LOCUS       NZ_JADNBL010000011     23102 bp    DNA     linear   CON 12-JAN-2024
DEFINITION  Bifidobacterium longum strain D59t2_181005_F6
            NODE_11_length_87781_cov_28.183, whole genome shotgun sequence.
ACCESSION   NZ_JADNBL010000011
VERSION     NZ_JADNBL010000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bifidobacterium longum
  ORGANISM  Bifidobacterium longum
            Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
            Bifidobacteriaceae; Bifidobacterium.
REFERENCE   1  (bases 1 to 87781)
  AUTHORS   Aggarwala,V. and Faith,J.
  TITLE     Quantification of discrete gut bacterial strains following fecal
            transplantation for recurrent Clostridioides difficile infection
            demonstrates long-term stable engraftment in non-relapsing
            recipients
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 87781)
  AUTHORS   Aggarwala,V. and Faith,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-SEP-2020) Genetics and Genomic Sciences, Icahn School
            of Medicine at Mount Sinai, 1470 Madison Ave, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 29.17x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/12/2024 03:10:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,967
            CDSs (total)                      :: 1,906
            Genes (coding)                    :: 1,845
            CDSs (with protein)               :: 1,845
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 19 of 61
            Pseudo Genes (incomplete)         :: 48 of 61
            Pseudo Genes (internal stop)      :: 3 of 61
            Pseudo Genes (multiple problems)  :: 9 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:10:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 60863
            Orig. end                         :: 83965
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADNBL010000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23102
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23102
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23102
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:13102](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13102)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     CDS             246..467
                     /gene="allorf_61109_61330"
                     /locus_tag="allorf_61109_61330"
                     /protein_id="allorf_61109_61330"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAFLPKSAVDLEFGTFGRATKKPCAQAEQYNLAKRPSPALDGLIS
                     LNLRWLGEPNFGNALARTSTNGLWFTDD"
     CDS_motif       246..287
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAFLPKSAVDLEFG"
                     /locus_tag="allorf_61109_61330_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       288..467
                     /prepeptide="core"
                     /locus_tag="allorf_61109_61330_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.90"
                     /molecular_weight="6350.1"
                     /monoisotopic_mass="6346.3"
                     /core_sequence="TFGRATKKPCAQAEQYNLAKRPSPALDGLISLNLRWLGEPNFG
                     NALARTSTNGLWFTDD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAFLPKSAVDLEFG"
                     /leader_location="[245:287](+)"
                     /alternative_weights="6368.1"
                     /alternative_weights="6386.1"
                     /alternative_weights="6404.1"
                     /alternative_weights="6422.1"
                     /alternative_weights="6440.2"
                     /alternative_weights="6458.2"
                     /alternative_weights="6476.2"
     misc_feature    complement(482..492)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(516..1346)
                     /locus_tag="I2A13_RS07610"
     CDS             complement(516..1346)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013141330.1"
                     /locus_tag="I2A13_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_007053000.1"
                     /transl_table=11
                     /translation="MKPAVEVSITSWKKNVVKPGQEYGRVLLMPGTGYNCDRPLLYWSA
                     QALVEAGWRIDRMNVRNASDDLSTVIPVLNQAIDGWVAAARESGAGKAGDSGDGVAADD
                     SATVLADGAAGSPNRDSDTPSGPRLLLIGKSLTTMTYPHVASHYGLPFVLLTPVLHHAD
                     FDPSARVIPVPAVGDDIVAESEAPSVAEARAIIRAEQAGQSHAASSRYSGPAPLICAGT
                     ADPFYDQARANALTPHVHEYPDANHSIEVPGHWRRSLDYLKEVTASVAQYAATL"
     CDS             complement(1511..1585)
                     /gene="allorf_62374_62448"
                     /locus_tag="allorf_62374_62448"
                     /protein_id="allorf_62374_62448"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGLCGAAHRVHNAAAGPGENCDSP"
     CDS_motif       complement(1538..1585)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGLCGAAHRVHNAAAG"
                     /locus_tag="allorf_62374_62448_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1511..1537)
                     /prepeptide="core"
                     /locus_tag="allorf_62374_62448_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="799.8"
                     /monoisotopic_mass="799.3"
                     /core_sequence="PGENCDSP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGLCGAAHRVHNAAAG"
                     /leader_location="[1537:1585](-)"
     gene            1601..2995
                     /locus_tag="I2A13_RS07615"
     CDS             1601..2995
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013141331.1"
                     /locus_tag="I2A13_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NCS2 family permease"
                     /protein_id="WP_007052999.1"
                     /transl_table=11
                     /translation="MEKFFHLKENGTTVSTEILAGLTTFFAMAYIIVVNPQILSQTGMP
                     WGGVFLATIIAAIIGTLVMGLFANVPYAQAAGMGLNAFFTYTVCFGLGFSWQQTMCMVF
                     LCGLINILITVTKIRKMIILAIPESLQHAIGGGIGLFVAYVGMLNVGLIKFTPGDPKAA
                     AKGGAVAATPGLANFNDKVLWVFLIGLVLAIVFTVMKVKGGMLLAIAITTVIGIPFGVT
                     TWSNSQSISETFSQLPQTFGAIFSAEGFPALFSDPTKLPLVIVTIFAFSMSDTFDTLGT
                     FIGTGRRTGIFSAEDEKALENGHGFSSKMDKALFADSIATSIGAICGTSNTTTYVESSA
                     GIAAGGRTGLTSVVVAICFALSAFLAPVVSAVPSAATAGVLVIVGCMMAASLKEVKWDD
                     IAEAIPAFFAAVFMAFSYSISYGIAGGFIMYCIVKTCKGKAKEVHPIIWTVAALFILDF
                     VCMAIL"
     CDS             3143..3271
                     /gene="allorf_64006_64134"
                     /locus_tag="allorf_64006_64134"
                     /protein_id="allorf_64006_64134"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGIVVNRQLNVHGSSTSALFNIEICSAKKPKNQKASIPNETV"
     CDS_motif       3143..3184
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGIVVNRQLNVHGS"
                     /locus_tag="allorf_64006_64134_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3185..3271
                     /prepeptide="core"
                     /locus_tag="allorf_64006_64134_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.10"
                     /molecular_weight="2911.3"
                     /monoisotopic_mass="2909.6"
                     /core_sequence="STSALFNIEICSAKKPKNQKASIPNETV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGIVVNRQLNVHGS"
                     /leader_location="[3142:3184](+)"
                     /alternative_weights="2929.3"
                     /alternative_weights="2947.3"
                     /alternative_weights="2965.4"
                     /alternative_weights="2983.4"
                     /alternative_weights="3001.4"
     CDS             3177..3293
                     /gene="allorf_64040_64156"
                     /locus_tag="allorf_64040_64156"
                     /protein_id="allorf_64040_64156"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAAARVPYSTSKYVARRSRKTKRLLYRMKRYRSLLVCD"
     CDS_motif       3177..3203
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAAARVPYS"
                     /locus_tag="allorf_64040_64156_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3204..3293
                     /prepeptide="core"
                     /locus_tag="allorf_64040_64156_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="3558.3"
                     /monoisotopic_mass="3556.1"
                     /core_sequence="TSKYVARRSRKTKRLLYRMKRYRSLLVCD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAAARVPYS"
                     /leader_location="[3176:3203](+)"
                     /alternative_weights="3576.3"
                     /alternative_weights="3594.3"
                     /alternative_weights="3612.3"
                     /alternative_weights="3630.3"
     gene            complement(3421..6162)
                     /locus_tag="I2A13_RS07620"
     CDS             complement(3421..6162)
                     /EC_number="2.7.7.8"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /GO_process="GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003807809.1"
                     /locus_tag="I2A13_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="WP_008783408.1"
                     /transl_table=11
                     /translation="MEGPEIKAVEAVIDNGSFGKRTLRFETGRLAQQADGAVAAYLDDD
                     SMILSTTTAGSSPKENYDFFPLTVDVEEKMYAAGKIPGSFFRREGRPSSEAILACRIID
                     RPLRPLFPHTLRNEVQVVETVLAVNPDDAYDVIALNAASASTMISGLPFEGPVSGVRLA
                     LIDGQWVAFPRWSERERAVFEIVVAGRVIENGDVAIAMIEAGAGKNAWHLIYDEGQTKP
                     DEEVVAGGLEAAKPFIKVICEAQDELKKIAAKETKEFQLFPEYTDELYARIDEIAHKDL
                     DEALSIAEKLPRQDRIHEIKEHVREVLADEFTDMDDAEKDKELGNAFKELQRQIVRRRI
                     LTEDYRIDGRGLRDIRTLSAEVDIVPRVHGSALFQRGETQILGVTTLNMLKMEQQIDAL
                     SGPQSKRYMHNYEMPPYSTGETGRVGSPKRREIGHGALAEKALVPVLPSREEFPYAIRQ
                     VSEAIGSNGSTSMGSVCASTLSLLAAGVPLKAPVAGIAMGLVSGDVDGKHIFKTLTDIL
                     GAEDAFGDMDFKVAGTSEFITALQLDTKLDGIPADILAAALQQAKEARATILEVINECI
                     DGPAEMSEFAPRIITTTVPVEKIGEVIGPKGKMINQIQEDTGAEIAIEDDGTVFISSEG
                     GDAAKKAKSIIDSIANPHVPEAGETYNGKVVKTTSFGAFVNLTPGTDGLLHISQIRNLA
                     NGERIDAVEDVLKEGDTVEVIVQGVDDRGKISLAIPGFEDQENNARPSRGDRDDRRGGR
                     GRGDRDDRRGSRGRRSDRDDRDFDDRDDRPRRRRSDDFEDDYDDRPRRRRSDDRDFDRD
                     DRDDDRPRRRRSADRDFDDRDDRDARDSRDDDRPRRRRSSDRDDRGDRDDRRGGSRGRG
                     RGSDRNPRYATDDNYDDYRADREERTERPRRRVRRDFDPFED"
     misc_feature    complement(6180..6194)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.6"
                     /tool="antismash"
     gene            complement(6438..6707)
                     /gene="rpsO"
                     /locus_tag="I2A13_RS07625"
     CDS             complement(6438..6707)
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011559497.1"
                     /locus_tag="I2A13_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S15"
                     /protein_id="WP_007053775.1"
                     /transl_table=11
                     /translation="MALTADEKTQIINEYATHEGDTGSPEVQVALLSKRIADLTEHLKE
                     HKHDHHSRRGMQLMIGDRRRLLDYLKRVDINRYRSLIERLGLRR"
     gene            complement(6898..9135)
                     /locus_tag="I2A13_RS07630"
     CDS             complement(6898..9135)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008783409.1"
                     /locus_tag="I2A13_RS07630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_195242605.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.5e-29, bitscore:
                     94.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSWRRHRVPFIEQGEHSECGLAAAAMILAAFGHPVTMDELRRRY
                     GAPRGGLSLANIVTVLSDSGIRVRAVTTPSAEALKTVMTPCILHWDDNHFVVLDHYAYG
                     RFRIADPANGRHAYTPGELAAHCSGAVLIPQPTNDGCATIPIRPRSGTVSILTGFLRRN
                     MPAIGLSLLFSLVVQGLTLIVPAGTGYMVDHGSLAAQSGFPPLVATMLLASLLVYYAVG
                     ALNTVMLTRVQVRFGRYLSRRYMTGVLDREFPFFVNRSGGDLIYRANLVMVVEQIVTGS
                     LPSTVVSMVFLVVYLIMMIAYSVPLTMLTLTVCAAVLVVSVIYSLRNRTLVERATVAQA
                     DVQRAFIETFSGIETVKSLNLESHCYDRWSARLGAQLDYQTRQGRLSALLSSLSSALVF
                     VLPLCVVAFGMTFVGRGTLALGAVVGFMSLASAFVTPFSGIVGVISQIMAFATYMCKIC
                     EMIPAGEGGGASLECDEPGGEPGDVGLGDGGRSACGGPSGDESGDGILERLHATGVGYS
                     YTAFDAPVLSDVDCDIRKGDKIAIVGPTGSGKSTLLKLLAGLIEPVCGTVTINGGGCRI
                     YDADSRWKAGRLAYVHQESTVFNETLRDNITLHRPWLTDDDIVRACEVAGINEGMMDPV
                     VGLDAMVSERGMNLSGGQRQKVAIARAVVGRPDFLLMDEPTSALDNDTERHVMTALLDS
                     DNACIVVAHRLASIRDFDRIHVMDHGQIVESGTHDELLQAGGLYSRLYRQE"
     gene            complement(9132..9950)
                     /locus_tag="I2A13_RS07635"
     CDS             complement(9132..9950)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013141334.1"
                     /locus_tag="I2A13_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_010081693.1"
                     /transl_table=11
                     /translation="MTADHINHADRTDNGEHAIIAVEHVTFGYKKKQTVLEDIDFTVPQ
                     GQSLAILGYNGVGKTTLFRLIVGLLRPREGRCVIDRRRVPSMRDVFQMTENGNLVGTMT
                     VRDNIHFRQLLFRSGKGIADGGHTVDSKRLEDEPLVRAFELEGHLDKKVAELSTGLRKR
                     VGIVAGMLFDPHVIMLDEPSNAIDPITRSLLVDYVNQLRADERTLLTVTHDLEYCWNVA
                     DRIIILDDKHLVKDMMLAEFDDYEAFTKASTLGRDRTHVDFGLPARGRQA"
     gene            complement(10001..13102)
                     /locus_tag="I2A13_RS07640"
     CDS             complement(10001..13102)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012472138.1"
                     /locus_tag="I2A13_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_022527864.1"
                     /sec_met_domain="DUF4135 (E-value: 1.5e-90, bitscore:
                     296.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4e-35, bitscore:
                     113.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATAMPDALRQYRASHAEDMLSATVEWKNRRNPLRDEDYQGIAD
                     ALGDDASVVETVIADRERKLSGHVEPAWSVELQTILNRYDSEEERVERTGYATAFAPFV
                     AYVKAELQAYMSACSLPMNDERLIEQCLSAYVERLLGIGLKTVVWELHVARQAGSLGDG
                     DAKRQLRRYFELLATDEYRGHMYAKYPVLLRFVTQTTVHYIDFVKEMLDRVSMDRDELA
                     SFAGVGDDFRLEDMSIDRGDAHDGGRAVAMLTIGGRKIVYKPRDLHIHELFAGLVRRCE
                     RTKGFLPMRVSDVLTKSGYAYEEFVEHGTCEDARQVERYYTRYGQLLGLVWLLHGDDMH
                     HENIIASGEYPMVVDFETIATNHVTMDMPDGTDADIRVSTILRDSLASSCLLPAKTAMS
                     ADGTSVDISAFETGEQTMPGIVASPVGLDSADAHYERNAVTFSKDGCAVTLDDAVVDPY
                     HYKRQILQGFRNTVAAAMTIDADEWDAMLSGEDTTVRVLVRNTSAYARFADFIHHPSAL
                     KDMLDVEAILENLYVYPFRDKRIFASEYRQMLAGDIPMFTAQLTGHDLHAPDGTTIDGV
                     CERSVRERVLDTIGHLDEQAALQSRIIRNALRMEPGMEDAHPTASVSSDTDAEHYPIEL
                     GTRIADTAILQETDGTVSWLTANRSDTMAADKTVDERYEPGAPTSGLYDGMAGTGMFAA
                     ELYRRTHDERWRDLCTRMMRSLMRRKDRGITYSGFTSGLSRSYCALRMANAGITSPEAR
                     RCMTQTVRMLPAYIDDMLPKLLQRDNPQPSFHLDYLTGAGSSIMLYLRLYDVFHDMRIV
                     EQTSRLGRTVIRAFPETQRNADESDDMPYPTGAAHGLEGMAVAFWKLYAATGNREFAEF
                     ARMLWRKSDARRSGAKQEDAGKWCRGKVGVLWARNELAATAGADGERFFEDENGRAFPD
                     KADITALLGNADWDDDGVCHGRCGMIDTLISIGNANGDEWYRMQAQRLMDDMIAQARSS
                     GRFRLRQSREFVDLSYFQGPVGVAYTMLRLNDPSTPSILALETR"
     misc_feature    13083..13096
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     gene            complement(13174..13911)
                     /locus_tag="I2A13_RS07645"
     CDS             complement(13174..13911)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010081695.1"
                     /locus_tag="I2A13_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin family protein"
                     /protein_id="WP_008783412.1"
                     /transl_table=11
                     /translation="MTSMVAYVASRNPQSQTLRSVRLIQDAVSANIDAEWTILTPNDTT
                     ILPSDGTASEFSTGVDHIELNGLDDSARVKKAIERCDYLILGSPTYGHNVSGDMKILMD
                     RLTYWGHLFHLAGKPGMAMVSATTNGFLEVGELMERFMESLGIIIDETAYHTTFTPFDE
                     AMADQTAAAIVRALNTLRDGVVPETSERQELAFQSYKRDYARRDGSDAESRYWRERGMF
                     DCATFHEYVETRRKLPESVHAER"
     gene            complement(13951..14610)
                     /locus_tag="I2A13_RS07650"
     CDS             complement(13951..14610)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012472137.1"
                     /locus_tag="I2A13_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_008783413.1"
                     /transl_table=11
                     /translation="MKAILFRDCKACFQSFKNWGMVLIIMVTAIFVEMVASGAGILDPF
                     TWAVFFGPFFIYSSCSVMVSILYQDFRDGLFELYIQSGRSYWSYCWCKCLFPVILTVIS
                     VLLNLAFMRVLSSGFQITAGADDAIGALIVSVLGTIVCSLGAMPMVYVSRNSDPTMAQL
                     VLVLIAVLLQLAYMLVIVNVMPLCLFSVGYVVLVVVAIGISTGVFSRYFINTNIEL"
     gene            complement(14694..14894)
                     /locus_tag="I2A13_RS07655"
     CDS             complement(14694..14894)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0005488 - binding [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010081696.1"
                     /locus_tag="I2A13_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lichenicidin A2 family type 2 lantibiotic"
                     /protein_id="WP_008783414.1"
                     /transl_table=11
                     /translation="MSINEKSIVGESFEDLSAADMAMLTGRNDDGVAPASLSFAVSVLS
                     VSFSACSATVVTRLASCGNCK"
     CDS_motif       complement(14790..14894)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSINEKSIVGESFEDLSAADMAMLTGRNDDGVAPA"
                     /locus_tag="I2A13_RS07655_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14694..14789)
                     /prepeptide="core"
                     /locus_tag="I2A13_RS07655_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="2915.4"
                     /monoisotopic_mass="2913.5"
                     /core_sequence="SLSFAVSVLSVSFSACSATVVTRLASCGNCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSINEKSIVGESFEDLSAADMAMLTGRNDDGVAPA"
                     /leader_location="[14789:14894](-)"
                     /alternative_weights="2933.4"
                     /alternative_weights="2951.4"
                     /alternative_weights="2969.4"
                     /alternative_weights="2987.4"
                     /alternative_weights="3005.5"
                     /alternative_weights="3023.5"
                     /alternative_weights="3041.5"
     gene            complement(15204..16364)
                     /locus_tag="I2A13_RS07660"
     CDS             complement(15204..16364)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012472136.1"
                     /locus_tag="I2A13_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_008783415.1"
                     /transl_table=11
                     /translation="MVRRLAMKTILVVRKKCLGVSKKNLVLSIVAMTCLAACIAEWILD
                     SPESLNDGFIRIVYMLAVSMLPLYPVPATWGIIVIAFLNELMPCLSQCDESWGVLVSLA
                     IQGYAAVWWNGVTATVLLSISALLNYAIYRENSEFGSFDGSINLVVLLWFVFLLGVWLR
                     QRNGLEKKKELEKKAEIVRYNLQLAEGMHDAMSGELTRMLVIVQEGIDASKEEELKRWR
                     KLQNGINRIFQDLHSVMNYLSDDDHKQDDVFHVSLAEHIQATLSESDRRLHDKGFCGHS
                     SLRGVSSAMLNSWNQIIVNLLREIYTNIERYADKSEYSVIVTFSNNAVDIVQVNKCRQK
                     SRRCVTLGARKGLSIYSRLISGQGGFIRYEKDGEEWSFYCMLPLLT"
     gene            complement(16358..17029)
                     /locus_tag="I2A13_RS07665"
     CDS             complement(16358..17029)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012472135.1"
                     /locus_tag="I2A13_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_022527867.1"
                     /transl_table=11
                     /translation="MGNPNEIRLAIVDNDDFVLMGLAAFLSRHLPNVRLAWKANTGTDA
                     LEYATDPANEADILLVDMSLEDMPGDMVCREIRSRNRMLPLLAVTSFSLTRYARRAAEG
                     GAQGIVSKADFPALCKAVKLVSDGHTLCVRVGGETIGFEDVDAAYHRLVRLPVNRIERL
                     SEREKYAMELYSQSYKPTQIARMMDVSAGTVKTYLDRVQNKLHLTSRAELIAYWWRRER
                     W"
     gene            17147..18220
                     /locus_tag="I2A13_RS07670"
     CDS             17147..18220
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012577699.1"
                     /locus_tag="I2A13_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS30 family transposase"
                     /protein_id="WP_101028048.1"
                     /transl_table=11
                     /translation="MGEVYSHLSEEERRVIRIEIGNGTIICGIVLMLGRNASTVGREIK
                     RDTWFPSNENESYRPYRPKRLKTGPWTGRYYIAGPAQRKAGRRRAEPRRRHRLSCERLW
                     ARVAEWLGRGWSLLPVSGRLRVLFPDDSAMRVCPETVCRWIHADRRRRERWARRLPRGH
                     GRRRRRGGGRTSRFPIPGRVPISERPPEAGDRSGFGHWEADGVIGAGCNLHTEVERKTR
                     FLMAGIVPGKTAGESVGAQLAMFSPLPAGARGGVTHDNGTGFARHTRLRDGLGMDTCFA
                     DPYSSRRRGSNENRNGMIRRYLPKRSEIRMDMAGELREIVDEADNRPMRVLDYRTPAEA
                     FADELLELQDQQGVLHL"
     gene            complement(18301..18987)
                     /locus_tag="I2A13_RS07675"
     CDS             complement(18301..18987)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014485310.1"
                     /locus_tag="I2A13_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="teichoic acid transporter"
                     /protein_id="WP_014485310.1"
                     /transl_table=11
                     /translation="MEQESNEQEPNEATEIVGGKVETVEVSKHPEASIPETDLSLADIE
                     RRRSHPLRWALIILAVLCAIIAPYWFGRSLAVNNTDSIVAVLGGVSPQGIALVGWVTVV
                     IAYVGLAMAVVVSPSWPWLIVFVIGLAGEQFIAGLSMLNLNFWYSTYVVYGKQAGLANA
                     ANLGIMGAAIGIAVYALVFVGLLVIIRKTSPLNVLTKSWASFILYFVIETIALLVVLFG
                     GLLTTV"
     CDS             complement(19038..19271)
                     /gene="allorf_79901_80134"
                     /locus_tag="allorf_79901_80134"
                     /protein_id="allorf_79901_80134"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSWSGRSICLRLCCIAGDGGAGHHLSCFRNANRASGACLRAIMTL
                     LPRIRIRRIVARIMVRAMASNRSYRRLAQHAR"
     CDS_motif       complement(19161..19271)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSWSGRSICLRLCCIAGDGGAGHHLSCFRNANRASGA"
                     /locus_tag="allorf_79901_80134_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19038..19160)
                     /prepeptide="core"
                     /locus_tag="allorf_79901_80134_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="4736.8"
                     /monoisotopic_mass="4733.8"
                     /core_sequence="CLRAIMTLLPRIRIRRIVARIMVRAMASNRSYRRLAQHAR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSWSGRSICLRLCCIAGDGGAGHHLSCFRNANRASGA"
                     /leader_location="[19160:19271](-)"
                     /alternative_weights="4754.8"
                     /alternative_weights="4772.8"
     gene            complement(19296..19751)
                     /locus_tag="I2A13_RS07680"
     CDS             complement(19296..19751)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015438411.1"
                     /locus_tag="I2A13_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_022527870.1"
                     /transl_table=11
                     /translation="MAVNSSVEKQPVDQQASGEVQAEIDTRSDGVSPMPNDVSKHNDVS
                     KHPVASIPESTLSLADIERKRSHPALWLAYALLVIAAIVVPYWWGRAIAVNDTQWLLVL
                     RTSGARRRVPRLRRKPAANPISTYPPNAAPSSSPSPAKSRTTIYVTC"
     CDS             complement(19907..20140)
                     /gene="allorf_80770_81003"
                     /locus_tag="allorf_80770_81003"
                     /protein_id="allorf_80770_81003"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVEHDIGVECAILETKELVCGRLAVFISNRRRSPDIKYGCVSMLP
                     LCGDVSGVSNSDMVRPYEHMYGLCRPPKHGCD"
     CDS_motif       complement(20078..20140)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVEHDIGVECAILETKELVCG"
                     /locus_tag="allorf_80770_81003_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19907..20077)
                     /prepeptide="core"
                     /locus_tag="allorf_80770_81003_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.50"
                     /molecular_weight="6177.1"
                     /monoisotopic_mass="6173.0"
                     /core_sequence="RLAVFISNRRRSPDIKYGCVSMLPLCGDVSGVSNSDMVRPYEH
                     MYGLCRPPKHGCD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVEHDIGVECAILETKELVCG"
                     /leader_location="[20077:20140](-)"
                     /alternative_weights="6195.1"
                     /alternative_weights="6213.2"
     gene            complement(20277..23078)
                     /locus_tag="I2A13_RS07685"
     CDS             complement(20277..23078)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013582930.1"
                     /locus_tag="I2A13_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 43 glycosylhydrolase"
                     /protein_id="WP_195242606.1"
                     /transl_table=11
                     /translation="MPVFADDSTPSSTPSDGSYTTTDSGDGTYSIPMLNTDVPDISVIR
                     VSKDDPNNKDGRDVYYMVSTTMELSPGSPIMKSYDLVNWWIVTYVYDRISMSDASSLRN
                     GASSYGEGEWAPSLRYHNGRFYVLFNTNNLNGAYIYYTDDIENGPWTKIALNRGFHDPS
                     LYFDEQGSPWIISGVNQYRLSDDLTTVVESHENIISAEQFTDDLGETPTGFEGSQTFKI
                     GDYFYTPTIYWGKDGRTVMLLRTTDLLDGSKYEAKKYYLGAFAQGSLVEVDNGDGTTSW
                     HGFFFRDTYPTGRIPGLIPATWGDDGWPVFGDNNQVSASDTYDKLIDLPADLENLVRQR
                     SLVNSDDFDNDAPHQSYQDQDWWTLEEPPQVDDSLIGIELVDNGDFENGTESWTPQWNG
                     TLTAITDGSLSGTTSLAVTNRGEYNGAGPGQSMDGKLQQGVTYRASATIRYDHEMDGVD
                     SSAVTSHLFYVAIQYADGTINRVATGTVKRGETTTITGEFSIPSDANVEGSKLIVETAW
                     GAEGTCMDYVIDDISLIGLADEKEYPVAEEYQPNGSNLDLVWEWGHNPDNRYWSLTDRE
                     GWLRLTNGHKVSATAKYMKGTYGDLTYFETARNVLSQRTFGGSMSVETHMDVSHMKDGD
                     TAGLATYTRSFAYAAVRQENGQRTLGVVKRVYDNGVKDADGNIVDDTIDRDAEEAFVSG
                     GTVTLPDDATNVWIKSDNTLDNASGKLTIQYWYSLDGKQWSKLGDEQGPLTYDWSLSHF
                     KGYRIGLFNYAKENTGGYVDFDYYDLSDVLTSDGKAVDTSKLRSAIDQADSLQSAEYPM
                     DEWDKMLTLLDKAKQALASDPSTQNEVDAPQRALSLQLAQLAVDRQSGDGGNPGGGDQT
                     SDGNQSGNGDQTGDGGQQQSSTADDNSSELSSTGSSVTPMVLSAIALMLAGISVIRIRR
                     SSR"
ORIGIN
        1 tcacgaaggt gatggcggtc gggccggaga gaatctcgtc gagaccctca atgcccgctt
       61 ccttggcggc gatgcgtgcc agcgtgttct ttgccacggt gtaggaagta tcgcggccta
      121 gcttttcacg cagatcggaa atctgcggaa cggtaagccc gcggtactcg gtcaggtaga
      181 cggcgtcagc gttacggaat tcttccgtaa gctgagcgac taccgcttcc ttttcgggcc
      241 tcttcatggc gttccttcct aagtcggccg ttgacttgga gttcggaact ttcggccggg
      301 caacaaaaaa gccctgcgca caggcagagc aatataatct cgcgaagcga ccttcgccgg
      361 cccttgacgg gcttatatct ctcaacctgc gctggcttgg cgaaccaaac ttcggaaatg
      421 cactcgcgcg cacttcaacc aacggtctgt ggtttacgga tgattagatt acggatggtc
      481 agcgacattg cagaattcgg gcgtgtcgcg gggcattaca gcgtggcggc gtactgggct
      541 acggacgcgg tgacttcctt cagatagtcg agcgagcgac gccagtggcc gggcacctcg
      601 atcgaatggt tggcatccgg gtattcgtgc acgtgcgggg tgagcgcgtt ggcgcgggct
      661 tgatcgtaga acgggtcggc ggtgccggcg cagatcagcg gtgccgggcc ggagtatcgg
      721 gagctggcgg cgtgcgactg gccggcctgt tccgcgcgga tgatcgccct tgcttcggcc
      781 acgctcgggg cctcggattc ggcgacgata tcatcgccga cagccggcac cggaatcacc
      841 cgggcggatg gatcgaagtc ggcgtgatgc agcaccgggg tcagcagcac gaacggcaga
      901 ccgtagtgtg aggccacatg tgggtaggtc atcgtcgtca gcgacttgcc gatcagcaac
      961 aggcgagggc cggacggggt gtcggaatca cggttcggcg agccagctgc gccatcggcc
     1021 agcacggtag cagaatcatc ggcggcaacg ccatccccgg aatcaccggc tttacccgcg
     1081 ccggactcgc gcgcggcggc cacccagccg tcaatcgcct gattgaggac cggaatcacc
     1141 gtggacaggt cgtcggaagc gttgcgtacg ttcatgcggt cgattcgcca gccggcctcg
     1201 accagagcct gggccgacca gtagagcagc ggacggtcgc agttgtagcc ggtgccgggc
     1261 atcagcagta cgcggccgta ctcctgaccg ggcttgacga cattcttctt ccaagaggtg
     1321 atgctgactt cgacggccgg tttcatcgcg cgccttcctt ccacgggtgt gtcctgcgtg
     1381 tcccctgagt tgttccgaat tattctggca gtcagtctac tcccggaccc gttcacgttg
     1441 cctccacaag ctataatcgg ccacggttct gattgggtgc gcagcgcctg acgcgcgttg
     1501 ggcaggccga tcagggcgag tcgcaattct cgccggggcc agccgcagca ttatgcacgc
     1561 ggtgcgcagc cccgcataaa cccaaggaag tagagagtaa atggagaagt tcttccattt
     1621 gaaggaaaac ggcacgaccg tctcgactga gattctggcc ggcctgacca cgttcttcgc
     1681 gatggcttac atcatcgtcg tcaacccgca gatcctgtcg cagacgggta tgccgtgggg
     1741 cggcgtgttc ctggccacca tcatcgcggc catcatcggc accctggtca tgggcctgtt
     1801 cgccaacgtg ccgtacgccc aggccgccgg catgggcctc aacgcgttct tcacctacac
     1861 cgtgtgcttc ggcctcggct tcagctggca gcagaccatg tgcatggtgt tcctgtgcgg
     1921 cctgatcaac atcctcatca ccgtcaccaa gatccgcaag atgatcatcc tggccatccc
     1981 ggagtccctg caacacgcca tcggcggcgg catcggcctg ttcgtggcct acgtgggcat
     2041 gctgaacgtc ggcctgatca agttcactcc cggcgatccg aaggccgccg ccaagggcgg
     2101 tgccgttgcg gctaccccgg gtctggccaa ctttaacgac aaggtgctgt gggtcttcct
     2161 gatcggcctc gtactggcca ttgtgttcac cgtgatgaag gttaagggcg gcatgctgct
     2221 ggccatcgcc atcaccaccg taatcggcat cccgttcggc gtgaccacct ggtccaactc
     2281 gcagtccatc agcgagacct tctcccagct gccgcagacc ttcggcgcga tcttctccgc
     2341 cgagggcttc ccggcactgt tctctgatcc gaccaagctg ccgctggtca tcgtgaccat
     2401 cttcgccttc tccatgtccg atacgttcga caccctgggc actttcatcg gcaccggccg
     2461 ccgcaccggc atcttctccg ccgaggatga gaaggctctg gagaacggcc acggcttctc
     2521 ctccaagatg gacaaggccc tgttcgccga ctccatcgcc acctccatcg gcgccatctg
     2581 cggcacctcg aacaccacca cctacgtcga gtcttccgcc ggcatcgccg caggcggccg
     2641 aaccggcctg acctccgtgg ttgtggcgat ctgcttcgcc ttgtccgcgt tcctggcccc
     2701 ggtcgtctcc gccgtgccgt ccgccgcaac cgccggcgtg ctggtgatcg tcggctgcat
     2761 gatggccgct tccctgaagg aagtcaagtg ggacgacatc gccgaagcca ttccggcgtt
     2821 cttcgccgcc gtgttcatgg ccttctccta ctccatctcc tacggcatcg ccggaggctt
     2881 catcatgtac tgcatcgtga agacctgcaa gggcaaggcc aaggaggttc acccgatcat
     2941 ctggactgtg gccgcgctgt tcattctgga cttcgtgtgc atggcgattc tgtaacgctg
     3001 attgacaacg gattagcctt taaggattaa tccgccgcca tacggcataa aggccgggct
     3061 ctcacaaggg cccggccttt gttgttgcca cagtgatcaa cgcccatgag taccttcgat
     3121 gatcatccgc cattcttgat gcatgggaat agttgtcaac cgacaactaa acgtacatgg
     3181 cagcagcacg agtgccctat tcaacatcga aatatgtagc gcgaagaagc cgaaaaacca
     3241 aaaggcttct ataccgaatg aaacggtata gaagcctttt ggtttgcgat taagctcttc
     3301 tcacccgaga gaagctagag aacgatcagt cctcgaatgc cgaaccgtta agcgggaagc
     3361 cctgcgggct tcccgtaggt gagaggagcg gctatgccgc gaccgatccg tgagagggat
     3421 ttagtcctcg aacggatcaa agtcgcgacg gacgcggcga cgcgggcgct cagtacgctc
     3481 ttcgcggtcg gcgcggtagt cgtcgtagtt gtcgtcggtg gcgtagcgcg ggttacggtc
     3541 cgagccacgg ccacggccac gggaaccgcc acggcggtca tcacgatcgc cacggtcatc
     3601 gcgatcggaa gagcgacggc gacgcggacg atcatcgtca cgggagtcgc gagcatcacg
     3661 gtcatcgcga tcgtcgaagt cacggtcggc agaacgacgg cgacgcggac gatcatcatc
     3721 gcgatcatcg cgatcgaagt cacggtcatc ggagcgacgg cgacgcggac ggtcgtcgta
     3781 atcatcctcg aagtcatcgg agcgacggcg acgcggacgg tcgtcacgat cgtcgaagtc
     3841 acggtcatcg cgatcggagc gacggccacg gctgccacgg cgatcgtcac ggtcaccacg
     3901 gccacggccg ccacggcggt catcgcgatc gccacggctc gggcgggcgt tgttctcctg
     3961 atcctcgaaa ccagggatgg ccagggagat cttgccgcga tcatcgacac cctgaacgat
     4021 cacctcaacg gtgtcgcctt ccttgagcac gtcttcgacg gcgtcaatac gctcgccgtt
     4081 ggccaggttg cggatctggg agatgtgcag caggccgtca gtgccggggg tgaggttcac
     4141 gaaagcgccg aacgacgtgg tcttgacgac cttgccgttg taggtttcgc cggcctcggg
     4201 cacgtgcggg ttggcgatgg aatcgatgat ggacttggcc ttcttagcgg catcgccacc
     4261 ctcggaggag atgaagacgg taccgtcatc ctcgatggca atttcagcgc cggtatcttc
     4321 ctgaatctgg ttgatcatct tgcccttcgg gccgatgacc tcgccgatct tctcgaccgg
     4381 aacggtggtg gtgatgatgc gcggagcgaa ctcgctcatc tcagccgggc cgtcgatgca
     4441 ctcgttgatg acctcgagaa tcgtggcgcg ggcttccttg gcctgctgca aagcggcggc
     4501 caggatgtcg gcggggatgc cgtcgagctt ggtgtcgagc tgcagggcag tgatgaactc
     4561 ggaagtaccg gccaccttga agtccatgtc gccgaaggca tcctcggcac ccaggatatc
     4621 ggtgagggtc ttgaagatgt gcttgccatc aacgtcgccg gacacgaggc ccatggcgat
     4681 gccggcaacc ggggccttca gcggcacgcc ggcagccaaa aggctcagcg tggaggcgca
     4741 cacggaaccc atcgaagtgg aaccgttgga accgatggcc tcggagacct ggcggatggc
     4801 gtaggggaac tcttcacggc tcggcagcac cggcacgaga gccttctcag cgagggcgcc
     4861 gtggccgatc tcacgacgct tcggggagcc gacgcggccg gtctcgccag tggagtacgg
     4921 cggcatctcg tagttgtgca tgtagcgctt ggactgcgga ccggacagcg cgtcgatctg
     4981 ctgctccatc ttgagcatgt tcagggtggt gacgcccaga atctgggtct cgccacgctg
     5041 gaacagggcg gagccgtgca cgcgaggcac aatgtccacc tcggcggaca gggtgcggat
     5101 gtcgcgcagg ccacggccgt cgatgcggta gtcctcggtc aggatgcggc gacgcacaat
     5161 ctggcgctgc agttccttga aggcgttgcc cagctccttg tccttctcgg cgtcgtccat
     5221 atcggtgaac tcgtccgcga gcacctcgcg cacgtgctcc ttgatctcgt ggatgcggtc
     5281 ctggcgcggc agcttctcgg cgatggagag ggcctcgtcc agatccttgt gagcgatctc
     5341 gtcgatgcgg gcgtacagct cgtcggtgta ctccgggaag agctggaatt ccttggtctc
     5401 cttggcggcg atcttcttga gctcgtcctg agcctcgcaa atcaccttga tgaacggctt
     5461 ggcggcctca agaccaccgg ccacgacctc ctcatcgggc ttggtctgac cctcgtcata
     5521 gatgaggtgc caggcgttct tgccggcacc cgcctcgatc atggcgatgg caacatcacc
     5581 gttctcgatc acgcggccag cgaccacaat ctcgaacacg gcgcgctcac gctcgctcca
     5641 acgcgggaag gcaacccact ggccatcaat cagcgccaga cgcacaccgg agaccgggcc
     5701 ttcgaacggc agaccggaaa tcatggtgga agcggaagcg gcgttcaggg cgatgacatc
     5761 gtaagcgtca tcagggttca cggcgagcac ggtctcgacg acctgcactt cgttgcgcag
     5821 ggtgtgcggg aacagcggac gcagcgggcg gtcgatgata cggcaggcga ggatggcctc
     5881 ggagctcggg cggccttcac gacggaagaa cgagcccgga atcttgccgg cagcgtacat
     5941 cttctcttca acatcgacgg tcagcgggaa gaagtcgtag ttctccttcg ggctggaacc
     6001 ggcggtggtg gtggacagaa tcatggaatc gtcgtcgagg taggcggcca cagcgccatc
     6061 ggcctgctgg gcgagacgac ccgtctcaaa gcgcagcgtg cgcttgccaa acgatccatt
     6121 gtcgattacg gcctcaacgg ccttgatttc gggaccctcc atagggttcc tccttcttta
     6181 attttctaat tattcctaca tactgtgctg cggttcgacg actcgcttga accgcaaccg
     6241 tcctcttcag cggacgtcac ataccttgtt tcgactgacc ccttggccgt cgttcctcgt
     6301 gtcaacccct tcattcgggt tctcttgtcg gccttacctg ctggcctatc ctctaaccct
     6361 cttgccgttg ttgccgttgg ctggcgatat gtaaaacgcc cgagcaccat cctaggtact
     6421 cgggcggaag tcttcaatta tcgacgcaga cccagacgct cgatgaggga acggtaacgg
     6481 ttgatgtcaa cgcgcttgag gtagtcaagc aggcgacgac ggtcaccgat catcagctgc
     6541 ataccacgac gggagtggtg gtcatgcttg tgctccttga ggtgctcggt caggtcggcg
     6601 atacgcttgg acagcagagc cacctggacc tcgggggaac cggtgtcacc ttcgtgcgtc
     6661 gcgtactcgt tgataatctg ggtcttctcg tcagccgtca gtgccacggc gtcctcctta
     6721 ttgtgtcgtt gcgcggtgtt tcgtgcaggt tcgctcgaaa cgctctctat ccgcgggcga
     6781 aattacgcca aatggaaact atacggcagg ggccggactg gggcctcatg agccgagggt
     6841 gtaagggata aggtgtaaag ggtaagggtt taaaggcgta agggtgtaag ggaacactca
     6901 ctcctgccgg tacagccgcg aatacaatcc gccggcctgc agcagttcgt catgcgtacc
     6961 ggattcgacg atctgcccat gatccatgac atggatgcgg tcgaaatccc gaatcgatgc
     7021 gagtctgtgc gccacgacga tgcacgcatt gtcggagtcg agcaacgccg tcatgacatg
     7081 tcgctcggta tcgttgtcca gagcactggt gggttcgtcc ataagtagga agtccggtct
     7141 tccgacgacc gcacgcgcga tggcgacctt ctgccgttgg ccgccggaca ggttcatgcc
     7201 gcgttcactg accatggcgt ccaagccgac gaccggatcc atcatcccct cgttgatgcc
     7261 ggcaacctcg cacgccctga cgatgtcgtc atccgtcagc cacggacggt gcagcgtgat
     7321 attgtcgcgc aaggtttcgt tgaacaccgt ggattcctga tgcacatacg ccagcctgcc
     7381 ggccttccat cggctgtccg cgtcgtaaat ccggcatccg ccgccgttga tggtcaccgt
     7441 gccacagacg ggttcgatga gtccggcgag cagtttcagc agcgtgcttt tgcccgagcc
     7501 agtggggccg acgatggcga tcttgtcgcc tttgcggatg tcgcaatcga catcggagag
     7561 aacgggagcg tcgaacgccg tgtacgagta tcccacgccg gtggcatgca accgttcgag
     7621 tatgccatca cccgattcgt caccactcgg cccaccacat gcggaccgtc cgccgtcacc
     7681 cagtccgacg tcacccggtt cgccacccgg ttcgtcgcat tcaagcgacg caccgccgcc
     7741 ttcaccggcg ggaatcatct cgcaaatctt gcacatatag gtggcgaacg ccatgatctg
     7801 gctgatgacg ccgacgatgc cggagaatgg cgtgacgaat gcggacgcca atgacatgaa
     7861 tccgacgacg gcacccagtg cgagcgtgcc gcgtcccacg aaggtcatgc cgaaggcgac
     7921 cacgcatagc ggcaacacga acaccagcgc cgaggacagg cttgacagca atgccgaaag
     7981 ccgcccttgc cgagtctggt agtcgagctg cgctcccaga cgcgctgacc agcggtcgta
     8041 gcagtggctt tccaaattga ggcttttgac agtttcgatg ccggagaagg tttcgatgaa
     8101 ggcgcgttgc acgtcagcct gcgcgacggt cgcacgctcg accagcgtcc tgttgcgcag
     8161 ggaataaatg acggatacga cgagcaccgc cgcgcacacc gtcagggtca gcatcgtcaa
     8221 tggcactgaa taggcgatca tcatgatcag gtagaccacg aggaacacca tcgacacgac
     8281 cgtcgacggc agactgccgg tcacgatctg ttcgacgacc atgaccaggt tcgcgcggta
     8341 gatcaggtca ccaccggaac ggttcacgaa gaacgggaac tcccgatcga gcacgccggt
     8401 catgtatcgg cgggacaggt atcgtccgaa tcgcacctgc acgcgggtga gcatcacggt
     8461 gttcaacgcg ccgaccgcat agtagaccag cagcgaggca agcagcatcg tcgcgaccaa
     8521 cggcgggaaa ccgctttggg cggcgagcga cccatggtcg accatatagc cggtgcctgc
     8581 gggcacgatc aatgtcagtc cctggacgac gagcgagaac agcaggctca gaccgatggc
     8641 gggcatgttc cggcggagga acccggtcag gatggagacg gttccgctgc gaggccgtat
     8701 gggaatggtt gcgcagccgt cgtttgtcgg ttgcggaatc agcaccgcgc cagaacagtg
     8761 ggccgcgagt tcgccgggcg tataggcatg gcgcccgttc gccgggtcag cgatgcggaa
     8821 tcggccgtat gcgtaatggt cgagcacgac gaaatggttg tcgtcccaat gcaggatgca
     8881 tggcgtcatg acggttttca acgcttcggc gctgggggtc gtgaccgcgc gtacgcggat
     8941 gccggagtcg gacagcaccg ttacgatgtt cgcgaggctc agtccgccgc gtggagcgcc
     9001 gtaccggcgg cgcagctcgt ccatggtcac gggatgcccg aatgcggcga ggatcatcgc
     9061 tgcggcggcc agcccgcatt cgctgtgctc gccttgttcg ataaacggga cacggtgacg
     9121 acgccatgat ctcatgcttg ccgtccgcgc gcgggaaggc cgaagtcgac gtgcgtgcgg
     9181 tcacgcccga gcgtggacgc cttggtgaac gcctcatagt cgtcgaattc ggcgagcatc
     9241 atatccttga cgaggtgttt gtcgtcaagg atgatgatcc ggtcggccac attccaacag
     9301 tattcgaggt catgggtgac ggtgagcaaa gtgcgctcgt cggcgcgaag ctggttgacg
     9361 taatcgacga gcagcgagcg ggtaatcgga tcaatggcgt tgcttggctc gtcgagcatg
     9421 atgacatgcg ggtcgaacag catgccggcg acgatgccga cccgtttgcg cagaccggtc
     9481 gagagttccg ccaccttctt gtcgagatgc ccctccaatt cgaaggcacg gacgagcggc
     9541 tcatcctcca gccgtttcga gtcgacggta tggccgccgt ccgcgattcc cttgccggac
     9601 cggaacagca gttgccggaa gtggatgttg tcacgcacgg tcatcgtgcc gacgagattg
     9661 ccgttctcgg tcatctggaa cacgtcgcgc atcgacggca cccgacgcct atcgatcacg
     9721 catcgccctt cacgggggcg cagcagtccg acgatgagtc tgaacagcgt ggtcttgccg
     9781 acgccgttgt atccgaggat cgccagcgac tggccttgcg gcacggtgaa gtcgatgtcc
     9841 tccaacacgg tctgtttctt cttgtagccg aaggtgacgt gttcgacggc gatgatggca
     9901 tgttcgccgt tgtcggtgcg gtcggcgtgg ttgatgtggt cggcggtcat attgtctttc
     9961 cttgtcgtcg attcggttgt gttcgtatcc gtcatgtccg tcatcgcgtt tccagtgcga
    10021 gtatggaggg cgtggacggg tcgttcagac gaagcatcgt gtaggcgacg ccgaccggcc
    10081 cttggaagta cgacagatcc acgaattcac gggattgcct cagccggaaa cgtcccgacg
    10141 aacgggcctg cgcgatcatg tcgtccatca gacgctgtgc ctgcatgcga taccattcgt
    10201 caccgttggc attgccgatg gatatcaggg tgtcgatcat gccgcatcgt ccatggcaca
    10261 cgccgtcgtc gtcccaatcc gcgttcccaa gcaacgccgt gatatctgcc ttgtctggga
    10321 acgcccgtcc gttttcatcc tcgaagaaac gttcgccgtc cgcgccggca gtggccgcca
    10381 gctcattgcg tgcccagagc acgccgacct tcccacggca ccatttgccg gcgtcctcct
    10441 gtttcgcacc gcttcttcga gcgtccgatt tccgccaaag cattcgggcg aattcggcga
    10501 attcgcgatt ccccgtcgcc gcgtagagct tccagaacgc cacggccatg ccttccagtc
    10561 cgtgcgcggc accggttgga tacggcatgt catcggattc gtcggcgttc cgctgggttt
    10621 cgggaaacgc acggatgacg gttctcccca gccggctggt ttgttccact atgcgcatgt
    10681 catggaatac gtcgtacagc cgcagataca gcatgatcga actgcccgcc ccggtcaggt
    10741 aatccagatg gaatgacggt tgaggattgt cgcgctgcag gagcttcggc agcatatcgt
    10801 cgatgtatgc cggcagcata cgaaccgtct gcgtcatgca acggcgagct tcgggcgacg
    10861 tgatgccggc attggccatg cgtaacgcgc aatagcttcg cgacaggccg gaagtgaagc
    10921 cggaatacgt aatgcctctg tccttgcggc gcatcagact ccgcatcata cgcgtgcaca
    10981 ggtcacgcca gcgctcatcg tgtgtccgcc gatacagttc ggcggcgaac atgcccgtcc
    11041 cggccatgcc gtcgtagagt cccgaagtcg gcgcccccgg ttcgtaccgt tcatccacgg
    11101 tcttgtccgc ggccatggtg tcggatcggt tcgctgtaag ccatgatacg gtgccatcgg
    11161 tttcctggag gatggccgtg tcggctatcc tcgtgccgag ttcgattggg taatgctccg
    11221 catccgtgtc cgacgacacc gaagccgtcg gatgcgcgtc ctccatgccg ggttccatgc
    11281 gcaaggcgtt gcggataatg cgcgattgca atgcggcctg ttcgtcaaga tgcccgatgg
    11341 tgtcaagcac ccgttcgcgt accgaacgtt cgcagacgcc gtcaatggtc gttccatcgg
    11401 gagcgtgcag atcatgtccc gtcagctgtg cggtgaacat ggggatgtcc ccggcgagca
    11461 tctgccggta ttcgcttgcg aagatgcgct tgtcacggaa tgggtagaca tacaggttct
    11521 ccagtatggc ttcgacgtcc agcatgtcct tcaacgccga cggatgatgg atgaaatccg
    11581 caaatcgggc gtaagcgctg gtgttgcgca ccagcacacg cacggtcgta tcctcgccgg
    11641 acagcatcgc atcccattca tccgcgtcga tggtcatcgc cgcggcgacc gtattgcgga
    11701 atccttggag aatctgtcgc ttgtaatgat acggatccac aacggcgtca tccaatgtca
    11761 ccgcgcagcc gtccttgctg aacgtcacgg cgttcctctc gtaatgggca tcggcggagt
    11821 ccaatcccac cggggacgcg acgatgccgg gcatcgtctg ctcaccggtt tcgaaggcgc
    11881 tgatgtcgac ggatgtaccg tcggccgaca tcgccgtttt cgccggcaac agacaggagg
    11941 atgccagtga atcccgcaat atcgtggata cgcggatgtc ggcatcggtg ccgtcgggca
    12001 tgtccatggt cacatggttc gtggcgatcg tctcgaaatc gacgaccatc ggatattccc
    12061 cgctggcgat gatgttctcg tggtgcatgt cgtcgccgtg caggagccat accaatccga
    12121 gcagctgacc gtatctggtg taatagcgct ccacctgacg tgcatcctcg caggtgccgt
    12181 gttccacgaa ttcctcatag gcgtagccgg atttcgtcag cacgtccgac actcgcatcg
    12241 gaaggaaacc cttcgtccgt tcgcatcgcc tcaccaatcc ggcgaaaagc tcatggatat
    12301 gcaggtcacg cggcttgtat acgattttcc gtccgccgat ggtgagcatg gccacggctc
    12361 ttccaccgtc gtgcgcgtcg ccacggtcga tggacatatc ttccaatctg aaatcatcgc
    12421 cgacgcctgc gaaggaggcg agctcgtcgc gatccatgga tacgcggtcg agcatttcct
    12481 tgacgaaatc gatgtaatgg actgtcgtct gcgtgacaaa acgaagcagt accggatatt
    12541 tcgcatacat atggccacgg tattcgtcgg tggccagcag ttcgaaatat cgccgcaatt
    12601 gtcgcttcgc atcgccgtcg cccaacgaac cggcctgacg tgcgacatgc aattcccata
    12661 cgacggtttt caatccgatg cccaacagac gctcgacgta tgcgctcagg cactgttcga
    12721 taaggcgctc gtcattcatc ggcaatgaac aggccgacat atacgcttgc agttccgctt
    12781 tcacgtacgc gacgaacggt gcgaaggcgg tggcataccc cgtgcgttcg actcgctctt
    12841 cctcgctgtc gtaacggttc agaatcgtct gcagttcaac ggaccatgcc ggctcgacat
    12901 ggccgctcag tttccgttcc cgatccgcga tgacggtttc gaccacggat gcgtcatcgc
    12961 cgagcgcgtc ggcgatgcct tgatagtcct cgtcccgcag tgggttccgt cggtttttcc
    13021 attccaccgt tgccgaaagc atgtcttccg cgtgcgatgc ccgatactgt cgcaaagcat
    13081 ccggcatagc ggttgccgcc atgcaccgtt cctcaagggt cgtggcagaa gccgcccagg
    13141 tcgttccaac gttaccgttc atggaaagtc cccctaccgt tcggcgtgga cggattccgg
    13201 cagcttccgc cgcgtttcga cgtattcatg gaacgtcgcg cagtcgaaca tgccgcgttc
    13261 ccgccaatac cgcgattctg catcgctacc gtctcgtcgg gcgtagtcac gcttgtagga
    13321 ttggaatgcc agctcctgcc tttcgctggt ttcaggcacg acgccatccc gcagtgtgtt
    13381 cagcgcccgc acgatagccg cggcggtctg atcggccatt gcctcatcga atggcgtaaa
    13441 agtggtgtgg tatgcggttt catcaatgat gatgcccagt gattccatga accgttccat
    13501 cagttcgccg acttcaagga acccgttggt tgtggcgctg accattgcca tgcccggttt
    13561 gcccgccaga tggaacaaat gcccccaata ggtgagtcga tccatcagaa tcttcatgtc
    13621 gccggaaacg ttatggccat aggtcggcga accgagaatc agataatcgc atcgttcgat
    13681 tgcttttttg acccgggcgg aatcgtccag tccgttcagc tcgatatgat cgacaccggt
    13741 ggaaaactcg ctcgcagtac catccgacgg caagatcgtc gtgtcattcg gcgtcagaat
    13801 cgtccattcc gcgtcaatgt tcgcactgac cgcatcctgt atcagacgaa ccgaccgcaa
    13861 cgtctgcgac tgcggattac gcgaagcgac ataggccacc atgctggtca tggaaatcca
    13921 cctttccaaa agcttcgaat ccagtagatg tcacagctcg atattggtgt tgataaaata
    13981 tcgagagaat actccggttg aaataccgat ggcgaccact accaatacga cataaccaac
    14041 cgagaacagg cacagcggca tcacgttgac gatcacaagc atatatgcca attggagcag
    14101 gaccgcaatc aacaccaaaa ccagttgtgc cattgtcgga tcgctgttcc gggagacata
    14161 aaccatcggc attgcgccca aagaacagac gattgttcct aagactgata cgataagagc
    14221 accaattgca tcatctgctc cagcggttat ctgaaagcct gatgacaaaa cacgcataaa
    14281 agccagattc aaaagcacgg aaatcactgt caggataaca ggaaacaggc atttacacca
    14341 gcagtagctc caataggaac gaccagactg tatatagagc tcaaacagtc catctcggaa
    14401 atcctgatac aggatggaga ccatcaccga gcatgacgaa tagatgaaaa acggtccaaa
    14461 aaagacagcc caagtaaatg ggtctagaat gcctgcgcca ctggcaacca tctccacgaa
    14521 tattgccgtg accataatga taagaaccat accccagttc ttgaatgact ggaaacatgc
    14581 cttgcagtca cgaaacagaa tcgccttcat gccacttccc cttaacgata acaagtgtca
    14641 ggtatgggtc ggatgtttta cgcaatccat acctgaccca tgtaaagcaa cgttcacttg
    14701 cagttcccac aggatgcaag tcgggtgacg accgttgccg aacatgccga gaaagacacg
    14761 ctcagaacgg aaaccgcgaa cgacagcgac gccggcgcga cgccatcatc gttgcgaccg
    14821 gtcagcatcg ccatatcggc cgccgacaga tcctcgaagg attcaccgac aatggacttc
    14881 tcattgatgc tcatataggc ctccttacct aattcctgcc cttcaggcga agagctactg
    14941 taagcatgac gcgctttctc ccgcttcgca atgactttta tgccattagg ggacaaggac
    15001 ttttatatga atccatgttg tgcaatgatc attgacacac cccgacgcaa aggaaccctc
    15061 atgagaacac cgcttttaat acttacggta cttggtttga cattcggagc gtcagccagc
    15121 actccaagca acagttcaac ggaggaagaa atatcaacat attcactatg ccctgtatgg
    15181 tttccattat gccatatcag aaattaggtc agtagcggta acatgcaata gaaagaccat
    15241 tcttcgccgt ctttttcata tctgatgaat cctccttgtc cagatatcaa acgggaatat
    15301 atacttagcc cttttcttgc tcccaaagtc acacatcgcc gactcttttg tcgacattta
    15361 ttcacctgaa caatatcaac agcattattt gaaaatgtga caatgacgga atattcactt
    15421 ttgtcagcat agcgttcaat attcgtgtaa atttcacgca acaggttaac gattatttga
    15481 ttccacgagt tcaacattgc gctggataca ccgcgaagag atgaatgacc gcaaaaccct
    15541 ttgtcatgca accgacggtc actttcactc aatgtagctt gaatatgttc ggcaagactt
    15601 acatgaaata catcatcttg tttatggtca tcatccgata gataattcat aaccgaatgc
    15661 agatcttgga atatcctatt gataccgttc tgcaattttc tccatcgctt aagctcttct
    15721 tccttcgatg catcaatacc ttcctgcact atgaccaaca ttcgtgtcaa ctcaccagac
    15781 atggcatcat gcatcccctc agcaagctgt aagttatatc gaacaatttc agctttcttt
    15841 tctaactctt ttttcttttc aagtccgttc ctttgccgta gccaaacccc taaaagaaac
    15901 acaaaccaaa gcaacaccac caaattaatg gaaccatcga acgaaccaaa ttcactattc
    15961 tcccgatata tcgcataatt cagcaaagcg ctaatagaca acagcaccgt tgccgtcaca
    16021 ccattccacc aaacagcagc atagccttga atcgcaagag ataccagaac accccatgac
    16081 tcatcgcatt gcgataagca aggcatcaat tcattcagga atgcgatgac gataatcccc
    16141 catgttgccg gtaccggata taacggcaac atactcacag caagcatgta cacgatgcga
    16201 ataaacccat cattcaaact ctcaggagaa tcaagaatcc attcggcgat acatgcggca
    16261 agacatgtca tggccactat cgatagaaca agattttttt tcgatactcc caagcatttc
    16321 ttgcgaacca caagtatcgt tttcattgcc aatcgtctca ccatcgttcc cgcctccacc
    16381 aataggcaat cagttcggct ctggaagtaa gatggagttt gttctgaaca cggtcaagat
    16441 aggttttcac cgtccctgcc gaaacatcca tcatccgggc aatctgagtg ggcttatacg
    16501 actgtgaata tagttccatg gcatattttt cccgttccga caatctttcg attctattca
    16561 cgggaagtcg aaccagacga tgatatgcag catctacatc ctcgaatcca atagtctccc
    16621 ctcctactcg aacacagaga gtatgaccat cgctgacgag cttgaccgct ttacacagtg
    16681 ctggaaaatc agcttttgac acaatgcctt gagcaccacc ctcagcagca cgtcgcgcat
    16741 agcgagttaa actgaacgat gtcaccgcca gcaacggcaa catcctgtta cgacttctga
    16801 tttcccggca caccatgtct ccgggcatgt cctccagact catgtcaacc agcagaatgt
    16861 ccgcttcatt tgcgggatcc gtcgcatatt ccagagcatc ggttccggta ttcgccttcc
    16921 aagctaaccg aacattcggc agatgacgcg acaagaacgc tgccaaaccc atcagcacga
    16981 agtcgtcgtt atcgactatc gccagtctaa tttcatttgg gttccccatg gtgcacatga
    17041 tagacgtttt tcgtacggac atgcccgccc cgttgtctaa ttgaaagtgc aacacccgtt
    17101 agattggaga ttgtccggat aaccagtccg aagggatgtt gcacctatgg gagaagtgta
    17161 ttcgcacctg tcggaagagg aacgccgggt catccggatc gagatcggca acggcaccat
    17221 catctgcggg atcgttctga tgctcggccg caacgcctcg acggtcggca gggagatcaa
    17281 acgcgacacg tggttcccgt ccaacgagaa cgagtcctac cggccgtacc ggccgaaacg
    17341 gctgaagacg ggcccgtgga cgggcagata ctacatcgcc ggccccgcgc agcgcaaggc
    17401 cggccgcagg cgcgccgaac cgcgcaggcg ccaccgcctg tcatgcgaac gcctgtgggc
    17461 gcgggtggcc gaatggctgg gtcgcggctg gtcgctgctg cccgtcagcg gcaggctgcg
    17521 cgtcctgttc cccgacgact ccgccatgcg cgtgtgcccg gagaccgtct gccgttggat
    17581 ccacgccgac cgccgtcgcc gtgaacgctg ggcgcgtcgt cttccacgtg gccacgggag
    17641 gcgtcgcagg cgtggcggcg ggaggacgtc gcgtttcccg attcccggac gggttcccat
    17701 ctccgagcgt ccgccggagg ccggagaccg cagcggtttc ggccattggg aggccgacgg
    17761 cgtgatcggc gccggatgca acctgcacac cgaggtcgag aggaagacca ggttcctcat
    17821 ggccgggatc gtgcccggca agaccgccgg ggaaagcgtc ggggcgcagc tggcgatgtt
    17881 ctcgccgctg ccggccggcg cgcgcggcgg cgtcacgcac gacaacggca ccgggttcgc
    17941 ccgccacacg cgcctgcgcg acgggctggg catggacacg tgcttcgccg acccgtactc
    18001 cagccggcgg cggggaagca acgagaaccg gaacggcatg atccgccggt atctgcccaa
    18061 acgcagcgag atccggatgg acatggccgg ggaactgcgg gagattgtcg acgaggccga
    18121 caaccgtccc atgcgcgtgc tggactaccg gacgcccgcc gaggcattcg ccgacgaact
    18181 gctagaattg caggaccaac agggggtgtt gcacctctaa atagacatcg ggcacacggt
    18241 ttgcgcggcg gtgagcagtg agcggtgagt actgagcgac gtacggcaac tcacgtgcgc
    18301 tcacacagtg gtgagcaatc cgccaaacaa caccacgagc agagcgatgg tttcaatcac
    18361 gaagtacaga atgaaacttg cccagctttt ggtcagtacg ttcagtggtg aggtcttccg
    18421 gataatcacc agcagaccaa caaacaccag ggcatatacg gcgatgccga tcgccgcacc
    18481 cataatgccc agattcgcgg cattcgccag gccggcctgc ttaccgtaga ccacgtacgt
    18541 ggaataccag aaattgagat tgagcatact gagtcccgcg atgaactgct cgccggccaa
    18601 cccgatcacg aacacgatca accacggcca ggacggcgag acgaccaccg ccatcgccaa
    18661 tccgacgtac gcaatcacca cggtcaccca accgaccagt gcgatgcctt gcggagacac
    18721 tcccccgagc acggccacaa tggagtcagt attatttacc gccaacgaac ggccgaacca
    18781 gtacggcgcg atgatggcgc acagtacggc aagaataatc agcgcccaac gcaacggatg
    18841 cgaacgacgg cgctcgatat ccgccagaga caaatcggtc tcgggtatgg aagcctcggg
    18901 gtgcttggaa acctcgacgg tctctacttt gccgcctacg atttccgtcg cctcgttagg
    18961 ttcttgctcg ttggattcct gctccatgca ccgcctcgcc gattacctgc tcattgccat
    19021 gtattgcgat gcccatctta gcgtgcgtgt tgggcaagtc tccgatacga tcgattactc
    19081 gccatggccc tcaccatgat cctcgctacg attctcctta tccgaatccg cgggagcaac
    19141 gtcattattg cccgcagaca agccccgctc gcccgattcg cgtttcggaa gcaagaaaga
    19201 tgatgccccg ctcccccgtc gcccgctatg cagcaaagcc tcaagcatat cgacctgccg
    19261 ctccagctca tcgatacgac gtacttgctg tgcgatcagc aggtcacgta aatcgttgtt
    19321 ctgctctttg cgggagatgg ggaagatgat ggcgcggcgt tcgggggata cgtagaaatc
    19381 ggattcgctg ccggctttcg ccgtaatcgc ggcactctcc gcctcgcgcc actcgttcga
    19441 agtacaagca gccactgcgt atcgttcacc gcaatcgcac gcccccacca atacggcacc
    19501 acaatggccg caatcaccag cagcgcataa gccagccaca atgcaggatg cgagcgctta
    19561 cgctcaatat cggccagcga cagcgtcgat tcgggaatgg acgccaccgg atgcttggaa
    19621 acatcgttat gtttggaaac atcgttgggc atgggcgaaa caccatcgga ccgcgtatcg
    19681 atttcagcct gcacctcacc gctcgcctgc tggtcgaccg gctgtttctc cacgctggaa
    19741 ttcaccgcca tctacgttta cctcgcgttc gttgttcgac gccacacctg tctgcacaat
    19801 gcgtcgtctc atgccgcgac gcccatgcta ggacggtatt gtatcgtgag tgcgccatac
    19861 gataatgaca tggcgccgga cataacgccg caatacctga ttttcgctaa tcgcaaccat
    19921 gcttcggcgg acgacataag ccatacatat gttcataagg acgaaccata tccgaattac
    19981 tcactccgct aacatcacca cataacggca acatagatac acagccatac ttgatatcag
    20041 gagaacgccg tcgattcgaa atgaaaactg ccagccgccc acacaccagc tcctttgttt
    20101 ccaaaatcgc acattctacg ccgatgtcat gctccaccat gtctcacgcc gcggtctcaa
    20161 cataacagga tgggttgtac gaatccacgt tgccgagcat tcgcacaacc caccattgcg
    20221 acacatcact gattccgcac attcaatcgc tgcaaccaac aggctgcggc gatatttcag
    20281 cgcgaagagc ggcgtatccg aatgacactg atgccagcca gcatcagggc aattgcagac
    20341 agcaccatcg gtgttacgga cgaaccagtt gatgacagtt cagatgaatt atcatcagca
    20401 gtagaagact gttgctggcc gccatcaccg gtctgatcgc cgttacccga ctggttaccg
    20461 tcactggtct gatcaccacc accaggattt ccgccatcac cagactgacg gtcaaccgcc
    20521 aattgcgcga gctgcaaact cagtgcacgc tgcggggcat ccacctcatt ttgcgtggaa
    20581 ggatcggatg ccaacgcctg ctttgcctta tcaagtagcg tgagcatctt atcccactca
    20641 tccataggat attccgcaga ctgcagagag tcagcctgat caatggccga acgcagctta
    20701 gacgtatcca cagctttgcc gtcagaagtc aacacgtcgc tcaagtcata gtaatcaaaa
    20761 tcgacataac cacccgtatt ctccttggcg taattgaaca agccgattcg atacccctta
    20821 aagtgcgaca agctccaatc gtaagtcagc ggcccctgct cgtcgccaag cttggaccat
    20881 tgcttaccgt ccagactgta ccaatactga atcgtcaact taccactcgc attatccagt
    20941 gtgttgtccg acttgatcca cacattggtc gcatcatctg gcaatgtcac tgtgccgccc
    21001 gatacaaagg cctcttcagc gtcacgatca atcgtatcgt caacgatatt accgtccgcg
    21061 tccttcacgc cattgtcgta gacacgcttg accacgccca acgttcgctg tccattttct
    21121 tgacgcacag cggcataggc aaaactacgg gtatatgtag cgaggcctgc ggtgtctcca
    21181 tccttcatat gactgacatc catgtgggtt tccacagaca tggatccgcc aaaggtacgc
    21241 tgcgacaaaa cgttacgggc ggtttcaaaa tatgtcaggt cgccataagt gcctttcata
    21301 tatttggccg tggcggaaac cttgtgccca ttggtcaaac gcaaccagcc ttcacgatca
    21361 gtgagagacc aatatcggtt atctggatta tgtccccatt cccataccaa atcaagattc
    21421 gaaccattgg gttggtattc ttcggcgacc ggatattcct tctcatcagc aagaccgatc
    21481 agggaaatat cgtcgatgac gtaatccatg cacgtgcctt ccgcacccca cgcggtttcg
    21541 acaatgagtt tggaaccttc cacattagcg tcggatggga tggagaactc acctgtgata
    21601 gtagtcgtct ccccacgttt cactgttcct gtggccacac gattaattgt gccgtctgca
    21661 tattgaatcg ccacataaaa caggtgggaa gtcacagccg atgaatcgac gccgtccatc
    21721 tcatggtcgt atcgaatcgt tgcactggca cgatatgtca cgccctgctg caattttcca
    21781 tccatagatt gacccgggcc agcgccattg tattcgccac gattcgtcac agcaagactc
    21841 gtggttccag aaagagaacc atccgtaatc gcggtaagcg taccattcca ctgaggggtc
    21901 cacgattcag tcccgttttc gaaatcgcca ttgtccacca gctcgattcc aatcagagaa
    21961 tcgtcaacct gaggaggctc ctccagagtc caccaatcct gatcctgata agactgatga
    22021 ggcgcgtcat tatcaaaatc gtccgaattg accagggaac gctggcgaac cagattctcc
    22081 aaatcagcag gcaaatcaat cagtttgtcg taggtgtccg acgcgcttac ctgattattg
    22141 tccccaaaca caggccatcc gtcatcaccc cacgttgcag gaatcaaacc gggaatacgt
    22201 ccggtcggat atgtgtctcg gaagaagaat ccatgccaag acgtcgtgcc atcaccgttg
    22261 tcgacttcaa caaggctacc ttgtgcgaaa gcacctagat aatacttttt ggcttcgtat
    22321 ttggagccat caagcaaatc agtggtgcgc agcagcatca ccgtacgacc gtctttgccc
    22381 cagtaaatcg ttggagtata gaaataatca ccgattttga aagtctgaga tccttcaaat
    22441 ccggtaggag tctcaccaag atcatcagtg aactgttcgg cagagatgat attctcatgg
    22501 ctctccacca ccgtggttaa atcatcggac agcctatatt ggttgacgcc ggagataatc
    22561 caaggactcc cttgctcatc aaaatacaat gacggatcat ggaatccccg attaagggca
    22621 atcttcgtcc aaggaccatt ctcaatatca tcggtgtagt agatataagc gccattaagg
    22681 ttgttcgtat tgaataacac gtagaagcgg ccattgtgat agcgcagcga cggagcccac
    22741 tcgccttcgc catacgagct agctccattg cgcaaggatg aagcatcgct catagaaatg
    22801 cgatcataca cgtacgtgac tatccaccaa ttgaccagat cataggattt cataattgga
    22861 gatccgggac tgagctccat agtggtactc accatgtaat acacatcacg accgtctttg
    22921 ttattcggat cgtccttcga cacacgaata acactgatat ccggaacatc cgtgttcaac
    22981 atgggaatgg aatacgtgcc atcaccgcta tcagtcgtgg tgtaactgcc atccgatggc
    23041 gttgaagatg gcgttgaatc atccgcaaag accggcattg gcgccaaaat caacccacaa
    23101 gt
//
