LOCUS       NZ_CP058255            23261 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Priestia megaterium strain BHS1 chromosome, complete genome.
ACCESSION   NZ_CP058255
VERSION     NZ_CP058255.1
KEYWORDS    RefSeq.
SOURCE      Priestia megaterium (Bacillus megaterium)
  ORGANISM  Priestia megaterium
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 5373548)
  AUTHORS   Vilchez,J.I., Tang,Q., Kaushal,R., Wang,W., Lv,S., He,D., Chu,Z.,
            Zhang,H., Liu,R. and Zhang,H.
  TITLE     Complete Genome Sequence of Bacillus megaterium Strain TG1-E1, a
            Plant Drought Tolerance-Enhancing Bacterium
  JOURNAL   Microbiol Resour Announc 7 (12), e00842-18 (2018)
   PUBMED   30533669
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5373548)
  AUTHORS   Abdul Wahhab,B.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2020) Bioscience, UTM, Skudai, Johor, Johor 81300,
            Malaysia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. 2019-10-29
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 18.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015582655.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 13:26:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,643
            CDSs (total)                      :: 5,510
            Genes (coding)                    :: 5,455
            CDSs (with protein)               :: 5,455
            Genes (RNA)                       :: 133
            rRNAs                             :: 8, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 117
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 16 of 55
            Pseudo Genes (incomplete)         :: 30 of 55
            Pseudo Genes (internal stop)      :: 17 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:55:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3580522
            Orig. end                         :: 3603783
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP058255.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from microbiology Lab of UTM.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23261
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="7"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23261
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23261
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13261](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13261
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            55..609
                     /locus_tag="HW369_RS18855"
     CDS             55..609
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /locus_tag="HW369_RS18855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_195694735.1"
                     /transl_table=11
                     /translation="MKLAEQIRKIRKNENLSQEQLGQKMNVTRQAIYKWESGKGYPDIQ
                     NLIMLSELFEISLDELIKGDRSLQGKIKVKGGTGMFSNRSLLSALNYFSLFFAPVVFPL
                     ITLIFGYKEMKQHGKRAFISHLIPTVTLIVIGISYYISAKLAGTQTPNSILVSGGTILI
                     ILIMFGVIIWNVKEGVKQIKA"
     CDS             625..714
                     /gene="allorf_3581147_3581236"
                     /locus_tag="allorf_3581147_3581236"
                     /protein_id="allorf_3581147_3581236"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSVLKKALTFHLSECFFSLDSSCNNDYGN"
     CDS_motif       625..678
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSVLKKALTFHLSECFFS"
                     /locus_tag="allorf_3581147_3581236_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       679..714
                     /prepeptide="core"
                     /locus_tag="allorf_3581147_3581236_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="1165.1"
                     /monoisotopic_mass="1164.4"
                     /core_sequence="LDSSCNNDYGN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSVLKKALTFHLSECFFS"
                     /leader_location="[624:678](+)"
                     /alternative_weights="1183.2"
     gene            782..1015
                     /locus_tag="HW369_RS18860"
     CDS             782..1015
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HW369_RS18860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028410408.1"
                     /transl_table=11
                     /translation="MKRAIGIFLIAQAVLTYLTIKMIYTPFIVRTLDRNTGVMTVSYSF
                     PLTYWLICIALGIMLIVGTYLVFAKEKKQIFN"
     CDS_motif       782..913
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKRAIGIFLIAQAVLTYLTIKMIYTPFIVRTLDRNTGVMTVSYS"
                     /locus_tag="HW369_RS18860_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       914..1015
                     /prepeptide="core"
                     /locus_tag="HW369_RS18860_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="3811.7"
                     /monoisotopic_mass="3809.1"
                     /core_sequence="FPLTYWLICIALGIMLIVGTYLVFAKEKKQIFN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKRAIGIFLIAQAVLTYLTIKMIYTPFIVRTLDRNTGVMTV
                     SYS"
                     /leader_location="[781:913](+)"
                     /alternative_weights="3829.7"
     gene            complement(1194..1631)
                     /locus_tag="HW369_RS18865"
     CDS             complement(1194..1631)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016130592.1"
                     /locus_tag="HW369_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_195694736.1"
                     /transl_table=11
                     /translation="MIREAEPKDSSVIEKLYKKLAPHSKNLKVLPERVEQIRKDSNNFL
                     FVYEEDHAIKGSVFITFCLDPGYEFRPYTIVEYVIVSEGYRGKGIGEKLLKHVEKVSIG
                     RESTRIVLLSSVARTEAHKFFTKNGYDGTISKGFKKYIPIV"
     gene            1948..2337
                     /locus_tag="HW369_RS18870"
     CDS             1948..2337
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060043.1"
                     /locus_tag="HW369_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_195694737.1"
                     /transl_table=11
                     /translation="MDKIKKVLVLFLAILISIIIVLSVIFINWEHIFGDTRPIANAKAM
                     YQLEFKDKDIAETTDVDNNIMYLVPKGHLDTYIEMMKKKGYTLTEKDDKHHTLLIKKGN
                     TFTEISYKSLTSRYTLISSPFLKEV"
     misc_feature    complement(2363..2381)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.07"
                     /tool="antismash"
     gene            2395..2649
                     /locus_tag="HW369_RS18875"
     CDS             2395..2649
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HW369_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_195694738.1"
                     /transl_table=11
                     /translation="MKYVDVVTESKIRGISLALLLIFMSLGWYLNSSVWYEAAILVVSI
                     AFILHAVNYYLTTKNKATGITAIAASSGFGLYNLLSIFF"
     gene            2693..3883
                     /gene="ftsW"
                     /locus_tag="HW369_RS18880"
     CDS             2693..3883
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsW"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016766252.1"
                     /locus_tag="HW369_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative lipid II flippase FtsW"
                     /protein_id="WP_195694739.1"
                     /transl_table=11
                     /translation="MFKKIIRCYDYKFIAALVVLCLIGLVMVYSASMITAISRYGVEGD
                     YFYQKQKLALIAGFFLFCMAAFVPYKIYQEKKVLKILLATVIILLVLVLIVGHTAGNAQ
                     SWLILGPIRIQPLELAKLAIILYLSAVFTNKQEYINDLKRSVIPPMLIVFFICFLIAMQ
                     PDYGGILLILGIVAAIVLCSGISKKSMIKIALLGVIGVIIMLFVLLITGHIATVFSPVR
                     LARFTGFLHPFANQQGDGYQLVNSYLAIGTGGLTGQGLGQGVQKAGYLPESHTDFIMAV
                     IAEELGFWGVLLVLGLLFFIIIQGLKIARKCNDPFGALLAIGISVMIGIQAFVNLGAVT
                     GILPITGVTLPFVSFGGSSLTLLMLAIGVLTNISMFTNYERKYKNKVTKQNKLKSV"
     CDS             complement(4888..5118)
                     /gene="allorf_3585410_3585640"
                     /locus_tag="allorf_3585410_3585640"
                     /protein_id="allorf_3585410_3585640"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSFPSYKSHALNKKELLEILYIICKINSICYIYEIYRYFLLFYIN
                     NFNILMKILKPVTLYGRRMSAENSLYYTYIR"
     CDS_motif       complement(5053..5118)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSFPSYKSHALNKKELLEILYI"
                     /locus_tag="allorf_3585410_3585640_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4888..5052)
                     /prepeptide="core"
                     /locus_tag="allorf_3585410_3585640_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="6629.9"
                     /monoisotopic_mass="6625.5"
                     /core_sequence="ICKINSICYIYEIYRYFLLFYINNFNILMKILKPVTLYGRRMS
                     AENSLYYTYIR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSFPSYKSHALNKKELLEILYI"
                     /leader_location="[5052:5118](-)"
                     /alternative_weights="6647.9"
                     /alternative_weights="6665.9"
                     /alternative_weights="6683.9"
     gene            5361..5780
                     /locus_tag="HW369_RS18885"
     CDS             5361..5780
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /locus_tag="HW369_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_195694740.1"
                     /transl_table=11
                     /translation="MSNQTTFIDKEKKLPINNADLKICIKYKGTINIINLNEISYIERV
                     GRKTFIHLSDGNQITCNESLKSLNNILENYGFYRIHQSFIVAIDKIKKVEVDHNGRDYI
                     VNMQSHNSPVWLSKYKYQQLKALLWKNSIFGISMN"
     gene            complement(5923..6192)
                     /locus_tag="HW369_RS18890"
     CDS             complement(5923..6192)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HW369_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_195694741.1"
                     /transl_table=11
                     /translation="MKKWILVIIMAILGCSSVFNYFYMNNLSTSSEEVKVYLVPFLISA
                     VVKHDMLEKLSTFYLFGGIFIIVLSILFTLLMLKKNKRVHSRQA"
     gene            complement(6253..6981)
                     /locus_tag="HW369_RS18895"
     CDS             complement(6253..6981)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="HW369_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_195694742.1"
                     /transl_table=11
                     /translation="MEILMLINGIKIEFLKLKRTGIYWFIYIIPAIFTIVNGILYAGSS
                     KQGYEILRAVTFQIFLTFLYPLLIGVITALLIRMERKDYGLNNQLILPISRTRVYLNKL
                     VLLVFLNLMIVITIYLVLAIYTLVFQAKGYSLLEEIPHFVCIWLSGCLISSIQLLLSFQ
                     FSGVLVPIAFCTILTMTGMFASAQKTLSMIDFWTYPVLSAFNGYNLFLIGTVSFILTCL
                     FTILGMYLFKNKWINQIGKQ"
     gene            complement(6986..7693)
                     /locus_tag="HW369_RS18900"
     CDS             complement(6986..7693)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="HW369_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_195694743.1"
                     /transl_table=11
                     /translation="MYLDLFKSELHKLKRNKIWYSVFLLPIFSVGLQFCIFFYKEKTME
                     ITWNEYVTWNHSFFPCFLYIFISIFYYTVINNEYNNSTWRVIFITPVARTHIFIVKWLV
                     GNILMLISLIIGTFLVFITALFLQISDISVIKLFYFPLYLWLGAQGMIAIFSMLSIIIK
                     NGVISISIGIVSSLLYLQNSNQKLLPISYPAWVIGPDASYSIHYLVPYMSMSLIVTIFA
                     ILMGIFSVNKKDF"
     gene            complement(7693..8610)
                     /locus_tag="HW369_RS18905"
     CDS             complement(7693..8610)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003347962.1"
                     /locus_tag="HW369_RS18905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_195697087.1"
                     /transl_table=11
                     /translation="MMEQIIRTENLTKKYGDHTIVDSLNLDIKEGQIYGFLGPNGAGKT
                     TTIRMLLSLIAPSSGKIEIFGLNLNEHRKKILNQLGAFVDSPYYYGHLTGYENLDVIQK
                     MLGRDTGKILKVLETVGLNQAQDKLVKTYSLGMRQRLGLAFALLNEPKLLILDEPTNGL
                     DPAGIHEIRELLKSLARDKGYTIFLSSHNLNEIELIATHVGMIQNGKMIYQGTLEKVLS
                     QGDYQIEIGTTDNLQASSQLNKHGYSTTKRGNLLLTSGSSEDIINMNKLLVNEGIGVDH
                     LYHKKSTLEDIFLSLTSHKKEEIK"
     gene            complement(8610..8855)
                     /locus_tag="HW369_RS18910"
     CDS             complement(8610..8855)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013144000.1"
                     /locus_tag="HW369_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_195694744.1"
                     /transl_table=11
                     /translation="MIRVNLDVMLAKRKLSMTVLSQKVGITLANLSILKNEKAKAIRFT
                     TLEAICRELNCQPGDILEYIENDMETVNSLDERERY"
     gene            complement(8869..9402)
                     /locus_tag="HW369_RS18915"
     CDS             complement(8869..9402)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022636.4"
                     /locus_tag="HW369_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2975 domain-containing protein"
                     /protein_id="WP_195694745.1"
                     /transl_table=11
                     /translation="MDNRSKFYRFMYITLLICTILSILRIIWLIQYYFWDPTKYGMSSK
                     IAINTFSFMISNFEWSDGIVSLIIIQSLIVSFLLWKTCIFFKNISEEKIFVIQNAKAII
                     HSGIALGLAAFFTNIPSLMLSMKLLPYISFSEGEILVDYHFNIELFVASIAVLVLGMIF
                     RKAVYIAQENEFTI"
     gene            9731..9901
                     /locus_tag="HW369_RS18920"
     CDS             9731..9901
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016486.4"
                     /locus_tag="HW369_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type A2 lanthipeptide"
                     /protein_id="WP_211110571.1"
                     /sec_met_domain="L_biotic_A (E-value: 2e-10, bitscore:
                     38.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFEMMAMAAIEDVQDSELEQLTGGQVPTITKDCPNTVSSVCVT
                     FPFISACKNCD"
     CDS_motif       9731..9808
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNFEMMAMAAIEDVQDSELEQLTGG"
                     /locus_tag="HW369_RS18920_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9809..9901
                     /prepeptide="core"
                     /locus_tag="HW369_RS18920_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="1.90"
                     /molecular_weight="3092.6"
                     /monoisotopic_mass="3090.5"
                     /core_sequence="QVPTITKDCPNTVSSVCVTFPFISACKNCD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNFEMMAMAAIEDVQDSELEQLTGG"
                     /leader_location="[9730:9808](+)"
                     /alternative_weights="3110.6"
                     /alternative_weights="3128.6"
                     /alternative_weights="3146.6"
     gene            10001..13261
                     /locus_tag="HW369_RS18925"
     CDS             10001..13261
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="HW369_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_195694746.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-101, bitscore:
                     339.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.3e-69, bitscore:
                     230.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQIYNFPYQEWARALYLHERKGIDTSKLTIKINEINLWKQRAGF
                     FTYELYKHRVNEDLLTLDEWKTLASNPQVTPHISYIPKWMKDLEEAINNTYFIELNSDD
                     FLKESIFKKPFFEFAIPFLKYTKYKIIQKIQENSTLNTLLSEDKVLIQSILSPLAEQIL
                     KISSKTLIYELNKERLQGHLVGQTREERYRFFIATKFNNSASFSQLLDEYPVLGRLISE
                     KMNFLYNSIFNALNDWILDREKVIKEFSGTFQSIARLDLMGDVHNAGKAVLKFTFTDNT
                     SIIYKPRPLSIDVHFQQLLQWVNKKGISDSFNTLKVVDCKDHGWVEYVEHRPCSTMDEV
                     NNFYKRQGRYLAILYMLNATDFHYENIIACGEHPYLIDLESLFHHSTSKKDKIATATQK
                     AEELLDNSVIGTTLLPVRINNPRFAEANFSGLGNNEGIVVTSVIENSHTDEMCMKKKTL
                     LIKPEVTHLPSYKGMPISYEQFTSYIIEGFTEVYKIFMEEKETLLSEDGPIYKFEKDKI
                     RIILRPTYYYGRILESSKHPKYLKNGIDRVQLFDLLWRATADIPNLYKVVHSECQDLLQ
                     EDVPYLYTSVNSRNIRDCREKCIEDFFNETPLERVINKIENICLTDLEQQIEFINASFH
                     SNQLEETNPIDKLETLMSKEQDKEELFKVDKNHLNKSILEEAKRIGEEIADLAIWSDDK
                     NTITWLSMGVTRLGNIEYSVMKLGLYSGILGMALFYAYLYKITNIPKFKDISQASVNTA
                     LKDYIHGKQDGQEDHSAYLGYAGAIYVFMHLHSVFKRPDLIEEADKLLNRIEELIDHDS
                     QFDILSGNAGLIPICLDFYEMTGNKKAFYIAKRCGDVLLNHSHNDKGNIYWRSQDMPLD
                     KPPLTGFSHGTAGIAWALTKLYKITNEVKYLEHAMGAIRYENLSFNPKYNNWANYSNTQ
                     RLQEDKVYSVSWCNGATGIGLSRMKIAKLIPENVQIQKDLYSALDSVLKNGLIKDSHCL
                     CHGQLGSLEFLYRGAEAIENKDLLEEVYKHLFKLMQQTKDSQWWECGFANKYVTPNLMV
                     GLAGVGYQLMRFYQPNIPSVLTLEPPQYIAKEVSMNDE"
     gene            13251..15446
                     /locus_tag="HW369_RS18930"
     CDS             13251..15446
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="HW369_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_195694747.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5e-36, bitscore:
                     121.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSNQIIEHKRSVPYIRQLEKSECGLTCLAMVLSYYNHEVELFRL
                     RNHISGGRNGISLLTLKKLAISFNLDSQGKKGSVDVLHSIPHPVICYWDNSHYVVLEKI
                     SDKFFFIVDPSLGKMKLTLEEFRSKYSGYFLTMKPTEKFIKKKKEKNILWSYLKPFLYE
                     RKILATIILFAFLLQLISICIPMLSKYVVDKASISKQLNIVHIVGVAMISAVILQITFR
                     YIHGYMLIILQNKLDKKLIERFISHLFSLPLRFFQVRSNGDLVMRSHNIEILRELIVNH
                     LVSTIINVFVLAFMFVYMLSQSISLSLGLLAIGIFQVMFTLITRNKMKNLSTQEIASTA
                     ALRSYLTESIQGISLIKNVGIEEHIIHKWSNLFDKKLENAYQKNKVNLSIESVLQSIQL
                     LVPALIIWIGTYQLIQGQISIGTLFAFQSLSISFLTPINSLASSITALTQMETILDLIM
                     DVERTKKEDTSGKSFENLKGNITLNNVSFQFDAHSPLALKNINLEIPHGKKVAIIGESG
                     SGKSTLISLLNGLFEPTQGTIYYDKYNMADLDKKLLRSQLGIVTQNHILFNQTIRENIS
                     LGNPDLDYSDIIISAQLAEIHDDIMKMPMQYETIISENGTNLSGGQKQRLSIARALINQ
                     PKILILDEATSALDTVTEEKVDANISSMNCTRIVVAHRLSTIINSDMVVILKDGQIVAN
                     GTHKQLEKNPEYLKFFKKQQRDEFDTEQIKHLQKVSN"
     gene            complement(16292..16561)
                     /locus_tag="HW369_RS18940"
     CDS             complement(16292..16561)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013060102.1"
                     /locus_tag="HW369_RS18940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_195694749.1"
                     /transl_table=11
                     /translation="MLKKMKNYEKAITVEGKHKRQTQQEMNELQRDMKYQVEEEKADTE
                     SKIAMKKDAIQSSDASIQLYKDEQKSLQEKLQKLNEKQQDLAMK"
     gene            complement(16641..16799)
                     /locus_tag="HW369_RS18945"
     CDS             complement(16641..16799)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HW369_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_195694750.1"
                     /transl_table=11
                     /translation="MSSNWDALAFDPYQENEEKETVNVDDVTSDSEPDSTEGIDAQALI
                     TTIYSDQ"
     misc_feature    complement(16758..16771)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: strong, score: 23.52"
                     /tool="antismash"
     gene            complement(16834..17028)
                     /locus_tag="HW369_RS18950"
     CDS             complement(16834..17028)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HW369_RS18950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_195694751.1"
                     /transl_table=11
                     /translation="MQPHKSMKYMVAEKQVLIPLSACFFIIIFLTLNFLFNTLRQLIQT
                     TFSDVFDSKPFHLSLSFII"
     gene            complement(17015..17524)
                     /locus_tag="HW369_RS18955"
     CDS             complement(17015..17524)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HW369_RS18955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_195694752.1"
                     /transl_table=11
                     /translation="MYNQRQAKNQRHSFVVGVEYRHEDIFVEVELGKFRTTPLHAQRIA
                     NSVNSIILLKNHMVIIFKNAKSITISDDFLKQEYQFRICIKPAMRPLDSSALTHQERED
                     FTQNQSYIVPEENMKEMNWDFQIAFQYLQDRYDAHDRTHFSFSQSSFYIIPVSEQKQEE
                     VQHATS"
     misc_feature    17697..17706
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     CDS             complement(17754..17867)
                     /gene="allorf_3598276_3598389"
                     /locus_tag="allorf_3598276_3598389"
                     /protein_id="allorf_3598276_3598389"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPKTLRIIELSESYACQYRVCPSSQKRVPISFSYVKR"
     CDS_motif       complement(17820..17867)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPKTLRIIELSESYAC"
                     /locus_tag="allorf_3598276_3598389_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17754..17819)
                     /prepeptide="core"
                     /locus_tag="allorf_3598276_3598389_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="2456.8"
                     /monoisotopic_mass="2455.3"
                     /core_sequence="QYRVCPSSQKRVPISFSYVKR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPKTLRIIELSESYAC"
                     /leader_location="[17819:17867](-)"
                     /alternative_weights="2474.9"
                     /alternative_weights="2492.9"
                     /alternative_weights="2510.9"
     CDS             complement(18107..18274)
                     /gene="allorf_3598629_3598796"
                     /locus_tag="allorf_3598629_3598796"
                     /protein_id="allorf_3598629_3598796"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MYGHFFYLSTKVYSLQAKKTINFSAFLKKYYKKTHYPGHVRDCTI
                     IINRCYLISS"
     CDS_motif       complement(18203..18274)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MYGHFFYLSTKVYSLQAKKTINFS"
                     /locus_tag="allorf_3598629_3598796_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18107..18202)
                     /prepeptide="core"
                     /locus_tag="allorf_3598629_3598796_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="3660.3"
                     /monoisotopic_mass="3658.0"
                     /core_sequence="AFLKKYYKKTHYPGHVRDCTIIINRCYLISS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MYGHFFYLSTKVYSLQAKKTINFS"
                     /leader_location="[18202:18274](-)"
                     /alternative_weights="3678.3"
                     /alternative_weights="3696.3"
     gene            complement(18279..18935)
                     /locus_tag="HW369_RS18960"
     CDS             complement(18279..18935)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="HW369_RS18960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_171776407.1"
                     /transl_table=11
                     /translation="MSDLSKPIKVVLIEDDLEWLHSIQTIIKAEKDIELVGYGSTEEDT
                     LRLARDIDKVDIFLVDINLTGAKLDGIHAAYELKKMQSIDNSKWKVIMLTCLSEKDVII
                     KAFAAGAVNYILKKDMHNIANIIRSTYVGNFTAIEAMLEDYRDLKYEQQLTNLTQSERV
                     VFNMLEKGYSRQSMQEELSKSKNTIKNQIQSIFKKLSVRNIKDAIEKAKSGGLEK"
     gene            complement(18939..20312)
                     /locus_tag="HW369_RS18965"
     CDS             complement(18939..20312)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="HW369_RS18965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_195694753.1"
                     /transl_table=11
                     /translation="MVALFVISGLFALICYCYDPKYPPLRWMTLLLACASSAGLSRAII
                     ESFIPILNMHHMNFNWLNTFLYYARIITGFFSIYFCPWGVLMHAIVYSERFSNKTINNL
                     KYILFTPIIVMIFTTTYVPDIVPDFKGLFYWGVPYIITGYIIHLYSYFTESDPYKKKTR
                     FITFTIMHPIMLSALILNYIVRVFDNHHEYWRYVIVFMLISFSYFIWRAFKQDGVGSMN
                     GIKIKYEKQTQIKANKAILTGVSLMNHAIKNQIFRIVTGMKLIKENTSELNHLSAEGIN
                     MVDSGSDHLLKMVEKINSKTQDITIVKKRNNLTEVVDGVISELEVEFVENHIVITKEYL
                     DEDVYAFFDKTPTKEVFLNMFKNAIEAIEKEGIINVRINKKGKKAVVIISDNGIGITKE
                     NLEYVKSPFFTTKKLKDGNTGWGLYYCYDVMVKSDGNLEISSQVNVGTDIKLTFSTKR"
     gene            complement(20312..20944)
                     /locus_tag="HW369_RS18970"
     CDS             complement(20312..20944)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /locus_tag="HW369_RS18970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD hydrolase-like protein"
                     /protein_id="WP_071277399.1"
                     /sec_met_domain="HAD_2 (E-value: 5.2e-31, bitscore: 106.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTVICDFDGTIVNSAQLVYDLFNSFSDKYSYEKMPQEKMDYIR
                     SITFRQRFKEYNVSFFKVPSLVMDVVKEYKKSVPYLQVNSEMKEVLRELKNREFKLVLI
                     SANSKENIEKFLKLNDMEYFDEIIRSKRFFGRNLTINSYIKSHNLRRDETILIGDEHRD
                     IIASKKSNIKIVSVTWGYDLEELLITGRPDYLVKCPNQILNVIDGVT"
     CDS             complement(21256..21426)
                     /gene="allorf_3601778_3601948"
                     /locus_tag="allorf_3601778_3601948"
                     /protein_id="allorf_3601778_3601948"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGSVNFYSLFFVKVLSFIVYFLIKTTKLSADKGGDTVIGDIKNCE
                     VVTLFENTIYF"
     CDS_motif       complement(21307..21426)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MGSVNFYSLFFVKVLSFIVYFLIKTTKLSADKGGDTVIGD"
                     /locus_tag="allorf_3601778_3601948_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21256..21306)
                     /prepeptide="core"
                     /locus_tag="allorf_3601778_3601948_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1897.2"
                     /monoisotopic_mass="1896.0"
                     /core_sequence="IKNCEVVTLFENTIYF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGSVNFYSLFFVKVLSFIVYFLIKTTKLSADKGGDTVIGD"
                     /leader_location="[21306:21426](-)"
                     /alternative_weights="1915.2"
     misc_feature    complement(21284..21296)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    21462..21475
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.65"
                     /tool="antismash"
     gene            21873..23156
                     /locus_tag="HW369_RS18975"
     CDS             21873..23156
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106145.1"
                     /locus_tag="HW369_RS18975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="replication protein"
                     /protein_id="WP_195694754.1"
                     /transl_table=11
                     /translation="MTKILTCYLPDVNTFNGRFKWLWKEKPTLRKKKEAFLETLRTYFK
                     QQQEALHKVFPKKRMEMLDYVIYNLVATGIQAIQSKTLMQKFDVSQSTVSRFVKSLKET
                     PFMLVARYIKEDATGAHPDSYVFILKSHKNFDQICEEIFFAHDTTGIQTLQQEEMTTPV
                     TTPVTTPECAENVDTTSFEGEKTSSPFINLDLPKNHLNNHLISASQSFAYIKGVPKKVN
                     HVYAGKYGHQLKDFYARIRNAAKAVKRDTKIEIVKEQVHEVAYTAIVGLDKYVHEANHK
                     GTPLSLDDMCRLVYQIAHNQFTNLLKGNTEEPSSKSDIHTEAETALYTPKQIIRKELVP
                     AWLQAEQEQKECTQEPALSLDEQLEMIQLKQDLGQELTPEEETLLQEQSTTYSSLEMAQ
                     LKQDLGQALTPEEQALLHEHAQLQDTVS"
ORIGIN
        1 ttatcgcttt atagtaatta aaatcataaa ctaaatgtga aggaggcagc taagatgaaa
       61 cttgctgaac aaattagaaa gatacgtaaa aacgaaaatc tttcacaaga gcagttaggc
      121 caaaaaatga atgttaccag acaagcaatt tataaatggg aaagtggaaa aggataccct
      181 gacattcaaa atctaattat gctaagtgaa ctatttgaaa ttagtcttga tgagttaata
      241 aaaggagatc gttctttgca aggtaagatt aaagtaaagg gaggaacagg tatgttttct
      301 aatcgtagtc ttttgtctgc attaaactat ttcagtttgt tttttgcccc agttgttttt
      361 ccacttatta cactaatatt tggctataaa gaaatgaagc agcatggaaa aagagccttt
      421 atatctcatt tgataccaac tgtgaccctt atcgtaatag gaattagtta ttacatatct
      481 gcaaaactag ctggaacaca gacacctaat tccatattag ttagtggtgg taccattttg
      541 attattctaa ttatgtttgg tgttattata tggaacgtaa aagaaggggt taagcagata
      601 aaagcataag tatttaatca tgaattgtca gttttaaaaa aagcactcac ctttcattta
      661 agtgagtgct ttttttcttt agatagttct tgtaataacg attatggtaa ttaacattaa
      721 taagtaagcc tatttatgtt aaattgtaca tagaaacatg tatgagtctg gaggcaaggt
      781 gatgaaacgt gcaataggga tatttcttat tgctcaagct gtattaacgt acttaactat
      841 taagatgatt tatactcctt ttatcgttag aacattggat agaaatactg gagttatgac
      901 agtttcatat agtttccctt taacgtactg gttaatttgc atagctttgg gcattatgct
      961 tatagtggga acgtatttag tttttgctaa agaaaagaag cagatcttta attaaaggtc
     1021 tgctttttat ttctaccgat aaacggtttt atgttaactg gaatatatga ttcatatact
     1081 aaccatatta gataaaaata aatgttaaga gctcttctag aaagaagaac acctcaaaaa
     1141 tcctgtttca tttctaagaa aataaacagg atttttgagt gagaatatag tcgttaaaca
     1201 atgggaatgt atttcttaaa acctttacta atcgttccat cgtaaccatt tttagtgaag
     1261 aatttatgtg cttctgttct ggctacgcta cttaataaga caattcgtgt ggattccctt
     1321 ccaattgata ctttttctac atgttttaat aacttctccc ctatcccttt tcccctgtaa
     1381 ccttcactca caattacata ttctacaatt gtataaggtc taaactcata tcccggatca
     1441 agacagaaag ttataaatac acttccttta atagcatgat cttcctcata cacaaataag
     1501 aaattattag agtcttttct tatttgttca accctttctg gtaaaacctt gagattttta
     1561 ctatgaggcg ctaatttttt atatagcttc tcaattacac tactgtcttt tggctcagct
     1621 tcacgaatca tgtaattacc tatctttcta ttattaattt atcttgtcac tacattacca
     1681 ttaaattcct tattatgtaa ataaactaat gaattacact atgttaaaat taggcatacg
     1741 tttgggttta ttttcaaaat ataaatttaa atatttacta atttatgtaa taattgtata
     1801 tattcattgc ctaaatgacc ttagtaagta actctagcta tgcattttag aaatatactt
     1861 tagaaacaaa ttcaaagaca aagcgttaaa aaggatgtta gtaagaagaa aaagtgaaaa
     1921 ggaatcatct ctgaaaggaa cgaaataatg gataaaataa aaaaggtttt ggtgttgttt
     1981 ctagctatcc ttatatcaat tattatcgta ctctccgtta tctttattaa ctgggagcat
     2041 atctttggtg acaccagacc tatagcaaat gctaaagcga tgtaccaatt agaatttaaa
     2101 gataaagata tagctgaaac gacagatgtt gataataata taatgtattt agtacctaaa
     2161 ggacatttag atacgtacat cgaaatgatg aaaaagaaag ggtacacctt aacagaaaaa
     2221 gacgataaac atcacacact tttaataaaa aaaggaaata ctttcacaga aatctcttat
     2281 aagagtctta cttctagata taccttaata agtagccctt ttctaaagga agtttaacta
     2341 tttactagca ccaaagtaga taaatgtaat tctatagagt aataggagtg ttatatgaag
     2401 tacgtagatg ttgttacaga aagtaaaata agaggtatct ctttagccct tcttcttatt
     2461 tttatgagct tagggtggta tctaaatagt tctgtttggt acgaagcagc catccttgtt
     2521 gtctccattg cttttatact acatgctgta aactattatt taactacaaa aaataaagca
     2581 acagggatta cggcaatagc agcaagctcg ggatttggtt tatataattt attgagtatc
     2641 tttttttgaa agaactataa ttctctatat ttgcaagaaa tgaggaagtt ttatgtttaa
     2701 gaaaattata aggtgttacg attacaagtt cattgcagct ttagttgttc tatgccttat
     2761 cggtttagtg atggtctaca gtgcaagcat gataactgct attagtcgat atggagtgga
     2821 aggagattac ttttatcaaa agcaaaaact tgctcttata gcagggtttt tccttttctg
     2881 tatggcagcc tttgtgcctt ataaaattta tcaagagaaa aaagtgttga aaattttact
     2941 agcaacagtg attattctcc ttgtgttggt acttatcgtt ggacacacag caggaaatgc
     3001 acaaagttgg cttatactgg gcccaattag aatacagcca ctagaattag ctaaactagc
     3061 catcattttg tatctgtcag ccgtctttac gaataagcaa gagtatataa acgacttaaa
     3121 gcgctctgtt attccgccta tgcttattgt attttttatt tgcttcttaa ttgctatgca
     3181 accggactat ggtggaattc tccttatttt gggtatcgtc gcagctatcg tcttatgttc
     3241 aggtatctca aaaaaatcaa tgataaagat tgctttactc ggagtaatag gtgttatcat
     3301 tatgctattc gttttattaa taacaggaca tattgctacc gtcttttctc ctgttcgttt
     3361 agctcgtttc acgggttttc tccatccttt tgcgaatcag caaggagatg gataccaact
     3421 ggttaactcc tacttggcta taggaactgg ggggttaaca ggacaagggt tgggacaagg
     3481 ggttcaaaaa gctggttatc taccggaatc tcacacagat tttataatgg cggttattgc
     3541 cgaggaatta ggtttttggg gagtgctcct tgtcttaggc ttactatttt tcattattat
     3601 acaaggtcta aaaatagcaa gaaagtgtaa cgatccattt ggagcattat tagctatagg
     3661 tatttcggtt atgattggta ttcaagcatt tgttaacctt ggagcagtaa caggtattct
     3721 tcctatcaca ggtgtaacat taccttttgt aagctttggt ggttcttccc tcacattatt
     3781 gatgttagca ataggagtat taacaaatat ctcgatgttt actaattacg aaagaaaata
     3841 taaaaataaa gtgactaaac aaaataagtt aaaaagtgtt taaagttttg aaaagtggca
     3901 gcttagtatg agaagttgcc actttttgtt tccgataact cgtaaccttg cttataatac
     3961 acggagctta ataaaaaaga atcctatgcg agtatgcaaa ggattttcaa atttattgga
     4021 atagggggaa tacgttatta gtttggccag atttgtagat tcatatatat atctttaaaa
     4081 ataaatattg tgtttgaatc ccctcttata aaataatttc acttaagtta tgttgttagt
     4141 taagtaaata ttaaattatt ttatttatta ttaaggtttt actatttaca cttagtgacg
     4201 acaaataatt ggattttcct cgttaaatat atgtataaat gattttcttt gacgatatag
     4261 ctaacatgtc cataacatct tcaatggcaa tgattttatt aggattatca atcatataac
     4321 acgctacatt tcttcatatt acatgataat ctattatatt atattaatac aaagttaaag
     4381 attaaaagtt tttatagtag atatgtaaat gatataactg acttataaaa agttaagttg
     4441 tatcatttac tctaattgac gacaaatacg cagtttttct acaaggtata taaatgataa
     4501 cactatttct aataaagtat gttcatcatt acttaacagt atgacaaaaa gtgaaactaa
     4561 acataatcac aattatgtta aataaaaatg ttctttataa aaactctttc ctttttatat
     4621 ttttatagga aacaagaaag aacctttcaa atagaaaaat tccttcctgt aacattcatt
     4681 tataaataat aagcctatac aattgatgat cttgacatgt agaaaaatgc tctctgatgc
     4741 aattaaattt tgttttgcgt ataaatgctc attcggtgca aatttcagcg ttctaaaaac
     4801 ttttgttttc ttgctatcat gtattaaaaa aagcttgcta tctatagtaa gctctcataa
     4861 ttcaccacta taagaaggga taaattctca acggatgtat gtgtaatata aactgttttc
     4921 agcagacatt cgtcgtccat ataatgttac tggcttcaat atcttcatta gaatattgaa
     4981 gttattaata taaaaaagta aaaagtacct ataaatttca tatatataac aaattgagtt
     5041 aattttacat atgatgtata atatttctaa tagttctttt ttattaagtg catgactttt
     5101 gtaagaggga aatgacaaaa aactaattgc aactagattt ctaatattta agaaagagag
     5161 tgaatgataa acataaataa atttaaaaaa ttgcccttcg cttagagtat atagctataa
     5221 tttcaaagaa aatccatcat atatattata aaaaatagat cttttagtta aatttacatt
     5281 taaaatcact aactgcaaat aaagaaccag gaatattact caggtaatta cgactagttt
     5341 aaaggagtgc aatgcgacta atgagtaatc agactacctt tatagataaa gagaaaaaat
     5401 tacctattaa caatgctgat ttaaagatat gcattaaata taaagggact ataaatatca
     5461 taaatcttaa tgaaatctca tacatagaac gggtaggaag aaaaaccttt atacatctct
     5521 ctgatggtaa tcaaattaca tgtaatgaat cacttaaaag tctaaacaac attcttgaga
     5581 attatggttt ttacagaata catcaatcct tcatcgtagc tatagataag attaaaaaag
     5641 ttgaagttga tcataatggc agagattata tagttaacat gcaatctcac aattcacctg
     5701 tatggttaag caagtataag tatcagcagc tcaaggcact actttggaaa aactcgattt
     5761 ttggtatttc aatgaactaa atatgttata tactctatta cccgtgcaat gagtaaatat
     5821 tatttaaatt tacacaataa ttaataaata ttccctctat attagaatta actaattaga
     5881 aacagtgcat gatatcaaat gcctatttct aattagttcc ctttatgctt gacgagaatg
     5941 taccctttta tttttcttta acattaaaag agtgaagagg atagatagaa ctataataaa
     6001 aattccccca aaaagataaa atgtagaaag cttttctaac atgtcatgct ttactactgc
     6061 gctaattaaa aaaggtacta aatatacttt tacctcttca ctacttgtgg aaagattatt
     6121 catgtaaaaa taattaaata ctgaagagca accaagaatc gccataatta taaccagaat
     6181 ccattttttc atattatcgt tcctttcatc gtataaattg tttttttaca tctaattact
     6241 tattaactaa atctattgct ttcctatttg atttatccac ttattcttaa ataaatacat
     6301 tcctaatata gtaaacaaac aagtaagtat gaaagatacg gtccctatta aaaataagtt
     6361 ataaccatta aatgctgaaa gaacagggta tgtccaaaaa tcaatcatac tcaaggtttt
     6421 ttgagcactg gcaaacattc cggtcattgt tagtattgtg caaaatgcaa taggaactag
     6481 tacaccagaa aattgaaaac ttaataacaa ctgaatcgaa ctaataaggc agccggaaag
     6541 ccatatacaa acaaagtgag gaatctcttc tagtaatgaa taaccttttg cttgaaatac
     6601 taaagtataa atggctagta caagataaat agttataaca atcattaagt ttaaaaatac
     6661 taataatact aatttgttaa gatagactcg tgttctagag attggcaaaa taagttgatt
     6721 gtttaaacca taatcttttc tttccatcct tataagaaga gctgtaatca ctccaattag
     6781 taacgggtaa agaaaagtta aaaaaatttg aaaagttaca gcccttagaa tctcataccc
     6841 ttgttttgaa gatcccgcat ataatatacc atttactata gtaaatatag cgggaataat
     6901 atatataaac caatatatac ccgtccgttt aagctttaaa aattctattt ttatcccatt
     6961 gataagcatt aatatctcca cactcctaga agtctttttt attaactgag aatatcccca
     7021 taagtattgc aaaaatagta actatgagtg acatagacat atatggtacc agataatgaa
     7081 tactgtaact tgcatcagga ccaattaccc acgcaggata tgatatagga agtaattttt
     7141 gattactatt ctgtaagtat aagagtgaag aaacgattcc aatagaaata gatataactc
     7201 catttttaat tatgatagat aacatagaaa atatagctat cataccttga gccccaagcc
     7261 ataagtataa tggaaagtaa aaaagtttaa taactgatat atcagaaatt tgcagaaata
     7321 aagcagttat aaaaaccaag aaagttccta ttattaaact tataagcata agtatgtttc
     7381 caacgagcca cttaactata aatatatgtg ttcttgcaac tggagtaata aatattactc
     7441 tccaggtgct gttattatat tcattattta ttactgtata atagaaaatg gatataaata
     7501 tgtataaaaa gcaaggaaag aaggaatgat tccaagtcac atattcattc caagttattt
     7561 ccattgtttt ttctttataa aaaaatatac aaaattgtag tcctaccgaa aatataggga
     7621 gaaggaaaac agaataccat attttgttac gttttaattt atgtaattca gacttaaaga
     7681 gatcgagata cattatttta tctcctcttt tttatgactt gttaaggata agaaaatatc
     7741 ttccaaggta cttttcttat gataaagatg gtctactcca attccttcat taacaagtaa
     7801 tttattcata ttaataatat cttctgagga accacttgta agaagtaaat ttcccctctt
     7861 agtagtgcta tatccatgct tattaagttg agaactagct tgtagattat cagtagtgcc
     7921 aatctctatt tgataatctc cttgagataa cactttttct aaagtaccct gataaatcat
     7981 ttttccattc tggatcattc caacatgggt agcaattaat tctatttcat ttaaattatg
     8041 actagataaa aatattgtat accctttatc tcttgctaaa ctcttgagta attctctaat
     8101 ctcatgaata cctgcaggat ctaacccgtt agtgggctca tctaatataa gaagctttgg
     8161 ttcatttaat agagcaaagg ctaatcctag tcgttgtctc atgcccagag agtatgtttt
     8221 aaccaatttg tcctgcgcct gatttagccc aactgtttcc aaaaccttta atatctttcc
     8281 agtgtctctt cctagcattt tttgtattac atctaaattc tcatatcctg taagatggcc
     8341 ataatagtat ggtgaatcaa caaatgctcc caattggtta agtatttttt ttcgatgttc
     8401 attcaaatta agtccaaata tctcaatttt tccactactc ggtgcaatca agctcaataa
     8461 catacgaata gtagtagttt tcccagcccc attaggacca agaaaaccat atatttgccc
     8521 ttccttgata tctaaattta aactatcaac aatagtatga tccccgtact tcttagttaa
     8581 attctctgtg cgaataatct gttccataat tagtatcttt ccctctcatc taagctatta
     8641 acagtttcca tatcattctc tatatattca agaatatctc caggttgaca gttcaactct
     8701 ctacaaatag cttctaaagt cgtgaagcga atagcttttg ctttttcatt cttaagaatt
     8761 gacaaattag ctaatgtaat tcccactttc tgcgataata ctgtcatcga caactttctt
     8821 ttagcgagca tgacatctaa atttactctt atcatgtatt atatgctcct atattgtaaa
     8881 ttcattctct tgtgctatat atacagcttt tctaaatatc attcctaata ctagtacagc
     8941 tatagaagct acaaataatt caatattaaa atggtagtct accagaatct ccccttcaga
     9001 aaaggaaata taaggtaaaa gtttcataga aagcattaaa gaaggaatat ttgtaaaaaa
     9061 ggcagcaaga cctagtgcta tgccactatg tataatggct tttgcatttt gtattacaaa
     9121 tattttctct tcagatatat ttttaaaaaa tatacatgtt ttccaaagca gaaacgacac
     9181 tattaaagat tgaataatta ttaaagaaac tattccgtca gaccattcaa agttcgaaat
     9241 catgaatgaa aaggtattga tagcgatttt actcgacata ccatatttgg taggatccca
     9301 gaaataatac tgtatcaacc aaataattct taggatactt aaaatcgtac aaatcaatag
     9361 ggtgatatac ataaaacgat agaacttcga acgattatcc aatttatccc tcctcacaaa
     9421 tactgattat aaataacatt ttatcgaaaa tcaatatatt attgttaaaa aagtaaaatt
     9481 aaagactaat taacataaat atacttggtt tataatggaa ttttatattt aatttatctg
     9541 agtaatacat gcatcttttt ctttaaatct taactattaa acaagattat ggacctaaaa
     9601 aacacaatat tgattaattt aaaacacgca aacgtctata tctaccaaaa tagtttatat
     9661 tttactattt gtctgataac ctattaattg actagtacgc tagattatta attcttggag
     9721 gaaaatgatt atgaaaaact tcgaaatgat ggcaatggca gcaattgagg atgtacaaga
     9781 ttcagaacta gaacaattaa ctggtggaca agttccaaca attactaaag attgccccaa
     9841 tactgttagc agtgtttgtg taactttccc attcatctct gcttgcaaaa attgtgacta
     9901 atagaaataa cttttaattt ccattattag aaacaatttg cccatggtga atatccatgg
     9961 gcaaattgtt tctaaatatt taatttaagg agttaataaa atgcaacaaa tatataattt
    10021 tccttatcaa gaatgggcta gagcattata tttacacgaa cgaaaaggaa tagatactag
    10081 taagttaact attaaaatta atgaaataaa cttgtggaaa caacgtgccg gattctttac
    10141 ttatgaatta tacaagcata gagttaatga ggatttactt accttagacg aatggaaaac
    10201 gttagcatct aatccacaag tgacaccaca tatttcttat atccccaaat ggatgaaaga
    10261 cttagaagag gctattaata atacatattt tatagaatta aattcggatg attttctaaa
    10321 agaatctata tttaaaaagc cgttctttga gtttgctatt ccatttttaa agtatacaaa
    10381 atataaaatt atacaaaaaa ttcaagagaa ctctacacta aatactttgc tttctgaaga
    10441 taaagtattg atccaatcaa tactcagtcc attagcagag cagattttaa agatatctag
    10501 taaaactctt atttatgaat taaacaaaga aaggttgcag ggacatttag taggtcagac
    10561 aagagaagaa cgctatagat tttttattgc tactaaattc aacaacagtg cttctttttc
    10621 tcaacttcta gacgaatacc cagttttagg tcgcttaatt agcgaaaaaa tgaatttttt
    10681 atataactct atttttaatg cgttaaacga ctggatacta gatagagaaa aagttattaa
    10741 agaattctca ggaacttttc aaagtattgc tcggttagac ctaatgggag atgtgcataa
    10801 cgcaggaaag gctgtattaa aattcacatt tacggataat acatctatta tctataaacc
    10861 tagaccttta tctattgatg tacattttca acagctcctt cagtgggtaa ataaaaaagg
    10921 tatctcagac tctttcaaca cattaaaagt tgtagattgt aaagatcatg gttgggttga
    10981 gtatgtagag catagaccat gctctaccat ggatgaagtt aataactttt ataaaagaca
    11041 aggtagatat ttagcgatcc tatacatgct aaatgcaacg gactttcatt atgaaaacat
    11101 tatagcctgt ggggaacatc cttatctgat tgacttagaa tccttatttc atcactcaac
    11161 ttctaagaag gataagatag ctacagctac tcaaaaggct gaagaattac tggataattc
    11221 tgttatcggc actacacttc taccagtgcg aataaataac cctagatttg ctgaggctaa
    11281 tttcagtggg ttaggtaata atgagggcat agtagtaact tctgtaattg agaattctca
    11341 cactgatgag atgtgtatga aaaagaaaac tttattaata aaacctgagg ttacacattt
    11401 acctagttat aagggaatgc ctattagtta cgaacagttt acttcttata taatagaagg
    11461 tttcacagaa gtgtataaga ttttcatgga agaaaaagaa acacttttat cagaagatgg
    11521 tccaatatat aaattcgaaa aagataaaat tcgtattatt ttaagaccta catattatta
    11581 tggaagaatc ctagaatcta gtaagcatcc taaatattta aagaatggaa tagacagggt
    11641 tcaattattt gatctactat ggagagcaac tgcagacatt cctaacttat ataaggtagt
    11701 acattctgaa tgccaagatt tactacaaga ggatgttccc tacttatata ctagtgtaaa
    11761 tagtagaaat attagggatt gtagagagaa atgtattgaa gatttcttta atgaaacccc
    11821 attagaaagg gtcattaata aaattgaaaa tatatgctta acagatttag agcaacagat
    11881 agaatttatc aatgcttcat ttcattccaa tcaactagaa gaaactaacc caatagataa
    11941 attagaaacc ctaatgtcta aagaacaaga taaagaggaa ctatttaaag ttgataaaaa
    12001 tcaccttaac aaatcaatac ttgaagaagc caaacggatt ggcgaggaaa ttgctgacct
    12061 tgcaatttgg agtgatgata aaaatacgat tacatggtta agcatgggag ttacaaggtt
    12121 aggaaatatt gaatactctg tcatgaaatt gggcctatat agtggaatat taggaatggc
    12181 tcttttttac gcttatcttt ataaaattac aaacatccct aaatttaagg acatatcaca
    12241 agcttctgtt aacacggctt taaaggatta tatacatgga aaacaagatg gacaagaaga
    12301 tcactctgct tatctaggat atgctggggc aatatatgtc tttatgcatt tacattcagt
    12361 atttaaacga ccggacttaa tagaagaagc tgacaaactt cttaatagaa ttgaggagct
    12421 aatagatcat gactctcaat ttgacatact gtctggaaat gcaggactaa ttcctatttg
    12481 tttagatttc tatgaaatga ctggtaataa aaaagccttt tatatagcca aaaggtgtgg
    12541 agatgtacta ttaaatcatt cacataacga taaaggaaac atttattggc gatcccaaga
    12601 catgccccta gataaacctc ctttgactgg tttttcacat ggaacagctg ggattgcatg
    12661 ggccctaact aaattatata aaataacgaa tgaagtgaaa tatttagaac atgccatggg
    12721 tgctattaga tacgagaacc tctcctttaa tcctaaatat aataactggg ctaactatag
    12781 taatacccaa agattacagg aggataaagt ttactctgtt agttggtgta atggtgcaac
    12841 gggaataggg cttagtcgta tgaagatagc taaattgatt cctgagaatg ttcaaattca
    12901 aaaggattta tactctgcct tagatagtgt attaaaaaat ggtttaataa aggactctca
    12961 ttgtctatgt catggtcaac taggaagtct agagttcctt tatagaggtg ccgaggctat
    13021 tgaaaataaa gatttactag aagaggtata taaacaccta tttaaattga tgcaacaaac
    13081 taaagattcg cagtggtggg aatgtggttt tgccaataag tatgttacac ctaatctaat
    13141 ggtcggactt gctggagtag ggtatcaatt aatgagattt tatcaaccta atatcccatc
    13201 agtattaacc ttagaaccac ctcaatatat agcgaaagaa gtatctatga atgatgagta
    13261 atcaaattat agaacataag cgttccgtac cttacattcg tcagttagag aaatcagaat
    13321 gtgggcttac ttgtttagct atggtacttt cctattataa ccatgaggtg gaactctttc
    13381 gtttacgaaa tcatatttct ggtgggcgta acggtataag tttactgacc cttaagaaat
    13441 tggctatatc ttttaatctt gacagtcaag gaaagaaagg atcagttgat gtattgcatt
    13501 ccatccctca ccctgttatt tgttactggg acaacagcca ttatgtagta ttagaaaaaa
    13561 tcagtgataa gttctttttc atagtagatc catcgcttgg taagatgaaa ctcacacttg
    13621 aagaatttag aagcaagtat tcagggtact ttcttactat gaaaccgaca gaaaagttca
    13681 taaaaaagaa aaaagaaaaa aatatactat ggtcgtactt aaaacctttt ctatatgaaa
    13741 gaaaaatttt agcaacaatt attttattcg cttttttatt acaactcata tctatatgta
    13801 ttcctatgtt atcaaagtat gtagtggata aagcttctat ctcaaagcaa ttgaatatag
    13861 tacacatagt aggagtagct atgattagtg ccgttatact acaaatcacc tttcgctata
    13921 tacatgggta tatgttgatt attctacaaa ataaattaga taagaaatta atagagcgtt
    13981 ttatttccca tttgttctct ttacctttac gtttcttcca ggtaaggtca aatggggacc
    14041 tggttatgag gtctcataat atagagatct taagagagtt aattgttaac cacctagtct
    14101 caactataat taatgtattt gtacttgctt ttatgtttgt gtatatgctt tctcaatcta
    14161 tctccctttc cttagggcta ttggcgattg ggatattcca agttatgttt actttaataa
    14221 caagaaataa gatgaaaaat ctttcaactc aggaaatcgc atcaacggct gccttaagaa
    14281 gttatcttac agagtcaatt caaggtattt ctttgataaa aaatgtaggt atcgaagagc
    14341 atattatcca taaatggagt aatttatttg ataaaaaatt agaaaatgct tatcaaaaaa
    14401 ataaagttaa tctatcaatt gaaagtgttt tacaaagtat tcagctctta gtacctgccc
    14461 ttatcatttg gataggcact taccaattaa tccaagggca aataagtata ggtacattat
    14521 ttgcctttca atccctatca atttcttttt taacgcctat taattcacta gcttcatcca
    14581 ttacagcctt aacccagatg gaaactattc tagatcttat tatggatgtt gagagaacaa
    14641 aaaaagaaga tacatcaggg aaatcttttg agaatttgaa gggcaacatc acactaaaca
    14701 atgtatcctt ccaattcgat gcacatagtc ctttagcatt aaaaaacatt aatctggaga
    14761 tacctcatgg aaaaaaagta gcgattatag gagaatcagg atcaggtaag agtactttaa
    14821 tttcactcct caacgggtta tttgaaccga cacagggaac tatatattat gataagtata
    14881 atatggcaga tctagataaa aagttattac gtagtcagtt aggcattgta actcaaaacc
    14941 atattctttt taaccaaacc attcgtgaaa atatctcgct aggtaaccct gatttagatt
    15001 attcagatat aattatttct gcacaactag ccgagataca tgatgatatt atgaaaatgc
    15061 ccatgcaata tgaaactatt atttcagaga atggtacaaa cttatctggg ggccaaaagc
    15121 aaaggctatc tattgccagg gcattaatta atcaacctaa aattctgata cttgatgaag
    15181 ctactagtgc ccttgataca gtaactgagg agaaagtaga tgccaatata agtagtatga
    15241 actgtacgcg aattgttgta gctcacagat taagtacaat tattaactca gatatggtag
    15301 tcattttaaa agacggtcag attgtagcaa atggaacaca taaacaatta gaaaaaaacc
    15361 ctgaatattt aaagttcttc aaaaaacaac agagagatga atttgataca gaacaaataa
    15421 aacacttaca gaaagtttca aattaataat tagcatactc tatattgtaa taactcatcc
    15481 ggctttatat aaaaactagg acatagtgcc ttttccattt gcattaatat gtaaaatcct
    15541 tgaccaactt aacttttttt gagaaaagtt gagttggtcc tttttataag gatattcttt
    15601 aatacttaat aacaacattt agtctgaaat accttattca ttttccatcg atttatgagt
    15661 atgagaataa tataaaccat ttttctggac ccaagggcta tgaaatgtaa taacatcttg
    15721 ccatatgata ctgttattct tttgtgctgt ttccaataaa gttttcaatt cttttttctc
    15781 atattcattc aactaattcg agtgccttgt aaataaagaa ggtgtcttgt taggattatt
    15841 catatagtct caataaagag acaacggctt tttatgtgct ttttaatctt tcctcgcatt
    15901 gtcacaatta atatattctc catactccct aagcactttc ttcttagacg taacaaattt
    15961 cgttttaagt ataacccctg tgtgctatac cataatcctt aatctccttt aaactgttca
    16021 tcgtaggtcg tttgcattcg atccctttct ataatttgtg gtcctccact gatatagaga
    16081 gaagagcata agtgtttttt gctatcacac ggggtgatag gctaggcaga gcctagcaaa
    16141 accgtgatat cacgaaaacc tctaaagtgt gaacctgctg ttgacctaaa ctcctctatg
    16201 tgaacctact gtgaacgtaa aaaatcagtg atgtgaacct actgtgaacc tcaaaaaagc
    16261 acatgttgac ctactgttaa catgtgtttt ttcacttcat ggctaaatct tgttgctttt
    16321 cattcaattt ttggagcttt tcttgtaaac ttttttgttc atctttatag agctgaatgc
    16381 ttgcatcact cgattgaatg gcatccttct tcatcgctat ttttgattcc gtatcggctt
    16441 tttcttcttc cacttggtac ttcatatcac gttgtaattc gttcatttct tgttgcgttt
    16501 gacgcttatg tttgccttct actgtgattg ctttttcata gtttttcatt ttttttaaca
    16561 aactgtttct ctaaatcatt gaccaaaagc gcatattctt gtttgctttt gattcctttt
    16621 ccttcttcac ttttcgtttt tcattggtca gaatagatcg tggtaattaa cgcttgagca
    16681 tctattccct ctgttgaatc tggttctgaa tcactggtta cgtcatccac gtttaccgtt
    16741 tctttttctt cattttcttg atacggatca aaggcaagtg cgtcccaatt tgaagacaaa
    16801 tcgctgattc ttacgacata atagccatca tcttcatata ataaatgaaa gagataaatg
    16861 aaacggtttc gaatcaaata cgtcactaaa tgtcgtttga ataagctgcc tcagtgtatt
    16921 aaataaaaaa tttaaagtta gaaaaatgat tataaaaaaa caagcactta aaggaataag
    16981 tacttgtttt tcagcaacca tatatttcat tgatttatga ggttgcatgc tgtacctcct
    17041 cctgtttctg ttcagataca ggaatgatat aaaaagaact ttgagaaaaa gaaaagtgcg
    17101 ttcgatcatg tgcatcgtat cggtcttgaa ggtattgaaa agctatttga aagtcccaat
    17161 tcatctcttt catgttctct tcgggcacga tataagattg attttgagtg aagtcctctc
    17221 tctcttgatg agtaagtgct gatgaatcaa gaggccgcat tgcaggcttt atacatattc
    17281 taaactgata ctcttgtttg aggaaatcat cactaatcgt aatagatttt gcatttttaa
    17341 aaataataac catgtgattt tttaagagga ttatactatt tacactgttc gcaatccgtt
    17401 gagcatgaag aggtgttgta cggaatttcc ctaactctac ttcaacaaaa atatcctcgt
    17461 gtctatattc cacaccaaca acaaaagaat gtctctgatt tttcgcttgt ctttgattgt
    17521 acatagcaat catccttcct ctgaaaccat tttaatagca agaactatcc tcttttatag
    17581 attcccaagt acctcttctt gtttcttttg ttgttcaatc aacgatttaa tcttgttatc
    17641 acctttttga tcttttttgt tatatcaaga tccttttttt ctttttcata agcagctgtt
    17701 ttttgattga aactttcatt ctgaatatgt gctgctacat atggacattc actttatctc
    17761 ttcacgtacg aaaaagaaat aggtacccgt ttctggctcg aagggcaaac cctatattgg
    17821 catgcatagc tttcactaag ctcaataatg cgtaacgttt tcggcatgta cgaagaacct
    17881 cgtgtatcta ctatttagag tgttatcgct tcgtcggaat tatcctcacg ccatcgtact
    17941 tcacagattg tagatacacc gtcactgttt tattactaga ttaccgatga attttaggat
    18001 ataatcatca aacctttttt taaccgtata ccttaatccc cttgtgatcc atttagagga
    18061 gtttaatatt taaaacctga aataagaaat taccttatac aacttactaa ctcgatatca
    18121 aataacaacg atttataatt atagtacaat ctcttacatg acctgggtag tgcgtttttt
    18181 tatagtactt ttttaaaaag gcactaaagt ttatagtctt ttttgcttga agactataaa
    18241 ctttagtact taaataaaaa aaatgaccat acatatggtc atttttctaa tccacccgac
    18301 ttagcttttt caatagcatc ttttatattc ctaactgaca atttcttgaa aatgctttga
    18361 atttgatttt ttatagtatt tttagacttt gataattctt cttgcatact ctgtcgagag
    18421 tatcctttct ccaacatatt aaatacaacc cgttcgctct gagttaaatt ggtcaattgt
    18481 tgctcatatt ttaaatcgcg ataatcttct aacatagctt caatggctgt gaagttccca
    18541 acataagtgg accttataat attagctatg ttatgcatat ctttttttaa aatataattt
    18601 acagctcctg ctgcaaaagc cttaattatg acatcctttt cacttaaaca agttaacatg
    18661 ataactttcc acttgctatt atctatagat tgcatttttt ttaattcata cgcagcatga
    18721 attccatcca gcttagcacc tgttaagtta atatccacaa gaaaaatatc tactttatca
    18781 atatctctag ctaaccttaa ggtatcttct tccgtcgagc cataacctac taactcgata
    18841 tccttttcag ctttaataat agtctgaatg ctgtgcaacc attctagatc atcttcaatt
    18901 aacactactt ttatcggctt actcaaatca ctcatcctct atctcttagt tgagaaagtc
    18961 agtttgatat ctgtacctac attaacttga ctagaaatct ctagattccc atcacttttt
    19021 accatcacat cataacaata ataaagtccc catccagtat ttccgtcttt taattttttc
    19081 gtggtaaaga atggactctt aacgtattct aaattttctt ttgttattcc aattccatta
    19141 tcagatatga taactacagc tttttttcct tttttattta ttctaacgtt tataatgcct
    19201 tctttttcta ttgcttcaat ggcattctta aacatattca aaaatacctc tttagttggg
    19261 gttttatcaa aaaaagcata tacatcttcg tctaagtatt ctttagttat gactatatga
    19321 ttttcaacaa actccacttc taattcactt ataacgccat ctactacttc agtaagatta
    19381 ttacgctttt ttacaattgt aatgtcttgt gtcttactgt ttatcttttc aaccattttc
    19441 agtaaatgat cagatccact atcgaccatg ttaatccctt cagctgacaa atgatttaac
    19501 tctgatgtat tttctttaat caacttcatg cctgtcacaa ttctaaatat ttggttttta
    19561 atagcgtgat tcataaggct aacacctgtt agaatagctt tatttgcttt aatttgtgtc
    19621 tgcttttcat atttaatctt tatgccgttc attgatccaa caccatcttg cttaaaggct
    19681 ctccatataa aatagctgaa agagatgagc ataaatacaa ttacgtacct ccagtattcg
    19741 tgatggttat caaatacacg tacaatataa tttaatataa gggctgacaa cataattgga
    19801 tgcataatgg taaaagttat aaaacgtgtt tttttcttgt atggatctga ttccgtaaaa
    19861 taggaataaa ggtgtattat gtaaccagtt ataatataag gaactcccca ataaaacagt
    19921 cctttaaaat cagggacgat gtcaggtaca taagtggttg taaatatcat gacgataata
    19981 ggagtaaaca aaatatactt taagttgtta atagttttat tagagaatcg ctctgaatag
    20041 actattgcat gcataagaac tccccaaggg caaaagtaaa tagagaaaaa acctgtaata
    20101 attcttgcat aataaaggaa agtgttaagc caattaaagt tcatatgatg catattcaaa
    20161 atagggataa atgactctat gatagcccta gaaaggcctg cagatgatgc acatgccaat
    20221 agcagtgtca tccaccttaa cggaggatat ttaggatcat aacaataaca tattaaagca
    20281 aataatccac tgataacaaa tagagcaacc attaagttac cccatctatt acattcaaaa
    20341 tttgattagg acatttcact aagtagtctg gtctacctgt tataagaagt tcttctaagt
    20401 catatcccca tgtaacggat acaattttta tgttactttt ttttgaagca ataatatccc
    20461 tatgctcatc acctataaga atagtctcat cccttcttaa gttatgagat ttaatatagc
    20521 tattaattgt taaatttctt ccaaaaaacc ttttagatct aataatttcg tcgaaatact
    20581 ccatatcatt taatttcaaa aacttctcaa tattttcttt tgaattagct gaaattagta
    20641 caagcttaaa ttctcgattt tttaattctc ttaaaacttc tttcatttca ctattaactt
    20701 gtaaatatgg aactgatttc ttatattctt taacaacatc cataactaag ctaggaactt
    20761 taaagaaaga tacattatac tctttaaaac gttggcgaaa agttattgat ctaatgtaat
    20821 ccattttctc ttgaggcatt ttttcataac tatacttgtc tgaaaagctg ttaaaaaggt
    20881 cgtatactaa ctgggctgaa ttaactatcg ttccatcaaa atcgcaaata actgtcttta
    20941 tcacgtttcc acatccattt tcattaaaca atcagaataa aaggcgaaca tttattcatg
    21001 ttatctaatc gtaacaaact ataaacttct ttaaaatagc acatttttcc ttattttgta
    21061 attaaaccct ttataaacaa acatccctta gcactatata atctactttt tttaactata
    21121 tatgtaaaat atttcttatg gtatttccca tcatatacaa ataaggacta ttgactctta
    21181 ttcaagatcc taaataatct aattaacaat tactaaatat ggagggaaag ttgagaaata
    21241 ctcctgctaa taattctaaa aatatatagt gttttcaaac aaagtgacta cttcacaatt
    21301 cttaatatct cctattactg tatccccgcc tttatctgca ctaagttttg tagtctttat
    21361 taaaaaatag actatgaaac ttagtacttt tacaaagaag agactataaa agttcacact
    21421 acccaacgaa cctgtttagc gctatgctaa taatatgtat taccaccctc agtgaaaaaa
    21481 aatacacctt gaaaaggtga tttcttcacc aagctagagg tgacatctaa taaatatact
    21541 cgttttgata tattttgcta atttttattg aattatgaga ctagttaacg ctataataaa
    21601 actaacaaaa acgtgcggat agaaaaaaga cttcaactgt ttaagtagtg cgtcaacact
    21661 cttaaaccgt tccccctaaa tacggtaggg aaaacacttg tcgaagtctc ttgttaatag
    21721 agttagtttt gtacaaaata aaacttatgg ttttatttta tacgaaattg acatctattt
    21781 caagggctta gtttatctta atcaaggcat tgttttcctt ttataaggga gataatgtct
    21841 tttttgtgtt ccttaaagga gaagatgaac aaatgacaaa gatattgact tgctatttac
    21901 ccgatgtaaa taccttcaac ggacgattta aatggttatg gaaagaaaag cctacccttc
    21961 gtaaaaagaa agaggcgttt ttagaaaccc ttcgtacata ctttaaacaa caacaagaag
    22021 ccctacataa agtattccct aaaaaacgga tggaaatgtt agattacgtg atttataacc
    22081 ttgttgctac aggcattcaa gcgatccaat ccaaaacact tatgcaaaaa tttgatgtat
    22141 ctcaaagtac cgtttctcgt tttgtgaaat cgttaaagga aacacctttt atgcttgtgg
    22201 cacgttatat caaagaagat gcaacaggtg ctcatcctga tagctatgtg tttatcctta
    22261 aaagccataa gaattttgat caaatttgtg aggaaatctt ttttgcacat gatacaacag
    22321 gtattcaaac acttcaacaa gaagaaatga caactcctgt gacaactcct gtgacaactc
    22381 ctgaatgtgc tgaaaacgtt gatacaacaa gctttgaggg cgaaaaaacg tcgtccccct
    22441 ttattaacct tgatttacct aaaaatcatt taaataatca tttaatatct gcttcacagt
    22501 catttgctta tatcaaaggt gttcctaaaa aagtaaatca tgtgtacgca gggaaatatg
    22561 gtcatcaact aaaagacttt tatgctcgta ttcgaaatgc tgcaaaagcc gtaaaacgag
    22621 atacaaagat tgagattgtg aaagaacaag tacatgaagt cgcttataca gcgattgtag
    22681 gcttagataa atatgtccat gaggcgaatc ataagggtac tcccctttca ctggatgaca
    22741 tgtgccgtct agtttatcaa attgctcaca atcaatttac gaatctactt aaagggaata
    22801 cagaagaacc atcatctaag tcagacatac atactgaagc tgaaacagcc ctatatacgc
    22861 ctaaacagat catccgcaag gaattggtcc ctgcttggtt acaagctgaa caggagcaaa
    22921 aagagtgtac acaagaacca gctctttctc tagatgagca gcttgaaatg attcaattaa
    22981 agcaagattt agggcaagaa ctaacaccag aagaagaaac tttgctgcag gaacagagta
    23041 ctacgtacag ttcgttagaa atggcgcagc tgaaacaaga tcttggacaa gccttaacac
    23101 cagaggaaca agcgttatta cacgaacatg cccaattaca ggacaccgtt tcgtaatcaa
    23161 aaagtgaaga aatcccttag aagatgatgt ttagtaagag tattatttag aacatacttc
    23221 caaataatca atatataaat ctatgtagga ggagatcacg a
//
