LOCUS       NZ_CP065054            18828 bp    DNA     circular CON 17-MAY-2024
DEFINITION  Streptococcus equi subsp. zooepidemicus strain SEZ13 chromosome,
            complete genome.
ACCESSION   NZ_CP065054
VERSION     NZ_CP065054.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Complete genomes of eight Streptococcus equi subsp. zooepidemicus
            strains isolated from mares in estrus with endometriti
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2021) Microbiology, Immunology, and Pathology,
            Colorado State University, 2025 Campus Delivery, Fort Collins, CO
            80523, USA
  REMARK    Annotation added by submitter
REFERENCE   3  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2020) Microbiology, Immunology, and Pathology,
            Colorado State University, 2025 Campus Delivery, Fort Collins, CO
            80523, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Coverage                   :: 246
            Sequencing Technology :: Illumina NextSeq;Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015689395.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 02:47:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,059
            CDSs (total)                      :: 1,970
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 16 of 37
            Pseudo Genes (incomplete)         :: 20 of 37
            Pseudo Genes (internal stop)      :: 16 of 37
            Pseudo Genes (multiple problems)  :: 14 of 37
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:11:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1660044
            Orig. end                         :: 1678872
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065054.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..18828
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="8"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..18828
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18828
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:13828]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..13828
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(169..642)
                     /db_xref="GeneID:83705871"
                     /locus_tag="I2432_RS10350"
     CDS             complement(169..642)
                     /codon_start=1
                     /db_xref="GeneID:83705871"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I2432_RS10350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_231151225.1"
                     /transl_table=11
                     /translation="MAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQL
                     IGSVIALTVLAIAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLF
                     LAIGMMGILTGNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            complement(694..2172)
                     /db_xref="GeneID:83705376"
                     /locus_tag="I2432_RS07810"
                     /old_locus_tag="LJFMMFNO_01564"
     CDS             complement(694..2172)
                     /codon_start=1
                     /db_xref="GeneID:83705376"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I2432_RS07810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LJFMMFNO_01564"
                     /product="ABC transporter permease"
                     /protein_id="WP_231151224.1"
                     /transl_table=11
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASNK
                     DVDKGHVLDRIEALVEQEHIQIYRPYLDHTGKEATYLFGTNGKKTAYSSNRKELLTNDL
                     SGMYYTTRSLPSSFETAMTELGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVFALL
                     LFAVKLMYAKKSMIQRSLGLFEHYSRRELLQDLLLMGASFAVSILLFILYQGSISNVFV
                     KSFTLLMLTNAVILLLLMLAVHALFFINIRSLKALAILKNKRATPLVLFVWLVGICLSS
                     VIFGLSLHKSLETIGKSANDIQVLGKWDTAKDFAEITWLETLSAHTDENHQIDSDYLKE
                     ENQRYQHFLLSFSDSEVIYSEPSSLNETNLQSAPDDFKKELKTNGVDPRIASKVRYVNQ
                     GFMLKNKDIFPNNDYGRPAADVAGVIYIPKHMMGDADSILNIVNYEWFQYSSLKANQLV
                     VQEVPNGQKSFLFNHKEDQQDIFAQQEEVDTILV"
     gene            complement(2241..2366)
                     /db_xref="GeneID:83705889"
                     /locus_tag="I2432_RS10440"
     CDS             complement(2241..2366)
                     /codon_start=1
                     /db_xref="GeneID:83705889"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I2432_RS10440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255313937.1"
                     /transl_table=11
                     /translation="MTEFWGNVNSKDSQNNGWARAGVKKQWNWVQAKSCYGWYQV"
     gene            2890..3075
                     /db_xref="GeneID:83705377"
                     /locus_tag="I2432_RS07815"
     CDS             2890..3075
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705377"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /locus_tag="I2432_RS07815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_255313988.1"
                     /transl_table=11
                     /translation="MRQNKGLSQAIIGEVISRQSLISFEKGESTPRYETMMFLLRQIDM
                     TFGDVEDSYTEIERVL"
     gene            complement(3177..3758)
                     /db_xref="GeneID:83705378"
                     /locus_tag="I2432_RS07820"
                     /old_locus_tag="LJFMMFNO_01565"
     CDS             complement(3177..3758)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /db_xref="GeneID:83705378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /locus_tag="I2432_RS07820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01565"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_043031274.1"
                     /transl_table=11
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVSFEYTVPSLTKFEQRLS
                     DIMAFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYHRL
                     EGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWFDMI
                     WMEKLLGEHDVRPRPVMSFRDLLCQKHQSE"
     gene            complement(4009..4410)
                     /db_xref="GeneID:83705379"
                     /locus_tag="I2432_RS07825"
                     /old_locus_tag="LJFMMFNO_01566"
     CDS             complement(4009..4410)
                     /codon_start=1
                     /db_xref="GeneID:83705379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /locus_tag="I2432_RS07825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01566"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_249093179.1"
                     /transl_table=11
                     /translation="MKRLHYLMIFRLLTGQLPAIGLMAVLLSKAIHRLSFGSLISFAIF
                     AVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSSSEFYKQ
                     VIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            complement(4705..5001)
                     /db_xref="GeneID:83705380"
                     /locus_tag="I2432_RS07830"
                     /old_locus_tag="LJFMMFNO_01567"
     CDS             complement(4705..5001)
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623338.1"
                     /locus_tag="I2432_RS07830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01567"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_111678339.1"
                     /transl_table=11
                     /translation="MSALNWFSGGKARRTEALLLLKELMILLSEQENKQSLYQIIYHFS
                     NELASGGTSVPLVLSELNVALSAIMVKESLQLTKKETQLLKQLRQLSHVRYGY"
     gene            complement(5001..5189)
                     /db_xref="GeneID:83705381"
                     /locus_tag="I2432_RS07835"
     CDS             complement(5001..5189)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705381"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_II"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057644.1"
                     /locus_tag="I2432_RS07835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="leucocin A/sakacin P family class II bacteriocin"
                     /protein_id="WP_229297300.1"
                     /sec_met_domain="Bacteriocin_II (E-value: 5.3e-17,
                     bitscore: 58.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDADKLAHVEGGKTTYYGNGLYCNTQKCWVNWSEAVNIILNNSV
                     MNGLTGGNAGWHSGGII"
     gene            complement(5948..6244)
                     /db_xref="GeneID:83705382"
                     /locus_tag="I2432_RS07840"
                     /old_locus_tag="LJFMMFNO_01568"
     CDS             complement(5948..6244)
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /locus_tag="I2432_RS07840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01568"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_111678854.1"
                     /transl_table=11
                     /translation="MLTREEILNKVYNLILDPTLTSEERVILIRFKDRVGESNSFDREV
                     MMLSESLHQLAVKQIRVETMSIEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(6251..6499)
                     /db_xref="GeneID:83705383"
                     /locus_tag="I2432_RS07845"
                     /old_locus_tag="LJFMMFNO_01569"
     CDS             complement(6251..6499)
                     /codon_start=1
                     /db_xref="GeneID:83705383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /locus_tag="I2432_RS07845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01569"
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="WP_111678341.1"
                     /transl_table=11
                     /translation="MNTTLTKQFDIIDTDKLAHVEGGGKGNCQFVMAGSNGYACRYSNG
                     EWGYIVTKSNVEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            6758..8914
                     /db_xref="GeneID:83705384"
                     /locus_tag="I2432_RS07850"
                     /old_locus_tag="LJFMMFNO_01570"
     CDS             6758..8914
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705384"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205155.1"
                     /locus_tag="I2432_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01570"
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="WP_111678343.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.2e-41, bitscore:
                     137.1, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1114.7,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKT
                     NKEGTTALGIVMAAKEIGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVYKS
                     KKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFPLIF
                     KQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQL
                     MSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALA
                     STILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMNHDVMQS
                     NAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGA
                     QLILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNR
                     LNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLV
                     GVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQQAYVFNGSIL
                     ENLTLGAKQGISQEDILKACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARA
                     LLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQG
                     QIIETGSHQELMKQGGFYYHLFSE"
     gene            8925..10283
                     /db_xref="GeneID:83705385"
                     /locus_tag="I2432_RS07855"
                     /old_locus_tag="LJFMMFNO_01571"
     CDS             8925..10283
                     /codon_start=1
                     /db_xref="GeneID:83705385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /locus_tag="I2432_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01571"
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="WP_111678345.1"
                     /transl_table=11
                     /translation="MNPNMFKSAEFYQRRYYHLTTFLTIPLALLLTFLILFSCFTYKEI
                     TVTSYGEITPTQVIATVQSISNNPIIANHLINNQPIKQGDSIIQYAKDLEESQKQVLEK
                     QLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIKAET
                     CQQAQLIQDSIVAINQQINSLSQQIADYEELRAAVINQSDSLSSNNPHQATLDAYLSQS
                     QASQEAATNQLLFQIDQSLLNLKASMDSLNRQRANLHQSTSYDNSLNTKLEILRTQFLI
                     TASQQLTDVNHHITELKAQLEQATLQVNSLVIKAPKSGIVQLNSAFEGKTSIPIGHDIA
                     YIYPSLKQTKQALLTYYVSSESVSLLKKNQIVRLALDRHGNQPIVITGTIKTIDELATK
                     TKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKVTE"
     gene            10383..10517
                     /db_xref="GeneID:83705386"
                     /locus_tag="I2432_RS07860"
                     /old_locus_tag="LJFMMFNO_01572"
     CDS             10383..10517
                     /GO_function="GO:0005186 - pheromone activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623342.1"
                     /locus_tag="I2432_RS07860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01572"
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="WP_012516117.1"
                     /transl_table=11
                     /translation="MDKPTRQSKFQELTPSQLTQITGGGWLEDTINNFLIPRKKLLEW"
     gene            complement(10636..11970)
                     /db_xref="GeneID:90427716"
                     /locus_tag="I2432_RS10475"
                     /old_locus_tag="LJFMMFNO_01573"
     CDS             complement(10636..11970)
                     /codon_start=1
                     /db_xref="GeneID:90427716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /locus_tag="I2432_RS10475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01573"
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_111678347.1"
                     /transl_table=11
                     /translation="MKFILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGFA
                     VFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRLLG
                     FFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKRILG
                     VTNWSMVSYYFLIQLLAYLEYELAVDTYTYRQCMMLGYWIIFMGTVARLDRSLRDTLQE
                     RLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNNNMSIVRSVYQS
                     VFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEASSPQGME
                     LIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKIDLSFLYDF
                     GVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(11970..12719)
                     /db_xref="GeneID:83705387"
                     /locus_tag="I2432_RS07870"
                     /old_locus_tag="LJFMMFNO_01574"
     CDS             complement(11970..12719)
                     /codon_start=1
                     /db_xref="GeneID:83705387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /locus_tag="I2432_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01574"
                     /product="response regulator transcription factor"
                     /protein_id="WP_111678349.1"
                     /transl_table=11
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLS
                     AIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQVS
                     ALDYIDKELPHTEFVQRVETALLYAVRQNSETIVESAFYFTSRYAQVQVPFNDILYIET
                     SSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVKVDKIERVVYFR
                     NGSSCLIARSKMNSVLTTIENLHRGDD"
     misc_feature    12980..12993
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.7"
                     /tool="antismash"
     misc_feature    complement(13036..13051)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            complement(13351..13554)
                     /db_xref="GeneID:83705388"
                     /locus_tag="I2432_RS07875"
                     /old_locus_tag="LJFMMFNO_01575"
     CDS             complement(13351..13554)
                     /codon_start=1
                     /db_xref="GeneID:83705388"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /locus_tag="I2432_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01575"
                     /product="TmhB bacteriocin enhancer peptide"
                     /protein_id="WP_111678351.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6.6e-11,
                     bitscore: 39.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSGP
                     LYVLGAGIGSTVGAGQAIINGL"
     gene            complement(13571..13828)
                     /db_xref="GeneID:83705389"
                     /locus_tag="I2432_RS07880"
                     /old_locus_tag="LJFMMFNO_01576"
     CDS             complement(13571..13828)
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705389"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /locus_tag="I2432_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01576"
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_111678353.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.5e-19,
                     bitscore: 65.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSGA
                     LWGAPAGGIGALPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(14304..14585)
                     /db_xref="GeneID:83705390"
                     /locus_tag="I2432_RS07885"
                     /old_locus_tag="LJFMMFNO_01577"
     CDS             complement(14304..14585)
                     /codon_start=1
                     /db_xref="GeneID:83705390"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I2432_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LJFMMFNO_01577"
                     /product="hypothetical protein"
                     /protein_id="WP_206158717.1"
                     /transl_table=11
                     /translation="MKLREYFVKRLISSFCLIVLLGVLVVVNAEENITSKEDYYLDFHD
                     EFDGDSLARTKWTGCYLSHWTFNPKNAKTNYRFEDRKFIDYIAEDQKI"
     gene            complement(14601..15926)
                     /db_xref="GeneID:83705391"
                     /locus_tag="I2432_RS07890"
                     /old_locus_tag="LJFMMFNO_01578"
     CDS             complement(14601..15926)
                     /codon_start=1
                     /db_xref="GeneID:83705391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722668.1"
                     /locus_tag="I2432_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01578"
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="WP_111678855.1"
                     /transl_table=11
                     /translation="MGHKFVMVGGGSTQSPGILEVLRQRSEELRLTDLVLYDIDEERVS
                     LLGQYTKMYYAETGSTVNVSYTTDIDEAFTGADYLFMQIRPGLNRQRAIDEKICIRNGV
                     VGQETCGLGGFSFAMRVIPAVMDIIRKVKELCPNAWILNYTNPEAILSEAIYREFPEAK
                     VLCICDMPISIEGAIAKYFNKDLRDLTFKYFGLNHFGWWTNIYDENGNDLLPILREDVV
                     SGKIDTLLQSNEETKADQYWIDTYKQMISLFKRFPDYFPNCYLQYYLTPDEMLAHDDVN
                     FTRGDYVIQGREKRIYEECRRVIASGTAKNSSLHAGVHGNYIVDIAYSIIHNTRERFTV
                     NKKNHGAISNFDPEAVVEVPAYVGSMGAETINIGSIPPLQKGLMEMQKAYEKKTVDAAL
                     TGSYQTALEAVMLNKTIPNYTVGKKVLDELYEANKDFWPVLK"
     gene            complement(15946..17496)
                     /db_xref="GeneID:83705392"
                     /locus_tag="I2432_RS07895"
                     /old_locus_tag="LJFMMFNO_01579"
     CDS             complement(15946..17496)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83705392"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769291.1"
                     /locus_tag="I2432_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01579"
                     /product="PTS transporter subunit EIIC"
                     /protein_id="WP_111678357.1"
                     /transl_table=11
                     /translation="MKERMMKSASVFSKAIIQPVMFMAVTGIVLSICAILKLDFMPEFT
                     KNIGNFIFDILSGGMIGQLSVIFSVGIATALAKRKYKTDAAILGIVTFLIFLYANNSWL
                     TLTNRLAEAGEFGLYGTGQGMVFGMQVVDMGVFLGIMLGCFVGVMVNKFGEIKLHKYLA
                     PYEGTKSVYIILIFLTILLAIVTTYIWPVVNGIVESVVATTTTAGSLGFFFYGFLNRML
                     LPLGLHHFLWMPLFYTPLGGTAEIAGQMQNGAFNIWLAELGNAGSIISMHSSIGYLSNF
                     GSISLPIGIAFALWKTAKSKNRKKVASILIPTVVTAFMAGITEPLEFLFLFLSPVLWLA
                     HAIVYGLSLLITNLIGISIQFDTGINMIINSFAFPLSLGKQYWIPVVFVITAVIEYLVF
                     RYLIVKLNIPTLGREDMADDEEQDEMTTIQTTAKVVKSNDQVEKIVAGLGGKDNISSII
                     NCYTRLRVDIKDETKLDMNILKNQVKSSGIVDKGKHIQIVIGLGVETIREEIENYLNS"
     gene            complement(17512..18300)
                     /db_xref="GeneID:83705393"
                     /locus_tag="I2432_RS07900"
                     /old_locus_tag="LJFMMFNO_01580"
     CDS             complement(17512..18300)
                     /codon_start=1
                     /db_xref="GeneID:83705393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722670.1"
                     /locus_tag="I2432_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_01580"
                     /product="carbohydrate deacetylase"
                     /protein_id="WP_111678359.1"
                     /transl_table=11
                     /translation="MKKVIINADDFGYSPAVNAGIIKAFQDGILTSTTLMANMPGCDEA
                     IMLAKENPDLGVGVHMVLTCGESMTKGKTISQQGKFYSLKNYHENRFKIDDEEIYQEWC
                     CQIDYLLDEGLKPTHIDSHHHLHTFPENLLISQRIAQRYGLPLRNAYGLEINIDLPNQI
                     GATGFFDLTNYPHIRDLSKSIESDKIACLTEVEKLLDQIEDNTITELMVHPAYVDEILY
                     FNSSFNIARVKEVSLLCDQDVAQLFKDFNIQLYHYGNITF"
     misc_feature    18461..18476
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
ORIGIN
        1 tctgaccgct atctggcttt tcaaggcgag caatagcatt taatagggtt gtcttgcctg
       61 atcctgaagg acctacaagt gcataagaac gattggcctc aaaagtcaag ctaatcttgt
      121 cataaattgt cttttttcca taatgtttgg aaagctgttt tatctcaatc ataatatgtc
      181 aaaatctcct ttgatgattt gaatccgatg cttcaaaata gcctgataag caaaaaagga
      241 catacaaacg atttctccta aataaagcag gccaatgcct agtaccatga gcctatttcc
      301 agtaaggatt cccatcattc ctatggcaag aaacaaacac aaagctaagg gcaataacaa
      361 tctaccaatc aaaacaaggc ttttttgccc catcaagaac cagacggaaa tctttttggc
      421 cttttgtttc atcagagaaa caatgtattc ataaatgata aagcactggg caatggcaag
      481 gaccgttaag gcaataacac ttccgatgag ctggcttagg attttatggc gctctaaaat
      541 caaatgattg gaaacattgg tcaaactgga gaaattcgtc aagcctgctt gtgttaatcg
      601 atcacgaata agcgcctgac gatagataga tttttgagcc atttctccaa acttcgtcag
      661 taatgatggc tccatcatga acgaaaagtt taactacact aatatagtat ccacttcttc
      721 ttgctgagca aaaatgtctt gttggtcttc cttatgatta aaaagaaaac tcttttgtcc
      781 gttaggaacc tcttgaacaa ccaattgatt agcctttagg ctgctgtatt gaaaccattc
      841 ataattgaca atgtttaaaa tgctgtcagc atctcccatc atatgtttag gaatataaat
      901 gactcctgca acatctgctg ctggccttcc gtaatcattg ttaggaaaaa tgtctttatt
      961 ttttagcata aatccctgat tgacataacg gacttttgac gcaatccttg gatcaacccc
     1021 attggtcttt aactcctttt tgaagtcatc aggagctgat tgtaaattgg tttcgttaag
     1081 gcttgaaggt tctgaataaa taacctcact atccgaaaaa gacaggagaa aatgttgata
     1141 gcgctgattt tcttccttta aataatcact atcaatttgg tgattctcat cagtatgagc
     1201 actcagtgtc tctagccatg ttatttccgc aaaatcctta gctgtatccc attttcctag
     1261 aacttgaatg tcattggcag atttacctat agtctccaag cttttgtgta gagaaagccc
     1321 gaaaatgacg ctagacagac aaatccccac caaccagaca aagaggacca gaggggttgc
     1381 tcgtttattt tttagaatgg ctagcgcctt caacgaacgg atattgatga aaaataaagc
     1441 atgaacagca agcatcagca ataataaaat gacagcatta gtcaacatca gaagtgtaaa
     1501 tgacttgaca aaaacattgg agatactgcc ttgatagaga atgaagagga gaatactaac
     1561 cgcaaagcta gctcccatca gcaacaaatc ctgtagcaac tctctacggc tatagtgttc
     1621 aaataagccc agacttcttt gaatcataga ctttttagca tacatcaatt taacagcaaa
     1681 caagaggaga gcaaacacaa aaaagagggt ccaaatagct aaggatcgta agtttgtgaa
     1741 caaaaaataa taaggcaaga gataccaagg taaatcagca cctttgtagg tcaagcccag
     1801 ttcagtcatc gcggtttcaa atgatgaagg aagagacctc gtcgtgtagt acatgccact
     1861 aagatcgttt gtcaagagct ccttgcgatt actgctatag gcagtctttt tcccatttgt
     1921 cccaaacagg taggtagctt ctttaccagt atgatctaag tagggacgat aaatttggat
     1981 atgttcctgc tcgactaagg cttcgatcct gtctaaaacg tgtcccttat caacatcttt
     2041 gtttgaagcc actaatgaaa atgcagcctg aacagggtat ttgatatcat tgccatactc
     2101 cttgaccgca ccaaatgata aacatgtcaa aagcagaacg aaaatacaga taactgtagc
     2161 tctccacctc ataaaaacct ccttgagaaa agttgactaa gaggataata tcttagtcaa
     2221 ctaaaacgta caataaaaca ttaaacctga taccagccat aacatgactt tgcttgaacc
     2281 caattccact gcttttttac accggcacga gcccaaccat tgttttgact atctttacta
     2341 tttacatttc cccaaaattc tgtcacagaa gcactacttc ctagcctaat aggaactcca
     2401 agaaaagcgt ttgagtaaga tcagctagca ctggtcattc cagatctcca agtatcctta
     2461 catcttaggt aagggtggct agcttctaca ccaaaatcag ttatcccagt ggctgacgtc
     2521 aaggttatag atcattttac acttctgttc atactatatc ttttctttta ttaaaataaa
     2581 gtaaacataa gcttaattcg tatcagaatc tttttacaat acaactatac catattataa
     2641 aaggtttttt ggatagcgtt taagtttttt ttgcagctca ttaacagaat tttcaagggc
     2701 aaaaaaaaga tattaaaaag acaaagctta aaaaataaca tttatttcct catcaaatct
     2761 tcctttatgg cgtttagatg atgctattgt cataaaaagt gcagggaata atccgttttt
     2821 ctacactatt tattagtaat ttcaaaggag gcaaggttag gagagagaag cctgcgctat
     2881 tacaagaaca tacgacaaaa taagggatta tcacaggcaa tcattggaga agtcatcagc
     2941 agacaaagct tgattagctt tgaaaaaggg gaaagcactc ctcgctatga aactatgatg
     3001 tttctattga gacaaattga catgactttt ggggacgttg aagacagcta cactgagatt
     3061 gagagagtgt tatgattgcg gttaccagcc aaggcttctc gtaaaaaaat acaaaaaaat
     3121 tagcttcctc tgataggacc taatcctttt gtattaatct aagcttttat aaggtgtcat
     3181 tcagactgat gcttctggca aagaagatct ctaaatgaca tcactgggcg agggcgtacg
     3241 tcatgctctc ccagcagttt ctccatccaa atcatatcaa accactggtt aaacttatag
     3301 cccgactgat gaaatctgcc aaccaaccga taaccgagtt tttcatggaa gacttgactg
     3361 ctattggtca gataaggcgt agcatgcgct gtactagcga tacaggcatt acaatttaaa
     3421 attcccatgc ctttcagata gccctccaaa cggtgataca aggctgatcc caagcctctc
     3481 cctctagcct cctgggccag ataaatggtc acctcagcag accaagcata ggctgcgcgt
     3541 gcatgaaagc gactagcata ggcataacct aaaatgcctc cctcctcttc cactactaga
     3601 cagggataaa aggccataat gtcagacagg cgttgctcaa acttggtcaa gctaggtaca
     3661 gtgtactcaa agctaacagc agtttcctca acataaggac ggtaaatatc aagtaaagcc
     3721 ttagcatctg ctaaggttgc taaacgaatc ctacgcatta atagccctcc tagttttccc
     3781 agtatactcc aaaacaaggg ccttgtcaaa agcactgata gtaaaaaagc ctgatcccta
     3841 aacgaaatag gttgtcatat cgcttgcaga tagacagctc taccccctca aaagctattt
     3901 taagcgtttg agcacacaaa cactaggtat cgctttaagg ctgataccta gtgctatagc
     3961 ttatgattaa ctggttaagg aggtgattcc aagtaccacc tcaagctatt aacgacgata
     4021 agcttttgcg tatctgatcc cccaaatcat caatcccata gtgacaaatg atataaaaga
     4081 gcatatcaca gcaataacct gcttataaaa ctcagacgag cttagaccac aatagattga
     4141 cacaatgcct ataatcataa acaccactat aaacaggatc tgagttaata acagattggg
     4201 acgtgtttgt tctttcaact gctcaatcgc aatttctcgt gaaaaatagt aattagaagc
     4261 agcagtgctt accgcaaaga tagcaaaact aatcagtgat ccaaaagaaa gcctatgaat
     4321 ggcttttgaa agaagaacag ccatcaagcc aatagctggt agctgaccag ttaatagcct
     4381 aaaaatcatc aaataatgta gtcgcttcat tttattaagc attacaacac cttgcccttt
     4441 cttagcaagt cagtgcgcca cctattcctc caatagctgc gtcacaaact ctattaattt
     4501 tttcagcctc aacataagca agtctaacag tacctaagca ttaaatattt catcaatgct
     4561 gtcgtccaca tgaatacttc ctatgtttag caaccggcac cagtatagca gataaacaat
     4621 cgctttcagt atttaagtct taaaatgtcg tcgaagcgtc ttgaatggta atacgaaaac
     4681 cgttgacacc agttaagcgc atttctaata cccataacga acatgagaaa gctgtcttaa
     4741 ttgcttcaaa agctgggttt ccttctttgt gagctgaagg ctctctttta ccattatagc
     4801 tgacagtgca acgttcaact cactaagtac caaaggaact gaggtgcctc cagaagccaa
     4861 ctcattagaa aagtgataaa taatctgata aagagattgc ttgttttcct gttcagataa
     4921 gagtatcatc aattccttca gcaataaaag tgcttctgtc cttcgagctt tcccacctga
     4981 aaaccagttt aaagctgaca tcagatgatt ccccctgaat gccaacctgc attcccaccg
     5041 gtaaggccat tcatcacaga attgtttaat atgatattaa ctgcttctga ccaatttacc
     5101 caacactttt gcgtattaca atataagcca ttcccatagt aagtagtctt tccaccctca
     5161 acgtgagcaa gcttgtcagc gtctataata ttaaattatt tcattaatgt cgtattcatt
     5221 gtgaatacct cctatcttta ttttttgtct gttgcaactg acaaacccag tatagcagat
     5281 aaacaactgc tttcaacgct tagtcttgaa atgtcgtcga aacgtcttga atggtaatac
     5341 gaaaaccgtt gacaccaatt cagtgaaaat tcctaatacc cgtaacgaat atgagaaagc
     5401 tgtcttaatt gcttcaaagg ctgagattcc ttctttgtga gctgaaggct ctatactgta
     5461 atgacaaata gccaaacctt aaatagctat tttatttttc cagatagcaa tacgtcatca
     5521 acagctgatg aaaataatac atttgtggcc tcagcttact aacttaagcc tctagaaata
     5581 aggaaaagca actgatttga tagctaatag cgcagataat atttcttttc caagctcaat
     5641 aagactcaaa aataagttct ttgtaagaaa aaataaatca ctaaccaaat gagataagct
     5701 tattgccctt gcaattatcc caagctactt cttgtccgaa gccaccctag atagttaact
     5761 accacaaaac aataggtatc agctttaaac cgatacctat tgttatatcc tgcgattagc
     5821 caatcaactc aatcgttact tactttacct ttagctagcc atctcacaaa atagcaataa
     5881 cagtcttttc atgtcgtttc gcctattaac aataatacca atacaacaat aaggtatgag
     5941 cgttttatta tcgcctaata actcccaatg atattaggcc tcgacctagc tgtttatcac
     6001 attctttgta agtagagatt tctttataga atttagccat ttctatactc attgtttcaa
     6061 ctcttatctg cttaacagct aattgatgca gagattcaga cagcatcatc acttccctgt
     6121 caaagctatt tgactcccct actctatctt taaatcttat cagaatgact cgctcttctg
     6181 atgttaaggt cggatctaaa attaaattat aaaccttatt tagtatctct tctcgcgtca
     6241 acatacccaa ctaccctcta tagcctggat ggaaataacc acctcctaaa gatgatatcc
     6301 aaccgttaac aataacatct ttagttgctt caacattact tttagtgaca atatagcccc
     6361 attcgccatt gctatatcgg caggcatacc cattagaacc ggccattaca aactgacaat
     6421 ttcctttgcc tcccccctca acgtgagcaa gcttatctgt atctataata tcaaattgtt
     6481 tcgttaatgt cgtgttcatc gtgaatacct cctatattta ctttttgtct gctacaactg
     6541 ataaacccag tatagcagat aaacagctgc ttttaatgct tagtcctgaa atgtcgtcga
     6601 agcgtcttga atggtaatat cgcagctgat taaaaaagag tgttaatatc attattccca
     6661 tttaagacgt ttcaacgact attcaagact agctcagttt ttttctgagc ttttgtggca
     6721 caatagagtc gttacaacag agaaaggaag ccaaccaatg acactctttt ataaaagaac
     6781 ctttgtacca caaatagatg ccagagattg tggcgtagct gctctagctt cgatcgcaag
     6841 gtattatggt tcagattatt cattagctca tttgagagaa ttagcaaaga ccaataagga
     6901 agggacaaca gccctcggta ttgtcatggc tgctaaggaa atagggtttg aaaccagacc
     6961 cattcaagcg gatatgaccc tctttgacat ggcagatgtg ccctatccat tgatcgtcca
     7021 tgtcaataaa gaaggaaagc tacagcacta ctatgtggtc tacaaatcta aaaaagacta
     7081 tcttatcatt ggtgatcccg atccaatggt caaggtcaca aaaatgtcca aggaacgctt
     7141 tgcttctgaa tggacaggtg tcaccatatg tcttgctcct aagccaaatt ataaaccaca
     7201 taaagaccaa aaaaatggac tattaggctt ctttccactt atttttaaac agcgagccct
     7261 tattttttat atcgtgttag cttctgtctt ggtaacggtc attaatattg ctggttcata
     7321 ctatctccaa gggattttag acgagtatat tccaaatcaa ctgaaatcta ccttagggat
     7381 tgtatcaatt ggtctcatca ttacctatat actccagcag ctaatgagct tttctagaga
     7441 ttatctttta actgtcctta gccaacgtct tacgattgat gtgatcctgt cctatatccg
     7501 ccatattttc gaattgccga tgtccttttt tgcaacacgt cgaacaggtg aggtaacctc
     7561 gcgctttaca gatgctaact ctatcattga cgcactcgct tcaaccattt tatctctctt
     7621 tctagacctc tctatattag ctattgtcgg aagtgttctt ttggtgcaaa atagcaggct
     7681 ttttctgtta tctctgattt ctatcccagt atataccatt atcatatgtg cctttataaa
     7741 gccgtttgaa caaatgaatc atgatgtgat gcaaagcaat gccatgctaa gctctgctat
     7801 tatcgaagat atcaacggga tcgaaaccat aaaatcacta accagtgaag aaaaccgtta
     7861 ccaaaaaatt gacagcgact ttgtggatta cctcgataag tcctttaggc ttagtaaata
     7921 taccatctta caagccacac ttaagcaagg agcgcagcta attctgaata tcatcattct
     7981 ttggtttggg gctcaactgg ttattaatgg taggatttca atcgggcagt taattacctt
     8041 taacacactt cttgcctatt ttacaacccc tttagaaaat atcattaatc ttcaaaccaa
     8101 gctccaagca gctaaggttg ccaacaatcg tctcaatgag gtctatcttg tagagtccga
     8161 atttaaagcc tcgcaagcct tatacgattt atcgctctta cagggtgaca ttcagtttga
     8221 agctgtttcc tacaggtatg gctttggcaa ggatacatta tcagatatta cattaaccat
     8281 taagcaggga gcaaaagtaa cccttgttgg tgtcagcggc tcaggaaaaa caaccctagc
     8341 caagatgctc gtcaatttct ttgagcctta taagggacgt ataaccatca accaaaatga
     8401 tctcaagacc attgataaaa agaatcttcg acaatacatc aactaccttc cacaacaagc
     8461 ctatgtcttt aatggatcta tcttagaaaa tctaaccttg ggagccaagc agggcatcag
     8521 ccaggaagac attcttaaag cctgtgagat tgctgacatt cgtcacgaca tcgagcaaat
     8581 gccaatggga taccaaaccg agctctctga tggggctggc ttatctggcg gacaaaaaca
     8641 gagaattgca cttgctagag cattactaac ccaagctcct atactagttc ttgatgaagc
     8701 aaccagcgga cttgacatac tgacagaaaa gaaaatcatt gaccgtctca tgaacatgac
     8761 agacaaaacg attattttcg ttgcccaccg gcttagtatc gcagagcgca ctgatcaggt
     8821 tgtggttctt aatcaagggc aaatcattga aacaggcagc caccaggaat taatgaaaca
     8881 aggtggattt tattaccacc tatttagtga ataaggagac aatcatgaat cccaatatgt
     8941 ttaaaagtgc ggaattctac caaagacgct attatcattt gacaacattc ttaacaatcc
     9001 ccttagccct cttgttgact tttcttatcc ttttttcttg ctttacttat aaagaaataa
     9061 cggtaacgtc ctacggagaa atcactccca ctcaagtcat tgcaacagtc cagtctatta
     9121 gcaataaccc tataattgcg aaccatctca tcaataacca gccaatcaaa caaggagact
     9181 ccattattca atatgctaaa gacctagaag agtctcaaaa gcaggtactt gagaaacaat
     9241 tagctaccta cgaaaagcaa aaaagcagcc ttaatactct attgttaagc ttaaaacaag
     9301 gccagaacct ttttcagaac gatgatcaat ttggttacgt caataccttt aatcatttca
     9361 tgagccaagc ccaagatatt gaccttggtt tctcaaaaat aaaggcagag acctgccagc
     9421 aggcccagct gattcaggac tctattgttg ctatcaatca gcaaataaat agtctttctc
     9481 aacaaatagc agattatgaa gagcttcgag ctgcagtcat taaccaatcc gatagtctat
     9541 cctccaataa cccacatcaa gccacccttg atgcctatct ctctcaatct caagcaagcc
     9601 aagaggctgc cactaatcag cttttatttc aaatagacca aagcctttta aatctaaaag
     9661 cttctatgga tagccttaat aggcaacgtg ctaatctgca tcaatctacc agctatgata
     9721 atagcctcaa cacaaagcta gaaatactcc gaacacagtt tttgataaca gcctctcagc
     9781 agttaacaga cgtcaatcat catattactg agctcaaggc acaattagag caagccactc
     9841 ttcaggtaaa cagtctagtg atcaaagccc ccaaaagtgg cattgttcag ctcaatagtg
     9901 cttttgaagg caaaactagt attccaatcg gtcatgatat tgcctacatt tatcctagcc
     9961 tcaaacaaac aaaacaagcc ttgctcactt actatgtcag ctctgaatct gtttctctcc
    10021 ttaagaaaaa ccagattgtc agactagctc tagatagaca tggaaatcaa ccgatagtca
    10081 ttacgggaac cattaaaacc attgatgagc tagcgaccaa aaccaagcag ggaaatcttt
    10141 ttaaggttac agccaaacta acactttctg aaaaagaaag cactactatt caatatggtc
    10201 agcagggacg agtgataagt gttattgcca aaaaaacatt ctttgacttt tataaggaca
    10261 agctctttaa agtgacagaa taaccattta gcgcttttca acgaccattt aggacataca
    10321 gtataacaaa gagtcaaaat aagctataat aacatagaca gtatttaaaa ggagctttta
    10381 atatggataa accaactaga caatcaaaat ttcaggaact aacaccttct caattaactc
    10441 agattactgg aggaggctgg cttgaagaca ctataaataa cttccttatc cctagaaaaa
    10501 aactattaga atggtaacat tctccctttt caaaacacca ctatctaaag atactgagac
    10561 actatcggaa tgatgtgatc ctaaacatca aatctgagag gtgtaagaca gtttttcttt
    10621 actagtggtg tttttttata acctaagctc aagtgtttga ccaaatacat gattttgact
    10681 tatggttttt atcatcacat tgggataacg attgataatt tccatagcat tataaagtcc
    10741 cacacctcta ttatccccct tggtgcttac tccgaaatca tatagaaagg atagatcaat
    10801 cttctcttcc ttagttgtat tttcaatcat aaatagttgc ttattgtcca aagtaaaata
    10861 agaaatcgtt atcttagacg aggaagcttc aacagcagcc tctatagcat tatcacataa
    10921 aatagacaca atagtaagaa aatcaatcag ctccatgcct tgcggactac tagcctctgg
    10981 aacctctaag gatactgaaa tcccactttc taaagcctga ctaaattttg cagctaaaag
    11041 acttttcaag gctgtgtcag tgacatggat aagacgccca acatcatatt tttgcttgcg
    11101 aaatcgttta tttgaatcct taaagactga ttgataaact gacctaacaa tagacatgtt
    11161 attattgtct ataccaaact ttaacgtggc aatcagattg ctatagtcat gacgaaatcc
    11221 tcgaacctct ctgtaaagct cctctatctg acgactatag ctctcaatat ttgccagctg
    11281 cagctctctt tgaaaggtca gtctttcttg cagtgtatct cttagcgacc ggtccagtct
    11341 cgccacagtt cccataaata taatccaata gccaagcatc atgcattgac gataggtata
    11401 agtatcaaca gctagctcat actctaaata agcaagcaat tggatcaaaa aataatagct
    11461 aaccatagac cagttggtca cacctaaaat tcttttatcc ctatcagata aaagattaat
    11521 tcttaatgct ctgaaatcat atcgtagcca ccgcaaaaag agaaaaacca tcaaagtaga
    11581 tactatatct gtaaaaattc cccaaaatcc atcatttgtt aaatgataat caagtttaaa
    11641 aagaggtaag ataaaaaaac caagcagtcg gtaccaaagg ctccacaggg taataggaaa
    11701 tagcccataa aatatcaata atgtttttga taagggtcgc agcaatagcc atgatatcac
    11761 taccatataa atgggaagac tccaataatt gagaagtgaa atgtcggcaa catgattagc
    11821 tatagtgaaa aaaacagcaa atcctattct taaaaaagta ctgaaagcaa cttcaagcca
    11881 ggttaattga cgtccactga ttttggaaaa gagcactaac gataagccta tacttgtcgt
    11941 catttctaag aaaaataaaa taaacttcat taatcatctc ctctatgtag gttctcaatt
    12001 gttgttaaaa cactgttcat tttactacga gcaattaagc agctagagcc atttcgaaaa
    12061 taaaccactc gctcaatctt atctacctta acgacattcc taggattaat caaaaaagaa
    12121 cgatgacatt gcaaaaaacg agactcttgc ttcaaaatat ccgtcaaagt ccctgtaaat
    12181 tgcattctct ccttttttgt atacaaattg acacgatgcg ctcgtgacga tgtctcaata
    12241 tacaggatat cattaaaagg cacctgtacc tgagcataac gagatgtaaa ataaaaagca
    12301 ctttccacta tcgtttcact attttgccgc acagcatata ataaagcagt ctctacccgt
    12361 tgaacaaact cagtgtgagg cagctcttta tcgatatagt ccaaagcaga tacctgatac
    12421 tgaaaagcca agggcataaa ttccgagtga gtcgttacaa aaacaatcat cgcatctgga
    12481 tttatctgac gaatttgcct agcaacctca agcccttttt tgtcctcatt ttttatctca
    12541 atatctaaaa agaatagctg ctgaccacag ttcttcttga tagcacttaa tagctgatga
    12601 ggccttccaa aacagtcaag tccttgaaat aatagctggt gcttaacctc aagctcttta
    12661 atgagctttt ctaaatatct ctgctgaatc atatcatctt ctaaaataac tactctcacc
    12721 taaactcagt cccctatcca atctgcagaa gcattagcat tactaccgtt tcaacaaaat
    12781 aataagcaca ataacaaaaa taaatccatt aaaaacaact gcatcaaatc tcataaaaat
    12841 aatattttgt acttatttta gcataaaata ccatttttga atacactaat ctctaataaa
    12901 ctaatgctat ctagtcttag ctagcaataa cctagtgctt ctaacaacaa taatcagctc
    12961 aacaattttt agcagctacc tttttaaaaa aaagagactg ggataaaaag atttctcagg
    13021 taagaaaaat agagattcac caaacagtga atctctattt tttgaactga aactcctttt
    13081 gtcccaaact cataagatgt attgactttg tgagatgaac aatttgttac acttgatttg
    13141 atcatcggga tttagaaaaa atagtgaaaa gaatcctcat aattcgtgaa aaatataatt
    13201 tctcacccaa aaatccaatt caagattgta tttataagaa gtagcatgat taaagttata
    13261 gaaattctta tcaatacttc ttctttttta acaacactaa atatcaatag tataatcgga
    13321 actaaaacta atactactaa taatattgtt ttatagtcca ttgataatgg cctgtcctgc
    13381 accaacagtg cttcctattc ctgcacccaa tacatacaat ggaccagaga aagcacctgt
    13441 aacgatagct ccacctgcac aatgtcctgc aacagagccc caattaattt taccgccatt
    13501 tacacttgcc aagtcaagct cgtataacat ctgaaaatct tcgtactgct tcatggtata
    13561 tactcctttc ttagttaaat ctattaccta tcattccacc catacatgca aaacctcccc
    13621 caattgcacc aacatgtgcg ccaacaaatg cacctggaag tgcgccaatc cctcctgctg
    13681 gtgctcccca caaagcccca cttccagctc ctattaacat atatcctccc atgtctttaa
    13741 gacagtcctt accagaatat ccaccttcaa cagttgcaag agcctctata ttcataacat
    13801 caaattgatt aatcgtttct gtattcattt tgaatacctc cataacatat tttttctttg
    13861 tgtcgcgatc acgatttaag tatagcattc tagtatcata ttttttctaa aagtcttaaa
    13921 cggtcgtttt ttcatcgtaa acggtcattt tcaatcgttt tcaaccgttc aagacaaaat
    13981 taactaccat tcaggatttt cattggataa atcgctattt tttgactcct tgtcaaccca
    14041 ctaaagctat taataaaaaa ataagacagt agcctaaatg tgactactgt ctcttttatc
    14101 taaagccttg atcggcaaga aaagagccag tcttttccaa ctaatcgatt atttttgtgg
    14161 tttttgtcgc ttctgtagct tcactacagc ctcggtcctt ggtaattact catcgaagac
    14221 ttgcttctac taaaatgatg aatctaattt atattaaaac tcatagcggc attagaaaac
    14281 accgtttcgt ctagttctga tgactaaatt ttttgatctt cagcaatata atcaataaat
    14341 ttcctatctt caaatctata atttgtctta gcatttttag gattaaaagt ccaatgtgaa
    14401 agataacaac cagtccattt tgttctagct aagctatctc catcaaattc atcatgaaaa
    14461 tctaagtaat agtcttcttt agaagtaata ttctcttctg catttacaac tacaagtact
    14521 ccgagtaaga ctattaaaca aaatgaacta ataagtcttt tcacaaaata ttctctcaat
    14581 ttcaaataaa gtattagtga ttactttaaa acaggccaaa aatctttatt tgcctcataa
    14641 agttcatcga gcactttttt accaacagtg tagttcggga tcgtcttatt gagcatcaca
    14701 gcttctaaag cagtctgata tgatccagtt aatgctgcat caactgtctt tttctcataa
    14761 gccttttgca tttccataag ccccttttga aggggtggaa tgctaccaat attaatcgtc
    14821 tcagccccca tacttccgac ataagctgga acttcaacaa cagcttctgg atcaaagttt
    14881 gaaatcgccc catgattctt tttattaaca gtaaaacgct cacgagtgtt gtgaatgatg
    14941 gaataggcga tatccacaat atagtttcca tgaactccag catgaagtga agaattctta
    15001 gcagtccctg aagcaataac gcggcggcat tcttcataaa tccgtttttc acgtccttgt
    15061 atcacgtaat ccccacgagt gaagttgacg tcatcatgag ctagcatttc atctggtgtt
    15121 aagtaatact gtaagtagca attagggaaa taatcaggga atcgcttgaa caaactgatc
    15181 atctgtttgt aggtatcaat ccaatactgg tctgcctttg tttcttcatt agattgcagt
    15241 aatgtatcaa tcttaccaga aacaacatcc tcgcgaagta taggtaataa atcattccca
    15301 ttttcatcat agatattggt ccaccagcca aaatgattta gaccaaaata cttgaatgtt
    15361 aaatcgcgta gatctttgtt aaaatattta gcaatagctc cttcaatcga aatcggcata
    15421 tcacaaatac aaaggacctt tgcttctgga aattcacggt aaatagcttc agacaagata
    15481 gcttctggat tagtatagtt caagatccag gcatttggac aaagctcttt gaccttacga
    15541 ataatatcca tcacagctgg aatcacacgc atagcgaatg aaaatcctcc caaaccacaa
    15601 gtctcttggc ctacaactcc gtttcgaata cagatttttt catcaatagc tcgttggcga
    15661 ttgaggcctg gacggatttg cataaagagg taatctgctc cagtgaatgc ttcgtcaata
    15721 tcagttgtat aagatacgtt gacagttgaa cctgtctcag cataatacat ctttgtatat
    15781 tgaccaagta aagagacacg ttcttcatca atatcataaa gaaccaaatc tgttaacctt
    15841 aactcttcag atctttgacg taacacctct aaaattcctg gcgattgagt agaacctcca
    15901 cccaccataa caaatttatg tcccataatc atttctctcc ttttcttatg aattcaagta
    15961 attttcaatt tcttcacgta tagtttcaac accaagtccg ataacaatct ggatatgttt
    16021 acccttatct acaatacctg atgatttcac ttgatttttt aggatattca tatccaattt
    16081 agtttcatct ttaatatcaa ctcgtaaccg tgtatagcag ttgataatgc tagaaatatt
    16141 atcttttcca cctagaccag ctacaatttt ttcaacctga tcattgcttt ttacaacttt
    16201 agctgtcgtt tgaatagtcg tcatttcgtc ttgctcctca tcatctgcca tatcctcacg
    16261 acccaaggtt ggaatattaa gtttaacaat aaggtatcgg aaaacaaggt actcaataac
    16321 agcagtaatt acaaatacca ctggaatcca gtattgttta ccaagggata atgggaaagc
    16381 aaaactgtta ataatcatat tgatacctgt atcaaactgg atggagatgc caataaggtt
    16441 tgtgattaag aggcttaatc cataaacaat agcatgggcc aaccaaagta cgggtgacaa
    16501 gaataggaat aagaattcaa gcggttctgt aatacctgcc ataaatgctg taacaactgt
    16561 tggaatcaga attgaagcca ctttcttacg atttttagat ttagccgttt tccaaagagc
    16621 aaatgcgata ccaataggca aagagataga accaaagttt gataaataac caatagaaga
    16681 atgcatgctg atgattgatc cagcatttcc tagctcagcc aaccaaatat taaatgctcc
    16741 attttgcatc tgacctgcga tttctgccgt accaccaagg ggtgtgtaga agagtggcat
    16801 ccacaagaaa tgatgtaaac caagtggtaa tagcatacgg ttgaggaagc catagaagaa
    16861 gaatccaagt gaacctgctg ttgtagttgt tgcaacaact gactcaacaa ttccattgac
    16921 aactggccaa atatatgttg taacaatagc aagtaagata gtcaagaaaa tcagaataat
    16981 ataaactgac ttggttcctt catatggggc gagatactta tgtagcttaa tttcaccaaa
    17041 tttattaacc atgacaccaa cgaaacagcc tagcattata ccaaggaaca cacccatatc
    17101 gactacttgc ataccaaaga ccataccttg accagtacca tatagaccaa attctccagc
    17161 ttctgctagt cgatttgtca aggttagcca agagttattg gcatacaaga aaattaagaa
    17221 cgttacaatt cctagaatag ctgcgtcagt cttatatttt cgttttgcaa gagctgttgc
    17281 aattcctaca ctgaaaataa cacttagctg tccaatcata cccccagata ggatatcaaa
    17341 tataaaattc ccaatatttt tcgtgaattc tggcataaaa tctagtttta aaatagcaca
    17401 aatagataat acaattcctg ttacagccat aaacataacc ggctggatta ttgcctttga
    17461 aaagacactt gctgacttca tcattctttc tttcatgata aactcctctc gctaaaatgt
    17521 aatattgcca taatgatata actgaatatt gaaatcttta aataattgag caacatcttg
    17581 atcacacaaa agagaaactt ctttgacgcg tgctatgttg aaggaagaat taaagtagag
    17641 tatttcatcc acataagccg gatgtaccat taactccgta attgtattat cctcaatttg
    17701 atcaagaagc ttttcaactt ctgtcaaaca agctatttta tcactttcaa tgcttttcga
    17761 taaatcacga atgtgaggat agtttgttaa atcaaaaaat cctgttgctc caatttgatt
    17821 tggcagatcg atattaattt ctaaaccata tgcattgcgt aagggtaagc catatctctg
    17881 agctattctt tgactaatta acagattttc agggaaagta tgcaaatgat gatggctatc
    17941 aatatgggtt ggcttcaacc cttcatctaa taaatagtca atttgacaac accactcctg
    18001 atatatctct tcatcatcta tcttaaaccg attttcatga taatttttca aggaataaaa
    18061 tttcccttgt tgactaatag tcttaccttt agtcatagat tcaccacaag taagtaccat
    18121 atggacaccg acacccaaat cgggattttc ctttgctaac ataattgcct catcacagcc
    18181 aggcatatta gccattaagg ttgttgatgt caaaatacca tcctgaaatg ctttgataat
    18241 ccctgcattt acggctggtg aatagccaaa atcatcagca tttattatta cttttttcat
    18301 agaggtcctc ctttcactct agggctattg attgttgatt agtattttat catttacttc
    18361 acgcctagag tatagtataa tgaggaagtg aatacaatag cttttcaaaa gattgaaatc
    18421 gcttgcattt cttgaaaata ttttcaggag aaagagttat gtcacctatt tatcacccta
    18481 atcgcttgtt tcctaataat agtttttatc ctgaagatgg taaattgatt gaatcaatca
    18541 tcagaatgat tgaaacaggt gaaaatctcg atattcgtca tatcgctgaa ataaactata
    18601 cttctccatc ttcaattagt cgtttagcca agagagctgg ttttagtcat tttaaagaat
    18661 ttatcttttt tctgtcaacg acttcacaac aaaaaaacaa aagccaatta gctaatctcc
    18721 cctttgctag gacagactct gattgggaag ctattggaaa tcagcttaga catgcgttta
    18781 cagaaaagaa aattttttta tttggtgaag gtttctgtca atttctgg
//
