LOCUS       NZ_CP059991            26455 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces gardneri strain ATCC 15439 chromosome, complete genome.
ACCESSION   NZ_CP059991
VERSION     NZ_CP059991.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces gardneri
  ORGANISM  Streptomyces gardneri
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Genome-scale analysis on the transcription unit architecture of
            Streptomyces venezuelae ATCC 15439
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Biological Sciences, KAIST, 291 Daehak-ro,
            Yuseong-gu, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 6.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP013129
            Genome Coverage                   :: 187.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015710995.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 17:12:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,199
            CDSs (total)                      :: 8,101
            Genes (coding)                    :: 7,918
            CDSs (with protein)               :: 7,918
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 70 of 184
            Pseudo Genes (incomplete)         :: 147 of 184
            Pseudo Genes (internal stop)      :: 16 of 184
            Pseudo Genes (multiple problems)  :: 48 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:23:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7568829
            Orig. end                         :: 7595284
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059991.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26455
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /region_number="28"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..26455
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..11431
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11431
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6431](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6431
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    841..856
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
     gene            complement(2561..2890)
                     /db_xref="GeneID:95693679"
                     /locus_tag="H4W23_RS34175"
                     /old_locus_tag="H4W23_34160"
     CDS             complement(2561..2890)
                     /codon_start=1
                     /db_xref="GeneID:95693679"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34160"
                     /product="hypothetical protein"
                     /protein_id="WP_152335203.1"
                     /transl_table=11
                     /translation="MPDTPGSRHYVSRGVDVRITAENDEIELRLDDTPIAVAYLDGEYH
                     SQLANQFTGFPTMDALVDSLLETEGKTWTLHGGTSGGAHPHGAPNGGHGTGHGGHHGHE
                     GGGDR"
     gene            3439..3786
                     /db_xref="GeneID:95693680"
                     /locus_tag="H4W23_RS34180"
     CDS             3439..3786
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693680"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /locus_tag="H4W23_RS34180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS30 family transposase"
                     /protein_id="WP_230883339.1"
                     /transl_table=11
                     /translation="MPDGLKAEQVAPHLTRTLLGIPPQLRRTLTWHRVREMAEHHAITA
                     ETGMPIYLCKPRSPWQRGTNENTNRLLRQYLPKGADLRTFSQADLDAIAHELNHRPSQD
                     PRLPHSGRCLR"
     gene            3908..4539
                     /db_xref="GeneID:95693681"
                     /locus_tag="H4W23_RS34185"
                     /old_locus_tag="H4W23_34170"
                     /pseudo=""
     CDS             3908..4539
                     /codon_start=1
                     /db_xref="GeneID:95693681"
                     /inference="COORDINATES: protein motif:HMM:NF012464.5"
                     /locus_tag="H4W23_RS34185"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34170"
                     /product="recombinase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNGPADGFRHLLIDCARVSTADQNPHHQLDALLRAGVDRDNVHVD
                     TASGAKASRPKVDLVMQLLREATR"
     cand_cluster    3924..26455
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3924..26455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[13923:16455](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      13924..16455
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     misc_feature    4526..4528
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4737..4979
                     /db_xref="GeneID:95693682"
                     /locus_tag="H4W23_RS34190"
                     /old_locus_tag="H4W23_34175"
     CDS             4737..4979
                     /codon_start=1
                     /db_xref="GeneID:95693682"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34175"
                     /product="hypothetical protein"
                     /protein_id="WP_055640219.1"
                     /transl_table=11
                     /translation="MSNESVGGPLPDPWRPVNITVPLSVANNLDQMQGVIRDVMTQLGC
                     PTCHSGRDLRIKIATDFVVNPAGQVRQGLDVSFGG"
     gene            5001..6431
                     /db_xref="GeneID:95693683"
                     /locus_tag="H4W23_RS34195"
                     /old_locus_tag="H4W23_34180"
     CDS             5001..6431
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693683"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016970.5"
                     /locus_tag="H4W23_RS34195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34180"
                     /product="DUF692 family multinuclear iron-containing
                     protein"
                     /protein_id="WP_055640218.1"
                     /sec_met_domain="DUF692 (E-value: 6.9e-32, bitscore: 109.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLTYVPGLDRILDVCADLVDVVEIEPQTFWRSRTDGVISTDEEA
                     LRRLADLPGARLLHGVGNPVGGCQLPDRRHIALFGELAERLATPWVSEHLAFNQVGGKE
                     KGFHTGFMLPPCQTPSGVQYGIRSIRAMADALPMPLAVEIGANYLQPRPNELPDGEFIC
                     RVVEGSGCGLLLDLHNVLANERNGRCSVDELLDALPLERVWEVHLAGGLAHRGYWLDAH
                     SGLPDDDLLSLAERVLPRLPSLRAVLYEVTPSAVPQLDAQAVRELLNRVRSMWPDTSRA
                     LLPALPTPRLADDSGGCGEDTPTPQEWEHALGSLAIGRDTSTPLARQLSTDPAIGLLRE
                     LITEFRGSALTGTLRYTLRLLLLTLGDAEVRELLEAYTRAHPPHLFASQEAFAFADYLR
                     RTRPAVPWLSDVLELDCGLTRAQLDGKPCTVSLDSDPTALLTDLGAGRLPVAPRHGPFR
                     VQLVDDGRTAVGAPTGHF"
     gene            6818..8002
                     /db_xref="GeneID:95693684"
                     /locus_tag="H4W23_RS34200"
                     /old_locus_tag="H4W23_34185"
     CDS             6818..8002
                     /codon_start=1
                     /db_xref="GeneID:95693684"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34185"
                     /product="hypothetical protein"
                     /protein_id="WP_055640216.1"
                     /transl_table=11
                     /translation="MSEILINTSTPGNQERPTVADLFGTHYLVCWNDQNDGTIRAQAYK
                     ANGTPTGSEFVVNGTAPNPVRRTRPTATNTPSGPVVAWIEEPTTPGQRYVKVQRFDQTR
                     NRVGDEIKVSSHEIDPMYHPALTNVSDGFVVAWIDSRFDHRIRARRFGPDGAPVGAEFP
                     INTGDGFHESPIATTLGGGNYVIAWRTGPEGVGGGRLAFRIFEPDGTAVTGEVKPNLSG
                     FTRPKAIAALHQPSVEDGRLVLGSNFALAYVRALPNDQSRVYAGVYGADGTEQVIAVPA
                     TDAPGITSSSPALATLSNGKYLVSWVQSDGAGVAPSVRARVYDVANGPIGTEVKADTGT
                     ATERRNLSAGAVFEGGEGDTAFLAWADEGGAAGDTSGLAVRGRTFTVTSQGQLM"
     gene            8063..8287
                     /db_xref="GeneID:95693685"
                     /locus_tag="H4W23_RS34205"
                     /old_locus_tag="H4W23_34190"
     CDS             8063..8287
                     /codon_start=1
                     /db_xref="GeneID:95693685"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34190"
                     /product="hypothetical protein"
                     /protein_id="WP_055640215.1"
                     /transl_table=11
                     /translation="MKTYETSEEARAAPALLHDYTEVDALLSEVVPLVLELAYLTASAR
                     VTDNRYDGDRVDVWIAARTHTAQTAAPAP"
     gene            complement(8584..9612)
                     /db_xref="GeneID:95695069"
                     /locus_tag="H4W23_RS41705"
                     /old_locus_tag="H4W23_34195"
     CDS             complement(8584..9612)
                     /codon_start=1
                     /db_xref="GeneID:95695069"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS41705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34195"
                     /product="hypothetical protein"
                     /protein_id="WP_055640214.1"
                     /transl_table=11
                     /translation="MVRHLLLDQAETQALEDARHHAASADPDSEEVPADPAPALSEELL
                     LACLPALCLPELAELPNPQVTARRTLHHIANRVHKNPRLATLAADQLHAAADALTTHGR
                     LLSPPAKQDGDCDFDNRLLNLADDLALLSAHPDHLARACTQLAGLEQPAVVSPAPSRTL
                     IRVIGNLDPDHDRPARLLERHNWHRRVQALAALAANPHTPRTAVTDALDGLHPAEPAWI
                     SEKADGPDWFLDATAAVPADEGEDDGVLRLISDDELDKYPDPAAVLQSCSPGSTPPPPA
                     RSSPEAKPEIALKILLDRCGRNTDRWAALAAAMTFRYDEEKITFGYLLDSLDSTPAGTQ
                     KS"
     misc_feature    complement(9764..9777)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.01"
                     /tool="antismash"
     gene            10032..11012
                     /db_xref="GeneID:95693686"
                     /locus_tag="H4W23_RS34215"
                     /old_locus_tag="H4W23_34200"
     CDS             10032..11012
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693686"
                     /gene_functions="other (smcogs) SMCOG1206: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033550.5"
                     /locus_tag="H4W23_RS34215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34200"
                     /product="ISL3 family transposase"
                     /protein_id="WP_230883340.1"
                     /transl_table=11
                     /translation="MRSTAAGVSCPDCGAWSAQVHGSYLRFPADAPSAGRSVVLQLLVR
                     RFTCRNAECGRRTFVEQIPGLTRRHGQRTERLRETLAAIGLALAGRVGARAHIVGVPVS
                     RSTVQRLVDALPEPEVPAPRVVGVDEYATRKGRHYGTVLVDVETRRPVALLPDRESSSL
                     ASWSTQRPGIEVVCRDRAPFFDEGATAGAPQAVQVADRWHLWHNLSEAAERSVTQHRQC
                     LRALLPEKPEPTETEPDPTQESSGSPWPTGHRFADRTRTMHARIHALVEAGHGRRAIQR
                     QLGMTSRTVKRYAGAARPEDLFTGQWQARTSVLDEYKTYLDERWN"
     gene            11049..11378
                     /db_xref="GeneID:95693687"
                     /locus_tag="H4W23_RS34220"
                     /old_locus_tag="H4W23_34205"
     CDS             11049..11378
                     /codon_start=1
                     /db_xref="GeneID:95693687"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34205"
                     /product="hypothetical protein"
                     /protein_id="WP_107105442.1"
                     /transl_table=11
                     /translation="MPLGYQGSYQRVRAYLRLKRKSPRPVMERPPSSRAVAGWILSRPE
                     TLSETEHLQLKNVRANCPEIGALTMHVRSFATMLAERQGERLADCLSTPAVDLDLHGRE
                     AACLR"
     gene            complement(11348..12321)
                     /db_xref="GeneID:95693688"
                     /locus_tag="H4W23_RS34225"
                     /old_locus_tag="H4W23_34210"
                     /pseudo=""
     CDS             complement(11348..12321)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611994.1"
                     /locus_tag="H4W23_RS34225"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="H4W23_34210"
                     /product="IS701 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSRIAGRFARVEPRRRVRRLASGLLSDLPRKNC"
     gene            complement(12428..12880)
                     /db_xref="GeneID:95693689"
                     /locus_tag="H4W23_RS34230"
                     /old_locus_tag="H4W23_34215"
     CDS             complement(12428..12880)
                     /codon_start=1
                     /db_xref="GeneID:95693689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115045.1"
                     /locus_tag="H4W23_RS34230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34215"
                     /product="hypothetical protein"
                     /protein_id="WP_055640213.1"
                     /transl_table=11
                     /translation="MAETWDEVQLIADGFERVYAELEWYDGPRVGLADVNGKPHYFQNH
                     DYDHADEADEYQVWPASEAAVELEREQWAIFARWNECHEAGAVDLETHPGQGGIDARYD
                     ELALLLVPCRQAPDDARRLVGEIRFDAGARYRVEGLDYWFRWRPTR"
     gene            12915..13148
                     /db_xref="GeneID:95693690"
                     /locus_tag="H4W23_RS34235"
                     /old_locus_tag="H4W23_34220"
     CDS             12915..13148
                     /codon_start=1
                     /db_xref="GeneID:95693690"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34220"
                     /product="ISL3 family transposase"
                     /protein_id="WP_055640212.1"
                     /transl_table=11
                     /translation="MITIYGWSINAVRQDDLPSLHTLASGLERDRDAVITGLTLPWNSA
                     VVEGHVNRIKMFKRQMFGRAGFQLLRKRVLLA"
     tRNA            complement(13161..13234)
                     /anticodon=(pos:complement(7582027..7582029),aa:Ala,
                     seq:cgc)
                     /db_xref="GeneID:95693691"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="H4W23_RS34240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="H4W23_34225"
                     /product="tRNA-Ala"
     gene            complement(13161..13234)
                     /db_xref="GeneID:95693691"
                     /locus_tag="H4W23_RS34240"
                     /old_locus_tag="H4W23_34225"
     misc_feature    13298..13311
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    complement(13299..13312)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            <13359..>13670
                     /db_xref="GeneID:95693692"
                     /locus_tag="H4W23_RS34245"
                     /old_locus_tag="H4W23_34230"
                     /pseudo=""
     CDS             13359..>13670
                     /codon_start=1
                     /db_xref="GeneID:95693692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735775.1"
                     /locus_tag="H4W23_RS34245"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="H4W23_34230"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGDDQMWGINRRRKGIEHTWAALRTIRAARPDGAPVYVILDNLSA
                     HTKWRMKRWAARNKVELCFTPTYASWANPIEAHFGPLRQFTLANSHHPNHTIQTRALHA
                     "
     misc_feature    13367..13381
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.26"
                     /tool="antismash"
     misc_feature    13602..13604
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13924..16455
                     /db_xref="GeneID:95693693"
                     /gene="lanKC"
                     /locus_tag="H4W23_RS34250"
                     /old_locus_tag="H4W23_34235"
     CDS             13924..16455
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693693"
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="H4W23_RS34250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34235"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_107105443.1"
                     /sec_met_domain="micKC (E-value: 4e-192, bitscore: 639.3,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-07, bitscore:
                     29.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKPLPTRAAALVGFPSRCRKCRYGHYTERLRSTLEWRPISGRVG
                     GSGRSVPFGPERWQAEGTRPEQQGWKIHLAALPEEAPSTLAAASSICFAAGVPFKFLRS
                     PDMLRIMSATHTPRSSSGKFLTIYPADDAQFSKLVEELSTALTGRRGPYILSDLRIGNS
                     PVHVRYGAFRPRYRPGPDGVPTPVLRGPAGAFEPDERRPVFRVPTWVTIPDVLVPHMAA
                     RENDTESGPPYVVRDALHFTNAGGVYLADDPRTGDRLVLREARPHSGLDPFGADAQERL
                     RREYATLRRLAGLPCVPQVFGLHEIWGHLYLAEEYVEGETLLHAVIARSPLVHVGHTRQ
                     DLADYIAWVDGVVGSIRKALAAVHTNGMAFGDLHPGNVIIRLDGSAALIDFEYAAALDE
                     PAAPRPGAAGLTPPAHLTGAEADLHALDMLRLWMLMPMTELRDRHPGKATTMVRLAINR
                     YPFPAGESVPEPDDDENAVRALFGIPDHDAGWLDGRAARPDWSALRRALTAGVHSAATP
                     ERTDRLFPGAPEVFTYGGHTLAHGAAGVLGALHRIGEPVPETYTEWLLAAARRADANAG
                     GGLFHGLHGTASVLADLGRREEALELADRAVEPPPSARGLATGAAGVGVVQLKLGNLTA
                     ALRIGERLADEPADPPDEAGLLLGMSGPALLHLALYQATGDTQWIRASRAALAQDISRC
                     VTRPDGTVQVQRSGDRYLVYLGMGSAGIAMVAHAYLAAAGEDDPEIAAFVAGTRLACTN
                     LFVREPGLLQGRAGLVAGLAALDAPRAAVTAQAARLAWHGVHDSGRLLIPGAQMLRFSA
                     DLATGAAGVLLALHAALTDTPVSPLSLLALD"
     misc_feature    complement(16630..16645)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.14"
                     /tool="antismash"
     misc_feature    complement(17005..17017)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     gene            17458..17955
                     /db_xref="GeneID:95693694"
                     /locus_tag="H4W23_RS34255"
                     /old_locus_tag="H4W23_34240"
     CDS             17458..17955
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693694"
                     /inference="COORDINATES: protein motif:HMM:NF013698.5"
                     /locus_tag="H4W23_RS34255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34240"
                     /product="transposase"
                     /protein_id="WP_230883167.1"
                     /transl_table=11
                     /translation="MLAGVRDLIGAWPPASSPSCPSAWAAHADPVPIRKDGRNELGRLR
                     TAAGLATYPGRGHRGRGTGAYGAELARFLTASGITVVEVDRPARKARRAHGNSDPINAY
                     AAATAVLSGRASGTPKSRDGIVEAIRALRVVRKSAVKARTQTINQIRAPMVTAPCALRD
                     KL"
     gene            complement(18150..18680)
                     /db_xref="GeneID:95693695"
                     /locus_tag="H4W23_RS34260"
                     /old_locus_tag="H4W23_34245"
     CDS             complement(18150..18680)
                     /GO_process="GO:0042546 - cell wall biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561915.1"
                     /locus_tag="H4W23_RS34260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34245"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_055640210.1"
                     /transl_table=11
                     /translation="MARFDVVKATFWGEGVYGVQPPLTDAVVQDAENRLGVRLPASLLE
                     ILRVQNGGLVAELSNAFPTDVPTSWSENHVPLDDMMGIGRRNDRLSLLDSPYLVEEWGL
                     PSPVVLLSGDGHCWIALDYRACGESGEPSVTWFDLDTDTELPLATDFQTFVERLTAAAS
                     FDLDDADGSRSAS"
     misc_feature    19373..19387
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            20150..20368
                     /db_xref="GeneID:95693696"
                     /locus_tag="H4W23_RS34265"
                     /old_locus_tag="H4W23_34250"
     CDS             20150..20368
                     /codon_start=1
                     /db_xref="GeneID:95693696"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34250"
                     /product="hypothetical protein"
                     /protein_id="WP_055640208.1"
                     /transl_table=11
                     /translation="MPSYSPELNPDELVNADLKRSLPHTHRARNQAELAAGTRRFFRRR
                     RRQPHIVRGYFGGSRVRYVLDENPLSF"
     misc_feature    complement(20178..20193)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(20681..20695)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    20898..20916
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    21049..21063
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.5"
                     /tool="antismash"
     gene            21206..21385
                     /db_xref="GeneID:95693697"
                     /locus_tag="H4W23_RS34270"
                     /old_locus_tag="H4W23_34255"
     CDS             21206..21385
                     /codon_start=1
                     /db_xref="GeneID:95693697"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34255"
                     /product="hypothetical protein"
                     /protein_id="WP_055640207.1"
                     /transl_table=11
                     /translation="MNRQWPGTYLDDPLLPLLTAAEARDAVGYMRLLETLDLTPRGQAA
                     GRLAADLARRLPAD"
     gene            21605..21733
                     /db_xref="GeneID:95695070"
                     /locus_tag="H4W23_RS41710"
     CDS             21605..21733
                     /codon_start=1
                     /db_xref="GeneID:95695070"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS41710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269076276.1"
                     /transl_table=11
                     /translation="MPKPEADPEERELREITEQVRALTPTKRTRLTGTIQGLLRQS"
     misc_feature    complement(21804..21819)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            21886..24090
                     /db_xref="GeneID:95693698"
                     /locus_tag="H4W23_RS34275"
                     /old_locus_tag="H4W23_34260"
     CDS             21886..24090
                     /codon_start=1
                     /db_xref="GeneID:95693698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015034604.1"
                     /locus_tag="H4W23_RS34275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_34260"
                     /product="VCBS repeat-containing protein"
                     /protein_id="WP_055640206.1"
                     /transl_table=11
                     /translation="MRFRSTRSRLAAAITAVLAATALSAGTLATAPAAFATTSASAGQA
                     DATLPVYPEDSYLAGAGTTGFFTYDYDEADSITDLVWTPYDGGASKRLRHPKGGGYALV
                     GNDVAVVGDESWSAGMRSITLWNMADPAAPGVDIDLGALGGRYVAALSPTSVLTSIRKG
                     DDTEELVVVTKKGTTTTTRKITGLPVDAIEIDGSTVLGGTVVVRYAAGPPDARTGHRAL
                     IDVAAGTVTETFSSAEAGYNSDWGHLTFSASQVAWVAETDGHQTYVTSVDRTTGKEKKT
                     VLGDSIDDWCYELVGDWLVYGAYWTPVKAVNLATGETRELEVTATESAPSADGSAALRG
                     SRDADGDGLFRVEPGADGTPTVTKVAETGTRLAIDEVHVPSAVNLDQTGGKVTLGWTLS
                     RADAYLDVTLTHTATGREFKKRLTATGTRFSFDWDGVIAGADAPNGSYAIEAEATLLDG
                     TGEPVYQGWLMNVVRTVNPHDFTNNGSTDVLARDASGALWRDDLRDRPVGGQIKTAGRT
                     KVGSGWNTYKQIEAVGNIAGSTHGDLIALDGTGVLWQHQGKGDGTFATRVKIGGGWGIY
                     NKLAGGSDLNGDGRADLLATDAAGVLWFYRGTGSATAPFGTRTKVGGGWSIYNQLTAVG
                     NIAGSAYGDIVARDAAGVLWLYQGHGTGFSTRLKVGSGWGAFSQLVGAGDVNGDGRPDL
                     IAYGSGGTYVYRSTGSATAPFTRMTTNLYAGEGTKFNSVL"
     gene            complement(24818..>25409)
                     /db_xref="GeneID:95693699"
                     /locus_tag="H4W23_RS34280"
                     /old_locus_tag="H4W23_34265"
                     /pseudo=""
     CDS             complement(24818..>25409)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95693699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="H4W23_RS34280"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="H4W23_34265"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RFSEWTKARVWAKLYRLVLDDLGSRGELDWSRCAIDSVNMRALKR
                     GT"
     gene            25515..26093
                     /db_xref="GeneID:95693700"
                     /locus_tag="H4W23_RS34285"
                     /old_locus_tag="H4W23_34270"
     CDS             25515..26093
                     /codon_start=1
                     /db_xref="GeneID:95693700"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS34285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_34270"
                     /product="hypothetical protein"
                     /protein_id="WP_152335202.1"
                     /transl_table=11
                     /translation="MGSHFSPGFHYHRKATMMSNFSDWQDRMLRAVWRHGEQLPEEVLT
                     WMAELYGERGEVPEPEFCESWTARTFSMARSAFETVTKSAEQDTGKATTGDDFTYITYV
                     RDPELGPVGVVHIKSAEVSTPDSEEVLCAVTEGVQEFVMSHHRVTWPVCGEHGRGLHVG
                     YVHETPVWTCTGGTTDGHVVRAIDPAVQL"
     misc_feature    26243..26258
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
ORIGIN
        1 gcctgtccat gcgtgtgccc gcgggcccgg atccgggccc gccagacgcc tgccatcgcc
       61 gccgtgagct caccggcgaa ggcgccgggc aactcctcgt cgagcggtac gcgcatccgg
      121 acaccgtcgg gacgcgtcac ctccgccata acctcggcgc ggccttcgac cggcaggcca
      181 tactcggtga gtacggcgtc gatgcggagg gtggcgcccg gttccatgct tgactgggtg
      241 actcgggcgt cgaaacgcag attgctccag gagctggcgg agacgctgta gcgcggaccg
      301 tgggccatca gccgttccag atcggtaccg cgtgccggat cctcctcgac cgccgccctg
      361 agcctgacga tctcctcgcg gagagcgtcc tcgtcggcgc gtagccgcac ctgccaggtc
      421 ccaccatggg caccggcccc cacgggcagg ggcagtccga agcggcagaa ggtcatgttg
      481 gtgccgcgct cgacggtcgc gccgagcgcg gcgagatcgg cttcggagat cagctcgccc
      541 gccggcgtct ccagcgcgag gtccaccgcc ggtacgtcca ccaggagggt gacggtcgcc
      601 tcgatgtccg cctcggtgag ccggaacggg acccgcacct cctccccggc ggcgatgacc
      661 cccgacgggt cggtcaccac actgtcgttg gtggccgaga ccaggatctg ctggaagtac
      721 ttggacagcc ggaagtagct gtcggtgtca gtgccgagcg cgtcggtgag cagcagatag
      781 ccgccggtcc cgttcgtcag cttggtcagc gcgggggcgc tgacctgctg cgcggagccc
      841 aggccgatgg cgaacgtccg cgcgtcgatc agcccgctga cctcgtcgag gaacttcggc
      901 tggttctcca gaccgtcagt cagcacgacg attgccgagt cggtgaagga gctgccgttc
      961 gccgccagga gctggtgggc ggcttccacc ccgtccccga tggaggtact gccgctgggt
     1021 gccaggccgt tgaccgccgc caggacgtcg gcgcgctggc tgagcagggg cccgaagggc
     1081 gcaagtttca ccccggaatg cgcgtcctgg tcgaagctca ccatccccgc cccggaggcg
     1141 tcgcggatca gctcgacgca ccgcgaggcc gcctcgtgaa gtaccttcat acgggtgggg
     1201 ccggtacccg ccggcaggct catactgccg gacttgtcca gggcgaaggc gaccccggtg
     1261 gtcggccgct ggaccgtgtt ggccgtgagg acgaagtcga agtcctcgcc ggtctccaca
     1321 cagcggatcc ttacagcgcc gttggcggcc gcccccgggg ccgccgcacc ggtgaaggcg
     1381 aaccagaccc gggccagatc gaagggcgcg ttgtccacca ctggcgtatg ggtcaccgac
     1441 ccgcccagtg aagtgagcgc gtatggcgcg gccagtccgc tgcccggcac gacctccagg
     1501 gtgaccggcg agccggccct gatccggaag acggctgcct gccaggtggt ttccagcgtc
     1561 gggacgtcgt ggaagttcac cgtgagggag accgcctcga ccagcggcgg gtccgtgtcg
     1621 tagatgaagg cgagagtgcg ccggtagtcg agcgagcggg cgggcgtcgg gtcgacggtg
     1681 gtgaggtgct gcatctggtc gccgaggttg tgcccggcgg ggccgccgct cgccgggagg
     1741 tacggggccg ccgggtgcgc gtgctgccag cgggcccaca ggcggtcgac attgcagtgg
     1801 tggaggaaga agacgggatc gttgggcgag gtgccggggc ccatgtcccc gccgacccag
     1861 atatggaccc ggttgtgcag ctgcgagccg ccctcggagg ccacggcgag ccaaccctcc
     1921 agacgattgc ggacgccgtc gtcactgccc agatgccagg gggccttgtc gtagaccgcc
     1981 cagttcagga cagcgtcctc cacctgggcc gcggtcggga acacaggcat gttccgcgcg
     2041 gggttgggcg tggtcgtgcc agggaacgtg atctggcttc ccagcttccg caggatcccg
     2101 ccaggccggg gtacgagggc gcccgccgcg ttctcgatca gtgcggtcca gcccgcgaag
     2161 ggccccgtgg tcacctcgcc gttggggccg tcgccgtcgc cgcccacgta taccgggccg
     2221 gcggccgggt tcgtgttcca cagcttcgcc gcggcggggt tggccgcgtc ggcggaccag
     2281 tcccagtacg ggagggtgac gttcggcttc ttcttctgga gcagaagttc cagttcgcgg
     2341 cagaagtacc ggtgccaggg caggaacgcc ggtccgcggt gcgcgacgtt gcgcaccatg
     2401 tcattcggag gctcccccgg catgggggtc gcggtcatca tcgcgtggtg gtggcggtgg
     2461 atgaagtcgt cgtagctgcc atcggccttg atcgcgttga gcgcggccag gaagtcggcg
     2521 agttcctgcg gggtcaggct gtagatgttc ttgcggatgt tcaccggtcg cctcccccct
     2581 catgcccgtg gtgaccaccg tgccccgtgc cgtgcccccc gtttggggcg ccatgcggat
     2641 gtgctccgcc actggtcccg ccgtgcaagg tccacgtctt cccctcggtc tccagcagcg
     2701 agtccaccag cgcgtccatc gtggggaatc cggtgaactg gttggcgagc tgactgtggt
     2761 actcgccgtc gaggtaggcg acggcgatgg gagtgtcgtc cagccggagc tcgatctcgt
     2821 cgttctccgc cgtgatccgg acgtccaccc ccctgctcac gtagtggcgg cttcctggtg
     2881 tgtcgggcac gtcagctcct tcggctgtgg acccacgggg ggtctcgctt cagtagagat
     2941 gttcgactcc cgatgcattg tgtgatcgct cagtggcctc tcgctgcgcc acgccgtcgg
     3001 ggggctgacc ttgacccgaa cggcaccgga agcaagtcct gagcgacaag gcgggctttc
     3061 gccggctcag caggacgaga tctggagacg ctggcgtgag gggcagtcgt tcagcttgat
     3121 cgggcgggcg ctcggggcac cgatgcagca tgcccgtcgc ttcctgtacc agagcggcgg
     3181 cgtccgcctc atcccgcaga tcgaccgcag cctcacccag ccactgcggt caggcaggcc
     3241 aatgcgccgg ccgaagatcg cccgtcggcc caccgggcgg gtcgtcatcc gcggcatggt
     3301 gtccatcgcg gcccgtcccg ccgaggtcga gaaccgcaag gtccccggcc atggggaggg
     3361 cgacctcgtg aggggcaccc ggccctcggc cgtcgcgacg ctcgtcgacg caccagtcgc
     3421 tacacggcca tcgttgcgct gccggacggc ctcaaggctg agcaggtcgc tccgcacctc
     3481 accaggactc tcctcggcat cccgccccag ctacgacgaa cgctcacctg gcaccgggtc
     3541 cgcgagatgg ccgagcacca tgccatcacc gccgagacgg gtatgccgat ctacctctgc
     3601 aagccgcgga gcccttggca gcgcggcacc aacgagaaca ccaaccggct gcttcggcag
     3661 tacctgccga agggcgcgga ccttcgcacg ttcagccagg ccgacctgga cgccatcgcc
     3721 cacgagctca accaccgtcc atcgcaagac ccacggctac cgcactccgg cagatgtcta
     3781 cgctgacctc ctgaacagcg gtgatgcgct gaccgcttga gctcgccacc gcctgccgac
     3841 acttcggccg gcgatcacga acccgcaggt gggcactgtc gacaactcgc gtcggaaatc
     3901 aacgtcggtg aacggtccgg ccgatggatt ccgacaccta ctcatcgact gcgcgcgggt
     3961 ctcgaccgcc gaccagaacc cgcatcatca gcttgacgcc ctgctgcggg ccggcgtcga
     4021 ccgcgacaac gtccatgtcg acaccgcgag cggcgcgaag gcgtcccgtc cgaaggtcga
     4081 cctcgtcatg cagttgctcc gcgaggcgac acgttgaagg tcactcggct cgaccggctc
     4141 tcccgctccg tgctgcatct ggtgaccctc ggctccgagc tgcgcgagag cggcgtcggt
     4201 ctgcacgtca tcgagcacgg catcgacacg tccacgatgg agggccaggc gatgttcggg
     4261 atgctgtccg tgccggccga gctccagcgc gagctgatcg tggcgaacac gaacgacggg
     4321 ctcgcctccg cgcgggcccg cggccggatc ggcggacgcc gccccgagct caccctggac
     4381 caggccgaac gtgcccagca gctctacgac gcccgcgaga agaacgtcct gcagatcgtc
     4441 gacatgttca acgtgccccg ctctacggtg tacgggcacc tcgacaagac caagaccttg
     4501 acccgtcagc cgaagaagac cgcggttacg aagtcctgac cgctactttg cggctggtgt
     4561 ccgagccagg agtccggggg cacacactgt gaggcggccg ggtgattggt cactctccga
     4621 cggcactcag gcgcgtctca tcgctgagtg tgacgacgtg ttgcatgatg accactgagg
     4681 gcacattcgc atgagctcca tgggagccgc ctgcggccag agtggaagga ttggacatgt
     4741 cgaacgagtc agtcggagga ccgctacccg atccgtggcg gcccgtcaac atcacggtcc
     4801 cgctgtcggt ggcgaacaat ctcgatcaga tgcagggcgt gatcagggat gtgatgacgc
     4861 agctggggtg tcccacctgc cattcggggc gtgatctgcg catcaagatc gccacggact
     4921 tcgtggtcaa cccggccggc caagtgcggc aggggctcga tgtgtccttc ggtggttagt
     4981 gggccatgag gcggctcggt gtggggctca cctacgtacc cggcctcgac aggatcctcg
     5041 acgtatgcgc cgacctggtg gatgtcgtcg agatcgaacc gcagaccttc tggcgttcgc
     5101 ggacagacgg cgtgatttcg accgatgaag aggcgctgcg ccggctggcg gatctgccgg
     5161 gcgcccggct gctgcacgga gttggcaacc ccgtcggagg ttgccaactg cccgaccgcc
     5221 gccacatcgc actcttcggg gagctcgccg agcggcttgc cacgccgtgg gtgagtgagc
     5281 acctggcgtt caaccaagtc ggcggcaagg aaaagggctt ccacaccggc ttcatgcttc
     5341 cgccgtgcca gacgcccagc ggtgtccagt acggcatccg gtcgatccga gcaatggcag
     5401 acgcgctccc catgccgctc gcggtggaga tcggcgccaa ctacctccaa ccgcgcccga
     5461 acgagctccc ggacggcgag ttcatctgcc gggtggtcga aggaagcggc tgtggcctgc
     5521 tgctcgatct gcacaacgtc ctcgccaacg aacgaaacgg ccgttgcagc gtggacgagc
     5581 tgctggacgc tctgccgctg gagcgagtgt gggaggtcca tctcgccggc ggcctcgcgc
     5641 atcgcggcta ctggctggac gcccacagcg gcctccccga cgacgacttg ctgtccctcg
     5701 ccgaacgagt tctgccccgc ctgccgtcgc tccgagcggt cctgtacgag gtgactccat
     5761 cggccgtacc gcaactcgac gcgcaggccg tccgtgagct gctgaaccga gtacgctcga
     5821 tgtggccgga cacttccaga gcgctgctgc ctgctttgcc cactccgcgt ctggcagacg
     5881 actcaggcgg ctgtggcgag gacacaccga caccacagga gtgggagcac gccctcggca
     5941 gcttggcgat cgggcgcgac acaagcaccc cactggcgcg gcaactgtcg accgaccccg
     6001 ctatcggact gcttcgtgag ctcatcaccg agttccgggg cagcgccttg accggcaccc
     6061 tccgctacac gttgcgactg ctgcttctca ctcttggtga tgccgaggtg cgtgaactcc
     6121 tcgaggccta cacgcgcgcc caccccccgc acctcttcgc ctcgcaagag gcattcgcgt
     6181 tcgccgacta cctgcgccgc acccgcccgg cggtcccgtg gctgagcgac gtactcgagc
     6241 tcgactgcgg cctcaccagg gcgcaactcg acggcaagcc ctgcacagtg agcctcgaca
     6301 gtgacccgac cgccctgctg acagacctgg gggcgggacg cctgcctgta gccccccgcc
     6361 atgggccatt ccgagtgcag ctcgtcgatg acggccggac cgctgtaggc gcaccgacgg
     6421 gccacttttg atgtggctga gcacggaggt tgtcacctcg aggacatccg tgacggcgcc
     6481 cagcgtggtg atctgcttca gcaccgcgcc ggccccgggg acaggagcct gtgcgacgac
     6541 gggtctctcg ggcccgacgg cggccgaggc cagacccggg gacgcggccg gcagcgtgaa
     6601 ggtgagggcg gcgggaacgg tttaaggagt gaagcgaaac cccttccgta acttcagcac
     6661 cacttcagtc atccacgaca cgccgcgcac ctggccacgt atcgccctga cctgtgcgga
     6721 catcatcgcc cttcgctgct cacccgacgg actgtcagat ttgggccacc accctccgta
     6781 gcgtggacag gggcaaatcc caaggaggca ggtactcatg tccgagatcc tgatcaacac
     6841 cagcaccccg ggtaaccagg agcggcccac ggtcgccgac ctgttcggca cgcactatct
     6901 ggtctgctgg aacgaccaga acgatggcac catcagggcc caggcctaca aggcgaacgg
     6961 aacacctacg ggctctgaat tcgtcgtcaa cgggaccgcc ccgaacccgg tgcgacgcac
     7021 gcgcccgacg gcgacgaaca ccccctccgg tccggtggtc gcctggatcg aagagccgac
     7081 gacacccggt cagcgctacg tgaaggtcca gcggttcgac cagaccagaa acagagtcgg
     7141 cgacgagatc aaggtcagca gccacgagat cgaccccatg taccaccccg ccctgaccaa
     7201 cgtgagcgac ggcttcgtcg tggcctggat cgactcgcgc ttcgaccacc gcatccgggc
     7261 gcggcggttc ggccccgacg gagcgccggt cggagcggaa ttcccgatca acaccggcga
     7321 tggcttccac gagagcccca tcgcgaccac gctgggcggc ggcaattacg tgatcgcctg
     7381 gcgcaccggc cccgaaggag tgggcggcgg acggctcgca ttccgtatct tcgagcccga
     7441 cggcacggcg gtgacaggcg aggtcaagcc gaacctctcc ggattcaccc gcccgaaggc
     7501 catcgccgcc ctgcaccagc cctccgtcga ggacggccgg ctggtgctcg gcagcaactt
     7561 cgccctcgcc tacgtccgag ctctcccgaa cgaccagagc agggtgtacg ccggcgtgta
     7621 cggggctgac ggaacagagc aggtgatcgc ggtgcccgcg accgacgcgc ccggcatcac
     7681 ctcctcgtcc ccggccctgg ccaccctgtc gaacgggaag tacctcgtgt cctgggtcca
     7741 gagcgacggc gcgggcgtcg ccccgagcgt ccgggcccgg gtctacgacg tcgccaacgg
     7801 cccgatcggc acggaggtca aggcggacac cggtacggcg accgagcgcc gcaacctgtc
     7861 cgccggcgcg gtcttcgaag gcggcgaggg cgacacggct ttcctggcct gggccgacga
     7921 gggcggggcg gccggcgaca cctcgggcct cgccgtgcgc ggccgcacgt tcaccgtcac
     7981 ctcgcagggc cagctgatgt agccgtcagc gcctcggcga agcccactgg ctcagcacca
     8041 gaatgtcctc gccggtggct tcgtgaaaac ctacgagaca tcggaggaag cccgcgcggc
     8101 cccggcgctg ctgcacgact acaccgaggt cgacgctctc ctctcggagg tcgtccctct
     8161 cgtcctggag ctggcctacc tcaccgcctc cgcgcgcgtc acggacaacc ggtacgacgg
     8221 cgaccgggtc gacgtctgga tcgccgcccg gacccacacc gcccagaccg ctgccccggc
     8281 accgtgatcg atgtcggggc gtaggcggac ctcgacactg tgaatcccgc cgaggtctcg
     8341 tgggcgcccg accgcgacgc tccggacgag cagcatgcag cccgcaccgc aggccgcctc
     8401 tggggcgaga cctgcgccaa ggacgaggat gcgggccgtg tccgctacga actgtcgtcc
     8461 ctacggcacg tttccgacgt attccggttg cccaccccgt agcgcaccaa ccggaggtca
     8521 cgctgcgagc cgcttcatcc ggtcgccgtg gcagccgatc gaccgccact caccagcagc
     8581 ccgtcaggac ttctgcgtgc cggcaggcgt ggagtccagg gagtcgagga ggtatccgaa
     8641 ggtgatcttc tcttcgtcgt accggaaggt catcgcggcg gcgagcgcag cccaccggtc
     8701 ggtgtttcgg ccgcagcggt ccagcaggat cttcagcgcg atctcgggtt tcgcttcggg
     8761 agaggatctc gccggtggcg ggggagtcga tccaggactg caggactgca ggacggccgc
     8821 ggggtcgggg tacttgtcga gttcgtcgtc gcttatcagg cgcagtacgc cgtcgtcttc
     8881 gccctcgtcg gccgggacgg ccgctgtcgc gtccaggaac cagtcggggc cgtcggcctt
     8941 ctcggagatc caggccggct ccgcggggtg cagtccgtcc agggcgtcgg tgacggcggt
     9001 gcgcggggtg tgggggttgg cggcgagggc ggccagggcc tggacgcggc ggtgccagtt
     9061 gtggcgttcc aggagccggg ccgggcggtc gtggtcgggg tcgaggttgc cgatgacgcg
     9121 gatcagggtc cggctcggcg cgggggagac gacggcgggc tgctccaggc cggcgagctg
     9181 ggtgcaggcc cgggcgaggt ggtcggggtg ggcgctgagg agggccaggt catcggcgag
     9241 gttcaggagg cggttgtcga agtcgcagtc gccgtcctgt ttcgcgggcg ggctgagcag
     9301 ccggccgtgg gtcgtgagcg cgtcggcggc cgcgtgcagc tggtcggcgg ccagggtggc
     9361 caggcggggg ttcttgtgaa cccggttggc gatgtggtgc agggtcctgc gggccgtgac
     9421 ctgggggttg ggcagttcgg cgagctcggg caggcacagt gctgggaggc aggcgagcag
     9481 cagctcttcg ctcagggcgg gagccgggtc ggcggggact tcctcgctgt ctgggtcggc
     9541 ggaggcggcg tggtgccggg cgtcctcgag ggcctgggtc tcggcttggt ccagcagcag
     9601 gtgccggacc aagccctcgc ccgcatcgcc agcgacgagg acgggccagc ctcaaactgg
     9661 gtcgacccgg aggactggaa gcagtggcga gccatgctca cgcaccttcg cgccgtgctt
     9721 gccccgccac cccccttcca tcgctctctt cgatgtccag ccataacgga gcgtcactcg
     9781 gcacgaaagc tgagccagaa cccgttctgg ttctggctca ggttgtgtga tccgtgcact
     9841 gtcagtaaca actgaactcc ctccgctgcc tcgggaagtt gcctcaaaac gagcagtggc
     9901 aagtgtgact gggccgacag ttaggggctg tgagtgagat cttgctccgg ctggtggagt
     9961 tgttgctccc atcgatagcg gacgtcgcgg tgttgtccgt ggacgtgaac atcgcgatag
    10021 tgcgtggtga cgtgcggtcc accgccgcgg gcgtctcgtg cccggattgc ggagcgtggt
    10081 cagcccaggt tcacggctcc tacctgcggt ttcccgctga tgctccgagt gcgggacgaa
    10141 gcgtcgtact ccagctgctg gtccgccggt tcacctgccg gaacgccgag tgcggacgcc
    10201 gcacgttcgt cgagcagata cccggcttga ctcgaaggca cggccagcgg accgagcgcc
    10261 tgcgcgagac cctggccgcg atcggtctcg ctctcgcggg ccgggtcggc gcccgcgccc
    10321 atatcgtcgg ggtgccggtc agccgcagca ccgtccagcg gctggtcgac gcactgcctg
    10381 agccggaagt gcccgctccg cgagtggtcg gcgtcgacga gtacgccacc cgaaagggcc
    10441 gccactacgg gaccgtcctc gtggacgtcg aaacacggcg ccccgtcgcc ctgttgcccg
    10501 accgcgagtc atcgagcctg gcctcgtggt cgacccaacg gcccgggatc gaggtcgtct
    10561 gccgagaccg cgcgccgttc ttcgatgagg gcgccacggc cggcgctccg caggccgtgc
    10621 aagtcgcgga ccgatggcac ctctggcaca acctcagcga ggccgccgag cggagcgtca
    10681 cccagcaccg ccagtgtctg cgagccctgc tcccagagaa acccgaaccg accgagacag
    10741 agcccgaccc cacgcaggag tcttccggct cgccatggcc gaccggccac cggttcgccg
    10801 accgaacccg gaccatgcac gccaggatcc acgccctggt cgaggcagga cacggccgcc
    10861 gcgcgatcca gcggcagctc ggcatgacga gccgaaccgt caaacgctac gcgggcgccg
    10921 cccggccgga agatctcttc accggtcagt ggcaggcccg gacctcggtc ctcgacgagt
    10981 acaagaccta cctcgacgag cggtggaact agggcggcac caacgcctgg aaactgtggg
    11041 aagagatcgt gccgctcggc taccagggca gctaccagcg cgttcgcgcc tacctccgtc
    11101 tgaaacgcaa atcgccacgg cccgtgatgg agcgtccgcc ttcgtcccgg gccgtcgccg
    11161 gatggattct cagccgcccg gaaaccctct ccgagactga acacctccag ctgaagaacg
    11221 tccgggccaa ctgccccgag atcggcgcac tcaccatgca cgttcggtcc ttcgcgacca
    11281 tgctggccga gcgccagggc gaacgcttgg cggactgcct cagtactcca gccgtagatc
    11341 ttgatcttca cggccgggag gccgcctgcc tgcggtaatg acgccggcgt gcacgggctt
    11401 gatgccggcg tcgccagtgg gaccagtgca gaaggtgggc gaggccgtgg attgggcgga
    11461 tcagtgctgc gaacaggcgc tggatctcgt tgccagtcag ggggaccagg tcgtcaggga
    11521 tgggtcggtc gcggcgttcg gctgcggcgg tgaacctcga tctgtgccca gtcgtagtac
    11581 cgctcgcctt tcgcgcctgc tccggccgac agccgctgcc aggcacgctt cgggattcgc
    11641 gcggccaggg tcggcctgga acttcccagc gtgcgtgatg acggggtggg tgctggagac
    11701 ggccaggacg tagccggtcc ggcggtgttc cagggcggtc cgcaggtgcg gggtgtcgcc
    11761 gtagacctcg tctcccgcga cccatcgggc cggtgttccc gcgtccaggg cccgctcgac
    11821 catgcgggcc gcgagctcgg gtttggcggc gaatgccagg ccgtcgggaa tacccgcact
    11881 ccgacagcgg tccgggtcct cggtccatga gcgcggcacg tacagggccc ggtcgatggc
    11941 tgcgtgtcca ccgctggcgg agtacacgag atagacggcg acctgggcgt tctcgatgcg
    12001 gccagccgtg ccggtgtact ggcgctggac gccgacggtc cccgtgccct tctttagatc
    12061 acccgtctcg tcgatcacga gcacggcctt cgtgtcttgc aggtgctcga ccacgtaggc
    12121 gcgtatgtcg tctcggattg cggcggcgtc ccatttcgca cggtggagca ggtgctgcat
    12181 gccgtccgga gtggcgtcgc cgacgtgctc ggccagggtt cagcagttct tgcgcggcag
    12241 gtccgacagc agcccggagg ccaaccgccg cacgcggcgg cggggttcaa ctcgggcgaa
    12301 ccggcccgcg atccgactca tcaggccctc gaatgcctcc tgccagtgag caggcactac
    12361 gccggtgtcc gaggtcgccg cgtgatcatt ggttgtccac acaacaccta atgatcgacg
    12421 gtggccctca cctggttgga cgccaccgga accagtagtc cagaccctcg acccggtagc
    12481 gggcccctgc atcgaaccgg atttcgccca ccagccgcct cgcatcgtcc ggcgcctgcc
    12541 ggcacggcac caacagcaag gccaactcgt cgtatcgggc gtcgatcccg ccctggcccg
    12601 ggtgggtctc caggtccacc gcccctgcct catggcattc gttccacctg gcgaagatcg
    12661 cccactgctc acgctccagc tccaccgcgg cctcgctcgc gggccagacc tggtactcat
    12721 cggcttcgtc ggcgtggtcg tagtcgtggt tctggaagta gtgaggcttc ccgttgacgt
    12781 cagcaaggcc gacgcgcggt ccgtcgtacc actccaactc ggcgtacacg cgctcgaagc
    12841 cgtccgcgat cagctgcact tcgtcccagg tctcagccac aggcgcaggc taccgacgag
    12901 cggctttggt atccatgatc acgatctacg gctggagtat taacgccgtc cgacaggacg
    12961 accttcccag cctccacacc ctcgcctcag ggctggaacg cgaccgtgat gccgtcatca
    13021 ccggcctgac cctgccctgg aattcggccg tcgtcgaagg acacgtcaac aggatcaaga
    13081 tgttcaagcg tcagatgttc gggcgcgcgg gcttccaact cctacggaaa cgcgtcctgc
    13141 tggcatgagc cagagcggga tggggctggc cggattcgaa ccggcgtcct cccacatgcg
    13201 gtgaaggcgc gacaaccgct gcgctacgag ccccatcccg cccgcgatca tacgagcacc
    13261 ctgaccccag tgctctgaaa ttatccaaga ggaactgatc actcagcgcg acgacatcac
    13321 caatcctgag ccagaacccg ttctcgtgaa caaagccagt cggcgacgac cagatgtggg
    13381 ggatcaaccg gcgccgcaaa ggcattgagc acacctgggc ggccttgaga acgatccggg
    13441 ccgcccgccc ggacggcgcc ccggtctacg tgatcctcga caacctctcc gcccacacga
    13501 aatggcggat gaagcggtgg gcggcgcgga acaaggtcga gctgtgcttc accccgacct
    13561 acgcctcctg ggccaatccc atcgaagccc acttcggacc cttacggcag ttcaccctcg
    13621 ccaactccca ccaccccaac cacaccatcc agacccgggc cctgcacgcg agaaaggcat
    13681 ccgctgggcg gcagaccacg acaaacggca gcctgaccac ccaacccggc aaaggttcat
    13741 ggtcacagcc tggtgagccc acaggtgagc gcacccggtc cgacacgcct cgtcgtgcca
    13801 ttgccgctgg tgcgtcacgt gtcgtcgtgg gccggacggc cacccgtgcc gcggacccgg
    13861 tggccgcatt ccggctcgtc cgcgccgacc tggagctgtg agcggaaatg atcaccgggc
    13921 tggatggtca agccgctccc gacgagagcg gccgctctcg tcggattccc ttctcgatgc
    13981 agaaaatgcc gctacggcca ttacaccgaa cgactacggt ccaccctcga atggcggcct
    14041 atctcaggcc gcgtcggtgg ttcagggcgt agcgtcccat ttggacctga aagatggcag
    14101 gcggaaggaa cgcggccaga acagcaaggg tggaaaattc acctcgctgc cctcccggaa
    14161 gaggctccca gcacgttggc cgccgcctcc agcatctgct tcgccgccgg tgtgccgttc
    14221 aaattcctgc ggagcccgga catgctgcgg atcatgtccg cgacacatac tccgcggtcc
    14281 agcagtggta aattcctcac catctaccca gcggacgacg cccagttcag caaactggtc
    14341 gaggagctgt ccaccgcgct gacgggcagg cgcggtccct acatcctcag cgatctgcgt
    14401 atcggcaaca gcccggtgca cgtacgctac ggcgccttcc gtcctcggta ccgtcccggg
    14461 ccggacggcg tgccgactcc ggtgctgcgg gggccggccg gagcattcga acccgacgag
    14521 cgacggccgg tgtttcgcgt tccgacctgg gtgaccattc ctgacgtgct cgtgcctcac
    14581 atggccgctc gtgagaatga cacagagtcc ggcccgccct acgtggtacg cgatgccctg
    14641 cacttcacca atgccggcgg tgtctacctg gccgacgacc ctcgcaccgg cgaccgcctt
    14701 gtcctgcgcg aggcccggcc gcatagcggg ctggacccgt tcggtgcaga cgcacaggag
    14761 cggctgcgcc gggagtacgc cacgctacgc cgccttgctg gactgccgtg cgtccctcag
    14821 gtattcggac tgcacgaaat ctggggacat ctctatctgg cggaagagta cgtcgagggc
    14881 gaaacgctgc tgcacgcggt catcgcccga agccctctgg tccatgtcgg gcacacccga
    14941 caggatctgg ccgactacat tgcatgggtg gacggtgtgg tgggcagcat ccggaaggcc
    15001 ctcgctgctg tacacaccaa cggcatggcg ttcggggacc tgcacccggg caacgtcatc
    15061 atccgtctcg acggctcggc cgccctgatc gacttcgagt atgccgcagc cctcgacgaa
    15121 ccggccgccc cacgccccgg cgcagccggc ctcaccccgc ctgcccacct caccggcgcc
    15181 gaggccgacc tgcacgcgct ggacatgctg aggctctgga tgctgatgcc gatgactgag
    15241 ctgcgggacc ggcatccggg caaagccacc accatggtgc gactggcgat caaccggtac
    15301 ccgttccccg ccggggagtc agtgcccgaa ccggacgatg acgagaacgc cgtacgagcc
    15361 ttgttcggca ttcccgacca tgacgcgggc tggttggacg gccgcgccgc ccgtccggac
    15421 tggtcggcac tgcgtcgggc cctgacggcc ggcgtgcact ccgccgcgac ccccgaacgc
    15481 acagaccggc tgttcccagg tgcccccgag gtgttcacgt acggcgggca caccctggcg
    15541 cacggcgcgg cgggtgtgct cggcgccctc caccgaatcg gcgaaccagt cccggagacg
    15601 tacaccgagt ggttgctcgc agcggcacgg cgcgccgacg cgaacgccgg cggagggctg
    15661 ttccacggac tgcatggcac cgcctccgtg ctggcggacc tcggtcgccg ggaggaagcc
    15721 ctcgaactgg ccgaccgtgc cgtcgaaccg cccccatcgg caaggggact ggccaccgga
    15781 gcggctgggg tgggggtcgt ccaactcaag ctgggcaacc tcactgcggc gcttcgcatt
    15841 ggtgagcgcc tggccgacga gccggcagac ccgccggacg aggccggtct gctcctcggc
    15901 atgagcggcc cggcactcct acacctcgcg ctttaccagg ccacaggcga cacacagtgg
    15961 atccgcgctt cccgcgccgc cctcgcacaa gacatttcac gatgcgtgac ccgaccggac
    16021 ggaaccgtcc aggtgcagcg gtcgggcgac cgctacctcg tctacctggg catgggcagc
    16081 gccggtatcg ccatggttgc ccacgcctac ctcgcggcgg ccggcgagga cgaccctgaa
    16141 atcgccgcct ttgtcgctgg aacccggctg gcctgcacga acctgttcgt ccgggaacca
    16201 ggtctgctgc agggtcgggc cggactggtc gccggacttg ccgcgctcga cgcgccacgc
    16261 gctgcggtca ccgcccaggc cgcccggctg gcctggcacg gcgtccacga ctcaggcaga
    16321 ctcctgatcc ccggcgccca gatgctgcgg ttctccgctg acctggccac cggcgccgcc
    16381 ggtgtcctgc tggccctgca cgccgcgctg accgataccc cggtctcccc gttgtccctg
    16441 ctggctttgg actgaaggat tcccgtcaga ttgctgtact ggtgagcctt cggtcttcga
    16501 gacacctgtc tcactgctcc tgctggttcc cacgatcgcc ggcgtggccg tcgcggtagg
    16561 caccgacagc accgtccgga tcctccttcc cgagcctccg cggctcatcg gtacccggct
    16621 tgcctggtgg atgacgattc tcaccgtagc tgcggccgcg gcagcgaacc tgggccagct
    16681 gatcggccct gccgtcccct ggcaggcagg gctccgcaac accctggtgc atgcctcatt
    16741 ggcggtggcg acctccgccc tggggtacat ctcccttgcc tggcttccgc ctgttggtct
    16801 cacgttggcg agcatgttgt tcggctaccc gccgtccgag ccccggtact actggtgggc
    16861 ggtcatcatg gaaagctcca ccttgggaaa cacccgctca ctaccacccc cgaacgacag
    16921 gcggccccgt tcatccgctc aaagtcgtga cctaacggat cacaaccaca acgggagacg
    16981 ccatggaact cgtcttgtgg atcgttgcaa cattcatcct ggtgagtctg gtcggcttca
    17041 tcctcagcca agggttcgta gcgttcaaaa ggaaccgagc acggcgcaac ggttgacctg
    17101 gagagcgagg aacctgaatc gtgcgcgacg tgccggtcag gcgtgccaag tgccgcacgc
    17161 cgatctgctg cgacccgtcg tcaacgagct ccaagagcag cagaagaagc acggaaatgc
    17221 ccggaccgcg taccggagga cagcctcgaa tgcgtagtcg gggcccgacg tttcagggca
    17281 tccgctgacc ggccgcgtgg tgcggacggt cagctcctcg aggacggcca ggaccgggga
    17341 cagcgggtct gacagtgagg atgtccctgg cgtcgttcag gggtctgact ccgggtctga
    17401 ctgacgtttc ggctgtccgt ctgttgaatt gtcggccgcc gggcgacgcc accgcgtgtg
    17461 ctcgcgggtg tccgtgacct cataggagct tggccaccag cctcatcgcc gtcttgtccg
    17521 tcggcctggg cagcacacgc cgatccggta cccatacgga aggacggcag aaacgaactc
    17581 ggccggctac gaacagctgc tggcctggct acgtacccag ggcgaggtca tcgcggtcgg
    17641 ggcaccggcg cctacggcgc cgaactcgcc cggttcctca ccgccagcgg catcacggtc
    17701 gtcgaggtcg accgcccggc ccgaaaggcc agacgggccc acggcaactc cgacccgatc
    17761 aacgcctacg cggcggccac cgccgtcctg tccggccgcg cgagcggaac accgaagagc
    17821 cgggacggga tcgtggaagc gatccgcgcg ctgcgtgtgg tccgcaagag cgcggtcaag
    17881 gcacggacgc agaccatcaa ccagatccgc gctccgatgg tcaccgcccc ctgcgccctg
    17941 cgggacaagc tgtgaggact gcccaccagt cggctgatcg acaccctcgc ccggacccag
    18001 cccgctggtg atctcaccga cccggcctgc gcggccaaga cggcactgcg ccgcctcgcc
    18061 cggcgctcaa gaggttcgtc gcccgcgagg tctacaggca cctcacgagc acgagcatcc
    18121 tggacacggc gggcccggcc ggagccagat catgacgccg accggctgcc gtccgcgtca
    18181 tcaaggtcga aggacgcggc cgcagtcagc cgctcgacga acgtctggaa gtccgtcgcc
    18241 agcgggagct ccgtgtcggt gtccaagtcg aaccacgtca cggacggctc cccgctctct
    18301 ccgcatgccc ggtagtcgag agcaatccag cagtgaccat caccggaaag cagaaccaca
    18361 ggagacggaa gaccccactc ctcaaccaag taaggcgagt ccagcaatga aagtcggtcg
    18421 ttgcgacggc cgatgcccat catgtcgtcg agcggcacat ggttctcgct ccacgacgtc
    18481 ggcacatcgg tcgggaacgc gttcgacagc tccgccacca ggccgccgtt ctggacccgc
    18541 aggatctcca gcaacgaggc cggcagacgg acaccgagcc ggttctcggc atcctgaacg
    18601 accgcgtcgg tcagcggtgg ctgaaccccg tacacgccct cgccccagaa cgtcgcctta
    18661 accacatcaa accgagccac gaacgcatcc tatggacctc gcagcccggc ttgacgatct
    18721 ataggagctt cacgctagtg actgcttctt gtggcccggc ggtctcgttc gcgggtcgca
    18781 cgtacggatg tgtccgtcag ctggccgccg tcccgggctc agggcgggag cggcggggcg
    18841 aggtggggcc atcgccttgc ggggcgggct gcccggtgtc cttcgtgaaa cgcagccacg
    18901 cgctcagcgc cgcctgtagc tcgaccaccg ccgcccggtc gaggacttcg cctgtcggcc
    18961 cggcgtgcag ccgcacgccc tggccggtca ccgtccaccc gacgggcagg ggtgagggcg
    19021 gagccgcccg ggccctggac cagcaggttc gtcgacccct cccacacctc gccgcccact
    19081 cccagcccct tgaccccggc gacccgacca gcgccctgat cgcgaacccc ctcgtcacct
    19141 ggcccgcgcc aagcgggcgc ctggtgaggt tgcagcgggc gctggcccgg acggagaagg
    19201 gttcgcgacg gcgggagagg gcgctctccg agcggccatt ggacacctgt gtgacatcca
    19261 tgcctgtgac aggggcaagg acgtccggtc tcgccaccgt cgcgttcgac gatggaaagc
    19321 gcgagattgc cacggaccgt tcccgtcaac gggtggtcct cgcccagcac acggacaagg
    19381 tcggccaggg cacgttggag gtggctggtc ccgcgggtga gttggccctg gtcgctgagg
    19441 aagatcccag tgccgctgag gagggtcgcg gtggtgtcgg tgtcggtttc gagagctgca
    19501 tgggccgcaa gggcgtcgat gtgggggagc agggtgcgcc aagtcggcca ggttgccggg
    19561 gtatcccagg aatcgggcag agcggtgtac agctgggtag tggcgaggtt tccggcttcg
    19621 tcgacgagtt ggggcgggcg gctccggctg ctctccggtg cggcggaagg ccacttcacg
    19681 ggttcgggct tccgggctgg tcaccggtgg agagtgggcc cttgggtcgt tccggtgggc
    19741 cggttgtcct ttcccactgg gcgcatcgtc agcagcctcg agcggcaacg ccccctggac
    19801 aaccggccgg gaccggggtc aggagaggac ccaggagcat cgtgaaccag gtggggcttc
    19861 gcagagggcg gttcacctga agagctccag agcgcgggcg ggggccgtgc gcaggctgcc
    19921 accgagcatt gtgtcgatat gaggtaggtc cgggaggact ccccgtccat ggcgtgccga
    19981 gatcgtcttc gtgaggctca gcacaagcag ccccacgctt gagcttggcg gcgctgggcc
    20041 acggcgggac cgagtccgtc cttgccgctg ggatgctggc gaccttcaat gtttcggcgt
    20101 tctccatggc gtccctgaga ggacgtttga agtaggcgta ttgccgctta tgccctcgta
    20161 ctcccccgag ctgaaccccg acgagctggt caacgccgac ctcaaacgca gcctgcccca
    20221 cacccaccgg gccaggaacc aggccgaact cgcggccgga acccgcagat tcttccgcag
    20281 acgccggcgt caaccacaca tcgtccgcgg ttacttcggc ggctcacgcg tccgctacgt
    20341 cctcgacgag aaccctttga gtttctgatc aatagcgtca accgctgttc cccgaggccg
    20401 tactcggagc cgcctgccgt tgctgactgc ggccgcagcg ggtgcgtagc tcggctgcat
    20461 gctcagggca gcggcctcgg tgctggaacc tggctgggcc tggagggtcg ccgtcgtgcg
    20521 gtacgtgggg gcgtgcagga attgcagccg tatgccgatg ggtcgaggct gagaatccac
    20581 ggatcggagt agctatgggc aatctggtcg tcgtcgaggt ggatggctcg tccacgagtc
    20641 tcaccgccgc ggaggcagcc gccgcagcgg cagcacggcg atcgagaccg ctggtcggag
    20701 agaaaaccgc cgtacacatc tccgacgctg ccggtcagca tggatgccac caggcggccg
    20761 ctcgcgatgc gagcctcgcc gcagtcgcct tggccgacct ttcccattcg tccagcggcg
    20821 tccgaccgat tactgcccgc ggctctcgat cccccagctc gggctgccgg gtcgcggcgc
    20881 acagcaccac tgcctcgggt gagaatgcct cgccaaggat cgcctggaag acctccagta
    20941 gcgctttcgc ggcatgactg ggcgatgacg ggtacgtcgg gttctcgaac tgccacagcg
    21001 gcagccatgc ctcgcgccgg ccgagtaggc ccaccaggag accgttctgg atatccccgg
    21061 ccactcccgt ggtcgcctac accggcgaca gcatcacgaa gcccgggcga aaagcgcagg
    21121 gcgctcgctc gaagggctcc gcccccgcgc ccttcggatt gtgtcctgga ggtctcagcg
    21181 tgagtgggtc cctgtgcgga gactgatgaa caggcagtgg ccggggacct atctggacga
    21241 ccccctcctg cccctgctga cggcagcaga ggcccgggac gcggtcggct acatgcggct
    21301 gctggagacg ctcgacctca cgccccgcgg gcaggccgct ggccggctcg ccgcagacct
    21361 ggcccgacgg ctccccgccg actgagcgcg gcactggcac gtcagtcgag gatgccatca
    21421 gggtcgcgat ggtctgcagt agtgcggcgt cgagcgtgca gccgtcgacg gggcccgcga
    21481 gggagacccg catacggcgc gctggcagct tgccaaggct ctgcccaagc cgttggtggt
    21541 tgctgctcgc gctgctgcat caggatcgcc gggcagctcc ggaccggagc ccttggcgaa
    21601 gcccatgccg aagcccgagg cggacccgga ggagcgggag ctgcgcgaga tcaccgagca
    21661 ggtacgcgcc ctcacaccca ccaagcgcac ccgcctcacg ggcacgatcc agggcctgct
    21721 gcggcagtcg tagacccagg gctccaactg agcgccgagt acgtgcctgc ccggccgggt
    21781 actggtgcga aaccccgaac ctcccgtaca accattcgag ctgctcacaa gtctgagtcg
    21841 gacacggcat ctccgtgtcc gactcagact tgtgagggct ccaccttgcg gttccgttcc
    21901 acccgcagcc gtctcgccgc cgccatcacg gccgtactcg cggccaccgc ccttagcgcc
    21961 ggcacgctgg cgaccgcccc ggcggccttc gcgacgacgt cagcttcggc cgggcaggcc
    22021 gacgccacgc ttcccgtcta ccccgaggac tcctacctcg cgggtgcggg caccaccggg
    22081 ttcttcacgt acgactatga cgaggccgac agcatcacgg acctggtctg gacgccgtac
    22141 gacggaggag catcgaagcg gctccggcat ccgaagggcg gcggttacgc cctggtgggc
    22201 aacgacgtgg ccgtcgtcgg ggatgaaagc tggtccgcgg gcatgcggtc gatcaccttg
    22261 tggaacatgg ccgacccggc ggccccgggt gtggacatcg acctcggcgc gctaggcggc
    22321 agatacgtcg ccgcgctgag cccgaccagt gtgctcacga gcatccgaaa gggggacgac
    22381 acggaggaac tggtcgtcgt gaccaagaag gggaccacga cgaccactcg taaaatcacg
    22441 ggtctgccgg tggatgcgat cgagatagac ggctcgacgg tcctcggggg caccgttgtc
    22501 gtgaggtacg cggcgggtcc gccggacgcg cgaaccggcc accgggccct gatcgacgtg
    22561 gcggccggga cggtgaccga gaccttctcc tctgccgagg ccgggtacaa cagcgactgg
    22621 ggccacttga ctttctcggc ttcgcaggtg gcctgggtcg ccgagacgga tggccaccag
    22681 acgtacgtca cgtctgtcga ccgcacgacg ggcaaggaga agaagaccgt cctgggcgac
    22741 agcattgacg actggtgcta cgagctggtg ggcgactggc tggtgtacgg cgcctactgg
    22801 acgcccgtga aggccgtcaa cttggccacc ggcgagaccc gcgaactcga ggtcacagcg
    22861 acggagtcgg caccctccgc cgacggcagc gcggcgctgc ggggcagccg ggacgccgat
    22921 ggcgacggtc tgttccgtgt cgagcccggt gcggacggca ccccgacggt caccaaggtg
    22981 gcggagacgg gcacccgtct ggcgatcgac gaggttcacg tccccagcgc ggtgaacctc
    23041 gaccagaccg gcggcaaggt gaccctgggc tggacgcttt cgcgtgccga cgcctacctg
    23101 gacgtcacgc tcacgcacac cgcgacgggt agagaattca aaaagcgcct gaccgcgacc
    23161 ggcacccggt tctccttcga ctgggacggc gtcatcgccg gggccgacgc gccgaacggg
    23221 tcgtacgcga tcgaggccga ggcgacgctg ctcgacggca ccggcgagcc cgtctaccag
    23281 ggctggctca tgaacgtcgt ccgcacggtc aacccgcacg acttcacgaa caacggctcc
    23341 accgacgtcc tcgcccggga cgcctccggt gcgctgtggc gcgacgacct gcgtgaccgg
    23401 ccggtgggcg gccagatcaa gaccgccgga cgcaccaagg tgggctcggg ctggaacacg
    23461 tacaagcaga tcgaggccgt cggcaacatc gccggcagca cgcacggcga cctcatcgcc
    23521 ctcgacggta ccggcgtgct gtggcagcac cagggcaagg gcgacgggac cttcgccacg
    23581 cgcgtgaaga tcggcggcgg ctggggcatc tacaacaagc tcgccggtgg ctcggacctg
    23641 aacggcgacg gacgcgcgga cctgctcgcg acggacgccg ccggcgtgct gtggttctac
    23701 aggggcacgg gttcggccac ggccccgttc ggcacccgca caaaggtcgg cggcggctgg
    23761 agcatctaca accagctcac ggccgtcggc aacatcgcgg gcagcgcgta cggcgacatc
    23821 gtcgcgcgtg acgcggccgg tgtcctgtgg ctctaccagg ggcacggcac cggcttctcc
    23881 acgcgtttga aggtgggctc cggctggggc gccttctccc agctcgtggg cgctggcgac
    23941 gtgaatggcg acgggcggcc ggacctgatc gcgtacggat cgggcggcac ctacgtctac
    24001 cggtccaccg gctcggcgac ggcgccgttc acgcgcatga cgacgaacct ctacgcgggc
    24061 gagggcacca agttcaacag cgtgctctga ggccggcccg tgttttgcag cgactgcatg
    24121 cacgacttca ccaccccgga gcaggacgag tagagctgac tccggcagct gcagtggacc
    24181 ggtgaagtcg gctccgtgag ccgcaaggca ttggccaacg ctgccgagga gtgtgtgtag
    24241 atgcgcactc cccggcgata gcgtttcgac agtcgcaggc ctggtggaag cgccgttcgt
    24301 cgcggatgga cgagttcctc ggacagccag tgcgctcggg cctacctgcg cggtgcgcag
    24361 tcggcacgcc gagctgcgca cagaacagcc cccgcgccgc cacagcggct gagcagcacg
    24421 cggacggccc gagccaggaa acgagggtgg gtcagcgcct tcggcggcag cccatgtcca
    24481 cgacctgcag gtactgggtg ttcacggcgg cgtcgagcac ggcgcctcgg tgagcctgtc
    24541 ggcgacgcac ttctgcgcgc gatggccgcg agggtagggg ccgacgtggg gctgggcgag
    24601 gtcggcggcc gtggagagct gccgggctcc gtccacgacg gcttcgacga ggcggaagca
    24661 gtcccaggcg ggcttgcgca ggtcgggatt ggtgcggagg taggcgccga gcgagttggc
    24721 tgccagggcc gccagcgtca ggccctggcc gtagatcggg ttgcgggggc gcagggcagt
    24781 ctctagttgc agtacccgct gttcctaaga ggtcatctca tttggtgagt ctgcggtagc
    24841 agatgagggt gcaggcgatg ctggtgaagg cgaggaagcg gtcggccttg cattcgtagc
    24901 gacggtggag tcgtcggcat ccggcgagcc aggacatggt gcgttcgatg gcccagcggt
    24961 ggctgcccag tcgctgcgag gactcgacgc ccttacgggc catgcggtgg gcgatgccgc
    25021 gctcgcacag ccatcgctgc aggtgggagt agttgtagcc tttgtcaccg tggagcttgc
    25081 cgggcttgcg tcgccgacgt ccgcggtggg agcggatcgg tgggatgccc ttggcggcgg
    25141 gatcagggcc tggctgtcat gcaggttcgc cgccgagatt gcgacagtga tgggcagacc
    25201 cgtccgctcg gtgatcaagt gaattttcga cccgtacttg ccccggccga ctggattcgg
    25261 acctgtcagg tccccctttt cagggcccgc atgttcaccg agtcgatcgc gcagcgggac
    25321 cagtccagct cgcctcggga cccgagatcg tcgaggacca gacggtagag cttggcccac
    25381 accctggcct tcgtccactc agagaagcgc agcgggaagt tcaccgtcat gaacatctgc
    25441 gtcaggaacc cgactctgaa cgtctacggt ctcttcacct gagacccttc gggttgatca
    25501 ccgccggggg agaagtgggc agccacttct cccccggctt tcattaccat cggaaggcaa
    25561 cgatgatgtc gaatttctcg gactggcagg accggatgct gcgagcggtc tggcggcacg
    25621 gggagcaact ccccgaggag gtgctgacgt ggatggccga gctgtacggc gagcgtggag
    25681 aagttccgga accggagttc tgtgaatcct ggaccgcgcg aaccttctcc atggcgagat
    25741 cagcgttcga gacggtcacc aagtcggcgg agcaggacac cggaaaagcg accaccggcg
    25801 acgacttcac ctacatcaca tacgttcgcg acccggaact gggaccggtc ggcgtggtcc
    25861 acatcaagtc ggcggaggtc tccacacccg attcggaaga ggttctgtgt gctgtgacag
    25921 aaggagtgca ggaattcgtc atgagccacc atcgcgtgac ctggccggtc tgcggcgagc
    25981 acggccgcgg tctgcatgta ggttacgtcc atgagacccc ggtctggaca tgcacgggcg
    26041 ggaccacgga tggtcacgtg gtgagagcga ttgatcccgc cgttcagctg tagatcatcg
    26101 cgggaccttt ctcggggtca gccacctctc accatgattt cccactgttc tccgcgtgat
    26161 ccggtgcgct tgtggtactc ccggccatga ccggaggtca tccctgagcc ttttccaagc
    26221 ctatggtgtc gaccgcgagc tggacacgca tgcgtcacca cgaagctcct ggcagacggg
    26281 ttctcaacca agatcacccg tgtctgccag gagcttcccg tacttgtcca cccatcctcg
    26341 gtcgatctgt cccatcgcac cctgcggttc ctgaccgggc ggcagaaggc cgggcggaag
    26401 gagatcggga cacgttggcg gcgtcttccc gccgcaggtc aagccctgct cgccc
//
