LOCUS       NZ_CP065054            23775 bp    DNA     circular CON 17-MAY-2024
DEFINITION  Streptococcus equi subsp. zooepidemicus strain SEZ13 chromosome,
            complete genome.
ACCESSION   NZ_CP065054
VERSION     NZ_CP065054.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus equi subsp. zooepidemicus
  ORGANISM  Streptococcus equi subsp. zooepidemicus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Complete genomes of eight Streptococcus equi subsp. zooepidemicus
            strains isolated from mares in estrus with endometriti
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2021) Microbiology, Immunology, and Pathology,
            Colorado State University, 2025 Campus Delivery, Fort Collins, CO
            80523, USA
  REMARK    Annotation added by submitter
REFERENCE   3  (bases 1 to 2150055)
  AUTHORS   Borlee,G.I., Lakin,S.M., Kapuscinski,M.L., Abdo,Z., Stenglein,M.D.,
            McCue,P.M. and Borlee,B.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2020) Microbiology, Immunology, and Pathology,
            Colorado State University, 2025 Campus Delivery, Fort Collins, CO
            80523, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Coverage                   :: 246
            Sequencing Technology :: Illumina NextSeq;Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015689395.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 02:47:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,059
            CDSs (total)                      :: 1,970
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 16 of 37
            Pseudo Genes (incomplete)         :: 20 of 37
            Pseudo Genes (internal stop)      :: 16 of 37
            Pseudo Genes (multiple problems)  :: 14 of 37
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:11:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 534276
            Orig. end                         :: 558051
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP065054.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23775
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="3"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23775
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23775
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13775](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13775
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            94..1725
                     /db_xref="GeneID:83704350"
                     /locus_tag="I2432_RS02650"
                     /old_locus_tag="LJFMMFNO_00533"
     CDS             94..1725
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /locus_tag="I2432_RS02650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00533"
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="WP_206156389.1"
                     /transl_table=11
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDKY
                     TSNPFFGILVGMAMSALIQSSSGVTVITVGLVSAGLLTLQQAIGIVMGANIGTTVTSFL
                     IGFKLGDYALPMIFIGAACLFFTSNKKLNNLGRVIFGVGGIFFSLNLMGDAMDPLKSVS
                     AFQHYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPILLGSN
                     IGTCITAVLAAIGSNIAAKRVAAAHILFNVIGTVIFMILLMPFTSFMLWLQSVLALSPE
                     MTIAFSHGTFNITNTLLLLPFISTLAKLVTTLIPGEDEIVKYEALYLDRLLITQAPSIA
                     LGNAHKELVHLASYAIQAFEASYSYIMTAEDRFGEKVRRYEKAVNTIDEELTTYLVDIS
                     NEALSPSENEVLAGLLDSSRDLERIGDHSESLATLIEGITAKQIDFSAAARGELTEMYH
                     LTHCLTLDAIRAIVDSDKALAQSIVERHRTIEQKERQLRKTHIERLNRGECTAQAGINF
                     IDIISHYTRITDHALNLAEKVLSGQL"
     misc_feature    1776..1791
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.47"
                     /tool="antismash"
     gene            1842..2990
                     /db_xref="GeneID:83704351"
                     /gene="nagA"
                     /locus_tag="I2432_RS02655"
                     /old_locus_tag="LJFMMFNO_00534"
     CDS             1842..2990
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006040 - amino sugar metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704351"
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /locus_tag="I2432_RS02655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00534"
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_012515125.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.2e-20, bitscore:
                     70.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGHWTATVDDQAEVIDY
                     TGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHLEQ
                     VSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAKGLI
                     KKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYAEAKKAVAAGASVWVHAYNGMRGL
                     THREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRAGGSPD
                     GDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHMSSYVPA
                     ASVGIDDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     misc_feature    1874..1889
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.37"
                     /tool="antismash"
     gene            3077..3916
                     /db_xref="GeneID:83704352"
                     /locus_tag="I2432_RS02660"
                     /old_locus_tag="LJFMMFNO_00535"
     CDS             3077..3916
                     /codon_start=1
                     /db_xref="GeneID:83704352"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /locus_tag="I2432_RS02660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00535"
                     /product="aldo/keto reductase"
                     /protein_id="WP_165627892.1"
                     /transl_table=11
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLGAIKAGYRHID
                     TAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYVDL
                     YLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTATITP
                     AVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTVAQLA
                     LAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDTKDF"
     gene            3967..4170
                     /db_xref="GeneID:83704353"
                     /locus_tag="I2432_RS02665"
     CDS             3967..4170
                     /codon_start=1
                     /db_xref="GeneID:83704353"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I2432_RS02665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269205574.1"
                     /transl_table=11
                     /translation="MVKTPQLLLADEPTGALDIEAEQEVLQAIRACQTEDMIVLMATHS
                     DEVAAQCDAIYHIEDLCLRQAK"
     misc_feature    4364..4380
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.75"
                     /tool="antismash"
     gene            4437..4970
                     /db_xref="GeneID:83704354"
                     /locus_tag="I2432_RS02670"
                     /old_locus_tag="LJFMMFNO_00536"
     CDS             4437..4970
                     /codon_start=1
                     /db_xref="GeneID:83704354"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1150: isoprenylcysteine carboxyl methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /locus_tag="I2432_RS02670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00536"
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="WP_012515132.1"
                     /transl_table=11
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFLT
                     LLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLAKD
                     HKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREENRL
                     LSEVIIPNGTRPKS"
     gene            5358..6269
                     /db_xref="GeneID:83704355"
                     /gene="glyQ"
                     /locus_tag="I2432_RS02675"
                     /old_locus_tag="LJFMMFNO_00537"
     CDS             5358..6269
                     /EC_number="6.1.1.14"
                     /GO_component="GO:0009345 - glycine-tRNA ligase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704355"
                     /gene="glyQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515134.1"
                     /locus_tag="I2432_RS02675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00537"
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="WP_165623030.1"
                     /transl_table=11
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLR
                     AIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLERLG
                     INPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTY
                     GLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFETFEK
                     EAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVAKTFVA
                     ERKKLGFPLLDDASRVALLAED"
     gene            6635..8674
                     /db_xref="GeneID:83704356"
                     /gene="glyS"
                     /locus_tag="I2432_RS02680"
                     /old_locus_tag="LJFMMFNO_00538"
     CDS             6635..8674
                     /EC_number="6.1.1.14"
                     /GO_component="GO:0009345 - glycine-tRNA ligase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704356"
                     /gene="glyS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /locus_tag="I2432_RS02680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00538"
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="WP_206156388.1"
                     /transl_table=11
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVQRMADFLKANRLSYDAIE
                     GFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVDDI
                     EFREVKGEEYVYVTKHEVGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVHSLI
                     VLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKERQEMI
                     IAQIRAIEAEQKVQVDIDEDLLNEVLNLIEYPTAFMGSFDPKYLEIPEEVLVTSMKNHQ
                     RYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQKLSVED
                     LVAKLAHVTFHEKIGSLAEHMDRTKVIAAFLADQAGLSEAEKSAVARAAQIYKFDLLTG
                     MVGEFDELQGIMGEKYALLAGEAAAVATAIREHYLPDSAEGELPETKVGAVLALADKLD
                     TLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYELSFESLTYQ
                     HKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPEMLARAEALVAASQLDTYKPA
                     VESLSRVFNLAKKAANAVPIDTSLFENDYERALAQAVDSLVLSGSAKEQLAQVFALSPV
                     IDDFFDHTMVMTENEAIRCNRLALLAELVKKVETIAAFDRLNTK"
     gene            9212..9469
                     /db_xref="GeneID:83704357"
                     /locus_tag="I2432_RS02685"
                     /old_locus_tag="LJFMMFNO_00539"
     CDS             9212..9469
                     /codon_start=1
                     /db_xref="GeneID:83704357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /locus_tag="I2432_RS02685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00539"
                     /product="DUF896 family protein"
                     /protein_id="WP_012515137.1"
                     /transl_table=11
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVR
                     HHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     misc_feature    complement(9927..9945)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 26.66"
                     /tool="antismash"
     gene            10001..10165
                     /db_xref="GeneID:83704358"
                     /locus_tag="I2432_RS02690"
     CDS             10001..10165
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704358"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03602"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /locus_tag="I2432_RS02690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="WP_012678394.1"
                     /sec_met_domain="TIGR03602 (E-value: 1.7e-18, bitscore:
                     63.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQFTSNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTINN
                     NYGAAEPKA"
     gene            10393..11343
                     /db_xref="GeneID:83704359"
                     /locus_tag="I2432_RS02695"
                     /old_locus_tag="LJFMMFNO_00540"
     CDS             10393..11343
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704359"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985278.1"
                     /locus_tag="I2432_RS02695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00540"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_206156387.1"
                     /sec_met_domain="PF00881 (E-value: 5.9e-26, bitscore: 88.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVLK
                     TSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYFED
                     RANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAIIKEG
                     MTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQEDIRAF
                     AEYGPITAENCNVILIYVYHYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTALVYGSV
                     DIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     aSDomain        11340..11609
                     /aSDomain="Cytolysin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing discrete C protein in a
                     SLS/cytolysin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_I2432_RS02700_Cytolysin_C_RRE.1"
                     /evalue="4.50E-36"
                     /identifier="RREFam014.1"
                     /label="I2432_RS02700"
                     /locus_tag="I2432_RS02700"
                     /protein_end="90"
                     /protein_start="0"
                     /score="114.0"
                     /tool="antismash"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEAY
                     YSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLML"
     gene            11340..12404
                     /db_xref="GeneID:83704360"
                     /locus_tag="I2432_RS02700"
                     /old_locus_tag="LJFMMFNO_00541"
     CDS             11340..12404
                     /codon_start=1
                     /db_xref="GeneID:83704360"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03603"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytolysin_C_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /locus_tag="I2432_RS02700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00541"
                     /product="streptolysin associated protein SagC"
                     /protein_id="WP_206158974.1"
                     /sec_met_domain="Cytolysin_C_RRE (E-value: 3.2e-34,
                     bitscore: 114.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03603 (E-value: 3.5e-115, bitscore:
                     381.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEAY
                     YSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMKVL
                     TGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQETDV
                     TSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLGFVDG
                     PFIHGCTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPLLNVLM
                     NLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALAKLRYEDQQI
                     STREIVKKLLQEES"
     gene            12417..13775
                     /db_xref="GeneID:83704361"
                     /locus_tag="I2432_RS02705"
                     /old_locus_tag="LJFMMFNO_00542"
     CDS             12417..13775
                     /codon_start=1
                     /db_xref="GeneID:83704361"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /locus_tag="I2432_RS02705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00542"
                     /product="YcaO-like family protein"
                     /protein_id="WP_021320450.1"
                     /sec_met_domain="YcaO (E-value: 1.2e-61, bitscore: 206.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 3.5e-103, bitscore:
                     342.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKSV
                     TGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRIVY
                     ASYRELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFFEDK
                     EMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSMMLSW
                     HTKKPCPKVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILKNKYKE
                     GPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLFLDLDSN
                     VFYYAHPKDQELKWEAFEPLISGEVRLSDLTSHAGKDKKEDLKTLLAYTKKVSPNAVFL
                     DITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHPMP"
     gene            13750..14421
                     /db_xref="GeneID:83704362"
                     /locus_tag="I2432_RS02710"
                     /old_locus_tag="LJFMMFNO_00543"
     CDS             13750..14421
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704362"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /locus_tag="I2432_RS02710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00543"
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="WP_206156386.1"
                     /sec_met_domain="Abi (E-value: 1.8e-08, bitscore: 31.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRAV
                     LVYYALVLTGIYLLSPSIKVPLGHSDGRLLFIGFILSFVVLFVEVAFLHISRCWQKKEW
                     LPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSLCYA
                     LNHFLMGRSIFYAKIVTGLIYGSIYYVSQSFWLVLLVHVGGNLWVEGLSHLQSMHKKVV
                     R"
     gene            14418..15104
                     /db_xref="GeneID:83704363"
                     /locus_tag="I2432_RS02715"
                     /old_locus_tag="LJFMMFNO_00544"
     CDS             14418..15104
                     /codon_start=1
                     /db_xref="GeneID:83704363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622426.1"
                     /locus_tag="I2432_RS02715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00544"
                     /product="SagF family protein"
                     /protein_id="WP_206156385.1"
                     /transl_table=11
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAVSYQQWLDL
                     LLGLIQLGLVVVCLLFSDALALDGLLAFLGRVSFGWPIICYVLLYGIALVELTLLVLVL
                     LFDLMLKKDSRLLLGKMTWLAFKLDRAAASFLLLSLVTLVDAFCYLGLCLFLGKGSVAG
                     LTIVVLGYALVKACRYSGWLQQLLAICLFSVIGVWCVTAALLYGWLIGLLLLTLTYLLI
                     SFKEQH"
     gene            15127..16050
                     /db_xref="GeneID:83704364"
                     /locus_tag="I2432_RS02720"
                     /old_locus_tag="LJFMMFNO_00545"
     CDS             15127..16050
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704364"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /locus_tag="I2432_RS02720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00545"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_206156384.1"
                     /transl_table=11
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKST
                     LINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGSLY
                     GLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDEPTV
                     GIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQAELE
                     RRYEADFTKQIMVTVAADQAIDLSDKPNWRLMDNELEAVLLIENEDIGSVVRQLTDAHI
                     AFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            16059..17186
                     /db_xref="GeneID:83704365"
                     /locus_tag="I2432_RS02725"
                     /old_locus_tag="LJFMMFNO_00546"
     CDS             16059..17186
                     /codon_start=1
                     /db_xref="GeneID:83704365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /locus_tag="I2432_RS02725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00546"
                     /product="SagG family ABC transporter permease subunit"
                     /protein_id="WP_206156383.1"
                     /transl_table=11
                     /translation="MVLFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFNT
                     AATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGALTA
                     ALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKRKID
                     YIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTGVSNS
                     AILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGPNDWQIIGVTASLVYLSVAIGIGLA
                     TGIRNQSFLTVASNAVIPIFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDSLFYLIF
                     GGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            17183..18301
                     /db_xref="GeneID:83704366"
                     /locus_tag="I2432_RS02730"
                     /old_locus_tag="LJFMMFNO_00547"
     CDS             17183..18301
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:83704366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /locus_tag="I2432_RS02730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00547"
                     /product="ABC transporter permease"
                     /protein_id="WP_042670190.1"
                     /transl_table=11
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQAK
                     IGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEERAIDQYLKAKTLEAVLTIEPGFGEKV
                     LKGDTQKLALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTKLSY
                     KVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSRLSRL
                     QYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFGLMIGA
                     VSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIISTFQNGG
                     NLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(18434..19714)
                     /db_xref="GeneID:83704367"
                     /locus_tag="I2432_RS02735"
                     /old_locus_tag="LJFMMFNO_00548"
     CDS             complement(18434..19714)
                     /codon_start=1
                     /db_xref="GeneID:83704367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622430.1"
                     /locus_tag="I2432_RS02735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00548"
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="WP_206158975.1"
                     /transl_table=11
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGSARILAEQYYGWNDGTRYAS
                     PLFLYVTPTNESQRKTENSNVVYCFNRDKEWPENWESVYPTPESIPYPYKLPLYNKLTG
                     TTETFKQNASNPRQIGDIGKALVAVLANGYPNKQLSHDNTKSRILTQLAIWYFSDSFDK
                     QYFKDNYHLTEEENKSLMNLIETGEKAAKGHEQPTYHLDIYVTTQQSYDRHKPFQNLLG
                     STLVPLPKPGPKPKPEPQPKPEPEPKPDPEPKPEPQPEPKPDPEPKPDPEPKPDPEPKP
                     QPEPKPQPEPKPEPMPKPDPELKPDPEPKPDPEPKPMPEPQPKPEPQPKPEPQPKPEPQ
                     PEPEPMPKPEPEPKPTPQPETKPQPKPAPQSEAKPQKPTKPSNATSQSSGKGLPRTNEA
                     GSLMTGLGTGLLSLLGLGFLTRRKRKD"
     misc_feature    19802..19816
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.38"
                     /tool="antismash"
     misc_feature    19836..19849
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.49"
                     /tool="antismash"
     misc_feature    19837..19850
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.95"
                     /tool="antismash"
     gene            complement(20024..21967)
                     /db_xref="GeneID:83704368"
                     /locus_tag="I2432_RS02740"
                     /old_locus_tag="LJFMMFNO_00549"
     CDS             complement(20024..21967)
                     /codon_start=1
                     /db_xref="GeneID:83704368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623219.1"
                     /locus_tag="I2432_RS02740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00549"
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="WP_206158976.1"
                     /transl_table=11
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWEDGKHENP
                     SFLYVTPAINSVRDLSKQRVVYCFNKTKFYPDPWEERFHNVSSIHNGLPVYDRISGDDN
                     TFKSNASNFRNTVPEITKTLVSLLSKGYPNSNLGLSDSSARKVTQLAIWYFTDSYPKES
                     FRTNYGLTETEEQKLFELITIGEKAELNKKQTLDLYIYKSGGYKKYGYQNLLGTHLISK
                     SPVPDIPYKENCQCYKLTFEAGRQGYNNGYWIITYNDKNKNGRYDKDLNEEIDRIFIKH
                     GLDGPRGEKGDPGKPGRDGLDGKPGERGERGPKGDTGPQGPRGDKGETGERGPKGEKGL
                     DGKPGEKGPKGDTGKDGAPGRDGQNGKDGQPGPKGDPGKDGENGKDGQPGPKGEKGDPG
                     QQGIPGPKGDPGKDGQDGKDGQPGPKGEKGDPGQQGIPGPKGDPGKDGQDGKDGQPGPK
                     GEKGDPGQQGIPGPKGDPGKDGEKGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGP
                     QGERGEQGPQGERGEQGPQGERGEQGPRGENPTPTPDPMPHPMPDPAPKPMDPKPEPKP
                     TPQPETKPQPKPAPQSEAKPQKPTKPSTITSQSSGKSLPKTNDTGSLITVLGTGLLSLL
                     GLGFLTRRKRKQ"
     misc_feature    22096..22109
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.49"
                     /tool="antismash"
     misc_feature    22097..22110
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.95"
                     /tool="antismash"
     gene            complement(22361..23446)
                     /db_xref="GeneID:83704369"
                     /locus_tag="I2432_RS02745"
                     /old_locus_tag="LJFMMFNO_00550"
     CDS             complement(22361..23446)
                     /codon_start=1
                     /db_xref="GeneID:83704369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /locus_tag="I2432_RS02745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LJFMMFNO_00550"
                     /product="hypothetical protein"
                     /protein_id="WP_206156380.1"
                     /transl_table=11
                     /translation="MMIRYFYKLLLTILILALGGFSLSACHSKISKPYQVAIFDKDHVR
                     TFMEKADSLVPVETVSRTQHKLFERESFKQANQGYFAKTREGNDLKILLTHIDQASLEE
                     KVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDCHLKKQAHKSIPNRDTINASNQF
                     LVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRTLYIT
                     QAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIENDQHYN
                     PDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSSYYFLFPKKLYRYDCSSHQMT
                     CINLDQYGVTHAHAMIAKPTP"
ORIGIN
        1 tgagcactat ttaaaaggat taaaaaaccc ttgtgataac tgaataaata cattaaaata
       61 gaagagaata aataagcgag tgaggacaat attgtgtcgg taaattggca agacattgcg
      121 tttcattttt ttgggggtct aggtcttttt cttttcagta tcaaatacat gggagacggc
      181 ttgcagcagg ccgcaggtga taagcttagg tattacattg ataaatacac aagcaacccc
      241 ttctttggta tcttagttgg aatggctatg tctgctttga ttcagtctag ctcgggtgtg
      301 acggtgatta cagttggcct agtatctgca ggccttttaa ccctacagca ggcgattggt
      361 attgtcatgg gggccaatat tggaacgacg gtgacctcct ttttgattgg ctttaagctg
      421 ggagattacg ccctgcccat gatttttatt ggggcagcct gtctcttttt cacgtcaaat
      481 aaaaagctta ataacctagg tcgtgtcatc tttggtgtgg gagggatttt cttctccctc
      541 aacctaatgg gcgatgcgat ggatccttta aaatcagtct cagcctttca gcattattta
      601 gcgacacttg gagacaagcc ctttcagggt gtttttatcg ggacagcatt gaccatgctg
      661 attcaatcct cagcggccat cattggtatt ttacaggggc ttttttcggg cggtctgttg
      721 accttgcagg gtgctattcc tattttgctt ggctctaaca ttggtacctg tatcacagcg
      781 gttttggcag ctataggctc taatattgct gctaagcgtg ttgccgctgc tcatattctt
      841 tttaatgtta ttgggacagt catctttatg attttgctga tgccatttac ctcctttatg
      901 ctatggcttc agtctgtttt ggccctgtca cctgagatga ccattgcctt ttcacatggg
      961 acctttaaca tcacaaatac cctgttgctg cttcctttta tcagcactct ggcaaagctt
     1021 gtgactacct taattccagg tgaagacgaa atcgtcaaat atgaagcctt gtatttggac
     1081 cgtttactaa tcactcaggc tccttctatt gccttgggaa atgcccataa ggaattggta
     1141 catctggctt cctatgctat tcaggccttt gaggcctctt atagctacat tatgacagca
     1201 gaggacaggt ttggcgaaaa ggtgaggcga tatgagaagg cggtcaatac gattgatgag
     1261 gagctgacca cttaccttgt tgatatttcc aatgaagccc ttagtcctag tgaaaatgag
     1321 gttttagcag gtctgttgga ttcgtctcgt gatttggagc gaattggtga ccactctgag
     1381 tcgttggcga ctctcattga ggggattaca gcaaagcaga ttgacttttc agcagctgca
     1441 cgtggtgaat taacagaaat gtatcacctg acccactgtt taactttaga tgcgattagg
     1501 gcgattgtgg atagtgacaa ggctctagcc cagtctattg ttgagcgtca taggacgatt
     1561 gagcaaaaag agcgtcaatt gcgtaaaaca cacatcgaac gcctcaatcg tggcgaatgc
     1621 acagcacagg cagggattaa ttttattgac attatatctc attacacacg tatcactgac
     1681 cacgccctaa atctagctga gaaagtactt tcaggacagc tctaataaaa gggaaaactt
     1741 gaaatagtat tcaggttttt ctttttaaca gaaggactgg tatataccat ttacaaaata
     1801 agaattaagg cgtataataa acgaaaaagg gaggaaaaaa gatgacaagc tatattaaag
     1861 cagattgctt ttattacccc aacgaggtaa agccagcagg ctatttggag ctaaataatg
     1921 gcacatttgg tcattggacg gctactgttg atgatcaggc agaggttatt gattatacag
     1981 gctatcaaat agcaccagga cttgtagata ctcatattca tggctatgct ggtgctgatg
     2041 tgatggataa ttcagcagaa ggtctccatg ccatcagtga gggtctctta tcaacaggag
     2101 tgacctcctt cttaccgact accctaacgt caacctttga gcatctagag caggtgtctg
     2161 caaccgttgc ttctgttgct gatcaggtca aaggagcaaa gattcagggg atttattttg
     2221 aagggcctta cttcactgag gaatacaagg gagcccaaaa cccaatatat atgaaaaatc
     2281 ctcgcttaga cgaatttgca gcttggcaaa aagcagctaa gggcttgatc aaaaaaatag
     2341 ctttggctcc tgagcgtgat ggcgtagaag catttgtctc tgaggtgacc aagcagggtg
     2401 tcacagtagc tttaggtcac tcaaatggta cctatgctga ggctaaaaag gcagtagcag
     2461 caggagctag tgtttgggtt catgcctaca atgggatgcg tggcttgact catcgtgagc
     2521 ctggtatggt tggagctgtt tataatattc ctggaacggt tgcagagctg atctgcgacg
     2581 gacatcatgt ctcacctgtt gcttgtgata ttttgatgca gcaaaagggg catgagcatg
     2641 tggctttgat tacggactgt atgcgtgcag gcggttcacc agatggtgat tacatgcttg
     2701 gagagtttcc ggttattgtg gaaaatggca cagctcgctt gaaggatagt ggtaatctag
     2761 caggctctat cttaaaatta aaggacggca ttaaaaatgt tgttgcctgg ggaattgcaa
     2821 gtccagcaga agcaattcac atgtcctctt acgtcccagc tgcttcggtt ggtattgatg
     2881 atgtctgtgg ccaaatcaag gcaggtcatg ctgctgactt tattgttctt gataaggact
     2941 tagaattagt agcaacctac ctaaatggtc aaaaggcctt tgaggcttga tacagcaaag
     3001 gaattgggct agtgatcagc tcaattcttt ttgctttgct tatcattgtg ctacaatgaa
     3061 aaaggaggtt ttagatatga ttaaaacagt aacaatggct aatggtcttg ctattccagt
     3121 gcttggcttt gggaccttta aggctgctga tggtgaggag gcctaccaat ccaccctagg
     3181 agcgattaag gcaggctatc gtcatattga cacagctgcc atttatcaca atgaaaaaag
     3241 tgttggacag gccattcggg attcgggcgt tcctcgtgaa gagctcttta ttaccactaa
     3301 gctctggaat gatgctcata gctatgatgg cgctaaggca gccttagcag cctctcttga
     3361 gcgccttgga ctagagtatg tagaccttta tctgattcat tggccaaatc ctaaggctct
     3421 tagggattgc tggcaagcag ccaatgcagc agcttggtct tatatggagg aggctgttga
     3481 agcaggcttg gttcgctcga ttggtgtcag caactttatg gttcaccatc tggaggctct
     3541 taaacagaca gcaaccatta caccagcagt caaccagatt cgcttggcgc ctggctgcta
     3601 tcaaaaagag acggttgatt attgccgcag gcatcacatt ttgctagagg cctggggtcc
     3661 attaggacaa ggagagatat ttgccgatga taccatgcag gcattggcta aaaagtacaa
     3721 caagacagtg gctcagctag cccttgcttg gtctattgct gagggcttta ttcctctacc
     3781 taagtcggtg cacaaggaac gcatagtaga aaatatggct atttttgatt gtgagattag
     3841 tccagaggat tcagagcgca ttcgttgcct gccgggtatg tcagctatcc cagatcctga
     3901 taccaaggac ttttagcaag agctgcaggg attaagtggg ttgccttagt agcgcttgct
     3961 cgtgctttgg tcaaaacacc gcagctgtta ttggcagatg agccaacagg cgccctggat
     4021 attgaggctg agcaggaggt cttacaagcc atcagagctt gtcagactga ggatatgatt
     4081 gtcttaatgg caacacacag cgatgaggtt gcagcgcaat gtgacgctat ttaccatatt
     4141 gaggatttgt gtttacgaca ggcgaagtag gtcaggcctg caaaatgcct cttgggtgct
     4201 gcttgctgct cgtgaattga ctgagtctag gagctgtctt ttgatggtga tttggtacga
     4261 ccttaaagct ttgatgaggt ctcttgatgg tgctgtgtga cgacctcttg tttttagaga
     4321 tcaaagaaag acatcttttt tttgaaaacg gtttgacaag gctttgtaac ttagctataa
     4381 ttttaattag tgtttcgtga aagaaacaga ttaaactaga ataaaggagt cttactttga
     4441 ttatcctgtt attgatgcta ttgatgtttg ctattcgttt agtattctta aaaaaatcga
     4501 tcaaaaacga gaaggctatc ctggctaatg gaggcaagga atttggtgcg caaaacacta
     4561 agtttttgac cctgctgcat atcatgattt atgtctttgc tgtgacagag gcattgctca
     4621 agcagattaa gtttgatggc attagctttc ttggcttgct gctgatgatt ttttcgatag
     4681 ctgtgctata tgaggtaact cggatcttgg gagatatttg gacagtgaag ctgatgctgg
     4741 caaaggacca taaatatgtc gatcattggc tctttaagac tgttaagcac cccaattact
     4801 ttttaaacat tgctccagag ctggttggta ttgctttgct ttgccatgct cagattacgg
     4861 caatgctgct tttcccttgc tatattattg tgatttatct gcgtattcgt gaagaaaata
     4921 ggctcttgtc tgaggttatt attccaaacg gaactcgtcc aaaatcataa tagttgatta
     4981 gacaatcata ggattttgtg ataaactaac caataggaaa gaaaatagca ggtttctgat
     5041 ctaaagcgag ctcggggctg gtgagagccg agtgatggta ctgctggttg gcgctttctc
     5101 taaagagcaa gctcaggtgt ttgtagcttg cttgacatct gtttatcaac aagatcaaat
     5161 gaagtaataa attagggtgg aaccgcgttt tgacgcccct atgcctttag gtgtaggtgg
     5221 ctatagacgc ggtttttttc tttgaaaaac tgtttaagag ccaaccataa gccaagttgt
     5281 cccaccttac gagccaagcc ttagccagcc tttggttagt gcctgctgta agatataaaa
     5341 aatagaaaga ggaaatcatg agtaacaaac ttacctttca agagattatt ttgacgctac
     5401 agcaatattg gaatgatcaa ggctgtatgc taatgcaagc ctatgacaat gaaaaaggag
     5461 cagggaccat gagtccttat accttccttc gcgctattgg tccagagcct tggaatgctg
     5521 cctatgtgga gccatctcgt cgtcctgctg acggccgata cggcgaaaat cccaatcgtc
     5581 tgtatcagca ccaccaattt caggtggtga tgaagccttc tccaagtaat attcaggagc
     5641 tttacctgca atctcttgaa agacttggga ttaatccatt ggagcatgat attcgatttg
     5701 ttgaggacaa ctgggaaaat ccttcaaccg gctcagctgg acttggctgg gaggtctggc
     5761 ttgatggtat ggagattaca caatttacct acttccagca ggtgggaggc ctagcaacat
     5821 caccagtgac agcagaggtc acctatggct tagagcgctt agcctcatac attcaagagg
     5881 tggattcggt ctatgatatc gaatgggcac ctggtgttaa gtatggcgag atttttcttc
     5941 agccagaata tgagcattcc aagtattcct ttgaggtatc caatcaggac atgctgcttg
     6001 aaaactttga gacctttgaa aaagaagcag agcgtgcttt agcacaaggg cttgtccacc
     6061 cagcctatga ctatgtcttg aaatgctctc atacctttaa cctgcttgac gctcgtggtg
     6121 cagtctctgt gacagagcgt gctggctata ttgctcggat tcgtcattta gctcgcagcg
     6181 ttgccaaaac ctttgttgca gagcgtaaaa agcttggctt cccattgtta gatgatgcta
     6241 gccgagtagc cttgctggca gaggactaag gagctggacc taaaccagct ccttgtagta
     6301 aatgcagctt gtatgatctt gtaagctcta gttgctgcta gcagcttacc tatctggtag
     6361 gtgcttttta aaagcgatga tgcttaaagg cctggtgact agtcctgtca agctcagtct
     6421 ttctgctaag tgatcttgtc taacaggcag cttattagca ggcttgcagg attaggagct
     6481 agtgatttgg tctcctaaac ctaccccata acttgaagaa aggaaagaaa gatgggacaa
     6541 atcttgtaga caaaggatcg tccaagcttg cccaaggcat gctaggatcg gtttgatctt
     6601 ctcttttaga tttgataccc ataggatttt aatgatgaca aaagatttac ttgtagaact
     6661 tggtcttgaa gagcttcctg cctacgttgt cacacctagt gaaaagcagc ttgtgcagcg
     6721 tatggctgat tttcttaagg ccaatcggct tagctatgac gcaatcgaag gcttttcaac
     6781 gccccgtcgt ttagcagtgc gtgtgctggg cttagctgat cagcagactg atctgacaga
     6841 ggattttaag ggaccctcta aaaaaattgc tcttgatgct gatggtcaat tttcaaaagc
     6901 cgctcagggc tttgttcgtg gaaagggctt gaccgttgat gacatcgaat tccgagaggt
     6961 caaaggcgag gaatacgttt atgtcaccaa gcatgaagtg ggcaagcagg ctaaggacgt
     7021 tttagcagcg gtgcccgagg ttcttgcttc cttgaccttc ccagtcagca tgcactgggc
     7081 taacaacagc tttgactata ttcgtccggt gcatagcttg attgtactgt tagatgatga
     7141 gcctttggag cttgactttt tagacattca ttcgggacgt atcagtcgcg ggcatcgctt
     7201 ccttggagaa gagactagca ttacaagtgc tgattcctat gaggctgatc tgcgcagcca
     7261 attcgtcatt gcctctgcta aagagcgtca agagatgatc atagcacaaa tcagagccat
     7321 cgaagcagag caaaaggttc aggtggatat tgatgaggac ctcttaaatg aggtgctcaa
     7381 cctgatagaa tacccaactg ctttcatggg aagttttgat cccaagtacc tggaaatccc
     7441 agaagaggtt ctagtaacct caatgaagaa ccatcagcgt tattttgtcg tgcgtgatca
     7501 ggctggcaag ctaatgccga attttatttc tgttcgtaac ggtaatgcta agcatcttca
     7561 aaatgtgatt aagggcaatg aaaaggtgct tgttgctcgt cttgaagatg gagaattttt
     7621 ctggcgtgag gaccaaaagc tatctgttga ggatttggtt gctaagctag ctcatgtgac
     7681 cttccatgaa aagataggct ctctggctga gcatatggac cggaccaagg ttattgcagc
     7741 ctttcttgct gaccaggctg gactctcaga agcagaaaaa agtgctgtcg ctcgtgctgc
     7801 ccagatttat aaatttgacc tgctaactgg catggttggg gaatttgatg agctacaagg
     7861 cattatggga gagaaatacg cccttttagc tggcgaagct gctgctgtcg caacagcgat
     7921 tcgtgagcat tatttgccgg attcggcaga aggagagctg cctgaaacaa aggttggtgc
     7981 tgttcttgct cttgctgata agttagacac cctgctgtcc tttttctctg ttggtttgat
     8041 accgtcagga tccaatgacc cttatgccct acgtcgtgca actcaaggga tcgtccgaat
     8101 tcttgagcat ttcggctgga gcattcctat ggataagctg attgatagcc tatatgagct
     8161 gtcatttgag agcttgacct atcagcataa ggctgaggtg ttggacttta tttgtgcacg
     8221 tgtggataaa atgatgggct cagccattcc aaaagatata cgtgaagcag ttttggctag
     8281 ctcaagcttt gttgtaccag aaatgttagc aagagcagag gctctggttg cagcaagcca
     8341 gctagacacc tacaagccag ctgtcgagtc gctgtctcgt gtctttaatc tagcgaaaaa
     8401 ggcagctaac gctgtgccga ttgatacgag tctctttgaa aatgactacg aaagggcttt
     8461 ggcacaggct gttgattcac tagtgttatc tggctcagcc aaagaacagc tagctcaggt
     8521 ctttgccctt agtccagtta ttgatgactt ctttgaccat acgatggtca tgacagagaa
     8581 cgaagccatt agatgtaacc gcttagcgct gttagcagag ctggttaaaa aggtagagac
     8641 cattgcggcc tttgaccgat taaatactaa ataattcgct gtgtaagatt aagcacatcg
     8701 ccctgtgtta gctgttcgta ttccctagat gatataggtg actgattacc tgccttggga
     8761 taagtccttc cctaagcact caagacttat caagcaattg atacttagtc aaatcagtcc
     8821 ctcttgcttg ctaggggata tcgtcttggg ctagctttgc tagcaatagc tgtgctggtc
     8881 agtggtcaat aaaagcatca ggatcgctgt tagtaaagtg agcatggatt ttagcttttc
     8941 acaagaagtt agctacagcc ttcttagcag aagcataagg ctaagcagct gctggcacag
     9001 ccttagatat agacaaaaag agtgcagtac tctatgtcac aaacgaaaga gaaaggatta
     9061 gaggcagccc catttgcagg aaacccttgc tggcaaagct ggtgaaaaag gacttgaaag
     9121 gtcctagtaa cggtcctaaa gagactgtct agcccatcat caagcctcat cagctgccca
     9181 ctgcttttgg tgcagccctt atatgtgatt tatggatcct aaaaaaatcg ctcgtattaa
     9241 cgagcttgca aaaaagaaaa aaacagttgg cttgactggt cctgaaaagg tagagcaggc
     9301 caagctgcgt gaggaataca ttgagggcta tcgccgctca gtgcgccatc acattgaagg
     9361 cattaagatt gttgatgaag acggaaacga tgttactcct gagaaattaa gacaggtgca
     9421 gcgcgaaaaa ggtctgcatg gacggtcact tgatgatccg gaatcttgat tattaaatga
     9481 atataaatat tttgccatga tttaatgtta ctaatgagaa aaagataaac aaagacaaat
     9541 agctttaatc attaggtctt tcggcaaaag agtcattatt tttagaaatg gttaattgtg
     9601 aggcactaac catctgtctc atcaatacag ttgtaggtag agataataat atctctacct
     9661 attttaatgc gtttcattaa aaagactgat agtttataaa tgccattaaa gagataggct
     9721 taagactttg tcaagctcaa taagctaacc tttctgaaaa aaaataatga catttttgta
     9781 agaaaatatt aaagaaagca tttacatatg tcttgaattt taatataata tagttggtaa
     9841 gaattgaatg gtcactttaa caagggcgat acaaaatagc tagccttgtg ttgctggata
     9901 ctggctcatg attgcttttg ctatcagttg agaggtattc tcatttaact cttatcagtg
     9961 ttttgtttta ccgatcaggc gatataagga ggtaagcatt atgttacaat ttacttcaaa
    10021 tatcttagct actagtgtag cagaaacaac tcaagttgct cctggtggtt gctgctgttg
    10081 ctgttcttgt tgttgctgcg tctcagcttc atggggcaat actaccataa acaacaatta
    10141 tggtgcagct gagccaaaag cgtaaacttt aatacttcta tttaatagtt aatagctaga
    10201 tcacaatcat tagtttgcta gcgactaagg ttacagtttg taattgatgg tgttagctgg
    10261 tgttggatag gggtgttaca tgacaagaga cgaagacaat cagcttgatg tcaacgtctt
    10321 gtagtaatta gcaggtacta gtcggtacct gctaattact attatttatt aatatattac
    10381 aggaagacag ttatgccatt tttttctaag gaaaaacaac gttcggataa ccaaagtgac
    10441 ctaacaagag aagaagcacg acagttattt gaatttaata ccaatcactt atcgttatca
    10501 acctatcatc atcaaacggt attaaaaaca tcaaaacagc ttgtggcaca gcatttgatg
    10561 cctgatgaaa cagacaatct tagccaacgg tttttgatga attacaaggc taataacaat
    10621 tacctagggt ttaagaccag tgtggctgag ttttttacgg attctgcagt gaccaccttt
    10681 tcaaatagtg actattttga ggatagggca aacacgatag cacttcctaa agctaagaag
    10741 gtctcagcag ccctatcaac ctgtatcacc aaccggagaa gtcataggca gtttatagat
    10801 gaggagatgc ctttgcagga tttggctgat ttgctttatt atgcttgtgg tgtcagctct
    10861 caggcgatta tcaaagaagg catgactaag acagtagcct taagaaattg tgcttctggt
    10921 gggggtctgt accccatcac cttatttttc tatgcaagaa acgtagaaac actcaaggac
    10981 ggtttttatg aataccttcc ttatcagcac gccctgaggt gtcatcatct tagtgatcag
    11041 gaggatatta gagcctttgc cgaatacgga ccgatcactg ccgaaaactg caatgtcatt
    11101 cttatctatg tttatcatta catcaaaaac acacgtaaat atggaaatca agctactgct
    11161 tatgccttta ttgaagctgg agagattgct caaaatgttc aattggtctc aacagctttg
    11221 gtatatggaa gtgttgatat tggggggtac aataaggaat acctccaaga aaagctaggc
    11281 ttggatggct tgacccagca tgtgattcac atgacgatta ttggaaataa ggagtctcaa
    11341 tgaaatatca attaaatagc aatgttcgca ttgtgcaatt tgacgatacg ttttgcttta
    11401 gaaaaggcct atgggatttt aatgaagctg ttttagacat tgcacaagag ccacaagcct
    11461 taaaagaagc ctactacagt atcatctccg attggtttaa cgggaaggtt attgatactg
    11521 atacctacga aaaaacacta gagtctgact tatttgcaaa attgtcagag gtcatcacag
    11581 ccttgtatta taacgaccta ttgatgcttg aggacgctta tgctcttgaa gaaaatatca
    11641 tgaaggtctt aacaggcaat tatcatttca tagctgaatc aggacaggct aaggatactg
    11701 cacctgtctt atttatcagt gattcaagct atgtcaatga atctgctgag ctgctggcca
    11761 agcacctgaa cttaaacctt caggtggcta gcgatgagct aaaaatgctc attcaagaaa
    11821 cagatgttac ctctcgctta gatgctctgg agcaccatcg caacatgaag tgcttatctg
    11881 agaagctcgc agactatcag agtattgtta tttgtcaagg ccggttgaat attatgatgc
    11941 tgcgtcacct taatgaaatc agtgtggcct tgaaaaaaca attggtgctt ggctttgttg
    12001 atgggccatt tatccatggt tgtaccttaa atcctcctca tagtgctgat tttgatagct
    12061 tggagagaag ggtgctggca cgtctacagg accatacgct ttatcagcgc tttgcaagtc
    12121 agcagctgcc gccaacgcag cctgttagct cctcttatgt gcctttgtta aatgtgttaa
    12181 tgaatctggt tgtcagtgag gcctttatta tagctcaaac aggaagctca aaatttgaag
    12241 ggcgtttgtt aagtgtctat ttgccaacgc ttgagattca ggtgcaggat attttgaaaa
    12301 tgtctaattc tcagacacaa ggggctctgg caaaattaag gtatgaggat caacagattt
    12361 caacacgtga gattgttaaa aaactccttc aagaagagtc ataaggaggt ctaacaatgc
    12421 tacattatta cccttcgttc aaccatatcc ttgataagct aaagggcctt agtggtaacc
    12481 gaactggtat cttaaatcag tctcaggttc ctatttgtaa ccatcctcat gatgtttacc
    12541 taaagagtgt gacaggtcag atgcctgatt accacaagca gtttattggt gagctgagtc
    12601 aggtgagcta tcatatcatc ggttatggca gtcattatga ggaggccttg atcaaatact
    12661 taggtgaaag cattgagcgt tatgccactg ttattgctgg ggaattatta tcagaccgga
    12721 ttgtttatgc ttcttataga gaattgagcc agacagatcc tgtcatgccc ttagagtatt
    12781 tgcaggtttt tacacaggaa caaattgacc gttgtcatga tttgcacatg atcatgtgtg
    12841 ataaaatggt gacacaagac gatgtcttgg gctgggttaa gtgtccgatg ttttttgaag
    12901 ataaggagat gtatgtgcct gcccaaatgc tttgcgttgg ctataagacc aaccaggctg
    12961 taggcgaaaa gcacatcatt ccaggttttt caacggggac agcctctcat acaacactag
    13021 aagcagccat gtgtaatagc ttgattgagt atattcaaat tgactctatg atgcttagct
    13081 ggcatactaa aaagccttgt cccaaggtga ttattgatga tccggaaatt ctagctcttt
    13141 tggaggaagc tagacttggt aaggacagtc tctatgagat tatccctatt gacatgactg
    13201 ttggagagga taatccgctt tatacctttg gtattatcct caaaaacaaa tacaaggaag
    13261 gtccttatct cttatttggg gttcaggcag gcttggatcc taagcatacc ctgttaagag
    13321 gaatcatgga ggcctcagct attagctata gctattacta taatttgttt tataatccaa
    13381 cgtcaacaca aaatgctgag agtgattctc ccttgttctt agacctagat agtaatgttt
    13441 tttactatgc tcatccaaag gatcaggagc ttaaatggga ggcctttgag cccttgattt
    13501 caggagaggt tcgtcttagc gacctgacaa gtcatgctgg gaaagataaa aaagaggatt
    13561 taaagacact actagcttac actaaaaaag taagtcccaa tgctgtcttt ttagacatta
    13621 ctcctcctga ggcctcagaa aaaggctggt acgtgacacg tgtcctcact cctgagcttc
    13681 ttgagatgtg tattcctgcc tttccatttg ctaatcatcc acgtatgaga cagtttggag
    13741 gtgtgacaaa tgcctttgta cacccaatgc cttaacctat gctttttaat ggctaccttt
    13801 tgtccgtcga tcgcgatgca ggctattttt ggccaaggtc gtgatagcta tagctttaat
    13861 ctgataggct ttttaagagc cgtactggtt tattatgccc ttgtcttaac agggatttac
    13921 ctgctgtcac cttctattaa ggtaccctta ggtcatagtg atggtcgtct cttgttcatt
    13981 ggttttatct tgagctttgt tgtgctcttt gttgaggttg cttttttgca tattagccgc
    14041 tgctggcaaa aaaaagagtg gcttccctta gtcctatcat ttgtcggaac gacacaaaaa
    14101 tggccacaga taggctatcc cttggttttg gcctgctgtg aggaaatcac ctatcgtttg
    14161 atttggttta acatcttgtg gcttcaatgg cgattgccaa ttgctcttgt cttgttgatc
    14221 accagcctgt gctatgccct aaaccatttc ctgatgggca gatccatttt ttacgccaaa
    14281 atagtgaccg gtcttattta tggaagtatt tattatgtta gtcagagctt ctggctggtg
    14341 ttgcttgttc atgttggagg caatttatgg gttgaaggct tgagtcatct tcaatcaatg
    14401 cataagaagg tggtacgatg atcataatac tagcattact atccttttta atcctagtga
    14461 ccctttttct aacaagtcat aaaagacgtc gcttagtcag atggcattta aggcatatca
    14521 gggcagtgtc ctatcagcaa tggcttgatc tattgcttgg tctaatccag cttggcctag
    14581 tggttgtttg tctattattt tctgatgctt tagctcttga tggtttgctg gcctttttgg
    14641 gtcgagtatc ctttggttgg ccaatcattt gttatgtgct attgtatggc atagccttgg
    14701 tagagctgac cctgttggtt ctggtcttgc tttttgatct tatgctgaaa aaggatagtc
    14761 gcctactctt aggaaaaatg acttggctag cctttaaatt agatagggca gcagctagct
    14821 ttcttttatt aagtcttgtc acactggttg atgccttttg ctatttgggt ttatgtctct
    14881 ttttaggaaa aggctcagtg gcaggtctta cgattgtggt tttgggctat gccttggtca
    14941 aggcctgtcg ttactcaggc tggctacagc agctactagc catatgcctc tttagtgtga
    15001 ttggtgtctg gtgtgtgaca gccgccttat tatatggctg gctgattggt ttgcttttat
    15061 tgaccttaac ttatctgcta attagtttta aagagcagca ttagagttgg aaagaaggaa
    15121 taatatatga gttttgtaga gttaaaagat gttgtcaagg tctatcgagg cggcaaaaag
    15181 gcaatagatc atgtctcact gacaattgag gaagggagaa tctacggcct tttagggcct
    15241 aatggcgctg gtaagtcaac cttaatcaat gctattttag ggttaatccc tttgaatgct
    15301 ggcgaagtga ctgttttaca gcaatcttat aaatctattc gaaaaattag ttccaagatt
    15361 ggctatgtcc ctcaggatat tgctgtttat cctgatttaa cagcctatga gaatgttgag
    15421 cttttcggct ctctctatgg cttaaaggga agtgagctca aggagcaggt cctaaaaagc
    15481 ttggagttcg tagggttaaa atcacaggca agccagtttc caagtcagtt ttcaggaggt
    15541 atgaaaagac ggttaaacat tgcctgtgct ttggtgcatt ctcctaagct aatcatcttt
    15601 gatgagccga cggtagggat tgacccacag tctcgtaatc atattttaga gtctattcgc
    15661 ttgttaaatg agcaaggagc tactgttatt tacacgaccc actacatgga agaggttgag
    15721 gccttatgtg attacattta cattatggat catggtcagg tgattgaaga gggcagtcag
    15781 gccgagctag aaagacgcta tgaggctgat ttcacaaagc aaatcatggt gacagtcgca
    15841 gctgaccaag caatcgatct ctctgataag cccaattgga gattgatgga taatgagctt
    15901 gaagcagttc tcttgattga aaatgaagac attggctcag ttgttcgtca gttaacagat
    15961 gctcatattg cttttagtga gattaggcat aagcatttga atttagaaga aatcttcctg
    16021 catttgactg gtaagaagct aagagattag gggttgttat ggtcttattt catttaatca
    16081 aaaaagaaag cttacagatt tttagggatc ggactgcttt gttgatgatg gtggtttttc
    16141 ctatcttgat gattctgatt ttaagctttg cttttaagtc cagctttaat acagcagcta
    16201 ctgttcctaa attgacggtt cgttatcagc ttgagggcaa ggaaacagag tatcaaaaga
    16261 actttatcac gtttttaaag ctgttaaata aagagcttca tttagaagct aaagaaacca
    16321 aggatatcgc caaggctaag caaaaggtca gtgagggcgc cttaacagca gctctagagg
    16381 ttaagagcga tcaaaacatt gaggtgacca ccaacagcat taaccaacag aatgctgatt
    16441 tgattaatat gcttgtcaat atctatgtgg ataacgccaa gacctatgat tcgattgcta
    16501 acctttatcc agaagccatt agcaacatca agaaaagaaa aatagactat atcgcctcta
    16561 gctctgtgca aaccagtaaa ggcatgagct cagcggatta ctatgctatt tccatgttta
    16621 ccatgattac cttttatagc attatgtcag cgatgaatct ggtgctatca gatcgtcagc
    16681 aaggggtggc tagccgcatt tatttgacag gagtctcaaa tagtgctatt ttgcttggaa
    16741 aattaattgg tggtatgcta gcaacagcag tccagctaac cattctttat gtctttaccc
    16801 gatttgtgtt acgtgttaat tgggggccca atgactggca gattatcggt gtgacagcct
    16861 cgttagttta tttgtctgtt gccatcggta tcggacttgc gactggtatt agaaatcaat
    16921 cctttttgac ggtagcgtct aatgcagtca ttccgatctt tgcctttttg ggagggagct
    16981 atattccttt atcaacctta aatagcgcct tgattaatca gctgtctaat atttccccga
    17041 taaaatgggt caatgatagc ttgttttatc ttatttttgg tgggcaatcc aatcccatac
    17101 cggttacctt aatggttaat cttggcatag gaacagcctt tatcctcttt gctttggtca
    17161 gaatgagaaa gcaggtggca gcatgattcc ttttattaaa gctctattta tcaaaattag
    17221 acgtaaaaaa acaagctata tcacctttat cctgttgcct atgctaacaa caatgctggc
    17281 cttgtccttg agctttacag ggggaagtca agccaagatt gggatcttag ataaggataa
    17341 gagtcaggtt tccaagcaat ttgtgtcgca attaaagcac aataaaaagt atcagatata
    17401 tactaggcta gaggaaaggg ctattgatca atacctaaag gccaagacac tagaggctgt
    17461 gctgaccatt gagccgggct ttggtgagaa ggttctaaaa ggagatactc aaaagcttgc
    17521 actgcgttcg attgctgata gtcaaataac agaatggttt aaggcgcagg ctaattatct
    17581 cttggagaat tacaatatca ttggtgatgc ggcagcaggc aatcaagagg ttttcaagaa
    17641 gatttcagcc cataacacaa agctatccta caaggtcaaa gaaatcaccc tagctgatcg
    17701 ttcccaaagt aagtctgttt cctcgacaac aactggcttt ttattgatcc taatgctagg
    17761 cagtaccagt gtcttgtacg gtggtatctt gcttgataag tccagtcaaa tctacaatcg
    17821 cttagtctta tcaaggctat caaggcttca atacatgctg agctatgtct gtgttggtat
    17881 tgttgccttt gcgatacaaa tagtgattat gctgggatta ctcagggtag caaatgtcag
    17941 cttttatatt ccaacagcca ttgttttgtt gaccttcttc ctttatagtt tgttagctat
    18001 aggctttggc ttaatgattg gtgcagtttc taaaaatgcg caacaaagca gtcaattggc
    18061 taatctgatt gtgatgccaa cctctatgtt ggcaggttgt ttgtggccgc ttagtattac
    18121 gccgccttat atgcaggcga ttggaaagct actcccacag cattgggtgc taaccatcat
    18181 cagcactttc caaaatggcg gtaatctagg tgaggcttgg ccttatttct tggccttgtt
    18241 tgtagcagcc atgaccttaa tggtactagc aagcgtgctg atgaagcctt tacatcgcta
    18301 gactaagttg tcttaccctt tttgaacaaa gcttaaaaag ccttatcgtt ccatttatgg
    18361 cgcgataagg cttttgtgtt gtattagact agatactgat caactaaacg actacagata
    18421 atcttttagt gtcttagtct tttcttttgc gtcttgttag gaagcctaat ccaagaagag
    18481 agagtaagcc tgttccaagt cctgtcatta gactgcctgc ttcatttgtt cttggtagtc
    18541 ccttgccgct agattggcta gtagcgtttg acggcttggt tggtttttga ggtttagctt
    18601 ctgactgagg cgcaggttta ggttgaggtt ttgtctctgg ttgaggtgta ggtttaggct
    18661 caggttccgg cttaggcatt ggttccggct caggctgcgg ttctggttta ggctgaggtt
    18721 ccggtttagg ctgaggttcc ggcttaggct gaggttccgg cattggctta ggctcaggat
    18781 ctggcttagg ttcaggatca ggcttaagtt caggatctgg cttaggcatt ggttctggct
    18841 taggctcagg ttgtggctta ggctcaggtt gtggcttagg ctcaggatct ggcttaggct
    18901 caggatctgg cttaggctca ggatctggct taggctcagg ttgtggctca ggcttaggct
    18961 caggatctgg cttaggctca ggctctggtt taggctgcgg ctcaggctta ggcttagggc
    19021 caggtttcgg aagaggtact aaagttgaac caagaagatt ttgaaatggc ttatgcctgt
    19081 cgtaactttg ttgtgttgtt acataaatat ctaaatgata tgttggctgt tcatgtcctt
    19141 tagctgcttt ctctccagtt tcaattaaat tcataagaga tttattttct tcttcagtta
    19201 ggtgataatt gtctttaaag tattgcttgt cgaaactatc gctgaaatac cagatagcta
    19261 gctgggttaa tattctactt ttagtattat catgactcaa ttgcttattg ggataaccgt
    19321 tagcaagaac tgctactaga gccttaccaa tatctccaat ttgtctgggg ttactagcgt
    19381 tttgtttaaa agtttcagtt gttccagtta atttattata taaaggtagt ttgtatgggt
    19441 atggtataga ttcaggagta ggatatacac tttcccagtt ctctggccat tctttatctc
    19501 tgttaaagca atagactaca ttgctatttt ctgtttttct ctgactttca tttgttggtg
    19561 ttacatacag aaaaagtggc gatgcatacc tagttccatc attccaccca taatactgct
    19621 cggctaggat tctggctgat ccgccgataa agctgcccga catgatgatg cagactgtcg
    19681 aggctgccag catcttcttc attgtttttc tcatgtttct ctcctttgag tttagaaata
    19741 gtcattccca aacctttctt ctccgtagaa tagcttaaca tggtgagtct aagctgtgaa
    19801 tcattttctg ataattggcg tccgtagttt cgtttttttt ttaattaaaa cgtaaattgt
    19861 ctgatattat tttgggttag caaaaccagt ctaaagctgg aaaaatagta ttgaggccaa
    19921 acaataggga atgcaaaaaa gctaatcgtt cggagtaaaa cgattagctt ttttgtcatc
    19981 tagttgatag ccaatgatta aaaggctatg ggtagtgttt tagttattgc tttcttttgc
    20041 gtctagttag gaagcctaat ccgagaagag agagtaagcc tgttcccaat actgtgatca
    20101 agctgcctgt gtcatttgtt tttggcagtg atttgccgct agattggcta gtaatggttg
    20161 atggcttggt tggtttttga ggtttagctt ctgactgagg cgcaggttta ggttgaggtt
    20221 ttgtctctgg ttgaggtgta ggcttaggtt ctggtttagg gtccattggc ttaggtgcag
    20281 ggtcaggcat tggatgtggc attggatctg gggtaggagt aggattttct ccacgaggtc
    20341 cttgttcccc gcgttcgcct tgaggccctt gctccccgcg ttcgccttga ggtccttgct
    20401 ccccgcgttc gccttgaggt ccttgctccc cgcgttcgcc ttgaggtcct tgctccccgc
    20461 gttcgccttg aggtccttgc tccccacgtt cgccttgagg tccttgctcc ccacgttcgc
    20521 ctttttctcc atcttttcca ggatcaccct taggaccagg aatgccttgt tgcccagggt
    20581 ctcctttttc acctttaggc ccaggctgcc cgtccttacc atcttgtccg tctttaccag
    20641 gatccccttt gggaccagga atgccttgtt gcccagggtc ccctttttca cccttaggcc
    20701 caggctgccc gtccttacca tcttgtccgt ctttaccagg gtcccctttg ggaccaggaa
    20761 tgccttgttg cccagggtcc cctttttcac ccttaggccc aggttgccca tctttaccat
    20821 tttctccatc ttttccagga tcacccttag gcccaggctg cccgtcttta ccattttgtc
    20881 cgtcacgtcc aggagcacca tcttttcctg tatcgccttt aggacccttt tcaccaggct
    20941 taccgtctag acctttttca cctttaggcc cacgttctcc ggtttctcct ttgtcacctc
    21001 taggtccctg tggtccagta tcacctttag ggccgcgctc gcctctttca cctggtttgc
    21061 catctagtcc atcacgtcca ggtttaccag gatctccttt ttccccacgt ggaccatcta
    21121 gaccatgttt gataaatatt ctgtcaatct cttcgtttaa atccttatca tatcttccat
    21181 ttttattctt gtcattataa gtaataatcc agtagccgtt gttatatcct tgtcgcccag
    21241 cttcaaatgt taatttatag cactgacaat tttctttgta tggtatatca ggaaccggag
    21301 atttagaaat taaatgtgtg ccaagaagat tttgatatcc atatttttta taaccaccag
    21361 atttataaat gtataaatct aatgtctgtt ttttatttaa ttccgctttt tcgcctatgg
    21421 ttattagttc aaataatttt tgttcttctg tttcagtcaa accataattg gtacggaaac
    21481 tttctttagg gtaactatca gtaaaatacc atatggctaa ttgagtgact ttccttgctg
    21541 aagaatctga taagccaaga ttagaattag gatatccctt gcttaaaaga gaaaccaaag
    21601 tttttgtaat ttctgggaca gtatttctaa aatttgaagc attgctttta aatgtattat
    21661 catctcctga gattctatca tatactggta aaccattatg tatactcgaa acattatgaa
    21721 atcgttcttc ccaaggatct gggtaaaatt ttgttttgtt aaagcaataa actacacgtt
    21781 gcttactcaa atctctaact gaattaattg caggtgttac atatagaaat gaaggatttt
    21841 catgttttcc atcttcccac ccataatatt cctccgccaa cactctggct gatccgctga
    21901 tgaagctgcc tgacatgatg atacagagcg tcgaggctgc tagcatcttc ttcattgttt
    21961 ttctcattgt ttctctcctt tgagtttagg tataatcatt cctaaacctt tctttttcca
    22021 gacaatactt tagcacgacg cctgcgggct gtgaatagct ttctgacaat tgctctccgt
    22081 agtttcgttt tttttttttt ttaattaaaa tcgaaattgt ctgatattgt tacacatcaa
    22141 caagacttat ataaggctag aaaagcattg ttattgggag gctaatggtt cttacaactc
    22201 acgagctgta tgcacaggct gggcggttgc ttaatgatta atggtctatt cattagctca
    22261 tacaaatagg ccttactgac gttgagaatc cataagaaaa caccccatga tgagttgttt
    22321 tgtctaacca ttggggtgtg gatattaggc ttattgtgat ttatggtgtg ggcttagcga
    22381 tcatggcatg ggcgtgcgtc acaccgtatt gatctaggtt gatgcaggtc atctgatggc
    22441 tgctgcaatc gtatcggtaa agctttttgg gaaagaggaa atagtagctg cttgaggtca
    22501 tcataaagta gggagagctt gtctcctgac cggctagctc ctcaaagcga atggttcttt
    22561 cctctccggt atctagctgg tagatggtcc atgcaaagtc aggattataa tgctgatcat
    22621 tttcgatgat aagctcattg gttttggcat ggtggtaaat ggctctagga ctgttgacat
    22681 gaagcatgag gtaggacttt tgaccgctat ctaagtcata ggtcatcacc ttgttaccag
    22741 gtctaggttc tccagtttct aaaatgccat cagcagcctg agtaatgtaa agggttcgtc
    22801 cgacgttgac catgcgcaga taggcagtgc tttcgtccag atctatccga tcagtgatag
    22861 taaaggattt gtccattttc catagctcag ttttgggttg ctgactcttg atgtctacag
    22921 cactgacaag caggtacaga gcgtcatcaa tcaccagaaa ctgattgctg gcattaatgg
    22981 tgtctcggtt tgggatagac ttgtgagcct gttttttcag gtggcagtca tacttgtagc
    23041 agtcaatacg atcggcaaag acagctgttg tgtaaaagta atcaccatca gttgtagagg
    23101 tgtaggcgtc attgccatca gcatgaagaa ccttttcttc taggcttgct tgatcaatgt
    23161 gagttaacag gatcttaaga tcatttccct ctcttgtctt tgcaaaatat ccctgatttg
    23221 cctgcttaaa gctttctcgc tcaaatagct tgtgttgtgt tcgagagaca gtctcaacag
    23281 gcaccagact gtcagctttt tccataaagg tcctaacatg atccttgtca aaaatagcga
    23341 cttgataggg cttactaatc ttggagtggc aagcagatag ggaaaatcct cctaatgcta
    23401 gtatcaatat cgtcagcaat agcttataaa aataccttat catcattatt tattccaatt
    23461 cttataggta ggatggtaaa cataaaccta aagtctaaat gattaagtag cttaaaaata
    23521 aaaagaaagc gctctttgtt tataatatca caataatcaa taggaaatga ataatgattc
    23581 actaatgatt tcctataatt gcttatttta tgttttaatt tagaaaaaag ttatctgttt
    23641 tttaatacta accaaagctt ttaggcagct cagaagctga tgatagatac tgatagtagt
    23701 agagccagct atggttttct atcaatgtgt ggctttctct ttttctggac ggcagccttt
    23761 ttgatgtaaa ggcag
//
