LOCUS       NZ_JADKRR010000005     11577 bp    DNA     linear   CON 16-AUG-2024
DEFINITION  Clavibacter sp. VKM Ac-2872 n5, whole genome shotgun sequence.
ACCESSION   NZ_JADKRR010000005
VERSION     NZ_JADKRR010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Clavibacter sp. VKM Ac-2872
  ORGANISM  Clavibacter sp. VKM Ac-2872
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1  (bases 1 to 94384)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Draft genome sequences of plant-associated actinobacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 94384)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2020) All-Russian Collection of Microorganisms,
            G.K. Skryabin Institute of Biochemistry and Physiology of
            Microorganisms, PSCBR RAS, pr. Nauki, 5, Pushchino, Moscow Region
            142290, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 675x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015351105.1-RS_2024_08_16
            Annotation Date                   :: 08/16/2024 04:34:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,385
            CDSs (total)                      :: 3,333
            Genes (coding)                    :: 3,309
            CDSs (with protein)               :: 3,309
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 2 of 24
            Pseudo Genes (incomplete)         :: 19 of 24
            Pseudo Genes (internal stop)      :: 4 of 24
            Pseudo Genes (multiple problems)  :: 1 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:57:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 82807
            Orig. end                         :: 94384
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADKRR010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11577
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11577
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11577
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:6671](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6671)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    968..981
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            1211..2272
                     /locus_tag="ITJ40_RS16420"
                     /old_locus_tag="ITJ40_16420"
     CDS             1211..2272
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017887561.1"
                     /locus_tag="ITJ40_RS16420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_16420"
                     /product="YdcF family protein"
                     /protein_id="WP_228512745.1"
                     /transl_table=11
                     /translation="MISTVAWSSAGIALIFGVLYIAGRRHDARMLRNGIFLVAMFASAA
                     LALLLGLALSVPAIAVIISLLVALLIPLAGFILAVVLIVNGVQMMRLEGRSISNLLSFM
                     AGFLLLLVPAALVGGVALASDMKATDPAFIALFILELLLFLVPSYFAVSFVTFTVYSIV
                     YSRTRHRMVPDAIVVLGSGLIRGQVPPLLRSRLDRALQSYAAERAMGRVPLLIPSGGQG
                     HDEPRSEGAAMAEYLITHGALSEHVLPETASRNTQQNLSFSRKVQLDAGRDGQIMVVTN
                     NYHVLRTAVLARKLDLPAQVVGSRTARYYVPSAFLREFIAVTVEHRWLNVAACAPFVLL
                     ALYPLIEYWNGQT"
     gene            2358..2612
                     /locus_tag="ITJ40_RS16425"
                     /old_locus_tag="ITJ40_16425"
     CDS             2358..2612
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ITJ40_RS16425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ITJ40_16425"
                     /product="NrdH-redoxin"
                     /protein_id="WP_194668096.1"
                     /transl_table=11
                     /translation="MASEVLVTGVPSSAGFRDTLRRFEEKGIDYRVTRAVDGLDRGYQT
                     VVVQAGAAVWTGFRPELIDALAHPSVEEDGHRYSGTAPQ"
     gene            2733..3518
                     /locus_tag="ITJ40_RS16430"
                     /old_locus_tag="ITJ40_16430"
     CDS             2733..3518
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019135294.1"
                     /locus_tag="ITJ40_RS16430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_16430"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_194668097.1"
                     /transl_table=11
                     /translation="MKTPILHASGLVLRYGESPAIDGIDLRIHQGESIAIMGPSGSGKT
                     SLLHCLSGVLRPDSGTVTFSGLSGVVEICALSDGKRSQMRRQDFGFVFQQGLLVPELTA
                     VENVALPLLLSGADRRGAEKHATSWLAALGLAGMEQRRIGELSGGQAQRVAIARSQVSG
                     ASLTFADEPTGALDSATGVGVMDALLHSTVAQGRTLMVVTHDESVAARCTRIVRLVDGR
                     IISDSALDASAKPPTTSVPRLYPRHGGSAPERDGRDGLS"
     gene            3668..4930
                     /locus_tag="ITJ40_RS16435"
                     /old_locus_tag="ITJ40_16435"
     CDS             3668..4930
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020076594.1"
                     /locus_tag="ITJ40_RS16435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_16435"
                     /product="permease"
                     /protein_id="WP_228512747.1"
                     /transl_table=11
                     /translation="MTALLLTVVGGALMFWSWTGRDASVYQVMAWIALSLLVVPIMALG
                     GAAARLATRRRDDRLATLRLLGATTLTITLMTVLESTALAVIGSVIGVVVYVVDMPLIG
                     LIPFHGRPIGPVAIWAGPAVTAEMVAGVAALAIVSSVVGLRQVIVTPLGVRMKQRPPRI
                     SRLRLFVGSLLIVGAFLAVTHHDDFSRIVSVAVIAVAFSVAIAAFNISGPFVLSVFARR
                     KVRSAKKAAHLLSARGILESPKSSWRLVSGVAMTSFTAVVMGSGAALTMQGESGAPSDY
                     LTMDIRTGLLITLVASFLMVASSAGVSQAAAVLERRDLYVSLDRIGMPVSEMDRARVRS
                     VMQPLVFVSLTSAAVGALFISPFAGLALAGGGIDPTALIRDAVLVTGSCIVSGIVLVRL
                     ALLATRPILVNVLAHPERSLG"
     gene            complement(5001..6671)
                     /locus_tag="ITJ40_RS17505"
                     /old_locus_tag="ITJ40_16440"
     CDS             complement(5001..6671)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="ITJ40_RS17505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_16440"
                     /product="YcaO-like family protein"
                     /protein_id="WP_194668098.1"
                     /sec_met_domain="YcaO (E-value: 8e-29, bitscore: 93.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPRDPYRAYVEICIELGLLPAERHIFVVASASLDEMHARACLFG
                     SGHVTWALLRTDERDACTRCLSTIPAFLEHHYGTGAAPGPHDSGAREIVQAFHNLHDLS
                     MAVTDAYASQDWSCIRPVAGCPNCSGRGRPVVPPTFASMVTMETTGGLESSDDDRASRA
                     ASFVSRMRWAFGFASIAGNPTTARRSRGVSLATAPIRDAFDPDLAGMARGKGATDAEAL
                     ASCLGAALERYTLGQGTHPLVVEASALELEGAVDVERVFGLAHVDAPLGMPHSMALSRE
                     WMPAVDILEGRSVYVPAALAIHRHDPRRASQIAPSDAGGAACRASAVEAFHLGLREVVE
                     RDAFQYYARTEALPTPLGWALVPEDVRDAMSAVDARFSVTLLDNPFDAPVVTVAMVCGA
                     SHRARASFGSAFASTLSASVRDAFLECMSMLHSLDARVAIAPRDTDMRNLWFTGSAVDA
                     LPGLFPDMHDGPEVGVADLGLHERHELRQLLIDAEAQGMSVFDIPLVEERGIAVHKVVM
                     SGTALEETTCSSPSRRLQRFAMFLGHPAPRLRYGGPLVV"
     gene            complement(6787..7155)
                     /locus_tag="ITJ40_RS16445"
                     /old_locus_tag="ITJ40_16445"
     CDS             complement(6787..7155)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023202.4"
                     /locus_tag="ITJ40_RS16445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_16445"
                     /product="Lsr2 family protein"
                     /protein_id="WP_194668099.1"
                     /transl_table=11
                     /translation="MATNDMSHTFDDIDGSMLDDLNPGETVRFGIDGLLFEIDLSITHA
                     AELRQAFEPYLDAARRTPSRPSRHADRTTVQTRERADAHAWLRENGLPVGGRGRIADPL
                     LARDREQGRATPTARRRG"
     gene            complement(7671..7928)
                     /locus_tag="ITJ40_RS16450"
                     /old_locus_tag="ITJ40_16450"
     CDS             complement(7671..7928)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ITJ40_RS16450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ITJ40_16450"
                     /product="hypothetical protein"
                     /protein_id="WP_194668100.1"
                     /transl_table=11
                     /translation="MPIGRTPHRKRHRTKAYHWYRRRRAGASEVYIAFVPEAIREMDRM
                     RRRRMRDAQTQYRARDHGGLRGRFIRVIRAFRTIVGRHAR"
     gene            8543..>11577
                     /locus_tag="ITJ40_RS16455"
                     /old_locus_tag="ITJ40_16455"
     CDS             8543..>11577
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013508.4"
                     /locus_tag="ITJ40_RS16455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_16455"
                     /product="beta strand repeat-containing protein"
                     /protein_id="WP_370532080.1"
                     /transl_table=11
                     /translation="MLAIALITSSLTLGSGLFGPAPAAQAAAGNPGVPSAPTTLYTEDF
                     ENAATATAIPLTSYTGATGTTYNSDGLYGDQGECNGLVLNPNSAFAGNQCVNGPNSVNN
                     KATLKNMVGALGALNGTGAANDAVSAMTASQNVPPNTVEFRTTKQIALPAANGRFITLG
                     VSVAAACGDGGADFNQPRLAFNFVDSAGRETSATNNPVNPCGGATQGILAKALVSDKGI
                     LFSGSSVGINMRNVDGGGNRGNDHAFDDIKILDVTPQLDKSFSPASARTGGNSTLTFTI
                     TNTSELGQKNGWSFTDALSSGLTISNPSAATTTCASGVVTAPAGGTSVAVTGNLNAGQT
                     SCTVSVNVTSNTAGTYTNGPQNVTTTGLNPPGTSTVTFSNPSVGVIKRAGTPVDVNGNG
                     VTDAGDTIQYTFDVTNTGDVPLSNVSVTDAKAGTVTCPSGTLAPQATVTCSAAAPYTIT
                     TADQNAGAVNNTATASGTPPNSTTPVTSTPSTTSTPVTTPVQSLTLDKTATPSDAASFT
                     VGRQITYSFLVTNTGNVALNDVSIDETSFTGSGTLSNATCPATTLAAGASTTCTATYTV
                     TQADVDAGGVTNTAVANGTPQGSTTPIPSNPDTVVLPGLSTPSITLQKTASPTTISAAG
                     DVVTYSFAATNNGNVTLTNVTIDETQFSGTGTAPVITCPSGAASLAPGASVTCTATYTA
                     TQADVDAGQITNTATATGTPPRGPAVTSDPSQAVVTADPNPSVAVVKSANPSSIMNAGE
                     TVDYSFVVTNTGNVTLTNASVSETQFSGTGTAPVVSCPDAAASLAPGASVTCTASYVAT
                     QADVDAGSITNTATATGTPPSGDPVTSDPSSAVVTAGAAPGLTMVKSANPTAVSKVGDT
                     ITYSFLFTNTGNTTLTNITVNETAFSGTGTPSAVAYPTRTLAPGESTTATATYVVTQAD
                     VDAGKVDNSATGAGTPPGDTPVVVTPPSDVTVPIDPAPGLTMVKSANPTTVSKVGDTIT
                     YSFLFTNTGNTTLTNITVNETE"
ORIGIN
        1 tccgcatcgt cggtgacgta tcccgcttcg gtcagggcgt agatcgcctc tctgcatcca
       61 gccgccgata tgtccagcgc ttgccggagc tgatcgaacg tcatcggccc gcgtagcagc
      121 tggcgcagca cggtcacgcg agagggggct tgggccagca cctggaacgc gatcacgttg
      181 cggggtgcgc cttgctgtcg catcaggtcc ttgggcatgg ggtggattgt ctcgcgttgc
      241 gcggaacccc atccgactca tcgcgagaag cgatctagta ccagggtgaa atgcggtgtg
      301 agtatccggg cgagcagcct gccgcgcgtg cgatggcccc tgaagatcgc ggttaccgct
      361 tcaacccaag gggcatccgg ccctgcagtg accatccacg aaggtgtgct caaaatggca
      421 cgaccgactt gcttgtcgga tggcaccatg caaccatcga gcgacgtcgc ggtggtccca
      481 tccccccttt gaggccaccg ccacgtcaga tcgccctcag cccgaggaac cggatcgtgg
      541 tcagctgagg tggtcggttc cgcgtgatgc gtgcggcacg ttccgctgac tgcgctctta
      601 atgcggaatt cgctagccgg cctcgaccgg gtgctctggt cgaggctggt ccgccctctg
      661 gggccgaagc ccgtccttcc ctgccgggcg tagcgcgaac gcacgccgag cagaccctcg
      721 tcagtcggca cgatcggctc caggatccgg catgagggtc ggccgagggc tcgagcggtc
      781 gcccgggaac atgctcggca gcatcacgct caacgaagaa cccgaacagc gaaaagcgag
      841 acgacgcgcg cgatgaccga gaaagcgctg ccatggctcg cctggggatg atctcctccg
      901 tgaggcatgc atttcagggt gaggtgcggg gtgagagtgc ggcgagatga tggtgactcg
      961 tgatggattg acgcagagca ggtggcaagc ggcccatcga ctgtacgcat gatggacagc
     1021 gactgcattt catcgcgtag ggtaccctcg tgcccaatga tcccgtcagt cgcgccccag
     1081 gcgaccgacg catgcgattg aatggcccgt tctggggctg gccggaagtc atcagaaata
     1141 gcctgacgag caatgggaag agtgacgaga tggtccgttc gctcgatatc gacggttaca
     1201 ggggcaacaa ttgatcagca cggtggcatg gagcagcgca ggaatcgcgt tgatcttcgg
     1261 cgtgctgtac atcgcaggcc ggcgacatga tgcgaggatg ctccgcaacg gaatattctt
     1321 ggtcgccatg ttcgcgagcg ctgctttggc gctgctcctc ggtcttgcgc tgtcagtgcc
     1381 ggccatagcg gtcatcatct cgctgctcgt ggcgcttctc ataccgctcg caggtttcat
     1441 cctggcagtc gtgctcatcg tcaacggcgt gcagatgatg cgcctcgaag ggcggagcat
     1501 cagcaatctc ctgtccttca tggccggttt cctcctcctg ctcgtgccgg ctgctctcgt
     1561 cggaggcgtc gctctcgcga gcgacatgaa ggcgactgac cccgcgttca tcgcactgtt
     1621 catcctcgag ttgctgttgt tcctcgtccc ctcgtatttc gcggtgtcgt tcgtcacgtt
     1681 caccgtgtat tccatcgtct acagcaggac ccgacatcgc atggtccccg atgcgatcgt
     1741 ggtactggga tccggtctga tccgcgggca ggtgccgccg ctgctccgca gccgcctgga
     1801 tcgagctctg cagtcgtacg cagctgagcg ggcgatgggt cgcgtcccgc tgctgatccc
     1861 ctcaggtggc cagggtcacg acgagccccg ctccgagggg gccgcgatgg ccgagtacct
     1921 gatcacgcac ggggcgctgt ccgaacatgt gctccccgag acggcgtcgc ggaacacgca
     1981 gcagaacctc agcttctcgc ggaaggtgca actggatgcg ggacgcgacg gtcagatcat
     2041 ggtcgtgacg aacaactacc acgtactgcg cactgccgtc ctggcgcgga agctggacct
     2101 gccggcgcag gtggtcgggt cgaggacggc gcgttattac gtgccgagcg cattcttgcg
     2161 cgagttcatc gcggtcacgg tcgaacatcg atggttgaat gtggccgcgt gcgctccgtt
     2221 cgtattgttg gcactgtatc cgctgatcga atactggaac ggacagacgt gacgacggag
     2281 tgctgcgagg ggccgcgacg aaggaagccc tggctgggca ttcgcggcgg agatgcggcg
     2341 acgagaggga gatcgtgatg gcgtcggaag tgctcgtgac gggagtgccg agcagcgcgg
     2401 ggttcaggga cacccttcgt cgcttcgagg agaagggcat cgactaccgt gtgacccgcg
     2461 cggtcgatgg cctcgacaga ggatatcaga ccgtggtggt gcaggccggt gcggcggtat
     2521 ggaccggatt tcggccggag ctcatcgacg cgctcgcgca tccgtcggtc gaagaggacg
     2581 gccatcgata cagcggcacg gcgccgcaat gacggcaacg gaaaggtcgg cgatctctcc
     2641 ggggaatcca tcgccgtcat cgagagtatg acgcgagatg gtaccggagg aggacgcggc
     2701 ggcgatgcgc cgaccgggaa gctgattcgg tgatgaaaac tccgatactc cacgcgtcag
     2761 gtctcgtcct ccgatatggg gagtctcccg cgatcgacgg catcgatctc cgcatccatc
     2821 agggcgaatc catagcgatc atggggccct ctggctccgg taagacgagc cttctgcact
     2881 gcctttccgg tgtgctccgt ccggattccg ggacggtcac gttcagcggc ctgtccgggg
     2941 tcgtcgagat ctgcgccctc tccgacggca agcggtctca gatgcgtcgg caggacttcg
     3001 gcttcgtctt ccagcagggc ctcctcgtgc cggagctcac tgcggtcgag aacgtcgcgc
     3061 ttccgcttct gctgtccggc gcagatcggc ggggggccga gaagcacgcc acctcctggc
     3121 tcgcggctct tggtctcgcc ggcatggagc agcgccggat cggcgagctg tccggagggc
     3181 aggcccagcg cgtcgccatc gcccgctcgc aggtcagtgg tgcgtcgctc accttcgccg
     3241 acgagccgac cggtgctctc gactcggcga cgggggtggg cgtcatggac gcgctcctgc
     3301 actcgacggt cgcgcagggc cggactctga tggtggtcac ccacgatgag tccgtggctg
     3361 cgagatgcac gcgcatcgtg cgactggtcg acggccgcat catcagcgac tccgccctgg
     3421 acgcttctgc caagcccccg accacgtctg tcccccggct ctatccacgg cacggtggct
     3481 cggcaccgga gcgcgacggc cgcgatggtc tctcatgacc gacaccgtct cgcgcccggt
     3541 gccggccgcg gacgcgatcc cgcggatgac aggtcgcccg tcgatccccc gtcttgcgtg
     3601 ggctctcgcg cgcccggggg cggtgagccc cgccactgtc gtgctgccga tcgtcgcatt
     3661 cgccgtcatg accgcgctcc tgctgaccgt cgtcgggggc gcgctcatgt tctggagctg
     3721 gacgggtcgc gatgcgagcg tctaccaggt catggcctgg atcgcgctgt cgctgctggt
     3781 ggtgcccatc atggcgctcg gcggcgccgc tgctcgtctt gccacccgcc gtcgtgacga
     3841 ccgcctggcg accttgcgcc tcctcggcgc gacgacgctg accatcacgc tcatgaccgt
     3901 cctcgagtcg acagccctcg ctgtcatcgg ttcggtcatc ggcgtggtcg tgtacgtcgt
     3961 cgacatgccg ctcatcggtc tgatcccgtt ccacggccgg ccgatcggac cggtggcgat
     4021 ctgggcggga cccgcggtga cagccgagat ggtggcgggc gtagctgcac tcgccatcgt
     4081 gagctcggtc gtcggcttgc gccaggtgat cgtgaccccg ttgggcgtgc gcatgaagca
     4141 gcggccgccg cgcatctcca ggctccggct gttcgtgggc tccctgctca tcgtcggcgc
     4201 gttcctggcg gtcacgcacc acgacgactt ctcccgcatc gtctccgtgg cggtcatcgc
     4261 cgtggcgttc agcgtggcga tcgccgcatt caacatcagt ggcccgttcg tcctgtcggt
     4321 gttcgcgcgg cgcaaggtcc gctcggcgaa gaaggccgct cacctcctgt ccgcgcgcgg
     4381 aatcctcgag tcgccgaagt cgtcgtggcg cctcgtcagc ggtgtcgcga tgacgagctt
     4441 cacggccgtc gtcatgggct ccggtgccgc gctcaccatg caaggcgaga gtggtgcccc
     4501 ctccgactac ctgacgatgg acatccgcac gggcctcctg atcacgctcg tcgcgtcgtt
     4561 cctcatggtc gcgtcatccg cgggcgtgag ccaagctgcc gctgtgctgg agaggcggga
     4621 cctctacgtg agcctcgatc gcatcgggat gccggtgtcg gagatggacc gagcacgtgt
     4681 gcgctccgtg atgcagcctc tcgtcttcgt gtcgctgacg tccgctgccg tgggcgccct
     4741 cttcatctcc ccgttcgcag ggctggcctt ggcaggggga ggcatcgatc cgaccgcctt
     4801 gatccgtgac gcagtgctcg tgaccgggtc gtgcatcgtg tccggcatcg tgctcgtccg
     4861 cctcgccctc ctcgcgacgc gaccgatcct ggtgaacgtg ctggcgcacc cggagcgctc
     4921 gctcggatga cctcggtagg ggatcctgcg cgcttcaccg agcgacgtcg atcacggggg
     4981 tggaggggcg ccgcctctcc tcagacgacg agcgggccgc cgtaccgcag ccggggtgcg
     5041 ggatggccga ggaacatcgc gaagcgctga agtcgacgtg agggcgagct gcaggtggtc
     5101 tcctccaggg ctgtgccgga catgacgacc ttgtgcaccg cgatgccgcg ctcctccacg
     5161 agggggatgt cgaacaccga catcccctgg gcctcggcgt cgatcaacag ctggcggagc
     5221 tcgtgcctct catgcaggcc gagatctgcc acgccgacct ccggcccatc gtgcatgtcg
     5281 gggaacaggc ccggcagcgc gtcgaccgct gaacccgtga accagaggtt gcgcatgtcc
     5341 gtgtccctgg gtgctatcgc gacgcgggcg tcgagcgagt ggagcatcga catgcactcg
     5401 aggaacgcat cacgcacgct cgcggagagg gtcgaggcga aagccgagcc gaacgaggcg
     5461 cgtgcgcggt gcgaggcgcc gcagaccatg gccaccgtga cgaccggggc gtcgaacggg
     5521 ttgtccagca gggtgaccga gaaccgggcg tcgacggcgg acatcgcgtc gcgcacatcc
     5581 tcgggtacga gcgcccatcc gagcggggtg ggcagcgcct ccgtccgtgc gtagtactgg
     5641 aacgcatcgc gctccacgac ctcgcgtagg cccaggtgga aggcctcgac ggcggatgcg
     5701 cgacacgctg caccgcctgc gtcggagggg gcgatctgcg acgcgcgacg aggatcatgg
     5761 cgatggatcg ccagggcagc ggggacgtag acggagcggc cctcgaggat gtcgacggca
     5821 ggcatccact cccgggagag ggccatggaa tggggcatcc cgagcggagc gtcgacatgt
     5881 gcgaggccga acacgcgctc gacatcgacc gccccctcga gctcgagggc ggacgcctcc
     5941 acgacgagcg gatgcgtgcc ctgtcccagg gtgtaccgct cgagcgcggc acccagacag
     6001 ctggcgaggg cctcggcgtc ggtggccccc ttcccgcgcg ccatacccgc caggtcgggg
     6061 tcgaaggcat cgcggatggg cgctgtcgcc agtgatacgc cgcgagaccg acgagctgtc
     6121 gtcgggttgc cggcgatcga cgcgaacccg aacgcccacc tcatgcgcga cacgaaggag
     6181 gcggctcggg aagcgcggtc atcgtccgat gactcaaggc caccggtcgt ctccatagtg
     6241 accatggagg cgaacgtcgg cgggaccacg ggccgcccgc ggccggagca gttcgggcat
     6301 cccgccacgg ggcggatgca ggaccagtcc tggctggcgt aggcatcggt gaccgccatg
     6361 gagaggtcat gcaggttgtg gaacgcctgc acgatctcgc gggctccgga gtcgtggggg
     6421 ccgggagccg ctcctgtccc gtagtggtgc tcgaggaagg cgggaatggt cgataggcag
     6481 cgtgtgcacg catcgcgctc gtcggtccgc agcagcgccc aggtgacgtg gcccgatccg
     6541 aacaggcacg cgcgtgcgtg catctcatcg agggaagctg acgcgacgac gaagatgtgc
     6601 cgttccgcag gcaggagccc gagctcgatg cagatctcga cgtacgcccg gtacgggtct
     6661 ctgggggcca ctgtgtcctc gtgctcgtgt ctgtcatggg tccggatcgt cgggcaccga
     6721 cctctctgac ggatcgatgg ccatccccgg acgagacagc cctcgaccag tgagggctgt
     6781 cggcgctcag ccgcggcgac gtgcagtcgg cgtggctcgt ccctgttccc ggtcccgagc
     6841 gagcaggggg tcggcgatcc gaccacggcc gccgacgggc aacccgttct cgcgcagcca
     6901 ggcgtgcgcg tctgcgcgtt ctcgggtctg gacggtcgtc cgatcggcgt gccgcgatgg
     6961 tctcgacggt gttcggcgag cggcgtccag gtacggctcg aacgcctgtc ggagctctgc
     7021 agcgtgcgtg atgctcagat cgatctcgaa cagcaggccg tcgatgccga accgcacggt
     7081 ctcgccggga ttgaggtcgt ccaacatcga accgtcgatg tcgtcgaagg tgtgggacat
     7141 gtcgttcgtc gccattcagg gctcctggtt cgttgcgtgg ggggccgcgc ggccgcaggg
     7201 cgcgtcctcc atcggcggcg gcgatgcgtc cctgctcgtg cgggcgcgga tccgcatcat
     7261 tgggacatgc gacgccagac cgcttgggcg tccgcgaggt gctggccgtt ctccgggagg
     7321 cgcagccact ccgtgtaggt gtggtccctg cccagacgac accggcacgt gagagccacc
     7381 gcttggccgg tggcggtcgt gtgcgtctcc tggtggcgcc gaccggtgag cgtggtgatc
     7441 gcaccgtccg gggagtcacc tcctgcgagc ggacgaccgt ccggagcctg gacgctccgt
     7501 gcccgccagc gggcggtcat ccgtgcctcg ccctgagcag gaggcagccg acgatgaacg
     7561 acagcgtcga tgctccgagc aggcaggtgc tgcaggcgtc gccgacgtat gccgacacca
     7621 ctgacccgac tcccagagcc aaggagaact gcaggaggac caagcccgcg ttagcgcgca
     7681 tgacggccga cgatggttcg gaatgcgcgg atcacgcgta tgaatctccc gcggaggccc
     7741 ccgtggtcgc gcgcacgata ctgcgtctgc gcatcacgca tgcgccgccg gcgcatgcga
     7801 tccatctctc ggatcgcctc ggggacgaac gcgatgtaga cctcgctggc cccggcgcgg
     7861 cgacggcgat accagtggta ggccttcgtg cggtgccgtt tccggtgggg tgtgcggccg
     7921 atgggcatgc gggtccttct ctcatccgcg cgtcgggtca cgtgatcagc tcgttcccca
     7981 atggggatcg gggcacgaga tgcatgcgac tcggtggtgc gagaagaagg atggcggtgc
     8041 cggaccagga ggagcggagg agcggaatcc ccagcacgcg agcactctac ggccgcgtgg
     8101 cgaggatcag ggaagggagt ccgagaaatc gtcctgcaca tcaccccggg cagcacaaaa
     8161 ctctagatca gtactactga tctagtacga ggtcggtttt ggagtatgac cccgacgtat
     8221 catcgctcct gaccggagca tatgcggaat gtcaccactt tggggggcgt ccgttgggga
     8281 attcgactca ccgcagggtg agatcgacgt gatcaaccgc tcaatccatg cctattcgct
     8341 aggtgaagga acgggcggga tatgtactgg ccgggccacg tcgatgtctc tggggaccgt
     8401 cgacatgtca gccgccaccc acagcagaag gacatctgac atgagatcaa ccggctccac
     8461 cacccaccct cgcagccctc aggggtctaa gcggtggctc cgactggatg cgaccaccaa
     8521 gcagagtcgc ttctccgccg cggtgctcgc catcgctttg atcacctcgt ctctgactct
     8581 gggatcgggc ctgttcgggc cagctccggc ggcacaggct gccgcgggca acccgggtgt
     8641 ccccagcgcc ccgacgaccc tgtacacgga ggacttcgag aacgccgcga cggcgacggc
     8701 catccctttg acgtcgtaca cgggtgcgac cgggacgacg tacaactcgg acggtctcta
     8761 tggggatcaa ggtgagtgca atgggctggt actgaatccc aactcggcgt tcgctggcaa
     8821 ccagtgcgtg aacggcccca acagcgtcaa caacaaagcg accctgaaga acatggtagg
     8881 ggcccttggc gcgctcaatg gcacgggagc ggcgaacgat gctgtctcgg cgatgacagc
     8941 gtcacagaat gtgccgccga acaccgtgga attcaggacc acgaagcaaa tcgccttgcc
     9001 cgccgcgaac ggccgcttca tcacgctggg ggtaagcgtc gccgcggcgt gtggtgacgg
     9061 cggagccgac ttcaaccaac ctcgtctggc cttcaacttc gtagacagcg cgggacgcga
     9121 gacgtccgcg acgaacaatc ctgtcaatcc gtgtggcggg gccacgcagg ggattctcgc
     9181 gaaggcgctc gtgtcggaca agggaattct tttcagcggc tcgtctgtcg gaatcaacat
     9241 gcgaaacgtc gatggcgggg gaaaccgtgg taacgaccat gcattcgacg acatcaagat
     9301 cctcgacgtg acgccgcagc tggacaagtc gttcagcccg gccagcgcga ggacgggggg
     9361 caattcgacg ctcaccttca ccatcaccaa cacgagcgag ctcgggcaga agaacggttg
     9421 gtccttcacc gacgccctct cgtcggggct cacgatcagc aacccttccg ccgcgacaac
     9481 gacctgtgca tcaggcgtag tgaccgcccc ggcgggtggc accagcgtcg ccgtcaccgg
     9541 caacctcaat gcggggcaga cctcctgcac cgtctccgtc aacgtgacct cgaacacggc
     9601 cggcacctac acgaacggcc cgcagaacgt cacgacgacc ggcctcaacc ctcctggcac
     9661 ctccaccgtc acgttcagca acccgagcgt cggcgtcatc aagcgcgccg gcaccccggt
     9721 ggatgtcaac ggcaacggcg tcaccgacgc gggtgacacc atccagtaca ccttcgacgt
     9781 cacgaacacg ggagacgtcc ccctgtcgaa cgtctccgtc acggatgcga aggccggcac
     9841 ggtcacctgc ccctccggga cactcgcccc gcaggcgacg gtgacctgca gcgccgccgc
     9901 gccgtacacg atcacgaccg ccgaccagaa cgcgggcgcg gtgaacaaca cggcgaccgc
     9961 ttcggggacg ccgccgaact ccacgacccc ggtcacctcg acgccgtcca ccacgagcac
    10021 tcccgtgacg actcccgtgc agtccctgac gctggacaag accgcgacgc cttccgacgc
    10081 cgcgtcgttc accgtgggac ggcagatcac ctactcgttc ctggtgacca acacgggcaa
    10141 cgtggcgctg aacgacgtca gcatcgatga gacctccttc accggttctg gcacgctctc
    10201 caacgcgacc tgccccgcga cgaccctcgc ggccggagcc tcgaccacct gcaccgccac
    10261 ctacacggtg acgcaggcgg acgtggatgc cggcggcgtg accaacacgg cggtcgcgaa
    10321 cggcacccct caggggagca ccacgccgat cccgtccaac cccgacaccg tggtgctgcc
    10381 gggcctgagc acgccgtcca tcaccctgca gaagacggcc tcgccgacga cgatcagcgc
    10441 cgcgggcgat gtggtgacct actcgttcgc cgccacgaac aacggcaacg tcacgctgac
    10501 gaacgtcacg atcgatgaga cccagttcag cggcaccggc accgcgccgg tcatcacgtg
    10561 cccgtcgggt gccgcgtcgc tcgctccggg cgcgtcggtc acctgcacgg cgacctacac
    10621 cgccacgcag gcggatgtcg acgccgggca gatcacgaac acggccaccg cgaccggcac
    10681 cccgccgcgc ggcccggccg tcacgtccga cccctcgcag gcagtcgtca cggccgaccc
    10741 gaacccgtcc gtcgcggtcg tgaagtcggc gaacccgagc tcgatcatga acgcgggcga
    10801 gacggtcgac tactcgttcg tcgtcacgaa cacgggcaac gtcacgctga cgaacgcgtc
    10861 cgtgtccgag acccagttca gcggcacggg tacggctcct gtggtgtcct gccctgatgc
    10921 ggccgcgtcg ctcgctccgg gcgcgtctgt gacgtgcacg gcgtcgtatg tggcgacgca
    10981 ggcggatgtg gatgcgggtt cgatcacgaa cacggcgacg gcgacgggga ctcctccgag
    11041 tggtgatccg gtgacgtcgg atccgtcgtc tgctgtggtg accgctggtg cggctccggg
    11101 tctgacgatg gtgaagtcgg ctaacccgac ggcggtgtcg aaggtgggtg acacgatcac
    11161 gtattcgttc ttgttcacga atacgggtaa cacgacgttg acgaacatca cggtgaatga
    11221 gacggcgttc tcgggaacgg gtactccgtc ggctgtggct tatccgacgc gtacgttggc
    11281 gccgggtgag tcgacgacgg cgacggcgac gtatgtggtg acgcaggcgg atgtcgatgc
    11341 gggcaaggtc gataactcgg cgacgggtgc ggggactcct ccgggggata ctccggtggt
    11401 ggtgacgcct ccgtcggatg tgacggtccc gatcgatccg gctccgggtc tgacgatggt
    11461 gaagtccgct aacccgacca cggtgtcgaa ggtgggtgat acgatcacgt attcgttctt
    11521 gttcacgaat acgggtaaca cgacgttgac gaacatcacg gtgaacgaga cggagtt
//
