LOCUS       NZ_JADPFA010000006     20873 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptococcus salivarius strain D43t1_170807_H4
            NODE_6_length_103300_cov_22.2313, whole genome shotgun sequence.
ACCESSION   NZ_JADPFA010000006
VERSION     NZ_JADPFA010000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus salivarius
  ORGANISM  Streptococcus salivarius
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 103300)
  AUTHORS   Aggarwala,V. and Faith,J.
  TITLE     Quantification of discrete gut bacterial strains following fecal
            transplantation for recurrent Clostridioides difficile infection
            demonstrates long-term stable engraftment in non-relapsing
            recipients
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 103300)
  AUTHORS   Aggarwala,V. and Faith,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-SEP-2020) Genetics and Genomic Sciences, Icahn School
            of Medicine at Mount Sinai, 1470 Madison Ave, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 27.95x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 10:18:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,053
            CDSs (total)                      :: 2,002
            Genes (coding)                    :: 1,964
            CDSs (with protein)               :: 1,964
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 13 of 38
            Pseudo Genes (incomplete)         :: 30 of 38
            Pseudo Genes (internal stop)      :: 9 of 38
            Pseudo Genes (multiple problems)  :: 12 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 23262
            Orig. end                         :: 44135
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADPFA010000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20873
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10873](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(52..72)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.49"
                     /tool="antismash"
     gene            268..1035
                     /locus_tag="I4U27_RS08225"
     CDS             268..1035
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947209.1"
                     /locus_tag="I4U27_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_195914765.1"
                     /transl_table=11
                     /translation="MAKQRIIAITGASGGLAQEIVKQLSPSDGIILLGRDKDKLEKCYR
                     HVENKTCLAIDLRDDKAIKEMVDYLYQRFGRIDVFINNAGYGEFKSYDNYTSQEVRDMF
                     DINTFATLTFSRLMAEKMVEQGNGHIVNIASMAGKIATANSSVYAATKFAVIGFSDALR
                     LELADKGVYVTTVNPGPIETGFFDQADPSGVYLESVKKFVLSPKYVAKKIVRILGKNKR
                     EVNLPRLLSVAHKGYTLFPRISDKLATNVFNYK"
     gene            1047..1202
                     /locus_tag="I4U27_RS08230"
     CDS             1047..1202
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990733.1"
                     /locus_tag="I4U27_RS08230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_155124018.1"
                     /transl_table=11
                     /translation="MAANIQAYLENPKQPWGQIYYDILFDQLQDIKEKRVLDFGSGFGP
                     VSNHLA"
     misc_feature    complement(1306..1322)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 27.21"
                     /tool="antismash"
     gene            1306..1710
                     /locus_tag="I4U27_RS08235"
     CDS             1306..1710
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990732.1"
                     /locus_tag="I4U27_RS08235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_195914766.1"
                     /transl_table=11
                     /translation="MLHYKKEIPAMTDLLALYSSVGWTNYTNNPTMLEEAVKASLWQLA
                     VYDKEELVAYIRLVGDGHSVIFVQDLLVRPDYQRQGIGTKLLEEALATFPNVYQRLLAT
                     NRSEKNLAFYQSLGFVELSEQACTGMIYKY"
     gene            2021..4222
                     /gene="recJ"
                     /locus_tag="I4U27_RS08240"
     CDS             2021..4222
                     /GO_function="GO:0008297 - single-stranded DNA
                     exodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990731.1"
                     /locus_tag="I4U27_RS08240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="WP_195914767.1"
                     /transl_table=11
                     /translation="MITSTYDWKINTKEPDAGFFKLAKEHGLAETAAKIAYERGITTEE
                     ALEGFLKADLSHLHDPYLLHDMDKAVARIRQAIENYEQILVYGDYDADGMTSASIVKEA
                     LEMMGAEARVYLPNRFTDGYGPNESVYKYFIEQEGISLIVTVDNGVAGNEAIAYAQEQG
                     VDVIVTDHHSMPAQLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLATALLETIPTEMLD
                     LVAIGTIADMVSLTDENRIMVKVGLEILKTTERIGLQELLRISDVDPTTISEETVGFKL
                     APQLNALGRLDDPNPAIELLTGFDDEEAQAIALEINAKNEERKEVVQNIFDEAITMVDP
                     DKPVQVLAKEGWHPGVLGIVAGRIMEQISQTVVVLNIEDGLAKGSARSLESINIFHALD
                     DHRDIFTAFGGHAGAAGMTLPEENLGRLSEILCHYVYDNDIDTSAKNTLNLDEELQLSE
                     LSLDTIKSLEKLAPFGMDNKKPVFWLHDITVTQARTMGQNGAHLKFKVKQGKDSFDVVA
                     FNKGHLLQEFQQAQGLELAVTLSVNVWNGQTTLQLMLEDARVDGVQLFDFRSKNMALPE
                     GLPTVEEASDTEPAVVLNTLPDSATEVKEWFEGKDFQAIYFKNSIKQAYYLTGYGTREQ
                     FARLYKTIYQFPEFDVRYKLDDLSHYLKIDKILLIKMIQIFDELDFVTIDNGVMTVNKE
                     AEKREIEDSKIFQDLKHLVKFQELMALGTPQEIYDWLYK"
     gene            4343..4861
                     /locus_tag="I4U27_RS08245"
     CDS             4343..4861
                     /EC_number="2.4.2.7"
                     /GO_function="GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006168 - adenine salvage [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /locus_tag="I4U27_RS08245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="WP_002890753.1"
                     /transl_table=11
                     /translation="MKLEDYIASIENYPKEGVTFRDISPLMADGNAYSYAIREIVQYAT
                     DKKIDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLCMH
                     ADAIKPGQRVLIVDDLLATGGTVKATIEMIERLGGVVAGCAFLIELDGLNGRKAIEGYD
                     TKVLMNFPG"
     gene            5034..5978
                     /gene="metA"
                     /locus_tag="I4U27_RS08250"
     CDS             5034..5978
                     /EC_number="2.3.1.46"
                     /GO_function="GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226132.1"
                     /locus_tag="I4U27_RS08250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="homoserine O-succinyltransferase"
                     /protein_id="WP_021144305.1"
                     /transl_table=11
                     /translation="MPIKLDNKLPALDVLRSENVFIMDENRASSQDIRPMEVLILNLMP
                     TKEVTETQLLRLLANTPLQINVEFLYMASHKSKNTHAEHMETFYKTFDEIKHKYYDGLI
                     VTGAPVEQMPFEEVDYWQELTQVFDWSKKHVYSTLHLCWGAQAGLYYKHGVDKVPLSEK
                     LSGIYKQTVDMPANFLMNGFDDSFVSPHSRYTEVRFEDIKNKTDLDIVVSGPEVGLSIL
                     ASKNLREVYSFGHFEYDRDTLAREYRRDLDAGINPDVPANYFPEDDPSQEPKLRWNLAA
                     SAFFSNWINYAVYQETPYRLEELEDDFSFYGYL"
     gene            6050..6748
                     /locus_tag="I4U27_RS08255"
     CDS             6050..6748
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990729.1"
                     /locus_tag="I4U27_RS08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DnaD domain-containing protein"
                     /protein_id="WP_195914768.1"
                     /transl_table=11
                     /translation="MSFFEQYRSGNLVLPNALFFHFKDIFPSADDFLVWQFLYLQTTTQ
                     IGEVASSQIAQATGKTPTEVNKSITTLTEAGLLDFTTIKINNEIEMVVDASPALAVLDK
                     LVSNEKTTARPVVGQPTNTQLIKQLTDELEQALGILNPMVVEDLNKEIQEEHTDPELIR
                     EALKEAVFNRKTNWNYIKGVLRNWKLSGITTKIQVEERRLEHQGKKHHHQVSDDFKTGM
                     DAARQLWGGQ"
     gene            6748..7392
                     /gene="nth"
                     /locus_tag="I4U27_RS08260"
     CDS             6748..7392
                     /GO_function="GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="nth"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990728.1"
                     /locus_tag="I4U27_RS08260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="endonuclease III"
                     /protein_id="WP_021144303.1"
                     /transl_table=11
                     /translation="MLGRKRVNEALALMGEMFPNAHGELEWETPFQLLVAVILSAQTTD
                     KAVNKITPGLWARYPEIEDLASANLDDVEMCLRTIGLYKNKAKNIIKTARAVLMNFDGQ
                     VPKTHKELESLPGVGRKTANVVLAEVYGIPSIAVDTHVSRVSKRLNIAPEDASVEEIEA
                     ELMKKIPKKDWIISHHRMIFFGRYHCLAKNPKCQTCPLQSYCKYYKETTKK"
     gene            7520..8281
                     /locus_tag="I4U27_RS08265"
     CDS             7520..8281
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884107.1"
                     /locus_tag="I4U27_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002890759.1"
                     /transl_table=11
                     /translation="MAEFSNEEYLRALADNGDREAAKEYEQALDNRIFQLQISLAQTSD
                     PQGRREVQKLLEQEEKKKRDYFQEKEEKAVSEFRRRKNETTKGRKVSSFDKLKDPKNIR
                     WVIGVVAVLAVVIPVVTLMWYSNNQKESETNPWKNGQLAKSKEAAAASSDNQSSQVDTS
                     SLSDQQLEDWVVSTYAKEQGSTGENYKNLGWNVYSWTDDDDNLVYAQLYDAYGNDVLLF
                     RVDKKGQLEAYGGIDGSSDSWDVVSKTYTTD"
     gene            8468..9796
                     /gene="xseA"
                     /locus_tag="I4U27_RS08270"
     CDS             8468..9796
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004182655.1"
                     /locus_tag="I4U27_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_195914769.1"
                     /transl_table=11
                     /translation="MSDYLSVTSLTKYLKMKFDRDPYLERVYLTGQVSNFRRRPSHQYF
                     SLKDEGAVIQATIWAGVFKKLGFELEEGMKINVVGRVQIYEPSGSYSIIIEKAEPDGIG
                     ALAIQFEQLRKKLTAEGYFDDRHKQALPNFVKKIGVVTSPSGAVIRDIITTVSRRFPGV
                     EILLFPTKVQGEGAAQEIADNIQKANQRDDLDLLIVGRGGGSIEDLWAFNEEIVVQSIF
                     GSRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPVSKADTLVWIRERQNRAYQA
                     CLRRIQYNQERLAKLSQSVVFRQPERLYDGYLQKLDRLTTRLETFVSQDFERKQKKAEL
                     LKQRLQGLNLLSSVQNYQDRRESLQRLLVTTTKNTINGNRVRLEKVQDALLSLDTSRIV
                     ARGYAIVKKDDKPLTSTKNITEGDQLTVQMRDGELEVEVKNVN"
     gene            9786..10001
                     /locus_tag="I4U27_RS08275"
     CDS             9786..10001
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /locus_tag="I4U27_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_195914770.1"
                     /transl_table=11
                     /translation="MSTKKTFEENLQDLEAIVTKLETGDVALEDAIAEFQKGMALSKDL
                     QKTLEDAEKTLVKVMQVDGTETEMDA"
     gene            10001..10873
                     /locus_tag="I4U27_RS08280"
     CDS             10001..10873
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681253.1"
                     /locus_tag="I4U27_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_195914771.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-53, bitscore:
                     174.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLNKIDAAIRDYYQKKNLPVSSDLITAILYSVDSGGKRIRPLI
                     FLDLLEGFGLELTPSHFDVAASLEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFDEAT
                     AILAGDSLFLDPFDLLAQTELSAEIRVQLIQALSHSSGTFGMVGGQMLDMKGEGQELDL
                     SQLAKIHEHKTGMLLTFPFVAAGIVAQKNLEVLENLKEAGRLIGLAFQVRDDILDVTAD
                     FEELGKTPGKDVVAGKSTYPALLGLEKSHAILEESLNKAEAIFQKLAETQGFKKDSIIE
                     IIERLRLHA"
     gene            10866..11693
                     /locus_tag="I4U27_RS08285"
     CDS             10866..11693
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014634322.1"
                     /locus_tag="I4U27_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_195914772.1"
                     /transl_table=11
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVNVINGERYDKPGE
                     KIDDGTELKLKGEKLKYVSRGGLKLEKALEVFNLSVKGMTTIDIGASTGGFTDVMLQNG
                     AKLVYAVDVGTNQLVWKLRQDERVRSMEQYNFRYAEPIDFTEGLPSFASIDVSFISLNL
                     ILPALAKILVDGGQVVALVKPQFEAGREQIGKNGIVRESSVHEKVLETVTAFALDYGFS
                     VKGLDFSPIQGGHGNIEFLAHLEKTNSPQNDAQTSIKEVVAQAHKEFKKNEEE"
     gene            11680..12126
                     /locus_tag="I4U27_RS08290"
     CDS             11680..12126
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990723.1"
                     /locus_tag="I4U27_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ArgR family transcriptional regulator"
                     /protein_id="WP_195914773.1"
                     /transl_table=11
                     /translation="MKKNDRLELIRKIVQENKITTQGELVKLLQNEGLKATQATVSRDI
                     NEIGITKVPTEDGSYIYGLSTAPRRVGGTSIATRRLLRVDRQHAFMNIVVQPGTSRLIK
                     KILLDEYKHLIFSVIADDDTLFLVAQSELAAIELQGQIIKWVEE"
     gene            12135..13805
                     /gene="recN"
                     /locus_tag="I4U27_RS08295"
     CDS             12135..13805
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227293.1"
                     /locus_tag="I4U27_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecN"
                     /protein_id="WP_195914774.1"
                     /transl_table=11
                     /translation="MLLEITIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNLM
                     LGARASSEVVRHSASKAEIQGFFSIEQNPALVSILEDNGIPVEDELIIRREIFQNGRSV
                     SRINGQMVNLTTLKAVGHFLVDIHGQHDQEELMKPALHITMLDAFGDKEFFQTKKEYQE
                     YFDRYRELRKAVLEKQKNEQDHKARIEMLAFQIAEIEAVSLKSGEDLALMQERDKLLNH
                     KQIADTLTNAYVMLDNEDFSSLSNVRSAMNDLQSLEEYDSDYKELSGNLSEAYYVLEDV
                     TKQLGDFLDNLDFDAGRLQEIEHRLDTINATTRKYGGTVDDVLDYLENSSKEYNLLTGN
                     SSSSDAMEQELKQLEKDLLASAETLQTARHQIATALEAEIKNELCDLYMDKADFKVTFT
                     KGKFNRDGNEQVEFYISTNPGEGFKPLVKVASGGELSRLMLAIKSAFARKEDKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGSHGQVLAISHLPQVIAIADYQFFISKESDNETTVSRV
                     RLLTPEERVQEIAKMLAGDNVTEAALSQARALLKVDDSL"
     gene            13875..14717
                     /locus_tag="I4U27_RS08300"
     CDS             13875..14717
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /locus_tag="I4U27_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegV family protein"
                     /protein_id="WP_070575105.1"
                     /transl_table=11
                     /translation="MSKIRIVTDSSITIEPELVKKFNITVVPLSVMVDGVIYSDSDLRE
                     EGRFLEMMKHSKELPKTSQPPVGLFAETYENLVKEGAEQIVAIHIMHTLSGTCEASRQG
                     ASLSGADVTVIDSGFTDQCLKFQVVEAAKLAEAGASLDEIVAHVEEVKNKSELHIGVST
                     LENLVKGGRIGRVTGLLSSLLNIRVIMELKDYQLNTVAKGRGAKTFTKWLDSYINGIKD
                     KDLKVAEIGISYAGTPDLAHELAEKLEVLGAPISILETGSIIQTHTGEGAFAVMVRYE"
     gene            14710..15585
                     /locus_tag="I4U27_RS08305"
     CDS             14710..15585
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096981.1"
                     /locus_tag="I4U27_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_070575108.1"
                     /transl_table=11
                     /translation="MNKWKESELVRSLVGFFLLFLLFVGLFIFIVPSTHQSSKIAEKIK
                     SIKNENVTYVAIGDSLTQGVGDSSNQGGFVPVLSQALESDFDWQVTSRNYGIAGNTSNQ
                     ILKRMQEKKDIQRDLKKAKVMTLTVGGNDVIHVIKDNITNLNVATFTKPAQAYQKRLGQ
                     IIELARKENKTLPIYIVGIYNPFYLNFPEMTEMQTIVDNWNQSTEEVCKEYDNVYFVPV
                     NDLLYKGIDGKGGVTSSDDTYQSSKSSQDSLNDALFEDDHFHPNNTGYQIMSDAILKRI
                     NQTKKEWSGE"
     gene            15578..16150
                     /locus_tag="I4U27_RS08310"
     CDS             15578..16150
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226122.1"
                     /locus_tag="I4U27_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YpmS family protein"
                     /protein_id="WP_070575111.1"
                     /transl_table=11
                     /translation="MSKIWKWLFLGLLALNLALVSVVTYRIMTPVETTSSVSLPKGATK
                     IGKYSMTKDELDAALTGFAQDYSTDKMRFKVKVTNSKIVFESSYKVLGHPVPLYVYFTP
                     VVSESGAIVLHVSELSAGTLKLPVSDALKMIKRSTNLPDYIAIDSKKGKVTLNIQSMKN
                     EKGIIARAQSLDLVNDRIEFDIYKTIN"
     gene            16287..16562
                     /locus_tag="I4U27_RS08315"
     CDS             16287..16562
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="I4U27_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_002884048.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFASIEEFLAAGEKVQL
                     IGFGNFEVRERAARQGRNPQTGEAISIAASKVPAFKAGKALKDAVK"
     gene            16622..16822
                     /locus_tag="I4U27_RS08320"
     CDS             16622..16822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002890779.1"
                     /locus_tag="I4U27_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002890779.1"
                     /transl_table=11
                     /translation="MKTITVVLIFLLVFTVIKLSGIVAISKLMKPSEEQIEEARQKRLQ
                     AEKEGKDPFEDWDERDDDGLV"
     gene            complement(16884..17819)
                     /locus_tag="I4U27_RS08325"
     CDS             complement(16884..17819)
                     /EC_number="1.3.98.1"
                     /GO_function="GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /locus_tag="I4U27_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroorotate oxidase"
                     /protein_id="WP_060971492.1"
                     /transl_table=11
                     /translation="MVSTATKVGQFTFDNCLMNAAGVHCMTKEELAEVEASAAGSFVTK
                     TGTLEARPGNPEPRYVNVPLGSINSMGLPNNGFEYYLDYVIELQKQPNTKNHFLSLVGL
                     SPEETHTILKKVQESDYEGLVELNLSCPNVPGKPQIAYDFETTTEILTEVFSYFTKPLG
                     VKLPPYFDIVHFDQAAAVFNQFPLVFVNCVNSIGNGLYIEDESVVIKPKNGFGGIGGDY
                     IKPTALANVHAFYQRLKPEIQIIGTGGVKSGRDAFEHILCGASMVQVGTALQKEGVAIF
                     DRITKELKEIMEEKGYETLEDFRGKLHYID"
     gene            18075..18767
                     /locus_tag="I4U27_RS08330"
     CDS             18075..18767
                     /EC_number="5.4.2.12"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /locus_tag="I4U27_RS08330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglycerate mutase"
                     /protein_id="WP_195914775.1"
                     /transl_table=11
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKE
                     AGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQ
                     FGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFW
                     EDKIAPALKDGKNVFVGAHGNSIRALVKHIKQLSDDEIMDVEIPNFPPLVFEFDEKLNV
                     VAEYYLGK"
     gene            complement(18866..19195)
                     /locus_tag="I4U27_RS08335"
     CDS             complement(18866..19195)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732430.1"
                     /locus_tag="I4U27_RS08335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002890783.1"
                     /transl_table=11
                     /translation="MVTKVSEYGICPFATTQRVLTGKWALVIIYQLSTGTKRFNELQRL
                     IPGITQTILTRHLRQLEKDKIVERKVYAEVPPRVEYSLTEMGRKFQGVLDAIESWGLEY
                     IETLD"
     misc_feature    19251..19267
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.75"
                     /tool="antismash"
     gene            19341..19730
                     /locus_tag="I4U27_RS08340"
     CDS             19341..19730
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106206.1"
                     /locus_tag="I4U27_RS08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_002890784.1"
                     /sec_met_domain="PF07366 (E-value: 1.7e-12, bitscore: 39.7,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVNLEIFNAYNNGLITGDFPAVFETMADDIIWHQPGQHSNSGTV
                     VGKEALGAHLAQFSEKTNGTFKVLTNWVSENIDLVAANVTFVGTRPDGEELNMNGIDLF
                     RMDDGKIKEVWLFSSDQAVEDAFWG"
     gene            <19770..>20066
                     /locus_tag="I4U27_RS08345"
                     /pseudo=""
     CDS             19770..>20066
                     /GO_function="GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /locus_tag="I4U27_RS08345"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDRDDEHSAHTDRRYALLVDSVIPDAENLKVTLERALPFWEDKIA
                     PALKDGKNVFVGAHGNSIRALVKHIKQLSDDEIMDVEIPNFPPLVFEFDEKLNV"
     assembly_gap    20067..20164
                     /estimated_length=98
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <20165..20270
                     /locus_tag="I4U27_RS08350"
                     /pseudo=""
     CDS             <20167..20270
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /locus_tag="I4U27_RS08350"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phosphoglycerate mutase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SDDEIMDVEIPNFPPLVFEFDEKLNVVNEYYLGK"
     misc_feature    complement(20202..20217)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 20.43"
                     /tool="antismash"
     misc_feature    complement(20328..20341)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
ORIGIN
        1 tgccagtgtt cgtcttggct tgggagcaga tgtcttggtg cacgagtcta cttatggtaa
       61 aggtgacgaa aaaattgcca agagccatgg gcattcaacc aacatgcaag cagcacaggt
      121 cgctaaagat gcgtcagcta aacgtcttct tctaaatcac gtatcagcac gtttcttagg
      181 gcgtgatatc ggtaagatgg cagcagatgc taaaacaatt ttcgaaaaca cccacatcgt
      241 tcgtgaccta gaagaggtag agatttaatg gctaaacaac gtattatcgc tattactggt
      301 gcctcaggtg ggcttgcaca agaaattgtc aagcagctct cacccagtga tggcattatc
      361 ctcttaggaa gagacaagga taaacttgag aaatgttatc gccatgtgga aaataaaact
      421 tgccttgcca ttgacctaag agacgacaag gccattaaag aaatggtcga ttatctctat
      481 caacgatttg gacgtattga tgtctttatc aataatgctg gttacggtga attcaagtct
      541 tatgataact acactagcca agaagtacgt gatatgtttg atatcaatac ctttgcaacg
      601 ttgacctttt cacgtttgat ggctgagaaa atggtggaac agggcaatgg gcatatcgtt
      661 aatattgcta gtatggcggg aaaaattgcg acagccaact caagtgttta tgcagcgaca
      721 aagtttgcgg taattggctt ctcagatgcc ctgcgtctag agcttgctga taaaggagtc
      781 tatgtgacaa cagtcaatcc tggtccaatt gagacaggtt tctttgatca agctgatccc
      841 tctggagtct atcttgagag tgttaaaaag tttgtcctca gtcctaaata cgtggctaaa
      901 aagattgtcc gtattctggg caaaaataaa cgtgaagtta atctaccacg actcttatca
      961 gttgcccaca aaggctacac gctatttcca cgaatctcgg acaaactagc taccaatgtg
     1021 tttaactaca aataggagga tactagatgg ccgcaaatat tcaagcgtat ttagagaatc
     1081 ccaagcaacc ctggggtcaa atctattatg atattctttt tgaccaatta caggacatca
     1141 aggagaagcg agttcttgat tttggcagtg gctttggccc tgtgtccaac cacctagcgt
     1201 aagataatag agtcctagct gtgaaaccca atgaggaaat ggtggccttg cggtcccaga
     1261 atcaccccta tcagcaacta gtcggaagtt tggaaaggag ttaagatgtt acattataaa
     1321 aaagagattc cagcgatgac agacctactc gcactgtaca gttcagtcgg ctggaccaat
     1381 tatactaaca atccaaccat gctagaagaa gctgtcaaag ccagtctctg gcagttggca
     1441 gtctatgata aggaagagtt agtagcctac attcgcttag taggagatgg tcattctgtc
     1501 atttttgtac aggacctctt ggtgcgacca gattaccagc gccaaggcat tggcacgaaa
     1561 ctcttagaag aggctttagc gactttcccc aatgtctatc aacggctcct tgccactaat
     1621 cgtagcgaga aaaatttagc cttttaccaa tccttgggat ttgtcgaact ttcagagcaa
     1681 gcttgtacag ggatgattta taaatattga tgtagaggat ttccaaatag ggaatctttt
     1741 tcttgttttt cctaatatta cttgaaaatg atagtagaat agagttagtt aacgtaaaga
     1801 ggataaagga atatctgaga aaacacaagt caaaaaggga gcaatatcca gactattatt
     1861 ttgtctagaa aagcaggtct tgattggaaa tgtaccacaa gtctaagcaa cttacgatgt
     1921 ttgacattct ctttttagga aacttagctt tctatccact atgataaatt ttttcatgtt
     1981 ataatagata gactagatga cagggagaaa agataaaaac atgattacat caacgtatga
     2041 ttggaaaata aacacaaaag agccagatgc tggctttttt aaacttgcca aagaacatgg
     2101 gctggcagaa actgcagcca agattgccta tgaacgaggc attacgacag aagaggctct
     2161 tgaaggcttt ctaaaggctg atttatcaca ccttcatgat ccttatcttc ttcatgatat
     2221 ggataaggcg gtggctagaa ttcgtcaggc tattgaaaat tatgagcaaa tcttagtcta
     2281 tggagactat gatgcggatg ggatgacgtc agcatcgatt gtcaaggaag ctcttgaaat
     2341 gatgggagct gaggctcgag tttatttgcc taaccgtttc acagatggtt atgggccaaa
     2401 tgaaagtgtc tacaagtact ttattgagca ggaaggcatt tcactcattg ttacagtgga
     2461 taatggggta gcggggaatg aggctatcgc ttatgcgcaa gagcaaggtg tggacgttat
     2521 cgttacagac catcacagta tgccggccca gcttccagat gcttatgcca ttgtccatcc
     2581 agagcatcca gatgccgatt atccttttaa gtatttggca ggttgtggtg tagctttcaa
     2641 attggcaact gccctccttg aaactattcc tactgagatg ttggacttgg tagccattgg
     2701 taccattgcc gatatggtta gcctaacgga tgaaaatcgt attatggtca aggtcggcct
     2761 ggaaattctc aagactactg agcgtattgg gcttcaagaa ttgctccgca tttcagatgt
     2821 agacccaaca acgatttctg aagaaacggt cggtttcaaa ttggcccctc aactcaatgc
     2881 cttggggcgc ttagatgatc caaatccagc cattgaactg ctgaccggat ttgacgatga
     2941 agaggcccaa gccattgctc tggaaatcaa tgctaaaaat gaagaacgta aggaagttgt
     3001 tcaaaacatc tttgatgaag ccataaccat ggtagacccg gacaaacctg ttcaggttct
     3061 ggccaaggaa ggctggcatc ctggcgttct aggtattgtg gcggggcgta tcatggaaca
     3121 aattagtcag acagtggtgg ttttgaatat tgaagatggc ttggctaagg gttccgctcg
     3181 tagtttggaa tctatcaata tcttccatgc ccttgatgac caccgagaca tctttactgc
     3241 ttttggagga catgctggag cagcggggat gacacttcct gaagaaaatc ttggacgact
     3301 atcagagatt ttgtgtcatt atgtctacga taatgacatt gatacgagtg ccaaaaatac
     3361 gttaaattta gacgaggagc tccaactcag tgagcttagc ttggatacca ttaagagcct
     3421 agaaaaacta gcaccttttg gcatggataa taaaaagcca gtcttttggc tacatgatat
     3481 taccgttact caagctagga ctatgggaca aaacggagcc catcttaagt ttaaggttaa
     3541 gcaaggaaag gatagttttg atgttgtggc ctttaataaa ggtcatttgc ttcaagaatt
     3601 tcaacaagct caggggttgg aattagcagt gaccctgtcc gttaatgtat ggaatggtca
     3661 gacaacgctc cagctcatgc tagaagatgc gcgtgtggat ggtgttcaat tatttgattt
     3721 tcgctcaaaa aacatggcac tgcctgaagg cctaccaacg gtagaagaag catcagacac
     3781 tgaacctgcg gttgtcctca acaccttacc tgattcagcg acagaagtaa aagagtggtt
     3841 tgaaggtaag gatttccaag cgatatactt taagaatagc atcaaacagg cctattatct
     3901 gaccggctat ggaacgagag agcagttcgc aaggctttat aagaccatct accaatttcc
     3961 agaatttgat gtccgctata aactagatga cctcagtcat taccttaaaa ttgataaaat
     4021 tctccttatc aagatgattc agatttttga tgaattggat tttgtgacta ttgataatgg
     4081 tgttatgaca gtcaataaag aagctgaaaa acgtgagatt gaggacagca agattttcca
     4141 agatcttaaa catctcgtca agttccaaga acttatggct ttagggacac cacaggaaat
     4201 ttatgattgg ctttataagt agggggagta cttaatccaa aggattcgtc ttgaaatgag
     4261 ggttagcatt ttctaaatct gaagattcat gctataatgg tatgtaaata tttttttggc
     4321 gaaaagccta taggaagaac aaatgaaatt agaagattat attgcatcta ttgaaaacta
     4381 ccctaaagaa ggggttactt tccgtgatat tagtcctttg atggctgatg gaaatgctta
     4441 tagctatgct atccgtgaaa tcgttcagta tgcgactgat aagaagattg acatgattgt
     4501 tggtcctgaa gcgcgtggtt tcatcgttgg ttgtccagtt gcttttgaac ttggtattgg
     4561 ttttgctcca gttcgtaaac ctggtaaatt gccacgtgaa gtgatttcag cagattacga
     4621 aaaagagtac ggtgtcgata cactgtgtat gcatgctgat gcaatcaaac caggtcaacg
     4681 tgtacttatc gttgatgatc tcttggcgac tggtggtacc gtcaaagcta caattgaaat
     4741 gattgagcgc ctaggcggtg ttgttgctgg ctgtgccttc ttgattgagc ttgatggtct
     4801 taatggacgc aaagctattg aaggttacga tactaaagta ttgatgaact tcccaggata
     4861 aatctatcta tgaattaaca aaaggcctta gggccttttt aactctttta aaatataagt
     4921 gttctctaag tatagtttaa agctatagct aactagagaa aatatatatt tgataacaat
     4981 acctccccgg tttataatat gaagatagaa taaataagga tggagatatt gttatgccta
     5041 taaaacttga taataagttg ccagctcttg atgtattgcg ttcggaaaat gtcttcatca
     5101 tggatgagaa cagagctagt agccaggata ttcgaccaat ggaggtctta atcctaaatc
     5161 ttatgccaac taaagaagtt acagaaactc agttactacg tcttttagct aatacgccac
     5221 ttcaaattaa cgtcgagttt ctttatatgg ctagtcataa gtcaaaaaat acacatgccg
     5281 aacatatgga aactttctat aagacttttg atgaaattaa gcataagtat tatgatggtc
     5341 tcattgtaac aggtgcacct gttgaacaaa tgccatttga ggaagtggat tattggcaag
     5401 aattaacaca agtttttgat tggtctaaaa agcatgttta ttcaactctc catctgtgtt
     5461 ggggagctca agcaggtctc tattataagc atggagtcga caaggttcca ttgtcagaga
     5521 aattatctgg tatctataaa caaacggttg acatgcctgc aaacttcctt atgaatggct
     5581 ttgatgatag ctttgtgtca ccgcactcac gctatactga ggttaggttc gaggatatta
     5641 aaaacaagac ggatttagat attgttgtgt caggaccaga agttggctta tccattctag
     5701 caagtaagaa tcttcgtgaa gtatatagtt ttggtcattt tgaatatgac cgtgatactc
     5761 tggcaagaga ataccgaaga gatttagatg caggcattaa tccagatgta ccggcaaact
     5821 atttcccaga ggatgatcca agtcaggagc ctaaacttcg ttggaatctt gcggcatctg
     5881 ctttctttag caattggatt aactatgcgg tatatcaaga aacaccttat cgtttagaag
     5941 agttggaaga tgatttttca ttctacggtt atttgtagta gacagtctca aaggacttat
     6001 gtgagagcat ttgacttttt ggggtgtcta gctactctga aaggtaaata tgagtttttt
     6061 tgaacagtat cgatcaggta atctggtcct tcctaatgct ttatttttcc actttaagga
     6121 tattttccca tctgcggatg actttctggt ttggcagttt ctctatctac aaacgacaac
     6181 tcagattgga gaagtggctt ctagtcagat cgcgcaagca actgggaaga cgccaactga
     6241 agttaataaa agtattacga cattgactga ggctggactt cttgatttca cgactattaa
     6301 gattaacaat gaaattgaga tggttgtaga tgcctcacct gccttggcag tattggacaa
     6361 gttagtgagc aatgaaaaga caacggcaag gcctgttgtt ggtcagccaa caaataccca
     6421 gctcatcaag caattaaccg atgaattgga acaagctttg ggaatcttga atcctatggt
     6481 tgttgaagat ttaaacaagg aaatccaaga agaacatact gatcccgaac ttatccgtga
     6541 ggctttgaaa gaagcagtat ttaaccgcaa gacaaattgg aattatataa aaggagttct
     6601 tcgtaactgg aaattaagtg gtattacaac taaaattcaa gttgaagagc gtcgtttgga
     6661 gcatcaaggt aagaagcacc atcatcaggt ttccgatgac ttcaaaacag gaatggatgc
     6721 cgcccgtcaa ttatggggtg gccaataatg ttaggaagaa aacgtgttaa tgaggctcta
     6781 gctctcatgg gagagatgtt tcccaatgct catggagagt tggagtggga aacgcctttc
     6841 cagctattag ttgctgttat tttatcagcc cagacaacag ataaggctgt taataagatt
     6901 acaccaggct tgtgggcgcg ttatccagaa attgaggatt tggcttctgc caacctcgat
     6961 gatgttgaga tgtgtttgcg aacgattggt ctttacaaga ataaagcaaa gaacatcatc
     7021 aagactgcta gagctgtttt aatgaatttt gatggacagg ttccgaaaac gcataaggaa
     7081 ttggaaagtc tacctggtgt gggacgaaaa acggctaatg tggttttagc tgaggtttat
     7141 ggcattcctt cgattgcagt agatacgcac gtctcacgtg tttctaaaag gctaaatatc
     7201 gccccagagg atgctagtgt agaggaaatc gaagcagaat tgatgaagaa aatcccaaag
     7261 aaggattgga ttatcagcca tcaccgtatg attttctttg gacgctatca ttgcctagct
     7321 aagaatccta aatgccagac ctgtcctctt caaagttatt gtaagtatta taaagaaaca
     7381 actaagaaat aagctgaaga atgtgatttt cttcggcttt ttacaactgt aagaatttgt
     7441 tacaaactag taacttgaca aaagtctcag gctttaagaa aatagaagaa acgatttaga
     7501 agcaggagcg atttagtgaa tggctgaatt cagtaatgaa gagtatctga gagccttagc
     7561 tgataatggt gatagagaag cagccaaaga atatgagcaa gctttggata atcgtatttt
     7621 tcagttgcag atttcattgg ctcaaacgag tgatccacag ggtcgtaggg aagtgcaaaa
     7681 gctcttggaa caagaggaaa agaaaaaaag ggactacttt caagaaaaag aggaaaaagc
     7741 tgtgagcgaa tttagacgtc gtaaaaatga aactacaaag ggaagaaaag tttcgagttt
     7801 tgacaaactc aaagatccta aaaacattag atgggtaatt ggagttgttg cagtacttgc
     7861 agtggttatt cctgttgtta ccttgatgtg gtatagtaat aaccaaaaag agagtgaaac
     7921 aaatccatgg aaaaacggtc agttggcaaa aagtaaggaa gcagctgcag catcatctga
     7981 taatcaatcc tctcaagttg atacctcatc tttgtctgat caacagttag aagactgggt
     8041 tgtttccacc tatgctaaag aacaaggttc aactggagaa aattataaaa atctaggttg
     8101 gaatgtttat tcatggacgg atgatgatga taacctagtt tatgctcaac tttatgatgc
     8161 ctatggtaat gatgttcttc ttttccgtgt agataagaaa ggacaactcg aagcttatgg
     8221 tggtattgac ggttcaagcg attcttggga cgtcgtctca aaaacttata caaccgatta
     8281 atgaagctat ataaaacacc tgactatggt ggttgagact gtcttttgac agtctttttt
     8341 ggtataattt aaggtaatcg tgtatacaat taaaaagctg actgagaaga tttggggatg
     8401 atggttctac agaacttttt taatgtcttc aggttttcga ggataggtta aataaaggag
     8461 agttgtcgtg tcagactatt tatcggtcac atccttaacc aaatatttga aaatgaaatt
     8521 tgaccgtgat ccttatttag agagggtata tttgacggga caggtttcca attttcgtcg
     8581 ccgcccgagt catcaatatt tttcgcttaa ggatgaagga gctgttattc aggcgacgat
     8641 ttgggctgga gttttcaaaa aacttggttt tgaactcgaa gaagggatga aaatcaatgt
     8701 cgtaggtcgt gtccagattt atgagcctag tggctcttat tccattatta tcgagaaggc
     8761 tgagccggat ggtattggag ctttggctat ccagtttgaa cagcttcgta aaaaattgac
     8821 tgcagaaggc tactttgatg atcgtcataa gcaagcgctg cctaattttg tcaaaaaaat
     8881 cggggttgtc acaagtccta gtggtgcggt tattcgagat attattacga ccgttagtcg
     8941 tcgttttcca ggggtagaaa tcttactttt ccctaccaag gttcaaggtg aaggagctgc
     9001 gcaggaaatt gctgataata ttcaaaaagc caatcaaagg gatgacttag atttacttat
     9061 cgttggtcgt ggtggaggtt ctattgaaga cctctgggct tttaacgagg aaattgttgt
     9121 tcagtccatt tttgggagtc gtctacctgt gatttcaagt gttggtcacg aaacagatac
     9181 gactttggct gactttgttg cagatcgtag ggctgctaca cctacagcag cggcagaact
     9241 tgctactcca gtatcaaagg ccgatacctt ggtttggatt cgtgaaagac aaaatagagc
     9301 ttatcaagcc tgtttgagac gtatacagta caatcaagaa cgtttagcta aactgtcaca
     9361 atctgttgtc tttaggcaac ctgagcgcct atatgatggt tatttacaaa agttggatcg
     9421 actaacaaca aggcttgaaa ccttcgtgag tcaagatttc gagcgaaagc aaaaaaaagc
     9481 ggaacttttg aaacaacggt tacaaggctt aaatcttctg agcagtgttc agaactatca
     9541 agaccgtcga gagtctttgc aacgtttatt ggtgaccaca accaagaaca ccattaatgg
     9601 taaccgtgtg agattagaaa aggtacagga tgctttattg tctctagata ctagccgtat
     9661 tgttgcaagg ggctatgcca ttgtcaaaaa agatgataaa cctttaacca gtaccaagaa
     9721 tattaccgaa ggtgatcaat taaccgtcca aatgagagat ggagaactag aagtagaggt
     9781 aaaaaatgtc aactaaaaaa acatttgagg aaaatttaca ggacttagaa gccattgtca
     9841 ctaagctcga aacaggtgat gttgctcttg aggatgctat tgctgagttc caaaaaggta
     9901 tggccttgtc taaggatttg cagaagacct tggaagatgc tgaaaaaaca ctagttaagg
     9961 ttatgcaagt agatggtaca gaaacggaaa tggatgccta atgagcaagc taaataaaat
    10021 tgatgcggct atccgtgatt actaccaaaa aaagaatctt cctgtatcaa gtgatttaat
    10081 cactgctatt ctttattcag ttgatagtgg cggtaagcgt attcgtccac tgattttctt
    10141 agatttactt gaaggatttg gtttagagct aactcctagt catttcgatg ttgcagcgag
    10201 tcttgaaatg attcatactg gaagtctgat tcacgatgat ctgccggcta tggatgatga
    10261 tgattaccgt cgaggacgtt taaccaacca taagaaattt gatgaagcaa cggcgatatt
    10321 ggctggcgat tctctctttt tggatccctt tgatctcctg gcccaaacag agctatcagc
    10381 agaaattcga gttcaattga ttcaagcatt gtctcattcc tcaggcacct tcggtatggt
    10441 tggtggccag atgttggata tgaaggggga aggtcaggaa ctagatttat cgcaactagc
    10501 taaaattcat gagcataaga caggtatgct tttaaccttt ccttttgtgg cggctggtat
    10561 tgttgctcaa aaaaatctag aggttttgga aaatctgaaa gaagctggtc gcctgattgg
    10621 tcttgccttt caagtccgtg atgatatttt ggatgtgact gctgatttcg aagaacttgg
    10681 aaagacacct ggaaaagatg tagtagcggg aaaatcaacc tatccggctc ttcttggtct
    10741 ggaaaagtca catgctatcc tcgaggaatc actcaataaa gctgaggcta ttttccaaaa
    10801 actagctgag actcaaggtt tcaagaaaga cagtattata gaaatcatag aaaggttacg
    10861 actccatgcc taaggaaaga gtagacgtct tggcttataa acaaggcctt tttgaaacac
    10921 gagaacaagc aaaacgtggc gtaatggcag gtttagttgt taatgttatc aatggtgagc
    10981 gttacgataa acctggtgaa aaaatcgacg acggtacaga gttgaagctt aaaggagaaa
    11041 aactcaagta tgtgagccgt ggaggactca aacttgaaaa agctttggaa gtattcaatc
    11101 tgtcagttaa aggcatgacg accatcgata tcggagcttc aacaggtggg tttaccgatg
    11161 ttatgcttca aaatggggct aaactggttt atgctgtgga tgtcggcact aatcagttgg
    11221 tttggaaatt gcgccaagat gagcgtgttc gttccatgga gcaatataat ttccgttatg
    11281 ctgaacctat tgattttaca gaaggactac cgtcttttgc atcaatcgat gtcagtttca
    11341 tctcgctaaa tttgattctg ccggccttgg ctaagatatt ggttgatgga gggcaagttg
    11401 ttgctcttgt gaaaccccaa tttgaggcgg gccgtgaaca aattgggaaa aacgggattg
    11461 tccgtgagag cagtgtccat gaaaaagtgc tagaaacagt gacagctttt gcgcttgact
    11521 atggcttttc agttaaagga ctggactttt cacctatcca aggtggtcat ggtaacattg
    11581 agtttctcgc acacttggag aagacaaatt ctcctcaaaa tgatgctcaa acctctatta
    11641 aggaagttgt agcacaagca cataaggagt ttaaaaagaa tgaagaagaa tgatcgtttg
    11701 gagttaatcc gaaagattgt ccaagaaaat aaaattacga ctcaaggaga attggtaaaa
    11761 ttactccaaa atgagggatt aaaggctact caagcgactg tatcgcgtga tatcaatgaa
    11821 attggtatta ccaaagtacc aactgaagac ggttcttaca tctatgggct ctcaactgct
    11881 cctagacgag taggtggaac ctctattgcg actcgtcgct tgttgcgcgt tgatcgtcaa
    11941 catgccttta tgaatatcgt tgttcaacct gggacaagcc gcctcatcaa gaagattctt
    12001 ttagatgagt acaagcattt gatttttagt gttattgctg atgatgatac cctcttttta
    12061 gtggctcagt cagagttagc agctattgaa ctacaggggc aaatcattaa gtgggttgaa
    12121 gaataggagg gcctatgctt ctcgaaatta cgataaagaa tttcgcaatt attgaagaga
    12181 tttctctaaa ctttgagaat ggtatgaccg tccttactgg tgaaacaggt gctggtaagt
    12241 ccattattat agatgctatg aatcttatgt tgggtgctag ggcttctagt gaggttgtcc
    12301 gtcattcagc atctaaggct gaaattcagg gcttcttttc aatcgaacaa aatcctgcct
    12361 tggttagtat cttggaagat aatgggattc ctgttgagga tgaattgatt atccgtcgtg
    12421 aaatcttcca aaatggtaga agtgttagtc gcatcaatgg gcagatggtc aatttaacga
    12481 cgcttaaggc tgttgggcac ttcttggtag atatccatgg acaacatgac caggaagagc
    12541 ttatgaaacc tgctctgcat attaccatgc ttgatgcctt tggtgacaag gaatttttcc
    12601 agactaagaa agagtaccag gagtattttg accgctatcg tgagttaaga aaagctgttc
    12661 ttgaaaagca gaaaaatgag caggatcata aggctcgaat tgaaatgtta gcatttcaga
    12721 ttgcagaaat tgaagcagtc tctctaaaat caggagaaga tttggctttg atgcaggagc
    12781 gagacaagct tcttaatcat aagcagattg ctgatacctt aacaaatgcc tatgttatgc
    12841 tggataatga agatttttca agcctttcaa atgtccgttc tgccatgaat gacctccagt
    12901 ctcttgaaga gtatgactct gattacaaag aactctctgg aaatctatca gaagcctatt
    12961 atgttctgga agatgtcact aagcaactag gtgatttttt ggataatctg gactttgatg
    13021 ctgggcgttt acaagagatt gaacaccgct tagataccat taatgccact actcgtaaat
    13081 atggtgggac tgtcgatgac gtcttggatt atctggaaaa ttcaagtaaa gaatacaatc
    13141 ttctgacagg aaactctagc tcgtcagatg ctatggaaca agagcttaag caacttgaaa
    13201 aggacctgct tgcgtctgcg gagaccctac aaacagcacg ccatcaaatt gctacggctc
    13261 ttgaagctga gattaagaac gagttatgcg acctctatat ggataaggct gattttaaag
    13321 tcacctttac taaggggaaa tttaatcgag atggtaatga gcaggttgag ttttacatct
    13381 caaccaatcc aggtgaaggc tttaaaccgc ttgttaaggt agcttcaggt ggtgaattat
    13441 ctcgactcat gttagcgatt aagtcagcct ttgcccgcaa agaagataaa acaagtatcg
    13501 tctttgatga ggttgacact ggcgtttcag gacgtgttgc ccaggccatc gctcagaaga
    13561 ttcataagat tgggagtcat ggtcaggtct tggccatcag tcaccttccg caagttattg
    13621 ctattgctga ttatcagttc tttatttcta aggaaagcga taacgagaca actgtctctc
    13681 gtgttcgtct tttgacacct gaggaaaggg tgcaagaaat cgctaagatg ttagcaggtg
    13741 ataacgtgac ggaggctgcc ttgagccaag caagagcttt gttaaaggtg gacgactctc
    13801 tttaggaaaa gacttgggaa aaactttcca gtcatgctat aatagaataa aaatttgtgt
    13861 taagcgagaa aaatatgagt aaaatcagaa ttgtaaccga ttcgtcaatc acgattgaac
    13921 cagaattggt taaaaaattt aatatcactg ttgtcccatt gtcggtaatg gtggacggtg
    13981 tcatctattc agatagtgac cttcgagaag aaggccgttt cttggaaatg atgaagcata
    14041 gtaaagagtt accaaagaca agccaaccac ctgtaggttt gtttgctgag acatatgaaa
    14101 atcttgtcaa agaaggtgca gaacaaattg tggcaatcca cattatgcac acactctctg
    14161 ggacatgtga agcctcacgt caaggagcta gtctttcagg agcagatgta actgtcatcg
    14221 attcaggctt tacggatcaa tgcctcaagt ttcaagttgt tgaggcagct aaattagccg
    14281 aagcaggagc tagtcttgat gagattgtag cccatgttga agaagtgaaa aataaatcag
    14341 aacttcatat tggtgtttct acccttgaga atctggttaa aggtggtcgt attggacgtg
    14401 taacaggtct actgtcttca ttactcaata tccgtgtcat catggagttg aaagactatc
    14461 agttgaatac ggttgctaag gggcgaggag ctaagacttt cacgaaatgg ttagattctt
    14521 atattaatgg tatcaaggat aaggacctca aagtggcaga gattggtatt tcttatgcag
    14581 ggacacctga tctagcacat gaactggctg aaaaacttga ggttttgggt gctccaattt
    14641 caatccttga gactggttcc atcattcaaa cgcacactgg tgaaggcgcc tttgccgtaa
    14701 tggttcgtta tgaataagtg gaaagaatca gaattagtta gaagcctcgt aggcttcttc
    14761 ttgctttttc tcttatttgt cggactcttc atttttatcg ttcctagtac gcatcagtca
    14821 tcaaaaattg cagaaaagat taaatctatc aaaaatgaaa atgtgaccta tgttgctatt
    14881 ggtgattccc ttactcaagg ggtaggtgat agtagtaatc aaggaggatt cgttcctgtg
    14941 ctatcacagg cattagagtc agattttgac tggcaagtga cttctcgtaa ctacggtatt
    15001 gcggggaata cgagtaatca aattctcaaa agaatgcaag aaaagaagga tattcaaaga
    15061 gatctcaaaa aggctaaagt gatgactctg acagttggtg gtaatgatgt gatccatgtc
    15121 attaaggaca atatcacgaa tcttaatgta gctaccttca ctaagcctgc ccaggcctat
    15181 caaaagagat taggacagat tattgagcta gctcgcaagg aaaataaaac attaccaatt
    15241 tatattgttg gtatttacaa tcctttttat ctaaattttc cagagatgac agaaatgcaa
    15301 actattgtag ataattggaa ccagtctact gaagaggtgt gcaaagagta cgataatgtg
    15361 tattttgttc ctgtaaatga tttgctttat aagggaattg atggtaaggg cggtgttaca
    15421 agttctgatg atacctatca gtctagtaaa tcttctcaag atagcctgaa cgatgctctt
    15481 tttgaggatg atcattttca tccaaataat acaggttatc aaattatgtc agatgccatt
    15541 ttgaaacgta ttaaccaaac aaagaaggag tggtcaggtg agtaagatat ggaagtggct
    15601 atttttagga ctcttggcct taaatctagc cctagtaagt gttgtgacat atagaatcat
    15661 gactccagtg gagacgacaa gttctgtatc cctacccaag ggagcaacta aaattggaaa
    15721 atatagtatg actaaggatg agcttgacgc tgctcttaca ggctttgccc aggattattc
    15781 gactgataag atgcgtttca aggtcaaggt taccaattct aaaatcgttt ttgaaagtag
    15841 ctataaggtt ttaggtcatc ctgttcctct atatgtctat tttacgccgg ttgttagtga
    15901 atcaggagca attgtactgc atgtttctga gctttcagct ggaaccttga aactgcctgt
    15961 ttcggatgcc cttaagatga ttaaacgttc gactaacctt cctgattaca tcgcaatcga
    16021 tagtaagaag ggaaaggtca ccctaaatat tcagtctatg aagaatgaga aggggataat
    16081 agcacgtgct caaagcctag atttggttaa tgaccgtatc gaatttgaca tctataagac
    16141 aataaattaa aaagccttta ctttttgcaa aaaagcgatt aaattagcgt ttattacttg
    16201 acctcatagg tcttttagga taagataata cttgttcaag cgctaaaaaa actattcgct
    16261 tagaaataaa ttggaggatt gttacaatgg ctaacaaaca agatttgatc gctaaagttg
    16321 cagaagcaac tgagcttact aaaaaagatt cagcagcagc tgtagatgca gttttcgctt
    16381 ctatcgaaga atttcttgct gcaggtgaaa aagtacaatt gattggtttc ggtaactttg
    16441 aagtacgcga acgcgctgct cgtcaaggtc gtaacccaca aactggtgaa gctatctcaa
    16501 tcgcagcttc taaagttcct gcatttaaag ctggtaaagc tcttaaagac gcagttaaat
    16561 aatgtaaaaa cccctaagat tttaggggtt ttgatttata cgaaataagt taaggaaatc
    16621 tatgaaaacc ataacagtgg tattgatttt tcttttggtt tttactgtta ttaaactatc
    16681 aggtattgtt gctattagca aactgatgaa gccaagtgaa gaacaaattg aagaagcgcg
    16741 tcagaaacgt cttcaagctg aaaaagaggg caaggaccct tttgaagact gggatgaacg
    16801 cgatgatgat ggtcttgtct aataagagaa tcatcatcaa ataacaaaaa agtttggaaa
    16861 atcttccaaa ctttttttat agactagtcg atgtagtgaa gttttcctcg gaagtcttca
    16921 agagtttcgt aacctttttc ttccatgatt tctttaagtt ctttagtaat acggtcaaaa
    16981 atagcgacac cttctttttg aagggcagta ccaacttgta ccatacttgc gccacaaagg
    17041 atgtgttcaa aagcatcacg accagatttt acaccaccag taccaataat ttggatttca
    17101 ggtttcaaac gttggtagaa agcatgaacg tttgccaagg cagtaggttt gatgtagtca
    17161 ccacctatac caccaaaacc attcttaggt ttgatgacaa cagactcatc ttcaatgtaa
    17221 aggccattac caattgagtt cacacagtta acaaagacaa gtgggaattg gttgaaaacg
    17281 gcagcagctt gatcaaagtg cacaatatca aagtatggtg gtaatttcac accaagtggt
    17341 ttcgtaaagt aagaaaagac ttcagttagg atctcggttg ttgtttcaaa atcgtaagcg
    17401 atttgaggtt tacccggaac gttaggacat gaaaggttga gttcaaccag cccttcatag
    17461 tcactttctt gaactttttt aagaatggtg tgtgtttcct caggtgaaag accaacgaga
    17521 gaaagaaaat gattttttgt attgggttgc ttttgtaatt caatgacata gtcaaggtag
    17581 tattcgaaac cgttatttgg caatcccatt gagttgattg acccaagagg tacattcaca
    17641 taacgtggtt caggattgcc gggacgggcc tcaagtgttc ctgtttttgt gacaaatgaa
    17701 cctgcagctg aagcctcaac ctctgccaat tcttccttag tcatacaatg aacaccagcg
    17761 gcattcataa gacagttatc aaacgtaaac tgaccaactt ttgtagcagt agaaaccata
    17821 agatcctcct taaagatcac aaagtaaaat gttactattt catctcattt tagcatgaaa
    17881 aggggcctaa aacaaggaaa tattggacgg gctaaagcct ctaaaacgaa attctgatat
    17941 cgtctctttt tgccaagaca agaagcaata gaattttaca gaattttttg gattttgcta
    18001 gctttttcaa ggttttttgg gtagaataga tacagtaaat gggtttaacc caaaataaaa
    18061 aggagacata actaatggta aaattggttt tcgctcgcca cggtgagtct gaatggaaca
    18121 aagctaacct tttcacaggt tgggctgacg tagatctttc tgaaaaaggt actcaacaag
    18181 ctatcgacgc tggtaaattg attaaagaag ctggtatcga atttgaccaa gcatacactt
    18241 cagtattgaa acgtgcgatc aaaacaacta acttggctct tgaagcatct gaccaacttt
    18301 gggttccagt tgaaaaatca tggcgcttga acgaacgtca ctacggtggt ttgactggta
    18361 aaaacaaagc agaagctgct gagcaatttg gtgatgagca agttcacatc tggcgtcgtt
    18421 catacgatgt attgcctcca aacatggatc gtgatgatga gcactcagca cacactgacc
    18481 gtcgttacgc ttcacttgat gactcagtaa ttccagatgc tgaaaacttg aaagttactt
    18541 tggaacgtgc ccttccattc tgggaagata aaatcgctcc agctcttaaa gatggtaaaa
    18601 acgtattcgt aggtgcacac ggtaactcaa ttcgtgccct tgtaaaacac atcaaacaat
    18661 tgtcagatga cgaaatcatg gatgttgaaa ttccaaactt cccaccattg gtattcgaat
    18721 ttgacgaaaa attgaacgta gttgctgaat actaccttgg aaaataatta taaaagataa
    18781 aaggcggaat ttattccgcc tttttttttg agaagtgact ctcggttcgt ctcactttgt
    18841 aaggtgagat gaaccgagga gataattagt ctagggtttc gatatactcc agtccccaac
    18901 tttcaatggc atctaggaca ccttgaaatt ttctacccat ttcagttaga ctgtattcga
    18961 ctcgtggggg aacttcagca tagactttac gctccacgat tttatccttc tcgagctgtc
    19021 tgaggtgtcg tgttagaatg gtttgggtaa tgccaggaat tagacgttgt agttcattaa
    19081 aacgcttagt ccccgtactg agttgataga tgatgactag agcccatttg cctgttagta
    19141 cacgctgcgt cgtggcaaaa ggacaaattc cgtattcact gactttggtt accataattc
    19201 ctccaaattt tttaaaatta ttctcttatt tgacaataat agtatcgtat ttgatactag
    19261 ataacaataa agtgcctact tgtctttttg ttagtaagtg ataatattat atcataaata
    19321 aaagaaacga ggagtaactc atgtcagtaa atttagaaat ttttaatgca tataacaatg
    19381 gtcttataac aggtgatttt ccagctgttt ttgagactat ggcagatgat attatctggc
    19441 accagccagg tcagcatagt aattccggta cagttgttgg aaaagaagca cttggagcac
    19501 acttggctca attttcagaa aaaacaaacg gtaccttcaa agtattgact aactgggtgt
    19561 ctgaaaatat tgatcttgta gcagccaatg tgacctttgt cggaactcgc ccagacggcg
    19621 aggaactcaa catgaatggt attgatcttt ttcgcatgga tgatggaaag atcaaggaag
    19681 tttggctctt ttcatcagat caagcagtag aagatgcttt ctggggttag acagtaaatt
    19741 aatctataat ctgaaatgaa atttgattta tggatcgtga tgatgagcac tcagcacaca
    19801 ccgaccgtcg ttacgcttta cttgttgact cagtaattcc agatgctgaa aacttgaaag
    19861 ttactttgga acgtgccctt ccattctggg aagataaaat cgctccagct cttaaagatg
    19921 gtaaaaacgt attcgtaggt gcacacggta actcaatccg tgcccttgta aaacacatca
    19981 aacaattgtc agatgacgaa atcatggatg ttgaaattcc aaacttccca ccattggtat
    20041 tcgaatttga cgaaaaattg aacgttnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20161 nnnngtcaga tgacgaaatc atggatgttg aaattccaaa cttcccacca ttggtattcg
    20221 aatttgacga aaaattgaac gttgttaacg aatactacct cggaaaataa gctgagataa
    20281 gtagttatca ttaacaaata gaaagttgac ttcggtcagc ttttttcttt tcttgaaaaa
    20341 taaatgtaaa aagtggtcag aaaagtcagt caattcagta atttttcctt gactttcaag
    20401 ttggaaagat gtatcatatt aaccaagata catcgaaagg aaatgagtca aatgacattc
    20461 gcaactacaa ctgttttgct attgcgtaat gagggctagt gcaaaagcat tagtcctgtt
    20521 tggcttacca agcgggaggt aaaaacatct cgcttgggtt tccgagtgag atgttttttt
    20581 actactatcg tttttacttt tagaaagagg attgtctatg cgtaaagttg aattttttga
    20641 tacaagtctt cgtgatgggg aacaaacacc aggtgttaac ttttcaatca aagaaaaagt
    20701 tgccattgct aagcaacttg aaaaatgggg gatttctgta atcgaagcag gttttcctgc
    20761 agctagccca gattcatttg aggcagtaaa acaaattgcg gaagctatga caacaacttc
    20821 tgttactggt ttggctcgtt cagtaaaatc tgatattgat gcttgttatg agg
//
