LOCUS       NZ_CP059991            23240 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces gardneri strain ATCC 15439 chromosome, complete genome.
ACCESSION   NZ_CP059991
VERSION     NZ_CP059991.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces gardneri
  ORGANISM  Streptomyces gardneri
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Genome-scale analysis on the transcription unit architecture of
            Streptomyces venezuelae ATCC 15439
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Biological Sciences, KAIST, 291 Daehak-ro,
            Yuseong-gu, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 6.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP013129
            Genome Coverage                   :: 187.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015710995.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 17:12:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,199
            CDSs (total)                      :: 8,101
            Genes (coding)                    :: 7,918
            CDSs (with protein)               :: 7,918
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 70 of 184
            Pseudo Genes (incomplete)         :: 147 of 184
            Pseudo Genes (internal stop)      :: 16 of 184
            Pseudo Genes (multiple problems)  :: 48 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:23:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1270188
            Orig. end                         :: 1293428
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059991.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23240
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="10"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..23240
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23240
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13240](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13240
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    181..196
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.43"
                     /tool="antismash"
     misc_feature    216..230
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            complement(2567..3409)
                     /db_xref="GeneID:95688046"
                     /locus_tag="H4W23_RS05720"
                     /old_locus_tag="H4W23_05715"
     CDS             complement(2567..3409)
                     /codon_start=1
                     /db_xref="GeneID:95688046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565367.1"
                     /locus_tag="H4W23_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05715"
                     /product="phosphoenolpyruvate hydrolase family protein"
                     /protein_id="WP_055644836.1"
                     /transl_table=11
                     /translation="MNTRSTVSRQDVLARLRAQVSAGRPIVGAGAGTGLSAKCAEAGGV
                     DLLIIYNSGRYRMAGRGSLAGLLPYGDANAIVQDMAREVLPVVRETPVLAGVCGTDPFR
                     RMDHFLDELKAMGFAGVQNFPTVGLYDGTFRVNLEETGMGYGLEVDMVRAAHERDLLTA
                     PYVFDPEQAADMAAAGADVLVPHVGLTTKGAIGAGTAMTLDQAAAAVQDMHDAARRVNP
                     DILVLCHGGPIAEPEDARYVLEHTTGVVGFFGASSIERLPTERAVTEQTRAFKSLALG"
     gene            complement(3501..4751)
                     /db_xref="GeneID:95688047"
                     /locus_tag="H4W23_RS05725"
                     /old_locus_tag="H4W23_05720"
     CDS             complement(3501..4751)
                     /codon_start=1
                     /db_xref="GeneID:95688047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948948.1"
                     /locus_tag="H4W23_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05720"
                     /product="Tm-1-like ATP-binding domain-containing protein"
                     /protein_id="WP_055646478.1"
                     /transl_table=11
                     /translation="MATVVLVGTLDTKGEEYAWLRERLREYGSDVLLVDTGVLPPPAHA
                     PVPDVTADVVARAAGHDLARLRTEADRGAAVAAMAQGLSRVVLDLYRKGKLHAVLAAAG
                     SGGSAIAAQAMRALPIGVPKVLVSTMAGGDVSPYVDSSDLTMMYSVVDISGLNTVSRQV
                     LGNAAAAAAGMARRHERNHDEQAGRGRPVVAATMFGVTTPAVDAARARLAELGYEVLVF
                     HATGAGGRAVEKLARDGVLDGVLDLTTTELADELVGGVLSAGPARLTAAGAMGIPQVVA
                     PGALDMVNFGPAATVPERFTGRRLLIHNATVTLMRTTTGEMAELGTTMGRKLRAARGPA
                     EVFWPLRGISAVDTTGGPFDDPEADRAGLDALRAAVRGGEVRVHELDAHVNDASFAVAM
                     ADRLHRLIADGTHGPGH"
     gene            4887..6332
                     /db_xref="GeneID:95688048"
                     /locus_tag="H4W23_RS05730"
                     /old_locus_tag="H4W23_05725"
     CDS             4887..6332
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (150-462). E-value: 4e-29.
                     Score: 93.8. Matches aSDomain:
                     nrpspksdomains_H4W23_RS05730_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GeneID:95688048"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.5"
                     /locus_tag="H4W23_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05725"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_063785796.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.3e-27, bitscore:
                     93.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIASTRLSRLLTGWSSEGPGPLPRRLADALRELAERGDVPAGS
                     VLPSQRELALVLGVSRSTVTSAYGLLEAEGRLESVRGSGSRLRASGALDRYVTEGRLIS
                     FDARAGTGTAGVADLSSGALPGLGAVGEAVGALTSGDLGGLLVADGYHPYGIPALREGI
                     AAYYRAAGVPTEAGQILVTAGSQQAVWLVAQALVEPGDTVVVEDPTYRGALEALRARGA
                     RLVPVGANGADGGEGSGAAAVRRLSAHGRPRLVYLQPTVHNPTGRTLDGAARREWQRVL
                     EDLELFTVEDTACAELALGEGAAGAPGPLVAGLPMASAVTVGTLSKLFWGGLRVGWVRS
                     SPQVVARLAKIKTSVDLSCSVVDQLVAVRLLDRLPEARARRRAELRAHRDTAEALLRSG
                     APHWEWTRPAGGAALWVRVPGTDTEALAQLARRRGVSVVPGSAFSPVDGFRDRLRLPYA
                     HGSAALEAALPTLLECARRAAAG"
     misc_feature    4923..4938
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.25"
                     /tool="antismash"
     aSDomain        5337..6272
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H4W23_RS05730_Aminotran_1_2.1"
                     /evalue="4.00E-29"
                     /label="H4W23_RS05730_Aminotran_1_2.1"
                     /locus_tag="H4W23_RS05730"
                     /protein_end="462"
                     /protein_start="150"
                     /score="93.8"
                     /tool="antismash"
                     /translation="YHPYGIPALREGIAAYYRAAGVPTEAGQILVTAGSQQAVWLVAQA
                     LVEPGDTVVVEDPTYRGALEALRARGARLVPVGANGADGGEGSGAAAVRRLSAHGRPRL
                     VYLQPTVHNPTGRTLDGAARREWQRVLEDLELFTVEDTACAELALGEGAAGAPGPLVAG
                     LPMASAVTVGTLSKLFWGGLRVGWVRSSPQVVARLAKIKTSVDLSCSVVDQLVAVRLLD
                     RLPEARARRRAELRAHRDTAEALLRSGAPHWEWTRPAGGAALWVRVPGTDTEALAQLAR
                     RRGVSVVPGSAFSPVDGFRDRLRLPYAHGSA"
     misc_feature    6449..6463
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 13.84"
                     /tool="antismash"
     misc_feature    complement(6450..6463)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.25"
                     /tool="antismash"
     gene            6748..8370
                     /db_xref="GeneID:95688049"
                     /locus_tag="H4W23_RS05735"
                     /old_locus_tag="H4W23_05730"
     CDS             6748..8370
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95688049"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="H4W23_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05730"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_055644834.1"
                     /transl_table=11
                     /translation="MDVCVVGAGPVGLTLAIGLRRLGVRVRIVDKAPATKREARALVLW
                     ARAREALDALGVGETLRHHGVELEAVTVHARDRALGELTTGWARSAHARPLNIEQHDIE
                     RLLSEELARLGTRVEWNTELTDVKVHDDRAEFTLRHENGTVESAVAPWIVGCEGTASVV
                     RDRLGIPFEGRRRTGLQVVQGNAHPTWRLGEAPGRGHIFLAPHRSLLVFPLPGGGFRFF
                     CFRDDPDPTLTAAPTIGELRDLVAETALMPGLRLEATEHLWLNRARFSDRVAARLRSGR
                     GLLAGDAAHAWAPVGGHGMNVGILGAHNLAWKLAAVHHGQAGESLLDTYSDEQRLLAVR
                     YIREMRFNFMELPLPPLGFRAFTATVPAALARRGFQRRLDLRLSDLSRSHRDSALSRHR
                     PGRRYRAGPRAGDRMPDVALTGGAGVQAAAAVRLHTLLGYERWTLVLHAARAGAGVLDD
                     LRQACDGFPAPVRVLPVTPWDTAEARRLGHPDDLRLVRPDGYVGLVAPLARPALLRSYL
                     VALAAEGRTPVRRAQEHPPHRPH"
     gene            8403..10004
                     /db_xref="GeneID:95688050"
                     /locus_tag="H4W23_RS05740"
                     /old_locus_tag="H4W23_05735"
     CDS             8403..10004
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /db_xref="GeneID:95688050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031966.1"
                     /locus_tag="H4W23_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05735"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_230882968.1"
                     /transl_table=11
                     /translation="MQTATVTQTTAVTQPATVPGATAPQTTAVTRPGHVPTLLPRARRR
                     TRANSTVSVVGAGMAGLVAAYELERLGFRVEVIEGSRRLGGRVHTHRFGASEGAPFVEL
                     GAMRIPTAHHRTMRYVEHLGLADQVRPFSTLLSEENAFLATSTGHVRLRDAPRALIADV
                     RASLPGAEHREETVVFGAWLAALVDAVAPPGLRDGLRADLARNLLDLVEEVDVSPHLLG
                     SAKDRMDVHGLFAAHPGIRAGCGTRLNSFLDDILTETSPELVRLACGMDQLVQRLAARV
                     RGPIWFGQRVSGFEVAADHVLVRIGGGPGATVRRCDYVLCTVPFSVLRGLTLTGFDEDK
                     LAVVRDVDYCPATKVAVHCREPFWEREGIRGGASFSGGRIRQTYYPPSAAEGATDPAQG
                     AALLASYTIGEDADHLGRMPPPLRHRTVVEELGRMHPQLLRRGMVRGVASLAWGEHPWT
                     EGGCTIRWGQDPAACEEQRRRAVRPQRRMFFAGEHCATEPAWIEGAVESALEAVDLIAR
                     HAPGRGVAPRVGLEAA"
     gene            10001..13240
                     /db_xref="GeneID:95688051"
                     /locus_tag="H4W23_RS05745"
                     /old_locus_tag="H4W23_05740"
     CDS             10001..13240
                     /codon_start=1
                     /db_xref="GeneID:95688051"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031967.1"
                     /locus_tag="H4W23_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05740"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_055644833.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1235.9,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFDLPRLYFGGTAVTRLPTGPRGGLVDLARNTALRGAAAASGS
                     ERPSAVGPFGEDGPAEAYHEHLAEHGARGGHFSGNGHLVLDARVTGVERADGAVETADP
                     VVGRAVDLWGHYNPYLGTTVNRARVFDVDPASAWTTTLMGGRFAFGREGRSHDAGYLCI
                     GDVAGFMPPRWHGFAPVCRTLHQFAIGAGEGLDWPAGAVDSPAVRTLRAAVEESEGGGI
                     VVQFTLERPAAPASPPASLKGVRAGGPEPGDAPGVWRLRGTIAPWRPDEPRTHPAGRLL
                     VPYGREVRAGGGPGPCTVRVSPDTVAFNWPFAPGLDAVGAVVRDGGPALELRTARSGLP
                     VAFLPAGAPEGGRVVTVPAASAEGVRRAADEGLALVRPATDGKDASTELLREREAVVLT
                     DEACLILEHPDPERGDEHAVEVPVRTFLRGVPAALDQIVVRQFPNPRALPLDPVASAPT
                     ARCGDIEIVRLRAGRAAGEKPGDAAPSPWCGVATDAHGRGWFTVSGARAGTARLLLAAG
                     PEELPPHDPRAPGSAEACYDHGDALDFWPWAGSAAVRVLPDDWQLDAVLQQDVTFELLH
                     REVFAYYEQLFPFMRDEVFSLTDRCKVETYAKLIWQMCDPANKDRTYYMPPTRDLSLPK
                     ARLLLKYLRAQSAAAAVPPAAVPSPVRSSPQITTRAQLRSALWQAVTVELATSLQYLYA
                     GYSVPTHGTGFEYVRSGVWTPRQLRLACGDGGESLTKGVRDSLFDVAREEMMHFLVVNN
                     ILMAMGEPFHVPEIDFGTPGRLPLPLDFALEPLHLGSLQRFIAIERPERLAGGTGALDG
                     PGPFGSPSELYAGIREGLTRVPDLFPVDRGRGGGEHHLFIGGTVNAVHPDYQLEVDDLS
                     SALFAVDFVTEQGEGGILDTEKAGSESHHETFVRLAELLMTERADGPHGEGAPWHPAYP
                     SLRNPTLDHGHPGRAAVSDPHARQVMRLFNRCYFMMLQLIVQHFGESPDASLRRSKLMN
                     AAIDVMTGMMRPLAEQLMPLESGWRGRTAGPSFELEEPPAYIARPDVARRGFAMRFRHL
                     AAMARECEGVPDRVPELMAWYAERFAPEGRS"
     gene            13245..14993
                     /db_xref="GeneID:95688052"
                     /locus_tag="H4W23_RS05750"
                     /old_locus_tag="H4W23_05745"
     CDS             13245..14993
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95688052"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942124.1"
                     /locus_tag="H4W23_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05745"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_079037717.1"
                     /transl_table=11
                     /translation="MSDSRSSSRGRSASGVGGRGAPGAAARSAVEETEVLIVGGGPVGL
                     ALALDLTHRGVDFVLAEAGDGRVTHPRVSTVGPRAMEAFRRWGVADAIRGAGWPADHTL
                     DIAWVTAVGGYELHRLRLGTAGERPLPSYTPEPEAICPQHWLAPLLTARLGVRPAGPVR
                     LGTRLVDLVRKPDRVGAVLVDGAGVRTTVHARYLVGCDGASSPVRKACGIAVPERHRTR
                     TLRNIVFRAPGLGAVLGPRAALVHFVTEPGGLRYPLRAMDGRDLYRLTCPAGPAGAERV
                     VRRAITPDVPVEILSDTTWHLTHRVASVYRDGRVFLAGDAAHTLSPSGGFGLATGVGDA
                     ADLGWKLAAELAGWAGAGLLDTYESERRPVAVSSLEESHRNLRRTVDRHLSPTLLDATE
                     DGERARAELGREIADSDPLREFDAPDLHFAHRYVSTAIAREEATADTGSEGADEADGPV
                     WNRTTLPGVRAPHAWLGPGRSTLDLYGGEFVLLCFDAGGGTRGGIGRGGGIGIGVGGGS
                     PDGLVRAFADRRVPLRVRRCRDPRVARRYERPYVLVRPDGHVAWRGAAPPPDPLRIADL
                     VRGAGG"
     gene            14990..16297
                     /db_xref="GeneID:95688053"
                     /locus_tag="H4W23_RS05755"
                     /old_locus_tag="H4W23_05750"
     CDS             14990..16297
                     /codon_start=1
                     /db_xref="GeneID:95688053"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031969.1"
                     /locus_tag="H4W23_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05750"
                     /product="cytochrome P450"
                     /protein_id="WP_079037716.1"
                     /sec_met_domain="p450 (E-value: 1.3e-15, bitscore: 56.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRTGGPGGTGTGAGRPAEAAHGPPEPFDPARLDLADPYPVYRR
                     YRETDPVHAVRDAVGGAASTTWYLFGHAEVAHVLAGRSFARSSPLTARSAPVPDGYVTL
                     RRVVENWLVFLDPPRHTRLRARVTPPLGAAAVAELRPRVREIAEELVAPLARRPAVELV
                     EGFAAPYPLLVIGGLLGVEAERWPWFRAQALALQQAGGTRGDRTPALLDEAERAAAELD
                     GYFHRELAARRTEDRGDLLSALALAGAEDPSLSGSELAATCTHLLTAGHETTTGLIGKA
                     VLALLARPEVADELRADPGLLPNAVDEFLRHDPPVQMVTRWAQRDTELAGRTVRRGDRL
                     QLVLGSAHRDPDRFPDPDVLDIHRDSGRHCAFGRGIHYCAGAALARAEAEIGLGVLLDR
                     LPALAPGARPGVEVEYAPDWVFHGPSRLTLTPASPP"
     misc_feature    complement(16342..16358)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: medium, score: 26.96"
                     /tool="antismash"
     misc_feature    complement(16343..16358)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: strong, score: 29.15"
                     /tool="antismash"
     gene            16373..16909
                     /db_xref="GeneID:95688054"
                     /locus_tag="H4W23_RS05760"
                     /old_locus_tag="H4W23_05755"
     CDS             16373..16909
                     /codon_start=1
                     /db_xref="GeneID:95688054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956470.1"
                     /locus_tag="H4W23_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05755"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_055644832.1"
                     /transl_table=11
                     /translation="MTTRRLTALTPEQAPGRAREVLTDIVERHGSVGEMVSTMAHSPAL
                     LDGYLSLSRAMKRVKIPRALSEKLSLAVQEWIGCGTCREAHRSAGRAAGLSETDIELAR
                     QGTSTDPREAALIGLALRVLAEPGSLSDDDVAEVRAHGWSDRVIAEVVGVVTLNLLTGA
                     FNLLAGIQPESGPEA"
     gene            complement(16863..17210)
                     /db_xref="GeneID:95688055"
                     /locus_tag="H4W23_RS05765"
                     /old_locus_tag="H4W23_05760"
     CDS             complement(16863..17210)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95688055"
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031970.1"
                     /locus_tag="H4W23_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05760"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_055644831.1"
                     /transl_table=11
                     /translation="MSAPLYQSKAEFFKTLGHPVRIRVLELLSEREHAVAEMLRDTGVE
                     AAYLSQQLAVLRRANLVVARREGVAVYYTLTGPRVTELLLVARSILSDDALAGRAVTPP
                     DRTPAGCPRGD"
     gene            complement(17332..17718)
                     /db_xref="GeneID:95688056"
                     /locus_tag="H4W23_RS05770"
                     /old_locus_tag="H4W23_05765"
     CDS             complement(17332..17718)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95688056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065375.1"
                     /locus_tag="H4W23_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05765"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_055644830.1"
                     /transl_table=11
                     /translation="MTIEWRYTVQQELGVLSLAGFLGADALGRFTGAVGWAVARGTGPV
                     VLDLSRLRGWSTGGQRAVSEAAHRLRAAGRSLELAAIPADGSLAATGDDPAIPVHCDLD
                     AAFAAHLDAGAEQRAWRSDAWPSE"
     gene            complement(17870..18487)
                     /db_xref="GeneID:95688057"
                     /locus_tag="H4W23_RS05775"
                     /old_locus_tag="H4W23_05770"
     CDS             complement(17870..18487)
                     /codon_start=1
                     /db_xref="GeneID:95688057"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020557615.1"
                     /locus_tag="H4W23_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05770"
                     /product="isochorismatase family protein"
                     /protein_id="WP_055644829.1"
                     /transl_table=11
                     /translation="MTQHTQPVDALIVVDVQTAFVVGDGAVPAADLIVERTTDLIARAR
                     RDGALVVHLQNDGPPGAEDEPHTPGWELHHPVLPGPRELVIRKPRDDGFHATPLGEVLD
                     GAGVQAVAVCGVMSEMCVQATARTALERGYRVVVPYDAHATQDCPAVPGICEAVPAATV
                     SRVAAYALGSDAEVTVPTADVTFTAPENAAPEAGRAEATARS"
     gene            19182..19412
                     /db_xref="GeneID:95688058"
                     /locus_tag="H4W23_RS05780"
                     /old_locus_tag="H4W23_05775"
     CDS             19182..19412
                     /codon_start=1
                     /db_xref="GeneID:95688058"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_05775"
                     /product="hypothetical protein"
                     /protein_id="WP_055644828.1"
                     /transl_table=11
                     /translation="MNDSTCGTSRTAPRRLSARDTAVVIVIIVTAALLAYTGWQIVSVV
                     VLTAEVATLGVRFLRRLRGGGGRPALGLTEV"
     misc_feature    19278..19280
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19419..20729
                     /db_xref="GeneID:95688059"
                     /locus_tag="H4W23_RS05785"
                     /old_locus_tag="H4W23_05780"
     CDS             19419..20729
                     /codon_start=1
                     /db_xref="GeneID:95688059"
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="H4W23_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05780"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_055644827.1"
                     /transl_table=11
                     /translation="MGRRENPIAQCSKSLRVLATWLRDGRAEVGLTYGQLAARTDFSAD
                     TLARAASGRHVPQSPSVVVAYAQACGRSTKEAERLWKLARRDEAHAQGVLRGHRSGGHI
                     SVVKDFADLRSAIVDLYQHDGGPPLRSLDQRIGGVGRLPHSTVGRVLAGRSTPGRALVL
                     AFAEACGVRRADLAEWGKAWDRADADRRTTRARRSRPTADLHTHDRVTPRDLQLLMSDL
                     EASARKEPGLKLLVTVPDPNEARPDQSARMTRELLVDQAQRRGELACPQCRRPSFGYDG
                     TRGWIAAPCRDCSVDRAVAAPGLAPDTPTLMLRLPAAPDRTPLPRRAPRTSWPRPSEGP
                     PTLSLRADDLPTLTDRPAPAEPAAPATNWFAPPRTAHTPPRPSTLPTPSGRAGTVRVRI
                     NIPGGRPVPPIGVDRPQHDESGPHRVNGGASPARPDA"
     gene            complement(20706..21662)
                     /db_xref="GeneID:95688060"
                     /locus_tag="H4W23_RS05790"
                     /old_locus_tag="H4W23_05785"
     CDS             complement(20706..21662)
                     /codon_start=1
                     /db_xref="GeneID:95688060"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_05785"
                     /product="hypothetical protein"
                     /protein_id="WP_152335275.1"
                     /transl_table=11
                     /translation="MGAQGTPSPQGAGAGVGAVGGRELSPAVVILSSVVGGISLTVGAL
                     LAVTSLAGYAAGAWVSPEPLSPGLLGAAMAGVAPALFAIGRARVWEEARCLVLPLAIVL
                     VGLFAVSLLNGGTLQAVHGGPLFLALFSLGWVATLGLLALAAVVCLAAQYRRPAPPGTA
                     GRPRVAPLPGWSKPLLAVLGSGWLGIGAGLLAFPAFWGPLLPWTVNRADAQGLGVWALA
                     LGVGVLGSLAEDDLARIRPALTAVPSVAVAVAVLLAVHARSVDWTSGPGVSLLSLVAGL
                     FTTGVAGRRLLSKAGAGSEGSPGPSRGAWSSRVRAGR"
     gene            complement(21662..22885)
                     /db_xref="GeneID:95688061"
                     /locus_tag="H4W23_RS05795"
                     /old_locus_tag="H4W23_05790"
     CDS             complement(21662..22885)
                     /codon_start=1
                     /db_xref="GeneID:95688061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573966.1"
                     /locus_tag="H4W23_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_05790"
                     /product="DUF2306 domain-containing protein"
                     /protein_id="WP_055644825.1"
                     /transl_table=11
                     /translation="MGRPTSTRRGRAAALAVTVVCLAYAPLAVTELWRYASPGAPAPGE
                     WLLARSVSPEFVAEAVRDRIGPYSRSLAPLIVHSVLGGLLMLLGPVQLLSAVRRRVRLH
                     RIAGTVFAVTVYVSMGGAALYLVRTPPEQAFSGAAFWIVLATILVGTVGSVTLGVLAAV
                     RGLPDLHQRWMLLCYGFLMTAPLLRLEWGFLPSLYPGLSIQDINRVAIMHLGSLVSFGA
                     LLASRALDRRATVPGLTGTWCPGPVLVAAHLAGAAGLTWITVAFLGQGTGGRRLLLAYV
                     VPYAVTYGVIAVRAARARVRGADWAREEWRLHLAALLLAPAFSAVAVPVLERTMGLDRL
                     TALTAGVGIGCGMLAYAAVTVVSLRVLYGRELLKRQRVSAERPTGQEAATATPGAVSAA
                     AVSGEGDR"
     misc_feature    complement(22959..22976)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.05"
                     /tool="antismash"
ORIGIN
        1 tccgtgaggg cccgccgggc cacgcgctcg gcctccggga ggtctccggc ggcgagggcc
       61 gccccggcga ggagttcgag atagcccggg cgcagggagg gctggagccg ggacaggtcc
      121 cggtcgccgc ccgcccgcag gagcgccccg cgcacccggt gcgggtcctt ggcgagcggg
      181 acgctgtggg cgagcatgca gcgggcctgc gtggcccacc agctctgggc ggtgcccacg
      241 gtggccgcgg cctcctccgc ggcggccagt ccctcggggg cgccgagtgg cagggcgtgg
      301 aggaggacgg tggcgcggat cgcccggctg aagccgagga gttcggtgcc gcccaggggg
      361 cgggcgacgg tgagggactc ctcggccagg tcgagcgcgg cagcgacgtt gcccgtgagg
      421 aagtggacgt acgccgagca gaggaggagc tgggagagcg cgaagggccg tccggcgcgg
      481 cgggcgatca cgatgccccg cgcggtgtgg cgctcggccg ctccgtactc ctccaggaag
      541 gcctcggtcc agcccaggcg caccagcgac tcgacgtggt cggcgagtcg gccgtcggtg
      601 aaggtgtcgg tgagggccgc ggcctccttc gcgcgggcgc gggcgacgac ggtctcgccc
      661 tcgtacgcct cgccgagcgc ggagagcgtg agggcctctg ccgtgccggc ctcgtcgcgg
      721 cggcggcgcg cctcgtcgag tgcccgggcg acctcctcgc ggacctcggg gtagcgggtg
      781 gcgaagaggg ccctggcgcc ccactcgacg acgagtccgg tccgcaggcc gtccctgggg
      841 cccgggctgc gctccagttc gcggcggagc agcgcgtccg cctcggggta gcggccgagg
      901 tgccgctcca tgaacgcgca gaggagaacg gcggaggtcc ggatcccggc cgtgtgctca
      961 ccttccgcac ggcgcgtggt gtcgtccggg ccgtcggggt cctcggggtc gtcggggtcg
     1021 tcggggtatc ccgtacgtcc ggggtccggg cggcaggtgt cgatgaggtg gtggaggacg
     1081 tcccggctct ccgcgacgcg tcccgccgcg ccgagggcct gggcccgccg gagcgtcagc
     1141 tcgtgtcgac ccgcgtggtg ttcgggggtg tcggggaggt ggtcgagggc ggcctggagc
     1201 cagtgggcgg cgcgggcggg gtccacggtc ccggtccgct cggcggcctc gacgagaacg
     1261 gccgccgtct cggcgtcggg gccggccgcg gcgccgacca ggtgcggggc tctggcggtc
     1321 gcgggcgcgc cggcccgggc gagcgcggcc gccgcccgcc ggtgcagctc gcggcggcgc
     1381 cacggatcga gcgcgccgcg gaccagttcc gggagggccg ggtggcgcgg gccgagcgta
     1441 cggccgtcct ggtcgggccg gacgaggtct cggccggcca gcgcgcgcag ggcggtgtcg
     1501 atcgcttcct gaccgtcgcc gggtgcactg cctcgccgat cggtggcgac ggccgtgacc
     1561 agttcggagg tgacacggcc gccgagcacg gctgccgcct cgacgaccgc ccgctccatc
     1621 gggccgagcg gtgtcagttc gtcgaggagg accgccaccg gtccggtgcc gggggcatcg
     1681 tcgcgccggt gacgggtgtg ggcgagggcc cggaagtaga gcgggttgcc gccgctggcc
     1741 gcgtagagct cctggaccgc ttcgggcggc accccggggg cgaggccccc ggcgcagtcc
     1801 tccggctcca gcgggccgag gtccagcccc gcgagggcgc cggagtcgac cgccctggcg
     1861 agggaggagg cgagggcggg cggggtctgt cgctcgcggc gggccgtgac gaccaggacg
     1921 ggagcgtgcg gcgggtgccg gaggagatgg tcgaggaggg cggcggtcgc cgggtccgcc
     1981 cggtggaggt cgtcgaggag gaggacgagc ccgggcgccg ggacacgccc cagcgcggcg
     2041 ccgatccgcc gtacgagtgc gccgtgtccc tgctgtgcct cccggtcgtt cgcctcttcg
     2101 acgagccggg ccagttcggc cagggccggg acggcggccc gtttcccgtg gtcgaggtcg
     2161 gcgcacgcgt ccaggacggc ctggaagggt gtgccgccct ccccttcggc ggttccggcc
     2221 cggccgctca ggacggtcgc tccgcggccc ctggcccgta cggcgaactc ggtcagcagc
     2281 cgggtcttgc cgatgccggg ctcgcccgtg acgtccacgg ccaccgggcc gacggcctct
     2341 gcgcggcagc ccagcagtcc gtccagccgg tccagttccc gggctcgccc gacgaggggc
     2401 gcgcggtcgg cgcacccccg gtccgcgaaa gtgtccacgt acagtcccct cgtgcggtca
     2461 cgccgtcgta cggtcgtgcc gccgtgcggt cgtgcttctt ccccgctctc agttgtacgg
     2521 cacgtcaccg acaggcccgt cggccggagg ccccgagcgg tggtcgtcag ccgagggcga
     2581 gggatttgaa ggcgcgggtc tgctccgtga cggcccgctc cgtgggcagc cgctcgatcg
     2641 acgaggcccc gaagaagccg acgacgccgg tggtgtgctc caggacgtac cgcgcgtcct
     2701 ccggctccgc gatggggccg ccgtggcaga ggacgaggat gtcggggttc acccgtctgg
     2761 ccgcgtcgtg catgtcctgg accgccgccg cggcctggtc gagcgtcatg gccgtgcccg
     2821 cgccgatggc gcccttggtg gtgagcccga cgtggggtac gaggacgtcg gcgcccgccg
     2881 ccgccatgtc ggcggcctgc tccgggtcga agacgtacgg ggcggtgagc agatcccgct
     2941 cgtgggcggc ccggaccatg tcgacctcca ggccgtaccc catgccggtc tcctccaggt
     3001 tgacgcggaa ggtgccgtcg tagaggccga ccgtggggaa gttctgcacg cccgcgaagc
     3061 ccatggcctt cagctcgtcc aggaagtggt ccatgcggcg gaacggatcg gtgccgcaga
     3121 cgccggcgag gacgggggtc tcgcggacca cgggcagcac ctcgcgggcc atgtcctgga
     3181 cgatcgcgtt ggcgtccccg tacggcagga gtccggcgag cgaaccccgg cccgccatcc
     3241 ggtagcggcc cgagttgtag atgatcagca ggtcgacccc gccggcctcg gcgcacttgg
     3301 cggagagtcc ggtgcccgcc ccggcgccga cgatcggccg gccggcggag acctgggcgc
     3361 gcagccgggc gaggacgtcc tggcggctga cggtggatcg ggtgttcacg gtcgtgactc
     3421 ctcgaagggt gggtgtccgg tcggcggctc cgtcaccggg ccggtcagtg gcccgttcgg
     3481 cggctccgtc aacgggccgg tcagtggccc ggtccgtggg tgccgtcggc gatgagccgg
     3541 tggaggcggt cggccatcgc gaccgcgaag gaggcgtcgt tgacgtgcgc gtcgagctcg
     3601 tggacgcgga cctcgccgcc ccggacggcc gcgcgcaggg cgtcgagacc ggcacggtcg
     3661 gcctcggggt cgtcgaaggg gccgccggtc gtgtccacgg cggagatgcc gcgcaggggc
     3721 cagaagacct cggcggggcc gcgtgcggcg cggagcttgc ggcccatcgt ggtgccgagc
     3781 tcggccatct cgccggtggt ggtgcgcatg agggtcaccg tcgcgttgtg gatgagcagc
     3841 cggcgcccgg tgaaccgttc cggcacggtc gcggccgggc cgaagttgac catgtcgagg
     3901 gcgccggggg cgacgacctg cgggatgccc atggcaccgg cggcggtgag ccgggcgggg
     3961 cccgcgctga gcacaccgcc gaccagctcg tcggcgagtt cggtcgtcgt caggtccagt
     4021 acgccgtcga ggacgccgtc cctcgcgagc ttctcgacgg cccggccgcc cgcgccggtg
     4081 gcgtggaaga cgaggacctc gtagcccagt tcggcgagcc gggcgcgggc cgcgtcgacg
     4141 gcgggggtgg tcacgccgaa catggtcgcc gcgacgaccg ggcgcccccg gcccgcctgc
     4201 tcgtcgtggt tccgctcgtg gcggcgggcc atcccggcgg cggccgccgc tgcgttgccg
     4261 aggacctggc gggagacggt gttgaggccg gagatgtcga cgacgctgta catcatggtg
     4321 aggtcgctgc tgtcgacgta cggggagacg tccccgccgg ccatggtgct gaccagcacc
     4381 ttcggtacgc cgatgggcag ggcccgcatc gcctgggcgg cgatcgcgga gccgccgctg
     4441 ccggccgcgg cgagcacggc gtgcagcttc cccttgcggt agaggtcgag gacgacgcgc
     4501 gagaggccct gcgccatcgc ggcgacggcg gcgccccggt ccgcctcggt ccgcagcctg
     4561 gccaggtcgt ggccggcggc gcgcgcgacg acgtcggcgg tgacgtcggg cacgggcgcg
     4621 tgcgcgggtg gcggaaggac gccggtgtcg acgaggagga cgtcgctgcc gtactccctg
     4681 agccgctccc gcagccaggc gtactcctcc cccttcgtgt ccagcgtccc gaccagcacg
     4741 acggtcgcca tgcccacacc cttctcccgg ccccgcgtca ggtaccgcgg tccggtcccg
     4801 tcctcgtcga tcctccgtcg cgcgacctgc gacgacaacg accactccgg gcgaattggc
     4861 ctgcgtcgtg gcgcactata agagccatga ccaggattgc ttcgacccgt ttgtcccgac
     4921 tcctcaccgg ctggtcctcg gaggggcccg ggcctctccc gcgccgactg gcggacgcgc
     4981 tgcgggagct ggccgagcgc ggcgacgtac cggcggggag cgtgctgccc tcgcagcgcg
     5041 aactggcgct ggtcctgggc gtcagccggt ccacggtcac ctccgcctac ggcctcctgg
     5101 aggcggaggg ccggctggag agcgtgcgcg gcagcggctc gcggctgcgg gcctcggggg
     5161 cgctcgaccg gtacgtcacc gagggccggc tcatcagctt cgacgcccgc gcgggcacag
     5221 ggacggcggg tgtcgcggac ctgtcgagcg gggcgctccc gggactcggc gcggtcggcg
     5281 aggccgtggg ggcgctgacc tccggcgacc tcggcgggct actggtggcc gacggctacc
     5341 acccgtacgg catcccggcg ttgcgggagg gcatcgccgc gtactaccgg gccgcgggcg
     5401 tgcccacgga ggccgggcag atcctggtga cggcgggctc gcagcaggcg gtgtggctgg
     5461 tggcgcaggc gctcgtggag ccgggcgaca cggtggtcgt ggaggacccg acctaccggg
     5521 gcgccctgga ggcgctgcgg gcgcggggcg cccggctggt gccggtcggg gcgaacggcg
     5581 cagacggggg cgaggggtcc ggcgcggcgg cggtgcggcg gctgagcgcc cacggcaggc
     5641 cccggctggt gtacctccag ccgaccgtgc acaacccgac aggccggacg ctggacggcg
     5701 ctgcacggcg ggagtggcag cgggtcctgg aggacctgga gctgttcacg gtcgaggaca
     5761 cggcctgcgc cgaactcgct ctcggggagg gggcagccgg tgctccgggg ccgctggtcg
     5821 cggggcttcc catggcgtcg gcggtgaccg tgggcacgct ctcgaagctc ttctggggcg
     5881 gtctgcgggt gggttgggtg cgctcctccc cccaggtggt ggcccggctc gcgaagatca
     5941 agacgtcggt cgacctgtcg tgctcggtcg tggaccagct cgtggccgtc cggctgctcg
     6001 accggctgcc cgaggcgcgg gcccggcgca gggccgagct gcgggcccac cgggacacgg
     6061 ccgaggcgct gctgcgctcc ggggctccgc actgggagtg gacccggccg gcgggcggtg
     6121 ccgccctctg ggtacgcgtg ccgggcaccg acaccgaggc cctcgcgcag ctggcgcggc
     6181 ggcgtggggt ctcggtcgtc ccggggtcgg ccttctctcc ggtggacggc ttccgggacc
     6241 ggctcaggct gccgtacgcc cacgggtcgg cggccctgga ggcggccctg cccactctcc
     6301 tggagtgcgc gcgtcgggcg gcggcgggct gacggacacc ggccggccga tgccggcggg
     6361 gagagttccc gtatcggctg tccagaactt gccacgcgcg tccaccgagg gagggcgggc
     6421 cacgcgattc gttcccgctc gccatggcgt ttctctgtca actccgtggc cgcggagcgg
     6481 agtccgaagg gcttgatccg gccagggagc cgtgactccg cgcgggctgc ccacggcgat
     6541 ggatcatcgc gggcggcttg attccaccca tcgtcactca aacggaccga atgatgcaca
     6601 ggtagtcacc ttccctgatg gcactgatcc cagcgcccct ctgcacgccc tgttgaaggt
     6661 gatcttccgc aagcattctg aacaccggga acggcgaacg gagagcgggg ggtggcccgg
     6721 ttgggcacag gcgaaggagc cggcgacgtg gacgtctgcg tggtcggggc gggcccggta
     6781 ggcctgaccc tggccatcgg cctgcgccgt ctcggggtcc gtgtccggat cgtcgacaag
     6841 gcgcccgcga ccaagcgcga ggcacgggcg ctggtgctgt gggcgcgggc cagggaggcg
     6901 ctcgacgccc tgggcgtcgg cgagacgctc cggcaccacg gggtggagct ggaggcggtg
     6961 accgtccacg cccgcgaccg ggccctcggc gaactcacca ccggctgggc acggtcggcc
     7021 cacgcccggc ccctcaacat cgagcagcac gacatcgagc gcctcctctc ggaggagctg
     7081 gcccggctcg gcacccgggt cgagtggaac acggagctga cggacgtcaa ggtccacgac
     7141 gaccgggccg agttcaccct gcggcacgag aacggcacgg tggagtccgc ggtcgccccg
     7201 tggatcgtcg gctgcgaggg caccgccagt gtggtcaggg accggctggg catccccttc
     7261 gaggggcgcc gccgcacggg cctccaggtc gtccagggca acgcccaccc gacctggcgg
     7321 ctgggcgagg cgccgggccg gggccacatc ttcctggctc cgcaccgctc cctgctcgtc
     7381 ttcccgctgc ccggcggagg tttccgcttc ttctgcttcc gcgacgaccc cgaccccacg
     7441 ctgaccgccg cccccaccat cggcgaactc cgtgacctgg tcgcggagac cgccctgatg
     7501 cccggtctgc gcctggaggc caccgagcat ctctggctca accgggcccg cttcagcgac
     7561 cgggtcgccg ctcggctccg ctcgggacgc gggctgctcg ccggggacgc ggcgcacgcg
     7621 tgggcgccgg tcggcggcca cggcatgaac gtcggcatcc tcggcgccca caacctcgcc
     7681 tggaagctgg ccgccgtgca ccacgggcag gcgggcgagt ctctcctcga cacctacagc
     7741 gacgagcaac ggctcctggc cgtgcggtac atccgcgaga tgcgcttcaa cttcatggag
     7801 ctgccgctcc cgccgctcgg cttccgggcg ttcacggcca ccgtgcccgc ggccctcgcc
     7861 cggcgcggct tccagcgccg cctggacctg cgactgagcg acctgagccg gagccaccgg
     7921 gacagcgcgc tgtcccggca ccggcccggc cgccggtacc gcgccggtcc gcgcgcgggc
     7981 gaccggatgc cggacgtcgc gctcaccggc ggtgccggcg tccaagccgc cgcggccgtc
     8041 cgcctgcaca ccctgctcgg gtacgagcgg tggacgctgg tcctgcacgc cgctcgggcc
     8101 ggcgcggggg tgctcgacga cctgcggcag gcctgcgacg gcttcccggc cccggtccgc
     8161 gtcctcccgg tgacgccctg ggacaccgcc gaggcccggc gcctcggcca ccccgacgac
     8221 ctgcggctcg tccggcccga cggatacgtc ggcctggtcg ctccgctggc ccgtcccgct
     8281 ctgctccgct cctacctcgt ggcgctcgcc gccgagggcc ggacacccgt ccggcgtgcc
     8341 caggagcacc cgccgcaccg tccgcattga tccgcagtga ttcgaggggg aatcggaccg
     8401 tcatgcagac cgcaaccgtc acgcagacca ccgccgtgac gcagcccgcc accgtgccgg
     8461 gagccaccgc accacagacc accgccgtca cccggcccgg ccatgtgccg acgctcctgc
     8521 cccgcgcccg ccgccgcacc cgcgccaaca gcacggtcag cgtcgtgggc gcgggaatgg
     8581 ccggtctggt cgccgcgtac gagctggagc ggctcgggtt ccgcgtcgag gtcatcgagg
     8641 gcagtcgccg gctgggcggc cgcgtccaca cgcaccggtt cggcgcgtcc gagggcgccc
     8701 cgttcgtgga gctcggcgcg atgcgcatcc cgaccgcgca ccaccgcacg atgcggtacg
     8761 tcgagcacct cggcctcgcc gaccaggtcc gccctttctc gaccctcctg tccgaggaga
     8821 acgccttcct ggcgaccagc accggtcacg tccggctgcg ggacgcgccc cgcgcgctga
     8881 tcgccgacgt ccgcgcctcg ctgccgggcg ccgaacaccg cgaggagacc gtggtgttcg
     8941 gcgcgtggct cgcggccctg gtcgacgcgg tggccccgcc ggggctgcgg gacgggctgc
     9001 gcgccgacct cgcccgcaac ctcctcgacc tcgtcgagga ggtcgacgtg tccccgcacc
     9061 tcctcggcag cgccaaggac cggatggacg tccacggcct gttcgccgcc catccgggga
     9121 tccgtgccgg ctgcggcacc cggctgaaca gcttcctcga cgacatcctc accgagacca
     9181 gtcccgaact ggtgcggctc gcctgcggca tggaccagct ggtgcagcgg ctcgccgccc
     9241 gtgtacgcgg tcccatctgg ttcgggcagc gggtgtccgg cttcgaggtg gccgccgacc
     9301 acgtcctcgt acggatcggg ggcgggccgg gagcgaccgt acggcgctgc gactacgtgc
     9361 tgtgcaccgt gccgttctcc gtgctgcggg gcctcacgct gaccggcttc gacgaggaca
     9421 agctcgcggt cgtgcgggac gtggactact gcccggcgac gaaggtcgcg gtgcactgcc
     9481 gggagccgtt ctgggagcgc gaggggatcc ggggcggcgc ctccttcagc gggggccgca
     9541 tccggcagac gtactatccg ccctcggccg ccgagggggc cacggatccg gcccagggcg
     9601 cggccctcct cgccagctac acgatcggcg aggacgccga ccacctcggc cggatgccgc
     9661 cgccgctgcg gcaccggacg gtcgtcgagg agctgggccg gatgcatccg cagctgctgc
     9721 ggcgcgggat ggtgcggggt gtcgcgagcc tcgcgtgggg cgagcatccg tggacggagg
     9781 gcggctgcac gatccgctgg gggcaggacc ccgccgcctg cgaggagcag cgccggcggg
     9841 ccgtgcggcc gcagcgccgg atgttcttcg ccggggagca ctgcgcgacc gagcccgcgt
     9901 ggatcgaggg ggccgtcgag tcggcccttg aggccgtgga cctcatcgcc cggcacgcgc
     9961 cgggccgggg cgtggcgccg cgggtcgggc tggaggcggc atgagcgtgt tcgacctgcc
    10021 ccggctgtac ttcggcggca ccgccgtgac ccggctgccc acggggccgc gcggcggact
    10081 cgtggacctg gcgcgcaaca ccgccctgcg gggtgcggcc gcggcgagcg ggtccgaacg
    10141 cccttcggcg gtgggcccgt tcggggagga cgggcccgcc gaggcctatc acgagcacct
    10201 ggcggagcac ggcgcgcgcg gcgggcactt ctccgggaac ggccatctcg tcctggacgc
    10261 gcgcgtgacc ggggtggagc gggcggacgg ggccgtcgag acggccgatc cggtcgtcgg
    10321 gcgggccgtc gacctgtggg gccactacaa cccgtatctg ggcacgacgg tgaaccgggc
    10381 ccgggtgttc gacgtcgatc ccgcctccgc gtggacgacg accctgatgg gcggccggtt
    10441 cgcgttcgga cgggaggggc gctcgcacga cgcgggctac ctgtgcatcg gggacgtggc
    10501 cggcttcatg ccgccccggt ggcacggctt cgcgccggtg tgccggacgc tccaccagtt
    10561 cgcgatcggc gccggagagg ggctcgactg gccggcgggg gcggtggact cccccgccgt
    10621 ccgcaccctg cgggccgccg tggaggagag cgaaggcggc gggatcgtgg tccagttcac
    10681 cctggagcga ccggccgcgc cggcctcgcc gcccgcgtcc ctcaagggcg tgcgtgcggg
    10741 cggtccggag cccggggacg cgccgggggt gtggcggctg cggggcacca tcgcgccctg
    10801 gcggcccgac gagccgcgca cacacccggc gggacggctg ctcgtcccgt acgggaggga
    10861 agtccgcgcc ggcgggggcc cggggccgtg caccgtgcgg gtctcccctg acacggtggc
    10921 gttcaactgg cccttcgcgc ccggcctcga cgccgtcggc gcggtggtac gggacggggg
    10981 acccgccctg gagctgcgga ccgcccgctc gggcctgccg gtcgccttcc tgccggccgg
    11041 agcgcccgag gggggccggg tcgtgaccgt gccggccgca tcggcggaag gggtacggcg
    11101 ggccgcggac gaagggctcg ccctggtgcg cccggcgacg gacggcaagg acgcgagcac
    11161 ggagctgctg cgggagcgcg aggccgtcgt cctgaccgac gaggcctgcc tgatcctgga
    11221 gcatcccgac ccggagcgcg gcgacgagca cgcggtcgag gtcccggtcc ggaccttcct
    11281 gcggggtgtt ccggccgcac tcgatcagat cgtcgtccgg cagttcccca acccccgcgc
    11341 cctcccgctg gatccggtgg cctcggcccc gacggcccgc tgcggggaca tcgagatcgt
    11401 ccggctccgg gccggccggg ccgccgggga gaagcccggt gatgccgcgc cgtccccctg
    11461 gtgcggtgtc gccacggacg cgcacgggcg cggctggttc accgtctccg gtgcgcgcgc
    11521 cggcacggca cggctcctgc tcgcggccgg tcccgaagag ctgccgccgc acgacccgcg
    11581 ggccccgggc tccgccgagg cctgctacga ccatggggac gccctcgact tctggccctg
    11641 ggcgggctcc gccgccgtcc gcgtcctgcc cgacgactgg cagctggacg ccgtcctcca
    11701 gcaggacgtg accttcgagc tgctgcaccg cgaggtgttc gcgtactacg agcagctgtt
    11761 cccgttcatg cgcgacgagg tgttcagcct gaccgaccgc tgcaaggtgg agacgtacgc
    11821 gaagctcatc tggcagatgt gcgatccggc gaacaaggac cggacgtact acatgccgcc
    11881 gacccgtgac ctgtccctgc ccaaagcgcg gctgctcctg aagtacctgc gggcgcagag
    11941 cgcggcggcg gccgtgcccc cggccgccgt cccgtcaccg gtccgctcct ctccgcagat
    12001 caccacccgg gcccagctgc ggtcggcgct ctggcaggcc gtcacggtgg agctcgcgac
    12061 ctcgctccag tacctgtacg cggggtactc ggtgcccacg cacggcaccg ggttcgagta
    12121 cgtccgcagc ggggtgtgga ccccgcggca gctgcggctg gcgtgtgggg acggcgggga
    12181 gagcctgacc aagggcgtcc gggacagcct cttcgacgtc gccagggagg agatgatgca
    12241 cttcctggtc gtcaacaaca tcctgatggc gatgggcgag ccgttccacg tccccgagat
    12301 cgacttcggc actcccggca ggctgccgct gccgctggac ttcgcgctcg aaccactgca
    12361 cctgggcagc ctccagcggt tcatcgccat cgagcggccc gagcggctcg cgggcggcac
    12421 cggcgcgctg gacgggccag gcccgttcgg ctcgccgagc gagctgtacg cgggcatccg
    12481 ggagggcctg acccgggtcc ccgacctgtt cccggtggac cggggacgcg gcgggggtga
    12541 gcaccacctc ttcatcggcg gcacggtcaa cgccgtacat ccggactacc agttggaggt
    12601 ggacgacctg tcgagcgcgc tcttcgccgt cgacttcgtg acggagcagg gcgagggcgg
    12661 gatcctcgac acggagaagg ccggctccga gtcccatcac gagacgttcg tgcgcctcgc
    12721 cgaactgctg atgacggagc gcgccgacgg gccgcacggc gaaggggcgc cgtggcaccc
    12781 ggcgtacccg tcgctgcgca atccgacgct cgaccacgga caccccgggc gggcggcggt
    12841 gagcgatccg cacgcgcggc aggtgatgcg gctcttcaac cgctgctact tcatgatgct
    12901 ccagctgatc gtgcagcact tcggggagag cccggacgcg agcctgcgcc gctcgaagct
    12961 gatgaacgcc gccatcgacg tgatgacggg gatgatgcgc ccgctggccg agcagctgat
    13021 gccgctggag tccgggtggc ggggacggac ggccgggccc tccttcgagt tggaggagcc
    13081 gcccgcgtac atcgcgcgcc ccgacgtggc ccggcgcggg ttcgcgatgc gcttccggca
    13141 tctcgcggcg atggcccggg agtgcgaggg cgtgccggac agggtgccgg agctgatggc
    13201 ctggtacgcg gagcgcttcg cgcccgaagg gaggagctga gaccgtgtcg gacagcagga
    13261 gcagcagcag gggcaggagc gcgagcggtg tcgggggcag gggcgcgccc ggggcggcgg
    13321 cccggtccgc ggtcgaggag accgaggtac tgatcgtggg cggcgggccg gtggggctcg
    13381 cgctcgccct cgacctcacc caccggggcg tggacttcgt cctggcggaa gcgggggacg
    13441 ggcgggtcac gcacccgagg gtctccaccg tcggcccgcg cgccatggag gcgttccggc
    13501 gctggggcgt cgcggacgcg atccggggcg cgggctggcc ggcggaccac accctcgaca
    13561 tcgcgtgggt gaccgccgtc ggcgggtacg agctgcaccg gctgcggctc ggcacggccg
    13621 gtgaacggcc cctgccctcg tacacgccgg aacccgaggc gatctgcccg cagcactggc
    13681 tggcccccct gctcaccgca cgcctggggg tacggccggc ggggcccgtc cggctcggca
    13741 cacgtctggt cgatctcgtc cggaagcccg accgggtcgg cgcggtcctc gtggacgggg
    13801 cgggggtgcg gacgacggtg cacgcccggt atctggtggg ctgcgacggg gcctcctccc
    13861 cggtccgcaa ggcctgcggg atcgccgtgc ccgagcggca ccgcacccgc accctgcgga
    13921 acatcgtctt ccgcgccccc gggctcggag ccgtgctcgg cccgcgcgcg gcgctcgtcc
    13981 acttcgtcac ggaaccgggc gggctgcgct atccgctccg ggcgatggac ggccgggatc
    14041 tgtaccggct gacgtgtccc gccggacccg ccggggcgga gcgcgtcgtg cggcgtgcga
    14101 tcacgccgga cgtgccggtg gagatccttt cggacaccac ctggcacctg actcatcggg
    14161 tggcgtcggt ctaccgcgac ggacgggtct tcctcgccgg ggacgcggcg cacacgctgt
    14221 cgccgtcggg cggcttcggg ctcgcgacgg gcgtgggcga cgcggccgat ctcgggtgga
    14281 agctggcggc ggagctggcg ggctgggccg gggccgggct gctcgacacg tacgagagcg
    14341 aacggcggcc ggtcgccgtc agcagcctgg aggagagcca ccgcaatctg cggcggaccg
    14401 tcgaccgaca cctctccccc acgctgctcg acgcgacgga ggacggggag cgggcccgcg
    14461 ccgaactggg ccgggagatc gcggactccg atccgctcag ggagttcgac gcacccgacc
    14521 tgcacttcgc gcaccggtac gtgtccacgg cgatcgcccg ggaggaggcc acggccgaca
    14581 ccgggtcgga gggggcggac gaggcggacg ggccggtctg gaaccggacg acactgcccg
    14641 gggtccgggc tccccacgcg tggctcggcc ccggccggtc gacgctcgac ctgtacggag
    14701 gggagttcgt cctgctctgc ttcgacgccg gaggcggcac ccgaggcggt atcggcagag
    14761 gtggcggcat cggcatcggc gtcggagggg gctctcccga cggtctcgtc cgcgccttcg
    14821 ccgaccgccg ggtgcccctc cgcgtacgac gctgccgcga ccctcgggtg gcgcggcggt
    14881 acgagcggcc gtatgtgctg gtgcgcccgg acgggcacgt ggcgtggcgc ggggccgccc
    14941 cgcctcccga tccgctgcgg atcgcggacc tggtgcgcgg ggccggcgga tgagcgggcg
    15001 gacgggcggg ccgggcggga cgggcacagg agcgggcagg ccggctgagg cggcacacgg
    15061 gccgccggaa cccttcgacc cggcgcggct cgacctggcc gacccctatc ccgtctaccg
    15121 gcgctaccgc gagacggacc cggtgcacgc cgtgcgggac gcggtcggcg gtgcggcgtc
    15181 cacgacctgg tacctcttcg gccacgcgga ggtggcgcac gtcctcgcgg gccggagctt
    15241 cgcccggtcc tccccgctga cggcgcgatc ggcgccggtc ccggacgggt acgtcacgct
    15301 gcggcgggtc gtcgagaact ggctcgtctt cctcgacccg ccccggcaca cgcggttgcg
    15361 cgcccgggtg acgccgccgc tcggggccgc cgccgtggcg gagctgcgtc cgcgcgtacg
    15421 ggagatcgcg gaggagctcg tcgcgccgct cgcgcggcgg ccggcggtgg agctcgtcga
    15481 gggcttcgcg gctccgtatc ccctgctggt catcggcggg ctgctcgggg tggaggccga
    15541 gcggtggccg tggttccgtg cgcaggcact ggccctccag caggcgggcg gcacccgggg
    15601 cgaccggacg ccggccttgc tggacgaggc cgagcgggcg gcggcggagc tggacgggta
    15661 cttccaccgg gagctggcgg cacggcgtac cgaggaccgg ggggacctcc tctcggcgct
    15721 ggccctggcc ggggcggagg atccgtcgtt gagcggctcg gagctggcgg cgacctgcac
    15781 gcatctgctg accgccgggc acgagacgac gacggggctg atcggcaagg cggtgctcgc
    15841 gctgctcgcg cgcccggagg tggcggacga actccgggcc gatccggggt tgttgccgaa
    15901 cgccgtggac gagttcctgc ggcacgaccc gcccgtgcag atggtgacgc gatgggctca
    15961 gcgggacacg gagctggcgg gccgtaccgt ccgccggggc gaccgcctgc agttggttct
    16021 tggctcggcc caccgcgacc ctgaccgttt cccggacccc gacgtcctcg acatccaccg
    16081 ggacagcggc cgccactgcg cgttcggtcg gggaatccac tactgcgcgg gggcggcgct
    16141 cgcgcgggcg gaggcggaga tcgggctcgg cgtcctgctc gaccggctgc ccgccctcgc
    16201 cccgggcgcc cggccggggg tcgaggtgga gtacgccccc gactgggtgt tccacggccc
    16261 gtcccgcctg acactgacgc cggcttcgcc tccctgacat cccgggaggc ctccgggaac
    16321 tcccgcaccc cagccctcgt tatacccccc acgggtataa cgaggaggtt ccgtgaccac
    16381 gagaagactg accgcgctca ccccggagca ggcgccgggc cgggcacgcg aggtgctcac
    16441 cgacatcgtc gaacggcacg gttcggtcgg cgagatggtg tcgacgatgg cgcactcgcc
    16501 cgcgctgctc gacggctatc tgagcctgtc ccgggcgatg aaacgggtga agatcccccg
    16561 cgccctcagc gagaagctgt cgctcgccgt gcaggagtgg atcggctgcg gcacctgccg
    16621 cgaggcgcac cgctccgccg ggcgcgcggc ggggctgagc gagacggaca tcgaactggc
    16681 ccgccagggc acgtcgaccg atccgcgcga ggcggcgctc atcggcctcg cgctccgggt
    16741 cctcgccgag ccgggctcgc tctccgacga cgacgtcgcc gaggtacggg cgcacggctg
    16801 gagcgaccgg gtgatcgcgg aggtggtcgg ggtggtcacg ctcaacctgc tgaccggggc
    16861 cttcaatctc ctcgcgggca tccagccgga gtccggtccg gaggcgtgac cgcccgcccc
    16921 gcgagggcgt cgtcggacag gatcgagcgg gccaccagga ggagttccgt gacccgtggg
    16981 ccggtcagcg tgtagtagac ggccacgccc tcgcgccggg cgacgacgag gttcgcccgg
    17041 cgcagcacgg ccaactgctg ggagaggtac gccgcttcga cgccggtgtc ccgcagcatc
    17101 tcggcgaccg cgtgctcacg ctcgctcagc agctccagga cgcggatccg gacggggtgt
    17161 cccagcgttt tgaagaactc cgccttcgac tggtagagcg gcgcgctcat cgcacccacc
    17221 ccacgcctcg cgtcgaacca gcaccgtgca ccatgccccc atactcgcgc cttccggggt
    17281 gcgcggacta gcgatctccg gagccggtcc gcgcggagag ccgggaccgt ctcactcgct
    17341 cggccacgcg tcgctgcgcc aggcgcgttg ttccgcaccc gcgtcgaggt gggcggcgaa
    17401 cgccgcgtcg aggtcgcagt ggaccgggat cgccgggtcg tcgcccgtgg cggcgaggga
    17461 gccgtcggcg gggatcgcgg cgagttcgag gctccggccc gcggcgcgga gccggtgggc
    17521 cgcctccgag acggcgcgct gcccgcccgt ggaccagccg cgcagccggc tcaggtcgag
    17581 gacgacgggt cccgtgccgc gcgcgaccgc ccagccgacg gccccggtga accggccgag
    17641 cgcgtcggca ccgaggaacc cggccaggga cagcacgccc agctcctgct ggaccgtgta
    17701 acgccattcg atcgtcatgc gcgtcgtctt ccctgtcgtt cggcggtggc gccgggtgcg
    17761 gcggcgggag ggcgtggggg ccggaccagg atggaacgat ttgcaggatt gtgcaattcc
    17821 catctcacgg agcggatggg ggtcacggac gggccgctcc ggtcgtgggt caggacctcg
    17881 cggtggcctc ggctcggccc gcctcggggg ccgcgttctc gggagccgtg aaggtgacgt
    17941 cggcggtggg gacggtgacc tccgcgtcgc tcccgagggc gtaggccgcg acgcgggaga
    18001 ccgtcgccgc cggtacggcc tcgcagatgc ccggcaccgc agggcagtcc tgggtggcgt
    18061 gggcgtcgta cggcacgacg acgcgatagc cgcgctccag ggccgtacgg gccgtcgcct
    18121 gtacgcacat ctcggacatc acgccgcaga cggcgaccgc ctggaccccg gccccgtcga
    18181 gcacctcgcc cagcggggtc gcgtggaagc cgtcgtcccg gggcttgcgg atcaccagct
    18241 cccgggggcc gggcaggacg gggtggtgga gttcccagcc cggcgtgtgg ggctcgtcct
    18301 ccgctccggg cggcccgtcg ttctggaggt ggacgacgag cgccccgtcc cttcgcgccc
    18361 gggcgatcag gtccgtcgtc cgctcgacga tcaggtcggc cgcgggcacg gccccgtcac
    18421 cgacgacgaa ggccgtctgc acgtccacga cgatcagggc gtccacgggc tgcgtgtgct
    18481 gggtcatccc gccatgatcg cgcccacgca ccccgctgct ccacaggatt tcggccgatc
    18541 gcgggcctga tgacgtctgt tcgtatcggg ggcacggcgt gggtcgcgtc cccgatggac
    18601 acggtcgccc gccgtgtgcg gcgtggtggg caggtcctgg cgccgggaac cggcgccagg
    18661 accttgagcg gacccgcggc aacgagtcgg ctctctccgg tgtctgagtt gcccgcagta
    18721 cctcgaagaa cgcccggcac gagcacaatc cgcagccggg cgcagggaca aagatcgggc
    18781 atgccgcaac ggacgtcaac agcgggacgt ggatgcggaa actttcggcg ctcatgccct
    18841 ctgacctggt cttctacagg tacggccgta cccggaagac cttcggaagc cagggacgct
    18901 cctgcggata ccggcgacgg gcccgcaaaa aggtgggacg catctgcgga tacccgcccc
    18961 tcatctctca cctgagcagc gagaacgtcc ggtcgaggca gtccccggag ggcgctcccc
    19021 tcagggacac ggacgcggat tcgaccggtc gggagttcgt ccggaggctc cgcatgctgc
    19081 aacatcactc accacgaggg cggcggcaac cgccctgaac gaccgatcag ttcacccgta
    19141 gtacgtcgcc cgcagtccac cggaaacaga ggttcctccc catgaacgac tccacgtgcg
    19201 gcacatcccg caccgcaccg cgccgcctgt ccgcccggga caccgcggtc gtgatcgtca
    19261 tcatcgtgac cgccgcctta ctggcgtaca ccggttggca gatcgtcagc gtggtcgtcc
    19321 tgaccgccga ggtggcgacg ctcggcgtgc gcttcctgcg ccgcctgcga ggcggcggtg
    19381 gccggcccgc gctggggctc acggaggtct agccaccgat ggggcgccgt gagaatccga
    19441 tcgcgcagtg cagcaaatcc ctgcgcgtcc tcgccacatg gctgcgtgat ggccgggcgg
    19501 aggtggggct gacctacggt cagctcgccg cccgcaccga cttcagcgcg gacactctcg
    19561 cgcgcgccgc ctcgggacgc catgtgccgc agagcccgag cgtcgtcgtc gcctacgctc
    19621 aggcctgcgg ccgcagcacc aaagaggcgg agcggctgtg gaagctggcc cgccgcgacg
    19681 aagcccacgc ccagggcgtc cttcgaggac accgcagtgg gggtcacatc agcgtcgtga
    19741 aggacttcgc cgacctgcgc tccgccatcg tcgacctcta ccagcacgac ggcggtcctc
    19801 ctctgcgcag cctggaccag cgcatcggcg gagtgggccg ccttccccac agcacggtcg
    19861 gacgtgttct ggccggccgg tcgacgcccg gccgcgccct cgtcctcgcc ttcgccgagg
    19921 cctgcggcgt acgcagggcc gacctcgcgg agtggggcaa ggcatgggac cgtgccgatg
    19981 ccgaccgccg caccacccgc gcgcgccgca gtcggccgac cgccgacctc cacacccacg
    20041 accgggtcac accgcgagac ctgcagctcc tgatgagcga cctggaagcc tccgcccgca
    20101 aggagcccgg cctcaaactc ctcgtgacgg tgcccgaccc gaacgaggcc cgccccgacc
    20161 agtccgcgcg catgacccgg gagctgctcg tcgaccaggc gcagcgacgg ggagagctcg
    20221 cctgcccgca gtgccgccgg ccgtcgttcg gctacgacgg tacgaggggg tggatcgcgg
    20281 ccccgtgccg ggactgctcc gtcgaccgtg ccgttgcagc cccgggcctg gcgccggaca
    20341 ccccgacgct gatgctgagg ctgcccgcgg cccccgaccg gaccccgctc ccacgacggg
    20401 caccccgcac gtcctggccg cgtccctcgg aagggccgcc cacgctgtcg ctgagggccg
    20461 atgacctccc gactctcacc gaccgcccgg cgcccgccga gcccgccgct ccggccacca
    20521 actggttcgc gccgccgcga accgctcaca cgccgccccg gccgagcacc ctccccacgc
    20581 cgtccggcag ggcgggtacc gtccgcgtcc gcatcaacat tcctggcggc aggcctgtcc
    20641 cgcccatcgg tgtggaccgt ccgcagcacg acgaatccgg tccacacaga gtgaacgggg
    20701 gtgcgtcacc ggcccgccct gacgcgtgaa gaccacgctc cacggctggg acctgggctc
    20761 ccttcgctgc cggcacccgc cttcgacagg agccggcggc ccgcgacacc ggtggtgaac
    20821 aggccggcca cgagggagag aagcgagacg cccgggccgg acgtccagtc gacggaccgg
    20881 gcatggacgg cgaggaggac ggcgacggcc actgccaccg acggcacggc cgtgagggcc
    20941 gggcggatac gggccaggtc gtcctcggcg agggagccga ggacgccgac gccgagcgcg
    21001 agcgcccaca ccccgaggcc ctgcgcgtcg gcacggttca ccgtccacgg caggagcggg
    21061 ccccagaagg cggggaaggc gaggagaccc gcgccgatgc cgagccatcc ggagccgagg
    21121 accgcgagga gcggcttcga ccagccgggc agcggggcga cgcgcggacg cccggccgtc
    21181 ccgggcgggg ccggcctgcg gtactgcgcg gcgaggcaca cgacggcggc tagcgcgagc
    21241 agcccgaggg tggcgaccca gccgaggctg aagagggcga ggaacagcgg gccgccgtgg
    21301 acggcctgga gggtgccgcc gttgagcaga ctcaccgcga agaggccgac gaggacgatc
    21361 gcgagcggca ggacgaggca gcgcgcctcc tcccagacgc gggccctgcc gatggcgaac
    21421 agcgcgggcg cgacccccgc catggcggcc cccaggagcc cggggctgag cggctccggg
    21481 gacacccagg cgccggccgc gtacccggcc aggctcgtga cggcgagcag ggcgcccacg
    21541 gtgaggctga tgccgcccac gacgctgctc aggatcacca cggcgggcga gagctcccgg
    21601 ccgccgaccg cgccgacacc ggcaccggca ccttgaggcg aaggtgtccc ctgcgcaccc
    21661 atcagcggtc gccttcccct gagacggccg cggcggacac cgcgccgggg gtggccgtcg
    21721 ccgcctcctg accggtcggc cgctcggccg acacccgctg ccgcttgagg agttcgcgac
    21781 cgtacagcac gcgcaggctc accacggtga cggccgcgta ggcgagcatc ccgcagccga
    21841 tgccgacgcc ggcggtcagg gccgtgagcc ggtcgaggcc catggtccgc tccagtacgg
    21901 gcacggccac cgccgagaac gcgggcgcca gaagcagcgc cgccagatgg aggcgccact
    21961 cctcgcgcgc ccagtcggca ccccgcacgc gcgcgcgtgc cgcccgcacc gcgatgacgc
    22021 cgtaggtgac ggcgtacggg acgacgtagg cgaggagcag tcgccgtccc cccgtcccct
    22081 ggccgaggaa ggccaccgtg atccaggtca gtccggcggc gcccgcgagg tgggcggcga
    22141 ccaggaccgg ccccgggcac caggtgccgg tcaggccggg gacggtggcg cggcggtcga
    22201 gcgcacggga cgcgagcagg gcgccgaagg agacgaggga accgaggtgc atgatcgcga
    22261 cacggttgat gtcctggatc gagagcccgg gatagagcga gggcaggaac ccccattcga
    22321 ggcggagcag cggagcggtc atcaggaagc cgtagcagag cagcatccag cgctggtgca
    22381 ggtccgggag gccgcggacg gcggcgagga cgccgagggt cacgctgccg accgtgccga
    22441 ccaggatcgt ggcgaggacg atccagaacg cggccccgct gaacgcctgc tccggcgggg
    22501 tgcggacgag gtagagggcg gcgccgccca tcgacacgta cacggtgacg gcgaagacgg
    22561 tcccggcgat ccggtgcagc cggacgcgcc gccgcacggc cgagagcagc tgtacggggc
    22621 cgagcagcat caacaggccg ccgaggacgg agtgcacgat cagcggggcc aggctgcggc
    22681 tgtacgggcc gatccggtcg cgcacggcct cggccacgaa ctccggcgag acggaacggg
    22741 cgagaagcca ctcgccgggg gcgggcgccc cggggctcgc gtaccgccag agttcggtga
    22801 ccgcgagcgg cgcgtacgcc aggcagacca ccgtgaccgc gagggcggcc gcccttcccc
    22861 gtctcgtgct tgtcggacgc cccacggcgg atccccctcc gaacgcgcga tagtcctttc
    22921 tggactatgg aggaaggtag ggcgggagac ggccggggtc aaccggtcgg taacaaagtc
    22981 ggagaggaag gcgagcgggt gaccggtcag ggctcgcggg tctccaccca ctgccagaag
    23041 tcgaccatca tccgctcgta ccggatgccg aactccagcg cctcgcgctg cccgcgcgtc
    23101 agcaactccc ccacgccctg ggccagttcc tcgtactcgc cgagggtccg ccggtgttcc
    23161 tcgacctgga ccggggcgtg gacgcgcggg ctggcgccga accacagctt gaggatgccg
    23221 cgctcacggg cctcgaccgg
//
