LOCUS       NZ_CP065054            22231 bp    DNA     circular CON 17-MAY-2024
DEFINITION  Streptococcus equi subsp. zooepidemicus strain SEZ13 chromosome,
            complete genome.
ACCESSION   NZ_CP065054
VERSION     NZ_CP065054.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Complete genomes of eight Streptococcus equi subsp. zooepidemicus
            strains isolated from mares in estrus with endometriti
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2021) Microbiology, Immunology, and Pathology,
            Colorado State University, 2025 Campus Delivery, Fort Collins, CO
            80523, USA
  REMARK    Annotation added by submitter
REFERENCE   3  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2020) Microbiology, Immunology, and Pathology,
            Colorado State University, 2025 Campus Delivery, Fort Collins, CO
            80523, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Coverage                   :: 246
            Sequencing Technology :: Illumina NextSeq;Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015689395.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 02:47:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,059
            CDSs (total)                      :: 1,970
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 16 of 37
            Pseudo Genes (incomplete)         :: 20 of 37
            Pseudo Genes (internal stop)      :: 16 of 37
            Pseudo Genes (multiple problems)  :: 14 of 37
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:11:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 811008
            Orig. end                         :: 833239
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065054.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22231
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="7"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     cand_cluster    1..22231
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22231
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12231](+)"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12231
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     gene            484..987
                     /db_xref="GeneID:83704592"
                     /locus_tag="I2432_RS03875"
                     /old_locus_tag="LJFMMFNO_00775"
     CDS             484..987
                     /codon_start=1
                     /db_xref="GeneID:83704592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678183.1"
                     /locus_tag="I2432_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00775"
                     /product="hypothetical protein"
                     /protein_id="WP_043029568.1"
                     /transl_table=11
                     /translation="MSTKVVSRLAIVSVCCFLLRLAFSGFLIAQPVMALLLIYLLYVNV
                     AEAILAMAGYVLLLACFFGFGPWIFWQMACYSMVLVLWRYFLNPLSDRLSQHRLINQVL
                     MAGVCAFCYHILLDSCFAYLYSISWWSYVWAGMLFTVTNALATMGYFLVVLLLLKRLSG
                     KKRP"
     gene            complement(1198..2391)
                     /db_xref="GeneID:83704593"
                     /locus_tag="I2432_RS03880"
                     /old_locus_tag="LJFMMFNO_00776"
     CDS             complement(1198..2391)
                     /codon_start=1
                     /db_xref="GeneID:83704593"
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679279.1"
                     /locus_tag="I2432_RS03880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00776"
                     /product="MFS transporter"
                     /protein_id="WP_206156327.1"
                     /transl_table=11
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAGE
                     LSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVVVM
                     YVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGSVLL
                     SFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFRESTF
                     ASFTILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVAPRIKV
                     SPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYSEYNHNK
                     LALIYTTNATLYAVFGVLFLLIPFVYSDIRIIGILINSLTIMIGFGLLIVHLQQERK"
     misc_feature    complement(2423..2439)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    complement(2751..2760)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.07"
                     /tool="antismash"
     misc_feature    2870..2879
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(2890..3393)
                     /db_xref="GeneID:83704594"
                     /locus_tag="I2432_RS03885"
                     /old_locus_tag="LJFMMFNO_00777"
     CDS             complement(2890..3393)
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /locus_tag="I2432_RS03885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00777"
                     /product="glutathione peroxidase"
                     /protein_id="WP_206156326.1"
                     /transl_table=11
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQAL
                     QELYDTYKEQGFEILDFPCNQFLHQAPGNATEINTFCSLTYHTTFPRFAKIKVNGKETE
                     PLFTWLKEQKSGPLGKRIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLFQEPI
                     DQSD"
     gene            complement(3386..5185)
                     /db_xref="GeneID:83704595"
                     /gene="pepF"
                     /locus_tag="I2432_RS03890"
                     /old_locus_tag="LJFMMFNO_00778"
     CDS             complement(3386..5185)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704595"
                     /gene="pepF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678180.1"
                     /locus_tag="I2432_RS03890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00778"
                     /product="oligoendopeptidase F"
                     /protein_id="WP_206156325.1"
                     /transl_table=11
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVSLFQRNY
                     EGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTKAS
                     VALSFFDTALANADLAVLDELEKNPYFSAAIRMAKIQKEHLLSPDVEKALTNLREVINA
                     PYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNGLRKH
                     QNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFGPVAQK
                     FLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTKEVERYQ
                     TERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQFIFSDNH
                     QSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYFHNFITHLL
                     EAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDATLTWMRQAHYYMGL
                     YSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIGADISTDKPLR
                     DTIQFLSDTVDQIIAYTEEIGHD"
     misc_feature    5293..5306
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.38"
                     /tool="antismash"
     gene            5383..8166
                     /db_xref="GeneID:83704596"
                     /gene="ppc"
                     /locus_tag="I2432_RS03895"
                     /old_locus_tag="LJFMMFNO_00779"
     CDS             5383..8166
                     /EC_number="4.1.1.31"
                     /GO_function="GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /GO_process="GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704596"
                     /gene="ppc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /locus_tag="I2432_RS03895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00779"
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="WP_206156324.1"
                     /transl_table=11
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEEI
                     IDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTNQD
                     YLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRRYRD
                     VKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAITALTS
                     KYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRFYIDKL
                     SALYQTFSLSSALIKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQTRLSQTLQELVG
                     QPASASLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQSLIAAGD
                     SSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENYSALSEEQK
                     CEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQHIISHTESV
                     SDMFELAIMLKEVGLIDQRQARVQIVPLFETIEDLDNARAIMTQYLSYDIVKSWIVTNA
                     GYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHGRGGTVGRGGGP
                     SYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISASINRMVTRMLTNP
                     DEIDGFRKIMDEIVEDSKRIYRELVFDNPHFYDYFFEASPIKEVSSLNIGSRPAARKTI
                     TDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAKLQHMYDKWPFFHSL
                     LSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKNVILAIAQHDELLEET
                     PSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHTTINGIATGLRNSG"
     misc_feature    8338..8353
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 26.13"
                     /tool="antismash"
     gene            8374..9654
                     /db_xref="GeneID:83704597"
                     /locus_tag="I2432_RS03900"
                     /old_locus_tag="LJFMMFNO_00780"
     CDS             8374..9654
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /locus_tag="I2432_RS03900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00780"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_012678178.1"
                     /transl_table=11
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPFR
                     SVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGAHG
                     WIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLRDWR
                     VYSLIMIVLVAAQPDLGNASIIVLTAIIMFSVSGIGYRWFSAILVLITGLSTAFLGMIA
                     VIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGLGNSIE
                     KRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNAMMALGV
                     GGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDANEKKEDIL
                     KEAELSYRKSVREENSNSKIININQFQ"
     misc_feature    9910..9925
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            10001..10861
                     /db_xref="GeneID:83704598"
                     /locus_tag="I2432_RS03905"
                     /old_locus_tag="LJFMMFNO_00781"
     CDS             10001..10861
                     /codon_start=1
                     /db_xref="GeneID:83704598"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375753.1"
                     /locus_tag="I2432_RS03905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00781"
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_021320592.1"
                     /sec_met_domain="TIGR01716 (E-value: 5.6e-50, bitscore:
                     166.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHFGKLFKKFRESRGLLLKDVAKAGISTSQLSRFENGETDLTIS
                     KFMSALDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMESEN
                     KREKFHQINTILLKIRLQELSGETCYSDHDLSYLTDYLFSVEYWGYYELLIFSNTLDVL
                     KHDVFMVLAREMSRRSDFYREIPNNRRLISTMLLNAYITCIGQGELIDALYFEKQLNQC
                     FFIETEVYERLVFQYAHHLYKYKKTGDCKAIIEMKKCIAAMTLAGSNHLAKTYEGHLKK
                     IIASK"
     gene            10912..11052
                     /db_xref="GeneID:83704599"
                     /locus_tag="I2432_RS03910"
                     /old_locus_tag="LJFMMFNO_00782"
     CDS             10912..11052
                     /codon_start=1
                     /db_xref="GeneID:83704599"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I2432_RS03910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LJFMMFNO_00782"
                     /product="hypothetical protein"
                     /protein_id="WP_154231861.1"
                     /transl_table=11
                     /translation="MDHQIKEEFIMQNDSQKESESLDLSINKIDLSSVILLYESSKSHG
                     H"
     gene            11125..12231
                     /db_xref="GeneID:83704600"
                     /locus_tag="I2432_RS03915"
                     /old_locus_tag="LJFMMFNO_00783"
     CDS             11125..12231
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704600"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649766.1"
                     /locus_tag="I2432_RS03915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00783"
                     /product="radical SAM protein"
                     /protein_id="WP_041790494.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.1e-43, bitscore:
                     146.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-19, bitscore: 68.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.3e-07, bitscore: 26.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.1e-08, bitscore: 29.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDERLWLTNWNKLYIKNKIDLKEAIMPLYIGFKITENCNQRCRHC
                     WASKNVMAHYTLDDIKAALGKIKQLNPYHVTITGGEPLVHDNWFEILQFAKDNFPVVEL
                     FTNGVLLNENNIRQLSELMEELDYIQISLDGLRESYNRQRGSDDFSTVIKNIKYIVQYG
                     INVRVNMTVTHYNIDEIMEVYELVRSLGVSSFSVSPVYPLRRGEKLVPLVDYNSYLSFG
                     EKLEKTHSELENDMNLTIIYPIEVQSKLAEYTKKNVINQFNTDLLHWTVDGKGDIFHFM
                     DQFPYKELRVGNIYENSLVELSKMDFQIQNKILSHSSKGLKCENCSLVASCPGLAYANS
                     FPELAFSYRRCIFNEKETYTRSITNSGE"
     gene            12185..13270
                     /db_xref="GeneID:83704601"
                     /locus_tag="I2432_RS03920"
                     /old_locus_tag="LJFMMFNO_00784"
     CDS             12185..13270
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704601"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649765.1"
                     /locus_tag="I2432_RS03920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00784"
                     /product="radical SAM protein"
                     /protein_id="WP_012678175.1"
                     /sec_met_domain="PTHR43273 (E-value: 6.7e-34, bitscore:
                     114.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.8e-14, bitscore:
                     48.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.3e-08, bitscore: 30.8,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKHILEVSQTLGSDFDLPYYIYSKIKRNKTEKVISPLKIGLKI
                     TNACYFRCPYCFVSKEEDYLLFDHLKIIIDKLPQLPFEVYLTGGEATLHPEFPKIVDYL
                     VDLGILVKLHTTGVITEKSRNYIISNLEKFSSIQISIDSIKNFDKLRPSHIVINPLEQI
                     CSFVQKCLDRDYKKLLVNIVISSLNIHELDEVIDFCFKQGLLRIQLSSIFSIHNRLLVS
                     DEKYAAHYNKLIEKFSCLGVQFLTSPFCHPWSLAIKHGIEYHSPLYCPAQKTEFEIDMY
                     GDVYPCPFLHDKIHLMGNLISDDFETIWYSGVEQLNRRAWSSNDSCKNCKLFNDCGGGC
                     YAMAFVSQLEYDKRCILHANQ"
     gene            13257..13517
                     /db_xref="GeneID:83704602"
                     /locus_tag="I2432_RS03925"
                     /old_locus_tag="LJFMMFNO_00785"
     CDS             13257..13517
                     /codon_start=1
                     /db_xref="GeneID:83704602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649764.1"
                     /locus_tag="I2432_RS03925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00785"
                     /product="hypothetical protein"
                     /protein_id="WP_012678174.1"
                     /transl_table=11
                     /translation="MQISKNWFIRFEPNFQTTQNTILFNKVSGELFEVTEVYYDCINSL
                     RIGVDFQALLMEKYAVNAGDVIDVEDTILKNLISLGVILNE"
     gene            13510..14409
                     /db_xref="GeneID:83704603"
                     /locus_tag="I2432_RS03930"
                     /old_locus_tag="LJFMMFNO_00786"
     CDS             13510..14409
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704603"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /locus_tag="I2432_RS03930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00786"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_021320595.1"
                     /transl_table=11
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKSTL
                     IKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHLNN
                     LSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEPTNG
                     LDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSFSEIF
                     GENNTWMKYRIGIPKFEKASFDQLFPFLAYQVEDERLVVEVTDSQTKHHIFEHFEIIFF
                     EEVEKSIEELLYEVITDD"
     gene            14399..15139
                     /db_xref="GeneID:83704604"
                     /locus_tag="I2432_RS03935"
                     /old_locus_tag="LJFMMFNO_00787"
     CDS             14399..15139
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /locus_tag="I2432_RS03935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00787"
                     /product="ABC transporter permease"
                     /protein_id="WP_111690554.1"
                     /transl_table=11
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFEDT
                     QSQFLLLCLLFTWYFTSHSITHPTFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQLL
                     VDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVFNRT
                     SSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAYGVIY
                     WSVGTLLFSRALTMAKKRGSLFHV"
     gene            15132..15710
                     /db_xref="GeneID:83704605"
                     /locus_tag="I2432_RS03940"
                     /old_locus_tag="LJFMMFNO_00788"
     CDS             15132..15710
                     /codon_start=1
                     /db_xref="GeneID:83704605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678171.1"
                     /locus_tag="I2432_RS03940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00788"
                     /product="hypothetical protein"
                     /protein_id="WP_154298852.1"
                     /transl_table=11
                     /translation="MFSEMKRYMTYRVRYLFNSICDVIYSFIFITGIIVIVDSKAPINI
                     LYFFTYYLITNVILLANEELEYEIRTNQYMNIKTTKQTPLMIYIYRSGTYFIWSALIFL
                     MSISLAQIFFKGKWLFPTLTVLEVILMLMVNGVVALVLYILAIKLTERFKRVSVFLHLM
                     NTLMLFYSGLVFPVPFFTYANVLDFIVGI"
     misc_feature    15790..15805
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.44"
                     /tool="antismash"
     gene            15982..17538
                     /db_xref="GeneID:83704606"
                     /locus_tag="I2432_RS03945"
                     /old_locus_tag="LJFMMFNO_00789"
     CDS             15982..17538
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704606"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622671.1"
                     /locus_tag="I2432_RS03945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00789"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_206156323.1"
                     /transl_table=11
                     /translation="MKKLLSYLGRFRYFALLVFMLGGFSSILQSLVIQRVIAIDTVSDF
                     RSLWKLFIVGLLTYLLFYGLEFGANVVYDVACKRIMLALRDKLTRKLLLSGQAIDQHEA
                     TNFLSQDLEFFYDNYVTQVMRLPKDGMIFLVVAIYLITLNPLLAFLFIVGSLLRPLPQL
                     FLTQTTESLGKRQSDERERSMSLIMDYVNGSSTLLHHQAFESTYDQLANQVLTYETARR
                     NYYYLSNFLFFCNGLTQFLGRVVPIGLYFLLPMVFGHIPVSSLIAMFMASNHLANPLQN
                     MMYATFSMQAAVSVKAKIDDMMDQVADEAETPYVPYFKALALEGITKSYGAKLILKDFS
                     YTFEQGKKYLIKGASGRGKSTLLHIIKGAAVDSGKIAFITKDKQSFENYQANVGMVNQA
                     PFLFNGTLEENVCLNQEFSKEDILAVLDQVHLLEELPAGLGFQIENNGTNISGGQRVRI
                     ELARFLLRQKDILLLDEVTAALDKDNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIE
                     L"
     gene            17548..19110
                     /db_xref="GeneID:83704607"
                     /locus_tag="I2432_RS03950"
                     /old_locus_tag="LJFMMFNO_00790"
     CDS             17548..19110
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704607"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /locus_tag="I2432_RS03950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00790"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_043052932.1"
                     /transl_table=11
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTSLNNHQD
                     TLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNHREMSHDKKIS
                     MLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQHVI
                     GQKAEQKGSELAVARQKLLGLLSDVVAGRSTLTQNQALFASLKQVKKQSEHYESSRQGF
                     EIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQPLKNIV
                     DDIFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRTLFSDLS
                     FHFEKGKKYLIKGPSGSGKSTLFKLILQEMSPDEGTLDMVLAGGQTTDNYHHRIGLIAQ
                     SPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNYQIVNNGENISGGQKTR
                     LEIARSLIRQKDVLLADEVTAPLDVNNAKTIRQLLFSLPVTVIEIAHHIDDTFIYDGDI
                     DLS"
     misc_feature    complement(19314..19329)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            19493..20594
                     /db_xref="GeneID:83704608"
                     /gene="prfB"
                     /locus_tag="I2432_RS03955"
                     /old_locus_tag="LJFMMFNO_00791"
     CDS             join(19493..19564,19566..20594)
                     /codon_start=1
                     /db_xref="GeneID:83704608"
                     /gene="prfB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /locus_tag="I2432_RS03955"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="LJFMMFNO_00791"
                     /product="peptide chain release factor 2"
                     /protein_id="WP_115266987.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPDF
                     WNDNMAAQKTSQELNELKLTYQTFHNMQELSDETELYLEMLDEDDSVKEELEASLTRLS
                     QMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKVETL
                     DYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVEVMPE
                     LDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRTQYGNR
                     DRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDHRTNFEV
                     AQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            20645..21337
                     /db_xref="GeneID:83704609"
                     /gene="ftsE"
                     /locus_tag="I2432_RS03960"
                     /old_locus_tag="LJFMMFNO_00792"
     CDS             20645..21337
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704609"
                     /gene="ftsE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /locus_tag="I2432_RS03960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00792"
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="WP_012678167.1"
                     /transl_table=11
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKST
                     FIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENVAY
                     AMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKLLIA
                     DEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIVRDEE
                     KGDYGYDD"
ORIGIN
        1 aatattagat gctaaaaggt catagtcaat gtcacttggc agctgccatc cagaaacatc
       61 aataatgggg tttagtagaa attcagtagt ttcagatgtg cttgtagtcg acttattgga
      121 cgtgctagtg ttagtgggaa tgcttgcctt ggcaagcttt agctctttac ttttgagatt
      181 atcagaatga gcctttccaa tgattaacaa agtagcaatc agcgtaaaga agaccacaac
      241 aacaataggt tttattcttc ttctcatcag tcttattgta ccttaaatgc ctcaaaaaat
      301 caaagtggtc ttacgatttt cttaggtttt tagcctgtta ggacagcttt ggcagatcat
      361 gtcctatcta ttttcgtttg attttagtct atctgtcttg taatcatcta tcaaaaagct
      421 gttgaggctg gtcaagaggt gtaaaatctg tcataataga taaaaaacac tcaaagaggg
      481 attatgtcta ccaaagttgt tagtcgacta gctatcgttt ctgtatgttg tttcttgcta
      541 cgcttagcct ttagcggctt tctcattgcc cagccagtca tggctctttt attgatttac
      601 ctgctctatg ttaatgtagc agaggctatt ttagcaatgg cgggctatgt gctcttgtta
      661 gcttgctttt ttggttttgg tccttggatc ttttggcaaa tggcttgtta ttcaatggta
      721 ttggttttgt ggaggtattt cttgaatccc ttatcagaca ggctatcgca gcacagattg
      781 atcaatcaag tcttaatggc aggagtctgc gccttttgct atcatatact gctagatagt
      841 tgctttgctt acctttatag tatctcttgg tggagttatg tatgggcagg aatgcttttt
      901 acggtgacta atgccttagc cactatgggt tatttcttgg tagtgctttt attgcttaaa
      961 aggctatctg gtaaaaaaag accttaagct gtccgcttag ggtcttgatg ctggctttga
     1021 cgtcataact agtagtagcg cagttgctgt cgatcaatca tttctttttt ttgttttttg
     1081 aatcctctta tgttgatgga tagtttttga ttatttaata ttgagttctg gtttcttttg
     1141 gtaaggaagc ttattttgtt gaagagcttt atccattttg ctggttttag aactaagcta
     1201 ttttctttct tgctgtaaat ggacgatgag taatccaaag cctatcatta ttgtcagact
     1261 attgatcagg attcctataa tccttatgtc gctataaaca aagggaatca gtaaaaatag
     1321 gacaccaaaa acagcgtata aggttgcatt ggtcgtgtag atcaaggcga gcttgttgtg
     1381 gttatactca ctataaatca ttttttcaaa tacattgccc gatatgccaa taatcgtgaa
     1441 ggtaatgaaa aacaaaagta attttaccat cggataggga atcataaagc aaagcaagaa
     1501 gctgcttcca gacaggatat aatcaatgaa aaagaagctt cgtggagata ccttaatgcg
     1561 aggcgcaact agagccccta ataaatctgc tgctctgtga gctgctaaaa caaggccaat
     1621 gtattcgatt gaaatgccct cagacagtag atacaaggga aggagtgcta gtaataaatc
     1681 ggttcctccg ctgagaaagg cttctaccaa gatggtaaag gaagcaaagg tcgactctct
     1741 aaatgcacgt agtgattctg ttacagaagc aggtttttca atctcgtcat tagtcgtggt
     1801 actaagctta gacgggctaa gctgaatcct aaaaataaaa gctatggctc ctataaagaa
     1861 aggcaggctc aattgcagta aaacgagata ggaaacaaag ctaagaagaa cagagcccac
     1921 aaaattgcta acaatatcta gaacgtttga tgtagcgtat tgaatatcta ctgatttttc
     1981 aatgaggtct gaatcatcgt ctagtgttct gggaacgatt ttcatttgaa tggtatttaa
     2041 tacggttgtg accaagttaa aggcaaggtt gagcacatac atgacaacaa ccggtagctg
     2101 atagcttaag cagatgataa tactgatgat gacaatgagc tgtatcatct gaaagacaat
     2161 taaccatttt ttatcatttt ttaagttatg gattaaagaa ccgtaagcaa aagacagcat
     2221 atttggcaat aaaccaacca atgtcaaaaa agaaagttct cccgcgttaa tgttgtaaac
     2281 cttaagtaaa ccaacagaca aagcaatcat gtaaaaactg tctgcgatat tgcgacttga
     2341 cctactaaaa ataaggttat agaagttact tgttaaccct tgaaatctca tgctgataaa
     2401 ctctccaatc agtacaatct atttgaatgt catttgaaac tcctgaggtc atttgcatgc
     2461 tgtccactgt gataggatta agggtaaggg cttttggcag cacagcttag atcattcaat
     2521 agtcatgtgt ttttcttaat tttataagat gattttaatg atcctaatca catgcgtcaa
     2581 tgctttttac tgttgatgac tgaagtaaat gtccttaaat catgtgaacc ggtacttttt
     2641 gataaacata aaaaggctag cataagttat cattgctcaa gtgcaccagt ccttacagga
     2701 agcagcttga atgatttgat tgaaaaaagt aagcttaggt gtgaggacaa ggtccccttc
     2761 aaaaaagttc tttgaagaat agacaagcaa atagctgacc tttagcagct ccttggcaaa
     2821 gcaagaagct ttagatataa aaataagcca agaaataagg atcttggctt gttttttgat
     2881 aggacttcgt tagtctgatt ggtcaattgg ctcttggaaa agcaattgct gtagggcttt
     2941 ttcaatcatt ttggggtctg tttttgaggc atagcgctca acaacctgcc ccttttgatc
     3001 aattaaaaat tttgcgaagt tccattcgat gcgcttgccg agtgggccac ttttttgttc
     3061 tttgagccaa gtgaataatg gctctgtctc cttgccatta accttgattt tggcaaagcg
     3121 tggaaaggtg gtgtggtaag ttaagctgca aaaggtattg atttctgtag cattacccgg
     3181 tgcttgatgt aaaaattgat tgcaggggaa atcaaggatt tcaaagcctt gttccttgta
     3241 ggtgtcataa agctcttgta atgcttgata ttgaggagtt aatccgcatt tagtggcggt
     3301 gttgaccact aataggacct ttccttggta ttgctccagt gaacaatcag tgccatcttg
     3361 tcttttaacg ctaaagtcat aaatgctagt catgaccaat ttcctctgta taggcaatga
     3421 tctgatcaac cgtatcgctc aagaattgaa tggtatcgcg aagcggcttg tctgttgaga
     3481 tgtcagctcc gatgagtagg gctgtctcaa gcggggtacg actgccacca gactttaaga
     3541 aatcaagcca ttcgttggca ccatttgggt tattctttag attgaggtag ccggcagtcg
     3601 aaatcacaag ccctgcagaa taagtatagc tataaagccc catgtaataa tgagcctgcc
     3661 tcatccaggt aagggtagcg tcatcatcaa tctcaacagc atcaccccag aactctgtta
     3721 aaacatcctt catcatggca ttaagctgct ctgcaccaaa ggtgcccccc tcttcgatga
     3781 gggtataaac cttacgctga aaagcagcct ctaacaaatg cgtgatgaag ttgtggaaat
     3841 aagtatctgt caggcggtgc gccagtgcaa agcgtttttg acgaggcgtg tcaaattgtg
     3901 cctccaaata atcactcagc attagctcat taaaggttga tggcgcttca acgtaatagg
     3961 ttgacatgtg tgtgttgaag tagctttggt gattgtcaga gaagataaac tgaccagaat
     4021 ggccaatctc atggatcagc gtgtaaacgt cagacatacg gcctgtccag ctcatcagca
     4081 cataagggtg aaccttgtaa gggtcagcag cgtagccacc agaatcctta ttggcatttg
     4141 cagcaaagtc cacccagcgc tctgtttggt agcgttcaac ttctttcgta taggctggac
     4201 caagtggtgc taatgatgcc atcaccaagt cataagcccc atcaatagag acctctggat
     4261 tgagggcatt atcaatatct agcttccagt ctgcaaaagt catcttgtct aagccattta
     4321 cccttgccac atgctttaag aatttttgag caactggacc aaattcggtc atgatgaggt
     4381 cgatttgacg gtcaaacatg ctgcggtcca cctcctgctc agccagcagg taatcaaaaa
     4441 cagacgcata gcccttcata tcagctaaga gcttttctga tttgacctta gcaagatagg
     4501 ctgcggctgc tgcattttgg tgcttacgca gtccgtttga gaaggaacga aaggccttgt
     4561 cacgaatggc agcattttca tggttttgat aaaagttttc ataggaaaca aagctatttt
     4621 tgtagacttt accatcaact tcaaaatcct ccatctcaaa atctccagcc cgcattttgg
     4681 tgtaaatgtc gtaaggagcg ttgatcactt ctcgtagatt ggtcagtgcc ttttcaacat
     4741 cagggcttag caaatgctct ttttggattt tcgccatgcg gatagctgcg ctgaaatagg
     4801 gatttttttc caattcatca agaacagcaa ggtctgcatt agctagggct gtatcaaaga
     4861 agctgagggc tacgctagcc ttggtcatga agtcatcacc agcctgggca atttgagcaa
     4921 atgcttcatc tgaaaaatca gtggtctgtg gcataaaggc ataggtgcta atatgactca
     4981 tttgaatata aatctgctca atctccatca aggcctgtgt aaaatcctga gcagttgtta
     5041 atttgccttc gtaattgcgt tggaataggc tgacatcttg taaggctttt tcaatagcca
     5101 atagaaaatc ttccctgtct ttgtagaggg cagttaggtc ccaaagctca ttttcaggga
     5161 attctgaacg tttttttaat tccataatgt tctccttcat gagtaattac ctatagtata
     5221 acaaaaatta gaagcgatag cctgtaaaag ctttacaaac atttttgtac caatgaatct
     5281 tatatgtcaa ggaaaacaaa cattcctagc caataggctt acatttttag caaaaagtgg
     5341 tatgatagga gggaaactag cataagaagg gaagtccgtc atttgtcagt caaaaaatta
     5401 gagagctata ataatcagga gattattgct gaagaggttg ctatcctaaa ggaaatactt
     5461 gagagcatta cgcgtcgcat gattggtgat gaggcctttg caaggattga ggaaattata
     5521 gacctatctg aaaaacagga ttatgtgctt ctagagcaat tgatcgctaa gattagcaat
     5581 aaagatatgg aatttatttc acgatatttt tcgattcttc cgctgttgat taatatttca
     5641 gaggacgttg atttggctta tgaaatcaat cgtcaaaaca atacaaatca agactatctg
     5701 ggaaagcttg ctctgaccat tgcttctgct gctgaaaagg aaaatgccaa ggaactgttg
     5761 gaaagggtga cggtggttcc agtcttgaca gctcacccaa cacaggttca gcgaaagaca
     5821 gttctagagt tgaccaatag cattcataac cttcttcgtc gctatcgtga tgtcaaggcg
     5881 ggtgtcatga atcaaaacaa atggtatagt gagctgtacc gttacattga tattctcatg
     5941 cagacggata tcattcgtga gaaaaagctc aaggtcaaaa atgagattac caatgtcatg
     6001 cagtattaca atagctctct gatacaggcg atcacagcgc taacaagcaa gtataagacg
     6061 ctggccaagg acaaggggat cttgctggac aatccaaagc cgattaacat gggcatgtgg
     6121 atcggaggag accgagatgg caatcctttt gtcacagcag agacactgag gctgtctgca
     6181 acagttcaaa gtgaggttat tctgcgcttt tacattgaca aattgtcagc tctttatcaa
     6241 accttttcgc tgtcatcagc tttgataaag accagtcctg aggtggaacg cttggctagc
     6301 ctatccagtg atcagtccat ttatcgtgag aatgagccct accgcagagc ttttcactat
     6361 attcagactc gtctaagcca aaccctgcag gagctagtgg gtcagccagc ctcagctagt
     6421 ctagcatcta gaatgcctgc tacggtaggc tcgcttcagt cgggcgttac aagcattgtg
     6481 accaatagca gtgaccagca agcaccagcc tataagacag cagcagcttt taaggctgat
     6541 ctggtcatga ttgagcaatc tctcattgca gctggggatt cctccttggt tgagggggat
     6601 ttgcaagagg tcctacaagc ggttgatatt tttggtttct ttttggccag tattgatctg
     6661 cggcaggatt ctagtgtgca ggaggcctgt gttgctgagc ttttgaaaaa tgctggtatt
     6721 gttgagaatt acagtgcttt gtcagaggag caaaaatgtg aggtcctctt aaaggagctg
     6781 acagaagacc ctcgcaccct ctcatcggca gctgttgaaa agtcagagct gttagaaaag
     6841 gagcttgcta tctatacagc ggcacgtgag ctcaaggata agcttggtga agaggtgatt
     6901 aaacagcaca tcatttcaca tacagagagt gtttctgata tgtttgagct ggctatcatg
     6961 ctaaaggagg ttggtctcat tgaccaacgt caggcgcgcg tgcagattgt gcctttattt
     7021 gaaacgattg aggatttgga taatgctaga gcgatcatga cacaatacct tagctatgat
     7081 attgtcaagt cttggattgt tacaaatgct ggctatcaag agattatgct tgggtattca
     7141 gatagcaaca aagacggtgg ctatttggcg tctggctgga cactttacaa ggcgcaaaat
     7201 gagctgacca aaattgggga ggacaatggt atcagcatca ccttctttca tggacgtggt
     7261 gggactgttg gacgtggtgg cggtccatcc tatgaggcga tcacctcaca gccatttggc
     7321 tctattaaag accgaatccg cttgacggaa cagggtgaga ttattgaaaa caaatatggc
     7381 aatcaagatg tggcttacta caacttggaa atgctgattt ctgcttctat caatcgcatg
     7441 gtgactcgca tgctgacaaa tcccgatgag attgatggct ttaggaaaat catggacgaa
     7501 attgttgaag acagtaagcg tatttatcga gagctggttt ttgacaatcc gcatttctat
     7561 gactatttct ttgaagccag tccgattaag gaggtatcaa gcttaaacat tggttctcgc
     7621 cctgctgctc gtaaaaccat tacagacatc tcaggcctgc gtgccattcc ttgggtattt
     7681 tcttggtcac aaaaccggat catgcttcca ggctggtatg cagtaggctc tgcctttaag
     7741 cgttttattg ataaagaaga gggaaattta gccaaattac agcatatgta tgacaaatgg
     7801 ccattctttc attccttgct gtctaatgtt gatatggtat tatcaaaatc aaacatgaac
     7861 attgcctttc aatatgcgca gttagcagaa agcaaggagg tctgtgaggt ctttcatacc
     7921 attcttgatg agtggcagct gactaagaac gttattcttg ctatcgcaca gcatgatgag
     7981 ctgcttgagg aaaccccatc cttgaagcaa agcttggatt tccgcctccc atattttaat
     8041 gtgttaaact acattcagat tgagctgatt aagcgtcttc gtcatgagca gctagatgag
     8101 gactatgaaa agctgatcca cacaactatt aatggtattg ctacaggact tcgtaattcc
     8161 ggctaagccg ttgaagatca atcagcagct cacacagaca ggctactagg ttataatggc
     8221 ttgtctgtgt tttttagatt gagcgattcc aaggatacag caagctttgt ctagagccat
     8281 gcttggctag gtgcttgcaa tgtatttttc ctttgtttta ccaatgaaag atgatataat
     8341 gctaatgatt atctcaagat tataggggaa atgatgaaaa ttgataaaag gcatttgcta
     8401 aattactcca tattactacc ttatctgatt ttatctgtga ttgggctgat catggtttat
     8461 tccacaacca gtgttagctt gattcaggct caggccaatc catttcggtc agttgccaat
     8521 caagggctct tttgggttgt cagcttagtt gctattacct ttatttacaa gctaaagctg
     8581 aattttttga ccaataccaa ggttttaaca attgttatgc tgcttgaaat cctgctattg
     8641 attgctgctc gcttttttac gacagcgatt aatggcgcgc atggctggat tgtccttgga
     8701 cctctgaggt ttcagccagc agagtatctg aagattatca tggtttggta cctagcactc
     8761 accttttcaa agatgcagga aaagattcat cagtatgatt atcaggcctt gacgcgtcgc
     8821 aaatggtggc caacagaatg gggtgacctg cgtgattggc gtgtttattc cttgattatg
     8881 attgtgctgg ttgctgcgca gcctgatttg ggcaatgcct ctattatcgt gttgacagct
     8941 attatcatgt tttcggtcag tggtataggc taccgttggt tttctgccat tttagtgcta
     9001 attactggtt tgtcaactgc ttttttggga atgattgctg tcattggtgt tgaaaaggtg
     9061 gctaagattc cagtttttgg ttacgttgcc aagcgcttta gtgctttttt caatcctttt
     9121 cgtgatttga cagattcggg acatcagctg gctaattctt attacgccat gagcaatggt
     9181 ggctggtttg gcagagggct tggaaattcg attgaaaaac gaggctatct tccagaggca
     9241 cagacagatt ttgtcttttc tgtcgtgatt gaggagttag gactgattgg tgcaggattg
     9301 atccttgcgc ttgttttctt tcttattttg agaatcatga atgtcgggat taaggctaaa
     9361 aatcccttta acgccatgat ggctcttggt gttggtggca tgatgctgat gcaggtattt
     9421 gttaacattg gtggcatttc tggcctcatt ccttcaacag gggttacctt tccattctta
     9481 tcacagggag gaaacagcct gctggtcttg tctgtagggg ttggctttgt cctcaatatt
     9541 gatgccaatg agaagaaaga ggatatttta aaagaagcag agctatccta ccggaagtcc
     9601 gtccgagagg aaaacagtaa tagtaagatt attaatatta atcaatttca gtaaagaagc
     9661 tccttgtcaa ctgtggcggg tggcttataa caaacattta gagaggacca ggtgggtctt
     9721 ttctttttgt catcatagca cgaagttaaa taaaagaaaa gtcagcatct ttaagtgctg
     9781 acggatagtg taggcttatg attctagtac aaaccactcg ttaggcaaat ggttataagt
     9841 agcctacaac gatgacaata atttcttcta ataccatcaa aagaagcatt aaaaaatgac
     9901 gtttgttcat gtgataatcc tcacttctgt ttttctatag tgtatgttat gatagaacta
     9961 atgataagtc tttcccgtat gtacaagtga ggtggtagtt ttgaaacatt ttggaaaact
    10021 ttttaagaaa tttagagaat ctcgtgggtt gctcttgaaa gatgtcgcaa aggctggtat
    10081 atcaacatct cagttgtcac gttttgaaaa tggagagact gatttaacga tttctaagtt
    10141 tatgagtgcc ttagatgaga ttaatatgcc tattgatgaa ttcatgtatg cggtacatga
    10201 ttttcatcgc gatgagttaa acgaactgtt gtctaaagtc cgtcattttg tgtctactcg
    10261 cgatgtagaa ggcatgaaaa aacttctata ttctcagatg gagtcggaga ataagcgcga
    10321 gaaatttcat caaatcaaca cgattttgtt aaaaattcgc ttgcaagagt tatcagggga
    10381 aacctgttat tctgatcatg atctatctta tttgactgat tatcttttta gtgttgaata
    10441 ctggggttac tatgagctct tgattttttc caatacatta gatgttctaa agcatgatgt
    10501 atttatggtt ttggctagag aaatgtctag gcggtctgac ttttatagag aaataccaaa
    10561 taatagacgg ctcatttcaa cgatgttgtt aaatgcttat atcacatgta ttggacaagg
    10621 agagctaatt gatgccttgt attttgaaaa acagttaaac caatgctttt tcatcgaaac
    10681 agaggtttat gaacgtctgg ttttccaata tgctcatcat ctttacaaat acaaaaaaac
    10741 tggagattgt aaggctatta ttgaaatgaa aaagtgtatt gccgcaatga cattggctgg
    10801 aagtaaccat ttagcaaaga cttatgaggg acacttgaaa aaaatcatag caagcaagta
    10861 gcaagtgcag atatgggaat agtgttcaat aattatttca gaagggtata attggatcat
    10921 caaattaagg aggaatttat catgcaaaat gatagtcaaa aggaatcaga atcacttgac
    10981 ttatcaatta ataaaattga tttgtcatct gttattctac tttatgagag ttcaaaatct
    11041 catgggcact aattaatgat taaggggggg agttttttcc tccttaattt tataaatttg
    11101 tattaataat aaaggaatta gtaaatggac gaacgccttt ggttaactaa ctggaataag
    11161 ttatatataa aaaacaaaat tgatttaaag gaggctataa tgcctctcta tataggattc
    11221 aaaattacgg aaaattgtaa tcaaagatgc agacactgct gggctagtaa aaatgtgatg
    11281 gcacattata cacttgatga cattaaagct gcattaggaa aaatcaaaca attaaaccct
    11341 tatcacgtta caattacagg cggagaacca ttggtacatg acaattggtt cgaaatttta
    11401 caatttgcta aagataactt tccagttgtt gaattgttca ctaacggtgt acttttgaat
    11461 gagaataaca ttaggcaact gtctgaactt atggaagaat tagactatat tcaaataagt
    11521 cttgatggat tacgagagag ctataatagg caacgaggct cggatgattt tagtacagta
    11581 attaaaaata ttaaatatat tgttcaatac ggtattaatg ttcgagttaa tatgacggtt
    11641 acacactata atattgatga gataatggag gtttatgaac ttgttagaag ccttggagta
    11701 tcttcatttt cagtatctcc tgtgtatcct ttaagaagag gagaaaaatt agtaccttta
    11761 gtagattata acagttatct atcttttgga gaaaaattgg aaaaaactca ctcagaactt
    11821 gagaacgata tgaatttgac gataatctat cctatcgagg ttcaatcaaa gttggcagaa
    11881 tatactaaga agaatgttat taatcaattt aacacagatt tattacattg gactgttgat
    11941 gggaaagggg atattttcca ttttatggat caatttccat ataaagaatt aagagttggg
    12001 aatatatacg aaaattcctt ggtggaactc tccaaaatgg attttcaaat tcaaaataaa
    12061 atactatcac attccagtaa aggcttgaaa tgtgaaaatt gtagtttagt agcatcttgt
    12121 cctggccttg cctatgctaa ttcttttcca gaattagcat ttagttatag aaggtgtatt
    12181 tttaatgaga aagaaacata tactagaagt atcacaaact ctggggagtg attttgattt
    12241 accttattat atatattcca aaataaaaag aaataagacg gaaaaagtta tatctcctct
    12301 taaaattggt ttgaaaatta ccaatgcatg ctattttaga tgtccgtact gttttgtatc
    12361 aaaagaagaa gattacctct tgtttgatca tttgaaaata ataatagata aactacctca
    12421 acttccgttt gaagtttatc taactggtgg tgaagctact ttacatcctg agtttcctaa
    12481 aattgtggat tatcttgttg atctaggaat tcttgtaaaa cttcatacaa ctggggtaat
    12541 tactgaaaaa agtagaaatt atattatttc taatttagaa aaattttctt caatacaaat
    12601 aagcattgat tctatcaaga attttgataa acttagacca agtcatattg ttatcaatcc
    12661 tttggaacaa atatgttctt ttgtgcagaa atgtttagat agagactata aaaaattgtt
    12721 agtgaatatt gttattagct cgttaaatat ccatgagctt gatgaggtca tagatttttg
    12781 ttttaaacaa ggattgttac gtatccaatt atcttctatt ttttctattc ataatagatt
    12841 attagtatct gatgaaaaat atgctgcaca ttataataaa ttgatagaga aatttagttg
    12901 tttaggtgtt caatttttaa catcaccttt ttgtcaccca tggtctcttg caataaagca
    12961 tggaattgaa tatcattccc cactttactg tccagctcaa aaaacggaat ttgagattga
    13021 tatgtatgga gatgtctatc cttgtccatt cttacacgat aaaattcact taatgggaaa
    13081 tttaatttct gatgattttg aaactatttg gtactctgga gtagaacagt taaatagaag
    13141 ggcttggtca agtaatgata gttgtaaaaa ttgtaaatta tttaatgatt gcggtggagg
    13201 gtgctatgcc atggcatttg tttcacagct agaatatgat aagaggtgta tattacatgc
    13261 aaatcagtaa aaattggttt attagatttg aacctaattt tcaaacgaca caaaatacga
    13321 tattatttaa taaagtaagc ggagagctgt ttgaggtaac agaagtttac tatgattgta
    13381 tcaattctct gagaattggt gtcgattttc aagctcttct gatggaaaag tatgctgtca
    13441 acgcagggga cgtgattgac gtagaagata cgattttaaa aaatctaata tcgctaggag
    13501 taattcttaa tgagtgacat cactatacgc catgtcaaga aaagctttca tcatcaggta
    13561 gtcttagatg tgcctagttt tgatgtaaag cgtggagaaa ttgttgctat cgttggtgca
    13621 aatggtgcag gtaaatcaac tttgatcaaa atgatctctg gtttaatgct gcaagacaca
    13681 ggatctgttt tggtttatca tcataaaaat acttcagcag ctattcatcg tgatgtgaaa
    13741 tttgtcttag aaagtggtag gggctattac gagtatctga ctgcaaatca aaatattgat
    13801 tactttttac atttgaataa cctgtcacgc agccaagtca aagaagaatt ggcagagttg
    13861 tgccaaaaat tggcttttaa tccctatact gatcggttgg tttctgaatt atcccaaggc
    13921 acaagacaaa aattgtcttt gattattgct cttctttgtc agcccaaggt tctgtgctta
    13981 gatgagccaa caaatggtct agatgtggtt gcaaaaaagc aatttgcaac cttgttgctt
    14041 gagcttagtc aaaaaaagca aacgattatc ctgatgacga ctcatgatat cttttttgta
    14101 aaagagctat cagcaagaat ttgtgtcatg agtaaaggga agatcaaaaa acaggggagt
    14161 ttttcagaaa ttttcggaga aaacaacacg tggatgaaat atagaatcgg tatccctaag
    14221 tttgagaagg ctagttttga tcagttattt cctttcttag cttatcaggt agaagatgag
    14281 agattagtcg tcgaagtgac agatagtcag acaaaacatc atatctttga gcattttgag
    14341 attatatttt ttgaagaggt tgaaaaaagc atcgaagaac tattatatga ggttattact
    14401 gatgattaaa gaaatacaaa gggagttgaa aagacaattg caggagatga tgcaattcaa
    14461 attcaattta ttttttgcaa actttggtat tttgatcatg gtgtcatctt atcttcacta
    14521 ttttgaagat acgcaaagtc agttcttgtt attatgtcta ttattcactt ggtattttac
    14581 gagtcatagc atcacacatc caaccttttt tattgaggat gacctttatg atagaacgtt
    14641 gatcagtgtt attcaaagca gcaagagtgt ttttcatgtc ctcatgctta aaattattgt
    14701 tcaactattg gtggatttag ttaaggcaat acctattgtt atcatgttat cactccttaa
    14761 taatattgac tttccagaaa gtagcttgag ggtgatggga agctttgttg cctgtttttt
    14821 gacagtcatt agtacatacg gtcttggctt ttgcttatcc agtctctgtt ttgtgtttaa
    14881 tcgtacctcc agtgttactg cgttaatttc ttatttcatg ctatacttta ccggcatact
    14941 aacgccatta gatggctcac ttggtcttat tggaaaaatg ttcccttatt atgctttgag
    15001 aaatgctatt atgtcccctt catatcaaag cgtatgttgg attgtggctt acggtgtgat
    15061 atattggtcg gtcggtacgt tattgttttc tagggcattg acaatggcta aaaaaagagg
    15121 gagtcttttt catgtttagt gaaatgaaac gatatatgac ttatagggtg cgctatttat
    15181 ttaatagtat ttgtgatgtg atctattctt ttatttttat taccggcatt attgtgatcg
    15241 ttgatagtaa agcaccgatc aatatcttgt atttctttac atactatttg atcactaatg
    15301 tgattttgct agctaatgaa gagctagagt atgaaattcg taccaatcaa tacatgaata
    15361 tcaaaacaac aaaacagacg cccttgatga tttatatcta tcgatcagga acctatttta
    15421 tctggtcagc acttattttt ctgatgtcaa tcagtttagc gcaaattttt ttcaagggta
    15481 aatggctgtt tcccacattg actgtattgg aagtgatttt aatgttaatg gttaatggtg
    15541 ttgtagcctt ggttttgtat attttggcga ttaaactaac agaacgtttt aaaagggttt
    15601 ctgttttctt gcatttgatg aataccttaa tgttatttta ttctggttta gtatttcctg
    15661 tccccttttt tacttatgca aatgtgttgg attttatagt aggtatatga ggcatagaag
    15721 cgaagttcaa tgagaaagtc tttttcagtc ttggggcaac atcaatttga aatacagcta
    15781 aagaaaaggt taggtgtaga caataccgtt gtcatgacaa gtcatcaaaa tgatgatagc
    15841 ttacatctgt tttagcatct ttggcctgtt tcagaatgaa atactctttg tcaagcatat
    15901 gcaaaataga tgagcagttt gacaatatac tggtgattgc cgaggtttag aaagccatta
    15961 tagaatcttt tgaggagtgc tatgaaaaaa ttattatctt atcttgggag atttcgttat
    16021 tttgcccttc tggtgtttat gctgggggga ttttctagta ttttacaatc acttgttatt
    16081 caaagagtta ttgccattga tacggtatca gattttaggt ctctttggaa actctttatt
    16141 gtggggcttt tgacctatct attattttat ggattggaat ttggtgccaa tgtggtttat
    16201 gatgtggctt gtaagcggat catgttagct ttacgagata agctgacgag aaagctgcta
    16261 ctatcgggtc aagcaataga ccagcatgag gcaacgaatt ttcttagtca ggacctagag
    16321 tttttctatg ataactatgt cacacaagtc atgcgtctgc ctaaggatgg gatgattttt
    16381 cttgtcgtgg cgatatacct gattacattg aacccgcttc ttgcctttct ttttattgta
    16441 ggttctttgt tacgtccctt gcctcagtta tttttgaccc aaacaacaga atccctaggg
    16501 aaaaggcaga gtgatgagcg cgaacgttcc atgtccttaa taatggatta tgtgaatggt
    16561 agtagtactc tattacatca tcaggccttt gaaagtacct atgatcaatt agcaaatcag
    16621 gtcttaacct acgagactgc tcgtcgtaac tattattacc tgtccaattt tctttttttc
    16681 tgtaatggtc tgactcaatt tttaggtaga gtagtgccga ttggccttta ttttttatta
    16741 ccaatggttt ttggtcatat cccagtatcg tcacttatcg ccatgtttat ggcatcaaat
    16801 catttagcga atcccttgca aaatatgatg tatgccactt ttagcatgca ggccgcagtc
    16861 tctgtaaaag ctaagattga tgatatgatg gatcaggtag ctgatgaagc agaaactcct
    16921 tatgtaccat attttaaagc tctggctttg gaagggatca caaagtccta tggcgccaag
    16981 ctgatcctta aggatttttc ctataccttt gaacagggga aaaaatattt gataaagggt
    17041 gccagtggta gaggtaagtc gactctgtta cacattatta agggagctgc tgttgactca
    17101 ggtaaaatag cgtttatcac caaagacaag caatcatttg aaaactatca agctaacgtt
    17161 ggcatggtga atcaggctcc ttttctcttt aatggcacct tggaagaaaa tgtctgtctg
    17221 aatcaggagt tttccaagga ggatatcctt gctgtcttgg accaagttca cctgttggag
    17281 gaattaccag ctggtctagg ctttcagata gaaaataatg gaaccaacat ttcgggtggc
    17341 cagcgagtgc gcatagaatt ggctcgattt ttgctacgtc agaaggatat tttattgctt
    17401 gatgaggtca cagcagcctt ggacaaggac aatgctcggc gagtaaggga gctgattttt
    17461 tctcttccta ttaccatcat tgaggtggct catcatgtgg atcaagctat agcttatgat
    17521 gatatgatag aattgtaggt gattaagatg tttaagtatt ttaataaata tctagtgaca
    17581 ctaacgcttg ttgcatgtgc cttaaacagt cttgtctttc tgattgaacc cttgatcact
    17641 agtaagattt ttgatttaac gtccttaaat aatcatcaag acaccttgtc ctttttaggc
    17701 tatggtctga ccttatacgt ggtcttatat tctgttatgt tcattgctaa tcttctgatc
    17761 aaccatatca tgacgattgg gtgtggtaga atcaggctgc gtctctatca gaatttaatc
    17821 ttaaatcatc gggagatgag tcatgacaag aaaatttcta tgctgactca agatgtagaa
    17881 tattatctat ggaatcacat cagccctagc attcttctcg tatcacacgt gagtaatgtc
    17941 ctcctgctca gtgcttacct gttatcaaaa aacatgctaa ttggtcttat ttttattgca
    18001 tgcgcttttg tatttttagt ggttcagcat gtgattggtc aaaaggcaga gcaaaaaggt
    18061 agtgagctgg cagtagcgag acaaaagctg cttggcttat taagtgatgt ggttgcgggg
    18121 cgttcgacat tgactcaaaa tcaagctctt tttgctagcc tcaaacaggt aaaaaaacag
    18181 tcagagcatt atgagagctc acgtcaagga tttgagatat ttaggtcttt ctttacccta
    18241 ttggcacatc tgatgctgtt tatttctcaa tttttgccca tttttttagg cttagcctta
    18301 accttattag gtgttaagct gagaacaact gatcttattg ccatgtttat tgcagcaaca
    18361 cgcttagaac agccactcaa aaatattgtt gatgatattt ttaggcttaa tggtgcaaaa
    18421 gccattgcca agcattttga gacactttta gagcagccta ttccaaaata tcagtcgcat
    18481 gctatgacag gtgatccttt tgaatgttta gatggtcatc atctggcgaa atcatttgca
    18541 ggtaggacct tattttccga tctctctttt cattttgaga agggaaagaa atacttgatt
    18601 aagggaccaa gtggatctgg taaatccaca ctctttaagc ttatcttaca ggagatgagt
    18661 cctgatgagg ggacactaga tatggtattg gctggaggtc agacgactga taattaccac
    18721 catcgcatag ggctgattgc gcagtcgcct tatcttttta acgatagcat tcggtataat
    18781 ttgaccttgg gggaggcgtt ttctgatgag ttgcttttag aaaagctaga acaggttggc
    18841 ttgactgatg aatttgacga tattttaaac taccaaattg ttaataacgg agaaaatatc
    18901 tcaggtggtc aaaagacacg tcttgaaatc gcaagaagcc tcattagaca aaaagatgtt
    18961 cttctagcag atgaagtgac ggctccactt gatgtcaaca atgctaaaac tatccgacag
    19021 ctactattta gtttaccggt aacagttatt gaaattgctc atcatattga tgacaccttt
    19081 atctatgacg gtgatattga tttatcgtag aaaatatcat cacattgctt agaaataata
    19141 attgatgctt atgaaattgt cattcacaca gtgaatggct ttttcttagg ctaaattctc
    19201 cacgtggagc ttgatccgat aggctatctg agaaaaaaag ctaacaacag ccatgttttt
    19261 tttggctatg actgttctaa tacgagctgc ctctaactgc tggtatataa gaggtgacat
    19321 gattgtcaca attcgtcatc attttgtcgt taagttttta catagatttc ttatgctagt
    19381 catggtagag ctccttaccc taaaaagaag ggaatttagc tgatgggaaa tagcaattct
    19441 aaagccttta tgataaaatg aaaaaagaca ctataataga agaggtaact gtatggaagt
    19501 ggcagaaatg cgccagcaaa tagtagaaaa caaagagaag ttgactagct tcaggaggtc
    19561 tctttgactt agagcgcttg gaagaggaca tagctctttt agaaaataag atgacagagc
    19621 ctgatttttg gaatgataat atggcagctc aaaaaacctc tcaggaatta aatgagctca
    19681 agctaaccta tcaaaccttt cataatatgc aggagctatc tgatgagaca gagctttatt
    19741 tagaaatgct tgatgaggac gatagcgtca aggaagagct agaagcaagc cttaccagac
    19801 ttagccagat gctagcaagc tacgagatga cgttgctctt gtctgagcct tatgaccata
    19861 gcaatgcaat cctagaaatt cacccaggtt caggtggcac tgaggcacag gactgggcag
    19921 atatgctttt tcgcatgtat actcgctttg gaaatgccaa gggctttaag gtagaaactc
    19981 tggactatca agcaggggac gaagcaggaa taaagtctgt gactctttct attgaaggac
    20041 caaatgctta tggcttctta aagtcagaaa tgggggtgca tcgtctggtg cgtatttctc
    20101 cttttgactc tgctaagcgt cgtcacacct cctttgtttc agttgaagtc atgccagagc
    20161 ttgatgatac catcgaggtg gagatacgtg atgatgacat taagatggac accttccgct
    20221 caggtggtgc tggtgggcaa aatgtcaaca aggtctcaac tggggtacgc ttgacccata
    20281 tcccaacagg aatcgtagtg gcgtcaacag ttgaccgcac ccaatatggc aaccgtgatc
    20341 gcgctatgaa aatgcttcaa gccaagcttt atcagttaga gcaggagaaa aaggcagaag
    20401 aggtcaatgc cctcaaggga gataaaaagg agatcacctg gggcagtcag atcaggtcct
    20461 atgtctttac gccttatacg atggtgaagg atcatcgtac caattttgag gtggctcagg
    20521 ttgataaggt gatggacgga gatattgagg gttttattga cgcttatctc aaatggcgca
    20581 tgggtgagga ttaaagtgat ccccactcag ataaacacta acagcttaga gaaggaagaa
    20641 taagatggca ttaattgaaa tgaagggtgt ttctaagaaa taccgtcgct cgacaacagc
    20701 tctgagagac attaatgtct cagtcaatca aggggaattt gtctatattg ttggtccatc
    20761 aggagctggt aaatcaacct ttatcaagct tctttatcgc gaagaaaagc taagctcagg
    20821 cagcctaaaa gtgggtgagt ttgacttaac caagctaaga ggacgtgagg ttccaatttt
    20881 acgtcgcagc attggtgttg tttttcagga ttataagttg ctccctaaaa aaacggtctt
    20941 tgaaaatgtt gcctatgcta tggaggttat cggagagaga cgtcgccata tcaaaaagcg
    21001 tgttcctgag gttctagacc ttgtcgggtt aaagcataag atgcgctcct ttcccaatca
    21061 attgtcaggt ggtgagcagc agcgtgttgc gattgcacgc gctattgtga acaatcccaa
    21121 gctcctcatt gcagatgagc ctacaggcaa tttggatccg gaaatttctt gggaaatcat
    21181 gcacctgctt gagcgtatca atctacaggg gacaacgata ttaatggcaa cgcataacag
    21241 tcatatcgtt aatactcttc gccatcgcgt ggttgcgatt gaaaatgggc gtattgtccg
    21301 cgatgaggag aaaggagact atggttacga tgattagaca ttttttccgt catatctggg
    21361 aatctatcaa aaatttaagg cgtaatctcc tcatgacctt tgcgtcagtc agtatggtga
    21421 ccgtcacctt aaccctgctt ggggtctttg ctgcaaccct gctgaacatt caacgtgtcg
    21481 cttctggcgt ggaaaacaac attcaaatca atgcttattt gcaggttgat tcgacagatg
    21541 ctgccaaggt ggttcagtcg attaatggag agcaggtgaa taacgagaat taccataaga
    21601 tttatgatca gattgcaggg ctaaagggcg ttgagaggat tattttctca agcaaggacg
    21661 agcagctgca aaagctacag gatagtctgg gcgatgtctg gggcatgtac aacgaggata
    21721 gcaatcccct gcaagacatc tatatcgtgg aaaccaagac ccctaagcag gtcaaatcag
    21781 tcactaaggc tatcaaaaag attcaaggga ttgaagatgc ggactatggt ggtatcaatt
    21841 cggataagct ctttaagttt tcaaagctga tccaaacatg gggcattatt ggaacgctgt
    21901 tgctcttgtt tattgcaatc tttctgattt ccaataccat tcgcatgact atcatgtctc
    21961 gtcagcgcga tattgcgatc atgcgtctgg ttggtgcgaa aaattcttat attcgtggcc
    22021 cgttcttttt tgaaggggca tgggttggtc tgcttggtgc gatattgcca tcgttgattc
    22081 tttattatgg ctacgagttt gcctacaagc atttcacccc agaattgcag cataatagcc
    22141 tatctatgta ccctatcaat ccatatgttt attacttgat tggtctgctt tttgtgattg
    22201 gtattatcat tggatcacta gggtcagtct t
//
