNSNKKEIRKAKVKAQNWKQFNYQIIQSLENERKRLSIFLHDEILQI
                     LILQLNEIRMLQTKRNFSIDILNSMDEQLEDIIYSIRKMCHNLHPIIVEDLGLEASLHT
                     LKREFELNYRILIHIQFNCKLKILSKNLEIQIYRIIKELLNNAIKHSKGTNVQIHIIEE
                     RGCYVCTVEDDGIGFCVPNSFSEFSTSNHLGLMTIQRQISELNGNLRISSEKEHGTLVT
                     FTIPVNWEENNEYTYTTSG"
     gene            20325..20933
                     /locus_tag="ABD98_RS26450"
                     /old_locus_tag="ABD98_25985"
     CDS             20325..20933
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128205.1"
                     /locus_tag="ABD98_RS26450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25985"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002128205.1"
                     /transl_table=11
                     /translation="MSIHTLLVDDHLLVMLGIQRLLESEEDIEVINTVHDPSILIKTVE
                     DTRPDVIVTDIRMKQYNGIELTKDLLSKFPDVKVVILSGYDHEEYYNAAFEAGASAYIT
                     KERSAFDLANAIRQSHMGYILFSKNQIMGNNIEALTSAEQRILLLISKDKTNYEISTDL
                     SISKRTVEYHISSIIRKLGVDSRVGAVVKGIKKGLIEGF"
     gene            complement(21352..22521)
                     /locus_tag="ABD98_RS26455"
                     /old_locus_tag="ABD98_25990"
     CDS             complement(21352..22521)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702509.1"
                     /locus_tag="ABD98_RS26455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25990"
                     /product="serine hydrolase"
                     /protein_id="WP_002131167.1"
                     /transl_table=11
                     /translation="MKTRSQITFASLALLIAGSSLLYTTPTSIVKAEPTQNVSSSLQTN
                     TQRDRNSVKQAMRDTLQLGYPGILAKTSEGGKTWGYAAGVADLSSKQPMKTDFRFRIGS
                     VTKTFIATVLLQLAGENRLNLDDSIEKWLPGVIQGNGYDAKQITIRQMLNHTSGIAEYS
                     RSKEADFTHTKRLYTAEELVKIGLSMPPDFAPGKGWSYSNTGYVLLGILIEKVTGNSYA
                     EEIENRIIEPLELSNTFLPGNSSVIPGTKHARGYVQPDGASELKDVTYFNPSIGSSAGD
                     MISTADDLNKFFFYLLGGKLMKEQQLKQMLTTVPTGRAEIGRYGLGIYETKLPNGVPIW
                     GHTGGIPGFSTFAGGILGGKHTLAVSLNSMGRANSPDPFKNILLAEFGK"
     gene            complement(23390..24820)
                     /locus_tag="ABD98_RS26460"
                     /old_locus_tag="ABD98_25995"
     CDS             complement(23390..24820)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055915.1"
                     /locus_tag="ABD98_RS26460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_25995"
                     /product="IS4 family transposase"
                     /protein_id="WP_197236388.1"
                     /transl_table=11
                     /translation="MNMNPTQELSLFAEELYQYMSPATLNQLAVEAGGMKRKRKCHGHH
                     FLSLCVWLNQQIATTSLTQLCSQLETSTGILLSPQGLNRRFNSASVAFFRTVFTTLLQA
                     KIGGLSKISHSLSAYFERIRILDSTTFQVPDRFASTYPGAGGCSHKAGVKIQLEYDLLS
                     GEFSDVKIEPGKRSDQAYGATRTGMIQKNELYIRDLGYFRLQDFKSIQDKQGYYLSRLK
                     LPTKIYRKEFKTVVFKTKPAQMKPVYIQIHLEDIMKQLQPGQVYELHDVYVGSKDKLPT
                     RIVVYRCTEEQKQKRLRDRAIREKKKGITYTERTKLLQGITVYMTNIPTEWVPKEKIYD
                     LYSLRWQIELLFKIWKSWFQIHRCKSIKQERLECHLYGQLISILLCSSTMFKMRELLLR
                     KKQKELSEYKAMYIIKDYFLLFHQALQKNTQELSKILLRLFNLLQHNGRKSHRYEKKTV
                     FDILGVVYEYTTSTHQVA"
     gene            complement(24930..25144)
                     /locus_tag="ABD98_RS26465"
                     /old_locus_tag="ABD98_26000"
                     /pseudo=""
     CDS             complement(24930..25144)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371402.1"
                     /locus_tag="ABD98_RS26465"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_26000"
                     /product="DUF3951 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDPLLMAVIGLPLTIVILVIIGFINYL"
     gene            complement(25352..26431)
                     /locus_tag="ABD98_RS26470"
                     /old_locus_tag="ABD98_26005"
     CDS             complement(25352..26431)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832858.1"
                     /locus_tag="ABD98_RS26470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABD98_26005"
                     /product="Ger(x)C family spore germination protein"
                     /protein_id="WP_002128209.1"
                     /transl_table=11
                     /translation="MKQWVFFLIFSVLLTGCAKTKIVDDIDLIQVASYDLEAEDKIRGT
                     FAISAYTSSGGGQTKIYSALGKSSKEILARASEKSSGPLELGQLRVIIFDKKLAKKGMQ
                     EILETMNRNPSIGNSIYLAIANENGGTLLKGNYSKEKGVSTYLSSLIEQNVKNGVQPET
                     NFYLFLNQLYDDARDSYLPLISKKENLLELTGVVLFKRYRMVDTLSFKDLFIFKVLTDK
                     FRGGTYQFRLPGFSDNYATIENIKSETKYKMKGNSQNPFIDAHIQVKGEIQELTKTKNL
                     DNAKEIRKLEKIMENEIEKKATKLIKRFINKGTDPIGLRKFGRTQTRKWNDKEWENSYK
                     HFRFHVTANVKIIQSGVTE"
ORIGIN
        1 cgtgtctttg aatattcata attacacctc cattttattc gtatataaca tgtgcgtaat
       61 tatgatattt atacataaca cgattcattt ctgtctcata ttctgtctag taaattgctt
      121 ttctttttta tactcgatta gatgaattta gaacgcatcc gaatctttga ttcctaaaac
      181 attcatttct tctttaaata aacgccatgg ctctactatt attgcttttt cacgaccatc
      241 ccttaaggtg aaaactctta aatatccaat catacactct cctaaatatt taaattcaca
      301 tttcattttt attgctattg ctatacatat ttataacctt caaatacaaa aacaataagt
      361 tccctactga ataaagacct aaatacagat accccctatt tactttagga tactttttaa
      421 atttcattca ctcattagaa caaaaaattg atggcttctc caccaaaaga attatgcttc
      481 tgtttttaaa gtaactccaa agaaagtaat attgcgctaa ataccactta tatgtacggt
      541 atatacagat ttgaaattcc gaatgatttg ttaccttatt tataggatct aagtggaatt
      601 ataaagtggg caatagggcc ttgttctgcg gttcatcttc aaattctacc tccaatttat
      661 aaaagtaagg ggataattat gaaaaaacaa gcaatcactg tcatttcaac cgcgttaacg
      721 tgttttttac tttctaatgt aggacatgct caggaaaaac ctaagcaata ttacaccgtt
      781 ttattaaaag acccatcaaa atttgagcaa ggcatcactg agataaaaaa ggagcatgga
      841 gaaattactt atactgtccc ggagatagga ctcattcaat tcaaaggaga tacacaaatt
      901 tctaaaaatc aatctccctt atttgaatca gttaatcctt ctttgcaagt cgaaaaacca
      961 gaggttcctc attccataaa aatgcctaat ttatcaactc tttcaacaaa aacattagat
     1021 acaaacctac ctcccttatg ggatatgcaa tgggacatga aggaaattac tcataatgga
     1081 gaaagttata aaaaagaaac tggctctcat aatgtggttg ttggaattat tgattcggga
     1141 gtcgatgtgg atcatcctga cttagtaaaa aatcttattc ctggatctaa aaacttcgtt
     1201 ccaaagggag gattgagagg tactgaacct gaagagacag gtgatattaa taatataaat
     1261 gatatcaatg gccatggaac tctcgtttca ggatctattg ctgcaaatgg ggaattaaaa
     1321 ggcgtggctc ctgatacggg aatcagagca tatcgtgtat ttggaaataa atcagctgat
     1381 gcagcctggg tcattaatgc catcatcgaa gcagctaagg atgatgtaga tgttatcaac
     1441 cttagtcttg gttcctatta tgtaaatgga aaagtctatg aaaatggaaa acttgtagac
     1501 aatggatggg cagaagtaga aggttacaaa cgtgctatag aatatgccaa tcagcatggt
     1561 agtgtagtag tagcttctgc aggaaatgat tctgtaaacg tggctaataa acaggagcta
     1621 aataactttc ttaaacaaaa atatgaaaaa gaggggaaaa tatttactgg tgtaggaata
     1681 gaagcacctg gggaattacc aggtgtagta acagtatcat caaccggtcc aaccggacaa
     1741 cgttctgtat tctctaatta tggagaaggg gtcattgaca tatctgctcc aggaggagat
     1801 tatcgtttat ggcaacaata tggcgaagag gtatggtgga atactggtct tttccgacaa
     1861 gaggaagtac tgacaacttt taatactgga agatacttat ttgccgctgg tacatcaatg
     1921 gcagttccga aagtatccgc tacactagct ctaattatca atcactataa ttttaaaaat
     1981 caaccgaaaa gatcaatttc acacctttac aaaaacggaa taaagaaaga tatagcacct
     2041 gataaagcct cttgggggaa cggacagctg gacgtatata atgctattaa ataatgaaaa
     2101 ggaactatga caattcatag ttcctttttt cgttactaaa aagagaatgt atcgtgaatg
     2161 aaatgcatgc cccttgaatc tcattatttt cagcatgaat ttctccaccg tgttttttaa
     2221 ccaatttttc cacgatatac aaaccaagtc catgatgtag ttgatttgac cttgaaaggt
     2281 caccttggta gaatttacta aataaaaacg gaatatcttt tgtattaaat ccaactccag
     2341 aatccgagat agaaaaagac ataacgtctt ttttcacctc cacttgcaca tcaattcttc
     2401 ctttttttgg agtaaaacga atgctattag aaataatatt cgtaagaatt tgatgcaaac
     2461 gattcggatc aagtgcaaac ttaagatttt tttcttctga tttaataagt aaagtatagg
     2521 ttaattgtat atcttcattt tctgccaatt ccttaaactc ttcaagcatt tctggaatca
     2581 tttcagctgg agctatattg caaatcataa gagtgaaatc agggttgtcc acttcagaga
     2641 ctctcctcat ttcttctgtt aaatgcaata ctctttctgt attattctta attgtttgca
     2701 agtagtgatg aatccgtttt tgattatttg gcatgggttc cattaatact tctacatgag
     2761 acaaaataat agttaacggt gttcgcaaat catgtgcaat ggaagcaacc atatcccgac
     2821 gttcctgttc taatttccat tgaacataca atgaattttt taattcttcc ttcatactat
     2881 tgaaagaatc aattaatata cctatttcat tttcactttc atattttatt tcaaagtcta
     2941 aatccttgtt tttaattttt tgtgaggcca ttattacctc tttgataggt ttattcaact
     3001 gttttcctaa acgcttagct aataaataag aataaagcgt taaaaatata aaaggaacaa
     3061 gaaaagcaat aataaataca tattctatgt aataatcaat agatgcagct aatatgtatc
     3121 gtacagcaag cacaccaact agtttaccat tacttataat tggaatgtat tttgtaatta
     3181 gtttaccatt ttgagtagat gtatttattt tatgatacac ttctttatca tttttcaata
     3241 attcatcgct caatgtacca tataatctat ttccattcgt attcataact tgataagtaa
     3301 ttccttgcat tggaatcact ttctctagtt ttttttgata ggataaatct actattttat
     3361 ccccattcat ttctacaaat ttttcaatgc tgggcacttg tttttcataa tggttggcag
     3421 gtaaaacaga tttttcatta taaataaaaa gaaaagagta tattaaaatt aacgtacaaa
     3481 ccgtactgac aatacttaaa aatattacag ctgcaaatgt tagaataaat tggtttttca
     3541 acgataattt ttttaacatt aacatttctc caacttatag ccaactcccc atacggtttt
     3601 aatatggtaa gttgacatac ctaaacttaa cttagctctt aagttattaa tatgtactat
     3661 tattgtattg agatccccaa ctgcatccag cccccaaatt ttttcataaa tttgttcctt
     3721 agaaaagatt tgtcctagat ttaccgttaa aagctctaat attttaaact ctttactcgt
     3781 tacatctatt tttactccat caatgaaaac atcatgctgt gaatagttaa tggtcaagtt
     3841 tcctaagaaa cgttgatttt gcaagtttac acgttctctt ttctcacgcc tcaagtgggc
     3901 ctcaacacgt gcaattagct ccttaacttg gaatggtttt gtaatatagt catctccacc
     3961 taaagtaaag ccttttactt tatctatttc tgaatgttta gcactcaaaa atagaatcgg
     4021 gcattttatt tgttcacgaa cgaccttaca aaattcaaaa ccgtccattt taggcatcat
     4081 aatatctaaa atgactaaat caacttgtgt ttttaaatga tctagcgctt gttctccatt
     4141 gtaggccttg agaactttat aatcacgatc agagaatata tcagagagta catctacaat
     4201 ttctgactca tcatctacaa caagaatcgt tccattcata aaaaaacact cctttctagt
     4261 ttagattaaa aatcttatta ttttgtaaaa tatattttct tgttaattaa tattcttttc
     4321 atgaacaact tttttatagt aatagtggtt tgaaatgaag aaaaatatta attggaagac
     4381 taagaaaata aaaaatatta atattattga gtaaatttta attcctccca atatattttg
     4441 caaggcgtag attgctataa atagatttat cccccccaga ataattggta caaagaaaat
     4501 tatagcaatt tgaaccctta atgttttttt tatttcattg aaattcaaac cgatttttct
     4561 taaagagtga aatatttttc tatcattaga tatatcttca tataacttaa accaaagaag
     4621 actggataaa gcaattaaca agataaaacc gataaataat gctattatcc ataaaactga
     4681 agttaattga actgtatttt cataatgtag aagacgaaca ctggactgtt cctttatctc
     4741 taaagggagt gtctcaaata atttttttag tgcactataa cccttattat tttccttgaa
     4801 atctaatgtg taaaatgaaa catgttgagt aggtaatgat cccttctcta attcattaaa
     4861 agtatctgct ggtacaaaag ctacattatc tatccgagat accgagttaa tcgcctgttt
     4921 ttcgaccata ttttttacta tcaattctgt attaccgtta tttgtttgga tatgcaactt
     4981 atcgatattc tcattttttt tactaaataa caggttatct ttttttgttt ctgtccagtc
     5041 ctttataaag aatgaatctg tttgtagtat aaaggtttta ccttctccct ttgatgaatt
     5101 cagtaatata ccttcccatt ttttcttatg aaatccctca acctctcctt tgaagttttt
     5161 ctctaaagca gattctagtg tattctcttg ttttttatca acaataaata tagctggctg
     5221 tgggtggcta tttcgcattc tttgatcatt caactctgaa tataaatata tggagctgat
     5281 taatatcatt atcattgata agagtattga aacaaggaag ataattttag cattataata
     5341 aagttttttc cttagactta taaatattag cattcgaatg ccatttaaat gctttttttc
     5401 tttattgatt aaataggata cagttcctac taatccgtgc gaacaaaaaa ggtacgttcc
     5461 taataataaa agagcagcta caggtagaaa agagaataat agtacgggta aagatgcatt
     5521 aaggataaaa acataagaaa taaccaaaat taacagggaa ataatgaatt tcttctttga
     5581 aaacctaggt aaatcctttg gttttcttgt ctcttgaaat aattccaaaa cagaaatgcg
     5641 tccgatttta taataactac gcaatgaaac aaaaaagaac agaactccaa acaaaataac
     5701 tgtaaaaaag gtagcaattg gagagaagaa ataggaaaat gactcgctta agaagagaga
     5761 tttcccgatg aaatcaaaaa agcttttgga tagtactata ccaatcataa tcccaattaa
     5821 gatagaaatt gctccaatta tcgaattttc taaaactatg ataataaata attgtttttt
     5881 tgaagctccg aatgttttcc aaataccaat ttcctttttc cgttcagtaa gaaaatggtc
     5941 ataagaatat gaaatgaaaa agcatgaaaa tagcaagatg atgaattcac acgcaattaa
     6001 cagttgctct attccagaaa cttttggata tgaaagaaat gctgcgtaca tataaaaaat
     6061 tgtaactgat agaatacaac ttacaagata cactatatac agtgaaagat tgcgagttat
     6121 atttttaagt gcgagtgaaa atattgacat cattctcccc cacttcctta gagatataga
     6181 gtagtatacg ttgattgaaa ctgaattgct tttcttcatg ggaacgttgc atctcatgaa
     6241 caatcttgcc atctttcaaa aatatgaccc tgttgcaaaa actagcagct acagagtcgt
     6301 gagttaccat taagattgtt gatttatgtg tttcattcaa tgtttttagt atattcaata
     6361 catcataagc agattttgaa tctagatttc ccgtcggttc atcagcaaat aacagataag
     6421 gatcgttaat taacgaacga ataatagcag ctctttgctg ttgtccccca gagatttcat
     6481 agggatactt tggcaaaagc ggttcaatat ttagttcatt cactaatgtt tcgagtttat
     6541 ccctaacacc ctttttgctc cccattctta aagctgcggg tagaagaata ttttcttcaa
     6601 ttgttaagtg atctaacaaa ttgtaatttt gaaaaataaa accaatattt tcgcgacgat
     6661 aattgcttaa ttgatcacta ttcatattag ttaaattctg tcccttaatt gtaatttctc
     6721 catttgaagg aaaatcaaga gaggaaagca catttaaaag tgtagacttt ccactccctg
     6781 aaggtcccat aatccctaca aaatctcctt catgaacagt taagttgaca ttatttaaaa
     6841 ctggatattc ttggaaatta gttttgtaaa ctttctcaat tcctttagct tctaacataa
     6901 tcatggtaaa cctcccttct atccttttat taacatgtaa attctttttt attccaaatg
     6961 cttatacaaa cgctaacact aataatcatg atacctagaa tcaggacgta taaactgtta
     7021 cttcctgtgc tgagagcatg gaagatactt tgaacggata ataaaaagaa cgataactga
     7081 cttatgtaca agcagccgat gtaaattcca atcagaagga aaaagctaat aactgcattt
     7141 gaaattatga tacttattaa actagcaata gctaaaccac acatttgaat aataaaaaac
     7201 aatccatata cttgtaccgt atagaatatt gcttctatag aggtcttttg ttgaccgtag
     7261 aaagtaaaag catcatctgc tttaaaaaac accaacccaa gtactatgcc aataaaaaga
     7321 acaacaaata agtagagtaa taccattaca gaaagagaaa accattttga cataagaaag
     7381 gttaatcgtt gaaaaggcct aattaaaaat agacgatatg ctcctgagtt gtattctaca
     7441 tttaagctat tcaagaaaca tacaggcatg aaaatcaaag taattaagaa agaagattcc
     7501 tttaataaaa accatgaaaa attccaagaa tttagtggca cttgttgccc atcattataa
     7561 atcccaaccc catagtactt caaaaaccaa gcttgaagaa aaacaataac agtaaaaatc
     7621 cccaacatcc atttactttt tttctgattc catagtcgtt cccattcact tataactaat
     7681 gctttcaatt gaactccctc ctagttttca aataaaataa tctcttttca caaatgacaa
     7741 gtatgcgaac attccaaata agaaaatata aatcgcttcc actataacaa tgtaaatgtt
     7801 tatactatta cttgatgaaa gtagaaatgc tatacctgta tgctgaattt taacgattga
     7861 catgtacata agatgtagta cagtattagc gctaattatc gtttggctag agaattctaa
     7921 aatctgtgga attgcaatag caaagaaaat aaaggccacc cctgatccaa gagtgatcat
     7981 cgtacttcta cttaacgccc ctattaatgt aaatacagaa acaatacaaa tcatagtaat
     8041 gaaacatgca aagaaatact ttaagttata taatatcgcc cctgcaatag aaaccttggt
     8101 ttcatctata aatgttatta atgtatctac ttttggaaag aataaatagc ctgctatgga
     8161 attaaaaatc caaaacaaag ttaaatatag gaacatggta gttaatatag tagcaagctt
     8221 agctacaaaa agttgtgagg tagaaaatgg acgaatcaaa atcattctta attgtccatt
     8281 ttctacttca tgcgctataa cagtagaaat cagtattata gcgataatat taaacgaaac
     8341 cacaagatgc tcagaaatac ttattatagg aaaatttaaa gcagtaacgt aatctggtct
     8401 tccaggagaa gtatgttgat tccagtttag ataatattta actgacgcaa ctaccattaa
     8461 aggtaagaaa aacaagatta tccaagttat tttttgcgtc caaagccttt caaattcaga
     8521 aataaaaagc cccctcatga tgtcatcatc tccacaaaca catcttccaa cctttttgtt
     8581 ggatctgtaa ttaactcttc tttccttcct tgggtgataa gctttccatt tctaattatg
     8641 acaaggcggt cacacatttg ctgaatttca tctagtaaat ggcttgaaat aaaaaaggtt
     8701 aaatttttct tttcacgaag ttcaagaatt aattccctta gctctctcat gcccatagga
     8761 tccagaccat tggctggctc atctaataaa ataacatctg gatcacctag aagagcttgt
     8821 gcaatcccga gtcgctgtct cattcctaat gaataatttt taattttcac atctgcatcg
     8881 tcagttaacc ttacaataga tagtattgct tctacttgtt ccaattgttc ttttcgagaa
     8941 agagcagggt ataatctcgc taaattttgt agcatttttc tacccgtcat atacgggaag
     9001 aatattggtg attcgataat tgcgcccata ttcatcaaag cctgttgtct attttgattt
     9061 acatcttgac cacttatttt tatgactcct tttgtcgggc gaattaatcc tgtaaacata
     9121 cgcataacag ttgtttttcc tgccccattc ggccccagaa aaccacaaat atctccttta
     9181 tatattttag ttgaaaaatc atttactatt gtcttgccac ctacagtttt tgttaagtga
     9241 tttgcttcta aaactatttc attattcata taaaatccct ccttatggac taatatagaa
     9301 gacaaatatt aaaaaaaaat aaagaaaaga ataaagaaaa gaaaaaaact cacaaaaatg
     9361 tgagttttag tgcatttcaa ccgtttcatg tacagttact gactttcttt tctcaaattc
     9421 cttaaagagt atatgcaata cttcttgatt attaggtaaa acatagttcg gtttcaaaga
     9481 catagtcgca atttcaaaag ctgttgtttt caaaggcgga atcactatat gatcatattc
     9541 ttttaaaagt ttaacattat tctgaactac ttttttctcc cacattaatt tgttcatatt
     9601 aggaaaaaag agaactggtt tatcatgagc aagaatgact gtacttaata aatcatcagc
     9661 taaaccatga gctacttttg aaatagtatt tcctgtagct ggtaatacca ttagtaagtc
     9721 tgcccatcta gccaattcca catgacctgg tttaccactt agggtaagtt cctcgtcgat
     9781 aaatacctca ttacaatata atttcacggt ttctgcaggg ataagtttta ttgcactttt
     9841 tgtcatgata acctttactt cactaaaatt cgctttcaat atagctaaat attgaaaaat
     9901 tccagctact gcaatagagc cgcttactcc tactaatatt ttcttagaat taagcaattg
     9961 attcatttgg ttcatactgt aacatcctct caattcttga ttaggaaatt agaaatactc
    10021 cgtcccacca tggttcctct actgcgctta gacttaataa tgttaaaagt acaccactta
    10081 caccttccaa tagtcctacc ttgtttagct cgtttgaagt ctgctcattg gattgtaagt
    10141 ctttaaagcc aaatggtgct tgaggatcat atgcatccat tacataatct attaattttg
    10201 taatggattg catcgatatt tccccatctt catcttttgc catcctaata gacatttgta
    10261 ataatcccgc tcttccatga caaaatgttg gagaagataa atcccattct tcctcacttt
    10321 gcaaaagtgt atcttgataa gaacttaatg caattttcat ggccttctga tccttcaagg
    10381 atctcccagc cagatagaga gctcttgcta ctcctggatt tccatagcac cagccttttc
    10441 gcttcggata cacgtggtat gattggtcat tgaccacttc tttaaaacta agcctcgcag
    10501 gccacgaacc ttcatcttgc cattttatta gccaatctat cattttacga atcgcttgct
    10561 tttgtccagg aacttcaatt ccttgttcga tagccaacgc catcaaggaa agtgggccag
    10621 gcattccatg agcatggccg caattgaaat tcccatccgg aaatagtatc ttatctgttt
    10681 ccaaaaactg attggtgtac ggtacgtacc aaccaggtag aacttctcca ttcacctcaa
    10741 tgtcattaga catattaata aaacaattga gaatttgttt gagtgcttcc aaatttgatt
    10801 caagttgaat attttgcagt aaataacgcc ctactccagt agcaccttgg attgtatcgt
    10861 acataaatgg atgaacacca cattcttctt tcccgtagtt caatacaaga tgtaactgcg
    10921 aaagtacaaa ttcatttaac ttttgtaaaa atatatgata tctttcatag ttacgcgaag
    10981 catacgatgt cgcatacgca ataccagaaa caccgccaaa catagaaata ctattcgcac
    11041 cttgtttttc tattgccttt tgtatttcta ccaagtgact atgtgcaata agatcccatc
    11101 cctcttttgg aaactgtcga tctaattctg caaataacat tatagtacct ggataaccat
    11161 gggataaagt aatggggtcc catggatgaa gtgttcctcc atttggtata ttatcaggct
    11221 ccataacaat tttttctaca tacatcggat cctttaattg ctctgctata tcacgaacta
    11281 actttaatgc tttatttctt ttttcaatac taattccctg taaccaaaat gacttttttt
    11341 ctgtagttaa ttgcatattt ttctcctctc taattaaaca ttcacttgaa ttttggaata
    11401 atctataaaa tttttagctt gtaactcaaa tagtcttgcg tatattcctt ttatctttaa
    11461 tagttcatta tgagtaccta gttccacgac tctaccttta tcgaggacca taatttttgt
    11521 agcatgcctt acagttgaat accgatggga tataaagagc cccatacaat tctttgtaat
    11581 ttctttaaaa tctctaaaaa cctcttcttc tgcttctgga tctaatgcgg cagtaggttc
    11641 atctagaata tataggctcg catccctcat gtatgctctt gaaatggcga ttctttgcca
    11701 ttgccctcca gataactgaa ttccgttcgc aaaagttttc ccaagttgtg tatccatttg
    11761 gttaggcaaa ctattaatca tctttaatgc tccagatttt ttagcagcag cttgtatagc
    11821 cattacttga tcggcttttt tatagtcacc atagccaata ttatctttaa catctagttc
    11881 atatctaaca aagtcttgga aaatagcact aatcttatcc tgccattcgt ttgtactgta
    11941 ttgatgaatg ggttttccat ctaatagaat aatcccttca aagtccgtat aaagttttgt
    12001 aattaacttt acaatcgtag atttacccga accattagat ccgacaagag ccaatgtttc
    12061 acctggtttt atgtgaaaat tcactttttt taacgtatac tctttttgac caggatactt
    12121 aaaagagaca tttataaatc gaataccttt ttcctcaaaa gagatgctat ctaaataagt
    12181 attgtctcca ttatttgaaa catccctttc ttcaggaacg tccaaaaatg agaatagttg
    12241 agtcatataa agattgtttt ggtgcatatt aaaaatcata tacattaatt cattagatgt
    12301 tttttgtgta gtatttacag cttgaaaata agcgataaga cttccaatag caataatccc
    12361 tgttacagca tccataacca ccataaactg cacaaacatt acaaaagcca cgctgattaa
    12421 ttgaaaaaac aggtcaatcc tcatcttttt taaaagcaga cgtctatctt gcagataaaa
    12481 tcgattgaac atatttgaat aattttttag aagtaaattg cccaatccaa ataatttcac
    12541 ttcttttact gtgatgtctg tcgttagcaa atagtagtag taaaattgtt ttcttgtttc
    12601 ttcggcacgc ttatgactaa ttaaaaaaat ttcttttcca attttcatga ttgaccagga
    12661 agagattagt ggtaatagaa ttaaaattag ggtaaactgc cagttccaaa tcattaagat
    12721 accggaaata gaaatcacag ttattccact ttttataatc cccataagtt cttcaaaaat
    12781 agcaaatggt ttatatgtgg aatcttggcg cgccctttga agtttgttgt aaatttctgg
    12841 gttctcgaaa ctggaataag gtaatctttt tgctttttct attaatttta cattgatttt
    12901 attagaaaga agatttcggt aaagctgttt atatgtttcc aaaactgatc ctgtaacacc
    12961 cgttaaaatt gtaactagtg caaaggctat aaaaaacggt aaaacatgag taaaataatc
    13021 atccttgtac ccattctggt agatgttttg tactgtatta acaaggtatt ggattgtcaa
    13081 aatcaatgct gcaggtaata atccatttac aaaatttaag gtaagcacac agaagaaata
    13141 tcctctgtgc gtttcccata aaagtttaaa taaaccaggc caataatgaa aagactttaa
    13201 aatatttgaa aatgatagtt tctcatcttc aggtgtgtga ttgagtatct gtttcattct
    13261 gattcctcca atatcgctgg cttgataaga tatgccgcgt aaaggcaagt gctttttttt
    13321 ctagttcccg attagctccc aatagtcgat tacaatgcat atgaataatt gctcccataa
    13381 ttgtttgttg tttattccag agcttgtctt catttttata ttgttgaata ctggaaaaat
    13441 attcttttaa tgattctctc cgaactaata gacttttata aatctctagt ccaattgatg
    13501 aattgtaatt acgtaaatta ttccaatcac cttcaggatt tccaatgtta tttaataatt
    13561 ttctcattgg tctaaattca tccatgaatt catatttatc agtatttctt tcaatagttt
    13621 ccaattgttg ttcataagtt aaaccaaaat tctccataat ctcaattatg tttaaggatg
    13681 ccagtgcatg tactggcagt tcagcttgtt gtccgatcac attaagaagc attgttactg
    13741 acctactatc gtaatggaag aaattctcgg ccaattctat cagatacgga ccaccatatc
    13801 gctctatttc tcgttcatac gtatcaatcg tcattttatg aataaatcca gagttcatta
    13861 aattatttgc ccaatccctt aaatgagtaa gaacagatgc attcaacttc ttgggatctc
    13921 cataaaatcg caaacgaata tgagcatctg gatcacgata tcgcatgaag aaccatgatt
    13981 gagccaaacc attttgtaca atattattag caaatgatgt catatatttt gaaataaatt
    14041 cattctctct tgcttgtgga acatagagct taacatatag ccattcactt ccgggcaaac
    14101 gataaatcat tttctcacta accatctctt tttttccgtc ttcaacagct cctaaactct
    14161 tccttttagc gacatcgttc atttttttca acggaaatac aacttccatt gcatgactac
    14221 ccagcgggct gctaaggcaa tttttattga tgtcatgtaa tgattctctc aactgtaatc
    14281 taccctgctt aaaaagttca ttctttaatt ctcgaagatg aagaatattt tcaagatcaa
    14341 ttaaaatcct attgtcacta tacgtcataa atacatagcg tggaacagcc catttcactc
    14401 tccatttttc aaataggatt aaaaattcat catcactttt aggtttattt ttcataccaa
    14461 tagtttctct atttaacttc caaattgcag gagacagaat gatatttttg taacgaatcc
    14521 ttggataata aggtgaagat gtcatattac cccaattgaa tgttctccag tggtctaaat
    14581 catttaggga aacttctctc ataaagcgat aaatattagg gccactttgg taatttagta
    14641 cattaccagc taccacttta attcttttcc caaatttttt agatttcaga taaaagtttt
    14701 ctaatgatgc tccaacgaca atatcatcaa ttggaatttg caaagtatct tcatctccat
    14761 ttgttccaag agttacagtt acttctcttg tagtttttcc aattgccaca ttcgctgaac
    14821 ggccagttgc cggaagaaaa cttccctcta ccataacgat atcattatta aattgatggt
    14881 caatctccgc ttcttgttgc tgaatttcac gtctaacatt tggatctaag atatctaaaa
    14941 atcgaccaaa tgtgcttcct gctgcatgag atcctggatt tgggcttagg cataaattat
    15001 actttccatt gtctaattcc tcttgcgaag tagcatacaa ttctccatat acttcaaatg
    15061 aatctggagc gtatcgagta tctttttcta ttccaattct gctaattatt tcatcagtaa
    15121 tttcaatttc tttttgctga ttatgaatag cttcaataag catatatgat aattggacat
    15181 tacgttcttc atctaaaggc ggcgtaaaat tttctccatc cctatttcct tttggatttt
    15241 tatatgtcgc gggtgctcca agccctaatt cctcacttaa aagttctacc aatggaactt
    15301 ccctagttgt tccgtatttt tctaaaaatt caatatgata tttttggaga tgaggaaatc
    15361 caactccgct atcggctatg ctccataaca cttgagctgc tttactaaca tcatttgcta
    15421 cgttttttcc tatagctaaa tcatgcatat ttaaagcgaa atctacttga agaggcgttg
    15481 aaacttcata aatccccttc attaatagga taagatcgtt gtatatagaa agcccctttc
    15541 caagctgtaa ttggtcataa acaagtatta aatcttttac cttcagtaaa tcttcccata
    15601 tttgatcttc accaactctt acttttaact tgtcaatcac ataatcaaat ggggagtcat
    15661 atgtaagtgg cggtcttagc tcagttataa ggtattcttg ctctaccaac tggagaataa
    15721 agttttccat tacctttata tctgtgcctg gatagtcatt attcaacttt tggagaagct
    15781 ctttcactgt aatatgtgtt tcagctaaat ctaaaacttt cttaacaact tcactatatg
    15841 taattgaaat attttctttt ttctccatat ctttcttgcg aagttgtcca cattcagttg
    15901 aaaaaggtaa atataggcgg tttccgacac gataagtagc atgattttta ctaaccatta
    15961 aaaattggag aatacaagga tttttttcaa gtgatgaaac cactcccaat aaccattcca
    16021 tatcaggccg agttcttttc ttaaattgtt caaaatggct catttcaagt aaagattttt
    16081 ctttaaactc tccggatgct accccggaaa aagctccaaa aggtgttggg cgtgttgtca
    16141 ttcttaacat atatcgtaat acagaagata ttacttgttg tgttttccta ttacttaaat
    16201 caccatgtat atatttaaga gattcaagca atgaaggact tgcaatggca atggcttcct
    16261 taatgtaatc catttctgca tattccctta atttttcaat caataattct tgatccttaa
    16321 tttgatatag tgcgttaaat ggtaaaaacg gggatctaat cataaaaaat ggtagaggtt
    16381 caaatatatt attacatgcg gttttatttg atgtatgaat agtcttcctt ttttctgtaa
    16441 tcatttggaa tcttcccttc tgttctaatc aaatattata ataggagaaa aagagggaca
    16501 catctgtgtt ccctcttttt tggcattcaa ttagcaacag aagctattga atgaacctgt
    16561 gtttccacag ccaggcgtac aagctgaaat acttgtaatt tgtggatcta catcacctga
    16621 agctgttgtt acttgaacat ccaaatcaaa aaggtttttt tcgttaatca ttttcttttc
    16681 cccctaaagt ttttttaaga caatatgtct tatgtagcaa ttagcaacag aagctattga
    16741 atgaacctgt gtttccacag ccaggcgtac aagctgaaat acttgtaatt tgtggatcta
    16801 catcacctga agctgttgtt acttgaacat ccaaatcaaa aaggtttttt tcgttaatca
    16861 ttttcttttc cccctaaaat ttttattaag acgttatgtc ttatgtgtct aatttatcag
    16921 ataaatatcc tagtagaatc cgtatattcc gcaagtttat attgtaaatt cacgcataat
    16981 aaaaaaaata tatgtaaatt aagtattaaa aatttaagga ctatattgaa aatatcccat
    17041 ttttattgta ttttttttat atagaactaa aatacagaat atttggaaag agggttattt
    17101 ttatgaataa agcaatatgg gaatttttaa tggagatgaa aaaaaacaaa cttacctttg
    17161 aaacttatga attatgtcct tcattggaga cactatcagt tgaagagcga attgtattag
    17221 atgagtatgc aaaggatttc cgggtgaaaa ttgatggtgg aaatcagtgg gtttaaagat
    17281 tgtttaatca atcatattga ttaccatatc tcctaccgta atcaaagtga tgaatctgaa
    17341 atacttctac ttattcagaa atgtctttct cataaaggaa aggttttaaa tcctgaatat
    17401 tctggcttct cgtggggaga gctatatcta gctctttctt ttttgaccaa acgacaacca
    17461 ataacaaaaa gagaattaga taaggcaatg ggggttgaat ttatcttttt atcagcggat
    17521 ataatagatg atttgtgtga tggagacgta ttagatccat tatattttaa aaacgaatat
    17581 cctcgttttt tgttagtttc tcaatattta cttatgcaag gactgatata cttaacttat
    17641 aagacaaaag atactgcaac acgagatctt ctccaacaat tgatacattc gtgttgtgga
    17701 gaatggaaag atatccaatt ttgtttttca atagataaaa aaataatttt aagtgaagaa
    17761 gaatatatga aacttattga aaagaaatcc ggtctactca cagaaattat ctttcgaact
    17821 attaatcctg aaaatagaat tttaaaagaa attacatctt atatagggat agctggtcag
    17881 ctaagaaatg atgctaatga tgccatgaca gataataaaa atgaccttca ggacttaaag
    17941 gcttatcttc cttttttaaa agcttatgaa tatagttgca aaacacagga taattttttt
    18001 gaaaatttaa cggatgaaca aatatcttcg tcacctgaag ttcgggcatt agtccgggat
    18061 tacatagaac aatctggagc acttcactat tgtcgtatcc tatctcaact atattataga
    18121 aaagcatttg cactcttaga aatgcatttt gttctttcta aagacgaaat gacttatttt
    18181 caaatgatgg ttatgggcag aggtcactcc tatgcgtaat atttggttct gtataccttt
    18241 aagcatttta tatttattaa tacttttaat aaataattac tattttcact ctagtaattt
    18301 taaagaaagc gttaactctt tattaattag tcatttttat atgatcagcg ttattagtct
    18361 tatttttttt actataggat taattagctt tttaaaaaaa agacaatcta ttgtagcaaa
    18421 aaaattcttt tctctaacat cagtctttgg gatagctatt ttaacatcct tattatctag
    18481 ctatgatata aatattttta aagctataga ggtgagtagt atttttatac tttcttatct
    18541 cttaataagt tttttctcta atttccctgt atctaccaaa ccaaaatatg taaaaatatt
    18601 caaccttgta tcatttgtaa tttcaacagg attgacaatt atttatataa ttttttgttg
    18661 ttttggatat atgtctaaca ataattttag ctttttattt aaagttttac taattactaa
    18721 cctatttctg agtattagca tctgtgtttt tcttgtttca ttacatttac gagaaaataa
    18781 ccttaaggtg aaaagtcaat tatatattct gatttttggt attattctta gttttttacc
    18841 tattgttcta cttaatctga ttcccggtct actttttggg gaatctaaaa ttccatttac
    18901 atattgttta cctagtatta ttatatttcc tttaactatt tcttatttat taataaagca
    18961 agaagttatc gaatttgaga ttagaatttc taaatggcta acaaacttac tcttttactt
    19021 gctcaatttc ttatttttaa atttttcggt tgagcaattc atagatttgt cacaaaaaga
    19081 aatatttata ctatgcggct taagtgtatt atctgttgta ctctctgtat atatatataa
    19141 acttattctc tcattattta ggtatttaaa cataaaaaag gatgcacaat caggtttaca
    19201 taagattgag ctttttcaaa cactctcgaa ggaaaaacat gctaaagagc ttgcaaaatt
    19261 agtcggacag cttattaacc agatgtttaa cattaacggt atttccataa tatggaactc
    19321 aaatagtatt tatcattcat tatatgagac aggtattttt caggatatgg ataagtttga
    19381 gctgtttaac caattgaatc aacttgaaca gaattactta ctaaaggaag gtactactcc
    19441 tattcatatt cagtttgaaa aataccactt aatttgtttt ccaatactca tttaccaagg
    19501 catgcaggga gctattatta ttggtgaaaa aaatgattat acattattta aacctcaaga
    19561 aattaatgaa cttgaagagg ttgtaataaa ctcggcaaat ttactattaa gtgttaatac
    19621 cctcaatagt aataaaaaag aaattcgaaa agcaaaggta aaagctcaaa actggaaaca
    19681 atttaactat cagattattc aatctctaga gaatgaaagg aaaaggcttt cgattttctt
    19741 acatgatgaa attcttcaaa ttcttatttt gcaattaaac gaaataagaa tgcttcagac
    19801 caaaagaaac ttttctatag acatattaaa ttcaatggat gagcaacttg aagatattat
    19861 ctatagcatt agaaaaatgt gtcataatct tcaccctatt atcgtagaag atttaggttt
    19921 agaagcaagt ttacacacac taaaacgcga gttcgaatta aattatcgca ttctcattca
    19981 tatacaattt aattgcaaat taaaaattct ctcgaaaaat ctcgaaatac agatttatcg
    20041 tattataaaa gagctactga ataatgctat taagcactcc aaggggacta atgttcaaat
    20101 acatatcata gaagaaagag gctgctatgt ttgtactgta gaagatgacg gcataggctt
    20161 ttgtgttccg aacagttttt ctgaatttag tacaagcaac caccttggtc taatgaccat
    20221 ccagcgtcaa atttccgagt tgaacggaaa tttgagaata tcttctgaaa aagaacatgg
    20281 aacattagtc acatttacca taccagtaaa ttgggaggaa aataatgagt atacatacac
    20341 tactagtgga tgaccatttg ttggttatgc taggcatcca aagactacta gaatctgagg
    20401 aagatattga ggtgattaat accgttcacg atccttccat attaattaaa actgtggaag
    20461 atacccgtcc tgatgtaatt gttacagaca tcaggatgaa gcagtataat ggtattgaac
    20521 ttacaaaaga tttattgtca aaatttccgg atgtaaaggt tgtaattcta tcaggatatg
    20581 atcatgaaga atattataat gcggcctttg aagctggagc aagtgcatac attacgaaag
    20641 aaagatcagc atttgaccta gctaacgcaa ttcgtcaaag tcacatggga tatatactat
    20701 tttctaagaa tcagattatg ggaaataata ttgaagcact aacttctgct gaacaaagaa
    20761 tattactctt aatctcaaaa gataaaacaa attatgagat tagtacggac ctttcaatca
    20821 gtaaaagaac tgtagaatat cacatttctt caattattag aaaactgggt gtagattcaa
    20881 gagttggagc agtcgtaaaa gggattaaaa aaggattaat tgaaggtttt taaggataag
    20941 gggacattgc agaactgtta tgtctaaaag tttattgata aatacagaga cacagaatca
    21001 tactatataa ccaccaatac ctgcaaatga agaaatagga ctcatgattg ggtcctattt
    21061 cttcatttga gataacttta accagataaa aattacaatc ttttattata ttcataaatt
    21121 ccctccccat tatattttaa attcattctg tatatgttcc caccacattt ctctcaggct
    21181 ggaaaagcaa aatcttgctc aaaatgaaaa cacgccaccc tttcctatga ttctacagaa
    21241 agaatagcgt atttttttat tttagggagg attttatttt attagcttaa tagcgctgga
    21301 ttaccgtcaa agttccaaaa acctcaaaat ttatccgttt ttccttttta cctacttacc
    21361 aaattcagca agtaaaatat ttttaaaagg atcaggactg ttagctctac ccatactgtt
    21421 caaactgacg gccaacgtat gcttacctcc aagtatacct ccagcaaaag tactaaatcc
    21481 tggaatacca cctgtgtgtc cccatatcgg gacaccgttt ggaagcttag tttcatagat
    21541 tccaagaccg tatctcccga tttcagctct tcctgtagga actgtagtaa gcatttgttt
    21601 tagttgctgt tctttcatta attttccacc gagcaagtaa aaaaagaatt tgtttaagtc
    21661 gtcagcagta gaaatcatat ctccagccga gctacctata cttggattaa aataagtaac
    21721 gtcttttagc tcacttgctc cgtctggttg gacatatcca cgggcatgct tagtgcctgg
    21781 aataacgctt gaattgccag gtagaaatgt attcgacaat tcaagcggtt caataatccg
    21841 attttcaatc tcttccgcat aactgtttcc ggttactttt tcaataagga tacccagtaa
    21901 tacgtatcct gtgtttgaat aagaccagcc ctttcctggg gcaaagtctg ggggcatcga
    21961 aagtccaatc ttcactagct cttcagcggt atacaatctt tttgtatgcg taaaatcagc
    22021 ttcttttgac cttgagtatt cagcgatacc acttgtatga ttcaacatct gacggatagt
    22081 aatctgttta gcatcatatc catttccttg aatgacacca ggcaaccatt tttcgatgga
    22141 gtcgtctaga ttcaggcggt tctctccagc taattgaagt aaaaccgttg cgatgaacgt
    22201 cttcgtcaca ctgccaatgc gaaagcgaaa atctgttttc attggttgct tgctgctcag
    22261 atccgctacc ccagcggcat aaccccaagt ttttccaccc tcggaagttt tagcaagtat
    22321 ccccgggtat ccaagttgca atgtatcccg cattgcttgc ttgacggaat tacgatctcg
    22381 ttgagtattt gtttgtaacg aactagatac attttgagtg ggctctgctt ttacaattga
    22441 ggttggcgtt gtgtataaca gggaacttcc agctattaaa agagccagac ttgcaaatgt
    22501 aatttgacta cgtgttttca taaggcattc ctctcctcta ttcatattgt ataggtggtt
    22561 gcttgatatt tcatactcac cacacagcta tcatctctac cgatgacaaa aagtcaacat
    22621 tgaattcgta atcatcttca taatgattat ttttacaagc tccattctgt cctaggtaaa
    22681 cccctctttt cccacatata tgttaacccc caaaattact tcttttcctt gaaacactct
    22741 tgttactggt ttgtttttca tatataagtc atatctgttc cgcctttcac gcctctttat
    22801 attttcatca tacacaatga aaatctcttt tttcttacct atttcttaca aattacttac
    22861 gttcaaaata gcttctataa taggatgaag gagtatctgt accggaaagt tcagtaaata
    22921 tattaatcaa aaagaaacac agaggttttt cacctctgtg tttctttttt ccatcctttt
    22981 aaatattaaa agtcgattta ctcttaacag gatgaattct ggctcttttt taatgtaatt
    23041 tttcttcttg caatacaaca caaatgacat tgtgctgcat gaaacactcc taacgttgtt
    23101 aaaatcaatt gtttttaagt cgaaattcat taaatatcca tcaacctaac agaacagatt
    23161 gcccaaaaac gataaaaatg aactttgtat ctataaaaaa cacaaaattt tcgtttaaga
    23221 ggaacttcaa aatcttaact tgataggcat gtggcgagac cccacatcca tcaacttaaa
    23281 gtatattttt atacaaaata cggtctttcc acgtagtttt ttattatttg ttatagattt
    23341 tataaaagta ggcatatcaa ataaaccctg acgggtttca atttttttac tatgctacct
    23401 gatgagtaga agtggtatac tcataaacaa cacccaaaat atcaaagact gtctttttct
    23461 cgtatcgatg agattttcgt ccgttgtgct gtaggaggtt aaacaggcga aggagaatct
    23521 ttgataactc ttgggtgttc ttctgtaatg cttggtgaaa aagtaaaaaa taatccttaa
    23581 ttatgtacat cgctttatat tcacttagct ctttctgttt cttacgtaac aggagttctc
    23641 tcattttaaa catagtagaa gaacataata ggatactaat gagttgtcca taaaggtgac
    23701 attctaaccg ttcttgttta atagatttac aacgatgaat ttgaaaccaa gatttccata
    23761 ttttaaataa cagctcaatt tgccaacgca gtgaatataa atcatagatt ttctcttttg
    23821 gtacccattc cgtaggaata tttgtcatat ataccgtaat tccttgtaaa agcttcgtac
    23881 gctctgtata tgtaatccct tttttctttt cgcgaatagc tcgatcacgt aagcgtttct
    23941 gtttttgctc ctccgtacat ctataaacca caatacgagt aggcagtttg tctttactcc
    24001 ctacatatac atcatgtaac tcatacactt ggccaggttg taattgtttc atgatatctt
    24061 ccaaatgaat ttgtatatat accggtttca tttgagcggg ttttgtttta aataccactg
    24121 ttttaaattc ttttctatat attttagttg gtaatttaag acgtgataaa taatatcctt
    24181 gtttatcttg gatagactta aagtcttgta aacgaaaata tcctaagtca cgaatatata
    24241 gttcattctt ttgtatcatg cctgtgcgag tcgcaccata cgcctgatca cttcgttttc
    24301 ctggttcaat ttttacatca gaaaattctc cactcaacaa gtcatactct agttgaattt
    24361 tcacaccagc tttatgacta catcctccgg caccaggata agtagatgcg aatcgatctg
    24421 gaacttgaaa ggttgtagaa tcaaggatac gaatgcgctc aaagtaagca gaaagagaat
    24481 gagaaatctt agataatcct ccaattttag cttgtagaag tgtagtaaat acagttcgaa
    24541 agaaggctac agaagcagag ttaaatcttc gattaagtcc ctgaggactt aataaaattc
    24601 cagttgaagt ttctaattga ctacaaagtt gagtaagaga ggtagtagcg atttgttgat
    24661 ttagccatac acataaagat aaaaaatggt gcccatggca cttgcgtttt cgtttcattc
    24721 cgccagcttc tacagctaat tgattaagtg tagcaggaga catatattga tataactctt
    24781 cagcaaataa agacaactct tgcgttggat tcatattcat aaaaagcacg tcaccctttc
    24841 ttattaacat aagagaatag taacgtgttt ttaattttta gaatagttca tattattaaa
    24901 ctgatggatg tgccttgtga taagtaatgt tattttttct tcttcccatc accatcttca
    24961 ccttcagcta ctagtacttt ctgttcttca tgaaattccg aaatcgtttg accagtcatg
    25021 tgatcaaatg gagtataaaa agaagtgata tttttctttt ttacaaataa tttataaaac
    25081 caattataac taatattact attgttaacg gtagtcctat aacagccata agcagtggat
    25141 ccatagaaaa tatgtatttc tatatagaaa tacatatttt cattcggttt atactctatt
    25201 ataaaactaa aaaaaggggt acagctgtac atgtataaaa attattaaat ataaaaagca
    25261 tctcaacttt tcatgagatg cttttttcct gttttcatcc cataacacct tgtttcattt
    25321 attaaaagtt ttcatacctt atgtgacttt tttattccgt cacaccagac tggataatct
    25381 tcacattcgc agttacatga aaacggaaat gcttatagga attttcccac tctttatcgt
    25441 tccactttct tgtttgagtc ctaccaaatt ttctaagacc tataggatct gtccctttat
    25501 taataaatct ttttattaat ttagttgcct ttttctctat ttcattttcc attatcttct
    25561 ctagctttcg tatttctttg gcattatcta agttttttgt ttttgtcagt tcttgtattt
    25621 cacccttcac ttgaatatga gcgtctatga atggattctg gctatttccc ttcattttgt
    25681 attttgtttc agatttaata ttttctatcg tggcataatt atcagaaaaa ccaggaagac
    25741 ggaactgata cgttccacct cgaaatttat cggtcaacac tttgaatata aacaaatctt
    25801 taaatgagag cgtatcaacc atcctatacc ttttaaataa aaccacacca gttaactcta
    25861 ataaattttc tttttttgaa attagaggca aatatgaatc tctcgcatca tcataaagtt
    25921 gatttaaaaa taaataaaaa tttgtttctg gttgtactcc attcttaaca ttttgctcaa
    25981 ttaaggaaga taaatacgtg gaaacccctt tttctttaga gtaatttccc tttaaaagcg
    26041 tccctccatt ttcatttgca atcgctaaat agattgaatt tccgatactt gggtttcggt
    26101 tcatagtttc taaaatttct tgcattccct ttttagctaa ttttttatca aatataatca
    26161 cacgtaattg acctaactct agaggtccag aagatttttc agatgctctt gccaaaattt
    26221 ctttactact cttccccaat gctgaataaa tttttgtttg tccaccgcca ctacttgtat
    26281 atgccgaaat cgcaaacgtt cctcttattt tatcttcagc ctctaaatca tatgaagcaa
    26341 cttgaattaa atcgatgtca tcaacaattt tagttttagc acaccctgtt aagaggacac
    26401 tgaatatgag aaaaaatacc cactgtttca tctttatctc ctta
//
