LOCUS       NZ_CP059991            20714 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces gardneri strain ATCC 15439 chromosome, complete genome.
ACCESSION   NZ_CP059991
VERSION     NZ_CP059991.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces gardneri
  ORGANISM  Streptomyces gardneri
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Genome-scale analysis on the transcription unit architecture of
            Streptomyces venezuelae ATCC 15439
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Biological Sciences, KAIST, 291 Daehak-ro,
            Yuseong-gu, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 6.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP013129
            Genome Coverage                   :: 187.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015710995.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 17:12:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,199
            CDSs (total)                      :: 8,101
            Genes (coding)                    :: 7,918
            CDSs (with protein)               :: 7,918
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 70 of 184
            Pseudo Genes (incomplete)         :: 147 of 184
            Pseudo Genes (internal stop)      :: 16 of 184
            Pseudo Genes (multiple problems)  :: 48 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:23:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2457174
            Orig. end                         :: 2477888
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059991.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20714
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="11"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20714
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20714
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10714](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10714
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            701..2071
                     /db_xref="GeneID:95689112"
                     /locus_tag="H4W23_RS11090"
                     /old_locus_tag="H4W23_11085"
     CDS             701..2071
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95689112"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103550.1"
                     /locus_tag="H4W23_RS11090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11085"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_055643962.1"
                     /sec_met_domain="DAO (E-value: 3.9e-08, bitscore: 32.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSTASTAQRTDVGETVDVVIVGAGIAGLTAARRLTGAGLSVAVL
                     EAEPQVGGRMATDSVDGFLLDRVGPLLTLSPEELRAVPGLDGLALRPFAPGVLVHSDGR
                     YARWGAPHPRRAGGAHRGGGHRSVGGAFSVARALASAPRRPTASLDQARLGASLVRLAA
                     TPSQRLLARPERTAREALTARLPARTVQGVLRPLLAALLGDPDLGTSSRRADLALRAFA
                     RGRLAVPEGGSAALPERLAASLPPGTVRTGVRVTEASVSRVTTAEHGVFGCRSVLLATG
                     ARTAAELLPGLRAPAFHAVTVLHHTAPAAPTGDPALLLESDPGGPVAHTAVMSAVDPVR
                     APEGRALITSTVLGAPPDDTERRVRKHLATLYGTSTDEWELLALHHTPEAVPAMPPPYD
                     ARRPVRLLAGLYVCGDHRDAGTPQGALASGARAARALLGDLGVRLPQEEEETAEEAA"
     gene            complement(2472..4043)
                     /db_xref="GeneID:95689113"
                     /locus_tag="H4W23_RS11095"
                     /old_locus_tag="H4W23_11090"
     CDS             complement(2472..4043)
                     /codon_start=1
                     /db_xref="GeneID:95689113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949915.1"
                     /locus_tag="H4W23_RS11095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11090"
                     /product="hypothetical protein"
                     /protein_id="WP_055643961.1"
                     /transl_table=11
                     /translation="MTERPPQRIPNRQLAALIAEAGFSNAGLARRVDQLGLEHGLDLRY
                     DKTSVTRWLRGQQPRGTTPALIAEVFTRRLGRRLSAQDLGLDACAPVYAGLEFAATPEE
                     AVDIVSGLWRKDSGSHAELRKIAFTPAGLVVPSRDWLIGRADDRVARGDLAPGPPSSRS
                     HTGAPGDPRAPHEPHARPDLRSPHEPRVPNDPRVAQHDPRVPPQGRFSVPRQRGTDRGP
                     GQRVSSGDIAALRSVGELFRTLDHAYGGGHARQALVRYLEHEAEPMLRGTYGESVGRRL
                     FAAAADLTRLAGWTSYDIAAHGLAQRYFVQALRLAQAAGDRAYGSYVLLTMSCQAVYLG
                     HGREAVQLARVAQQGVGPAAPPVVQAMLHAIEARGHAVLGEARVCGASLVRAERALEAA
                     RPGDEVPYWARMFDEAQLADELGHCHRDLQQYRPAAQHAERALQLRAPGFARSRLFCRV
                     VLATSRLALGELDQACALGAEAAQQASEMRSARAVEYVRDFERRLEPYRDAAAARTYRD
                     RVAAIG"
     gene            4401..5210
                     /db_xref="GeneID:95689114"
                     /gene="lipB"
                     /locus_tag="H4W23_RS11100"
                     /old_locus_tag="H4W23_11095"
     CDS             4401..5210
                     /EC_number="2.3.1.181"
                     /GO_function="GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95689114"
                     /gene="lipB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130127.1"
                     /locus_tag="H4W23_RS11100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11095"
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="WP_055646357.1"
                     /transl_table=11
                     /translation="MSELRFVRLGFGAEAVEYQVAWDKQREVHAARFADETPDTCLLLE
                     HPPVYTAGRRTAESERPLDGTPVVDVDRGGKITWHGPGQLVGYPIMKLPRPVDVVAHVR
                     RLEEALIRTAAEFGVETSRVEGRSGVWVLGDPVEQRPSLGGLSLDFDPRLTDEEFDPRL
                     NGPEYAPSNAGQRREDRKLAAIGIRVAKGVTMHGFALNVNPDNTWFDRIIPCGIRDAGV
                     ASLANELGRDLTIEEVLPVVERHLREVLEQAELKPREIERPAEPASV"
     misc_feature    complement(4409..4427)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            5358..6326
                     /db_xref="GeneID:95689115"
                     /gene="lipA"
                     /locus_tag="H4W23_RS11105"
                     /old_locus_tag="H4W23_11100"
     CDS             5358..6326
                     /EC_number="2.8.1.8"
                     /GO_function="GO:0016992 - lipoate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95689115"
                     /gene="lipA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018545494.1"
                     /locus_tag="H4W23_RS11105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11100"
                     /product="lipoyl synthase"
                     /protein_id="WP_055643960.1"
                     /sec_met_domain="PF04055 (E-value: 5e-12, bitscore: 45.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVAPDGRKMLRLEVRNAQTPIERKPEWIKTRAKMGPEYTKMQG
                     LVKSEGLHTVCQEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPEALDRDEP
                     RRVGESVVTMDLNYATITGVARDDLEDGGAWLYAETVRQIHQQTAERADGRTKVELLAP
                     DFNAVPELLKEVFDSRPEVFAHNVETVPRIFKRIRPGFRYERSLDVITQARDYGLVTKS
                     NLILGMGETREEVSEALRQLHDAGCELITITQYLRPSVRHHPVERWVKPQEFVELKEEA
                     DEIGFSGVMSGPLVRSSYRAGRLFQQAIEKRGAVDNATQAV"
     misc_feature    complement(6346..6361)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
     misc_feature    6489..6504
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    6500..6515
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    complement(6500..6517)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     gene            6604..6819
                     /db_xref="GeneID:95689116"
                     /locus_tag="H4W23_RS11110"
                     /old_locus_tag="H4W23_11105"
     CDS             6604..6819
                     /codon_start=1
                     /db_xref="GeneID:95689116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238898.1"
                     /locus_tag="H4W23_RS11110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11105"
                     /product="hypothetical protein"
                     /protein_id="WP_055643959.1"
                     /transl_table=11
                     /translation="MPAASTHVRVTAIPSVTDALKAVEALLLGAGQRTARRNAWTSVLE
                     DRRHAKDRVEAQIVMEAASGHASRAT"
     gene            6830..7534
                     /db_xref="GeneID:95689117"
                     /locus_tag="H4W23_RS11115"
                     /old_locus_tag="H4W23_11110"
     CDS             6830..7534
                     /codon_start=1
                     /db_xref="GeneID:95689117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511895.1"
                     /locus_tag="H4W23_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11110"
                     /product="DUF4191 domain-containing protein"
                     /protein_id="WP_055643958.1"
                     /transl_table=11
                     /translation="MARKANTGSADAANQGRLKQIALTYKMTRKADPKVGLVVAGVGIV
                     VLGVLLAIGFLIGHPVYLGILGFVLALLAAAIVFGRRAERAAFGQMEGQPGAAAAVLQN
                     VGRGWTTTPAVAMNRSQDVVHRAVGRAGIVLVAEGNPNRVKTLLAAEKKRMSRVVVDVP
                     VHDLIVGDGEGQVQLKKLRTTMLKLPRVLTGPQVTAANDRLRAMGDLMSNMPLPKGPMP
                     KGMKMPRGGKMR"
     gene            complement(7648..8115)
                     /db_xref="GeneID:95689118"
                     /locus_tag="H4W23_RS11120"
                     /old_locus_tag="H4W23_11115"
     CDS             complement(7648..8115)
                     /codon_start=1
                     /db_xref="GeneID:95689118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238900.1"
                     /locus_tag="H4W23_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11115"
                     /product="RDD family protein"
                     /protein_id="WP_055643957.1"
                     /transl_table=11
                     /translation="MDNRQALGSWLSGPRAAAEQAGVDFGYRGQQLGLPEEGPGSIARP
                     GRRLGALAVDWALCLLIAYGLITDSYSQATSNWALGLLLVLSVLTVGTIGSTPGKRLFG
                     LVVVSANGGRLSLWRVVVRSVLVCLAVPALIWDRDGRGLHDRLSGAVQVRI"
     misc_feature    complement(8200..8217)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.63"
                     /tool="antismash"
     gene            8337..9761
                     /db_xref="GeneID:95689119"
                     /gene="glnA"
                     /locus_tag="H4W23_RS11125"
                     /old_locus_tag="H4W23_11120"
     CDS             8337..9761
                     /EC_number="6.3.1.2"
                     /GO_function="GO:0004356 - glutamine synthetase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95689119"
                     /gene="glnA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033068.1"
                     /locus_tag="H4W23_RS11125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11120"
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="WP_055643956.1"
                     /transl_table=11
                     /translation="MSEKHGFQNADEVKKFIKDNDVKMVDVRFCDLPGVMQHFTIPATA
                     FDPAEELAFDGSSIRGFQAIHESDMALRADLSTARVDPFRRDKTLNINFFIHDPITGEA
                     YSRDPRNIAKKAETYLASTGIADTAYFGPEAEFYVFDSVRFETSANQGFYHIDSEAGAW
                     NTGSEENNRGYKVRYKGGYFPAPPVDHFADLRSEMSLELENVGLQVERQHHEVGTAGQA
                     EINYKFNTLLASADDLMLFKYIIKNVAWRNGKTATFMPKPIFGDNGSGMHVHQSLWANG
                     DPLFYDETGYAGLSDTARYYIGGILKHAPSLLAFTNPTVNSYHRLVPGFEAPVNMVYSQ
                     RNRSAAMRIPITGSNPKAKRVEFRAPDPSSNPYLAFSALLLAGLDGIKNKIEPAEPIDK
                     DLYELAPEEHANVQQVPTNLEAVLHALEDDNEYLQAGGVFTSDLIETWIDYKRTHEIAP
                     IQLRPHPHEFELYFDL"
     misc_feature    complement(9868..9881)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    9900..9913
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.93"
                     /tool="antismash"
     gene            10001..10714
                     /db_xref="GeneID:95689120"
                     /locus_tag="H4W23_RS11130"
                     /old_locus_tag="H4W23_11125"
     CDS             10001..10714
                     /codon_start=1
                     /db_xref="GeneID:95689120"
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033069.1"
                     /locus_tag="H4W23_RS11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11125"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_079037646.1"
                     /sec_met_domain="CDPS (E-value: 2.7e-87, bitscore: 290.9,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAAFAPAETLRLQPYTDHCRVIADEGAHVVIGVSPGNSYFTAQ
                     RLRELTRWGLDHFDQVDLVYTDLHVADMYEALGYAADEARRKAVKNLRGVRAKVGAAVA
                     EADPTGVRVRARGMSEFQALPAYQELHRQVVAAVDEDPVVRETCDALTGIFLAGKLAPG
                     QEPSSLQKEVCRAYISAEVPLFLDTPAILGVPSSLNCYHQALPLADLLYARGTGLRASR
                     NQGHGILTPVEGDSR"
     gene            10711..11907
                     /db_xref="GeneID:95689121"
                     /locus_tag="H4W23_RS11135"
                     /old_locus_tag="H4W23_11130"
     CDS             10711..11907
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95689121"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033070.1"
                     /locus_tag="H4W23_RS11135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11130"
                     /product="cytochrome P450"
                     /protein_id="WP_055643954.1"
                     /sec_met_domain="p450 (E-value: 4.6e-14, bitscore: 50.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVMTNELPAFPFDWDGTRLPAEIEALRAEPVRKVRTIAGAEAW
                     LVSSYELCRHVLEDPRFSLKDTSAPGVPRQYALTIPPHVVNNMGNITGAGLRKAVMKAI
                     NPKAPGLEEWLRARAGSLVDALVAEGAPGDLRSAYADPYSAGLHCRMLGIPEEDGARLL
                     RSLDVAFMNAPHEIEAARLHWDRDIAYMTERLDDPATGGLMAELAALREDPEYAHLTDE
                     MLATVGVTLFGAGVISTAGFLAMALVSVLTRPDVREALTASGAGGVAGAMDELLRVNLS
                     IGDGLPRLALEDVRLGEVDVRAGELVLVLVEAANHDPEHFPDPLAFRPDRENAAEHLSF
                     GGGRHYCPATALGKRHAEIALETLLDRLPGLRLAVPVEQLVWRTNFMKRLPERLPVAW"
     gene            complement(11969..12244)
                     /db_xref="GeneID:95689122"
                     /locus_tag="H4W23_RS11140"
                     /old_locus_tag="H4W23_11135"
     CDS             complement(11969..12244)
                     /codon_start=1
                     /db_xref="GeneID:95689122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238903.1"
                     /locus_tag="H4W23_RS11140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11135"
                     /product="hypothetical protein"
                     /protein_id="WP_024758496.1"
                     /transl_table=11
                     /translation="MALAVIRTPSLEPWKPLQRKPLPAGRPREWYVTHNRRLKAMRLAI
                     ALLDAGVYVPSKATNATIRTTAADIGIHPPSDTTCRMVRALIRYGR"
     gene            12394..12753
                     /db_xref="GeneID:95689123"
                     /locus_tag="H4W23_RS11145"
                     /old_locus_tag="H4W23_11140"
     CDS             12394..12753
                     /codon_start=1
                     /db_xref="GeneID:95689123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885700.1"
                     /locus_tag="H4W23_RS11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11140"
                     /product="arsenate reductase family protein"
                     /protein_id="WP_055643953.1"
                     /transl_table=11
                     /translation="MEIWINPACSKCRSALTLLDAEGADYTVRRYLEDVPSPAEIGQVL
                     DRLGLEPWDITRTQEAVAKELGVKEWPRDEANRDRWIEALAEHPKLIQRPIITAEDGTA
                     VVARSEEAVRDALSR"
     misc_feature    complement(12397..12410)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     gene            12815..14275
                     /db_xref="GeneID:95689124"
                     /locus_tag="H4W23_RS11150"
                     /old_locus_tag="H4W23_11145"
     CDS             12815..14275
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (265-439). E-value:
                     8.7e-09. Score: 26.9. Matches aSDomain:
                     nrpspksdomains_H4W23_RS11150_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GeneID:95689124"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033075.1"
                     /locus_tag="H4W23_RS11150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11145"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_055643952.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-06, bitscore:
                     26.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTVDAGPGGLGVDLHLELGASGSRRAVLTEALREAVRGGRLAP
                     GTLLPPYRSLAADLGIARNTVADAYAELVAEGWLTSRQGSGTRVAERVLAPAPGPARPA
                     APAALPYDLVQGKPDPGAFPRAAWLAAARRALTAAPHEAFGVGDPRGRIELRRALAAYL
                     ARVRGVRTTPDRIVVCSGTAHALRLLARVPLATHAREKPARQTAARKAPPRPWAVEAYG
                     LPYHQGLLGEAGIHTLPLAVDEDGARIAEIPPEAGTVLLTPAHQFPTGGPLHPERRAGV
                     LEWARRSGGLVVEDDYDGEFRYDRRPVGAVQSLDPDRTVLLGSVSKSLSPALRIGWMCL
                     PEALVDGVVEAKGLREPHTSATEQLTLAEFVDSGAYDRHVRRMRQHHRVRRDRLATVLA
                     ERVPRVRVTGLSAGLHALVELPPGTERSAVAAAARHGVAVEGLADYRHPEALGPALPDG
                     LVVGYATPPDRLYPATLDALCQALAAAL"
     aSDomain        13610..14131
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H4W23_RS11150_Aminotran_1_2.1"
                     /evalue="8.70E-09"
                     /label="H4W23_RS11150_Aminotran_1_2.1"
                     /locus_tag="H4W23_RS11150"
                     /protein_end="439"
                     /protein_start="265"
                     /score="26.9"
                     /tool="antismash"
                     /translation="QFPTGGPLHPERRAGVLEWARRSGGLVVEDDYDGEFRYDRRPVGA
                     VQSLDPDRTVLLGSVSKSLSPALRIGWMCLPEALVDGVVEAKGLREPHTSATEQLTLAE
                     FVDSGAYDRHVRRMRQHHRVRRDRLATVLAERVPRVRVTGLSAGLHALVELPPGTERSA
                     VAAAARHGVAV"
     gene            complement(14251..15171)
                     /db_xref="GeneID:95689125"
                     /locus_tag="H4W23_RS11155"
                     /old_locus_tag="H4W23_11150"
     CDS             complement(14251..15171)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95689125"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033076.1"
                     /locus_tag="H4W23_RS11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11150"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_055643951.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.6e-22, bitscore:
                     79.3, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 4.6e-07,
                     bitscore: 28.8, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKDLGAKPRIGLLGTGPWAGRTHAPALAGHPGVEFSGVWGRRAE
                     AAEELAAASGTRAYEDVDALFAASDAVAFALPPDVQAPLAVRAARAGCHVLLDKPVATT
                     VAAAREVAEAAEEAGVASVVFCTLRFAEETARWIEERKAAGGWFLGEAHWLGSLYGAGS
                     TSVYADSPWRREKGGLWDVGPHVLSVYLPVLGDVTAITAAAGPEDTHHLVLRHSSGASS
                     TATLTLSAPPEAAEVTLSLHGAAGRAELPRWGGALEAFGTAVDALLTAVRTGEPHPCDA
                     RFGLRLTEILTEAERLAAQSAAAKA"
     gene            15170..16768
                     /db_xref="GeneID:95689126"
                     /locus_tag="H4W23_RS11160"
                     /old_locus_tag="H4W23_11155"
     CDS             15170..16768
                     /codon_start=1
                     /db_xref="GeneID:95689126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238906.1"
                     /locus_tag="H4W23_RS11160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11155"
                     /product="hypothetical protein"
                     /protein_id="WP_230883290.1"
                     /transl_table=11
                     /translation="MPPVCRVPLTADAARARNPVAGLPPSGVSVDPPAAGLRCDFRNLP
                     MKQRLRCSYPHSPAGAHEKGRALSELVAAEDVLLFVNAAVTATGQREFRSSAAAQHFSL
                     RFVHEYVRVNYRPVYAAALALDINHHNAALIVEQLLRTPHEAGGSEAKRAEGRLIAARL
                     ALLPPQRVYRLFRSLRAAGVNNRRTRAIVRAWLAARPDPALDAVKYRPGLKAALRHVHG
                     RPADEETGDFLFAPGRRVRYGNATLDAYRRAHYEQGALYELPFTVAEGFAARHKVPRAV
                     FLERIAPRMTRLEQLRTARAADLTVMPLTRLALYVLSLPFAERVERRAELTHALRAAAR
                     RAAGPHAGSWGRVAAVLDDSFSSSGSAVKRRRPLAVALGCHFLLEALAAPGAYTPLWTS
                     GGSDPLLVRPYGPTPLGLRILDALETGPDRVVIVSDGWDNAPPGLAGEVLRVWRTRLDA
                     ERRTSIVHLNPVYDAEGFDVRRLAPSVPTAGIRDAEDLAALVEIAQFAEGRTGFAELGA
                     YLDRRVELFLKEAGG"
     gene            16765..17940
                     /db_xref="GeneID:95689127"
                     /locus_tag="H4W23_RS11165"
                     /old_locus_tag="H4W23_11160"
     CDS             16765..17940
                     /codon_start=1
                     /db_xref="GeneID:95689127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238907.1"
                     /locus_tag="H4W23_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11160"
                     /product="ARPP-2 domain-containing protein"
                     /protein_id="WP_055643949.1"
                     /transl_table=11
                     /translation="MTRIDLTGLDVRPAQVWGGVRIVPLVRAEPVAGLRLRRELYEGSG
                     LATVDLGDRTTYTSYVPHGFVADWTGPGTGAGAEQGVESAAYGTLLGGEGAPPCVPVRR
                     VHRLAKRRQGERRLRFLPLHLALDGYLALHFGGPSVVWDDWSRKALGQGLSPRAEAAYA
                     GWAVPGLGEALRIFELHPGQCGLLLYVADALAAAFVVPHPDDYRVLHPTLVEDLYGELV
                     HQYAYYGAQVPEFTARIRDGVGGIRTLADLRAAARQEERAWAEAHDGLMARDLLETSYA
                     FERVYRMGDFDLFRFLPPFLRDGREQHIGELITDHKGRAAYLKTFRLSEKQIRKGHLLR
                     LLADRDWLLEATAEALGTTYAEVVRRIEAAGLGGLLDAHVVARRTREKEEG"
     misc_feature    complement(17941..17958)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(17952..17969)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.81"
                     /tool="antismash"
     gene            18083..19114
                     /db_xref="GeneID:95689128"
                     /gene="glnII"
                     /locus_tag="H4W23_RS11170"
                     /old_locus_tag="H4W23_11165"
     CDS             18083..19114
                     /EC_number="6.3.1.2"
                     /codon_start=1
                     /db_xref="GeneID:95689128"
                     /gene="glnII"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989747.1"
                     /locus_tag="H4W23_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11165"
                     /product="glutamine synthetase"
                     /protein_id="WP_055643948.1"
                     /transl_table=11
                     /translation="MTFKAEYIWIDGTEPTAKLRSKTKIIVSGGTALDELPIWGFDGSS
                     TNQAKGHASDRVLKPVFVCPDPIRGGDDILVLCEVLNTDMTPHESNTRAALAEVAAKYA
                     AQEPIFGIEQEYTFFDGERPLGFPVGGFPAPQGGYYCGVGADEIFGRDIVEAHLENCLT
                     AGLGISGINAEVMPGQWEFQVGPLAPLTVSDQLWIARWLLYRTAEDFKVSATLDPKPVK
                     GDWNGAGAHTNFSTKAMREGYDAIITAAESLGEGSKPLDHVKNYGAGIDDRLTGLHETA
                     PWDKYSYGVSDRGASVRIPWQVEQDQKGYIEDRRPNANVDPYVVTRLLVDTCCEALEKA
                     GQV"
     misc_feature    18132..18146
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.47"
                     /tool="antismash"
     misc_feature    19233..19246
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            19319..20488
                     /db_xref="GeneID:95689129"
                     /locus_tag="H4W23_RS11175"
                     /old_locus_tag="H4W23_11170"
     CDS             19319..20488
                     /codon_start=1
                     /db_xref="GeneID:95689129"
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019055750.1"
                     /locus_tag="H4W23_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_11170"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_055643947.1"
                     /transl_table=11
                     /translation="MKLVVRVKLLPTPEEAAALEATLRACNEAASCVSVRAFESGRTSR
                     AALQALAYAELKARGLSAQPALHVLRKVADAYTALRASLKAGSLGRRVSKRYRGVAGKP
                     VVFRPDAAQPFDDRCLSWQLDKRTVSIWTTSGRMKGLAFTGQAEQLAMLTAYRKGETDL
                     LCQGGAWYLVATCEVPEAAPNTAPAGFVGVDLGIVNIATTSAGTRHSGRRLNRRREADR
                     RLRAKLQKKGTKSAMRRAKRHAGKEARRARDINHKISKCIVAEAERTGRGIALEDLGGI
                     RERVRLRKPQRVTLHSWSFRQLGTFIAYKAQRAGVPVVYIDPAYTSQECSRCHHVDRRN
                     RPSQAVFACQACGFVEHADLNSSHNIAARGWWTWVRGAESQAPALTLTV"
     gene            20582..20704
                     /db_xref="GeneID:95695051"
                     /locus_tag="H4W23_RS41600"
     CDS             20582..20704
                     /codon_start=1
                     /db_xref="GeneID:95695051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238909.1"
                     /locus_tag="H4W23_RS41600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_099054277.1"
                     /transl_table=11
                     /translation="MATTKNETATGRDDLEPFWPSRQHDDFDRVCCRARNASAL"
ORIGIN
        1 cgcgcccgca gggacgggct tcctgccctc ggtgtgcgtg gagtgggagg ccgcctcggc
       61 ccccgccgag gaggccggca tccgcgtcgc gtacgcccgc accggtctgg tcgtggcccg
      121 cgagggcggt gcgtgggggc ggctcttccc ggtcttccgc gccgggctcg gcgggcggat
      181 gggcgacggc cgccagtact ggtcccacat ctccctccac gacgaggtgg ccgccctgcg
      241 ccacctggtc gacaccccgg gcctgtcggg cccggtgaac ctgacggccc ccgagccggt
      301 caccaaccgg gaggtgacgg ccgcgatggg ccgggtcctg cggcggccga ccctgttcac
      361 ggtcccggcg cccgccctga agctggcgct cggggacttc gcccaggacg tgctgggcag
      421 tcagcgggtg ctgccggggc ggctgttgga gtccggcttc gacttcgcct tcccgacgat
      481 cgacgaggcg atccgggccg cggcccgctg acacacccct cccaccggct ccctgcgctc
      541 ccccgtgctg cgtgcacccc gccgcgcgcg ggccgacttc cgtgggcgcg ctccctaggc
      601 tcgatgccca ttgttcgata cgaccgcgaa cgcgggcatt ccgggggcct gttgggggca
      661 taaggcctcc caccggcggc gccgacctgg ggaggggcac gtgctcagta ccgcaagtac
      721 cgcacagcga acggacgtcg gggaaaccgt cgacgtcgtc atcgtggggg ccgggatcgc
      781 ggggctcacc gccgcccgcc ggctgaccgg ggccgggctc tccgtcgccg tcctggaggc
      841 ggagccgcag gtgggtggcc ggatggccac cgactccgtc gacggcttcc tgctcgaccg
      901 ggtaggcccc ctgctcaccc tgtcgcccga ggaactgcgg gccgtgccgg ggctcgacgg
      961 cctcgcgctc cgtcccttcg cccccggggt cctcgtgcac agcgacggcc ggtacgcccg
     1021 gtggggcgcc ccgcacccgc gccgggcggg cggcgcgcac cgaggcgggg ggcaccggag
     1081 cgtgggggga gcgttcagcg tggcacgcgc cctcgcgagc gccccccggc gtccgacggc
     1141 ctcgctcgac caggcgcggc tcggcgcgtc cctggtccga ctcgccgcga ccccgtcgca
     1201 gcggctgctc gcccgccccg agcggacggc gcgcgaggcg ctgaccgccc ggctgcccgc
     1261 ccggaccgtg cagggcgtgc tgcgaccgct gctcgcggcg ctcctcggcg acccggacct
     1321 cggtacgtcg agccgccgcg cggacctggc gctgcgcgcc ttcgcccggg gccggctcgc
     1381 cgtaccggag ggcggctcgg cggccctccc ggaacggctc gccgcctcgc tgccgcccgg
     1441 cacggtccgt accggcgtcc gggtcacgga ggcatccgtc tcccgggtga cgaccgccga
     1501 gcacggggtc ttcggctgcc gctcggtgct gctcgcgacg ggggcgcgga cggcggccga
     1561 gctgctgccc ggcctgcggg cgcccgcctt ccacgcggtg acggtcctgc accacacggc
     1621 gcccgcggcg cccaccgggg acccggcgct gctcctggag tccgacccgg gcgggccggt
     1681 ggcccacacg gccgtgatga gcgcggtcga cccggtccgc gccccggagg gccgggccct
     1741 gatcacctcg acggtgctcg gggcgccgcc ggacgacacg gagcgccggg tccgcaagca
     1801 cctcgccacg ctgtacggca cgtcgaccga cgagtgggag ctgctggccc tgcaccacac
     1861 tccggaggcc gtgccggcga tgccgccgcc gtacgacgcc cgccgcccgg tccggctgct
     1921 cgcgggcctg tacgtgtgcg gcgaccaccg ggacgcgggc acgccgcagg gcgccctcgc
     1981 ctcgggggcg cgcgcggccc gcgcgctcct cggcgacctc ggcgtccggc tcccgcagga
     2041 ggaggaagag acggcggagg aggccgcgta acgcctacgc ggacgcggcc ccggcccggg
     2101 ccacgggctc cgagccgggc tctggctcgg ggctccgggc tccgagctcc cggctgcggg
     2161 ctccggctcc ggctccggct ccgggctccg actccgagct cccggctccg gctccgggct
     2221 ccgactccga gctcccggct ccgggctccg actccgagct ccgggctccg gctccgggct
     2281 ccgactccgg ccggaggttc gggccaggcg ctggcccgag cgcacggccc cgactccggc
     2341 ccgggcctcg ggctcggggc ccggtcccgt gggctccggc cggaggctcg gggcccgggt
     2401 tcggctccgc tctgggactc cggcccgggg ctcgggctcg ggttcggctc cgtccctgct
     2461 ccggccccgg ctcagccgat ggcggccacg cggtcgcggt aggtgcgggc ggccgcggcg
     2521 tcgcggtacg gctccaggcg gcgctcgaag tcgcggacgt actcgacggc gcgcgccgac
     2581 cgcatctcgg aggcctgctg ggcggcctcc gcgccgaggg cgcacgcctg gtcgagttcg
     2641 ccgagggcga ggcgcgaggt ggcgaggacg acccggcaga agagccggct gcgggcgaag
     2701 ccgggcgcgc gcagctggag ggcgcgctcg gcgtgctggg cggcgggccg gtactgctgg
     2761 aggtcgcggt ggcagtgccc gagctcgtcg gcgagctggg cctcgtcgaa catcctggcc
     2821 cagtagggca cctcgtcgcc cggccgggcc gcttcgaggg cccgctcggc ccggaccagg
     2881 gaggcgccgc agacccgggc ctcgccgagg accgcgtgcc cgcgggcctc gatcgcgtgc
     2941 agcatcgcct ggacgacggg cggcgcggcg ggcccgacgc cctgctgggc gacccgggcg
     3001 agctgcacgg cctccctccc gtggccgagg tagacggcct ggcagctcat ggtgaggagc
     3061 acgtacgagc cgtaggcccg gtcgccggcg gcctgggcga ggcgcagcgc ctggacgaag
     3121 tagcgctggg cgaggccgtg ggcggcgatg tcgtacgagg tccagccggc gagtcgggtg
     3181 aggtcggcgg cggcggcgaa gaggcggcgg ccgacggact cgccgtacgt gccgcgcagc
     3241 atcggctcgg cctcgtgctc caggtagcgg acgagggcct ggcgggcgtg gccgccgccg
     3301 taggcgtggt cgagggtgcg gaagagctcg ccgacggagc ggagggcggc gatgtcgccg
     3361 ctggagaccc gctggccggg tccgcggtcc gtaccgcgct gccggggcac ggagaagcgg
     3421 ccctgcgggg ggacgcgcgg gtcgtgctgc gccactcggg ggtcgttcgg gacgcggggt
     3481 tcgtgcgggg agcgaaggtc gggccgtgcg tggggttcgt gcggcgcgcg gggatcaccg
     3541 ggcgccccgg tgtgggaccg ggaggagggc ggaccggggg cgagatcgcc gcgggcgacc
     3601 cggtcgtcgg cgcggccgat gagccagtcg cggctgggca cgacgagccc cgccggggtg
     3661 aaggcgatct tgcggagttc ggcgtggctg ccggagtcct tgcgccagag cccgctgacg
     3721 atgtcgacgg cctcctcggg ggtcgccgcg aactccaggc ccgcgtagac cggcgcgcag
     3781 gcgtcgagac cgaggtcctg cgcggagagc cggcggccga ggcgtcgggt gaagacctcg
     3841 gcgatgaggg cgggggtggt gccgcgcggc tgctggccgc ggagccagcg ggtcacggag
     3901 gtcttgtcgt accgcagatc gaggccgtgt tccagaccga gctggtccac tcgtctggcg
     3961 aggcccgcat tggagaaccc ggcttcggcg atgagcgcgg cgagctggcg gttcgggatg
     4021 cgctgcggtg gtcgttccgt catcagctgt gcggtctcct gccttccggg cccaggcgca
     4081 gcccgttcgg tccctcatgg aacggcgcga atttagcggt cctcacggcc cgtaccgcca
     4141 ccttcgcccc acattcatcc gatcgtgtga ggattgacgg caccgctgac gtagtcgccg
     4201 cggtccagct gacggaggcg gcacccccgc accgcccgta gggacgtccc cggcaccgcc
     4261 ctcgccgccg cccccggcac ccccgtacag gtgtgcgtgg tgtcgccgta cagtggcatg
     4321 ggcgcgaatg acgcatgtgc cgatccggcc cgggatgatc cccggtcccc ggtccccggc
     4381 acccaggagg aggcatggcc gtgagtgagc tgcgattcgt ccgccttggt ttcggcgcgg
     4441 aagccgtcga gtaccaggtg gcctgggaca agcagcgcga ggtgcacgcc gcgcggttcg
     4501 ccgacgagac ccccgacacc tgtctgctcc tggagcaccc gccggtctac acggctggcc
     4561 ggcgcacggc ggagagcgag cgcccgctgg acgggacgcc cgtcgtggac gtcgaccgcg
     4621 gcggcaagat cacctggcac ggccccggcc agctcgtggg ctacccgatc atgaagctgc
     4681 cccgcccggt ggacgtcgtc gcacacgtcc gccgcctgga ggaggcgctg atccggacgg
     4741 ccgccgagtt cggtgtggag acgtcccggg tcgaggggcg cagcggcgtc tgggtcctcg
     4801 gcgacccggt cgagcagcgg ccgtcgctcg gcgggctctc cctcgacttc gacccccgtc
     4861 tcaccgacga ggagttcgac ccccggctga acggccccga gtacgcgccg tccaacgccg
     4921 gccagcgccg cgaggaccgc aagctcgccg ccatcggcat ccgggtcgcc aagggcgtca
     4981 ccatgcacgg cttcgccctg aacgtgaacc cggacaacac ctggttcgac cggatcatcc
     5041 cctgcgggat ccgcgacgcg ggcgtcgcct cgctcgcgaa cgagctgggc cgggacctca
     5101 cgatcgagga ggtgctcccg gtcgtggagc gccatctgcg ggaggtcctg gagcaggcgg
     5161 agctgaagcc gcgcgagatc gagcgtccgg cggagccggc ctccgtctga ggcacggccc
     5221 gctcgggcac ggcctccaca ctgggggcac ggcctgagga atgcggggct ctggccatgg
     5281 gttggccaga ggtaaggcat gggaagcaac gggcgtaccc tggtgtgcgc cgaagaatcg
     5341 aagctacagg agccgatgtg tccgcagtcg cacccgacgg acgcaagatg ctgcgcctgg
     5401 aggtccggaa cgcccagacc cccatcgagc gcaagcccga gtggatcaag acccgcgcga
     5461 agatgggtcc cgagtacacg aagatgcagg gcctcgtgaa gagcgagggc ctgcacacgg
     5521 tctgccagga ggcgggctgt cccaacatct tcgagtgctg ggaggaccgc gaggcgacct
     5581 tcctcatcgg cggcgaccag tgcacgcggc gctgcgactt ctgccagatc gacacgggca
     5641 agcccgaggc gctggaccgt gacgagccgc gccgcgtggg cgagtcggtc gtcacgatgg
     5701 acctgaacta cgccacgatc accggcgtcg cgcgcgacga cctggaggac ggcggcgcct
     5761 ggctgtacgc ggagaccgtg cgccagatcc accagcagac ggcggagcgc gccgacggcc
     5821 gcacgaaggt cgagctgctg gcccccgact tcaacgcggt gccggagctt ctgaaggagg
     5881 tcttcgactc gcgccccgag gtcttcgcgc acaacgtcga gaccgtcccg cggatcttca
     5941 agcggatccg tccgggcttc cgctacgagc gctccctcga cgtcatcacc caggcccgcg
     6001 actacggtct ggtcacgaag tcgaacctga tcctcggcat gggcgagacc cgcgaggagg
     6061 tcagcgaggc gctccggcag ctgcacgacg cgggctgcga gctcatcacg atcacgcagt
     6121 acctgcgccc ctcggtgcgg caccaccccg tcgagcgctg ggtgaagccg caggagttcg
     6181 tggagctgaa ggaggaggcc gacgagatcg gcttctccgg tgtgatgtcg ggcccgctgg
     6241 tccggtcctc gtaccgcgcg ggccgcctct tccagcaggc gatcgagaag cgcggcgcgg
     6301 tcgacaacgc cacgcaggcg gtctgaccgc tccacggctc cgccgtgtga atccgagcac
     6361 aagcagttac cggtcagtaa tggccggatc ggacgcggcc cgtacgcccc cgcagctcag
     6421 cggggacgta cgggccgcgt cggcgttccc cggtggcgcg accggccgcg caaacgattc
     6481 atcagtgttt gaccaccggg tcacgccctg gtaacaccga tctgtgagcc tggattcact
     6541 caccgccacc accgctcgca tccccccgcc tcgtctcatc cgcaatcgag ggaggacccc
     6601 gacatgccgg ccgcatcgac gcacgtccgc gtcaccgcga tcccgtccgt caccgacgcc
     6661 ctgaaggccg tggaggccct gctgctcggc gccgggcagc gcaccgcccg gcgcaacgcc
     6721 tggacctccg tcctggagga ccgccgccac gccaaggacc gggtcgaggc ccagattgtg
     6781 atggaggccg cgtccggcca cgcttcccgg gccacgtaaa cttcaggaca tggcgaggaa
     6841 ggcaaacacg ggcagcgctg acgctgcgaa ccaggggcgg ctcaagcaga tcgccctcac
     6901 gtacaagatg acccggaagg ccgaccctaa ggtcggactt gtcgtcgcag gcgtgggcat
     6961 cgtcgtactc ggtgtcctcc tcgcgatcgg cttcctcatc ggtcatccgg tctacctggg
     7021 catcctgggc ttcgtcctgg cgctcctggc ggcggccatc gtcttcgggc ggcgcgccga
     7081 gcgcgcggcc ttcgggcaga tggagggtca gccgggcgcg gccgcggcgg tgctgcagaa
     7141 cgtcgggcgc ggctggacga cgacccccgc ggtcgcgatg aaccgcagcc aggacgtcgt
     7201 gcaccgcgcg gtcggccggg cgggcatcgt gctggtggcg gagggcaacc cgaaccgggt
     7261 gaagactctg ctggcggccg agaagaagcg gatgagccgc gtcgtggtgg acgtgccggt
     7321 gcacgacctc atcgtcggcg acggcgaggg ccaggtgcag ctgaagaagc tgcgcacgac
     7381 catgctcaag ctgccccgcg tgctcaccgg tccgcaggtc accgcggcca acgaccggct
     7441 gcgggcgatg ggcgacctga tgagcaacat gccgctgccg aagggcccga tgcccaaggg
     7501 catgaagatg ccgcgcggcg gaaagatgcg ctgagcggaa cgacgcgctg acgcgcccga
     7561 ccgaacacga ggagaagggc cccggaccac acggtccggg gcccttctcg ctgccggcgg
     7621 tcggccgggt cgctcgggtc ggaccggtca gatacggacc tggacggcgc cggagaggcg
     7681 gtcgtggagg ccgcggccgt cgcggtccca gatcagggcc gggacggcga ggcagacgag
     7741 cacggagcgg acgacgacgc gccagaggct cagccggccg ccgttcgccg agacgaccac
     7801 caggccgaag aggcgcttgc cgggcgtcga gccgatggtg ccgacggtca gcacgctcag
     7861 gacgagcaga agaccgagcg cccagttgct ggtcgcctgg ctgtagctgt cggtgatcaa
     7921 tccgtatgcg atcagaagac acagggccca gtcgacggcg agggcgccga gccggcggcc
     7981 cgggcgggcg atcgagccgg gtccctcctc ggggagtccc agctgctgcc cccggtatcc
     8041 gaagtccacg cctgcttgct ccgccgcggc acgggggccg gagagccacg atccgagtgc
     8101 ttgcctgttg tccacccgac cacggtactg cgcccgtttt cgatcacttc cgtccgggtc
     8161 ggcgtacgcg cgccacagcg cgccgcacac ccgctccggt taacttcgac gaaacaaatg
     8221 ggtcatgctt gagaaatccc gtctgcctat ggtcgggtcc agcgtgtgcc accgcactgg
     8281 ccgcacgacc gagctgcaac cccgcccctc cccgggccgg gagtaggagg agttggatgt
     8341 ccgagaagca cgggttccag aacgccgacg aggtcaagaa gttcatcaag gacaacgacg
     8401 tcaagatggt cgacgtccgg ttctgcgacc ttccgggcgt gatgcagcac ttcacgatcc
     8461 cggcgacggc cttcgacccg gcggaggagc tcgccttcga cggctcgtcg atccgcggct
     8521 tccaggcgat ccacgagtcc gacatggcgc tccgcgccga cctgtcgacg gcccgcgtgg
     8581 accccttccg ccgcgacaag acgctgaaca tcaacttctt catccacgac ccgatcacgg
     8641 gcgaggccta cagccgcgac ccgcggaaca tcgcgaagaa ggccgagacg tacctcgcct
     8701 ccaccggcat cgccgacacc gcgtacttcg gccccgaggc ggagttctac gtcttcgact
     8761 cggtgcgctt cgagacctcg gcgaaccagg gcttctacca catcgactcc gaggccggcg
     8821 cctggaacac cggttcggag gagaacaacc gcggctacaa ggtccgctac aagggcggct
     8881 acttcccggc cccgccggtc gaccacttcg ccgacctgcg ctcggagatg tccctggagc
     8941 tggagaacgt cggcctccag gtcgagcgcc agcaccacga ggtcggcacc gccggccagg
     9001 ccgagatcaa ctacaagttc aacacgctgc tcgcctcggc cgacgacctg atgctgttca
     9061 agtacatcat caagaacgtc gcctggcgga acggcaagac cgcgaccttc atgccgaagc
     9121 cgatcttcgg cgacaacggc tcgggcatgc acgtccacca gtcgctgtgg gccaacggcg
     9181 acccgctgtt ctacgacgag acgggctacg cgggcctctc ggacaccgcc cgctactaca
     9241 tcggcggcat cctcaagcac gccccgtcgc tgctcgcctt caccaacccg acggtgaact
     9301 cgtaccaccg cctggtcccg ggcttcgagg ccccggtcaa catggtgtac tcgcagcgca
     9361 accgctccgc cgccatgcgc atcccgatca cgggctcgaa cccgaaggcc aagcgcgtcg
     9421 agttccgcgc gccggacccg tcctcgaacc cgtacctcgc cttctcggcg ctcctcctcg
     9481 cgggcctcga cggcatcaag aacaagatcg agccggcgga gccgatcgac aaggacctgt
     9541 acgagctcgc tcccgaggag cacgcgaacg tccagcaggt cccgaccaac ctggaggccg
     9601 tgctccacgc cctcgaggac gacaacgagt acctgcaggc cggtggcgtc ttcacctccg
     9661 acctgatcga gacctggatc gactacaagc gcacccacga gatcgccccg atccagctgc
     9721 gcccgcaccc gcacgagttc gagctctact tcgacctcta ggccgtaccg cgcgagcgag
     9781 gttctcacga ggcccgtcgt cccctttcga gggggcggcg ggcctccgcc gttttccggc
     9841 caagatcacg aaacggggaa caggtgacga actttcgtac gtacctacga gtagggctgt
     9901 tcacgctccg cgactgatcg atagcgtgac gtcgtcgctg ccgccacacc cggagcacgg
     9961 ggctccgctg ggactagctg gcgcgatgag gactgcctac gtgactcagg cggcattcgc
    10021 ccctgcagag acgctcagac tccagccgta caccgatcac tgccgcgtca tcgccgacga
    10081 aggcgcgcac gtggtcatcg gcgtctctcc gggaaacagt tatttcaccg cccagcggct
    10141 gcgcgagctg acgcgctggg gcttggacca cttcgatcag gtcgatctcg tctacaccga
    10201 tctgcatgtc gccgacatgt acgaggcact ggggtacgcg gccgacgagg cacgacggaa
    10261 ggccgtcaag aacctgcggg gggtacgggc gaaggtcggg gctgccgtgg ccgaggccga
    10321 ccccacgggg gtacgcgtac gggcccgtgg gatgtcggag ttccaggccc tgcccgcgta
    10381 ccaggagctg caccgccagg tcgtggcggc cgtcgacgag gatccggtgg tacgggagac
    10441 ctgcgacgcg ctcaccggga tcttcctggc cgggaagctg gcgccggggc aggagccgag
    10501 cagcctccag aaggaggtgt gccgggcgta catcagcgcc gaagtaccgc tgttcctgga
    10561 cacccccgcg atcctcgggg tgccctcctc gctcaactgc taccaccagg ccctgcccct
    10621 cgccgatctg ctctacgccc ggggcaccgg gctgcgtgcc tcccgcaacc aggggcacgg
    10681 catcctcacg cctgtcgaag gagattcacg atgaccgcgg tcatgacgaa cgaactgccc
    10741 gcgttcccct tcgactggga cgggacccgg ctgcccgccg agatcgaggc cctgcgcgcc
    10801 gagccggtcc ggaaggtccg cacgatcgcc ggggccgagg cctggctggt ctcctcctac
    10861 gagctgtgcc ggcacgtcct ggaggacccg aggttcagcc tgaaggacac ctcggcgccg
    10921 ggagttccgc ggcagtacgc gctgacgatc ccgccgcacg tggtgaacaa catgggcaac
    10981 atcaccgggg ccgggctgcg caaggccgtc atgaaggcca tcaatccgaa ggcccccggc
    11041 ctggaggagt ggctgcgggc gcgggccgga tccctggtgg acgcgctggt cgccgagggg
    11101 gcgcccgggg atctgcggag cgcctacgcc gatccgtact cggcggggct gcactgccgg
    11161 atgctgggca tcccggagga ggacggagcg cggctgctgc gcagtctgga cgtggccttc
    11221 atgaacgcgc cgcacgagat cgaggcggcc cggctccact gggaccggga catcgcctac
    11281 atgacggagc gcctcgacga tccggcgacg ggcgggctga tggccgagct cgcggcgctg
    11341 cgcgaggatc ccgagtacgc gcatctgacg gacgagatgc tggcgacggt gggcgtgacg
    11401 ctgttcgggg ccggggtgat ctccaccgcc gggttcctgg cgatggcgct cgtgtcggtg
    11461 ctgacccggc cggacgtgcg ggaggcgctg accgcctccg gcgcgggcgg agtcgccggg
    11521 gcgatggacg aactgctgcg ggtgaacctg tcgatcggcg acgggctgcc gcggctggcc
    11581 ctggaggacg tgcggctcgg cgaggtcgac gtgcgagccg gtgaactggt cctggtgctg
    11641 gtggaggccg cgaaccacga tccggagcac ttcccggacc cgctggcctt ccggccggac
    11701 cgggagaacg ccgccgagca cctctccttc ggcggcgggc ggcactactg cccggcgacg
    11761 gcgctcggca agcggcacgc cgagatcgcc ctggagacgc tcctcgaccg gctgccgggg
    11821 ctgcggctcg cggtgccggt cgagcagttg gtgtggcgca ccaacttcat gaagcggctc
    11881 cccgagcggc tgccggtggc ctggtagccc ctcacgccca cgggtggcgc tgcccggcac
    11941 tcccggtgcc gggcagcgcc ctccggtgtc agcggccgta gcggatcagg gcgcggacca
    12001 tgcggcaggt ggtgtcggag ggcgggtgga tgccgatgtc ggcggccgtc gtgcgtatcg
    12061 tcgcgttcgt ggccttcgac gggacgtaga cgccggcgtc gaggagggcg atcgcgagac
    12121 gcatggcctt caggcggcgg ttgtgcgtca cgtaccactc gcgggggcgg cccgcgggaa
    12181 gcggcttccg ctggagcggc ttccagggtt cgagggacgg cgtccggatc acggccagag
    12241 ccatgggcta cctcctggcg aacgatgggg tgcgggccct ccccgggacc ctcaccttca
    12301 ccccctattt tagaggcccc cactgacaat cgcccctggc caggcagggt ttggggggtg
    12361 gtggagggcc gtctgggggg taccgtgtgg ggcatggaga tctggatcaa tcccgcctgt
    12421 tccaagtgcc gcagcgccct caccctgctc gacgcggagg gcgccgacta caccgtccgg
    12481 cgctacctgg aggacgtgcc ctcgcccgcg gagatcgggc aggtgctcga ccggctcggg
    12541 ctcgaaccgt gggacatcac gcggacgcag gaggccgtcg ccaaggagct cggggtgaag
    12601 gagtggcccc gggacgaggc caaccgggac cggtggatcg aggcgctcgc cgagcacccc
    12661 aagctgatcc agcggccgat catcacggcg gaggacggca cggccgtcgt ggcccggtcg
    12721 gaggaggccg tgcgggacgc cctgtcccgt tgagccgagt gaagccgagt gaagtcgagg
    12781 gaagccgagt gaaggggagc ctggaggacg tgcggtgagc gggacggtgg acgcggggcc
    12841 cggcgggctc ggcgtcgatc tgcatctgga gctcggtgcg agcggcagcc ggcgggccgt
    12901 gctcaccgag gccctgcgcg aggccgtccg cggcggacgc cttgcgcccg ggacgctgct
    12961 gccgccctac cggtcactcg ccgccgacct cgggatcgcc cggaacaccg tcgccgacgc
    13021 ctacgccgag ctggtcgccg agggctggct gacctcccgc cagggctccg ggacccgggt
    13081 cgccgagcgg gtcctcgccc ccgcccccgg accggcacgg cccgccgcgc cggcggcgct
    13141 cccgtacgac ctcgtccagg gcaagcccga ccccggcgcc ttcccgcgcg cggcctggct
    13201 ggcggccgcc cggcgggcgc tgaccgccgc gccccacgag gccttcggcg tcggggaccc
    13261 gcgcggccgg atcgaactgc gccgggccct cgccgcctac ctcgcgcggg tccggggcgt
    13321 acggaccacc ccggaccgga tcgtggtctg ctccggcacc gcgcacgccc tgcggctcct
    13381 cgcccgcgtc cccctggcga cgcacgcccg cgagaagccc gcccgccaga ccgccgcccg
    13441 caaggcgcct ccccggccct gggccgtcga ggcctacgga ctcccctacc accaggggct
    13501 gctgggcgag gcgggcatcc acacgctgcc gctggccgtc gacgaggacg gggcgcgcat
    13561 cgcggagatc cctccggagg cgggcaccgt cctgctcacc cccgcccatc agttccccac
    13621 cggcgggccg ctccaccccg agcgccgcgc cggcgtcctg gagtgggcgc ggcggtccgg
    13681 cgggctcgtc gtggaggacg actacgacgg cgagttccgc tacgaccggc ggccggtggg
    13741 cgccgtccag agcctcgacc ccgaccggac cgtcctcctc ggctccgtca gcaagagcct
    13801 ctcccccgca ctgcggatcg gctggatgtg cctgccggag gccctcgtgg acggggtcgt
    13861 cgaggcgaag ggcctgcgcg agccgcacac gtcggcgacg gagcagctca cgctcgcgga
    13921 gttcgtcgac tccggcgcct acgaccggca cgtccggcgg atgcgccagc accaccgtgt
    13981 gcggcgcgac cggctggcca cggtgctcgc ggagcgcgtg ccacgggtcc gggtgaccgg
    14041 tctctccgcc gggctgcacg ccctcgtgga actgcccccg ggcacggagc ggtcggccgt
    14101 cgccgccgcg gcccggcacg gggtcgccgt ggagggtctc gccgactacc ggcacccgga
    14161 ggcgctgggc ccggccctcc ccgacggtct cgtcgtcggc tacgccaccc cgccggaccg
    14221 gctgtacccg gccaccctgg acgcgctctg tcaggccttg gccgccgcgc tctgagcggc
    14281 gagccgctcc gcctccgtca ggatctcggt caggcgcagc ccgaagcggg cgtcgcacgg
    14341 gtgcggctcg ccggtgcgga ccgccgtgag cagggcgtcc acggcggtac cgaaggcttc
    14401 cagcgctcct ccccagcggg gcagttcggc ccggccggcg gcgccgtgca gggagagcgt
    14461 cacctccgcc gcctccggtg gggcgctcag cgtcagcgtg gccgtgctgc tcgcgcccga
    14521 gctgtggcgc aggaccaggt ggtgggtgtc ctccgggccc gccgccgccg tgatcgcggt
    14581 gacgtcgccg aggaccggca gatagaccga gaggacgtgc gggccgacgt cccacagccc
    14641 gcccttctcc cgccgccacg gcgagtccgc gtacacgctg gtggagcccg ccccgtagag
    14701 cgagcccagc cagtgcgcct cgcccaggaa ccagccgccg gccgccttcc gctcctcgat
    14761 ccagcgggcc gtctcctccg cgaagcgcag cgtgcagaag accaccgagg cgaccccggc
    14821 ctcctcggcg gcctcggcca cctcccgggc cgccgccacc gtcgtggcga ccggcttgtc
    14881 gagcaggacg tggcagccgg cccgcgccgc ccgcaccgcc aagggggcct ggacgtccgg
    14941 cgggagcgcg aaggccacgg cgtcactggc cgcgaagagg gcgtccacgt cctcgtacgc
    15001 gcgcgtgccg gacgcggcgg cgagctcctc cgccgcctcc gcgcgtctgc cccacacccc
    15061 gctgaactcg acgccggggt gcccggcgag cgcgggcgcg tgcgtgcggc cggcccaggg
    15121 gccggtaccg aggagtccga tgcggggctt cgcgcccaag tccttcgcca tgcccccagt
    15181 ctgccgggtg ccgctgacag cggatgcggc ccgggcccga aacccggtgg cgggcctccc
    15241 cccttccggt gttagcgtcg atccgccggc cgcgggactt cggtgcgact tccggaacct
    15301 gcctatgaag caacgtcttc gctgttcgta cccccattcc ccggccggcg cccatgagaa
    15361 ggggagagcc ttgtccgagc tcgtcgccgc cgaggacgtg ctcctcttcg tcaacgccgc
    15421 cgtgaccgcc accggccagc gcgaattccg ttcgtccgcc gccgcgcagc acttctcgct
    15481 gcgcttcgtc cacgagtacg tgcgggtcaa ctaccgcccc gtgtacgcgg ccgcgctcgc
    15541 cctcgacatc aaccaccaca acgccgccct gatcgtcgag cagctgctgc gcacgcccca
    15601 cgaggcgggc gggtccgagg cgaagcgggc cgaggggcgg ctgatcgccg cgcggctcgc
    15661 gctgctgccg ccgcagcgcg tctaccggct gttccgctcg ctgcgcgcag ccggggtcaa
    15721 caaccgccgc acgcgcgcga tcgtgcgcgc gtggctcgcc gcccggcccg atccggcgct
    15781 ggacgccgtg aagtaccggc ccgggctgaa ggccgccctc cggcacgtcc acggccggcc
    15841 cgccgacgag gagaccggcg acttcctctt cgcgcctggc cgccgggtcc gctacgggaa
    15901 cgccaccctc gacgcgtacc gccgcgccca ctacgagcag ggcgcgctgt acgagctgcc
    15961 gttcacggtc gccgagggct tcgccgcccg gcacaaggtg ccgcgcgcgg tgttcctgga
    16021 gcggatcgcg ccccggatga cgcggctcga acagctcagg acagcgcgcg ccgccgatct
    16081 gaccgtcatg ccgctcaccc gactcgccct gtacgtcctc tcgctcccgt tcgccgagcg
    16141 ggtggagcgg cgggccgagc tgacgcacgc gctgcgcgcc gccgcccggc gcgcggcggg
    16201 accgcacgcc ggaagctggg ggcgggtcgc cgcggtgctc gacgacagct tctcctcgtc
    16261 cggttcggcg gtgaagcggc gccgtccgct ggccgtcgcg ctgggctgcc acttcctcct
    16321 ggaggccctc gcggcgccgg gggcgtacac cccgctgtgg acctcgggcg gctccgaccc
    16381 gctgctcgtc cgtccgtacg gtccgacgcc gctgggcctg cggatcctgg acgccctgga
    16441 gaccggcccc gaccgggtcg tgatcgtctc ggacggctgg gacaacgcgc cgccggggct
    16501 cgcgggagag gtcctgcggg tgtggcgcac acggctcgac gccgagcgcc ggacgagcat
    16561 cgtccacctc aaccccgtat acgacgccga gggcttcgac gtgcgccggc tggcgccgag
    16621 cgtgccgacg gccgggatcc gggacgcgga ggatctggcg gccctggtgg agatcgcgca
    16681 gttcgcggag gggcggacgg ggttcgccga gctgggggcg tatctggacc ggcgtgtgga
    16741 gctgttcctg aaggaggccg ggggatgacg cggatcgatc tgaccgggct cgacgtccgg
    16801 ccggcgcagg tgtggggcgg ggtgcggatc gtgccgctgg tgcgggccga gccggtggcc
    16861 gggctgcggc tgcggcggga gctgtacgag ggctcgggcc tcgccaccgt ggacctcggc
    16921 gaccggacga cctacacgtc gtacgtcccg cacggcttcg tcgccgactg gacgggcccg
    16981 gggaccgggg cgggtgcgga gcagggcgtc gagtccgccg cctacgggac cctgctcggc
    17041 ggcgagggcg cgccgccgtg cgtgcccgtg cgccgtgtgc accggctggc caagcggcgg
    17101 cagggcgagc ggcggctgcg tttcctgccg ctccacctgg ccctcgacgg ctacctcgcg
    17161 ctgcacttcg gcggtccttc cgtggtctgg gacgactggt cccgcaaggc cctcgggcag
    17221 ggcctgtcgc cgcgggccga ggcggcgtac gcgggctggg cggtgccggg gctcggcgag
    17281 gcgctgcgga tcttcgagct ccacccgggc cagtgcgggc tgctcctgta cgtggcggac
    17341 gccctggccg cggccttcgt cgtcccgcat ccggacgact accgcgtgct gcacccgacg
    17401 ctcgtggagg acctgtacgg cgagctggtc caccagtacg cgtactacgg cgcgcaggtg
    17461 ccggagttca cggcgcggat ccgggacggc gtcggcggca tccgtaccct cgcggacctg
    17521 cgggcggcgg cgcgccagga ggagcgggcc tgggcggagg cgcacgacgg gctgatggcg
    17581 cgggacctgc tggagacctc gtacgccttc gagcgggtgt accggatggg ggacttcgac
    17641 ctgttccggt tcctgccgcc gttcctgcgg gacgggcggg agcagcacat cggcgagctg
    17701 atcaccgacc acaaggggcg ggcggcctat ctgaagacct tccggctctc cgagaagcag
    17761 atccggaagg ggcacctgct gcggctgctc gcggaccggg actggctcct ggaggcgacg
    17821 gcggaggccc tcggcaccac gtacgcggag gtcgtgcggc ggatcgaggc ggcagggctc
    17881 ggcgggctgc tcgacgcgca cgtcgtcgca cggcgcacac gggaaaaaga ggaaggctga
    17941 gtaacacggg gttcacaaac gggcaaccat cgggaaatcc cgtgttgcga agctgcgacc
    18001 ggacaccgaa caacacaccg cagctctcgc agcgccgcga gccgccgcgc acccgcagca
    18061 gcacgcccaa aggatgagac ccgtgacctt caaggctgag tacatctgga tcgacggcac
    18121 cgagccgacc gcgaagcttc gttccaagac gaagatcatc gtgagcggtg gcaccgcgct
    18181 cgacgagctg ccgatctggg gcttcgacgg ttccagcacg aaccaggcca agggccacgc
    18241 ctcggaccgc gtcctcaagc cggtcttcgt ctgcccggac ccgatccgcg gcggcgacga
    18301 catcctggtg ctgtgcgagg tcctcaacac ggacatgacg ccgcacgagt ccaacacgcg
    18361 tgccgcgctc gccgaggtcg ccgcgaagta cgccgcccag gagccgatct tcggcatcga
    18421 gcaggagtac accttcttcg acggcgagcg tccgctcggc ttcccggtcg gcggcttccc
    18481 ggccccgcag ggcggctact actgcggtgt cggcgccgac gagatcttcg gccgtgacat
    18541 cgtcgaggcg cacctggaga actgcctcac cgcgggtctg ggcatctccg gcatcaacgc
    18601 cgaggtcatg ccgggccagt gggagttcca ggtcggcccg ctggcgccgc tcacggtctc
    18661 ggaccagctg tggatcgccc gctggctgct gtaccgcacg gccgaggact tcaaggtctc
    18721 cgcgaccctg gacccgaagc cggtgaaggg cgactggaac ggcgcgggcg cgcacaccaa
    18781 cttctccacc aaggcgatgc gcgagggcta cgacgcgatc atcaccgccg ccgagtccct
    18841 cggcgagggc tcgaagccgc tcgaccacgt caagaactac ggcgccggca tcgacgaccg
    18901 cctgacgggt ctgcacgaga ccgctccgtg ggacaagtac tcctacggcg tctcggaccg
    18961 cggcgcctcg gtccgcatcc cgtggcaggt cgagcaggac cagaagggct acatcgagga
    19021 ccgtcgcccg aacgcgaacg tggacccgta cgtggtgacc cgcctgctgg tggacacctg
    19081 ctgcgaggcc ctggagaagg ccggccaggt ctgatccgag cccgtccgat ccccgtcccg
    19141 gatcgacgcg cgcgcaactt cgaagaggcg cccaccgtat tgaacggtgg gcgcctcttc
    19201 cgtcatcaag aaggccaggc aggaacgaat tccgaacatt cgctccactc atcacgcgat
    19261 ccgttgaggc gggcggatcc cccatccgtc cggcatcgca gccgatagcg tcagctccgt
    19321 gaagctggtg gtgcgggtga aactgctacc gacgcctgag gaggcggcgg cgctcgaagc
    19381 gaccctgcgc gcctgcaacg aggcggcgag ctgcgtctcc gtccgggcat tcgagagcgg
    19441 acgcacctcg cgggccgcac tccaagccct ggcgtatgcg gagctgaagg cacgggggct
    19501 gtcggcccag cccgcactgc atgtgctgcg aaaggtcgcc gacgcgtaca ccgcgctgag
    19561 ggcgagcctg aaggccggga gcctcggcag gcgtgtttcg aagcggtacc gcggggtggc
    19621 cggtaagccg gtcgtgttcc ggccggatgc ggcgcagccg ttcgacgacc ggtgcctgtc
    19681 gtggcagttg gataagcgca ccgtttcgat ctggacgacg tccgggcgaa tgaagggcct
    19741 cgccttcacc ggtcaagccg agcaactggc gatgctgact gcgtatcgca agggcgagac
    19801 cgatctgttg tgtcagggcg gggcgtggta cctggtcgct acttgcgagg tccccgaggc
    19861 tgccccgaat accgcccccg ccgggttcgt gggggtggat ctggggatcg tgaacatcgc
    19921 cacgacctca gccgggacgc gccacagcgg ccgccgcctc aaccggcgcc gggaggcgga
    19981 ccgcaggctg cgggcgaagt tgcagaagaa gggtacgaag tccgccatgc ggcgggcgaa
    20041 gcggcacgcg ggcaaggaag cgcgccgggc ccgggatatc aaccacaaga tcagtaagtg
    20101 catcgtggcg gaggctgaac gcaccggtcg cgggatcgcc ttggaggact tgggcggcat
    20161 tcgcgagcgg gtacggctca ggaagcccca acgcgtcacg ctgcactcct ggtccttccg
    20221 gcaactcggc acgttcatcg cctacaaggc gcaacgggcc ggagtgccgg tggtgtacat
    20281 cgaccccgcc tacaccagcc aggaatgctc ccggtgtcat cacgtcgacc gacgcaaccg
    20341 gccttcccag gccgtgttcg catgccaggc ctgcggcttc gttgagcacg cggacctgaa
    20401 ctcgtcccac aacatcgccg cccgcggctg gtggacgtgg gttcgcgggg ccgagtcgca
    20461 ggcccctgcc ctcacgctca ccgtgtagag ggctggacgc agccgggcac cgtcgaagcc
    20521 atcgacgaac cgagccgcaa acccggggac cgaattgatt cccgagtagt agactaggga
    20581 tatggccacg acgaagaacg agacagcgac aggtcgcgac gacctcgagc cgttctggcc
    20641 gtcccggcag cacgacgact tcgaccgggt ctgttgccgc gcgaggaacg cgtcggccct
    20701 ctaaagcccc gatc
//
