LOCUS       NZ_CP046591            20270 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain R31 chromosome, complete genome.
ACCESSION   NZ_CP046591
VERSION     NZ_CP046591.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4186822)
  AUTHORS   Yu,G.
  TITLE     Study on the banana fusarium wilt control by endophytic Bacillus
            subtilis strain R31 by regulating banana rhizosphere microbial
            community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4186822)
  AUTHORS   Yu,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2019) Institute of Plant Health, Zhongkai
            University of Agriculture and Engineering, Dongsha, Guangzhou,
            Guangdong 510000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 450.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015602625.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:59:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,377
            CDSs (total)                      :: 4,256
            Genes (coding)                    :: 4,150
            CDSs (with protein)               :: 4,150
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 67 of 106
            Pseudo Genes (incomplete)         :: 47 of 106
            Pseudo Genes (internal stop)      :: 16 of 106
            Pseudo Genes (multiple problems)  :: 19 of 106
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:59:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2787636
            Orig. end                         :: 2807906
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP046591.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20270
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="8"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20270
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20270
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10270](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10270)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            496..1071
                     /gene="yxaF"
                     /locus_tag="GO004_RS14605"
                     /old_locus_tag="GO004_14595"
     CDS             496..1071
                     /codon_start=1
                     /gene="yxaF"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391879.2"
                     /locus_tag="GO004_RS14605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14595"
                     /product="transcriptional regulator YxaF"
                     /protein_id="WP_003227022.1"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
     gene            1163..2176
                     /gene="qdoI"
                     /locus_tag="GO004_RS14610"
                     /old_locus_tag="GO004_14600"
     CDS             1163..2176
                     /EC_number="1.13.11.24"
                     /codon_start=1
                     /gene="qdoI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391878.2"
                     /locus_tag="GO004_RS14610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14600"
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="WP_195727680.1"
                     /transl_table=11
                     /translation="MKTLWKHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGDL
                     FEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTPHS
                     YRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVADIVF
                     LDEEKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQFVVVS
                     SEGPKGDRIVDHYHEHHTETFYCLEGQMTMWADGQEIQLNPGDFLHVPANTVHSYRLDS
                     HYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRVLQNIEALDLKVMKP"
     gene            2284..3492
                     /gene="yxaH"
                     /locus_tag="GO004_RS14615"
                     /old_locus_tag="GO004_14605"
     CDS             2284..3492
                     /codon_start=1
                     /gene="yxaH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391877.2"
                     /locus_tag="GO004_RS14615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14605"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_195727681.1"
                     /transl_table=11
                     /translation="MSSLQPTLANERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSML
                     GKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLY
                     VRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIP
                     FMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNP
                     LNFFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYNVTDK
                     EICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYH
                     YGLGLYGKVYPAAGVLITIAVCAVQMAFSHLWLRVFRMGPFEWLWRSATYLSWQPIVKK
                     TKV"
     gene            complement(3522..3977)
                     /gene="yxaI"
                     /locus_tag="GO004_RS14620"
                     /old_locus_tag="GO004_14610"
     CDS             complement(3522..3977)
                     /codon_start=1
                     /gene="yxaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391876.1"
                     /locus_tag="GO004_RS14620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14610"
                     /product="RDD family protein"
                     /protein_id="WP_015250840.1"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFVINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     misc_feature    complement(4152..4166)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.73"
                     /tool="antismash"
     misc_feature    4153..4166
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    4165..4178
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.05"
                     /tool="antismash"
     gene            4260..4658
                     /gene="yxaJ"
                     /locus_tag="GO004_RS14625"
                     /old_locus_tag="GO004_14615"
     CDS             4260..4658
                     /codon_start=1
                     /gene="yxaJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015715029.1"
                     /locus_tag="GO004_RS14625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14615"
                     /product="DUF5391 family protein"
                     /protein_id="WP_032676939.1"
                     /transl_table=11
                     /translation="MTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGMWSAVGMILV
                     LYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLSEVIFVFGIS
                     LAAAAVNVIWFVAAFRSGAEKTSVNTLT"
     gene            4759..5991
                     /gene="pgpK"
                     /locus_tag="GO004_RS14630"
                     /old_locus_tag="GO004_14620"
     CDS             4759..5991
                     /codon_start=1
                     /gene="pgpK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391873.2"
                     /locus_tag="GO004_RS14630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14620"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_017696075.1"
                     /transl_table=11
                     /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQSTAAYAAETV
                     FSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVI
                     DGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFI
                     DKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNG
                     VVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGN
                     QDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFY
                     TDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLAEDGTLYI
                     GSYTKLMAFGK"
     gene            complement(6055..7254)
                     /gene="yxaM"
                     /locus_tag="GO004_RS14635"
                     /old_locus_tag="GO004_14625"
     CDS             complement(6055..7254)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yxaM"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391872.2"
                     /locus_tag="GO004_RS14635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14625"
                     /product="MFS transporter"
                     /protein_id="WP_003244232.1"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     gene            complement(7251..9494)
                     /gene="asnB"
                     /locus_tag="GO004_RS14640"
                     /old_locus_tag="GO004_14630"
     CDS             complement(7251..9494)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391871.2"
                     /locus_tag="GO004_RS14640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14630"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_033882788.1"
                     /sec_met_domain="GATase_7 (E-value: 3.4e-43, bitscore:
                     144.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 5.6e-94, bitscore:
                     313.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAACNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYHENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSNQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSILRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETHSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLKPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     gene            complement(9515..9997)
                     /locus_tag="GO004_RS14645"
                     /old_locus_tag="GO004_14635"
     CDS             complement(9515..9997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391870.1"
                     /locus_tag="GO004_RS14645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14635"
                     /product="hypothetical protein"
                     /protein_id="WP_003243073.1"
                     /transl_table=11
                     /translation="MEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     gene            complement(10001..10270)
                     /gene="yxbA"
                     /locus_tag="GO004_RS14650"
                     /old_locus_tag="GO004_14640"
     CDS             complement(10001..10270)
                     /codon_start=1
                     /gene="yxbA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391869.1"
                     /locus_tag="GO004_RS14650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14640"
                     /product="PqqD family protein"
                     /protein_id="WP_033882790.1"
                     /sec_met_domain="PqqD_RRE (E-value: 6.5e-08, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-11, bitscore: 41.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.2e-08,
                     bitscore: 31.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIEHEAIKVKQGA"
     aSDomain        complement(10016..10183)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GO004_RS14650_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.70E-10"
                     /identifier="RREFam002.1"
                     /label="GO004_RS14650"
                     /locus_tag="GO004_RS14650"
                     /protein_end="85"
                     /protein_start="29"
                     /score="31.1"
                     /tool="antismash"
                     /translation="TLNEMASDIYNHIDGKVSIHDICSKIVNEYDVDYQTCLEDCMELF
                     ELLIEHEAIKV"
     aSDomain        complement(10019..10189)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GO004_RS14650_PqqD_RRE.1"
                     /evalue="4.30E-10"
                     /identifier="RREFam006.1"
                     /label="GO004_RS14650"
                     /locus_tag="GO004_RS14650"
                     /protein_end="84"
                     /protein_start="27"
                     /score="30.2"
                     /tool="antismash"
                     /translation="GITLNEMASDIYNHIDGKVSIHDICSKIVNEYDVDYQTCLEDCME
                     LFELLIEHEAIK"
     gene            complement(10270..11004)
                     /gene="yxbB"
                     /locus_tag="GO004_RS14655"
                     /old_locus_tag="GO004_14645"
     CDS             complement(10270..11004)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="yxbB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391868.1"
                     /locus_tag="GO004_RS14655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14645"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_033882791.1"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPSGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     ADHEIESVTWMLTIEKEKEGAL"
     misc_feature    complement(11456..11469)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.23"
                     /tool="antismash"
     gene            11513..12505
                     /gene="yxbC"
                     /locus_tag="GO004_RS14660"
                     /old_locus_tag="GO004_14650"
     CDS             11513..12505
                     /EC_number="1.14.11.47"
                     /GO_process="GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /gene="yxbC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391867.1"
                     /locus_tag="GO004_RS14660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14650"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_033882793.1"
                     /transl_table=11
                     /translation="MSAVTESVLESIISPVTMSEFLEEYWPVKPLVARGEVERFTSIPG
                     FEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTD
                     LFIPQVRRWIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWK
                     LAKNKNVSNPMQHYDLSEAPYYPDDLQSYWKGDPPKEDLPDAEIVNLTPGTMLYLPRGL
                     WHSTKSDQATLALNITFGQPAWLDLMLAALRKKLISDNRFRELAVNHQSLHESSKSELN
                     GYLESLIQTLSENAETLTPEQIFQSQDSDFDPYQSTQLVFRQLLTSYKF"
     misc_feature    11558..11571
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.94"
                     /tool="antismash"
     gene            12585..13064
                     /gene="yxbD"
                     /locus_tag="GO004_RS14665"
                     /old_locus_tag="GO004_14655"
     CDS             12585..13064
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="yxbD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391866.2"
                     /locus_tag="GO004_RS14665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14655"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_003244176.1"
                     /transl_table=11
                     /translation="MNIIPTCQIPKDLVSAFFQKHWGSPQMVISSGIYNCDELDGYGML
                     NDDNQIVGLITYIFEEDACEIISLDSVIENKGIGTALLEKAEEACRERNIKQIKLITTN
                     DNIHALAFYQKRGYRLDRLFVNAVETARKMKPEIPLLADNKIPIRDELLLVKELQ"
     gene            complement(13103..14440)
                     /gene="aldX"
                     /locus_tag="GO004_RS14670"
                     /old_locus_tag="GO004_14660"
     CDS             complement(13103..14440)
                     /codon_start=1
                     /gene="aldX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391865.2"
                     /locus_tag="GO004_RS14670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14660"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_195727682.1"
                     /sec_met_domain="Aldedh (E-value: 9.5e-100, bitscore:
                     332.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     TPDRSKFTQIVNDRNFNRVKDLFDDAIKKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDINEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQAAE"
     gene            14583..15725
                     /gene="yxbF"
                     /locus_tag="GO004_RS14675"
                     /old_locus_tag="GO004_14665"
     CDS             14583..15725
                     /codon_start=1
                     /gene="yxbF"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391864.1"
                     /locus_tag="GO004_RS14675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14665"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_033882796.1"
                     /transl_table=11
                     /translation="MPESAEAQVKEALLALLKERDIQHITMKEIAEKAKVSRGSLYLYY
                     EDKFSIIEDLIEDMKEGLGKALFDAFSHMDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFKDVFQQDVLLTPVHVNLTPIEREIYGHYRALYTYAIILYWLNEDAAATPE
                     AISQKVWELVSQKRFYWLFGQAVPGEREKDKQIDRRVVRTREALQKALLDVLAEKKDYA
                     AITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCAEIIDHLTIASSPNEFSLKEAE
                     KALASLLSDLSNMPIVHFLNREWGVPHVIPDMFKALESFYLHQQTDIHAEKKLYAHYVS
                     AMIIGLLLYRLDEGKAHPPEVLAREFLQFLDVKKYKVVLL"
     gene            complement(15755..16576)
                     /gene="yxbG"
                     /locus_tag="GO004_RS14680"
                     /old_locus_tag="GO004_14670"
     CDS             complement(15755..16576)
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 1.1e-08. Score:
                     27.1. Matches aSDomain:
                     nrpspksdomains_GO004_RS14680_PKS_KR.1"
                     /codon_start=1
                     /gene="yxbG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391863.2"
                     /locus_tag="GO004_RS14680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14670"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_033882797.1"
                     /sec_met_domain="adh_short (E-value: 2.2e-30, bitscore:
                     103.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.5e-35, bitscore:
                     119.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEE
                     TVDAIRKNGGQAESFHLNVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     IDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEKFREANKWVTPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWKKETR"
     aSDomain        complement(16097..16555)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GO004_RS14680_PKS_KR.1"
                     /evalue="1.10E-08"
                     /label="GO004_RS14680_PKS_KR.1"
                     /locus_tag="GO004_RS14680"
                     /protein_end="160"
                     /protein_start="7"
                     /score="27.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRK
                     NGGQAESFHLNVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPIDLFDRI
                     IAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       complement(16472..16549)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GO004_RS14680_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="GO004_RS14680"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVII"
     gene            16693..16944
                     /locus_tag="GO004_RS14685"
                     /old_locus_tag="GO004_14675"
     CDS             16693..16944
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391862.1"
                     /locus_tag="GO004_RS14685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14675"
                     /product="hypothetical protein"
                     /protein_id="WP_014481429.1"
                     /transl_table=11
                     /translation="MKVQHKKELKFYCFITIPSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     gene            17112..18992
                     /gene="htpG"
                     /locus_tag="GO004_RS14690"
                     /old_locus_tag="GO004_14680"
     CDS             17112..18992
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="htpG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391861.1"
                     /locus_tag="GO004_RS14690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GO004_14680"
                     /product="molecular chaperone HtpG"
                     /protein_id="WP_085185355.1"
                     /transl_table=11
                     /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFIPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKFIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     misc_feature    complement(20115..20128)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     misc_feature    complement(20149..20163)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.05"
                     /tool="antismash"
     misc_feature    20150..20164
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.15"
                     /tool="antismash"
ORIGIN
        1 ccgaaagtcg agacggccgc attgttgacc catgtgtcaa agcggccgaa tgtgctgatc
       61 gcggtttctg cgatgcggtt gacgtcctct tcttttccga catccgcctt tacccatatg
      121 gcgtcgtgcc ctttttcctt aagttcatca gtgagctcct tcagcgcgtc ttcatttcgc
      181 gctgctgcca cgaccttggc gcctttttca gctgccatac gtgccgtgac aagtccgata
      241 ccgcttgaag cgccggtaat gacgattacc tgatccttga gttttttcag tttgagcttt
      301 gtttttatgg cggggttctg ttgttcaagc tgctctgtat ttgtgactga atgatcgatt
      361 gtcattgaga gatccctcct agacgctgtt tttgtacatt accccatccg gaagggtctt
      421 accccttttg acaatcacag ggttcttttt tatattatat aagtcgctct accataccta
      481 ggagggaatg ttttaatgac tagcagagga gattcacggg aaaaaatcct tcacacggcg
      541 tcacgtctgt tccagctgca aggatatcac gcgacaggtt tgaaccagat tgtaaaagaa
      601 agcggtgctc ctaagggatc gctttatcac ttttttccga atggcaaaga agaattagca
      661 attgaagcgg ttacatatac aggtaagatc gttgaacatc tgatacagca aagcatggat
      721 gaatcctctg atcctgttga agcgattcag ctttttatca aaaaaacagc cagccaattt
      781 gataacacag aaagcattaa aggtattcca gtcggtttgc tggcgagtga gacagcgtta
      841 atcagtgaac cgctgcggac ggtttgcatg aaggtgttta aaagctggga agcggttttt
      901 gccagaaaat taatggaaaa cggatttgca gaagaagaag caaatcagct tggaacgctg
      961 attaattcga tgattgaggg cggcatcatg ctttcgttaa cgaataaaga caaaacgcct
     1021 cttcttctca ttgccgaaca aataccagtg ctggtgagaa aaaaagggta gcattttgtt
     1081 atcctttctc ctacaattat atagaacggt ctagtaagaa agttatagta tatagactgg
     1141 tctaaattgg aggaaatgat ttatgaaaac attatggaaa cattcattgc ctaaagaaaa
     1201 aatgccttat ttgctccgga gcggagaagg cgagcgctat ctgttcggca gacaggttgc
     1261 cacggtgatg gcgaatggga ggagcacagg tgatttgttt gagatcgtgc ttctttccgg
     1321 gggaaaagga gatgcctttc cgcttcacgt ccacaaggac acacatgaag gaattctcgt
     1381 tttggacggg aaactggaac tgacacttga tggtgaacgc tatttattaa tatcaggtga
     1441 ttatgcgaac attccggcgg gaacaccgca cagctaccgg atgcagagcc acagaacaag
     1501 actggtgtct tacacgatga aaggaaacgt agcgcacttg tattccgtta ttgggaatcc
     1561 gtatgatcac gctgaacatc cgccgtacgc aagcgaagaa gtctcaaacg agcgatttgc
     1621 agaagcagcc gctgtagcgg acattgtatt tctagatgaa gaaaagcctg catgttcggc
     1681 caaattagcg gaacttacag agctgccaga tggagcggtt ccatacgttc ttgaatctgg
     1741 agaaggagat cgcctgttga ctggagatca gcttcaccgc attgtggctg cacaaaaaaa
     1801 tacagatggc cagtttgtcg tcgtatcatc tgaaggccct aaaggtgacc gaatcgttga
     1861 tcactaccat gaacatcata cagaaacatt ttattgcctt gaaggccaga tgacgatgtg
     1921 ggcagatggc caggaaattc agctgaatcc gggagatttc ctgcatgtcc ctgcaaatac
     1981 cgttcactcc tatcgccttg attctcacta tactaagatg gtgggcgtat tggttcctgg
     2041 tttatttgaa ccgtttttcc ggacgttggg cgacccgtat gaaggccaca tcttcccatg
     2101 tgagcctcag gctttgcgtt ttgatcgcgt tttgcagaat atcgaagcat tagatttaaa
     2161 ggtgatgaaa ccataaagat gacaagattg taaggttttc atgccggcct gacacctaaa
     2221 tcgatgtttc cgcgcttcct tttttcatac ccttaaggta cagaaaaaag gagcgtgatg
     2281 gctatgtctt cattacagcc gactttggca aatgagcgga tcggtgtgct tgatgtgctg
     2341 agaggaatgg cgattttcgg catcttattt gtcaatctgg cacatttcag ttatccggat
     2401 atgtatttgt ctatgcttgg aaaagagaat tttttcatgg ataagtggtc tgaagctgat
     2461 tttgccgccg cagacatact gaaattcttc attcaaacaa aatgtatttt attgttttcc
     2521 tttttatttg gatttggcat ggttgtcatg atggagagag cagaaaacaa agggaaacgg
     2581 tttgttccgt tatatgtgag aaggttaatg gcgcttctct tgtttggaac gattcatgcc
     2641 tttttgatat gggacgggga tattttaaca gaatatgccc tgctcggatt tgtcctgctc
     2701 ttgtttcgaa aagcaaagcc gaaaacactg ctgatatggg cggtctcttt gtatcttctg
     2761 ttttccattc cgttcatgtt gacaagtttt gatcaatcaa acggacagga atgggtacaa
     2821 gcggtaacac agcaggcaaa acaagcgatt catgtttatg gaagcggcag cctgaaggat
     2881 attgcagaac agcggatcca cgaccgtctt gtttacatgt cttcgaatgg catgcttacg
     2941 tataatccgc tcaacttctt ctttgcatcc attccatatt tcagcatgtt tttgctggga
     3001 gctgcggcag cgaaatctcg gtatttgcat gaaccagaaa agcatcgcaa aggattaaaa
     3061 cgattatgga tggctgggct tgtcatcggc atcggcgccc aggtgctgta caatgtaacg
     3121 gataaagaaa tatgtttgct gattggcgcg cctttcctca tgtttttcta tgttacaacg
     3181 gttgtctatc tttatcataa aacaagagtg agaacagtgc tgcaatcatt ctccgctgtt
     3241 gggaggatgg catttaccaa ttatttgatg cagtctattg tgtgtacttg gattttttat
     3301 cattacggct tgggcctgta tggaaaagtg taccctgctg cgggtgtgct cattacaatt
     3361 gctgtttgtg ccgttcaaat ggccttcagc cacctttggc ttcgtgtctt tcggatgggg
     3421 ccgtttgagt ggctgtggag aagcgctacg tatctgtcgt ggcagcctat tgtaaagaaa
     3481 acaaaagtct agatgcctat tggcgtctag acttttttct attatttata cacgacacgt
     3541 gttttgcaaa tgatgtcatg caggcctttt ttctctccaa aggcgatcat gataaacccg
     3601 atataaaaga tgattccaga taagatatag gcaaagtaac ggccaattcc ctgtccgaca
     3661 gaaacccgtt caccttgttc attgaccact ttcaggccaa gaattttttt gccaagtgtg
     3721 ccttgcattt tagaagctgt gagcagcccg taatataaca cactgatgac gatcatgatc
     3781 agcatagtag gcaaaaatgc aagcgtcatg tatttcacta aatactcttc ttccgtcatg
     3841 taagggtttg ttgccacagc cccagctaca aaaacagaat tgatcacaaa tagaataata
     3901 taactaggaa cagatacaat aatgccatca ataaaataag ctaaaaaacg aatccaaaat
     3961 cctgctggtt tttccatgta tttttctctc tcctctgaat taatctggaa tagtatactt
     4021 tgaaaaacaa gtacatgcaa tatggtatgg tgataaaatc ctgacattac agaaaaatga
     4081 gtcttttatc ctttgttttt tactatataa atatactaga aagaagcata gcatttgtgt
     4141 atgtgttctg gaatttttta aaaatataat gaatataaca ttcaacttac ttataataaa
     4201 aaaggttaat atttctatta aaggaggagt ttgatgtcaa aaaaaatagc gtggcgatca
     4261 tgacaaccat ttctgcgttt cttttttgcg ccgtgattgt ggcggcttca ctttcgccgc
     4321 tggccggaac gggagcggcg gccaatcagt ttaattcagc tggcatgtgg tcagctgtcg
     4381 gtatgatcct tgtcttgtat ttcattccat ttctcgttta tatgctcgga gtcgatgcaa
     4441 tgaggtatgt catggcggtg ctttgcggct tcgggctttt gattcatttg tcttcggccg
     4501 gttttatctt gatgtttagt ttctttagtg accatctgct ttctgaggtg atctttgttt
     4561 tcggaattag tctcgctgcg gctgctgtca acgtcatttg gtttgtggct gcatttcgat
     4621 cgggtgctga aaaaacgtcc gtgaatactc ttacatagtt ttctagtttg tgatgttttt
     4681 gtgaaataga tttataaaat ggatgaatat gttatgatgg tcgcaaatta gaagttacat
     4741 ataatggggg tctcaatgat ggtcaagtca tttcgtatga aagctttgat tgcgggagct
     4801 gcggtggcgg cggctgtttc ggccggcgct gtttctgatg tgcccgctgc caaagtgctt
     4861 cagtcgacag ctgcttatgc ggcggaaacg gtgttttctc aaaataatgg agcatctggc
     4921 tttttgccag gaagatatga tgtacaagcg atggcacctg ccatgtttaa ctggtcacgc
     4981 gaaagccggt tcgccggaaa tacagacggg acgctgaaat ggcaaaacga catcagaacg
     5041 actccgcaaa atggagcggg ggctgtgatt gacggagacg gcacagtata tcttcattcc
     5101 agagacgggg aaatgaaagc ctttaatcca gacggctcag tcaaatgggt gactggcaat
     5161 cttggaaaaa catatacgca atctcctgta cttgggacca acggcgttat ctatttggca
     5221 tcctatgaca aaaagattta ttttattgac aaagaaacgg gagaaatttt aacaacggtt
     5281 ccgttaagcg gcgggccaag ctctgaaacg gtgatcggtt cagacgggac gttgtatttc
     5341 tcaacacttg ataattatgt tcacgcgatc aaaccgacgt caaaatcaac ctggacagag
     5401 cgctggaagt tgaaaacaaa tggtgtcgtc agctctgtgc cggtgcttgc caaaaacggc
     5461 accgtgtatg tcggcacata taattacgtg ttttatgcga tcaactccgg aaccggacag
     5521 gtgaaatggt ccagaacgac gtcaaatgcg tttaaaggat atccggtgat tgataaggac
     5581 ggaaacattt atgccggcaa ccaagatgga cagctgtatg cctatacatc aacaggcagt
     5641 ttgaaatgga cattcccgtt aaacgggttc tccagctcat ctcctgcgat tgatcataat
     5701 ggcaatatct acatcggctc aggaagcggc gagctgtttt ccatcagcaa aaacggggat
     5761 atgaactggt cattctatac agacggtcct gtcagaacgg cgccgctgat tgacgcgaag
     5821 ggaacggtgt atttcgggtc agatgatatg aaggtttatg cggcagacgc aaacggcaat
     5881 gaattatgga gctatcaaac cgacagcaac gtcgtgtcat ctcctcagct cgctgaggac
     5941 ggaacgcttt atattggaag ttatacgaag ctgatggctt ttgggaaata actgaataga
     6001 atagcagaag accttctttt aataagaagg tcttcttact gtgatacaaa acatttacac
     6061 ttgctgggat ttttcaatct gaactttcat atcattgtct ttaatcttag gcactatcgt
     6121 ataaaggata atagggatta atagaaatac agctacaaca acaaacatgg cagagagccc
     6181 aaaggctgcg gaaatgatgc cgaaaatgac accggaaaga atttctccaa ttgctcctac
     6241 ccctgagttt aacgagaaaa gtgtgttctt gtatgaatcg gggaaaaact tatttaagta
     6301 acttgttacg atcggatgat gaatatcttc aattgcaagc aaaaacgctg tacatggaat
     6361 gcccagcggc ctgaatgctc tagacaatag aaaagtcatg accatgccca tggaatccaa
     6421 tgaggttaaa gcgagatatg gatttttttc gatcttcttt tcgaacctga tggttaatgt
     6481 caaaagaacg agagcggtaa accctcctag ggcaaaaata tatcccagtg acttttctga
     6541 aaagcctaaa tcactcaaaa aaggctgcca gtaacgggaa attgtgtcat aggctgtggc
     6601 tgtaaagaaa ccggctatga cgattaaaag aacccttttt ttgttaaaga taatttttaa
     6661 actttctttg ataatcttta tcgaatcatg ttggttctga tccccatgat ttgtttcgga
     6721 aacagaaggg actttaataa atacagacat ccaaataaat agtaataagt agatcaccat
     6781 aacgagcagg aaaggaaaat agatatttaa tgaatacaaa tacccgctgg caatacttcc
     6841 aataattaaa aaagtgatta gcaattgtgt gtttttcatc atttctttgc cgaatcgatc
     6901 ttcccctgcg acacggctca tccaagtttc aaaagaaccg gaaattaagg aatctgataa
     6961 agcccatatg atcatagcca gtatgcaaat agcagctgaa tcgataaaag ggaagaaggc
     7021 ccatgtaagg atggagaaaa agaatgaact ggcaattgaa attttaattc cataacgatc
     7081 agcaaaaacg ccggaaggaa cttcaaatat aagcttagca atttcaagta ccgctcccat
     7141 taatccaatc tgaaggaaat cataatcttt agatatcaaa taaagaatcc aaataggcga
     7201 aaaaatcccc attgctaatc ccctaagtgc ggaaaacgaa taaaagatgc tcatctatat
     7261 gctccttctg gcagattttt ttgtttgatc aaaatgatat tgtgttcgat ggcttcttga
     7321 atatatttgg ccacttcttc aaggctgaca ccatgtctgt ctaaaatcgt atgaagtgtg
     7381 tcttttccat taatatcgca gagaatatgc agccaagctc cgacgtcttc ctccgaaaca
     7441 ataaactgaa taaatccttc ttccgcaatg tagatgcaat gctcactatc gctttccggc
     7501 tttaacagag tgacgccagg gtttagcgcc aaaatatctt gtccttcaca cttattggct
     7561 gagatattta aacggctggc aatatcacct tcctgtgagt gccagtcttt tattgttatc
     7621 gattctaaat ggctggttat gtctaattga acagaatggg tttctttagt catttttgat
     7681 aaaagtccca tgttcaccag tcttaataaa aattcaaaat ttgtaaactc aggatcatcc
     7741 tccaaatatg tcatgatggc atgaatgtgt tcaacctgta ttatgctgga ggcatcgctg
     7801 tgagagaagg cctcctctat aagctgataa ttgtttttct tcagaagatg aaacatcatt
     7861 ttatgtgtat atctcacgtc cttaccatag aaaaaaggaa cctttggccg gtgggtatag
     7921 cttgtatgca gctcatttgt taatgatttt cgcaatatcg acttatccca taacaagtct
     7981 ttacggagtc catcaggtat tccgcaaacc cattcaacaa gccgatggtc caagaacggt
     8041 acacggtttt cgatatgatt agccgcggcg atccgatctt catgccagca attatacatt
     8101 tgcaggtcac ggtattttgt caggacatac gattgccaag gatctgcttg gttggaatca
     8161 ttgctcttta aataagaaag gtttatagga gaaagtccaa aatgctcctc ccacactcta
     8221 aagatatttc cctgcagccg atgcagccgg ttcatctcca tcgtattgac cgattcaata
     8281 aatccttccc aacttgggtt ctcggctggt gaaagtgtcg tgctgtaacc gccgttaaat
     8341 tcgtcgctgc cctggccggt cagcatgact ttcaggtttg gccttatcgc tttggcatac
     8401 ttatgtaaat gaaacttata taattgttcc ggtccgcaaa acggtgtttc acagatccat
     8461 aacaaatgtt tatatgactc tggttgtaat aactcatcgt tccctaattg atagagaacc
     8521 tgatgatttg gaaggtgtaa atctttagcc agccaatggg catattttgc atcttcattt
     8581 gtaaatgtac tttggcttaa tactgtaaac gtatggagat cctgtttttc tgcagcaaaa
     8641 tgtgcgactg cagctgaatc aatgccaccg ctaagaaaca acccgacttc aacgtcgctt
     8701 tgtaaacatc tatggactga atctgccagc agttctctat atccttcaat caggtcatcg
     8761 ggatggagat tctcatgata gccttgcctg agcaaaatat cctgtaaaga ccaatagctt
     8821 gctgtttttc gttcatttgt tgtcaaatta atttcgagat aatggccagc atcgagattt
     8881 tggatgttta caaaaaagga agtggtttct ttatgattac aggctgcttc cccgcttagc
     8941 caaatgtctg agagtgcttc tttccaatta aattggcggg gacagtgagg atgagaaaat
     9001 agggatttta tttcagaggc aaatataagc tcgtgtttta gctctgtgta aaaaagcggt
     9061 ttaatcccaa agcggtcacg aactaaaaat actttgtttt tatttttgtc ccaaatggct
     9121 attgaaaaca ttccgatgat gtcgtctaca aatccaatcc ctttttcttc atataaatga
     9181 acaattactt cacaatcaga tgtcgtttta aacatatgat tgtgtaaaga agccttcagt
     9241 tctttatagt tataaatttc tccatttacc ataacgacga ttgatccatc ctcatttaaa
     9301 aagggctgct gtccatttac aaggtcaaga atggacaatc gccgaaatgc aaagccgact
     9361 ttggaatcaa tatgatattg ttcatcatcc ggtcccctat agctgatggc atctgccatg
     9421 cctttcaata tatgaaaggt acattcctga gaacggggag cagccagatt tataataccc
     9481 gcgagcccgc acatatgtct ccctcccaat agcgttattg atgtttatag atataagctg
     9541 tctctacatc tgtttctttt acaatatcga ttttaattcc gagacgtttt gcgttttcga
     9601 ttgcgagaat ggaagcgtac gcagaaaatt cttcgggatc aatttcaaaa taaaaaaagg
     9661 cctcactagg ttctttttca taccaagtgt gggtatttac gacatattta tcttctgttt
     9721 caaacaattc aattttgtca taaagtaaac gtcttccttt tataaagagt tccacaaatg
     9781 atccaactgg ttgttggctg ttaatgtgtc tccactcatc ataatatcct ctttcctcat
     9841 attgctcgtg aatccagctt acaatatctt gatgagtcaa tccttgtttt ttggcaaagg
     9901 caagcagagt gatgatgtaa tttacgattg atttagaacg gtgtgtactc agctcatgta
     9961 catcgtctgg taaagcaagc actttttgtt tttccaattc tcatgccccc tgcttaactt
    10021 tgattgcttc atgttcaata agcaactcaa acagctccat acaatcttct aagcaggttt
    10081 gataatcaac atcatattca ttgacgattt ttgagcaaat atcatgtatg ctgaccttgc
    10141 cgtcgatatg gttataaata tctgatgcca tttcatttaa agtgatgccc ggctctataa
    10201 taatgctttt caaatatttt cttgatggca tttctggatt tttggataaa acagttgatt
    10261 cattgatcat tacaatgcac cttccttttc tttttctatc gttaacatcc atgtgacaga
    10321 ctcaatttca tgatcagcac tttgatcatt ttgttcccac aggggagcat cctccagctc
    10381 atctaagctt tctataaaat cctccggtaa aaagtgaaag gtttctaatg aataattggg
    10441 aatgccggca tcctgaacaa actggtgaat gtcttcaaag gaataacttt cttcaaatgc
    10501 ctctcttaca aacctgaagt attccggttc tttgatttgt tttcgcataa tctctaaatg
    10561 gcttccttgg ggattaaatg tatccaaaat gacaattttt ccgctcggag ccagaactct
    10621 atagcactct ttaagtcctt taacaacgtc ttcccaatga tgcaggcaag agtaggagac
    10681 gatgaagtca gcatattggt cagcgtaaga taaatggtgg acatcttcca aatcaaatga
    10741 aatcaggctg cttactccgc tttttttagc ttcttcttga gcgatttcat gcatggccgg
    10801 gttaatatcg acagcatgca cgtgcgcatt tgttctttta gccaactgaa tgcttaaata
    10861 acctggacct gtgcccatat cgataatgac tttgtttttg ggggaataca tccgggacag
    10921 tctggcgcca agcaaggggt aaagatagga ttggtaaaga tcaacaaatt ctttgtacgt
    10981 tctgcattct tcagccgtaa tcatcttcag catcctcctt atcaagttgg cgtgatagcc
    11041 tcaaacgtta atcgttttgg ataagattaa tgaccgccag ctgctacagc gcggcgcaat
    11101 tcaaaaaggc gaggtttctt ataagctttt ttcattgagc atccctccta aaatagagta
    11161 ctagatgtca aatgctatat gagattaatg gccgccagct gctacagcac ggcgcagttc
    11221 aaaaaggcga ggtttcttat aagctttttt cattgagcat ccctcctaaa atagagtact
    11281 agatgtcaaa tgctatatga gattaatggc cgccagctgc tacagcacgg cgcagttcaa
    11341 aaagacgagg tttcttataa gcctttttca tccttttccc tccttccttg taaaaaaata
    11401 ggctatcacg cacaactaaa tattataatc ctctgataat tctgtcaata tttactttta
    11461 gaaaaaaatg ttatatcttt gtggtgaagt tacttttttt gggagggata atatgagtgc
    11521 tgtaaccgaa tcggttttgg agtctatcat cagtcctgta acgatgagtg agtttttaga
    11581 agaatattgg cctgtaaaac ctttggtagc cagaggagaa gtggagagat ttacaagcat
    11641 accggggttt gaaaaggtta gaacgctaga aaacgtattg gctatctaca ataatccagt
    11701 catggtcgtt ggtgatgctg tgattgaaga atctgaaggg atcacagaca gatttcttgt
    11761 gtcacctgca gaggctttag agtggtatga aaaaggggct gcattagagt ttgatttcac
    11821 cgacctattt attccccaag tcagaaggtg gatagaaaaa ctcaaagcgg aattaagact
    11881 gcctgcgggt acttcttcca aagccattgt ttacgcggcg aaaaatggcg ggggattcaa
    11941 agcccatttt gacgcctaca ccaacttgat ttttcaaatt caaggtgaga aaacatggaa
    12001 gcttgccaag aataaaaatg tgagcaatcc aatgcagcac tatgatttat cagaggctcc
    12061 ttactatcct gatgatttac agtcatattg gaaaggagat ccgccaaaag aggatctgcc
    12121 agatgcagaa atcgttaatt taacaccggg aaccatgctg tatttgccaa gaggtttatg
    12181 gcactccacc aaatctgatc aagcaacgtt agctttaaat attacatttg gccagcctgc
    12241 atggcttgac ttgatgctag cagctcttcg aaaaaaatta atcagtgata acagatttag
    12301 agaactcgct gtaaatcatc aatccctaca tgaatcgtcc aaatcagagt taaatggata
    12361 tttggaaagt ctgattcaaa cgttatcaga gaacgcagag acattgaccc cagagcaaat
    12421 cttccaatct caggattcag attttgatcc ttatcaatcc acgcaattgg tattcagaca
    12481 gcttttgaca agttataagt tctagtaaat actagataag gggattaatg acataaaata
    12541 ggttgttaat tctcttattt ttgttcagct aaaaggagga aaatatgaat attattccga
    12601 catgccagat acctaaagat cttgtttccg cgttttttca aaaacactgg ggcagtccgc
    12661 aaatggttat ttctagcggt atttataact gcgatgaatt agatggttat ggaatgctca
    12721 acgatgataa ccagattgtt ggccttatta catacatatt tgaagaagat gcctgtgaaa
    12781 tcatttcgct ggatagtgtc attgagaata aagggatcgg aacagctctg ctagagaaag
    12841 ccgaggaagc atgcagagag agaaatatca aacaaataaa actgatcaca accaatgata
    12901 atattcatgc attagcgttt tatcagaaga gagggtaccg gttggatcga ctatttgtga
    12961 atgcagtcga gacggccaga aagatgaagc ccgaaattcc tttactggca gataataaaa
    13021 tacctatccg tgatgaattg cttttggtca aggagttaca ataaaaggcg ctcctctaag
    13081 gaagcgcctt ttgatcatgc gattattcag cggcctgaat aaatacaccc ttctcatgag
    13141 aaaactcttt gaatccgtat accccatgat aggagccgat tccgcttgtg ttgacgccgc
    13201 cgaatggcag gttgacgtca ctgaaatgga cgacgacatc attgatggcg gcatttcctg
    13261 atgtcgtgtg ctgaaggacg ttgtcaatca ggtcttggtt tttgctgaac acataaagtg
    13321 caagcggttt atcgcggtca tttacgtaat cgatgacctc gttgatgtct tcatagttca
    13381 tcattggcag aatcggtgcg aagatttcct cctgcatgat tttcatgtca ggcgtgacgt
    13441 ttttcaaaac ggttggcgag atcgtgcggt cgctggcatc aaatacgccg ccgaacacca
    13501 cttccgcccc ttttttgatg gcatcgtcga acagatcttt gacacggttg aagttgcggt
    13561 cattgacgat ctgcgtaaat ttgctgcggt ctggggtatg atcatcctcc ataaatccag
    13621 cgttgacgac tgtttgtaaa atccccgcga acctgtcctg aacgtctttt ttaatgaaca
    13681 ggtaatcagg tgcgatgcag gtttggccgg cgtttacgaa tttcccgacg gcgatctttt
    13741 tcgctgcgtc catcagatcg tattcactgt caataatcgt cgggctctta ccgccaagct
    13801 caagtgtgac agatgccaag tgtttggcag ccgctgtcat gacgattttc ccgacatttg
    13861 tgcttccagt gaagaaaata tggtcgaacg gctgatcaag tagttcggtt gccacctcaa
    13921 cctctccttc aaaaatcgcg acttcttttt catcaaaagc gtctcttatc actttagcgg
    13981 caatgttgct cgtgttcatc gtgaaatcgg acagcttcac aatcgcgctg tttccggctg
    14041 cgagagaagc ggcaagcggc gccatcgtca gcataaacgg atagttccac gggccgagga
    14101 tgagtgtgac gcctttaggc tcgtacataa gaattccgtt tgcgtcaggg cttaacgatg
    14161 aaccgacttc tttaggcgcc atccattgtt ccaggttatt catattatct ctgatcgctt
    14221 tttttgttcc ttcgatttcc gcttttttga cttcgtgata tggtttgcgg acgtctttgc
    14281 ggatcgcttc gatgatttct tcttcatggg cgatgacgga atctaaaaag cgttgaagct
    14341 tttctctccg ctgttccgct gttgaagcgc gcaaggcttt ttgctgtttt ttctgaagct
    14401 gaaaaacgcg ctgaatgtcg tcctttactt gctgttccat tgtaaaatcc ccctcatttg
    14461 ctttcttctt ttctcggacc tattataagg tggtaccttt tctgtaagaa agacaacggt
    14521 gaaccatcta tacgttaccg tacatatatc gaacatttgt ctaatgattg ggggtgtctt
    14581 ttgtgccgga atctgccgaa gctcaagtga aagaggcgtt gctggcctta ttgaaagaaa
    14641 gagatattca acacatcaca atgaaagaaa tcgctgagaa ggccaaagtg agccgcggat
    14701 cgctctacct ttattatgag gataagtttt caatcattga ggatttaatc gaagacatga
    14761 aggaagggct gggcaaagcg ctttttgacg ccttcagtca tatggatacc ctccatttga
    14821 acaaaaaacg gcaaacggtg catccgacgc tatcctttgt tcatgagcat cgatcctttt
    14881 tttctgtgat gatgaacaga gggcatttcc atcgtttttt taaggatgtg tttcagcagg
    14941 atgttctgct gactccggtc catgtgaatt tgacgccgat cgaacgggaa atttacggac
    15001 attaccgggc cttgtacacg tacgcgatca tcctgtattg gctgaatgag gatgcggccg
    15061 cgactccgga agctatcagc caaaaggtat gggagcttgt ttctcaaaag agattttatt
    15121 ggctgtttgg acaagctgtg ccaggagagc gagagaagga caagcaaatc gacaggcggg
    15181 tggttcgaac gagagaggcg ctccagaagg ctttgctgga cgtgctggcg gagaaaaaag
    15241 actacgcagc catcacaatt tcggatatta cccggaaaag caatatccgc cgtgcaacct
    15301 tttatgatca ctatgccaat aaggaggaat tgctccaaac catgatacag cgatcatgtg
    15361 cggagatcat tgatcacctg acgattgcct ccagcccgaa tgaattttcc ttaaaggaag
    15421 cggagaaggc gctcgccagt ctgctttctg atttgtcaaa catgcccatt gtccattttc
    15481 tcaatcggga atggggtgtt cctcatgtga tacctgatat gttcaaagcg ctggaatcgt
    15541 tttatctgca tcagcaaact gatattcacg cagagaaaaa gctttatgcc cattatgtat
    15601 ccgcaatgat tattgggttg cttttgtatc ggctggatga aggaaaggcg catccgcctg
    15661 aagtgctggc gagggaattt ttgcagtttt tggatgtgaa aaagtataag gttgtattgc
    15721 tttgaaagac aaaaagagag ggacatcccc tctcttatct cgtttctttc ttccatttct
    15781 catcaatcag cattttccct ggccatgtgt atgccatgat gccgccgtct gcggtgatgt
    15841 cctctcctgt gacgtatgag ctgtcgtctg acgcgaggaa cagggccact gtcgccattt
    15901 ccttcggctg gccgaggcgg ccgagcggcg tgacccattt gttggcttcg cggaattttt
    15961 cacccatttc ttgttctttg gtgcctgcta atttgtcaat cagcggggtt tcgatcgtac
    16021 ccggtgaaat ggaattgacg cggatgccgt ttcgtgcgta gtcgattgcc attgcctttg
    16081 tcaggttggt gatgccgcct tttgctgcgt tgtagccgga gcgatcaagg tccgcggcac
    16141 ggcctgacat ggaggaggta ttgatgatgg agcctccatt ttcgagcatg agcggaatca
    16201 gatatttgct gcaaagaaat gtgccgcgca ggtcgacggc gataatgcgg tcaaacaggt
    16261 caatcggata ttcgtgcacc tttccgcctt cctgatcaac gccggcatta ttaaacagaa
    16321 tatcaatcgt tccgcatgca tccttgattt gatcagcaaa tgctttcaca ctgttttcat
    16381 ctgacacatt gaggtgaaag gattcggcct gtcctccgtt ttttctgatt gcgtcaactg
    16441 tttcttccat ttgatcttta ttgatatctc cgatgatcac acgcgcgcct tcattggcaa
    16501 aaacctctgc cgtcgcttgc ccaatgcctg tcgcggcgcc tgtgatcact gctgttttgt
    16561 tttcaagtct tcccatgata cgagacctcc tttttctatt tgtcttcccg ctatgtgcag
    16621 tgataaacat gcgagaaaag aaaggccagc atatgttaag atgaattaga aattgttggg
    16681 aggtttgtat gtttgaaggt acagcataag aaggagctca agttttattg cttcattacc
    16741 attccatctg catttgttgt gctgactgtc atctcttttt tattgcaaga gattacgttc
    16801 ccggtgactg caagcgcatt tctgaatgct tcatggcata atctattgtt tttgataccg
    16861 ttcggtttgt ttttctaccc ggtgcatata tggatgaagc gggagtttgg ccgctggaat
    16921 gacacagaaa aaaagagagg atgatgaagc ctctcttttt tatgagaatg agtgagaaaa
    16981 agagtgaaaa caaatccaac taatgttaaa tttacatata tatgcatcta tcaatctaat
    17041 tgacaattgt catcttatgt gataaataga tgctgaaaag ggtttacata atggtaaagg
    17101 agcgatcaag agtggcgaaa aaagagttta aagcagagtc taaacgcttg ctggatatga
    17161 tgattaactc catttatacc caaaaagaaa ttttcctgcg cgagttaatc tccaattcga
    17221 gtgatgcgat tgacaaaatc tattacaaag cgcttacgga cgatgcgctt acgtttgata
    17281 aagacagtta ctacataaag gtcgcagctg acaaagatgc gagaacatta accatctctg
    17341 atacggggat cggaatgaca aaggatgagc ttgaacagca tcttggaacg attgcaaaaa
    17401 gcggttccct cgcgtttaaa aaggaaaatg agctgaaaga cggacatgac attatcgggc
    17461 agttcggtgt cggtttttac gcggcattta tggttgccga tgtcgtgaca gtcatcagta
    17521 aagcgcttgg cagcgaagaa gcttataaat gggagtctgc gggtgcagac ggctatacga
    17581 ttgaaccgtg tgaaaaggat tctgtcggta cagacattat cctgaaaatc aaagagaaca
    17641 cagaagatga cagctatgac gagtttttag aggaatatcg tttaaaagcg atcatcaaga
    17701 agtactccga cttcattcgc tacccgatca aaatggatac aaccattaat aagccgaagg
    17761 aaggcagcga aaatgaattt gaagaggtgc aggaagagca gacggtcaac agcatggtgc
    17821 cgatctggag aaaaaacaaa agcgagctga cagatgagga ttatgaaaaa ttctatgctg
    17881 aaaagcatta cgggtttgat aaaccgctga cacacgttca tatcagcgtg gatggagcgg
    17941 ttcgctacaa tgcgattcta ttcatccctg aaaacatgcc gttcgactac tattccaagg
    18001 aatatgagaa aggcttggag ctgtattcca atggcgtgct gatcatgaat aagtgtgcag
    18061 atctgcttcc ggaccacttc agctttgtga agggcatggt cgattctgag gatctgtcgc
    18121 tgaatatttc cagagaaatg ctgcagcatg accgccagct gaagctgatc gcgaaaaaca
    18181 tcagcaagaa aatcaaaagc gagctgcaaa gcctgttgaa aaaagaccgc gagaaatacg
    18241 agacgttcta caagtcgttc ggcagacagc tgaaattcgg cgtgtacaat gattttggcg
    18301 cgaataagga tcaattgaag gatctcctct tattctactc ttcaaaagag aaaaaactgg
    18361 tcagcttaga cgagtatgtt tccagaatgc cagaggagca gaaattcatt tattacgcga
    18421 ccggggattc ttacgaccgc attgagaaac tgccgcaaac ggaaatggtg gcggacaaag
    18481 gctatgaaat cctctacttt actgaggaca tcgatgagtt tgcaattaaa atgctggctt
    18541 cttatcagga aaaagaattc aagtccgtat caagcggaga ccttggcata gacacggatg
    18601 aggatcaaaa gcagtccgag gaagaggaaa gcaagtataa ggatctgttt gaggaaatga
    18661 aaaacattct gtcagacaaa gtgaaaaacg tcagaatctc aaaacggctt aaatcacatc
    18721 cagtctgcct tgcagctgac ggcgaagtga caattgagat ggaaaaaatc ttaaacgcga
    18781 tgcctgacag ccaaaatgtg aaggcggaaa aagtgctgga aatcaacccg aatcacgagg
    18841 tattccaaac gctgcaggac gcgtttgaac aagataaaga gaagttgagc ctgtacacaa
    18901 accttctgta caatcaggcg cttctcatcg aaggcctgcc gattcaggac cctgtggaat
    18961 ttacgaacaa tatttgcaag gtcatggtgt aaacagaaaa aggaatcgtc ccataaggag
    19021 acgattcctt tttttataat gtacgctcat tcagcacttg gttttgggtg cttttcttct
    19081 ttttaaaccg gtttttcagg cttgcttcaa tttcctccaa gcttttccct ttggtttccg
    19141 gtaccatgta gaacgcgaag aaaaatgaga gaagacaaat gactgagaaa accataaaga
    19201 cccatgcgat gcccatcgcg cttagcatta gcgggaagac gagcgacacg atcagattgg
    19261 ccgccgataa caccaaagtc gtgaaccctg tcgcggctcc gcgcgctttg gacgggaaga
    19321 gctcaggcat gagcacccac actaccggac cccatgtcgc ctggtaaaag acgatataga
    19381 cacctagaaa gactactgtc atccacgctg ttgatgcgga aagtccgagc gttaggagca
    19441 cgcctgataa agcagcaagg ctcagtgtga tgccgacact tccccagatc agaagttttt
    19501 tgcggccgac acggtcaatt aagatcatgg cagtgataca catgatgacg ttgaggatgc
    19561 cgatccccat tgtgccgagc gccgaagctg atgtgccaag accggccttc gtaaaaatgg
    19621 ttggcgcgta gtagatgacc gtgttaatgc cgaccgcctg ctggaaaatg gcaaggccga
    19681 cgccaatcag aagcatgggg cgaatccatt tggcttttag gacgctgagt gtcgtttctt
    19741 ttttctctgc ttctccttgc ttcatctctg ccaattccat ttcgatgtct tttggatcat
    19801 gagtgatgtt catgatgcgt ctcgcttctt cttcacggcc gcgcttcacg agccatcttg
    19861 gcgattccgg catgaacgcg atgccgatta atagaagcac ggcaggcact gcggccagac
    19921 caaccatcca gcgccacgct tcaaacggtg tgaacaggta gttcacgata taggcgagca
    19981 aaattcctgt gacaatcatt aagttgttca ttgtgccgag tgtaccgcga atttttgtcg
    20041 gtgccatttc tgaaagatat acgggcacaa gcgccgttga accgccgacg gccaatccga
    20101 gaatcaccct agatgcaatc agcatgccga ttgtttgaga aaatgcgcaa gcgagcgctc
    20161 cgataatgaa aatgatggaa aggacaaata caacctttct cctgccccag cggtctgagc
    20221 atgtgccgct caaggcagaa ccgaaaatcg cgccaaggag cagcatgctg
//
