LOCUS       NZ_JADPFA010000001     41167 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptococcus salivarius strain D43t1_170807_H4
            NODE_1_length_499016_cov_26.3491, whole genome shotgun sequence.
ACCESSION   NZ_JADPFA010000001
VERSION     NZ_JADPFA010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus salivarius
  ORGANISM  Streptococcus salivarius
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499016)
  AUTHORS   Aggarwala,V. and Faith,J.
  TITLE     Quantification of discrete gut bacterial strains following fecal
            transplantation for recurrent Clostridioides difficile infection
            demonstrates long-term stable engraftment in non-relapsing
            recipients
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 499016)
  AUTHORS   Aggarwala,V. and Faith,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-SEP-2020) Genetics and Genomic Sciences, Icahn School
            of Medicine at Mount Sinai, 1470 Madison Ave, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 27.95x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 10:18:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,053
            CDSs (total)                      :: 2,002
            Genes (coding)                    :: 1,964
            CDSs (with protein)               :: 1,964
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 13 of 38
            Pseudo Genes (incomplete)         :: 30 of 38
            Pseudo Genes (internal stop)      :: 9 of 38
            Pseudo Genes (multiple problems)  :: 12 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:50:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 212922
            Orig. end                         :: 254089
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADPFA010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41167
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="2"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41167
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41167
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21167](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21167)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            346..3006
                     /gene="mgtA"
                     /locus_tag="I4U27_RS01020"
     CDS             346..3006
                     /EC_number="7.2.2.14"
                     /GO_function="GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mgtA"
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894669.1"
                     /locus_tag="I4U27_RS01020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="WP_195914467.1"
                     /transl_table=11
                     /translation="MSTNKERLIAALQEPLETTLTRYKTHLDGLKEDQVEENRDLYGEN
                     VITKGQEDSIIKKIYESIINPFTVILLVIALVSFITNVWLAKPGEEDPTTSIIIVTLVL
                     ISGGIRFIQELRSDKAASNLSRMIVNTATVLRDGSEQEIPIDEIVVGDVVKLSAGDMIP
                     ADVVLLDSRDFFVQQSGLTGESDAVEKACLAKADGQNLESLLESESLAFMGTNVISGRA
                     TALVLVVGDETMMGAIEQTINTYDEPTSFEREMNSISWLLIRLMLVMVPVVFVINGLTD
                     GDWLEAGVFALSVGVGLTPEMLPMIITASLAKGSIIMAKEKVVIKKLNAIQDLGAIDIL
                     CTDKTGTLTQDEIVLEYPLDIHGDLDLSVLRRAYLNSYFQTGLKNLMDRAIISRTEREA
                     KKHEIVRDLDQTFHKIDELPFDFERRRMSVIVKDNDGFVSMVTKGALEEMLSVSNYVEY
                     KGDIIPLTDDVREEVLAEVAQLNEQGLRVLGVSYKSQLNENDVFSVEDESDMILTGYLA
                     FLDPPKPSAAPAIKALAEYGVTTKILTGDNDKVTQAVCEKVGLDVTHILLGSDLDTMSD
                     QDLAKAVETTTVFAKLSPDQKARIILSLKENGHKVGYMGDGINDAPSMKVSDVGISVDT
                     AVDIAKETADVILLDKDLMVLEKGLVEGRKVYANMTKYIKMTVSSNFGNIFSLLFASIF
                     LPFLPMAPVHLIVLNLVYDISCIALPFDNVDKEFLKEPHIWEAKSIMRFMAWIGPISSV
                     FDILTYILLYFIIVPMILGHGYVHGSPEAAAFIIIFQTGWFIESMWSQTMVIHMLRSPK
                     LPFIQSHPALSVVVTTLFAAFFVTSLPYSPLASLLKLSHLNGLYFILLFIIITLYMLSV
                     TFVKHIYIKKYKEWL"
     gene            3291..4673
                     /gene="glmU"
                     /locus_tag="I4U27_RS01025"
     CDS             3291..4673
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA]"
                     /GO_function="GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226982.1"
                     /locus_tag="I4U27_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
                     GlmU"
                     /protein_id="WP_195914468.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.8e-21, bitscore:
                     71.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNYAIILAAGKGTRMKSDLPKVLHKVSGITMLEHVFRAVSAIEP
                     AKNVTVIGHKAELVREVLDGQSAFTMQTEQLGTGHAVMMAEEELAGLEGQTLVIAGDTP
                     LITGESLKNLIDFHVNHKNVATILTATADNPFGYGRIIRNENGEVTKIVEQKDANEFEQ
                     QVKEINTGTYVFDNKRLFEALKNINTNNAQGEYYLTDVISIFRENGEKVGAFTLRDFEE
                     SLGVNDRVALATAEDVMRRRINQAHMVNGVTFQNPNATYIDVDVEIEPDVVIEANVTLK
                     GQTKVGAESVLTNGTYIVDSTIGANTVITNSMIEHSVVEEGVTVGPFAHVRPDSTLKKD
                     VHIGNFVEVKGSTIGENTKAGHLTYIGNAEVGSDVNFGAGTITVNYDGQHKFKTQIANN
                     VFIGSNSTLIAPLEIGANALTAAGSTITDDVPADSVAIGRGRQVNKEGYAIKKPHHPSQ
                     QK"
     gene            4753..5301
                     /locus_tag="I4U27_RS01030"
     CDS             4753..5301
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265941.1"
                     /locus_tag="I4U27_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NUDIX hydrolase"
                     /protein_id="WP_002886219.1"
                     /transl_table=11
                     /translation="MDFEEKTLKRESKFKGHIFEVAVDEVLLPDGKTAGRELIFHKGAV
                     AVLAVTPEGKIIIVKQYRKAIEAVSYEIPAGKLEVGEAGDEMAAAARELEEETQYKGDL
                     ELIYEFYTAIGFCNERIKLYVATNLKPVENPRPLDDDEFLELYELTYEECMELVASGAI
                     QDAKTIIALQYYALHFGGK"
     gene            5305..5565
                     /gene="macP"
                     /locus_tag="I4U27_RS01035"
     CDS             5305..5565
                     /codon_start=1
                     /gene="macP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950108.1"
                     /locus_tag="I4U27_RS01035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cell wall synthase accessory phosphoprotein MacP"
                     /protein_id="WP_014634097.1"
                     /transl_table=11
                     /translation="MGKPLLTEDIIEQAKRGEIDLEEHPYYEDYDQEFYDEDYEADYQP
                     SAYKSRRIENAKRNQFQHKLNRILFWVVVLLILLFIAVFYF"
     gene            5632..6324
                     /locus_tag="I4U27_RS01040"
     CDS             5632..6324
                     /EC_number="3.2.2.9"
                     /GO_function="GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA]"
                     /GO_function="GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009164 - nucleoside catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621328.1"
                     /locus_tag="I4U27_RS01040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="WP_002886153.1"
                     /transl_table=11
                     /translation="MKIGIIAAMEQELVLLVEQLENKVEETVLGNTYYTGRLGKHDVVL
                     VQSGVGKVMSAMSVAVLADHFGVDALINTGSAGAVAPGLKIGDVVVASKLAYHDVDLTA
                     FGYDYGQMSMQPLYFESDSTFVETFEKVLAQASIDSKIGLIATGDSFIAGQDKIDAIKG
                     HFPEVLAVEMEGAAIAQAAHSVKKPFIVVRAMSDTAAHDANITFDEFIIQAGKQSAAIL
                     VEFLKELA"
     misc_feature    6433..6446
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.67"
                     /tool="antismash"
     misc_feature    6434..6447
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.53"
                     /tool="antismash"
     misc_feature    complement(6674..6689)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.16"
                     /tool="antismash"
     gene            6717..9743
                     /locus_tag="I4U27_RS01045"
     CDS             6717..9743
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014634098.1"
                     /locus_tag="I4U27_RS01045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FctA domain-containing protein"
                     /protein_id="WP_195914469.1"
                     /transl_table=11
                     /translation="MNNRFGDSRQRFSIRKFTVGVASVLLSSAVFGVSTAKADQAEEPK
                     GQPATSVLEEASESDGGGQRTSTSASSQEVTAEPTVQAESTSAISVTAVSSEAALQEQT
                     VASSEQTSSSQDKTSEGLSEKPVTVNETREASASDLAAANNTSSASSDNFGLKVTNLSR
                     PIPADVKVTKTGTEITVQNPDVEMEFPNGNSKYATSKVVYHNIPFPDDMTINEGDQVIF
                     NLPEQLRFRTSYDINVYNPDNQIVGLAQIDPEKNRVTTTFNNYFQTHPNNKLMSLELDT
                     LYSEEVDEGEHLTLDFEGRIIHVSVGKVQSPPPGQEVISKWGSQDKHDPTILNWQMRLN
                     YSRRLLNNLKLVDTWSDNQRFVDGSLQLRYIDSADPWIDKGSAMDLIKSFSYDDSHFEL
                     KLNQLDRMVYVWYQTRLTQPVEESANPVNRIKLHADVVSDSYKSTIRLVGGRGDAIGDN
                     LAHFNLELEKDLTGRDLKDKEFTFKLVDVTDSANPVDLGETTNDGKGKIVFSDLSLSKP
                     GIYHYRVTEVPGNDEDVVYDKLEANITIQVVRETVDNQVKLVANVAYPEDIIFNNKLVT
                     PAKAKIAFGKELTKAGVKQDLKADQFQFVLKDRFGKVLETVGNTADGQVAFSELTFNKV
                     GTYNYTVEELTGKDDSIVYDSMKAAVSITVTRDGDALVSTVVNPKDTIFNNKFVTPAKA
                     AIQFSKELTKAGVNQTLTANEFQFVLKDSAGHIVETVGNTADGRVAFSELHFDKAGTYT
                     YTVEEVKGTNEDIIYDGMKATVWITVTRDGDALVSTVANPKDTVFNNYVKDVQPAKAKF
                     ELTKVLTGRNLKDGEFSFVLKDDKGNVIQTVTNNAQGNISFENIVYDKPGVYYYTVEEV
                     KGNEADVVYDNMVAKFQVTVTKTVGEKENLLVAAVLLPLDTEFNNSYIPPKPPTPPTPP
                     TPPSVPPKPPVVPPTPPTPPTPPVTPKPAKPVQSSEKSGPQLPETGQANDTALLALGVA
                     AEVAAVMGVAYSHRRRKDV"
     gene            9874..10872
                     /locus_tag="I4U27_RS01050"
     CDS             9874..10872
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004192896.1"
                     /locus_tag="I4U27_RS01050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_004182965.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.6e-10,
                     bitscore: 35.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLLYLEGKSVLEKSGIGRALHHQMHALDLAGIPYTTDILGDYD
                     VVHINTYGPRSLMLLHAAKRRGKKVIMHGHSTREDFENSFIGSNLLAPLFGKYLAHMYQ
                     KADYVITPSEYSKKLIQSYGVTTPIIAVSNGIDLKKYGKDPRKEEVFRDYFGIEEGQPV
                     VICAGLYFQRKGIEDFVKVAEKMPHVRFIWLGSISKWLIPKKIRDIVNGKHPDNVSFPG
                     YFKGAVFQGAMSGANAFFFPSYEETEGIVVLEAFASHQHVVLRDIPVYEGWVDDKSASF
                     GHNVDEFVVALQDIIDGKVDKREEGYKVAESRSIDDVAQKLVEAYKEVLEI"
     gene            10873..12195
                     /locus_tag="I4U27_RS01055"
     CDS             10873..12195
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934263.1"
                     /locus_tag="I4U27_RS01055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_014634100.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.6e-30,
                     bitscore: 100.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTQLEKMGHTVFIFTTTDRDV
                     DRYEDWQIVRIPSVPFFAFKDRRVAYRGFSKALEIAKQYKLDIIHTQTEFSLGLLGIAI
                     ARELRIPVVHTYHTQYEDYVRYIAKGMVIRPSMVKYIVRGFMSDLDGVICPSEIVYDLL
                     LKYKVAAEKRVIPTGIELEKFQRPEITEDDVADLRAKLGIASDETMLLSLSRVSYEKNI
                     QAVLAALPSVLEEDDKVRLVVAGDGPYLPDLKSQAKKLGIQDKVVFTGMIAPSETALYY
                     KSADFFISASTSETQGLTYLEALASGTPIIAHGNPYLDNVITDQMFGTLYYHDNDLAGA
                     ILEAAIATPEKDETKWADKLYEISAENFGKRVYEYYLDLTISKDFHNDLNGEDSTMKRL
                     TRMVTYLPTKAITLPVNGSVRILKGSAKQVKKIRNITKLLD"
     gene            12654..13046
                     /locus_tag="I4U27_RS01060"
     CDS             12654..13046
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008534056.1"
                     /locus_tag="I4U27_RS01060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_195914470.1"
                     /transl_table=11
                     /translation="MGFNYEAIKAYLIDHGVDASLAETMHAIYATRRIGRSTFEYFLIV
                     FTETEVLIISLTLLGKLGDIIAKFPEETIKSYQFKKRLFIGYKLRIFLNDGRELDFNVN
                     KILIGADWHKTELQSILETNYYNKNN"
     gene            13095..15041
                     /gene="thrS"
                     /locus_tag="I4U27_RS01065"
     CDS             13095..15041
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004182963.1"
                     /locus_tag="I4U27_RS01065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_195914471.1"
                     /transl_table=11
                     /translation="MINITFPDGAVREFESGVTTFDIAQSISNSLAKKALAGKFNGKLI
                     DTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGFYY
                     DTDNEAGQISNEDLPRIEEEMKKIVKENFPSIREEVTKDEAREIFKIDPYKLELIEEHS
                     EDEGGLTIYRQGEYVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNAMMQRIYGTAW
                     FDKKDLKAYLKRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRVLERYI
                     VDKEVAAGYQHVYTPPIASVELYKTSGHWDHYREDMFPTMDMGDGEAFVLRPMNCPHHI
                     EVYKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHTFVTPEQIKDEF
                     QRTLQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYFDNDEMWENAQSMLKSAMDDMELDY
                     FEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEEHRPVMIH
                     RGVISTMERFTAILIENYKGAFPTWLAPQQVTVIPVSNEAHTDYAWEVAKQLRDRGIRV
                     EVDERNEKMQYKIRASQTQKIPYQLIVGDKEMEDGTVNVRRYGQKQTHTEAVSEFVENI
                     LADIARKSRPDAE"
     gene            15091..16029
                     /locus_tag="I4U27_RS01070"
     CDS             15091..16029
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950124.1"
                     /locus_tag="I4U27_RS01070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_195914472.1"
                     /sec_met_domain="PF00561 (E-value: 6.8e-06, bitscore: 20.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVFRKRLLFLLGAVLLLLLSSFTYHRLSLQREKASLNPMGQMVS
                     VNGHEMSIFVKGEGPQTLVFLSGAGTASPILDFKDLYDGLSKQYKIVVVERAGYGYSED
                     TSKSRDVSEVLSETRQALAKTHVSGPYIILSHSMASVETLLWQEKYPGEVKAIIGLDWA
                     LPESYSHLKMHPQILRMARWGSQLGLLRYLPKSLYVPNENLSSSDRRLYQRIAYRQILS
                     KAMLNESLSVKKNAKKVASSIDSQIPTLLMVSNGGGTGFSQKDWRHYATSFAKDQKNIE
                     VTFYDSPHYLYHYPTKEVAAKIEEFIKKTTD"
     gene            16059..17117
                     /locus_tag="I4U27_RS01075"
     CDS             16059..17117
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014634104.1"
                     /locus_tag="I4U27_RS01075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3114 domain-containing protein"
                     /protein_id="WP_195914473.1"
                     /transl_table=11
                     /translation="MLIGSKAFRHLWEDWQRDYQPLQVLKLLLAYIGMPEDLSGELEET
                     QHLLSYFDPDLAPHDSFWKDVVKLVDLAFPGDSLSKNASIERQIHQLRYLISSQQSQYV
                     RTHYKKPGMTDKEALAVYLRWKPFTMFDQGRLHQKISICDGKAVYPDGIPSVNLKILLY
                     NRIEFILDSQGNFLNEVDAEQVTESGVVNGASFNYGNFKRHWQLDVEPVQPHDPDFRNR
                     MTRGFRSPNKLKKRWGQQAPEQFDKSFYNPKGIYAQSHRSLANDVKRQARFFLALVYGF
                     KPNQTKQSKEVHMSKQPQNNKGTAVLGSLVFMALYALGIWHNAVRGNIPFLILWSVLLL
                     VNVSYFIFRLRK"
     gene            complement(17191..17382)
                     /locus_tag="I4U27_RS01080"
     CDS             complement(17191..17382)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002886147.1"
                     /locus_tag="I4U27_RS01080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PspC domain-containing protein"
                     /protein_id="WP_002886147.1"
                     /transl_table=11
                     /translation="MKKELRRDPNNKIIAGVCSGIAKYLDIDPVIIRLIWAAAIFLFGT
                     GFLFYIICWIIIPEESKW"
     gene            complement(17439..18116)
                     /locus_tag="I4U27_RS01085"
     CDS             complement(17439..18116)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002952667.1"
                     /locus_tag="I4U27_RS01085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hemolysin III family protein"
                     /protein_id="WP_002886236.1"
                     /transl_table=11
                     /translation="MSNTATFNTSPNLKLSKKLSFGEEVANSVTHAVGAVAMLVLLPIT
                     AVHANNGYGMTAAVGMSVFVISLFLMFLSSAIYHAMDYNSPHKMVLRIIDHSMIYIAIA
                     GSYTPVALSLVGGWLGYSIIILQWGTTIFGILYKIFAKKINEKFSLFLYLMMGWLVIFI
                     IPAIVTKTGPAFWGLMLAGGLSYTVGAAFYAKKKPYFHMIWHLFIMLASALQYLGIVYF
                     MLP"
     gene            complement(18109..18558)
                     /locus_tag="I4U27_RS01090"
     CDS             complement(18109..18558)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002885964.1"
                     /locus_tag="I4U27_RS01090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1836 domain-containing protein"
                     /protein_id="WP_002885964.1"
                     /transl_table=11
                     /translation="MTTQQYPLWEELPEIELYLDQVLLYVNQVTQSTLGPNDKGLTASM
                     VNNYVKHGHVAKPIKKKYNAAQVARLIVITSLKTVFEISEIAKTLEILRTDAESQKSYY
                     NDFVACMNGQFPQEAPQVILSACQTLQCYRATHQLLNDLEGGNNV"
     misc_feature    18528..18544
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.43"
                     /tool="antismash"
     gene            complement(18728..19999)
                     /locus_tag="I4U27_RS01095"
     CDS             complement(18728..19999)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003094754.1"
                     /locus_tag="I4U27_RS01095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_013990948.1"
                     /transl_table=11
                     /translation="MTKLSWTGFSKKTPQERKEHLKTNALLSQENQDLLDKDQQLTLET
                     ANQMAENVIGRFTLPFAICPDVLVDGVTYQVPMVTEEPSVVAAASYASKLIKRSGGFTT
                     TIHDRQMIGQVALFDVPDKDNASSKIQAASQDLIEIAKEAHPSIVKRGGGPRKLWTETK
                     GDFLIVYLAVDTQEAMGANMVNTMMEALVPELENLSEGQSLMAILSNLATESLVTATCR
                     LSTRFLSRNKEEAHDLAKKMEMASQLAQVDPYRAATHNKGIFNGIDALVIATGNDWRAV
                     EAGSHAYASKDGSYRGLSTWTYNQESKELVGELSLPMPIATRGGSIGLNPSASIAHDLL
                     NHPDAKTLASIIVSLGLAQNLAALKALTSTGIQAGHMKLQAKSLALLAGASPEEMPQVL
                     AELLKAKHMNQETAQAILEKLRTP"
     gene            complement(20001..21167)
                     /locus_tag="I4U27_RS01100"
     CDS             complement(20001..21167)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777082.1"
                     /locus_tag="I4U27_RS01100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_195914474.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.7e-07,
                     bitscore: 25.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIGIDKIGFATSQYVLNMADLALARGAEPEKFSKGLMLDATSIT
                     PITEDIVTLASDAAADILNDDDKNAIDMVIVATESSIDQSKAAAVYVHSLLGIQPFARS
                     FEMKEACYAATAGLNYAKLHVAAHPDSKVLVIASDIARYGVESSGESTQGAGAVAMLVS
                     QNPRILELADDNVAQTRDVMDFWRPNYSSTPYVQGIYSTKQYLDSLKTTWAAYQERHQA
                     DFADFAAFCLHLPYPKLALKGLNKIIPKDLNPENKERLTNNFDASITYSRQIGNIYTGS
                     LYLGLLSLLEQSQDLKAGDKIGFFSYGSGAVSEIFSGRLVEGYKDLLRSDRLDTFAKRQ
                     HLSVTDYEKLFYEEAQLDDTGSTQFADYQTGAFRLAEISEHQRIYKGH"
     misc_feature    complement(21597..21606)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            21638..22498
                     /locus_tag="I4U27_RS01105"
     CDS             21638..22498
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="I4U27_RS01105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thymidylate synthase"
                     /protein_id="WP_084914850.1"
                     /transl_table=11
                     /translation="MTKADTIFKENITKIMEEGVWSEQARPKYKDGTTANSKYITGAFA
                     EYDLSKGEFPITTLRPIAIKSAIKEVFWIYQDQTNSLDVLEDKYNVHYWNDWEVEGVPA
                     NNGDKRSIGQRYGAVVKKHDIINRLLAQLEANPWNRRNVISLWDYEAFEETAGLQPCAF
                     QTMFDVRRVGEDIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFI
                     NNLHIYDNQFEQAEELLKRQPSDCQPRLVLNVPDGTNFFDIKPEDFELVDYEPVKPQLK
                     FDLAI"
     misc_feature    21656..21669
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.73"
                     /tool="antismash"
     gene            22607..23110
                     /locus_tag="I4U27_RS01110"
     CDS             22607..23110
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990945.1"
                     /locus_tag="I4U27_RS01110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrofolate reductase"
                     /protein_id="WP_002885904.1"
                     /transl_table=11
                     /translation="MSKQLIAIWAEAHNHVIGKNHTMPWHLPAELAHFKKTTMGSAILM
                     GRVTFDGMNRRCLPGRETLILTRDKDFDCEGVTTVTSVEEALAWFEQQDKDLYIAGGAG
                     VYKAFDGHYDALIKTTIEADLEGDTYFPQLDMTAFKEVSRDRVAKDDKNAYDFSISRYE
                     KEGD"
     gene            23115..23285
                     /locus_tag="I4U27_RS01115"
     CDS             23115..23285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="I4U27_RS01115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002886174.1"
                     /transl_table=11
                     /translation="MQRSVFGLFTALLGVLCVLSAIPAFRKKRYGLAVFLFLNAFTNLV
                     NTIHAFYGTLF"
     gene            23303..24529
                     /gene="clpX"
                     /locus_tag="I4U27_RS01120"
     CDS             23303..24529
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680904.1"
                     /locus_tag="I4U27_RS01120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002886084.1"
                     /transl_table=11
                     /translation="MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEII
                     REEMAEEVLADLAETPKPKELLDILNNYVVGQDRAKRALAVAVYNHYKRINFTESREDN
                     DVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENILLKL
                     IQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPP
                     QGGRKHPNQEMIQIDTKNILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYM
                     QEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRILTEPRNALVKQYQTLLSYDGV
                     ELEFDQDALEAIATKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDG
                     TAAPVLETA"
     gene            24539..25138
                     /gene="yihA"
                     /locus_tag="I4U27_RS01125"
     CDS             24539..25138
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796923.1"
                     /locus_tag="I4U27_RS01125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_021144508.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNAEILLSAANKSHYPQDDLPEVALAGRSNVGKSSF
                     INTLLGRKNLARTSGKPGKTQLLNFYNIDDKLRFVDVPGYGYARVSKKERAKWGKMIEE
                     YLVTRDNLRVVVSLVDLRHEPTQDDIQMYEFLKYYEIPVIVVATKADKIPRGKWNKHES
                     IIKKKLNFDKNDHFIIFSSVTRDGYDEAWDTILAEL"
     gene            25268..26644
                     /locus_tag="I4U27_RS01130"
     CDS             25268..26644
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058615.1"
                     /locus_tag="I4U27_RS01130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid permease"
                     /protein_id="WP_002886136.1"
                     /transl_table=11
                     /translation="MENHNYENEGQFQRKMTSRHLFMLSLGGVIGTGLFLSSGYTIAQA
                     GPLGAILSYLVGAIVVYLVMLSLGELAVAMPVTGSFHTYATKFISPGTGFTVAWLYWIC
                     WTVALGTEFLGAAMLMQRWFPSVPAWMFAAFFALVIFGINALSVRSFAEAESFFSSIKV
                     IAILVFIILGLGAMFGLVSFDGHREAIMFKHLTANGLFPNGGLAIVSVMLAVNYAFSGT
                     ELIGIAAGETDNPKEAVPRAIKTTIGRLVIFFVLTIVVLASLLPMKEAGVSSAPFVDVF
                     DKMGIPFAADIMNFVILTAILSAGNSGLYASSRMLWSLANEGMLNKKLVKINKHGVPMT
                     ALLISMAGAVLSLFSSIYAADTVYLALVSIAGFAVVVVWLSIPMAQINFRKQWNLEHSD
                     DELDYKTPFNPILPYITIILLAISVLGIAWDSSQRAGLYFGIPFMIFCYLYHYLRFKKW
                     "
     misc_feature    complement(25285..25299)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.85"
                     /tool="antismash"
     gene            26656..27606
                     /gene="mmuM"
                     /locus_tag="I4U27_RS01135"
     CDS             26656..27606
                     /EC_number="2.1.1.10"
                     /GO_function="GO:0047150 - betaine-homocysteine
                     S-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mmuM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950163.1"
                     /locus_tag="I4U27_RS01135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="homocysteine S-methyltransferase"
                     /protein_id="WP_195187654.1"
                     /transl_table=11
                     /translation="MAIFKDYLENKSPLILHGALGTEMESLGYDISGKLWSAKYLLDKP
                     EVIQKIHETYVAAGSDLITTSSYQATLPGLIDAGLTKEEAEQIIALTVQLAKNARDKVW
                     ATLDDSEKANRPYPLISGDVGPYAAYLANGSEYTGDYGQIIIEALKEFHRPRIQILLDH
                     GVDLLALETIPNYLEAQALIELLAEEFPEAEAYISFTVQEPGTISDGTSLDEIAQLVGQ
                     SDQILALGINCSSPLLYNQALAILKNAGKALITYPNSGEVYDGSTQTWKPKDKDALTLV
                     EHSKDWHTQFGVKILGGCCRTRPNDIKALYAEFRT"
     gene            27719..27973
                     /locus_tag="I4U27_RS01140"
     CDS             27719..27973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004182954.1"
                     /locus_tag="I4U27_RS01140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1912 family protein"
                     /protein_id="WP_002886199.1"
                     /transl_table=11
                     /translation="MTYEQEFLKDFEAWVVTQVKVNETALAASKKIWEEDGDERARDAS
                     YRYEAKLDAYNFLIGKFANYRAGKGFHDMPDGLFGERHY"
     gene            28048..28425
                     /locus_tag="I4U27_RS01145"
     CDS             28048..28425
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950165.1"
                     /locus_tag="I4U27_RS01145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="WP_002885939.1"
                     /transl_table=11
                     /translation="MAKVKNKKKAFKHRLKKQGLFNNVKAPVPPVAPVPPVPPVAPQPV
                     AETKTVAKEEVAAKDLSLEAFAELPEVEGLRSNLVETLYNEGLTSAEAFATVTEEEVLA
                     LKGVGPATVKKLKENGVSFKA"
     gene            complement(28543..29184)
                     /gene="plsY"
                     /locus_tag="I4U27_RS01150"
     CDS             complement(28543..29184)
                     /EC_number="2.3.1.15"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0008374 - O-acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="plsY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962188.1"
                     /locus_tag="I4U27_RS01150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="WP_038675561.1"
                     /transl_table=11
                     /translation="MKILLLILIAYLLGSIQTGLWIGKLFFHTNLREHGSGNTGTTNTF
                     RVLGKTAGTITFLVDMFKGTLAVLLPIWLGVTEVSPLVIGFFAIIGHVFPIFAGFKGGK
                     AVATSAGVLLGFAPLYCVFLLLVFALTLYLTSMISFSSVTAAVVGLITLAVFPAIHFLL
                     DGYDLIFTGVLTIMALIIIFRHTENMGRICRHQENLVPFGLNLTKQNPKK"
     gene            29322..31271
                     /gene="parE"
                     /locus_tag="I4U27_RS01155"
     CDS             29322..31271
                     /EC_number="5.6.2.2"
                     /GO_component="GO:0009340 - DNA topoisomerase IV complex
                     [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="parE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632049.1"
                     /locus_tag="I4U27_RS01155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="WP_002886138.1"
                     /transl_table=11
                     /translation="MAKKEINVNNYNDDAIQVLEGLDAVRKRPGMYIGSTDGTGLHHLV
                     WEIVDNAVDEALSGFGDVIAVTLNKDGSVSVSDSGRGMPTGMHAMGKPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGSVYRQRFENGGHPVTGLEKIG
                     KAPKSKTGTKVTFMPDASIFSTTDFKFNTISERLKESAFLLKNVTMTLTDLRGEEEVRE
                     EFHYENGVQDFVSYLNEDKETLTPVIYIDGDQQEFHLELALQYNDGYSDNILSFVNNVR
                     TKDGGTHETGFKSAITKALNDYARKTGLLKEKDKNLEGSDYREGLSAVISLLVPEEHLQ
                     FEGQTKDKLGSPLARPIVDSIVSEHLTYFLMENGDLASNLVRKAIKARDAREAARKARD
                     ASRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRKFQAILPLR
                     GKVLNTEKAKMADILKNEEINTMIYTIGAGVGADFNLDDINYDKIIIMTDADTDGAHIQ
                     TLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEVVEYAWTDGELEELRQKFGRG
                     AILQRYKGLGEMNADQLWETTMDPETRTLIRVTIDDLARAERRVSVLMGDKAAPRRQWI
                     EDNVKFTLEENTVF"
     gene            31327..32145
                     /locus_tag="I4U27_RS01160"
     CDS             31327..32145
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019236.1"
                     /locus_tag="I4U27_RS01160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="WP_195914475.1"
                     /transl_table=11
                     /translation="MRTDTEMMNLILQIADTLEVEAIALSGSRTNPQATKDEFQDYDVV
                     YIVDDLEELISDLSWLDQFGNRLIEQHNRLGHRRLYVMLFEDGNRIDLTLCLKEYIQEW
                     VDSEANFEVIKDDKGLFDSYIPSPKRYWTAPPTEEEFAASCNEFWWVSAYVVKAIRRNQ
                     LIYATDHLYGICQQELLKVLAWQVTSDRGAVDIGKNYKYLFQYLPAEQEKEFSALLDLS
                     SLEKISQSLFSSMKGFDREAQILAQKMGFTYDKEVAEKMISYAKEKLSNH"
     gene            32319..34775
                     /gene="parC"
                     /locus_tag="I4U27_RS01165"
     CDS             32319..34775
                     /EC_number="5.6.2.2"
                     /GO_component="GO:0009340 - DNA topoisomerase IV complex
                     [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="parC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008534084.1"
                     /locus_tag="I4U27_RS01165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="WP_195914476.1"
                     /transl_table=11
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRIL
                     YSMNKDGNTHDKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMHGN
                     NGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKNTVPWAWNFDDTEKEPTVLPAAFPNLL
                     VNGATGISAGYATDIPPHNLSEVIDAVVYMIDHPSAKLDKLMEFLPGPDFPTGAIIQGK
                     DEIRKAYETGKGRVVVRSRTEIEQLKGGKEQIIVTEIPYDVNKAVLVKKIDDVRVNNKV
                     PGIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTDLQVNYNFNMVAIDNFTPRQV
                     GLQKILSSYIAHRRDIIVARSKFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKA
                     DAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEEADLREQIATLAAIIGDERT
                     MFNVMKRELRDIKKKFGNDRRSELQAETKTIEIDTASLIVEEETYVSITRGGYVKRTSP
                     RSFNASTIDEVGKRDDDDLILVQQAKTTQHLLIFTNQANVIYRPIHELPDIRWKDLGEH
                     LSQTITNLSKDEEVLYAEILDDFETGTYLAATKLGQIKRFERKEFTPWRTYKSKSVKYA
                     KLKDDSDFIVTVTPIQLDDIMIITQKGYALRFNADEVPVVGAKAAGVKAINLKDDDTVQ
                     AVFVANTQSFYLLTQRASLKRVATADIPQAKRAGRGLQVLRELKTKPHRVFTAGPVFTE
                     NAGGEIDLLATPVEETPQTLLVTATTGETAEVDLSLLNLSDRTSNGSFIEGLADKEVFS
                     AKSIER"
     gene            <34932..35963
                     /locus_tag="I4U27_RS01170"
                     /pseudo=""
     CDS             <34932..35963
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (75-324). E-value: 3.7e-24.
                     Score: 77.7. Matches aSDomain:
                     nrpspksdomains_I4U27_RS01170_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961903.1"
                     /locus_tag="I4U27_RS01170"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="branched-chain amino acid aminotransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="DIHMTVDLDWENLGFNYSKLPFRYISYYKDGKWDEGQLTEDATLH
                     ISEASPALHYGQEAFEGLKAYRTKDGSIQLFRPDENAKRLQRTADRLLMPQVPVDKFVD
                     ACKQVVRANEEYVPPYGTGATLYLRPLLIGVGDIIGVHPADEYIFTIFAMPVGNYFKGG
                     LAPTNFLIQDDYDRAAPHGTGAAKVGGNYAASMLPGKIAHDRNFSDVIYLDPATHTKIE
                     EVGSANFFGITADNEFVTPLSPSILPSITKFSLLYLAENRFGMKAIQGDVKISELDKFV
                     EAGACGTAAVISPIGGVQHGDDFHVFYSETEVGPITRKLYDELTGIQFGDVEAPEGWIV
                     KVD"
     aSDomain        35160..35906
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I4U27_RS01170_Aminotran_4.1"
                     /evalue="3.70E-24"
                     /label="I4U27_RS01170_Aminotran_4.1"
                     /locus_tag="I4U27_RS01170"
                     /protein_end="324"
                     /protein_start="75"
                     /score="77.7"
                     /tool="antismash"
                     /translation="FRPDENAKRLQRTADRLLMPQVPVDKFVDACKQVVRANEEYVPPY
                     GTGATLYLRPLLIGVGDIIGVHPADEYIFTIFAMPVGNYFKGGLAPTNFLIQDDYDRAA
                     PHGTGAAKVGGNYAASMLPGKIAHDRNFSDVIYLDPATHTKIEEVGSANFFGITADNEF
                     VTPLSPSILPSITKFSLLYLAENRFGMKAIQGDVKISELDKFVEAGACGTAAVISPIGG
                     VQHGDDFHVFYSETEVGPITRKLYDEL"
     gene            36082..36312
                     /locus_tag="I4U27_RS01175"
     CDS             36082..36312
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014634116.1"
                     /locus_tag="I4U27_RS01175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2969 domain-containing protein"
                     /protein_id="WP_002886057.1"
                     /transl_table=11
                     /translation="MSKKDKKIEIQINDAKVVVNKATIEGFELLVGKKVIGQIVEIDGK
                     FAVVDKENVVGFHKKMDDAVAAIIESYNLNH"
     tRNA            36373..36453
                     /anticodon=(pos:249329..249331,aa:Tyr,seq:gta)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="I4U27_RS01180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Tyr"
     gene            36373..36453
                     /locus_tag="I4U27_RS01180"
     misc_feature    36498..36507
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     tRNA            36522..36593
                     /anticodon=(pos:249476..249478,aa:Gln,seq:ttg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="I4U27_RS01185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Gln"
     gene            36522..36593
                     /locus_tag="I4U27_RS01185"
     gene            36714..37916
                     /gene="rpsA"
                     /locus_tag="I4U27_RS01190"
     CDS             36714..37916
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /locus_tag="I4U27_RS01190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S1"
                     /protein_id="WP_002885935.1"
                     /transl_table=11
                     /translation="MNEFEELLNSVSEVNTGDVVTAEVISVDNDQANVVIEGTGIEGVL
                     TRRELTNDRDANVADLVKVGETLEVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKLVG
                     REEEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEQFVGQEFDAKIKEVDP
                     AENRFILSRREVVEAEAAEARKEVFSKLEVGSIVTGKVARLTSFGAFIDLGGVDGLVHV
                     TELSHERNVSPKSVVSVGDEVEVKVLAIDEEAGRVSLSLKATTPGPWDGVEQKLAAGDV
                     IEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQDVTVKVLEVNADA
                     ERVSLSIKALEERPANAEGENNEKRQSRPRRPKRQEKRDFELPETQSGFSMADLFGDIE
                     L"
     misc_feature    36763..36775
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.57"
                     /tool="antismash"
     tRNA            37984..38055
                     /anticodon=(pos:250939..250941,aa:Arg,seq:ccg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="I4U27_RS01195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Arg"
     gene            37984..38055
                     /locus_tag="I4U27_RS01195"
     misc_feature    37994..38009
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(38265..38278)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     tmRNA           38306..38655
                     /db_xref="RFAM:RF00023"
                     /gene="ssrA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /locus_tag="I4U27_RS01200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="transfer-messenger RNA"
     gene            38306..38655
                     /gene="ssrA"
                     /locus_tag="I4U27_RS01200"
     gene            38701..39321
                     /locus_tag="I4U27_RS01205"
     CDS             38701..39321
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621341.1"
                     /locus_tag="I4U27_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3862 domain-containing protein"
                     /protein_id="WP_195914477.1"
                     /transl_table=11
                     /translation="MKKLLSLTVLGLSLFTLAACGKSSSKTETKGSLDNEASKILTVKH
                     GNVRQNFDKITMANASQEFSGGSNLDSLKGWFGEPSSTSQEQAGDAKLDVYNWQYDNVV
                     VTAKLFNNSTVVKSISNFSYVRDPKITLKMYDNLKNGTSYDDAVKTLGTPDVYSIAVSS
                     DATMTQALWSSNLVAKKGETGSLTLNFKNGALESKSQANLTNK"
     gene            39587..40087
                     /locus_tag="I4U27_RS01210"
     CDS             39587..40087
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014727379.1"
                     /locus_tag="I4U27_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VTT domain-containing protein"
                     /protein_id="WP_192831325.1"
                     /transl_table=11
                     /translation="MILSSAIPGVSSSIFCIFVGLLYGPLLAIPMNIIGNTFGNLTSFE
                     ILRRLEKPEKSKRMEKLLNYIENFKHRFIGISLAFSIPFIPSALVNYACVQMNLPTRTR
                     ILATLIGVTPVSIVYAVSGDLLLNIRPIRIPLVAVLAILLFISLVIYFIHFRKEKNELH
                     SSN"
     misc_feature    complement(40124..40135)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(40174..40194)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.24"
                     /tool="antismash"
ORIGIN
        1 cggatgacta ccgcaaagca gtggagacac tactcgttgg tcaacagtcc tgatcgccaa
       61 ggtcaagact aagctcattt catcgccttg cggagctaaa gcttgaacgg tccatttttt
      121 gacagaatct attaaaaaat caacctcgag tttatagagt cttacctgta tatgggtagg
      181 actcttttct tttgtctgag gtccacccac tatgtaaaaa aatgaaagga gaaacctatg
      241 agactaatcg acgatcaccc cgaaccgcac ctaaccagtc aatcgctgat tagtgtctta
      301 gggactccat aagtgattgg ctcctgatta aataaggaga ttccaatgtc aacaaataaa
      361 gaaagactta ttgctgctct tcaagagcca cttgaaacaa cccttactcg ctacaagact
      421 catttggatg gcttgaagga agaccaagta gaagaaaacc gtgaccttta tggggaaaat
      481 gtcataacca aaggacaaga ggattctatc atcaaaaaga tttatgaatc tatcatcaat
      541 ccctttactg ttattctctt agtcattgct ctggtttcct ttatcaccaa tgtctggctt
      601 gctaaaccgg gtgaagaaga cccaacgact tctatcatca ttgtcactct agttttgata
      661 tctggtggta tccgttttat tcaagaactt cgtagcgaca aggctgccag taatttgtct
      721 cgcatgattg tcaatacagc aacagtactt cgagatggca gtgagcaaga aatcccaatt
      781 gatgaaattg tggttggaga tgtggtcaaa ctaagtgcgg gagatatgat tccggctgat
      841 gtggtcttac tagattctcg tgatttcttt gttcaacagt ctggcttgac aggtgaaagc
      901 gatgctgtgg aaaaagcttg tctggctaaa gcagatggtc aaaatctaga gagcctgctt
      961 gaaagtgaga gccttgcttt catgggaact aatgttatct ctggtcgtgc aacagccttg
     1021 gttttagttg ttggtgatga aaccatgatg ggagcaattg agcagaccat caatacttat
     1081 gacgaaccaa cttcatttga acgtgagatg aattccattt cttggctctt gattcgactc
     1141 atgttggtta tggttcctgt tgtttttgtg attaacggtt taacagatgg ggactggctt
     1201 gaagccggcg tctttgccct tagtgtggga gtcggtttga ccccagaaat gttgccgatg
     1261 attatcacag ccagtcttgc caagggttct atcattatgg ccaaggaaaa ggtggtcatc
     1321 aaaaaactta atgctattca agacctaggg gctatcgaca tcctttgtac ggataagaca
     1381 ggaaccctga ctcaggatga aatcgttctt gagtaccctc ttgatatcca tggcgacctt
     1441 gacctttcag tgcttcggag agcctatctt aactcttatt tccaaactgg cttgaaaaat
     1501 cttatggacc gtgccattat tagtcgaact gagagagaag ctaagaaaca cgagattgtt
     1561 cgtgaccttg accaaacctt ccacaagatt gatgagctcc cttttgattt tgaacgacgt
     1621 cgcatgagtg tcattgttaa agataatgat ggttttgtca gtatggtgac aaaaggtgcc
     1681 cttgaagaaa tgctctctgt ttctaactat gtggaataca agggtgacat tatcccatta
     1741 acagacgatg ttcgtgagga agttctcgcg gaagtcgcac agttgaatga acaaggtttg
     1801 cgtgttctcg gtgttagcta taaatcacag cttaatgaga atgacgtctt tagtgtcgaa
     1861 gatgaaagtg atatgatttt gacgggatat cttgccttcc ttgacccacc aaaaccatca
     1921 gcagcacctg ctatcaaggc tttggcggaa tatggtgtga ccacaaaaat tttgactgga
     1981 gacaatgata aggtgacaca ggctgtctgt gaaaaagttg gtctagatgt gacgcacatt
     2041 ctacttggaa gtgatcttga taccatgtca gatcaagatt tggctaaggc tgtggaaacg
     2101 acaacagtct ttgctaagtt atccccagac caaaaggcac gaattatcct aagccttaag
     2161 gaaaatggcc ataaggtagg ctatatgggt gatggtatca acgatgcccc atccatgaag
     2221 gtgtcagatg tggggatttc tgtggataca gctgttgata tcgccaaaga aactgcagat
     2281 gttatcttgc ttgataagga tttaatggtc ttggaaaaag gtttggttga aggacggaag
     2341 gtctatgcta atatgaccaa atatatcaag atgaccgttt cttcaaattt cgggaatatc
     2401 ttttctctcc tctttgccag cattttctta ccattcctac caatggcacc tgtgcatttg
     2461 attgtcctaa atcttgtcta tgatatctct tgtatcgccc ttccatttga caatgtggac
     2521 aaggaatttc ttaaagagcc acatatctgg gaagccaaat caatcatgcg tttcatggct
     2581 tggataggac ctatttcgtc cgtatttgat attttgacat atatcttgct ctatttcatc
     2641 attgtgccaa tgattttggg gcatggctat gttcatggtt caccagaagc agcagccttt
     2701 atcattattt tccaaacagg ttggtttatc gaatctatgt ggtctcaaac catggttatc
     2761 cacatgttac gttcaccaaa actaccattt attcaaagtc acccagcact atcagttgtt
     2821 gtgacaacct tatttgctgc tttctttgtg acttctcttc catacagtcc attggctagt
     2881 ctcttaaaac tcagccatct aaacggtctc tatttcattc tcttgtttat catcattact
     2941 ttgtatatgc ttagtgttac ctttgtgaag catatctata ttaagaaata caaagaatgg
     3001 ttataggata actattctta gaaaaagagc gtcagctctt ttttcattac ctttcattct
     3061 gccaaaacct tttcatttat ggtataatag ggcgattata gataatcaga ggccctaaaa
     3121 aacgtctgtt atgaggacat cttttctaag aaatgagaga ctatgttttc aaggcccctt
     3181 tctttcgtag gctatcccag tgggaggttg aggtcctgag atttggggct caaggctaag
     3241 accgcctcga aggaaaccat cacaaataaa tcttaagaag gaaaaagaaa atgagtaatt
     3301 acgctattat ccttgctgcg ggtaaaggaa ctcgcatgaa atcagatctt ccaaaagtat
     3361 tgcacaaggt ttcaggcatc actatgcttg agcatgtctt ccgtgcagtt tcagctatcg
     3421 aaccagctaa aaacgttact gttattggtc acaaggctga gcttgttcgt gaggttttgg
     3481 acggtcaatc tgccttcact atgcaaactg agcagttggg gactggtcac gcagtaatga
     3541 tggctgaaga agagttggct ggacttgaag ggcaaacgct tgttatcgcc ggtgacacgc
     3601 ctttgattac cggtgaaagc cttaaaaacc ttattgattt ccatgttaat cacaaaaatg
     3661 ttgccactat cttgactgca actgcggaca atccgtttgg ttatggtcgt attatccgta
     3721 acgaaaatgg cgaagtgact aagattgttg agcaaaaaga tgccaacgag tttgaacaac
     3781 aggttaaaga aatcaataca gggacttacg tttttgataa taaacgcctc ttcgaagcac
     3841 ttaaaaatat caacaccaac aacgctcaag gggaatacta tttgactgat gttatttcta
     3901 ttttccgtga gaatggtgaa aaagtaggtg ccttcactct tcgtgacttt gaagaaagtc
     3961 tcggggttaa cgaccgtgtt gccttggcta cggcagaaga tgttatgcgt cgtcgcatca
     4021 accaagctca catggttaat ggtgttactt tccaaaatcc aaatgctact tatatcgatg
     4081 tggatgtgga aattgagcca gacgttgtca ttgaagccaa tgttacgctt aaagggcaaa
     4141 ctaaagtcgg tgcagagtca gtgcttacca atgggactta tattgttgat tcaactatcg
     4201 gtgccaatac tgttatcact aactctatga ttgagcactc agtggttgaa gaaggtgtta
     4261 ctgttggtcc atttgcccat gttcgtccag attcaaccct caaaaaagat gttcatatcg
     4321 gtaacttcgt tgaggttaag gggtctacta tcggtgaaaa taccaaagct ggtcacttga
     4381 cctacattgg taatgcggaa gttggttctg acgttaactt tggtgccgga acaattaccg
     4441 taaactatga tggacaacac aagttcaaga cacaaattgc taacaatgtc tttatcggta
     4501 gcaattcaac cttgattgca ccgcttgaaa ttggggctaa cgctctcaca gcggctggtt
     4561 caaccatcac agatgatgtg ccagctgaca gcgtagccat tggacgtggc cgtcaggtca
     4621 ataaagaagg ctatgccatt aagaaacctc accacccaag ccaacaaaag taggcttaag
     4681 gctatctgag ctagattctc ttgtagagta gatgtagctt agaatgaggt cagaagtaaa
     4741 aggagtcaat tcatggattt tgaagaaaaa acactcaaac gtgagtcaaa atttaaggga
     4801 catatttttg aagttgcagt agacgaggtc ctcttgccag acggtaagac agctggtcgt
     4861 gaactcatct tccacaaggg agcagtagct gttttagcgg ttaccccaga aggaaaaatc
     4921 attatcgtca aacaataccg caaggctatt gaggcggttt cttacgagat tcctgcgggt
     4981 aagctggaag tcggtgaagc tggcgatgag atggctgcag cggcgcgtga acttgaagag
     5041 gagactcaat acaagggtga tctggaattg atttatgaat tttacacagc cattggcttt
     5101 tgtaatgaga gaatcaagct ctatgtagcg actaacctta aacctgtgga aaatccacgt
     5161 ccacttgatg atgatgagtt ccttgaactc tatgaattga cctatgaaga gtgtatggaa
     5221 cttgtagcgt caggggctat ccaggatgcc aaaactatca tcgccctcca atactatgca
     5281 cttcatttcg gaggaaaata agctatggga aaaccacttt tgaccgaaga tatcattgag
     5341 caggccaagc gtggggaaat cgatttagag gaacatcctt attatgagga ctatgatcaa
     5401 gagttctatg acgaggatta tgaggctgat taccagcctt ctgcctacaa gagccgtcga
     5461 attgagaatg ccaaacgcaa tcaatttcaa cacaagctta atcgcatcct cttttgggta
     5521 gtggtcctct tgattcttct cttcattgct gtcttttatt tctaaaaagt ctatgagtca
     5581 gatagcccta gctactgatt caggaaagat tacaagctga aaaggaacta tatgaaaatc
     5641 ggaattatcg ctgccatgga gcaggagtta gtgcttctag tggagcaatt ggaaaataag
     5701 gttgaagaaa ctgttcttgg caatacctac tacacaggac gtttgggaaa acacgacgtc
     5761 gttttggtac aatcaggtgt tggtaaggtt atgtcagcca tgtctgtggc tgtcttggca
     5821 gaccattttg gcgttgatgc cctcattaac actggttctg caggagcagt agcacctgga
     5881 cttaaaattg gagatgtggt tgtagcttca aaattagcct atcacgatgt tgatttgaca
     5941 gcctttggct atgattatgg gcaaatgtct atgcagccac tttactttga aagtgactct
     6001 accttcgtag agactttcga aaaggtcttg gctcaggctt ccattgattc taagattggg
     6061 cttatcgcta cgggtgatag cttcattgca ggtcaagaca agattgatgc cattaagggg
     6121 cattttccag aagtcttggc tgtagagatg gagggagcag ctattgctca agccgcacac
     6181 agtgtcaaaa agcctttcat cgttgtacgt gccatgagtg atacagcggc tcatgatgct
     6241 aacattacct ttgatgaatt cattattcag gcggggaaac aatcagctgc tatcttggtt
     6301 gagtttctca aagaacttgc ctaaaataca ttaaatgagt gcttatgctc attttcttaa
     6361 ttaatttaaa gatgactgct attcatttaa gaatggcagt ttttttctgc ttttagataa
     6421 gataagcttc tcatttttta aagaaaaaat ctgaatttta gcatttttca gacggaagtt
     6481 gaattaaaat tatgacaata aaatgagaaa gaaaaataat attaaaagag agactccgaa
     6541 agaaagctta tcatataagg gtttacaaat ttcactatct attgatatct tagaaagctt
     6601 tacaaaacct ccaaaggggt aaataattat cttgcaaagt tctgaaaata gtgtataatt
     6661 cagaatgaaa agggttacaa aaatgttaag atttgtaaaa atgggaggat agaatcatga
     6721 ataaccgatt cggtgattcg cggcagcgtt tctccatccg taagtttacg gtgggcgttg
     6781 cttcggtctt actttcgtct gcagtttttg gtgtaagtac cgccaaagca gatcaagctg
     6841 aagagcctaa aggccaacca gcgacgagtg tacttgagga agccagtgag tctgatggtg
     6901 ggggccaaag gacgagcact agtgcctcaa gtcaagaagt gacagctgaa cctaccgttc
     6961 aagcagaaag taccagtgct atctcagtaa ctgctgtttc tagtgaagct gcgcttcaag
     7021 agcaaacggt tgcaagctct gagcaaacaa gttcatcaca agataagact agtgaggggc
     7081 tcagtgagaa acctgttaca gtcaatgaaa cacgagaagc tagcgctagc gaccttgctg
     7141 cagcaaacaa tacgagttcc gcttcgtcag ataatttcgg acttaaggtt accaacctaa
     7201 gtcgcccgat tccagcggat gtcaaggtga caaagacagg aactgaaatc actgttcaaa
     7261 atcctgatgt ggaaatggaa tttccgaacg gaaatagtaa gtacgctact agcaaggttg
     7321 tctaccacaa tattcctttc cctgatgata tgaccatcaa tgaaggggat caggtcattt
     7381 ttaatttgcc tgagcagttg cgattccgta ctagctacga tatcaatgtc tataatccag
     7441 acaatcaaat tgtaggtctg gctcaaattg atcctgagaa gaatcgtgtc actacgacct
     7501 ttaataacta tttccaaaca catcctaaca ataagctcat gagtttggag ttggataccc
     7561 tttattctga agaagtagat gaaggggaac atcttactct tgattttgag ggacgtatca
     7621 ttcatgtttc agtgggtaaa gtgcagtcac ctcctccagg tcaagaggtt atttctaagt
     7681 ggggtagtca agataagcat gatccaacta tcctaaattg gcagatgcgt cttaattact
     7741 cacgacgtct ccttaacaac ttgaaactgg ttgatacttg gtctgacaat caaagatttg
     7801 tggacggttc tttgcaactt cgctacattg attcggcaga tccttggatt gacaagggtt
     7861 cagctatgga tttgattaag agtttctctt atgatgatag ccattttgag cttaaactca
     7921 atcagttgga ccgcatggtt tatgtttggt atcaaacccg tttgacacaa cctgttgaag
     7981 aatcagctaa ccctgtcaac cgtattaaac ttcatgctga tgttgtttcc gattcttaca
     8041 agtcaactat tcgcttggtt ggtggccgag gagatgccat cggagataac ctcgctcatt
     8101 tcaatcttga gcttgagaag gacttgacgg gtagagacct taaggataaa gaatttacat
     8161 ttaaattagt tgatgtgact gatagtgcca atcctgttga cttaggggaa accactaatg
     8221 atggcaaggg taaaatcgtc ttttcagatc tctcactcag taagccaggt atctatcatt
     8281 atcgtgtgac agaggttcca ggtaatgacg aagatgtggt ctatgacaaa ctagaggcca
     8341 atatcaccat tcaggttgtt cgtgaaactg tggacaatca agtcaaatta gttgccaacg
     8401 ttgcctatcc agaagacatt atctttaaca ataaattggt aacaccagcc aaggccaaaa
     8461 ttgcatttgg taaggaattg accaaggcag gcgttaaaca agatctaaaa gcagatcaat
     8521 tccaatttgt tctcaaagac cgttttggaa aagtccttga aactgttggc aatacagctg
     8581 atggtcaggt tgcctttagt gagttaacct ttaacaaggt aggtacttac aactacactg
     8641 ttgaagagct tacaggtaag gatgattcaa ttgtttatga cagcatgaaa gctgctgttt
     8701 ctatcacggt aacacgtgat ggcgacgccc ttgtttcaac cgtggttaat cctaaagaca
     8761 ctatctttaa caacaagttt gtgactccag ctaaggccgc tattcagttc agtaaggaat
     8821 tgactaaggc aggtgtcaac caaactttga ctgctaatga gttccaattt gttctcaaag
     8881 atagtgccgg tcatattgtc gaaacagttg gtaatacagc tgatggtcgt gttgccttta
     8941 gtgaacttca ctttgataag gcaggaactt acacttatac tgttgaagaa gttaagggaa
     9001 ctaacgaaga tatcatctat gatggtatga aagcaactgt ctggattaca gtgacacgag
     9061 atggtgatgc tttggtatca acagttgcta atccaaaaga tactgttttc aataactatg
     9121 tgaaagacgt gcaaccagct aaggccaaat tcgaattgac caaggttctt acaggtcgta
     9181 acctcaaaga tggtgagttt agtttcgttc tcaaggacga caagggtaat gttatccaaa
     9241 cagtgaccaa taatgcacaa ggaaacatta gttttgaaaa tattgtctac gacaaaccag
     9301 gtgtttacta ctacactgtt gaagaagtca agggcaatga agctgacgtg gtttatgata
     9361 acatggtggc taaattccag gtgaccgtta ctaagactgt aggtgaaaag gaaaatctgc
     9421 tcgtagcagc cgttctcctt cctttggata cagaatttaa caatagttac attcctccaa
     9481 aacctcctac accgccaaca ccaccgacac caccaagtgt cccacctaaa ccaccagtgg
     9541 ttccgccaac accaccaact ccgcctactc caccggtgac tccaaaacca gctaagccag
     9601 ttcaatcctc tgagaaatca ggacctcaac ttccagagac tggtcaagct aacgatactg
     9661 ccttgcttgc ccttggtgtg gcagcagaag tggcagcagt catgggtgta gcatatagcc
     9721 atcgtcgccg taaagacgtt taagatgatg acctaaaaga tcgagtattc tcgatctttt
     9781 ttagtatttg gccacccatc tcattaaatg agaaatcaag ataaagccaa ctgcaagatg
     9841 aaatttctac taaattaagc tataatgaag agtatgaaag ttctacttta tcttgaagga
     9901 aaatcggttc ttgaaaaatc aggaatcgga cgggctctcc accatcagat gcatgccttg
     9961 gacttggcgg ggattcccta tacaacggac atcttgggtg attacgatgt cgttcatatt
    10021 aatacttatg ggccacgcag cttgatgttg ttgcatgctg caaaacgccg tggcaagaag
    10081 gtcatcatgc atggtcattc gacacgtgag gactttgaga attcattcat cggttctaac
    10141 cttttggccc cactttttgg gaaatatttg gcccacatgt accaaaaggc cgattacgtg
    10201 attacgccat ctgagtattc caaaaaattg attcagtctt acggagttac cacaccaatc
    10261 attgctgttt caaatgggat tgatttgaaa aaatacggta aggatccacg taaggaagaa
    10321 gttttccgag actactttgg tatcgaggaa ggacagccag tggttatttg tgcggggctt
    10381 tatttccaac gcaagggaat tgaagacttc gtcaaggtgg ccgaaaagat gcctcatgtt
    10441 cgttttattt ggttaggtag catcagcaaa tggttgattc ctaagaagat tcgagacatt
    10501 gtcaatggta agcatcctga taatgtcagc ttcccaggtt atttcaaggg agccgtcttc
    10561 cagggggcta tgagtggtgc taatgccttc tttttcccat cttacgagga aactgaaggg
    10621 attgtggtgc tagaagcctt tgctagtcac cagcatgtag ttttgcgtga tattcctgtt
    10681 tatgaaggtt gggttgatga caagtcggcc tcatttgggc acaacgtgga cgaatttgta
    10741 gtagccttgc aagatattat cgatggtaaa gtggacaaac gtgaagaagg ctataaggtt
    10801 gcagaaagtc gctcgattga tgatgtcgcc caaaagcttg ttgaagccta caaagaagta
    10861 ttggagattt aaatgcgtat cggattgttt acagatacct attttccaca ggtatcaggt
    10921 gttgcgacca gtattcgcac gctgaagacg cagttggaaa aaatgggaca tacagtcttt
    10981 atctttacca ccactgatag agatgttgac cgctatgaag actggcagat tgtccgtatt
    11041 ccgagtgtgc ctttctttgc ttttaaggat cgccgtgtag cttatcgtgg cttttccaag
    11101 gcactagaga ttgctaaaca atataagctt gatattattc atacgcagac agagttttca
    11161 ttaggtctgc tagggattgc cattgcacgc gaacttagga ttcctgttgt gcatacctac
    11221 catactcagt atgaagacta tgtccgctat attgccaaag gtatggttat ccgtccaagt
    11281 atggttaagt acattgttcg aggctttatg agtgatttgg atggagttat ctgtccgagt
    11341 gagattgttt atgacctttt gctcaagtac aaggttgcag ctgaaaaacg tgtcattcca
    11401 actggaattg agcttgaaaa attccaacgt ccagagatta ctgaagatga tgtggcggac
    11461 ttgagagcca agcttggtat tgcttctgat gagaccatgt tgttgagcct ctctcgtgtg
    11521 tcctatgaga aaaacatcca ggctgtactg gctgctctcc cttctgtttt ggaggaagac
    11581 gacaaggtac gtttggttgt agctggtgac ggtccttacc taccagatct taagtctcaa
    11641 gccaaaaaac ttggtattca ggacaaggtg gttttcactg gtatgattgc gcctagtgag
    11701 acagcacttt attataagtc tgctgatttc ttcatttcgg catcaaccag tgagactcag
    11761 ggcttgacct atctggaagc cttggctagc ggtaccccta tcattgctca cggaaatcct
    11821 tatttggata atgtgattac agaccagatg tttggaacgc tttattatca tgataatgat
    11881 ttagccgggg ccattttgga agctgccatt gcaacaccag aaaaagacga aactaagtgg
    11941 gctgacaagc tttatgaaat ttctgcggaa aactttggaa aacgtgtcta tgagtattac
    12001 ttggacctta cgatttctaa ggatttccac aacgatttga atggtgaaga cagtaccatg
    12061 aaacgcttga cgcgtatggt aacttatttg ccgactaagg ctattacctt gcctgttaac
    12121 ggctctgttc gtatcctcaa aggatcagcc aaacaggtca agaaaatcag aaatatcacg
    12181 aaacttttgg attaggaaag ccaccagatt ttcctagtca gataaaatct tagaattgat
    12241 taataaaaga gataattagc ttgaaaaatt acagtttcat gctataataa cgcatagaga
    12301 catatcagtc atgggaaatc tttcagagag cgtgtggcgc tggaaatcac gcagaggaca
    12361 tgattgggac tactcgatta actttttatg caaacataaa acggtggcca cgttagagcc
    12421 aatcagaggt gtaggacaga ctcgtttttt gtcgtacatg aactaaggtg gaaccacgtt
    12481 gcgacgtcct tttgaggatg tcgcttttta tattatttgg tatgctttac aatttttaga
    12541 atgtctagtt tagatagaaa agctttactt tgtgactaaa tattttctct ttgattacta
    12601 aaaggattgt ttagaacgag gtgacactat ctatttagtt gagggagaat tttatggggt
    12661 tcaactatga agctatcaag gcctacctga ttgaccacgg tgtggatgct agtcttgctg
    12721 agaccatgca cgctatctat gctactagga gaatcggtag gtcaactttt gagtatttcc
    12781 taattgtttt tacagaaaca gaggttttga ttatttctct tactctttta ggaaaattag
    12841 gagatattat cgccaaattt cctgaagaga cgattaagtc ttatcagttt aaaaaacgct
    12901 tgtttattgg ttataaactt cgtatttttc taaatgatgg cagggagcta gactttaatg
    12961 tcaacaagat attgattgga gcggattggc ataagacgga attgcaaagc atcctagaaa
    13021 caaattatta caacaaaaat aattaatata gaaaggacga aagggctcga cctttagagc
    13081 tctacatctt aattatgatt aacattactt tcccagatgg cgctgttcgt gagttcgaat
    13141 ctggcgttac aacttttgac attgcacaat ctatcagcaa ctctttggct aaaaaagctc
    13201 ttgctggtaa atttaacggt aaattgattg acactacacg tgccatcact gaagatggaa
    13261 gcatcgaaat cgtgacacct gatcacgaag atgctcttcc aatcttgcgt cactcagcgg
    13321 ctcacttgtt tgcccaagct gctcgtcgcc tcttcccaga catccacttg ggtgtcggtc
    13381 cagctatcga agatggtttc tactacgata ctgacaatga agctggtcaa atttctaacg
    13441 aagaccttcc tcgtatcgaa gaagaaatga agaaaatcgt taaagaaaac ttcccatcaa
    13501 tccgtgaaga agtgactaaa gacgaagcgc gtgaaatctt caaaattgac ccatataaat
    13561 tggaattgat tgaagaacat tcagaagatg aaggtggttt gactatctac cgtcaaggtg
    13621 aatacgttga cctttgccgt ggcccacacg tgccatcaac tggtcgtatc caagtcttcc
    13681 accttttgaa tgttgcaggt gcttactggc gtggaaatag cgataatgct atgatgcaac
    13741 gtatttatgg tacagcttgg ttcgataaaa aagaccttaa agcttacctt aaacgtcttg
    13801 aagaagctaa agaacgtgac caccgtaaac ttggtaaaga acttgatttg ttcatgattt
    13861 ctcaagaagt tggtcaaggt cttccattct ggttgccaaa cggtgcgaca atccgtcgtg
    13921 tcttggaacg ctacatcgtg gacaaggaag tagcagcagg ctaccaacac gtctacactc
    13981 caccaattgc ctcagttgag ctatacaaaa cttcaggtca ctgggatcac taccgtgaag
    14041 atatgttccc aacaatggat atgggagatg gtgaagcctt tgtccttcgt ccaatgaact
    14101 gtcctcacca catcgaagtt tacaaacacc atgtgcactc ttaccgcgaa ttgcctatcc
    14161 gtatcgctga aatcggtatg atgcaccgtt atgaaaaatc tggtgccctt acaggacttc
    14221 aacgtgtacg tgaaatgtca cttaatgacg gacatacttt cgtaacacct gaacaaatca
    14281 aagatgagtt ccaacgtacg cttcaattga ttatcgacgt ttacgaagat ttcaacttga
    14341 ctgactatcg tttccgtttg tcataccgtg accctaaaga tactcacaaa tactttgaca
    14401 atgacgaaat gtgggaaaat gctcaaagca tgttgaaatc agccatggat gacatggaac
    14461 tcgactactt tgaagcagaa ggtgaagctg ccttctacgg tccaaaactt gatatccaag
    14521 tgaagactgc ccttggtaat gaagaaacac tttctactat ccaattggac ttcttgcttc
    14581 cagaacgctt tgaccttaaa tacatcggag ctgatgggga agaacaccgt ccagttatga
    14641 ttcaccgtgg ggttatctca acaatggaac gctttacagc tatccttatt gaaaactata
    14701 aaggagcctt cccaacttgg ttggcacctc aacaagtaac tgttatccca gtttcaaatg
    14761 aagcccacac agattacgct tgggaagttg ctaaacaact tcgtgaccgt ggtatccgtg
    14821 ttgaagtgga tgaacgtaac gagaaaatgc aatacaagat tcgtgcgtct caaacacaaa
    14881 aaatccctta ccaattgatt gttggtgata aggaaatgga agacggaact gttaacgttc
    14941 gtcgctatgg acaaaaacaa acacacactg aagctgtgtc agaatttgta gaaaatattc
    15001 ttgctgatat tgctcgcaaa tcacgcccag atgccgaata aatcagaaag tcggttagct
    15061 aagctagctg actttttagt aggataaagc atgcacgttt ttaggaaaag acttttattt
    15121 ctgctgggag cagtcctgct cttgttactg tctagcttta cttatcacag attatccttg
    15181 caaagagaga aggcttctct caaccctatg gggcaaatgg tgtctgtcaa tggccatgaa
    15241 atgagcatct ttgtaaaggg ggaggggcca caaactctag tttttctttc tggtgctgga
    15301 acagcctctc ccattctaga ttttaaagac ttgtatgatg ggctttcgaa gcagtataag
    15361 atagtcgttg ttgaaagggc tggctatggt tacagtgagg acacatccaa gtcccgagat
    15421 gtttctgagg ttctttcaga gacacgtcaa gccctagcca agacccatgt atcaggtcct
    15481 tacattatcc tttctcattc gatggcctcc gtagagacac ttctgtggca ggaaaaatat
    15541 ccaggtgaag tgaaagctat cattggttta gattgggccc taccagaaag ttactcccat
    15601 ttgaaaatgc atccccagat tttacgtatg gctcgttggg gaagtcaatt aggcctttta
    15661 aggtatcttc caaagagtct ctatgtgcca aatgagaatc taagtagtag tgatcgcaga
    15721 ctctatcaac ggattgccta tcgtcaaatt ttgtcgaagg ctatgttaaa tgaaagccta
    15781 tctgttaaga aaaatgctaa aaaggttgcc tctagcattg attcgcaaat cccaacctta
    15841 ctaatggtat cgaatggtgg gggtactggt tttagccaga aggactggcg gcattatgcg
    15901 actagctttg caaaggacca gaaaaatatc gaagtgactt tttatgattc tccgcattat
    15961 ctttatcact atccgaccaa agaggtagca gcaaagatag aggagttcat caaaaagacg
    16021 actgattaaa tttacatata ttatcgagga gagatgtgat gctcattggt tcaaaagcct
    16081 ttcgacactt atgggaggac tggcaaaggg actaccagcc attgcaagta ctaaagctat
    16141 tgttagctta tatagggatg ccagaggatt tatcgggaga gcttgaagaa acccaacacc
    16201 ttttatctta ttttgatcct gacttggcac cgcatgattc cttctggaag gatgtcgtta
    16261 aattggtaga cctggctttt cctggtgata gtttgtctaa gaatgcctct attgagagac
    16321 aaatccatca gctacgttac ctgatttcta gtcaacagtc ccagtatgtg cgaacgcatt
    16381 ataaaaagcc agggatgaca gataaagaag ctttggctgt ctatctgaga tggaagcctt
    16441 tcaccatgtt tgatcaggga cgtttgcacc aaaagatttc tatctgtgat ggcaaggcgg
    16501 tttatcctga tgggattcca agtgttaatc taaaaattct tctctataat cggattgagt
    16561 ttattctgga tagtcaggga aactttctca atgaggtcga tgcggagcag gtgaccgaga
    16621 gtggggtggt taatggtgcc agttttaact atggtaattt caaacgccac tggcaactgg
    16681 atgtggagcc ggtccaacca catgaccctg attttcgtaa tcgaatgact aggggctttc
    16741 gttcacccaa caaattgaaa aaacgttggg gacagcaagc gcctgaacag tttgataaat
    16801 ctttctacaa tccaaaaggc atctatgccc agtctcatag gtctttggca aatgatgtca
    16861 aacgccaagc cagatttttt ctcgctctgg tttatggctt taaaccgaat cagaccaagc
    16921 aatcaaagga ggttcatatg tctaaacaac cacaaaacaa taagggaaca gcagttctag
    16981 gctcactagt ctttatggcc ttatacgccc taggtatttg gcacaatgct gtccgaggaa
    17041 atattccctt tctcattctt tggagtgttt tactccttgt taatgtcagc tattttattt
    17101 tccgcttgag aaaataaaaa agaaagtgat acagacctaa atagtaagaa atttaggtct
    17161 gtatcacttt tttgtatatt caatgataac ttaccacttg ctttcttctg ggataataat
    17221 ccagcagatg atgtagaaaa gaaagcctgt tccgaataag aaaatcgctg cagcccaaat
    17281 gaggcgaata atgacagggt cgatgtcaag atatttagcg ataccagaac aaacaccggc
    17341 aatgattttg ttgtttggat ctcgtctgag ttcttttttc atatgattta cctccgtatg
    17401 ccttattata ccataacacc tagaagtcta gtattagctt aaggaagcat gaagtagacg
    17461 atacccagat attggagtgc tgaagccagc atgatgaaga ggtgccaaat catgtggaag
    17521 tatggttttt tcttagcgta aaaagctgct ccaaccgtgt atgacaatcc tccagcaagc
    17581 atgagccccc aaaaggctgg tcctgtctta gtgacgatag ctggaatgat aaagataacc
    17641 aaccatccca tcatcagata gaggaagagg gagaactttt cattgatttt tttagcaaaa
    17701 attttataga gaataccaaa aattgttgtt ccccattgaa ggatgatgat gctatagcct
    17761 agccaaccgc caaccaatga gagggcaaca ggggtgtagc ttccagcaat ggcgatataa
    17821 atcatgctgt ggtcaataat tcttagaacc atcttgtggg gtgaattgta atccatagca
    17881 tggtagatgg ctgagctcaa aaacatgagg aataggctga taacgaaaac agacatcccg
    17941 acagcagctg tcatgccgta gccattgttg gcatgaacag cagtaattgg cagtaagact
    18001 agcatggcca cagctccgac ggcgtgagtc acactgtttg ccacttcctc accaaagcta
    18061 agttttttac tgagtttgag gttgggagaa gtattaaaag tagcagtatt agacattatt
    18121 tcctccttca aggtcgttca aaagttgatg agtagctcgg taacattgaa gcgtctgaca
    18181 ggctgagagt atgacttgtg gagcttcttg gggaaactga ccattcatac aggctacaaa
    18241 gtcattgtag tagctctttt gactttcagc atctgttcgt aggatttcta aggttttggc
    18301 aatctcagaa atctcaaaga cggtcttcag actagtgatg acaataagtc tagctacctg
    18361 agcagcatta tattttttct tgatgggttt tgcgacatgg ccatgtttga cataattatt
    18421 gaccatagag gcggttagcc ccttgtcgtt tggtcccaaa gtgctttggg tgacctgatt
    18481 gacatagagc aaaacctgat ccaaatagag ttcaatctct ggtaattctt cccagagagg
    18541 gtattgttgt gttgtcaaat tataaaaacc tctttatcta gttttcataa ctagattata
    18601 acattataga aattcaagtc aagtcagaac ttgtgagata tgaaaaagat gttgagataa
    18661 aatttccaac atctttattt tttatgtgat aaggcagagt gatattttat tgcttcatat
    18721 tctcttttta tggggttctg agtttctcca aaattgcttg tgcagtttct tggttcatat
    18781 gtttggcctt gagaagttca gccaaaactt gaggcatttc ttcaggactg gccccagcta
    18841 acaaagccag ggatttggct tggagtttca tatgtcctgc ttgtattcct gttgaagtca
    18901 gagctttgag agcagctaga ttttgtgcca aaccaagaga gacgatgata ctggctaggg
    18961 ttttggcatc tggatgatta agcaaatcat gggcgataga agcactaggg ttaagtccga
    19021 tagaaccgcc acgggttgcg attggcatgg ggagggataa ttctccaact agttccttag
    19081 attcctgatt ataagtccat gtggacagac ctcggtagct accatccttg cttgcatagg
    19141 catggctacc ggcctcaact gctcgccaat cgtttccggt cgcgataact agggcatcga
    19201 taccattgaa aattccctta ttatgggtag ctgctcggta ggggtccacc tgagccagtt
    19261 ggctggccat ctccattttc ttagccaggt catgtgcctc ttccttatta cgactgagga
    19321 agcgtgtgct aagacgacaa gtcgctgtca caagactttc agtggctaga tttgagagaa
    19381 tagccatgag gctttgacct tctgacaggt tttctaattc tggcaccagg gcttccatca
    19441 tggtgttgac catattggct cccatggctt cttgggtatc aacggctaga tagacaatga
    19501 ggaagtctcc tttagtctca gtccagagct tgcgagggcc acccccacgc ttaacaatag
    19561 aagggtgagc ctctttggca atctctataa ggtcctgact ggctgcttga attttgcttg
    19621 aagcattatc cttatcagga acgtcaaaga gggcaacttg gccaatcatt tgacggtcat
    19681 ggattgtagt cgtgaaacca ccagaacgct taatgagctt gctagcgtag gaagcagcag
    19741 ccacaactga gggttcctcg gtaaccatgg gaacctgata ggtcacacca tctaccaata
    19801 catctgggca aatggcaaag gggagtgtga atcgaccaat gacattttca gccatctgat
    19861 tggctgtttc aagggtgagt tgttggtcct tatccagaag atcttgattt tcctgagaca
    19921 aaagagcatt cgttttcaaa tgctctttac gttcttgcgg tgtcttcttg gaaaaaccag
    19981 tccaagagag tttagtcata ttaatgtcct ttatagatac gttggtgttc agagatttca
    20041 gctaaacgga aagctccggt ttggtaatca gcgaattgag tagaaccagt gtcatccaac
    20101 tgagcctctt catagaaaag tttttcataa tcagtaacgc ttaagtgttg acgtttggca
    20161 aaggtatcta ggcggtccga acgaagcagg tctttgtatc cttcaaccag acgtcctgag
    20221 aaaatctcag agacagctcc agaaccgtaa gagaagaagc caatcttatc tccggcttta
    20281 aggtcttgcg actgttcaag caaagacaga agtccaagat agagtgaccc tgtatagatg
    20341 tttccaattt gacgactata ggtgattgaa gcgtcaaagt tatttgtcag acgctcttta
    20401 ttctctggat tcaaatcttt tggaataatc ttgttaagtc ccttaagagc tagcttagga
    20461 taagggagat ggagacaaaa agcggcaaaa tcagcaaagt cagcctgatg gcgttcttga
    20521 taagctgccc aagttgtctt caaactgtca aggtactgct tggttgaata gatgccttga
    20581 acataaggcg ttgaactgta gtttggacgc cagaagtcca tgacatcacg agtttgtgcc
    20641 acattatcat cagcaagttc caaaatacgt ggattctgac tgactagcat agctacagca
    20701 ccagctccct gagttgattc accagaagat tccacaccat agcgggcaat atcactagcg
    20761 ataaccagaa ccttgctatc tgggtgggct gccacgtgca atttagcata gttaagtcca
    20821 gcagttgcag cgtaacaagc ttccttcatt tcaaacgaac gggcaaaagg ctgaatacct
    20881 aaaagactgt ggacatagac agcagcagcc ttagactggt caatggaaga ctcagtagct
    20941 acgatgacca tatcgatagc atttttgtcg tcgtcattta aaatatcagc cgccgcatca
    21001 gaggcaagcg tcacgatatc ttctgtaatc ggcgtaatac tggttgcatc aagcatcagc
    21061 cccttgctga atttttcagg ctccgcccca cgggcaagag cgagatcagc catgtttaga
    21121 acatattgac tggtcgcaaa accaatctta tcaattccaa tagacatatg atgtttcctt
    21181 ttttcttcat tgtagagtat ccagaagata ctaatctata gtgattttac cataaaagag
    21241 cgctttcgcc ttgaaaaaac tttgatagtt agttatatct cattttttga taggaactag
    21301 gggattttaa acgacttact tttgctattc catagcttat atttctcatt tacaccagaa
    21361 taaggtaaaa ttgaagtgat aatctacttg ttttttagct atgttagaaa agtaaaattg
    21421 ttgttatata ttgaaatcat tgcgagcgtt aagtgagact ttccgctgtg agataagtgt
    21481 ctgtaaataa agtgttttgt ttatagacac tcggaatttt tgagaccata ggctcaaaaa
    21541 ttagtcttgg aacttcgaag aagttcgcag acgtccgtaa tcacttaagg gaagtctcaa
    21601 aaaatacttt gttttcaata gaataaagag gaaaatcatg acaaaagcag acactatttt
    21661 taaagaaaat atcactaaaa tcatggaaga aggcgtttgg tcagagcaag cacgtcctaa
    21721 atataaggat ggtacgacag ccaattccaa atacatcact ggagcttttg cagaatatga
    21781 cttgagcaag ggagagtttc caattaccac tcttcgtcct attgctatca aatctgctat
    21841 caaagaagtg ttctggattt atcaagacca gacaaacagc ctagatgtcc ttgaagacaa
    21901 gtataacgtg cactattgga atgattggga agttgaaggc gtgcctgcca ataatggaga
    21961 caagcgttca atcggtcagc gttatggggc ggttgttaag aagcatgata tcattaatcg
    22021 tttgctggct cagttggagg ctaatccgtg gaatcgacgt aatgtcatct ccctttggga
    22081 ttacgaggcc ttcgaggaga cagcaggact tcagccttgt gccttccaaa ccatgtttga
    22141 cgttcgtcgt gtgggtgagg acatttattt ggatgccact ttgacgcaac gttctaacga
    22201 tatgctggtg gcccatcaca ttaatgccat gcagtatgtg gctcttcaga tgatgattgc
    22261 caagcacttt ggttggaaag ttggtaaatt cttttatttc atcaacaacc ttcatattta
    22321 tgacaatcaa tttgagcaag ccgaggaact tcttaaacgt caaccctctg attgccaacc
    22381 acgtttggtt ctcaacgttc ctgatggaac taatttcttc gatatcaaac cagaagattt
    22441 tgaattggtt gactatgaac ctgttaagcc tcaactcaaa tttgacttag caatttaata
    22501 aacgttgata atttaagtcc ataaagagct ggcaaagttt tttccaagct ctttttctct
    22561 ttttttgtta gaatggattg taaacttaaa aagaaaagga aatactgtgt ctaaacaact
    22621 cattgctatt tgggcggaag ctcataacca tgttattggg aagaatcaca ccatgccttg
    22681 gcatttgcct gctgaactgg cacatttcaa gaaaacgacc atgggctcag caattctcat
    22741 ggggcgtgtg acctttgatg gcatgaaccg tcgttgtctg ccaggacgtg aaaccttgat
    22801 tttgacacga gacaaggact tcgactgtga gggtgtaacg accgttacga gtgttgagga
    22861 agccctagct tggtttgaac agcaagataa ggatctctat attgctggtg gtgctggtgt
    22921 ctataaggct tttgatgggc attatgatgc actcatcaag acaactattg aggctgattt
    22981 agagggagac acgtattttc cacaactaga tatgacggca tttaaagagg tatcacgtga
    23041 ccgtgtggcc aaggatgata aaaatgccta cgactttagc ataagtcgct atgaaaaaga
    23101 aggagactag gttcatgcaa cgtagtgttt ttgggttatt tactgcatta ttgggagtac
    23161 tttgtgtgct ctctgccatt cctgcctttc gcaagaaacg ttatgggtta gcagtttttc
    23221 tctttttaaa tgcttttacc aaccttgtca atactattca cgccttctat ggcaccctat
    23281 tttagaaaag agtgaggaat aaatggctgg aaatcgtaat gaagaaatgg tttattgttc
    23341 attttgtggc aaaaaccaag aagaagtaaa gaaaattatc gctgggaatg gcgtctttat
    23401 ctgtaacgaa tgtgtggcct tgtcacaaga aatcattcgt gaggaaatgg cagaagaagt
    23461 tttggctgac ttggctgaaa ctccaaagcc aaaagaactt ttggatattt tgaacaacta
    23521 tgtcgtggga caagaccgtg cgaaacgtgc cttggcggta gctgtttaca accactataa
    23581 acgtatcaac ttcacagaaa gtcgtgaaga caatgatgtg gatttgcaaa aatcaaatat
    23641 tctcatgatt ggaccaactg gttcagggaa gactttcttg gctcagacct tggctcgaag
    23701 cttgaatgtt cctttcgcga ttgcggatgc gacatcattg acagaggctg gttatgtggg
    23761 tgaggacgtg gaaaatatcc tcctcaaact gatccaagcg gcagacttca atattgaacg
    23821 tgcggaacgt gggatcatct atgtcgacga gattgataag attgctaaaa aaggtgaaaa
    23881 cgtatcaatc actcgtgacg tttctggtga aggggttcaa caagccctct tgaagattat
    23941 cgaaggaaca gtagctagcg ttccacctca aggtggccgt aaacacccta accaagagat
    24001 gattcaaatt gatacgaaga atattctctt tatcgtgggt ggtgcttttg atggtatcga
    24061 agatatcgtt aagcaacgtc ttggtgagaa aatcattggt tttggtcaaa ataataaggc
    24121 tattgatgat gactcatcat acatgcaaga aattgtggct gaagatatcc aaaaattcgg
    24181 tcttatccct gagtttatcg gacgtttgcc agtccttgct gcccttgaac agttaacggt
    24241 ggacgacttg gttcgtatct tgacagagcc tagaaatgcc ttggttaaac agtatcaaac
    24301 cctcttgtct tatgatggag ttgaacttga gtttgaccaa gatgctcttg aagctattgc
    24361 aactaaggca atcgaacgta agactggtgc acgtgggctt cgctctatca ttgaagaagt
    24421 catgatggat gtcatgtttg aaattcctag ccaggaagat gtgactaagg ttcgtattac
    24481 caaagaagcc gttgacggta cagctgctcc agttttggaa acagcgtaag gaggacctat
    24541 ggctgaagaa caagtcctaa atacgcacaa tgctgagatt ttgctcagtg cagcaaataa
    24601 gagtcactat ccccaagatg accttcctga ggttgcccta gcaggacgct caaatgttgg
    24661 taaatcaagc tttatcaata cccttcttgg tcgtaaaaac ctcgcacgta cttctgggaa
    24721 accaggaaaa acccagttgc tcaatttcta caatattgac gacaagctac gctttgtgga
    24781 tgtgccaggt tacggttatg cccgtgtgtc caaaaaagaa cgtgccaaat gggggaaaat
    24841 gattgaggag tatctcgtga ctcgagacaa tcttcgtgtg gttgttagct tggttgacct
    24901 ccgacatgaa ccaactcaag acgatattca aatgtatgaa tttcttaagt attatgaaat
    24961 tccagtgatc gttgtggcga ctaaggctga caagattcct cgtggaaaat ggaacaagca
    25021 cgaatctatc attaagaaaa aactaaattt tgataaaaat gaccatttca tcatcttttc
    25081 atctgtcaca cgtgacggtt atgatgaagc atgggatact attttggcag aattgtaaga
    25141 aaagctcgga gaaatctgag tttttttctt gtgatagtct ctaactatct ctttgatagt
    25201 ttccacttat tatccaaggg gataatattg tgttaagctt gttttatcac atatattgga
    25261 ggaaactatg gaaaaccata attatgaaaa tgagggtcag ttccaacgga agatgacttc
    25321 tcgccacctc tttatgctct cgttgggggg tgtcattggt actggtctct tcttgagttc
    25381 aggctataca attgcacaag caggccctct tggtgcgata ctatcttatc ttgtgggggc
    25441 tatcgttgtt tacttggtca tgctttcatt gggtgagtta gcagttgcca tgccagtaac
    25501 ggggtccttt cacacctatg ctactaaatt tatcagtccg ggaaccggct ttacggtagc
    25561 ttggctttat tggatttgtt ggacggttgc cttgggaaca gaatttctgg gggcagccat
    25621 gctgatgcaa cgttggtttc catcggtacc agcctggatg ttcgcagcct tctttgcact
    25681 ggtgattttt gggattaatg ctctaagtgt gaggtcattt gcggaagcag aatctttctt
    25741 ctcgtcaata aaagtcattg ctatcctggt ctttatcatc ctgggtctgg gggctatgtt
    25801 tggtttggtc agttttgacg gtcaccgtga ggctattatg ttcaagcact tgacggccaa
    25861 cggtctcttt ccaaatggtg gacttgccat tgtgtcagtc atgttggcag ttaactatgc
    25921 cttttcaggt acagagttaa tcggtattgc tgctggtgag acagacaatc ctaaagaggc
    25981 tgttccacga gctattaaaa caacgattgg acgcttggtt atcttctttg tcttgaccat
    26041 tgtggtcttg gcttcgcttc ttcccatgaa agaagcaggg gtatcttcag cacctttcgt
    26101 tgatgtcttt gataagatgg gaattccatt tgcagcggac atcatgaact ttgtcatcct
    26161 gacagctatc ctttctgctg ggaattctgg actctacgcg tcaagccgta tgctttggtc
    26221 tttggccaat gaggggatgc tcaataaaaa gctagtgaaa atcaataaac atggtgttcc
    26281 aatgacagct cttttgattt ctatggcagg agcagtttta tcgctctttt caagtatcta
    26341 tgcagcagat acagtttacc tagctttggt atcaatcgct ggttttgcag ttgttgttgt
    26401 ctggctctct attcctatgg cacaaatcaa cttccgtaaa cagtggaatt tagaacattc
    26461 tgatgatgag ttggattaca agacgccttt taatccaatc ctaccttata tcacaatcat
    26521 tctgttggcc atttctgttc ttggtattgc ttgggatagt tcacaacggg caggacttta
    26581 ttttggtatt ccttttatga ttttctgcta cctctatcac taccttcgtt ttaagaaatg
    26641 gtaaggaggc cttgcatggc aatatttaaa gactatttag agaataaatc tcccctcatt
    26701 cttcatgggg ctctgggaac agagatggag agcttgggtt atgatatttc tgggaaactc
    26761 tggtcagcca agtacctgct tgacaagcca gaagttattc aaaaaatcca tgaaacctat
    26821 gtagctgctg ggtctgattt gattaccaca tcgtcttatc aggcaacctt accaggcttg
    26881 atagacgctg gactcactaa agaagaagca gagcagatta ttgccttgac agttcagttg
    26941 gcaaagaatg cacgcgataa ggtctgggca actttggatg acagtgagaa ggctaatcgt
    27001 ccttatccat tgatctctgg tgatgtcggt ccttacgcag cctatttggc caatggttct
    27061 gagtacactg gtgattatgg tcagattatc atagaggctc tcaaggagtt tcatcgtcct
    27121 cgaattcaaa ttctcctaga tcatggtgtc gacttgttgg ctttggaaac cattcctaat
    27181 tatctggaag cacaagcttt gattgaactt ctggctgaag aatttccaga agcagaagct
    27241 tatatcagtt ttacagtcca agaaccaggc actatcagtg atgggacttc tctagatgag
    27301 attgcccagc ttgttggcca gtcagaccaa atcttggctc taggaatcaa ctgtagttcg
    27361 cctctgcttt ataatcaggc tcttgctatt cttaaaaatg ctggaaaagc gctcattact
    27421 taccccaact caggtgaggt ttatgatggt agtacgcaga cttggaaacc taaggacaag
    27481 gatgctctga ccttagtcga acacagcaaa gattggcata ctcagtttgg agttaagatt
    27541 ttaggtggtt gctgccgcac acgtccaaat gatattaaag ccttatatgc agagtttaga
    27601 acctagtcaa atttctaatt atttgttata atatgagact gtaaggctat gagctctaca
    27661 cactattagt agaaaatgaa gccagcgtta agctggtttt taaaatgaag aggaaaatat
    27721 gacctacgaa caagaatttc taaaagactt cgaagcctgg gttgttaccc aagttaaagt
    27781 aaacgaaacg gccttggccg ctagcaagaa aatctgggaa gaagatggcg atgagcgtgc
    27841 acgtgatgca agttaccgtt atgaagccaa attggatgct tacaatttcc taattggcaa
    27901 gtttgccaac tatcgtgctg gcaaaggttt ccatgatatg ccggatggct tgttcgggga
    27961 acgtcactat taatagagga tgaaaaagaa aatagcgaca gcactttatg gaaaggtgtc
    28021 gccgattaaa ataggagaat actaaacatg gctaaagtaa aaaataaaaa gaaagctttt
    28081 aaacaccgtt tgaaaaaaca aggacttttc aataatgtta aagcccctgt cccaccagtt
    28141 gcgcctgttc caccagtgcc accagtagca ccacaacctg ttgctgaaac taagacagtt
    28201 gctaaggaag aagtagcagc caaagacctt agtcttgaag cctttgcaga acttccagaa
    28261 gttgaaggcc ttcgttcaaa ccttgtagag actctttaca atgaaggttt gacttcagca
    28321 gaggcttttg ctactgtgac tgaagaagaa gttcttgccc tcaagggtgt cggacctgcg
    28381 acagttaaaa aattgaaaga aaatggtgtc agctttaaag cttaagccta aaaaagatcc
    28441 gaggtgtaga cttcggatct ttattctttg tcttaggaag cattgtttga ttaggaggac
    28501 aagaaaacca ctagcttttt actagtggtt gatagatctg gattatttct ttggattttg
    28561 tttggttaaa ttaagtccaa aaggtaccaa gttttcttga tgcctgcaaa ttcgccccat
    28621 attttcagtg tggcggaaga taataatcaa agccatgatg gtaagaaccc cagtgaaaat
    28681 aaggtcatag ccatctagca agaagtggat ggctggaaac acagccaagg taatcagtcc
    28741 aacaactgca gcagtgacac ttgaaaatga aatcatgctg gttagataga gtgttagggc
    28801 aaagaccaag agtaagaaga cacagtagag tggggcaaaa ccaagaagca ccccagcact
    28861 tgtcgcaacg gccttcccac ctttaaatcc agcaaagatt ggaaaaacat gtccgataat
    28921 ggcaaagaaa ccaataacta aaggtgaaac ctctgtaaca ccaagccaga taggaagaag
    28981 aacagccaag gtacccttga acatatccac caagaaggtg atggtaccag cagtcttacc
    29041 tagaacacga aaggtattgg ttgttccagt atttccagag ccatgctcac gaagattggt
    29101 gtggaagaat agtttcccaa tccagaggcc ggtctgaatg gaacctagca agtaggcgat
    29161 taggattaac aataagattt tcatgagata attatagcat acagcctagt aattgacaaa
    29221 gtcagtcagc cttaagatat cttttgaact ttcttgattt cttttgcaaa ttcttctgaa
    29281 aacttataaa ataataagga tgaaaatttt ggaggtcact cttggctaaa aaagaaatta
    29341 atgtaaataa ttataatgat gatgccattc aggtactaga agggttggat gcggttcgca
    29401 agcgccctgg aatgtacatt ggctcaacag atggaacagg acttcaccac ctcgtttggg
    29461 agattgtcga caatgcggtc gatgaagctc tttctggttt tggtgatgtt atcgctgtta
    29521 ccctaaataa ggatggttcc gtttctgttt ctgactctgg acgtgggatg ccgacaggta
    29581 tgcatgccat gggtaaacca acagttgaag ttattttcac tgttctccac gctggtggta
    29641 aatttggaca gggtggttat aagacttctg gaggtcttca cggtgtgggt tcctcagttg
    29701 ttaatgcgct gtctagttgg cttgaggtag aaattacccg tgacggtagt gtttatcgcc
    29761 aacgttttga aaatggtggt caccctgtaa cagggcttga aaagattggt aaagcgccta
    29821 agtctaagac aggtacaaaa gttaccttta tgcctgatgc gagcatcttt tcaacaactg
    29881 actttaaatt taacaccatc tcagagcgtc tcaaagaatc agccttcctt cttaagaatg
    29941 tcactatgac attgacagac ttgcgtggcg aagaagaagt tcgtgaagaa ttccactatg
    30001 aaaatggagt tcaagacttt gtgtcatatt tgaatgagga caaggaaacg ttgacaccag
    30061 tcatctatat tgatggagat caacaagaat ttcacttgga attagccctt cagtataatg
    30121 acggttactc tgacaatatc ctttcctttg tcaataatgt ccgtactaag gacggaggaa
    30181 ctcacgaaac aggatttaag tctgccatta ccaaggctct taatgattat gcacgtaaga
    30241 cagggcttct caaagaaaaa gataagaacc ttgaagggtc agattaccgt gaaggtttat
    30301 cagcagttat ctcgcttttg gttcctgaag aacaccttca gtttgaagga caaaccaagg
    30361 acaaacttgg atctccttta gctcgtccta ttgttgatag tattgtttca gagcatctga
    30421 cttacttcct tatggaaaat ggggacttag cttctaactt ggtgcgtaag gctatcaagg
    30481 cccgtgacgc ccgtgaagct gctagaaaag cgcgtgatgc tagtcgaaat ggcaagaaaa
    30541 ataaaaaaga caaggggctc ttatcaggga aactgacgcc agcccaatct aaaaatgcta
    30601 agaaaaatga gctttatcta gtcgaagggg attctgccgg tggttccgcc aaacaaggtc
    30661 gtgatcgtaa attccaggct atcctgcctc ttcgaggtaa ggtcctaaac actgagaaag
    30721 ccaaaatggc tgacattctc aaaaatgaag aaatcaatac catgatttac actattggtg
    30781 caggtgttgg agctgatttt aaccttgacg atatcaacta cgacaagatt atcatcatga
    30841 ccgatgccga taccgatgga gctcacatcc agaccttgct acttactttc ttctatcgtt
    30901 atatgcgtcc actggttgaa gcaggacacg tttatatcgc tttgcctcct ctttacaaga
    30961 tgtctaaagg aaaaggtaag aaagaagttg tcgaatatgc ttggacggac ggggaacttg
    31021 aggaacttcg tcaaaaattt ggtcgtggcg ctattctcca acgttacaag gggcttggtg
    31081 agatgaatgc tgaccagctt tgggaaacaa ccatggatcc agagacaaga acccttatcc
    31141 gagtgacgat tgacgaccta gcgcgtgcag aacgccgtgt ctccgtccta atgggcgata
    31201 aggctgcacc acgtcgtcaa tggattgaag acaatgttaa gtttactttg gaagaaaata
    31261 cggtatttta aatactttct actataaaat aaataagcta taatgtagaa atgttaagga
    31321 atcaacatga gaactgatac agaaatgatg aatctgattt tgcaaatagc tgatactctg
    31381 gaagtagaag cgattgcttt atccggatcc cgaacgaatc ctcaggcaac caaagacgag
    31441 tttcaagatt acgatgtagt ctatatagtt gatgatctgg aagaactgat ttcagattta
    31501 tcctggttgg atcagttcgg aaatcgactc atcgaacagc acaaccgact gggacaccgt
    31561 cgtctgtatg tcatgctctt tgaagatggg aatcgtattg atttaaccct ctgcctcaag
    31621 gagtatatcc aagagtgggt ggacagcgaa gcaaattttg aagttataaa agatgacaaa
    31681 ggtttgtttg actcttacat tcctagtccg aagcgctatt ggaccgctcc gcctactgaa
    31741 gaggaatttg cagcatcctg caatgaattt tggtgggtat cggcttatgt tgtcaaggcc
    31801 attcgaagaa atcagcttat ctatgcgacc gaccacctct atggcatttg ccagcaagaa
    31861 cttctcaagg tcttagcttg gcaggtgaca agcgatagag gagcagttga tatcggaaag
    31921 aactacaagt acctcttcca gtatctacca gctgagcaag agaaggagtt ctcagctttg
    31981 cttgatctat ctagtttaga gaagatcagt caatccttat tttcctccat gaagggattc
    32041 gatcgagaag ctcaaattct ggcccaaaag atgggattta cttacgataa ggaagtagct
    32101 gagaaaatga tttcttatgc taaagagaaa ctttctaatc attaatttaa tctattttaa
    32161 actgcagata ggatcctttg gttacttggt gtaactgaat tcctctatat ataaaagact
    32221 actcaacatt ctttgaaagg agttgaacac gccctgagtg ctgtgtgaaa aagacaaatt
    32281 tcttattttc actttgtatt ttacgggctt tgtatcttat gtctaatatt caaaacatgt
    32341 cccttgagga catcatgggg gagcgttttg gacgctactc caaatacatt attcaggagc
    32401 gtgcgcttcc tgacattcgt gacggtttga aacccgttca acgtcgtatt ctttattcca
    32461 tgaataagga tggcaatacc catgacaagg gctatcgtaa atctgccaag tcggtgggta
    32521 acattatggg gaattttcac ccacatggcg atagttccat ttatgacgcc atggtgcgta
    32581 tgtcccagga ctggaagaat cgtgaaatct tagttgaaat gcacggtaac aacggttcta
    32641 tggatggtga tccaccagcg gctatgcgtt atacagaggc acgcttgtca gagattgctg
    32701 gctatcttct tcaagatatt gataaaaaca ccgttccttg ggcttggaac tttgatgata
    32761 cagagaagga accaaccgta ttacctgccg cctttccaaa cctcttggtt aatggtgcta
    32821 cagggatttc tgctggttat gccacagata ttccaccgca taatctgtca gaagtcatcg
    32881 atgctgttgt ctatatgatt gaccatccat ctgctaaact ggataaattg atggaattct
    32941 tgcctggtcc agatttccca acaggggcta tcattcaggg caaggatgag attcgtaagg
    33001 cctacgaaac cggtaagggt cgtgtcgttg tgcgttcacg tactgagatc gaacaactca
    33061 aaggtggtaa ggagcaaatc atcgttactg agattcctta cgatgtcaat aaggcagttc
    33121 ttgttaaaaa aatcgatgat gttcgtgtca ataacaaggt tccaggtatt gcagaagttc
    33181 gtgatgagtc tgaccgtact gggttgcgta ttgctattga acttaagaag gatgctgaca
    33241 gccaaactat tcttaactat cttttgaaat atacggatct tcaggtcaac tacaatttca
    33301 acatggtggc tattgataat ttcaccccac gtcaagtggg cttgcaaaag attttgtcta
    33361 gctacattgc ccaccgtcgt gatattatcg ttgctcgttc aaaattcgac aaggaaaaag
    33421 ctgaaaaacg tcttcatatt gtcgaaggat taatccgagt tatctctatt ttggatgagg
    33481 ttatcgctct tatcagagct tctgaaaata aggctgacgc taaggaaaat cttaaggtca
    33541 gctatgattt ttcagaagaa caagcagaag ctatcgtgac cttgcaactt tatcgtttga
    33601 ccaatacgga tattgtcacc ctccaaaatg aggaagctga tttacgtgaa caaatcgcga
    33661 ccttggctgc tatcattggt gatgagcgta ccatgtttaa tgtcatgaaa cgtgaactcc
    33721 gtgacattaa gaagaaattt ggtaatgacc gtcgttcaga gttgcaagca gaaaccaaga
    33781 ccattgaaat tgatactgca agtttgattg ttgaagaaga aacctatgtc agcatcactc
    33841 gtggtggtta tgtcaaacgt acaagcccac gttctttcaa tgcttcaacg attgacgaag
    33901 tcggaaaacg tgatgatgat gatttgattt tggttcagca agctaagacg acacaacacc
    33961 tcttgatttt cactaatcag gccaatgtga tttatcgtcc aatccatgag ttaccagaca
    34021 ttcgttggaa ggatttggga gagcatttat cacaaactat caccaattta tctaaggatg
    34081 aagaagtgct ttacgcagaa atcctggatg attttgaaac aggtacttac ctagcagcta
    34141 ccaagctggg tcagattaaa cgtttcgaac gcaaggaatt tacgccatgg cgtacctaca
    34201 agtctaagtc ggttaaatac gctaaactca aggatgatag tgattttatt gttacggtta
    34261 cgccaattca attggatgat atcatgatca tcactcaaaa aggttatgcc cttcgcttta
    34321 atgctgacga agtgccagta gttggtgcca aggcagcagg tgttaaggca atcaatctta
    34381 aggatgatga tactgttcag gctgtctttg tggcaaatac tcaaagtttc taccttctaa
    34441 cacaaagagc tagtctcaaa cgtgtagcta cagccgatat tccgcaggct aagcgagctg
    34501 gtcgaggtct ccaagttctt cgtgagctta agacgaaacc gcaccgtgtc ttcactgcgg
    34561 gcccagtctt tacggaaaat gctggtggcg agatagatct tctagcaaca ccagtggaag
    34621 agactcctca gaccttgctt gtaacagcta caacaggtga aacggcagag gttgacttgt
    34681 cccttctaaa tctttcagac cgtactagca acggtagttt cattgaagga ttagcagaca
    34741 aagaagtctt ttctgccaag agtattgaaa gataaagata agaaagcttt gttctcttat
    34801 tagagagcag agtttttttc tttgatggac aaaataagtg ttttaaaaag aattgtcaga
    34861 attttgcaac ataaccttga aattttcaat gaaaaggact atactagaaa gcacatagta
    34921 acagaaaaga ggatatacac atgacagttg atttagactg ggaaaatcta ggatttaatt
    34981 acagtaaact tccattccgt tatatctcat attacaaaga cggtaaatgg gatgaggggc
    35041 aattgactga ggatgcgact ttgcatattt cagaagcatc tccagccctt cactatggtc
    35101 aagaagcttt tgaaggcctc aaggcttacc gtactaaaga tggctctatt caattgttcc
    35161 gtccagatga aaatgctaaa cgtttgcaac gtactgcgga tcgtcttttg atgccacaag
    35221 ttcccgttga caaatttgta gatgcatgta aacaagttgt acgtgcaaat gaagaatatg
    35281 ttccaccata tggtacaggt gcaacacttt atctccgtcc attgttgatt ggggttggtg
    35341 atatcattgg tgtgcatcca gcagatgagt atatctttac catttttgct atgccagtag
    35401 gtaactactt caaaggtggt ttggctccaa caaacttcct tatccaagat gattatgacc
    35461 gtgctgctcc acatggtaca ggtgctgcta aggttggtgg taactacgca gcaagtatgt
    35521 tgccaggtaa gattgcacat gatcgtaact tctctgatgt gatctacctt gatccagcaa
    35581 ctcacactaa gattgaagaa gtgggttctg caaacttctt tggtatcaca gccgataacg
    35641 aattcgttac cccactcagc ccatctatct tgccatctat cactaagttc tcattgcttt
    35701 acttggctga aaatcgcttt ggcatgaaag ctatccaagg tgatgttaag atttctgaat
    35761 tggataaatt tgttgaagca ggtgcctgtg gtacagctgc cgttatctca ccaattggtg
    35821 gggtacaaca tggtgatgac ttccatgtct tctattcaga aacagaagta ggtcctataa
    35881 cacgtaaact ttatgatgag ttgacaggta tccaatttgg tgatgttgaa gcaccagaag
    35941 gatggattgt caaagttgac taattcctaa tagataaacg attattttaa ggcttgctct
    36001 tgcaagcttt tttctttttc ggtagaatta agaagataca ttaagaaagg atggctcgag
    36061 ccaaggatcg ggtataaatc tatgagtaaa aaagataaaa aaattgaaat ccaaattaat
    36121 gatgctaaag tagtcgtcaa taaagcaact attgaaggtt ttgaacttct tgttggtaag
    36181 aaagtcatcg gacaaattgt ggaaattgat ggtaagtttg ccgttgttga caaggaaaat
    36241 gttgtaggtt tccacaaaaa aatggatgat gcagtagctg ccattattga atcatacaat
    36301 cttaatcatt aaaatccaaa gtaaaggctt gctttggtca agaaactgtg atatactatt
    36361 tcttgttctt aaggagagat agcgaagagg ctaaacgcgg cggactgtaa atccgctcct
    36421 tcgggttcgg gggttcgaat ccctctctct ccatgtctaa gaaactgaat cgggatagtc
    36481 gatatcaagt acttagatgt ttttttatag cattttgcta ttggggtata gccaagcggt
    36541 aaggcaaggg actttgactc cctcatgcgt tggttcgaat ccagctaccc cagtaaaagg
    36601 tatcgggtgc attggcaccg tctatgttaa ccattgtctt tgcgggtacc tttaaaaata
    36661 tattgttatc aagggtcaga attggctggc tcttgttgga ggatcttttt agaatgaacg
    36721 aatttgaaga attgctaaac agtgttagcg aagttaacac aggtgacgtt gtaacagctg
    36781 aagttatctc agtagataat gatcaagcaa atgttgttat cgaaggaact ggtatcgaag
    36841 gtgttttgac acgtcgtgaa ttgacaaacg accgtgacgc aaacgttgca gaccttgtta
    36901 aagttggtga aacacttgaa gtgcttgttc ttcgtcaagt tgttggtaaa gatactgata
    36961 ctgtaactta ccttgtatct aaaaaacgct tggaagctcg caaagcttgg gataaacttg
    37021 ttggtcgtga agaagaagtt gttactgtta aaggaacacg cgctgttaaa ggcggacttt
    37081 ctgttgaatt tgaaggtctt cgtggattta ttccagcttc aatgatcgat actcgttttg
    37141 ttcgtaacac tgaacaattt gtaggtcaag aatttgacgc taaaattaaa gaagttgatc
    37201 cagctgaaaa ccgtttcatc ctttcacgtc gtgaagttgt tgaagcagaa gctgcagaag
    37261 ctcgtaaaga agtcttttct aaacttgaag ttggttcaat cgtaactggt aaagttgctc
    37321 gtttgacaag cttcggtgct ttcatcgacc ttggtggtgt tgacggactt gttcacgtga
    37381 ctgaattgtc tcatgaacgt aacgtttcac ctaaatcagt tgtatctgta ggtgatgaag
    37441 ttgaagttaa agttcttgct atcgacgaag aagcaggacg tgtatcactt tcacttaaag
    37501 caacaacacc tggaccatgg gatggcgttg aacaaaaact tgctgctggt gatgttatcg
    37561 aaggtaaagt taaacgtttg actgacttcg gtgctttcgt tgaagtattg ccaggtattg
    37621 atggacttgt tcacatctca caaatttcac acaaacgtgt tgaaaatcca aaagatgttc
    37681 tttcagtagg tcaagacgtt actgttaaag ttcttgaagt aaacgctgat gcagaacgtg
    37741 tatcactttc aatcaaagct cttgaagaac gtccagctaa cgctgaaggc gaaaacaacg
    37801 aaaaacgtca atcacgtcca cgtcgtccaa aacgtcaaga aaaacgtgac ttcgaacttc
    37861 cagaaactca atctggattc tcaatggcgg atcttttcgg agatatcgaa ttgtaagaaa
    37921 aaaagaggca tggaaacatg tctttttttc tattttagag tatgctataa tagtatactg
    37981 ttagcaccct tagtgtaatg gatatcacgt aagattccgg ttcttgagat aggggttcga
    38041 ttcccttagg gtgcaaaaag aaaaacgttg agtgaattgt tctctcaacg ttttttagtt
    38101 ggtaagtttt agtaaaagta tttcataaaa tcttttggca ttgaagggga agaaggcaag
    38161 catacagaaa aaagctatta gcttatccta ataacaaagg aaactacttt attagcacca
    38221 ccatagttga tttattgggg agacagtttg gctaatcttt tgcaatttat taaaaaattt
    38281 gctataatac acagtatctc atattggggt cgttacggat tcgacaggca ttatgaggca
    38341 tattctgcga ctcgtgtggc gacgtaaacg ctcagttaaa tataactgca aaaaatacta
    38401 attcttacgc tgtagcagcc taaacacctg ctcgcgtgac ttctagcaga ttgcttatgt
    38461 ttgtttagag gttttattga tttataagct acgtttgact attgcctagc tggttgaaaa
    38521 gagatttata ggctcgcaga tagaaggctt gagttatgtg tcgtctatct gttaaatgaa
    38581 agacataacc tatggttgta gacgaatatg ttggcaggtg tttggacgtg ggttcgactc
    38641 ccaccggctc cataaaaacc agaggcgtca gccttttatt tgtatatata ggaatttatt
    38701 atgaaaaaac ttttgtcttt gaccgtttta ggtctctcac tttttactct agctgcttgt
    38761 ggaaaatctt cgtccaagac agagacgaag ggatctttgg ataatgaagc ctcaaagatt
    38821 ttaaccgtta agcatgggaa tgttcgccag aactttgata agattaccat ggcaaatgct
    38881 tctcaggaat tttcaggagg ctcaaatctt gatagcttga aggggtggtt tggcgaaccc
    38941 tcatcaacga gtcaggagca ggcaggagat gctaagcttg atgtctataa ctggcagtat
    39001 gacaatgttg ttgttacagc gaagcttttt aacaacagta cagtggttaa gtcaatttca
    39061 aacttttctt acgtccgtga tcctaaaatc acactaaaga tgtatgacaa tcttaaaaat
    39121 ggaacgagct atgatgatgc tgtcaaaacg cttggaactc cagatgttta ctctattgca
    39181 gtatcttcag atgcgacaat gactcaagct ctttggtcat caaacctcgt cgctaagaag
    39241 ggtgaaacag gtagtctgac ccttaacttc aaaaatggtg ccttggaaag caagtcacaa
    39301 gcaaatctga ctaacaagta atcacagtaa aagatgcctt tctaaatcaa tggaggcatt
    39361 tttttgttat aataaaagta gcgattaaaa ttatggagat gtaatgacta aaaaaagact
    39421 attttttata gggatagcag gtttaatact ggtattctta tggcctcttt taaataactt
    39481 catcccctta atcaaggaat ggaccaacgc taagcatgat taagcctttt taagagaagt
    39541 ttttaagcag gctaatttcc aaaatgcact gattcttctt agtctcatga ttctgtcatc
    39601 agctattcct ggagtttcaa gttctatttt ttgtattttt gttggcctac tctatggccc
    39661 tttgcttgcg attccgatga atattattgg taatactttt ggaaatttga ctagttttga
    39721 aattctgaga agacttgaga agccagagaa gtccaaacgc atggagaaac ttctaaacta
    39781 tattgagaac tttaagcatc gttttattgg gatttcactg gccttctcta ttccttttat
    39841 accatcagct ctggtcaatt atgcttgtgt tcaaatgaat ttacccacaa ggacgaggat
    39901 tttggcgaca cttattggag tgacgccagt ctctattgtt tatgcagtta gtggagattt
    39961 gttgcttaat atccgtccga ttcgaatacc attagtggca gtacttgcca tcttgctctt
    40021 tatctcactc gtcatttact ttatccattt taggaaggaa aaaaatgagc ttcattcaag
    40081 taactaaaga agaatttaac acacatgctc aacaagtatc tgagcgttct tttatgcaaa
    40141 ctgaggaaat ggcaaagctt cttgaaaaac gtggatttag cattagctat gtcgcttgga
    40201 aagaaggaaa ccagctagaa gtctcagcaa ttgtctacag catgcctatg actggtgggc
    40261 ttcgtatgga ggtgaattgt ggaccgattc actcaaatac agctcatcta agtgactttt
    40321 accaaggttt gaaggattat gctaaggaaa atggtgctct tgaactatta atcaaacctt
    40381 atgatactta tcaaactttt gatagtaatg gtgaaccaac tagtgatgag cagaagcagc
    40441 tgattagtca attgactgat ttaggttata gctttgatgg tctacagaca ggctatcctg
    40501 gtggtgagcc tgactggcac tatgttaagg aattatctgg gattgaagaa aaagatctta
    40561 tcaagtcttt cagtaaaaaa gggaaacctc tggttaaaaa agccaaaacc tttgggatta
    40621 agttgaaaaa attgaaacgt gatgagttat ctattttcaa agaaatcact tcagcgacct
    40681 ctgaccgtcg tgagtatagt gacaaatctc tagattatta tcaagatttt tatgatgctt
    40741 ttggtgacaa tgctgatttt atggtggcta ccttgaattt tcaggattac tatgaccatt
    40801 tggaaagtga tcaggcgaag ttgggggcta gaattgtcaa attacaagct gatttagaag
    40861 ctaatccaaa atctgagaaa aaacaaaacc aattaagaga gttatcaagt cagtttgaga
    40921 cctttgatgt tcgaaaggga gaagcgactg cctttattga caagtatggt caggaagata
    40981 ttgttctggc tggaagtctc tttgtctata cacctcaaga agctgtttat ctttttagtg
    41041 ggtcttatcc agagtttaat aagttttatg cgccagcact cttacaagag tatgtgatga
    41101 cccaggccat taaacgtggc attacgttct ataacttcct tggtattatg gggatctttg
    41161 atggttc
//
