LOCUS       NZ_CP059991            21053 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces gardneri strain ATCC 15439 chromosome, complete genome.
ACCESSION   NZ_CP059991
VERSION     NZ_CP059991.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces gardneri
  ORGANISM  Streptomyces gardneri
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Genome-scale analysis on the transcription unit architecture of
            Streptomyces venezuelae ATCC 15439
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9054805)
  AUTHORS   Kim,W., Hwang,S. and Lee,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Biological Sciences, KAIST, 291 Daehak-ro,
            Yuseong-gu, Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 6.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP013129
            Genome Coverage                   :: 187.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015710995.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 17:12:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,199
            CDSs (total)                      :: 8,101
            Genes (coding)                    :: 7,918
            CDSs (with protein)               :: 7,918
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 70 of 184
            Pseudo Genes (incomplete)         :: 147 of 184
            Pseudo Genes (internal stop)      :: 16 of 184
            Pseudo Genes (multiple problems)  :: 48 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:23:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 356737
            Orig. end                         :: 377790
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059991.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            43..1797
                     /db_xref="GeneID:95687273"
                     /locus_tag="H4W23_RS01795"
                     /old_locus_tag="H4W23_01790"
     CDS             43..1797
                     /codon_start=1
                     /db_xref="GeneID:95687273"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603446.1"
                     /locus_tag="H4W23_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01790"
                     /product="MFS transporter"
                     /protein_id="WP_079037792.1"
                     /transl_table=11
                     /translation="MTPPPTLSKSRQQLILSVLMLCSVLIWLENTVLATALETLADPAR
                     GLGADPGQLQWATGSYTLAFATFMFTAGSLGDRFGHRTVFSSGLAIFAGSSLWAAYASD
                     AGQLIAARAAMGVGSALITPAMLAILMWTFTGPARAAAIGIFSTSAGVGMAAGPVLAGF
                     LLDRFWWGSVFLINVPVAALALVGLAVLVPNFRSPTLRPLDPAGMLLSISGLTALAYGL
                     IRAGQVAAWSRTDVWAPIVAGLVLLAVFVLVEMRVKAPSFDPRLLAQRSFGGGNVALGL
                     LLFGVAAITFYNAFYLQGALGLSPMKAGLANIPTAFGALAAAPLAARLVRRLSLRLVTV
                     PALTMAALTMGGYGFLGLHTPLVWIEILLLIQGLSIGMVIGPVTAALLSNLPLEQAGAG
                     SAVTNTVRQTGSVIGIAVGGTIMSIMYRRAIEPSLEGAPGPVQDQARVSAEQARHVATT
                     IHRPTLAQVADDAFIHAMRVGAGWIAVITLLGAAVLLITLPAAEKKKGPIPEPDYEEAG
                     SSVRERAEDLPWSWADVRLQTSAAPEPVGIACALQVSGELSSASSTGGVVDRAACEAGE
                     GRQECRTP"
     gene            1993..3381
                     /db_xref="GeneID:95687274"
                     /locus_tag="H4W23_RS01800"
                     /old_locus_tag="H4W23_01795"
     CDS             1993..3381
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687274"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018471371.1"
                     /locus_tag="H4W23_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01795"
                     /product="S41 family peptidase"
                     /protein_id="WP_055645473.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 1.4e-27, bitscore:
                     95.1, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIVTATAVALALVGAVAPAANATAHQPVTDGIWRTDGYGTVLSI
                     RNGNLQEYQTTAVSCIPGDTARRTGPGVYTTPKNILLTVRTRGDRDRASVRLDGDVGER
                     NLRRMTELPDACTHSAPGGPLASFDVFWQSFEENYPFFAAKGIDWHAVRDRYRPTVHEG
                     TTPDELFAVFSKMVEPLHDAHVAVCDVDADSDGYPDRLFAQARPGTVMPGGKLDAEVKK
                     FVVERDLKDARNIQDFGAGRITYADLPGGQGYLRISGFGGYAGDKATYAAELAELDKAL
                     DTVLDQERTRNLKGLVIDLRVNGGGSDAMGLNIAGRLTDTPYLAYSKRARNDPADPTRH
                     TRPQPLYVTPAPGPRYTGPVAVLTGGSTVSAGETFTQALMDRPGRTVRIGQSTQGVFSD
                     VMVRKLPNGMSVWLPNEELLTRSGRTFDGMGIPPHLTEPVFTTQEFDQNKDSAFDRAVK
                     VLQD"
     gene            3548..3778
                     /db_xref="GeneID:95687275"
                     /locus_tag="H4W23_RS01805"
                     /old_locus_tag="H4W23_01800"
     CDS             3548..3778
                     /codon_start=1
                     /db_xref="GeneID:95687275"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H4W23_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H4W23_01800"
                     /product="hypothetical protein"
                     /protein_id="WP_230882924.1"
                     /transl_table=11
                     /translation="METSAPFVGYDMAESGRVEVAPISGETPFADHLGETVLAVSEEGD
                     PDSGRLSLEISLGSGRVRCETWSGNLRLSSK"
     gene            3821..4590
                     /db_xref="GeneID:95687276"
                     /locus_tag="H4W23_RS01810"
                     /old_locus_tag="H4W23_01805"
                     /pseudo=""
     CDS             3821..4590
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969907.1"
                     /locus_tag="H4W23_RS01810"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01805"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAGVITASQPSWIVPFAGLSPRRFGTLVTQLRHEGADAVRRGRPW
                     SLPLEDRVLPVTAYWRTNLTLRQLAPLLGVSKSAVDRIVSHLGPLLALKPRSRFHKDTI
                     LIVDGTLAPTRDHSVAERSKNYRCSTNHQVVIDADTRRVVVVGRPMPGNRNDCKAWALS
                     GPKDAVGRTTVIANGGYRGTGLIIPHRRERGQSELPAGRKSTTLPTARSAPVSSTPSPV
                     "
     gene            complement(4673..5185)
                     /db_xref="GeneID:95687277"
                     /locus_tag="H4W23_RS01815"
                     /old_locus_tag="H4W23_01810"
     CDS             complement(4673..5185)
                     /codon_start=1
                     /db_xref="GeneID:95687277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450717.1"
                     /locus_tag="H4W23_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01810"
                     /product="hypothetical protein"
                     /protein_id="WP_055645472.1"
                     /transl_table=11
                     /translation="MSSSFQTIVDLDATAEDAVAHGERVAAWLVGEGIVGLPDYGPGPR
                     WEQATGFQEASGSDGLTVVTGRTVFFSPQHGGPPVCPFCAVAFGDGHREAFSPAMDEWW
                     DTGWAEVPCPACGRVVPLAAWEWAEDGLAFAYLGFEFRNGPALLPEFVAELGRVIGHRT
                     RFVQGRI"
     misc_feature    complement(5162..5176)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.96"
                     /tool="antismash"
     gene            <5463..5588
                     /db_xref="GeneID:95694941"
                     /locus_tag="H4W23_RS40730"
                     /pseudo=""
     CDS             <5463..5588
                     /codon_start=1
                     /db_xref="GeneID:95694941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735775.1"
                     /locus_tag="H4W23_RS40730"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TVQTRALHAYLR"
     gene            complement(5603..6085)
                     /db_xref="GeneID:95687278"
                     /locus_tag="H4W23_RS01820"
                     /old_locus_tag="H4W23_01815"
     CDS             complement(5603..6085)
                     /codon_start=1
                     /db_xref="GeneID:95687278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134580.1"
                     /locus_tag="H4W23_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01815"
                     /product="NADAR family protein"
                     /protein_id="WP_055645471.1"
                     /transl_table=11
                     /translation="MTIYFYGADEVPYGCFSNFSDHGFDLDGVWWPTSEHYFQAQKFKG
                     TRHADLFRRSRTPLRAAELGRDSSNPLRRDWERVKDDVMRRAVVTKFRAHADIRDILLS
                     TGEEEIVEDTTTDHYWGRGRTGNGKNMLGRMLVRTRHQLCAELTEALDGDGRRPRR"
     gene            6195..6785
                     /db_xref="GeneID:95687279"
                     /locus_tag="H4W23_RS01825"
                     /old_locus_tag="H4W23_01820"
     CDS             6195..6785
                     /codon_start=1
                     /db_xref="GeneID:95687279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018851849.1"
                     /locus_tag="H4W23_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01820"
                     /product="hypothetical protein"
                     /protein_id="WP_055645470.1"
                     /transl_table=11
                     /translation="MQLAYVYRVSKHDPADRDDHGHYTGAEDITSDHGKVEATYFQAVQ
                     AFASETHVGWDQYVYADSSRPCHEALARTRGLGLFPERVLVALPSEGLVEVVWQDKDGQ
                     IHSAVADEDEFPELADLIAGADVAALLPMYADERVPLFSVVMPDRDGVVRARWRAERSL
                     KSGRLHRPRVREVDEDAPWAPQPSVPFWKDFLG"
     gene            complement(6977..7660)
                     /db_xref="GeneID:95687280"
                     /locus_tag="H4W23_RS01830"
                     /old_locus_tag="H4W23_01825"
     CDS             complement(6977..7660)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687280"
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014906.5"
                     /locus_tag="H4W23_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01825"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055645469.1"
                     /transl_table=11
                     /translation="MSADKSAAATFRLLWETKESARSSLSVGGIVEAAIALADAEGLGA
                     VSMQRVAGELGYTAMALYRHVPGKDQLVALMADRAQGNPPAESGKEWRIEILNWADAAW
                     DFYLAHPWMLRVATTGAPTGPNELAWFEALLRPLAQSGLATENLVATAMFISSAVRDLA
                     RIATEIVPSGSDYGNLLAQVIQPDRFPTLASLMASGTVEDDGDVRPALDFGLNLILDGL
                     TTHTS"
     gene            complement(7663..8361)
                     /db_xref="GeneID:95687281"
                     /locus_tag="H4W23_RS01835"
                     /old_locus_tag="H4W23_01830"
     CDS             complement(7663..8361)
                     /codon_start=1
                     /db_xref="GeneID:95687281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983208.1"
                     /locus_tag="H4W23_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01830"
                     /product="hypothetical protein"
                     /protein_id="WP_055645468.1"
                     /transl_table=11
                     /translation="MAYTTSRLDGPPLRRFTGFTGVAFTVLQVIEVPLYFVHEGAPPDS
                     NVLTRIMLSLVVLVLLLGFVTGLRELVRQADPACGWVADLAYGAALAYIAVTFVAHSLQ
                     AGEAIAAEEPVDPTITAEGSYLLYGSIGRILTAVFLVAAGYAVVRSGLLSRWAARSAYA
                     IALINLAFVPSLYFGNDTGQFFSANGWGTTATIASLYAYWVLACGIALLRHRKARHYAG
                     QPGSASENRR"
     gene            8718..9917
                     /db_xref="GeneID:95687282"
                     /locus_tag="H4W23_RS01840"
                     /old_locus_tag="H4W23_01835"
     CDS             8718..9917
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687282"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031273.1"
                     /locus_tag="H4W23_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01835"
                     /product="S8 family peptidase"
                     /protein_id="WP_055645467.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.5e-39, bitscore:
                     133.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATHKRSHGLRNAAIATGTAAAAAAALFAGNLAGAAAPAEGTVHG
                     LGAPGAVSGSFVVILDASANKAELAKKYGGTLQRSYSSEVNGFSASGLSVDEAKRLAAD
                     PAVDTVVQNKRFSINETQEQPPSWGLDRIDQADTAGDQKYTYPDAGGEGVTAYVIDTGV
                     RISHQDFGGRASHGFDAVDNDQTADDGNGHGTHVAGTIAGTAHGVAKKAKVVAVRVLDD
                     NGSGTTDQVVAGIDWVTQNHSGPSVANMSLGGGADEALDAAVQRAIASGVTFAVAAGNE
                     SSDAGQGSPSRVPEALTVASSTKDDEQSDFSNFGSVVDLYAPGSDITSAWNDSDTGVKT
                     ISGTSMASPHVAGAAALYLAANPSATPADTATALTGAATADAIKNPSSGTANKLLKVAP
                     "
     gene            complement(10001..11053)
                     /db_xref="GeneID:95687283"
                     /locus_tag="H4W23_RS01845"
                     /old_locus_tag="H4W23_01840"
     CDS             complement(10001..11053)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687283"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058351.1"
                     /locus_tag="H4W23_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01840"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_055646577.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-60, bitscore:
                     202.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSRVHEASATALLERCRDRVRPALVEAVGRLHPWTGEMAAYAL
                     GWADATGKPDPGGSEGKGVRQTLAVLGAEAVGADSADAVPGAVAVELVHTFSLLHDDIM
                     DADGLRRQRPAVWRAYGTGPGVLAGDALLAQAVTILAEAPGRHTAAAVRHLCSTLNALV
                     SGQAEDLRFEDRPWRGPGAVEPEQYRSMAEQKTGALLGCALALGAILGGAADRTVTTLD
                     RAGRHLGLAFQAVDDILGIWGDPRVTGKPVHADLRQGKKTFPVLIALAGGGKAAHELAV
                     LLDSVERIDGETAEYAAELVEEAGGRTGTRREARRHLDAAHRTLREASLIHPAAQELDV
                     LFTHLLDRTW"
     gene            complement(11125..12273)
                     /db_xref="GeneID:95687284"
                     /locus_tag="H4W23_RS01850"
                     /old_locus_tag="H4W23_01845"
     CDS             complement(11125..12273)
                     /codon_start=1
                     /db_xref="GeneID:95687284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639312.1"
                     /locus_tag="H4W23_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01845"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_055645466.1"
                     /transl_table=11
                     /translation="MAGQVTERPATASAPEYQGALGSLSVNASLPEVLARGVRELRAAE
                     EAGDLREAARCGLAVAEACRRLGRIEEADRAWKASYRAARSAGHEGAMAWALWSGGTLA
                     RQRGALRLAYRLLGLAAEMGERGGDVVVRGYSLAGLAETGRIQGDYEAVGRLHEQLLAE
                     ARRRGEARHTVWALEGIAQMHRNTGAYDRALALFEEAAETASRAEDRRGWAWALRGIAD
                     VVSVRDGDVERALSLLSQAEEACREIRLASALAYNHKMRGNVLYRAGRYEQAREWYAQA
                     LEEFREMEEPRGTALSRLGLVKADARLGRDAADTAAELTGLRTTLDRIGLRHARDMVDK
                     AAAELGVGPLPDPTGDGTAAAAPVLPAVGAEALRKADVEGLR"
     misc_feature    12283..12303
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.75"
                     /tool="antismash"
     gene            complement(12586..13236)
                     /db_xref="GeneID:95687285"
                     /locus_tag="H4W23_RS01855"
                     /old_locus_tag="H4W23_01850"
     CDS             complement(12586..13236)
                     /codon_start=1
                     /db_xref="GeneID:95687285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478415.1"
                     /locus_tag="H4W23_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01850"
                     /product="DUF4360 domain-containing protein"
                     /protein_id="WP_055645465.1"
                     /transl_table=11
                     /translation="MRFPLLVSGAVAALFASALPAEAGPSSIVDPPPDRIVIDIATVNG
                     SGCPLGTAAIAVSEDNTAFTVTYSEYLAQVGGGSSPTAARRNCQLNLLVHVPQGFTYAI
                     ASADYRGYASLKSGASSTEKASYYFQGSPNTASRTHTFRGPYEDNWQATDDTDWAQLVW
                     APCGVQRNFNINTELRVNAGTSNPSATSYMTMDSTDGDISTIYHLAWKECPAD"
     misc_feature    complement(13356..13366)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    13541..13556
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.96"
                     /tool="antismash"
     gene            complement(13704..14435)
                     /db_xref="GeneID:95687286"
                     /locus_tag="H4W23_RS01860"
                     /old_locus_tag="H4W23_01855"
     CDS             complement(13704..14435)
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005307648.1"
                     /locus_tag="H4W23_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01855"
                     /product="carbonic anhydrase"
                     /protein_id="WP_055646576.1"
                     /transl_table=11
                     /translation="MSETPSAASSSSRRTLLRTALTGAALTAGSWAWDLPAASATSRVS
                     EKPRPATPAAALRELNAGNRRWRTRHQRHPHETLADRREMVSGQHPFAVVLACIDSRVA
                     PELVFDQGLGDLLTVRSAGEVLDEAVLGSVAYGVLELGIPLVVVLGHQSCGAVSAAVHA
                     EETGERLPAHIQYIADQIKPAIDHSHEGAARIDATVSAQVRRVRSQLAAEPDLAARIGA
                     GRLAIVGARYELTRQLVRPVD"
     misc_feature    complement(14265..14267)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    14526..14541
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            14695..15261
                     /db_xref="GeneID:95687287"
                     /locus_tag="H4W23_RS01865"
                     /old_locus_tag="H4W23_01860"
     CDS             14695..15261
                     /codon_start=1
                     /db_xref="GeneID:95687287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435029.1"
                     /locus_tag="H4W23_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01860"
                     /product="DUF4291 domain-containing protein"
                     /protein_id="WP_055645464.1"
                     /transl_table=11
                     /translation="MTPQYQIRADYDARTIVVYQAYSPAIADAALRAGRFVAPFSFHRM
                     TWIKPSFMWLMHRSNWARKPGQERVLAVRITREGWEEALSQAVLTTADPAAVAQAAVHV
                     QWDPERSARGAALNHYSIQVGIGRHLIRTFTDDWIVGLTDLTPQVRKAATLIQTGHASK
                     AQRLFPAERTYPMPLALEDVVSPGG"
     gene            15427..16266
                     /db_xref="GeneID:95687288"
                     /locus_tag="H4W23_RS01870"
                     /old_locus_tag="H4W23_01865"
     CDS             15427..16266
                     /codon_start=1
                     /db_xref="GeneID:95687288"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087517.1"
                     /locus_tag="H4W23_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01865"
                     /product="aldo/keto reductase"
                     /protein_id="WP_055645463.1"
                     /transl_table=11
                     /translation="MASTTFHIGGDLGVVRLGFGAMHLPTGPASDRQASLAVARRAVEL
                     GVTLIDTAHLYGGGANEELLAEALHPYPDELLITTKVGVARSASSGEWGLDGRPAVLRA
                     QVEQALRRLRVERIELLQLHRIDPETPLTDQLGTLRDLQAEGKIGRIGLSEVTVTELDQ
                     AREIINVASVQNRYNLLDREHEPVLTACEAAGIAFLPWRPVAAGASGAQAEIAAVAAEI
                     AATPTQVALAWLLGHSPVILPIPGTTRIDHLEENLAAADLHLTPAQRERLDRLPEQA"
     gene            complement(16281..>16481)
                     /db_xref="GeneID:95687289"
                     /locus_tag="H4W23_RS01875"
                     /old_locus_tag="H4W23_01870"
                     /pseudo=""
     CDS             complement(16281..>16481)
                     /codon_start=1
                     /db_xref="GeneID:95687289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558180.1"
                     /locus_tag="H4W23_RS01875"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="H4W23_01870"
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RAVAGQRGRGGRLPGFDRTR"
     gene            complement(16550..17212)
                     /db_xref="GeneID:95687290"
                     /locus_tag="H4W23_RS01880"
                     /old_locus_tag="H4W23_01875"
     CDS             complement(16550..17212)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687290"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018846478.1"
                     /locus_tag="H4W23_RS01880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01875"
                     /product="response regulator transcription factor"
                     /protein_id="WP_055645462.1"
                     /transl_table=11
                     /translation="MPIRVLVADDQAIIRTGLRIMLNAQPGIEVVGEAADGQEAVRLAR
                     ELRPDVCLFDIRMPVLDGLEATRLVAGPGVADPLAVVVITTFDLDEYVYGSLRAGARGF
                     LLKDTGPDLLAQAVRSASDGEALIAPSVTVRLLQAFADLPAGRPVAQPVAPVTAREEQV
                     LLAVARGLTNTEIADALHISLSTVKTHLASLMAKLGARNRVEIAMWAYETRRILPGT"
     gene            complement(17187..18359)
                     /db_xref="GeneID:95687291"
                     /locus_tag="H4W23_RS01885"
                     /old_locus_tag="H4W23_01880"
     CDS             complement(17187..18359)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687291"
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031367.1"
                     /locus_tag="H4W23_RS01885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01880"
                     /product="sensor histidine kinase"
                     /protein_id="WP_055645461.1"
                     /transl_table=11
                     /translation="MLRDDLRTLWTEPRPPDAPARVWRDWALLAASLGAVALEATLREN
                     VVWRPVAVVFAVWLCLLPLWRRTRPLAMVTLGFGSVILLQLASLVAAPREHVGLDTSMV
                     VLVLVYALPRWGSGREIVLGSAVILTAFVLGVVADDTPAAEQVGGFVFLSMPGLIGAAV
                     RFWGTARERQLEQVRSREREQLARELHDTVAHHVSAMVISAQAGRVLAGTDPSAAVEAL
                     EGVEEEGARTLEEMRAMVATLRNREAGAELAPPAGVADLERLVRTPGGRLRVDLGLDGE
                     LDTLPPAVDAAVYRIVQESVTNALRHAVDATEVVVRVAAERHTVRVSVRDNGRRTGRGR
                     EGYGLTGLRERATLLGGTLQAGPGADQGWHVEAELPRGRTESGAHPRPRR"
     gene            18535..20814
                     /db_xref="GeneID:95687292"
                     /locus_tag="H4W23_RS01890"
                     /old_locus_tag="H4W23_01885"
     CDS             18535..20814
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95687292"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018846480.1"
                     /locus_tag="H4W23_RS01890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H4W23_01885"
                     /product="MMPL family transporter"
                     /protein_id="WP_055646575.1"
                     /transl_table=11
                     /translation="MLSKALLRLGTSAARHPWRVIAAWLIAATLAVLAAIAIGGRTADS
                     MTAPGLDSQRAAQLIERAGTGQEGMTAQVVVTPLDGSATFFGHDSARTALTRLQTEVKR
                     LPHVLGTSDPAGALGAGGDTAVRGGLVSADGRIAVVRVQYPDQSRLSAEDLDALVDLGD
                     RLRAELPLRIEMGGNLFYAFSDPDGGASELIGLLAAATILFLAFGSLVAAALPIGMAVF
                     GLTVGVATMTVLAGVTDVPTFAPVLGSMVGLGVGIDYALFVLARHREYLAHGLDPREAA
                     GRAVATAGRPVVFAGGTVVVSILGLAVANVPFMTVGGIAVSIVVLIMVIASVTLLPAFL
                     GAAGPRLARAGRIGRALQTRKLGRLARRRNPAAGAAHTTGWRRWIGHVSRHPVPYAVGA
                     AGLLLTATLPLLGLRVGLPDDGSLPHSRTERRAYDLVAEGFGPGTNGPLVIAADPAGDP
                     GVLDRLVATVAADPGIASVAPTHIDRATGIATLVVFPTTSPQDKATADTIARLRTDVLP
                     TAIGHGPARAHVGGAAASLSDVGQRTSQRLPAFVAAVLAMSFLLLMLAFRSVLVPLKAV
                     LLNLLSIGASYGIMVAVFQWGWGGALIGLEATVPIVSFIPMFLFAILFGLSMDYEVFLL
                     SRVREEYLRTGDNRTAIVEGVSGTARIITSAALIMVAVFLSFAVAEDPSTKMFGLGLAT
                     AIFIDATVVRMVLVPATMTLLGRTNWWLPKWLDRMLPRGPVGTHDTDDTDAESTGEAPR
                     PRLADR"
     misc_feature    20907..20920
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
ORIGIN
        1 ccagtcgttc aggttcctgc cagtcaagac ccgaaggtgt ccatgacccc gcctccaacg
       61 ttgtcgaagt ccaggcagca gttgattctt tctgttctta tgctgtgttc ggttcttatt
      121 tggctagaaa ataccgtcct ggccactgcg ctggagaccc ttgcagaccc ggcccgcgga
      181 ctgggcgccg atcccggtca gctgcaatgg gcgactggtt cgtacactct ggccttcgcc
      241 acgttcatgt tcactgcagg ctcattgggc gatcgattcg gtcaccggac cgtgttttcc
      301 agtgggttgg cgattttcgc cgggtcctca ctgtgggcgg cgtacgcaag cgatgcggga
      361 cagctgattg cagctcgtgc tgcgatgggc gtgggcagcg cgctgatcac gcctgccatg
      421 ctggccatcc tcatgtggac cttcactggt cccgcgcggg ctgccgcgat cggaatattc
      481 tcgacgtcgg ccggtgtcgg aatggctgcc ggcccggtgc tggccggatt cctgctcgat
      541 cgtttctggt ggggctcggt ttttctcatc aatgtcccgg tcgcggcatt ggcgttggtc
      601 gggctcgccg tgctggttcc gaatttccgc agccccactc tgcgaccact ggaccccgct
      661 ggaatgttgc tgtcgatcag cgggctcacg gctctggcct acgggctgat ccgggcgggg
      721 caggtggctg catggagtcg taccgacgtc tgggcgccca tcgtcgccgg tctggttctg
      781 ctggccgttt tcgtactcgt cgaaatgcgc gtcaaggcgc ccagctttga tccacgactg
      841 ctcgcgcaac gctcattcgg tggcggcaac gtggcgctcg gattgctgct cttcggcgtg
      901 gccgccatta cgttctacaa cgcgttctac ctacaaggag cactcggact ttcgccgatg
      961 aaggcgggtt tggccaacat cccgaccgca ttcggcgcac tcgcggcggc gcccctcgcc
     1021 gcgcgcctgg ttcgccgcct gtcgctacgc cttgtcaccg tcccggcgct caccatggct
     1081 gcgctgacca tgggcgggta cgggttcctc ggactccaca ccccactggt ctggatcgag
     1141 atcctgttgt tgatacaggg gctctcgatc ggcatggtga tcggccccgt tacggccgcg
     1201 ttgctcagca acctgccgct ggaacaggcc ggcgcaggat cggccgtcac caacaccgtg
     1261 cgacagaccg gcagtgtgat cggaattgcg gtcggcggca cgatcatgtc gatcatgtac
     1321 cgccgtgcga tcgaaccttc actggagggc gcacccggtc cggtacagga tcaggcgcga
     1381 gtttccgccg agcaggcccg ccacgtcgcc accactatcc atcgacccac tcttgctcag
     1441 gttgctgacg atgcgttcat ccatgccatg cgcgtgggcg caggctggat cgcggtcatc
     1501 acactgctcg gagcagccgt gctgttgatt accttgcctg ctgccgaaaa gaagaagggt
     1561 ccgataccgg agccggacta cgaagaggcc ggcagctccg tcagagagcg tgctgaagat
     1621 ctgccgtggt cgtgggccga cgtgcgtctc cagaccagcg ctgcgcccga gccggtaggc
     1681 atcgcgtgcg cgctccaggt gagcggcgag ctctcgtcag cgtcgtcgac gggcggggtt
     1741 gtcgaccgtg cagcctgtga ggcaggcgag ggccggcagg aatgccgtac gccgtgacgg
     1801 tccaactccc cgtggtcgtc acgatcgcga ggccaccaag atgcccgtcc gccagatcgt
     1861 gtcgtcccgg gtacggcggg tagcgggggc tggccccacc cccgatcggc cggacagccg
     1921 gatggccagg tgaatcccgc gtcggcgacg gtggggcggt agcagcaagt cacctacaga
     1981 gaaggcaaga tcgtgcgcat cgtcacggcc accgccgtcg ccctggccct cgtcggcgca
     2041 gtcgcgccgg ccgccaacgc caccgcccac cagcccgtca ccgacggaat ctggcgcacc
     2101 gacggctacg gcaccgtgct gtccatccgg aacggaaacc tccaggagta ccagaccacc
     2161 gccgtcagct gcatccccgg cgacaccgcg cggcggaccg gccccggcgt ctacaccacg
     2221 cctaaaaaca tcctcctcac cgtgcgcacc cgtggggacc gcgaccgcgc ttccgtacgg
     2281 ctggacggcg acgtcggcga acggaacctg cgccggatga cggaactgcc cgacgcctgc
     2341 acgcattccg cccccggggg tccgctcgcc tccttcgacg tcttctggca gtccttcgag
     2401 gagaactacc ccttcttcgc cgccaagggc atcgactggc acgccgtacg cgaccggtac
     2461 cggcccacgg tccacgaagg gacgaccccg gacgaactct tcgccgtctt cagcaagatg
     2521 gtggagccgc tccacgacgc ccacgtcgcc gtctgcgacg tcgacgccga cagcgacggc
     2581 taccccgacc ggctcttcgc gcaggcccgc cccggcaccg tcatgcccgg cgggaagctc
     2641 gacgccgagg tcaagaagtt cgtcgtggag cgcgacctca aggacgcccg gaacatccag
     2701 gacttcggag ccgggcggat cacctacgcc gacctccccg gcgggcaggg ctacctgcgg
     2761 atctccggct tcggcggcta cgcgggcgac aaggccacct acgccgcaga gctggccgag
     2821 ctcgacaagg cgctggacac ggtcctcgac caggagcgca cccggaacct gaagggcctg
     2881 gtcatcgacc tgcgggtcaa cggcggcggc tccgacgcca tggggctcaa catcgccggg
     2941 cggctgaccg acacccccta cctcgcctac tccaagcggg cccgcaacga tcccgcggac
     3001 cccacccggc acacgcgccc ccagccgctg tacgtcacgc ccgccccggg cccccgctac
     3061 accgggccgg tcgccgtgct gaccggcggc tcgaccgtca gcgcgggaga gaccttcacc
     3121 caagccctca tggaccggcc cggccggacc gtacggatcg ggcagtccac gcagggtgtc
     3181 ttctcggacg tcatggtgcg caagctcccc aacggcatgt cggtctggct gccgaacgag
     3241 gagctgctga cccggtcggg caggaccttc gacggcatgg gcatcccgcc gcacctcacc
     3301 gagccggtct tcaccacgca ggagttcgac cagaacaagg actcggcgtt cgaccgggcc
     3361 gtgaaggtcc tgcaggacta atacttgtcc cgtataaggg cgtgagctgg ggctctgcct
     3421 gacggtacgg tcgttgggtg gagtcgatga gggtgaacga gtgcccgttg cacggggccg
     3481 gtgtgcgtcc tgattacctg atgcggtcgc cacgcacatc acgagcagtt cggactggtg
     3541 cctgatcgtg gagacgtcgg cccccttcgt gggatacgac atggcggagt caggtcgcgt
     3601 cgaggtggcg ccgatcagcg gcgagacacc gttcgcggat cacctcggcg agacggtact
     3661 ggcagtcagc gaagagggtg acccggacag cgggcggctc tcactggaga tctccctcgg
     3721 ctctggccgt gtccggtgtg agacctggtc cggaaatctc cgcctgtcca gcaagtgatc
     3781 agaacaccag ccacggcggg aaccgtgtga ggctcccgcc gtggctggtg tgatcacggc
     3841 gtcgcagccg tcctggatag tcccgttcgc cgggttgagc ccccgccgtt tcggcacgtt
     3901 ggtgacacag ctgcggcatg aaggagctga cgcggtccgc aggggccggc cgtggagcct
     3961 accgctggag gaccgggtgc taccggtcac ggcgtactgg cgcaccaact tgacgctgcg
     4021 gcagctcgca ccgctgctcg gcgtctcaaa gtccgcggtc gaccgcatcg tcagccacct
     4081 cggccccctg ctcgcgctca agccccgcag tcggttccac aaggacacca tcctcatcgt
     4141 ggacggaacc ctggccccca cccgcgacca cagtgtggcc gagcggtcga agaactaccg
     4201 ctgctccacc aaccaccagg tcgtcatcga cgcagatact cggcgcgtcg tcgtggtcgg
     4261 ccggccaatg cccggcaacc gcaacgactg taaggcgtgg gcactgtccg gacccaagga
     4321 cgccgtcggc cgcaccaccg tgatcgccaa cggcggctac cggggcaccg gcctgatcat
     4381 cccgcaccgc cgcgagcgcg ggcagagcga actgccggct ggaaggaaga gcacaacact
     4441 tcccaccgcc aggtccgcgc ccgtgtcgag cacgccttcg cccgtatgaa gacctggaag
     4501 atcctgcgcg actgccgctt gaagtgcgac ggcgtccatc acgcgatgag cggaatcgcc
     4561 cgcctgcaca accttgccct cggccgatag gcgagccgag cggacagcag ccgatcacgg
     4621 tcccactgac tcgaagatct ctacgggggc aagccctatt cggcgagggc gcctagatcc
     4681 ttccctgcac gaaccgcgtc cggtgcccga tcactcggcc cagctccgca acgaactccg
     4741 gcagcagcgc gggcccgttc cggaactcga accccaggta cgcgaaggcg agcccgtctt
     4801 cagcccactc ccatgcggcc agcggcacca cgcgtccgca cgccggacac ggcacctcgg
     4861 cccagccggt gtcccaccat tcgtccatgg ccggcgagaa cgcctcacgg tgcccatccc
     4921 cgaatgccac cgcgcagaac ggacagaccg gcggcccgcc atgctgcggc gagaagaaca
     4981 ccgtccgacc agtgacaacg gtcagcccat cgctcccgct cgcctcctgg aacccggtcg
     5041 cctgctccca ccgcggccca ggaccgtaat ccggcagccc cacgattccc tcgcccacca
     5101 gccacgccgc cacccgctcc ccgtgcgcga cggcgtcctc ggcggtcgcg tccaggtcaa
     5161 cgatcgtctg aaaagagcta ctcacagccg aacggtaggc ggcctactcg attccgcaaa
     5221 gcccgtacat cccgatccgt acgacaacgc tgccgcccgc gacaagagca ggaagtccgc
     5281 ttcccccgta ggcggcacgt cccacacatg atcgacaagg cccccccccc cgagccccag
     5341 agatcattta cgggacagcc cttaggacac caacgactgc acccggttcg ccaacgtaat
     5401 ggacgcgata cgagtacccg cctcggactg gcccggccgc tgacgcggcc ggccacgtca
     5461 gcaccgtcca aacccgggcc ctgcacgcct acctgcgctg acgcaacgcc aacgcccgcc
     5521 accccgacac actcgccgca caacgtcgag aacgtacccg aatccgcggt gagaagggca
     5581 tccgttgacc gcgtttcccg gatcaccgcc tcgggcgtcg gccatcaccg tcgagggctt
     5641 cggtgagttc ggcgcacaac tggtgacggg tgcgcaccag catccgcccg agcatgttct
     5701 tgccgttccc ggtcctgccc cgaccccagt agtgatcggt ggtggtgtct tcgacgatct
     5761 cttcctctcc ggtggacagg agaatgtcac ggatgtcggc atgcgcgcgg aacttggtca
     5821 ccaccgcacg gcgcatcacg tcgtccttga cccgctccca gtccctccgc agaggattgg
     5881 acgagtcacg gcccagctcg gctgcccgca gcggcgtgcg tgaacgtcgg aagagatccg
     5941 cgtggcgggt gcccttgaac ttctgcgcct ggaagtagtg ctccgaggtc ggccaccaga
     6001 ccccgtcgag gtcaaagccg tgatcggaga agttcgagaa gcatccgtaa gggacttcat
     6061 cggcgccata gaagtagatc gtcacgggaa cctcacgggt gttacggaga cccgcaccgt
     6121 gccaggcatg ccccagcccc tgcaaccagt tttcttcgcc gggcttcctc tgggcggccc
     6181 tggaagttga cgacgtgcag ctcgcctacg tctatcgcgt cagtaagcac gaccccgccg
     6241 accgtgacga tcacgggcac tacaccggcg cggaggacat caccagcgat cacggcaagg
     6301 tggaggcgac ctattttcag gcagttcagg ccttcgcctc agaaacgcac gtcgggtggg
     6361 accagtacgt ctacgccgac agcagccggc cctgccacga agccctggcc cgtacccgcg
     6421 ggctcggcct cttcccggaa cgcgtcctcg ttgccctccc ctccgaaggc ctcgtcgagg
     6481 tcgtctggca ggacaaggac ggccagatcc acagcgccgt cgctgacgag gacgagttcc
     6541 cggagctggc tgacctcatc gccggtgccg acgttgcagc gcttctgccc atgtacgccg
     6601 atgaacgcgt ccctctgttc tccgttgtca tgcctgacag ggacggagtg gtgcgggccc
     6661 gctggcgggc cgaacgatcc ctcaaatctg gccgactaca tcgaccgcga gttcgtgagg
     6721 tcgacgagga cgcgccctgg gctccgcagc cgtccgtgcc gttctggaag gacttcctcg
     6781 gctgagattg ctccccggct gatgccggcg tacatgatct ctgtcgtgca gggcgcccgt
     6841 acgtggccac cggagcagcc ggtccttcca gcggaagccc cccagccggc atcgccgatg
     6901 atcgtcgcgg tttgccggcc aaggtggcca tcgcggttct ctggtcgggg tcgcagaccg
     6961 gggtgacaag ccggcgtcag gaagtgtggg tcgtgaggcc gtcgaggatg agattgagac
     7021 cgaagtcgag ggcgggtctg acgtcgccgt cgtcttccac ggtgcctgag gccatcaggg
     7081 acgcgagggt ggggaaccgg tcgggctgga tgacctgggc gagaaggttc ccgtagtccg
     7141 agccggacgg gacgatctcg gtggcgatcc gggccaggtc gcggacggcg ctggagatga
     7201 acatggccgt ggcgaccagg ttctcggtgg cgaggccgga ctgggccaga ggtcgcagaa
     7261 gggcctcgaa ccaggccagc tcgttcgggc cggtcggggc cccggtggtc gctacgcgca
     7321 gcatccaggg gtgggcgagg tagaagtccc aggccgcatc ggcccagttc aggatctcga
     7381 tgcgccactc cttccccgac tccgccggtg ggttgccctg cgctcggtcg gccatcaggg
     7441 cgaccagctg gtccttcccg gggacgtgcc ggtacagggc catcgcggtg tagccgagtt
     7501 cgccggcgac ccgctgcatc gacaccgcgc ccaggccctc ggcgtcggcc agcgcgatgg
     7561 cggcctcgac gatgccgccg acgctgaggg aggaccgcgc gctctccttc gtctcccaca
     7621 ggagacggaa ggtggccgcc gcgctcttgt ccgctgacac ttctaccgcc gattctccga
     7681 ggccgatccc ggttgaccag catagtggcg ggctttgcgg tgtcggagca gcgcgatgcc
     7741 gcacgcgagg acccagtagg catagaggct ggcgatggtg gccgtggtgc cccagccgtt
     7801 ggcgctgaag aactgtccgg tgtcgttgcc gaagtacagc gacgggacga atgcgagatt
     7861 gatcagggcg atggcgtacg ccgaccgggc ggcccaccga gacagcagtc ctgagcgaac
     7921 cacggcatac ccggcggcca ccaggaacac cgcggtgagg atgcgaccga tcgagccgta
     7981 gagcaggtag gagccctcgg cggtgatggt cggatcgacc ggctcttcgg cggcgatagc
     8041 ctccccggcc tgcagggagt gtgcaacgaa ggtgaccgcg atgtaggcca gtgccgcgcc
     8101 gtaggcgagg tctgcgaccc agccgcaggc cgggtccgcc tggcggacga gctcgcgaag
     8161 ccccgtgacg aagcctagaa gcagtacgag gacgacaagg ctgagcatga tgcgggtcag
     8221 cacgttggag tcgggcggtg ccccctcatg gacgaagtag agcggcacct cgatgacttg
     8281 caggaccgtg aacgccacgc cggtgaaccc ggtgaagcgt cgcagcggtg ggccgtccag
     8341 acgcgatgtc gtatatgcca taagcgcgag tatatggcgt acacatagtc ggttcaatca
     8401 gaaccctgag gtcgccttca gatcacctcg gcatggacgc ccgccccagt ggcgccctga
     8461 ccctgtgcat gccggtcacc gtcgcccgct ccgaaccgtc gacgtgaacc gaggcccggg
     8521 cgccgctccg tgcccatttc ctgcaggagt tggccagatc gcgtgtgcga catggaggag
     8581 gtgcggagag atctttaaga aaccttgttg aataacgcct acccggggtt cgcacttgat
     8641 ttgctcctgc caacccgcac agggttctct cgaacgtttg acgccccaca cgtcaacacg
     8701 aggagagaac cagcttcatg gcaactcaca agcgatccca cggacttcgc aacgcggcga
     8761 tagccacagg taccgctgcc gcggcagccg ccgcgctgtt cgcgggcaac ctcgccgggg
     8821 cagccgcccc ggcggaaggc accgtgcacg gactcggtgc cccgggcgcc gtctccggca
     8881 gcttcgtcgt catcctcgac gcatccgcga acaaggcgga gctcgcgaag aagtacggcg
     8941 gcaccctcca gcgctcctac agctcggagg tcaacggctt ctcggcctcc ggtctgtccg
     9001 tcgacgaggc caagcgcctc gccgccgacc cggccgtcga cacggtcgtg cagaacaagc
     9061 gtttcagcat caacgagacc caggagcagc ctccgtcctg gggcctggac cggatcgacc
     9121 aggccgacac ggcgggcgac cagaagtaca cgtaccccga cgccggcggc gagggcgtaa
     9181 ccgcatacgt catcgacacc ggcgtccgga tctcgcacca ggacttcggc ggtcgagcca
     9241 gccacggctt cgacgccgtg gacaacgacc agaccgccga cgacggcaac ggccacggca
     9301 cccacgtcgc cggcaccatc gccggcacgg cccacggagt ggccaagaag gccaaggtcg
     9361 tggccgttcg cgtcctcgac gacaacggct ccggcacgac cgaccaggtc gtggcgggca
     9421 tcgactgggt gacccagaac cactccggcc cctccgtggc gaacatgagc ctcggcggcg
     9481 gcgccgacga ggctctggac gcggcggtcc agcgcgccat cgcctccggc gtgaccttcg
     9541 cggtggcggc cggcaacgag tcctccgatg ccggacaggg ttcgccctcc cgggtgcccg
     9601 aggcgctcac cgtggcgtcc agcaccaagg acgacgagca gtcggacttc tcgaacttcg
     9661 gctccgtggt ggacctgtac gcgcccggct cggacatcac ctcggcctgg aacgacagcg
     9721 acacaggcgt caagacgatc tccggaacgt cgatggccag cccccacgtg gcgggtgccg
     9781 cggccctgta cctggcggcc aacccgtcgg cgacgccggc cgatacggcc accgcgctga
     9841 ccggggcggc caccgccgac gccatcaaga acccgtcctc cggcaccgcc aacaagctcc
     9901 tgaaggtggc gccgtagcag caccgcacca ccggtcggcc gaccactgag tcacgcaggt
     9961 ggccctccac acaccagtgg agggccactt ccggttcctg tcaccaggtc cggtcgagca
    10021 agtgggtgaa cagcacgtcc agttcctgtg ctgcggggtg tatcagggac gcctcacgca
    10081 gggtgcggtg agctgcgtcc aggtgtcggc gagcttccct gcgggtcccg gtccggccgc
    10141 cggcctcctc cacgagctcc gcggcgtatt cggcggtctc gccgtcgatc cgctcgacgg
    10201 agtcgagcag caccgcgagt tcgtgcgcgg ccttgcctcc gccggccagt gcgatgagga
    10261 ccggaaaggt cttcttgccc tgtcggaggt cggcgtggac gggcttgccg gtcaccctcg
    10321 gatcgcccca gataccgagg atgtcatcca ccgcctgaaa tgcgaggccg agatggcgac
    10381 cggctcggtc gagcgtggtg acggtcctgt cggctgcgcc gccgaggatc gcgccgagcg
    10441 cgagcgcgca gcccagcagg gcacctgtct tctgttcggc catggaccgg tactgttccg
    10501 gctcgaccgc gccgggtccg cgccaagggc ggtcctcgaa gcgcagatcc tccgcctggc
    10561 cggacaccag cgcgttcagg gtgctgcaga ggtgccgaac cgcggcagcc gtgtggcggc
    10621 ccggggcctc ggcgaggatc gtcacagcct gggccaggag cgcgtcgccg gccaggacgc
    10681 ccgggccggt cccgtacgcc ctccagaccg ccgggcgctg ccggcgcagg ccgtcggcgt
    10741 ccatgatgtc gtcgtggagg agcgagaagg tgtggacgag ttcgacggcg accgcgccag
    10801 ggactgcgtc ggcgctgtcc gcgccgacgg cctcggcccc gagcacggcg agtgtctgcc
    10861 gcaccccctt gccctcggat ccgcccgggt ccggttttcc ggtcgcatcg gcccagccca
    10921 gcgcgtacgc cgccatctca ccggtccacg ggtgcaagcg gcccaccgcc tccaccagcg
    10981 cgggccggac ccggtcacgg caccgctcca ggagagcggt cgccgaggcc tcgtgcacac
    11041 gagaggtgct catcgcggtc acggccgtgg cgcctggcgc gacggtgaac gagcagaccg
    11101 ccggggcgga cgtcgggcga gcgctcaccg cagcccctcc acgtcggcct tccgcagggc
    11161 ttccgccccg accgccggca gtaccggtgc agcagccgcc gttccgtctc cggtggggtc
    11221 cggcagtggg cccaccccca gctcggccgc ggccttgtcc accatgtccc gggcgtgccg
    11281 cagcccgatg cggtccagcg tcgtgcggag tccggtcagt tcagcggcgg tgtccgcggc
    11341 gtcgcggccc aggcgggcgt cggccttgac cagtcccagc cgcgacagtg ccgtgccccg
    11401 cggctcctcc atctcgcgga actcctccag cgcctgcgcg taccactcac gggcctgctc
    11461 gtaacggccc gcccggtaca gcacgttgcc ccgcatcttg tggttgtagg cgagcgcact
    11521 ggccagtcgt atctcccggc acgcctcctc cgcctgcgag agcagggaca gggcccgctc
    11581 cacgtcgccg tcccgcacgg acaccacgtc ggcgatgcct cgcagggccc atgcccatcc
    11641 gcgtcggtcc tcggcgcgcg atgccgtctc ggccgcctcc tcgaagaggg ccagggcccg
    11701 gtcgtaggcg ccggtgttgc ggtgcatctg cgctatgcct tccagcgccc agaccgtgtg
    11761 ccgggcctca ccgcggcggc gggcctcggc cagcagctgt tcgtgcagcc tcccgaccgc
    11821 ctcgtaatcg ccctggatgc gcccggtctc ggcgagtccc gccagcgagt acccccgcac
    11881 gacgacgtcc ccgccccgct cccccatctc ggccgcgagc cccagcagcc ggtacgccag
    11941 cctgagcgca ccgcgctggc gggccagggt gccgccgctc cacagcgccc acgccatggc
    12001 cccttcgtga ccggccgaac gcgccgcccg gtagctcgcc ttccacgccc ggtcggcctc
    12061 ctcgatccgc ccgagcctgc ggcatgcctc ggccacggcc agcccgcagc gcgccgcctc
    12121 ccgcaggtcc ccggcctcct cggccgcccg gagttcccgg acgccccggg cgagcacctc
    12181 gggcagcgaa gcgttcaccg acaacgaccc cagcgcacct tggtactccg gcgccgatgc
    12241 cgtcgccggc ctctccgtca cctgacctgc catcagaacc tcctcgggtc ggctcgacga
    12301 tcaagccgac gcgaggatca agacggctgt ccgggaccca ggttcctcag cggtagcaat
    12361 gtccgtctcc gtacgggcac cgggtcattc tcaagtacta cgcggaggcc gggcctccac
    12421 agcgagacgt acaccggcgc agtccgtgcg agggagatct cctgacggcg acacgggcca
    12481 gggggctgtc ggtgaggcgg acagggcagc cggagtcgcc tccgtccgca cggcctatgc
    12541 cggtgggcgg ccgggcgcgt cggtgcgcca cggccgccgc gtgcgtcagt cggccgggca
    12601 ctccttccac gccaggtggt agatcgtgct gatgtcaccg tccgtggagt ccatggtcat
    12661 gtagctggtg gcgctcggat tcgacgtgcc ggcgttcacc cggagctcgg tattgatgtt
    12721 gaagttgcgc tgcacaccgc agggcgccca caccagttgg gcccagtcgg tgtcgtcggt
    12781 cgcctgccag ttgtcctcgt acgggccccg gaaggtgtgc gtgcgggagg cggtgttcgg
    12841 cgagccctgg aagtagtacg aggccttctc cgtgctgctc gctccggact tgagcgaggc
    12901 gtagccccgg tagtcggcgc tcgcgatcgc gtacgtgaat ccctgtggca cgtgcaccag
    12961 gaggttcagc tgacagttcc tgcgggccgc cgtgggtgag gaaccgccgc ccacctgcgc
    13021 gaggtactcg ctgtaggtga cggtgaaggc ggtgttgtcc tcggagacgg cgatggcggc
    13081 ggtgcccagg gggcagccgg agccgttcac cgtggcgatg tcgatgacga tcctgtccgg
    13141 cggcgggtcg acgatcgacg acgggccggc ttctgcgggc agtgccgagg cgaacagggc
    13201 ggcgaccgcc ccgctcacga gcaggggaaa tctcatgttt ctcccatccg gtgcttcggt
    13261 tcccgtggcg cggacgcacg ggtgcgtccg cgccacggac gtggatgcgg cgcgccatgc
    13321 tcaagtgcgg tggtcggcag ggacctaccg cggtggtgac atggcgcggg gaatcggaag
    13381 ggccggaagt acgcagtggg gtagtccaac tggcaatggt tgaactatca tgcgaatgaa
    13441 ctctgtccga ccaccccgcc ggtgcgagcg gggatggtcg aatgctaggg gcccgtgcac
    13501 gtcgaggcag ggtggcgccc agccattaac cgccttccgg atcacctctt tttggcgtgg
    13561 aagaggacat ggcgcctctt gaagccgata gcaatgccga cgatggcgat gggccagggc
    13621 tacagagagg cgacgggtca gggctacgga caccgggcgc cgaccggtgc gtacaccggc
    13681 cggcggtggg gtggagggcg cgatcagtcg accggacgaa cgagttgcct ggtcagttcg
    13741 tagcgcgcgc cgacgatcgc cagccgtccc gccccgatcc tcgcggcgag gtcgggctcc
    13801 gcagcgagct gcgaccgcac acgccgcacc tgcgccgaga cggtcgcgtc gatgcgggct
    13861 gcgccttcgt gcgagtggtc gatcgcgggc ttgatctggt cggcgatgta ctggatgtgc
    13921 gcgggaagcc gctctccggt ctcctccgcg tggacggctg cggacacggc gccgcacgac
    13981 tggtgcccga gcacgacgac gagcgggatg cccaactcca gcacgccgta cgccacgctg
    14041 cccagcaccg cctcgtccag gacctctccc gcggaacgca cggtgagcag atcgcccaga
    14101 ccttggtcga agacgagctc aggcgcgacg cgggagtcga tgcaggcgag tacgacggcg
    14161 aacggatgct gtcccgagac catttccctc ctgtcggcga gcgtctcgtg agggtgtcgc
    14221 tggtggcggg tgcgccagcg ccggttgccc gcgttcagct cacgtaaggc cgctgcgggg
    14281 gtggcggggc gcggcttctc gctcacgcga gacgtggccg acgccgcggg aaggtcccat
    14341 gcccaggatc cggcggtcag cgccgctccg gtgagggcgg tgcgcagcag tgtgcggcgc
    14401 gaggaggaag aggccgcgga aggggtctcg gatatgtgag attcagagga aggaggagtc
    14461 acacgaggaa cgtacgaccc cgtgaagccc acccggtttt gcattgctca acgcacagaa
    14521 cgtctttgac gactcttgga cagcggctcg gccgggcttc gctatgaggc gaggcgaccg
    14581 tcctcgtcgc agccatcagc gagtggcttc gagcagcgcg tccgaacctg ccccgggggc
    14641 ggtgaggcga aatcggctcg ccgcgccggt ggaccagatg gcagggtgcg gcgcatgacg
    14701 ccccagtatc agattcgtgc cgactacgac gctcgcacga tcgtggtcta tcaggcgtac
    14761 tcgcctgcca tcgctgacgc ggcgctgagg gcgggccgct tcgtcgcgcc gttctcgttc
    14821 caccggatga cgtggatcaa gccgtcgttc atgtggctga tgcaccgcag caactgggcc
    14881 cgcaaaccgg gacaggaacg tgttctcgcg gtacggatca cccgggaggg ctgggaggag
    14941 gccctgtcac aggccgtgct gacgaccgcc gacccggcag cggtggccca ggcagccgta
    15001 catgtccagt gggacccgga gcgttcggcg cgcggagcgg cgctgaacca ctacagcatc
    15061 caggtcggca tcggacgcca cctgatccgt acgttcaccg acgactggat cgtcggtctc
    15121 accgacctca ccccccaggt ccgcaaggcc gcgacactga tacaaaccgg gcacgcctcc
    15181 aaggcacagc ggctgtttcc tgcggagcgc acgtacccga tgcccctggc actggaagac
    15241 gtcgtttccc caggtggata acggcggact ggtgagggtg accatggctt ggtagtgccg
    15301 ggctcgtttg tcgtagcggg tggcgagggc ccggttctgc ttgaggtcga cctcgctggt
    15361 ggaccgatgc catagccaac tgcactgtta acgtggcccc ttgagcgagg ggaatgaaga
    15421 caacagatgg catcgaccac ttttcatatc ggcggggacc tgggggtagt gcggctcggg
    15481 ttcggagcca tgcacctgcc gaccgggccc gcctccgacc gccaggcgtc ccttgcggtc
    15541 gcccggcggg ctgtcgagct gggcgtcacg ctgatcgaca ccgcccacct gtacggcggg
    15601 ggcgccaacg aggaactcct cgccgaggcc ctgcacccgt acccggacga gcttctcatc
    15661 accaccaagg tcggcgttgc acgatcggcc tcctcaggcg agtggggact tgacgggcgg
    15721 ccggccgtcc tgcgcgctca ggtcgaacag gccctccgcc ggcttcgcgt tgagcgcatt
    15781 gagctgctcc agctgcaccg catcgatccg gagacacctc tcaccgatca gctcggcacg
    15841 ctgcgggacc ttcaggccga aggcaagatc ggccggatcg gactgtccga ggtcactgtc
    15901 accgagctgg accaggcacg agagatcatc aacgtcgcaa gcgtgcagaa ccgctacaac
    15961 ctgctcgacc gtgagcacga gcccgtgctc acggcctgcg aggcagcggg catcgcgttc
    16021 ctgccgtggc ggcccgtcgc ggcaggggcg tcgggcgcgc aggccgagat cgccgccgtg
    16081 gcggccgaga tcgccgccac gcccacgcag gtcgcgctcg cctggctcct cggccactcg
    16141 ccggtcatcc tcccgatccc gggcaccacc cggatcgacc acctggagga aaacctcgcc
    16201 gcggcagacc ttcatctcac tccggcccag cgcgagcgcc tcgacaggct gcccgaacag
    16261 gcgtaggtgc cccctcttcc tcacgagcgg agccagatga ggagggctgc ggcagtgacg
    16321 ctgccttggc agacgtatcc gcgcttgtca taacgggtgg ccacggctcc gaactgcttc
    16381 agctttccga tggcccgctc caccgtgttg cgccctttct accgggtccg gtcgaagccc
    16441 gggagccgtc caccacgtcc acgctgtccg gccaccgccc ggggcaggcg gaccttgtcc
    16501 gtgaccggat cgaactgggt gcagtccgcc cgccggcccg gtacccggct caggttccgg
    16561 ggaggatacg gcgcgtttcg taggcccaca tcgcgatctc gacccggttg cgggcgccga
    16621 gtttggccat caggctggcc agatgcgtct tcaccgtgct gaggctgatg tgcagtgcat
    16681 cggcgatctc ggtgttggtc agcccgcggg cgacggcgag gagcacctgc tcctcgcggg
    16741 cggtgacggg ggcgaccggc tgggccacgg gccggccggc gggcaggtcc gcgaatgcct
    16801 ggagcagacg gacggtgacg ctgggtgcga tgagcgcctc cccgtcggac gccgaccgta
    16861 cggcctgcgc cagaaggtcc ggtcctgtgt ccttgaggag gaatccgcgg gcgccggcac
    16921 gcagtgagcc gtagacgtac tcgtcgaggt cgaacgtggt gatgacgacc acggcgagcg
    16981 ggtcggcgac gcccgggccg gcgaccagcc gggtggcctc gagcccgtcg agtacgggca
    17041 tacgaatgtc gaacaggcag acgtcggggc gcagttcgcg ggccagacgt accgcttcct
    17101 gtccgtcggc tgcctcgccg accacctcga tgccgggctg ggcgttcagc atgatccgca
    17161 gcccggtgcg gatgatggcc tggtcgtcag cgacgaggac gcggatgggc accgctctcg
    17221 gtcctccctc tcggcagttc ggcttcgaca tgccagccct ggtcggcgcc ggggccggct
    17281 tgtagtgtgc cgccgagcag cgtcgcgcgc tcgcgcagtc cggtaagtcc gtatccctcg
    17341 cgaccccggc cggtgcgccg gccgttgtcc cgcacgctca cccgtaccgt gtgccgttcc
    17401 gcggcgaccc ggacgacgac ctcggtcgcg tcgaccgcat ggcgcagcgc attggtcacc
    17461 gactcctgca cgatccggta gacggcggcg tccacggccg gtggcagcgt gtccagttcg
    17521 ccgtcgagcc ccaggtcgac cctgaggcga ccacccgggg tgcgcaccag gcgctccaga
    17581 tccgcgacac cggcgggcgg cgccagctcg gcgccggcct cgcggttgcg cagcgtggcg
    17641 accatggcgc gcatctcctc cagcgtgcgc gccccttcct cctcgacccc ctccagcgcc
    17701 tcgacggcgg cggacgggtc ggtgcccgcg agcacccggc ccgcctgggc gctgatcacc
    17761 atggccgaga cgtggtgggc caccgtgtcg tgcagttccc gggcgagctg ctcacgctcg
    17821 cgggagcgta cctgctccaa ctgccgctca cgagcggtcc cccagaaccg cacggcggcc
    17881 ccgatcaagc cgggcatcga caggaagacg aagcccccga cctgttcggc ggccggggtg
    17941 tcgtccgcga cgacccccag cacgaaggcc gtgaggatca ccgcgctgcc cagcacgatc
    18001 tcccgtcccg atccccaccg gggcagcgcg tacaccagca cgagcacgac catgctggtg
    18061 tccaggccga cgtgctcgcg cggtgcggcg accagcgagg ccagctggag caggatcacc
    18121 gagccgaacc ccagcgtgac catcgccagt gggcgggtcc ggcgccacag gggcagcagg
    18181 cacagccaca cggcgaacac caccgccacc ggccgccata cgacgttctc gcgcagggtg
    18241 gcctccagcg ccacagcgcc caggctcgcg gcgagcagcg cccagtcccg ccacacccgg
    18301 gccggcgcgt cgggcggccg gggttcggtc cacagggttc gcaggtcgtc tcgcagcacg
    18361 gttctcagct taggtgccgc gccgtgccgc gcatcggccg aaagtacggg gtgtcactcg
    18421 gccccggggc cgagtgatcc gcggcccgcg ggccgatgcc gcggagcgcc gtggcgacga
    18481 acctcggcat cggaggccgt acaaggacgg ccgacgaggt ggttggagga cccgatgctc
    18541 tcgaaagccc tgttgcgcct gggcacaagc gccgcccgcc atccctggcg ggtgatcgcg
    18601 gcatggctga tcgccgccac gcttgcggtc ctcgccgcga tcgccatcgg cgggcggacc
    18661 gcggactcga tgaccgctcc gggactggac tcccaacgag ccgcgcaact gatcgagcgg
    18721 gccggcaccg gccaggaggg catgaccgcc caagtggtcg tcacccccct cgacggctct
    18781 gcgacgttct tcggccacga cagtgcgcgc accgctctca cgcggctgca gaccgaggtg
    18841 aagcggctgc cgcacgtgct cggcacgagc gacccggcgg gggcactcgg cgcgggcggg
    18901 gacaccgccg tgcgcggcgg cctcgtctcg gccgacgggc ggatcgcggt cgtccgggtg
    18961 cagtaccccg accagagccg gctgtcggcc gaagacctcg acgccctcgt cgatctcggc
    19021 gaccggctgc gcgccgagct gcccctgcgc atcgagatgg gcgggaacct cttctacgcc
    19081 ttctccgacc ccgacggcgg cgcgagcgag ctgatcggcc tcctcgccgc ggccacgatc
    19141 ctgttcctgg cgttcggctc gctcgtcgcc gccgcgctgc cgatcggcat ggcggtcttc
    19201 gggctgaccg tcggggttgc cacgatgacg gtactggcgg gggtgacgga cgtccccacc
    19261 ttcgcccctg tcctgggcag catggtcggg ctcggagtgg gcatcgacta cgcgctgttc
    19321 gtactcgcca ggcaccggga gtacctcgcg cacgggctcg atccccgcga ggcggcgggg
    19381 cgagcggtgg ccacggcggg gaggcccgtg gtcttcgccg gcggcaccgt cgtcgtatcg
    19441 atcctcggcc tggcggtcgc gaacgtaccg ttcatgacgg tgggcgggat cgccgtctcg
    19501 atcgtcgttc tgatcatggt gatcgcgtcg gtgacgctgc tgccggcctt cctcggcgcc
    19561 gccggcccac gcctggcccg ggccggccgg atcggccggg ctctgcagac cagaaagctg
    19621 ggccgactcg cacggcggcg gaacccggcg gcaggcgccg cccacaccac cgggtggcgt
    19681 cgctggatcg ggcacgtcag ccggcacccg gtgccgtacg ccgtcggcgc ggcggggctg
    19741 ctgctgaccg cgacgctgcc cctgctcggc ctgcgcgtcg gcctgcccga cgacggctca
    19801 ctgccccaca gccgtaccga gcgccgggcc tacgacctcg tcgccgaggg gttcggcccg
    19861 ggcaccaacg gtcccctcgt catcgccgcg gaccccgccg gtgatccggg agtgctggac
    19921 cgtctcgtcg cgacggtcgc ggcggatccg gggatcgcct ccgtcgcgcc gacgcacatc
    19981 gatcgggcca ccggcatcgc gaccctcgtg gtgttcccga ccaccagccc tcaggacaag
    20041 gccacggccg acaccatcgc ccggctgcgt accgacgtgc tgcccacggc gatcgggcac
    20101 ggcccggcca gggcccacgt cggcggcgcc gccgcgagcc tgtccgatgt gggccaacgc
    20161 accagccaac gcctgccggc gttcgtcgcc gccgtgctgg cgatgtcgtt cctgctgctg
    20221 atgctggcct tccgctcggt actcgtaccg ctcaaggcgg tactgctgaa cctgctgagc
    20281 atcggcgcgt cctacggcat catggtcgcg gtcttccagt ggggctgggg aggcgcactc
    20341 atcgggctgg aagcgacggt tccgatcgtg tcgttcatcc cgatgttcct cttcgccatc
    20401 ctgttcggcc tgtcgatgga ctacgaggtg ttcctcctct cccgcgtacg cgaggagtac
    20461 ctgcgcaccg gggacaaccg cacggcgatc gtcgagggcg tctcgggcac cgcccggatc
    20521 atcacctcgg ccgccctcat catggtggcg gtcttcctgt ccttcgccgt cgccgaggac
    20581 ccctccacca aaatgttcgg gctcggcctg gccaccgcga tcttcatcga cgccacggtc
    20641 gtccgcatgg tgctggtacc ggcgaccatg acactcctcg gccggaccaa ctggtggctg
    20701 ccgaagtggc tggaccggat gcttccccgc ggcccggtcg gcacccacga cacagacgac
    20761 accgacgctg aatccacggg tgaggccccg cgtccacggc tggctgaccg ttgactcgac
    20821 tcctgcccgc ccttggcatc cggcacctca gcgcatcacc caggggcata tcgcgtcgtg
    20881 atcatcgggt ggtcctggtg agatcctcga tccagatcat cgaggcgcgc aggtggagac
    20941 cggcgaggta gctgtcgagt gtctccggga tgaccgcctt gatacggcgt tcgcgcaggt
    21001 gggcgcggtt gccgcgggac gagtacgcct tgtccccggc gaccgcgtcc ggc
//
