LOCUS       NZ_JADKRR010000002     24422 bp    DNA     linear   CON 16-AUG-2024
DEFINITION  Clavibacter sp. VKM Ac-2872 n2, whole genome shotgun sequence.
ACCESSION   NZ_JADKRR010000002
VERSION     NZ_JADKRR010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Clavibacter sp. VKM Ac-2872
  ORGANISM  Clavibacter sp. VKM Ac-2872
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1  (bases 1 to 503716)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Draft genome sequences of plant-associated actinobacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 503716)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2020) All-Russian Collection of Microorganisms,
            G.K. Skryabin Institute of Biochemistry and Physiology of
            Microorganisms, PSCBR RAS, pr. Nauki, 5, Pushchino, Moscow Region
            142290, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 675x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015351105.1-RS_2024_08_16
            Annotation Date                   :: 08/16/2024 04:34:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,385
            CDSs (total)                      :: 3,333
            Genes (coding)                    :: 3,309
            CDSs (with protein)               :: 3,309
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 2 of 24
            Pseudo Genes (incomplete)         :: 19 of 24
            Pseudo Genes (internal stop)      :: 4 of 24
            Pseudo Genes (multiple problems)  :: 1 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:57:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 338594
            Orig. end                         :: 363016
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADKRR010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24422
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24422
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24422
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14422](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14422)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1960..1976)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            2035..3462
                     /locus_tag="ITJ40_RS12010"
                     /old_locus_tag="ITJ40_12010"
     CDS             2035..3462
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019181061.1"
                     /locus_tag="ITJ40_RS12010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12010"
                     /product="CitMHS family transporter"
                     /protein_id="WP_228512419.1"
                     /transl_table=11
                     /translation="MVLTFMALIMTKRLTPMVALILVPTIFGLFAGAGLGIGDMVIEAL
                     GDLAPTAALLMFAIIYFGIMIDVGLFDPLVRLILRLAGGDPAKIVLGTAILAAAVSLDG
                     DGSTTFIVTTAAMLPIYRKLGMSPVVLTCTAGLANGTLNIVPWGGPTVRAAAALKVSPT
                     DIFVPMIPSLLVGIALVMIFAWTMGLRERSRLAALGEARAEGGLDAAGGTGSGSGGSTG
                     GSGWWRAGRGAPATPRGGLITMAPALVRAETAAVSTLGTTMLDPDRETLRPRMIWFNLG
                     LTIVVLALLIMDQLPLAYVFMVGAAIALIANFRDLKHQGERIAAHAPSVVGVVSMVLAA
                     GVLIGVLNGTGMVSAMSAWLVTIIPDALGPGLAVITGVLSIPMTFFMSNDAFYYGMLPV
                     LAESAANYGIDPVEMARASITGQPVHLQSPLVPAILLLVSLTDVNLGDHHRKVLWRAVL
                     VSLTMLAVGVLTGVIPI"
     gene            complement(3490..4959)
                     /locus_tag="ITJ40_RS12015"
                     /old_locus_tag="ITJ40_12015"
     CDS             complement(3490..4959)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039567.1"
                     /locus_tag="ITJ40_RS12015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12015"
                     /product="DUF2079 domain-containing protein"
                     /protein_id="WP_194667285.1"
                     /transl_table=11
                     /translation="MTRTNDTAHRRHADDDGSVEPDPTIALRAPITGSRVPGTVGVVVV
                     AALVTAVYVLYSALEWRRFTVKSWDLGIFTQLAQDYSRLQAPLVSIKGDGFNLMGDHFH
                     PILVLLGPVYAVWPHAFALLVVQAVLIGISVVGIGRLAGRVAGRWGAIVVAAAYGLSWG
                     IQGAVAFQFHEIAFALPLLAFALDAVIARRALAAAAWAVPLVFVKEDLGLTVAVLGVII
                     ALAMDRRIGVALAGWGVAWFVLATTVILPAFNREARWDYASKLDAGGALADPFGTIAGL
                     FVAPKLETVAFLVLAGAFIALRSPLILLVVPTLAWRFLSPTEAYWGPGYHYDAVLMPIV
                     FAAAIDGIVRARAGRQHWIAVASRATVPVLAIVAVALFFRSPMAELTKPTIWQAAPRAA
                     QAQAALDQVPAGASVLSDIGLMSYLVDDHEVYWLGNPGNPAPQYVVIDTLGGGLGQGAL
                     NADQYGEATQAGATYEIVYADAGYQVARRTQ"
     misc_feature    complement(5021..5035)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            complement(5060..5491)
                     /locus_tag="ITJ40_RS12020"
                     /old_locus_tag="ITJ40_12020"
     CDS             complement(5060..5491)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039568.1"
                     /locus_tag="ITJ40_RS12020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12020"
                     /product="DUF5997 family protein"
                     /protein_id="WP_194667286.1"
                     /transl_table=11
                     /translation="MTSPGSSQTMKAATAAKKLGVHLPATPVEFQESTPSRAELAEMHA
                     NPPEWLATLLRDGPHPRPVIAGKLGISIAGLARGGVDEALTTAQIKELLQAPPQWLVQE
                     RATQAEVREEQIRVKNRDAGRAAMAAERERQDGAGGARR"
     gene            5595..6620
                     /locus_tag="ITJ40_RS12025"
                     /old_locus_tag="ITJ40_12025"
     CDS             5595..6620
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039569.1"
                     /locus_tag="ITJ40_RS12025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12025"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_194667287.1"
                     /transl_table=11
                     /translation="MDADPTALRHFAAVADELHFARAAKALNVSRIAVSRSILDLEALW
                     GVELFVRDDGPTRLSPAGEERLVEARAAIAAEDARRAAEAAAPPRGLVVAIVPGVTVAK
                     WTRAWDERVADVPLRVVPLAEPAAAPALVDGSADVAFLRLPVDGRGLTIVPIYGEVQVA
                     ILPKEHAHATADAVAIAELADELLLQPADQVPGWAGRTAGADPVPMPDDVAAAVELVAA
                     GVGFVVVPHALGRLHARKDVVAVPVHDLPETRIAVAWREGDASPEIEELVGIVRGRTAA
                     SSRSQRDDDERDRRKPTAAQKTARKAAGKPGAAGGKGGSKPTPKGGGKRTPPPRGQRRG
                     R"
     gene            complement(6651..7382)
                     /locus_tag="ITJ40_RS12030"
                     /old_locus_tag="ITJ40_12030"
     CDS             complement(6651..7382)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491440.1"
                     /locus_tag="ITJ40_RS12030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12030"
                     /product="hypothetical protein"
                     /protein_id="WP_194667288.1"
                     /transl_table=11
                     /translation="MSSPIRLLHQTVRPFVAASLRGGIPTPLTATVPTDAPVGVVAGPD
                     PDRVLALGGIGGSGVGLRTHAEGVAAQSARALAAITGRGVEWRTVPLADQHLTATQEAV
                     RQITELHRYDVVLVMPGVADALELARITPWVHRLEDLLDHLVEQTADNSIVLVSDVPQV
                     SQYVEAGTFVRGLFRDHAMYLSQRKAEVCARFPQVTSVKLPDAGPVDFEDGEFRYASMY
                     RRWGAHVGRVVADLQAGRRPA"
     gene            7521..7844
                     /locus_tag="ITJ40_RS12035"
                     /old_locus_tag="ITJ40_12035"
     CDS             7521..7844
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491441.1"
                     /locus_tag="ITJ40_RS12035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12035"
                     /product="hypothetical protein"
                     /protein_id="WP_194667289.1"
                     /transl_table=11
                     /translation="MIREPEPLVPHPPHARFHQGAWRVQVASQPVLGYVVPTARTAGAD
                     PVFEVYADAVDDSGRRVWVSTAVTLEDAVAWMREHDMELLSFAGEHARRRRELATGMMP
                     THY"
     gene            complement(7838..9091)
                     /locus_tag="ITJ40_RS12040"
                     /old_locus_tag="ITJ40_12040"
     CDS             complement(7838..9091)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="ITJ40_RS12040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12040"
                     /product="MFS transporter"
                     /protein_id="WP_194667290.1"
                     /transl_table=11
                     /translation="MDEAADDDVTDVRPGRVVTWRRLPVEVRILVLARAVNRLGAFTLP
                     FLTVVLTVDLGASLATAGLVVALFGAATIPSRILGGLLADALGRRSTIALGLTLTAAFQ
                     LMLAAAPGIATAAVAAVLLGLAFEVYEPASQALIADLVTDDRDRVAAYGLYGAALAVAG
                     VAAGVLAAILGGIDLRLLFVADAVSCLACAALVLVGLRRGSPVAAEEPAGDAPAPVAGA
                     RSPWRDPLLLVMLATGTGFAVLYLQIDVALPLTLAERGIDPASLGILLAVSALTIVLGQ
                     PLLARGPASRLGSTAGMAVGFVLLGLGFALVGQAAGLPGLVAATVVWSLGDLILLGRAT
                     ALVAAIAPAAARGRYLSAYGISWGVAAMVGPLLGTQLIAHLHAAGTWDVLGALCLALAL
                     AQPLVAAVARRSGRLLAQ"
     gene            complement(9112..10008)
                     /locus_tag="ITJ40_RS12045"
                     /old_locus_tag="ITJ40_12045"
     CDS             complement(9112..10008)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491442.1"
                     /locus_tag="ITJ40_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12045"
                     /product="prenyltransferase"
                     /protein_id="WP_194667291.1"
                     /sec_met_domain="ubiA (E-value: 2.3e-15, bitscore: 51.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVRARPGAAETLRTIALSSRPLSWVNTAFPFAAAYLTVTRDLD
                     LTAILGTLYFLIPYNLAMYGINDVFDYESDMRNPRKGGVEGAVLARAMHRPVLIAVLVT
                     NVPFLVYLVAVGSAASVAVLAVSVFAVIAYSLKGLRFKERPVLDSLTSSTHFTSPAVYG
                     IVLAGGAFTPALWAILAAFFLWGVASHAFGAVQDIVADREGGISSIATVLGGAVTVRIA
                     VLAYAAAGVAMLFTGLPGIIASVLVIPYILSTAPFWSIRDEDAGAANRGWRRFLGLNFL
                     SGFVVTMLLIAYWLTNA"
     gene            complement(10001..10369)
                     /locus_tag="ITJ40_RS12050"
                     /old_locus_tag="ITJ40_12050"
     CDS             complement(10001..10369)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039573.1"
                     /locus_tag="ITJ40_RS12050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12050"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_194667292.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 4.5e-14,
                     bitscore: 47.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYLALDLLFLLPVAVVGFLFRRLLLREANAVPYGSSRFDYPEYY
                     WYRRMPVLILLVMTLIFDNIMIKVGLVGYDDDKLVGLILGYAPVEDFAYAIAALVLLPA
                     VWYLLRRRRSVSGIEAHE"
     gene            complement(10366..10710)
                     /locus_tag="ITJ40_RS12055"
                     /old_locus_tag="ITJ40_12055"
     CDS             complement(10366..10710)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039574.1"
                     /locus_tag="ITJ40_RS12055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12055"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_194667293.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 8.7e-18,
                     bitscore: 59.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLVYLVLLLGALGCMMLIDRRWRLFFWRDRTAAILTTLIGVAFF
                     LAWDIAGISQGIFFRGETAFMTGILVGPELPLEEVFFLALLCYLTMNLVNGFSRLADHH
                     VARARERANR"
     gene            complement(10710..13355)
                     /gene="crtI"
                     /locus_tag="ITJ40_RS12060"
                     /old_locus_tag="ITJ40_12060"
     CDS             complement(10710..13355)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491445.1"
                     /locus_tag="ITJ40_RS12060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12060"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_194667294.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.1e-29,
                     bitscore: 96.7, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 7e-32, bitscore:
                     105.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1.3e-15, bitscore: 52.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRLPGRRPAAPEEPTGLEKYDRVAQETASVVIRRYSTSFGLAS
                     RLLGPDVRQHIENVYALVRVADEIVDGAAAGAGVDPAHVEELLDALEQETEDAMLRGYS
                     TNLVVHAFAITARRAGFGAELTAPFFASMRMDLRRMEHTPASFTEYVYGSAEVVGLMCL
                     RAFLVGHATTRPERIRFEEGAKRLGAAFQKVNFLRDLAADHGALGRSYFPGVDVASFSE
                     ADKERILDDIDHDLRVSGAVIPDLPASSRRAVALAQGLFAELAVRLRDTPASELVRTRV
                     RVPDPVKARIALAAASGAEPSGVDGRLVRRSRGPRAHAARPAPASRPAPTEPAPSDPAP
                     SDPEQQESAMTAPTAIVIGGGIAGLASAALLARDGYRVTLVEGRDEVGGRAGSWEKDGF
                     RFDLGPSWYLMPEVFDHFFRLLGTSAADELDLVRLPGYRVLFEGESDPIDIRDSREANL
                     DLFESVEPGSRPAMARYLDSAKDVYEVAKKRFLYTTFADYRSLLKRDVVTRTGTLGKLL
                     LTPLETHVARYVKDRRLRQILGYPAVFLGSSPKLAPSMYHLMSHLDLEDGVLYPQGGLI
                     TVIDAIERVARAEGVEIRTGAPVSRILTEPTKAGKARARGVQITTDAGTETLDADVVVS
                     TADLHHTETELIPEAFRTYPQAYWDKATAGPGAVLVYLGVEGELPELHHHTLLFTEDWD
                     ENFSRIFPPKGGTTSVPDPASLYVCKPSATDASVAPAGHENVFILVPIPADPTIGRGGI
                     DGAGDARVEEIADRAIQQISDWAGIPDLAERIVLRRTSGPGDFAADLHSWKGTILGPAH
                     TLTQSAMFRAGNTSKKVDGLHYAGGSTIPGIGLPMCLISAEILVKRLRGDTSTGPGAVP
                     LVRTVGRPVV"
     gene            complement(13352..14422)
                     /locus_tag="ITJ40_RS12065"
                     /old_locus_tag="ITJ40_12065"
     CDS             complement(13352..14422)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491446.1"
                     /locus_tag="ITJ40_RS12065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12065"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_370532045.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.1e-48, bitscore:
                     159.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDATNLAAVSTTRQAHVNGVLDAFFARSLVRAEVMGPEYVKLWRT
                     LESNTAGGKRFRPRMVMAAYDGLGGQDVQAAAHVGAAFEMLHTALIVHDDVIDRDFTRR
                     GGPNVSGAYRDIATTQGLPQPLAEHRGMSAAVIAGDLALVNAYRLIDASGVRDLTRSHL
                     LELLDDAVFASAAGELIDVEFSLTADVPSVDEILRMERLKTAVYSFEAPLQAGAVLAGA
                     RPEVVAALGDFGRDIGIAYQVVDDVLGVFGDEQETGKTNLGDLREGKRTVLIAHAVRSS
                     EWGEISALVGKDDLSRGEAALVRSVLESSGARTYAEGVARDLAVAAVARLDDPVVPEAL
                     RRELAPVAESVLGRIR"
     gene            14467..15051
                     /gene="idi"
                     /locus_tag="ITJ40_RS12070"
                     /old_locus_tag="ITJ40_12070"
     CDS             14467..15051
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012299869.1"
                     /locus_tag="ITJ40_RS12070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12070"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_194667295.1"
                     /transl_table=11
                     /translation="MSQHTELVVLLDDDGEPIGTAPKATVHTRDTALHLAFSCHVFDRQ
                     GRILVTRRAIGKLTWPGVWTNSFCGHPAPDEDMLEAVHRRAEQELGLELASVELVLPDF
                     RYRATDAAGVVENEICPVFRAIAATPVDPRPEEVGEYQWVDPEELIPAVAHTPWAFSPW
                     LTLQLPLLYPEHAAHAGLADAEADADAVPAA"
     gene            15138..15893
                     /locus_tag="ITJ40_RS12075"
                     /old_locus_tag="ITJ40_12075"
     CDS             15138..15893
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="ITJ40_RS12075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12075"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_194667296.1"
                     /transl_table=11
                     /translation="MESESARVTRIRPFYASQVDAYDAIVSAPVEGWIEEIRGHRTDGG
                     LLDAGCGTGRHAEALARAGFEVELADASPAILAVARTRNPGIRAHLADICTVDLGRRYD
                     VVACRGVLNDMLSDVERSAAVERLAAHAAPGGVLVLDVRDRDATRDRAGRTTTTEGALP
                     DGRTVRFRSSTTWADPLVRVRELHEIIAPGRPTESEPFDFAMRPWTRRELTDALGAAGL
                     VDVVVDAAAHRPSGDRLVASGRRPLSFAG"
     gene            complement(15942..16820)
                     /locus_tag="ITJ40_RS12080"
                     /old_locus_tag="ITJ40_12080"
     CDS             complement(15942..16820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012300141.1"
                     /locus_tag="ITJ40_RS12080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12080"
                     /product="patatin-like phospholipase family protein"
                     /protein_id="WP_194667297.1"
                     /transl_table=11
                     /translation="MTGTERDTTTPTRGLVLGGGGVAGIAWETGLLSGLLAAGVDLGAA
                     DAVVGTSAGSVVAINLRAGAIDAAYDEHFVDVAGMAEPMGSRDLSRTIEVIGEGIVSTA
                     GEIPTRQKIGEFALEEYDPEVDDAASVERIGQLLPIRDWPEADLRITAVDAGTGRFTVF
                     DKASGADLVRASAASCAVPGVFPPVTIDGRPYMDGGMRSGTNADVVAEHERILVIACGP
                     EAPQSGMGPTLSTVVQQLRGRADVLVIQADDDSTAAFGENSLLLSTRKASAEAGRRQAE
                     RVADEIRAFWG"
     misc_feature    complement(16870..16883)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.03"
                     /tool="antismash"
     gene            complement(16948..17532)
                     /locus_tag="ITJ40_RS12085"
                     /old_locus_tag="ITJ40_12085"
     CDS             complement(16948..17532)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039579.1"
                     /locus_tag="ITJ40_RS12085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12085"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_194667298.1"
                     /transl_table=11
                     /translation="MSRARPRPDPDAPAAPTAAAAALPAPGAGVPADAGAAGELGRILR
                     NVLGLAAGFERRLGGVLEVNPTDMKAMEHLIQEGSLSPTELAGRLGVSTAAATLVVDRL
                     VEVGHVDRRPHPHDRRRVVVVPRPASVGQAMAELMPMIGGVARAADALTDAERAAVTRF
                     LGEVREVYREAAAGPAGPAASASAADPSAAR"
     gene            17610..19685
                     /locus_tag="ITJ40_RS12090"
                     /old_locus_tag="ITJ40_12090"
     CDS             17610..19685
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039580.1"
                     /locus_tag="ITJ40_RS12090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12090"
                     /product="MMPL family transporter"
                     /protein_id="WP_194667299.1"
                     /transl_table=11
                     /translation="MRSIARFVSARRTAWMALVIAVAAVAALFAFLPKGEADAFPPSGL
                     PDSSQAKQVSELLERFPSADTTVGILVFSRDGAALTDADTAAIAQRAEALAADSIAPQA
                     VVPQASDDGRAALVAVPLDASAVADDVAGTAATLRTTASDGLPDGLVAQLTGPVGFQAD
                     ISNAFAGADFRLLLVTVLVVAVLLIVTYRSPVLWIVPLVVVGAADGLARVVVTALADPL
                     GITIDASIGGILSVLVFGAGTNYALLLVARYREELTRQEDRHAAMLTAVTSAGPAIAAS
                     GGTVALSLITLLLAELSGNRALGFACAIGVLIAIAAALLVLPAALVVCGRGLFWPFIPR
                     AGTDADHGGKPGVWRRLGLGVRRRPAVVAVVALAGVGVLALGLVGARVGLSQTDQLLGD
                     PESVAAQEVVDASFSAGLTAQTVVLAPDAVADDAVATAESVPGVAGARAGESAEGRTRI
                     DVQLDAEPESAAAFAAVQDLRDAYAAAPGEQSTTLVGGSDATAADTAASSERDQGLIIP
                     IILAIVFVILGLLLRSLMAPVLLIASVLATFFASLGAANVLFQQVLGFPAFDANVVLFA
                     FLFLVALGVDYNIFLVTRAREERRLHGTREGMVRALASTGGVITSAGILLAAVFAVLGV
                     LPVVALTQIGVIVCIGVLLDTLVVRTLLVPALVFLLGDRFWWPSHRGARHRETVDA"
     gene            19682..20164
                     /locus_tag="ITJ40_RS12095"
                     /old_locus_tag="ITJ40_12095"
     CDS             19682..20164
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039583.1"
                     /locus_tag="ITJ40_RS12095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12095"
                     /product="DIP1984 family protein"
                     /protein_id="WP_194667300.1"
                     /transl_table=11
                     /translation="MRLAEALMERSDLQRRIESLRNRIQASARYQEGEDPAEDAAALLA
                     EAGEAVDLLAALVTRINLTNTAARLDDGTPLTSALARRDALRTRHGILTAAADAASGRV
                     AAGVYAQRQLRSELRLIAALPIREVRDRADDAAKELRELDARIQRANWEVELVEEA"
     gene            complement(20446..21141)
                     /locus_tag="ITJ40_RS12100"
                     /old_locus_tag="ITJ40_12100"
     CDS             complement(20446..21141)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039585.1"
                     /locus_tag="ITJ40_RS12100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12100"
                     /product="hypothetical protein"
                     /protein_id="WP_194667301.1"
                     /transl_table=11
                     /translation="MTFSYAPEPDTSAPRERKTFNGVGLAALIVGVLSLIGSVIPILNY
                     VSGFLAAIGIVLGIIGLILKDRPKGMALGGLIASIVALILSIVLAIVYTAGIVTAITGA
                     VRESEARSSAEASDEPRVTYQVEGSGGTVTAGVLWTTSVGGTAGSEQASDQPLPFSREV
                     VIPDTTDFDMAAFSVSAVASVDPTVSADGDITCRILVGDHIVTEQRAEGDGATVTCTAT
                     AEDLRDLAD"
     gene            complement(21215..22333)
                     /gene="ald"
                     /locus_tag="ITJ40_RS12105"
                     /old_locus_tag="ITJ40_12105"
     CDS             complement(21215..22333)
                     /EC_number="1.4.1.1"
                     /GO_function="GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ald"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012300146.1"
                     /locus_tag="ITJ40_RS12105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12105"
                     /product="alanine dehydrogenase"
                     /protein_id="WP_194667302.1"
                     /transl_table=11
                     /translation="MKVGIPTEIKNNENRVAATPAGVHELVRRGHEVLVQEGAGLGSSI
                     TDADYVEAGATIVATADEVWGAADLLLKVKEPILEEYPRMRPGQTLFTYLHLAASRPCT
                     DALVASGTTAIAYETVQLPNRQLPLLQPMSEVAGRLSTQVGAYHLMRAAGGRGILLGGV
                     PGTPKARVVVIGGGVAGEHAAANALGMGADVTIIDLSIPRLRELENRFGGQVQTRVSSA
                     YEIAAQLKDADLVIGSVLIPGAQAPKLVTDAMVATMKKGSVLVDIAIDQGGCFEGSRPT
                     THDDPTFDVHDSVYYCVANMPGAVPETSTRALTNATLPYVIALAEKGWKRALAEDPALA
                     LGLNVHDGHVTNSHVAAALEMPLTPVADVLAA"
     gene            22500..22994
                     /locus_tag="ITJ40_RS12110"
                     /old_locus_tag="ITJ40_12110"
     CDS             22500..22994
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039587.1"
                     /locus_tag="ITJ40_RS12110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12110"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_194667303.1"
                     /transl_table=11
                     /translation="MPTKEMRTPEPLDAVDRKLVALLRADARTPNSRLAEQAGIAPSTC
                     VTRVRGLVERGVITGFTATIDADAVGVGLQALISIAIRAGARHEMAAFASEMRELADVV
                     QLFFLGGSEDFIVHIAVRDSDHLRDFVLKHLSAHPAVASTRTSVVFDHHYSGPAVGDPG
                     A"
     gene            complement(23011..23616)
                     /gene="dcd"
                     /locus_tag="ITJ40_RS12115"
                     /old_locus_tag="ITJ40_12115"
     CDS             complement(23011..23616)
                     /EC_number="3.5.4.13"
                     /GO_function="GO:0008829 - dCTP deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006229 - dUTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Deoxycytidine deaminase"
                     /gene="dcd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039588.1"
                     /locus_tag="ITJ40_RS12115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_12115"
                     /product="dCTP deaminase"
                     /protein_id="WP_015491456.1"
                     /transl_table=11
                     /translation="MLLSDRDITAELDAGRVALDPYDPGMLQPASIDVRIDRFFRLFDN
                     HKYPYIDPAEDQPELTRLIESKPGEPFILHPGEFVLGSTFELVTLPDDVAARLEGKSSL
                     GRLGLLTHSTAGFIDPGFSGHVTLELSNVATLPIKLWPGMKIGQLCFFRLSSPAEKPYG
                     SGEYASRYQGQRGPTASRSYLNFVHTDVTVTDAGQPGE"
     misc_feature    complement(23668..23683)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.24"
                     /tool="antismash"
     tRNA            23699..23772
                     /anticodon=(pos:362325..362327,aa:Gly,seq:ccc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="ITJ40_RS12120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="ITJ40_12120"
                     /product="tRNA-Gly"
     gene            23699..23772
                     /locus_tag="ITJ40_RS12120"
                     /old_locus_tag="ITJ40_12120"
     misc_feature    23766..23780
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    24202..24217
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    24328..24343
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    complement(24360..24374)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.58"
                     /tool="antismash"
     misc_feature    24395..24408
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.87"
                     /tool="antismash"
ORIGIN
        1 ggctccgtcg aggtcggggt cgaggtcggg ggcgtggggg tcgtgggggt cgtgatcgtc
       61 ggtggtcggg ccgtccgccg gccgatccgc gtcgggcggc tccaccacgc ccgcgagccg
      121 cgcgcagaac acggcgccgg actccgcgtg gggcggcggg ccgccgggat ccgcgaccca
      181 gacgtcgccg ccgtcgcgcc gggcgatgtc gcgcacgagc ggcaggccga agccgagccc
      241 gtgcgcggga tccggtcccc cggccgccgc gagcgcctcc gcggccccgt ccacgtcgtc
      301 gggccggcgc cggaagatcc ccgcggcgtc cgccgacccg agcccgtcgc ccgagtcggc
      361 gaccgcgagg tgcaggtcga cgccgtcgtc gagcgcctcc acctccaccc acctgtcggc
      421 gcgggatccg tggacggccg cgtgcagcgc gttgtcgacg aggttgccga ggacggtcgt
      481 gacctcctcg ggccgcacga ggatcccgcg cacgagcgtg ccgggcccga cccgcagggt
      541 cacgccccgc tcctcggcct ccatggcctt cgcgccgagg aacgcctgca ggtagggctc
      601 gtcgacgaga cccgcgtcca ccgtggggaa cgccacgggc ccctgctcga gcacgcccgc
      661 gaggtagccg tcggcctcct ccacccggcc ggtcgcgacc aggccgcgca cgacgtggag
      721 gcgattcgcg aactcgtgcc gctgcacgcg gagcgccgtg gacatcgcgg tgacggcggt
      781 gaggcggcga ctcatcgcct cgacgtccgt ctcgtcgcgc agcaccatca ccgtgccgag
      841 gtcgcggccg tcgcggtcga cgcgcgcgac gtcgacgaag aggagccggt cgtcgaccac
      901 cgcgcgcagc gacgcggatc cggcgacggg tgccccgggg gatccggacg cggtccccgc
      961 accggcccgc gccgcggcga ccgcgtcgcg cagcaccggc gcgacgccga ggtcggcgag
     1021 cgtgcggccg accggatcca cgaggccgag cagcgcggcg gcccgcgggt tgcagacggt
     1081 gacgcgtccg tcggggccga gtccgagcac gccctcgccg acgccggaga gcacggccgc
     1141 ctggtcctgc acgaggccgg cgagctcgga cggctggagg ccgagggtga ggcgcgcgag
     1201 ccgccgggag aggatcccgc tggccaccgc cccgactccg agcgcgagca gcgcgacgac
     1261 cgcgatggcc gcgacgtcga cgccgatgga gtcgcgcacg gtcgccgccg cgaagccgac
     1321 gctgacctcg ccgaccacgc gctcgtcggc ctcggccgcg gaggcgccct caggagcgtc
     1381 cgccgtcgcc agcgcccgca ccggcacctt cgcccgcgcc gactccccga gcgtgccggt
     1441 gtcccaggtc acctcctcgc gccccgcgag cgcgaccgtc gggtccgtgc tcacgcgctg
     1501 cccgagctcg gaggcgtcgg gatgggcgag ccgcagcccg cgatcgtcgg tgaccacgac
     1561 gaagagcgcg ccggtgcgct cccgcaccgc ctcggccgtg cgctgcacgg gaccgtcggc
     1621 gaggtcggcc gcgtccgccg ccgcgggatc cgcggtctcg gccgtcacgg cggcccgcag
     1681 cgcgggatcc tcggcggccg tccgcgcgat cgccagcgcc gtcgcctgcg cctcctcgcg
     1741 gttctccgac gagctgagca ggccgtacgc cacggtcgcg atccccacca ccacgagcac
     1801 gacgagcagc tggaggacca gtgtgcggcg cgcgaagtcg agccccgccc gtcgtcgccc
     1861 cgtcgctcga tccacctggt gagcataatg cgcagaacct cgtatacgtg cactatcgcg
     1921 atcaagcggc acaagcgcga cgggacgcgg acgccgacct agcgtgtggt gttcagccgg
     1981 gcgtcccgcc caccgacgaa ggagtcacgc gtgctggtat tcctgggctt cgccatggtc
     2041 ctcaccttca tggccctcat catgaccaag cggctgacgc ccatggtcgc cctcatcctc
     2101 gtgccgacga tcttcgggct cttcgcgggc gcggggctcg gcatcggcga catggtcatc
     2161 gaggcgctcg gcgacctggc ccccacggcc gcgctgctga tgttcgccat catctacttc
     2221 ggcatcatga tcgacgtcgg cctgttcgac ccgctggtgc gcctcatcct ccgcctcgcg
     2281 ggcggcgacc cggcgaagat cgtgctcggc acggcgatcc tcgcggccgc ggtctccctc
     2341 gacggcgacg gatccacgac cttcatcgtc accacggcgg ccatgctgcc catctaccgc
     2401 aagctcggga tgagcccggt ggtgctcacc tgcacggccg gcctcgcgaa cggcacgctc
     2461 aacatcgtcc cgtggggcgg cccgaccgtc cgcgcggcgg cggccctcaa ggtctcgccg
     2521 accgacatct tcgtgccgat gatcccgtcg ctcctggtgg gcatcgcgct cgtcatgatc
     2581 ttcgcctgga ccatgggcct ccgcgagcgc agccgcctgg ccgcgctcgg cgaggcgcgc
     2641 gccgagggcg ggctcgacgc cgccggcggc acgggttccg gctccggcgg atccacgggc
     2701 ggctcgggtt ggtggcgcgc cggtcgcggc gcccccgcga ccccgcgcgg cggcctcatc
     2761 accatggccc cggcgctcgt ccgcgccgag acggccgccg tctccacgct cggcacgacg
     2821 atgctcgacc ccgaccgcga gaccctgcgc ccgcgcatga tctggttcaa cctgggcctc
     2881 acgatcgtgg tgctggcgct gctgatcatg gaccagctgc ccctcgccta cgtcttcatg
     2941 gtcggcgcgg ccatcgcgct catcgccaac ttccgcgacc tcaagcacca gggcgagcgc
     3001 atcgcggcgc acgcgcccag cgtggtcggc gtggtctcga tggtgctcgc ggcgggcgtc
     3061 ctcatcggcg tgctcaacgg cacgggcatg gtgtcggcga tgtcggcctg gctcgtcacg
     3121 atcatcccgg acgccctcgg ccccggcctc gcggtcatca ccggcgtgct cagcatcccg
     3181 atgaccttct tcatgagcaa cgacgccttc tactacggca tgctcccggt gctcgcggag
     3241 agcgcggcga actacggcat cgaccccgtc gagatggcgc gcgcctccat caccgggcag
     3301 ccggtgcacc tgcagagccc gctcgtgccg gcgatcctgc tgctcgtgtc gctcacggac
     3361 gtcaacctcg gcgaccacca ccgcaaggtg ctgtggcggg cggtgctcgt gtcgctcacg
     3421 atgctcgcgg tgggcgtgct cacgggggtg atcccgatct gatcgggagc gctgcgcgag
     3481 gggcgcgtcc tactgggtgc gccgcgccac ctggtacccg gcgtcggcgt agacgatctc
     3541 gtaggtcgcg cccgcctgcg tcgcctcgcc gtactggtcg gcgttgaggg cgccctggcc
     3601 gaggccgccg ccgagggtgt cgatcacgac gtactgcggc gcgggattgc ccgggttgcc
     3661 gagccagtag acctcgtggt cgtcgacgag gtacgacatg aggccgatgt cgctgaggac
     3721 gctcgcgccc gccggcacct ggtcgagcgc ggcctgcgcc tgcgcggccc ggggcgccgc
     3781 ctgccagatg gtcggcttcg tgagctcggc catgggcgag cggaagaaca gggctacggc
     3841 gacgatggcg agcaccggca cggtcgcgcg cgaggccacg gcgatccagt gctgccggcc
     3901 cgcgcgagcg cgcacgatgc cgtcgatcgc ggcggcgaac acgatgggca tgagcacggc
     3961 gtcgtagtgg tagccgggcc cccagtacgc ctcggtcggc gagaggaagc gccaggcgag
     4021 cgtcggcacc acgaggagga tcagcggcga ccgcagcgcg atgaacgcgc ccgcgaggac
     4081 gaggaaggcg accgtctcca gcttcggcgc cacgaagagc cccgcgatgg tgccgaacgg
     4141 atctgcgagc gcgccgcccg cgtcgagctt ggacgcgtag tcccagcggg cctcgcggtt
     4201 gaaggccggc aggatcacgg tggtcgcgag cacgaaccac gcgacgcccc agccggcgag
     4261 cgcgacgccg atgcggcggt ccatcgcgag cgcgatgatc acgccgagca ccgcgaccgt
     4321 gaggccgagg tcctccttca cgaacacgag cggcacggcc cacgcggcgg cggcgagcgc
     4381 gcggcgggcg atcacggcgt cgagcgcgaa ggccagcagc ggcagggcga acgcgatctc
     4441 gtggaactgg aacgcgaccg cgccctggat cccccagctc agcccgtacg ccgccgcgac
     4501 gacgatcgcg ccccaccggc ccgcgacccg gccggccagg cggccgatgc cgaccaccga
     4561 gatcccgatg aggacggcct ggaccacgag cagcgcgaac gcgtgcggcc agacggcgta
     4621 gaccgggccg agcagcacga ggatcgggtg gaagtggtcg cccatgaggt tgaagccgtc
     4681 gcccttgatg gagacgagcg gcgcctggag gcgcgagtag tcctgcgcca gctgcgtgaa
     4741 gatgccgagg tcccacgact tgacggtgaa gcggcgccac tcgagcgccg agtagagcac
     4801 gtagacggcg gtgacgagcg cggcgacgac gacgacgccg acggtgccgg gcacgcggga
     4861 tccggtgatg ggcgcgcgga gggcgatcgt gggatccggc tcgacggagc cgtcgtcgtc
     4921 ggcgtggcgg cggtgggccg tgtcgttcgt gcgggtcacg gcatcagggt ctcacgcggg
     4981 gccgggttcg agggggcgcg atccccggga tcatccgctc agggccggtc gacccggacg
     5041 cgcgtgggtg cgggtcgact cagcggcgcg cgccgcctgc accgtcctgg cgctcgcgct
     5101 cggcggccat ggcggcgcgg ccggcgtcgc ggttcttcac gcggatctgc tcctcgcgca
     5161 cctcggcctg cgtcgcgcgc tcctgcacga gccactgcgg cggggcctgc agcagctcct
     5221 tgatctgggc ggtggtgagc gcctcgtcga cgccgccgcg ggcgaggccg gcgatggaga
     5281 tcccgagctt gccggcgatg accgggcgcg ggtgcgggcc gtcgcgcagc agggtggcga
     5341 gccactcggg cgggttcgcg tgcatctcgg cgagctccgc gcgggacggg gtcgactcct
     5401 ggaactccac gggggtcgcc ggcaggtgca cgcccagctt cttcgccgcg gtcgcggcct
     5461 tcatcgtctg gctggatccg gggctcgtca tgagcccagg gtaccgtcgg ggccccggcc
     5521 gccctgcact agcctggatc ggacccgccg ccgctccgcg cgccaccatc gagcgggcca
     5581 tcgaggggac ccccgtggac gccgatccga ccgccctccg gcacttcgcc gccgtggccg
     5641 acgagctgca cttcgcccgc gccgcgaagg ccctcaacgt ctcgcgcatc gccgtgagcc
     5701 gctcgatcct cgacctcgag gcgctgtggg gcgtcgagct gttcgtgcgc gacgacggcc
     5761 ccacgcgcct cagccccgcg ggcgaggagc ggctcgtcga ggcccgcgcc gcgatcgccg
     5821 ccgaggacgc gcgccgcgcc gcggaggccg ccgcgccgcc gcggggcctg gtcgtcgcga
     5881 tcgtcccggg cgtcaccgtc gccaagtgga cccgcgcctg ggacgagcgc gtcgccgacg
     5941 tgccgctgcg ggtcgtgccg ctcgccgagc ccgccgcggc gcccgccctc gtcgacggat
     6001 ccgcggacgt cgcgttcctc cgcctccccg tggacggccg cggcctcacg atcgtgccga
     6061 tctacggcga ggtgcaggtc gcgatcctgc ccaaggagca cgcgcacgcc accgccgacg
     6121 cggtcgcgat cgcggagctg gcggacgagc tgctgctgca gccggccgac caggtgccgg
     6181 gatgggccgg gcgcacggcg ggcgcggatc ccgtcccgat gcccgacgac gtcgccgcgg
     6241 ccgtcgagct ggtcgccgcg ggcgtcggct tcgtggtggt gccgcacgcg cttggccggc
     6301 tgcacgcgcg caaggacgtc gtcgcggtgc cggtgcacga cctgccggag acgcggatcg
     6361 ccgtggcctg gcgcgagggc gacgcctccc ccgagatcga ggagctcgtg ggcatcgtcc
     6421 gcgggcgcac cgccgcgagc tcccggtcgc agcgcgacga cgacgagcgc gaccgccgga
     6481 agccgaccgc cgcgcagaag accgcgcgca aggccgcggg caagccgggc gccgcgggcg
     6541 ggaagggcgg gtcgaagccg accccgaagg gcggcgggaa gcgcactccc ccgccgcgcg
     6601 gccagcgacg cgggcgctag ggaccagggc gggcggatcc gtcggccggc tcaggccggg
     6661 cggcgccccg cctgcaggtc ggcgaccacg cgacccacgt gcgcgcccca gcggcggtac
     6721 atggacgcgt agcggaactc gccgtcctcg aagtcgacgg gacccgcgtc cggcagcttc
     6781 accgacgtga cctgcgggaa gcgcgcgcac acctcggcct tgcgctggga gaggtacatc
     6841 gcgtgatccc ggaagaggcc ccggacgaac gtgccggcct ccacgtactg cgacacctgc
     6901 ggcacgtccg agacgagcac gatcgagttg tcggcggtct gctccacgag gtggtcgagc
     6961 aggtcctcga ggcggtggac ccagggggtg atgcgcgcga gctcgagcgc gtcggcgacc
     7021 ccgggcatca cgagcacgac gtcgtagcgg tgcagctcgg tgatctgccg cacggcctcc
     7081 tgcgtggcgg tgaggtgctg gtcggcgagc ggcaccgtgc gccactcgac gccacggccg
     7141 gtgatcgcgg cgagcgcccg cgccgactgc gccgccaccc cctccgcgtg ggtgcgcagg
     7201 cccacgccgg atccgccgat gccgccgagc gcgaggacgc ggtccggatc cgggcccgcc
     7261 accacgccga cgggcgcatc cgtcggcacc gtcgcggtca gcggggtcgg gatgccgccg
     7321 cgcaggctcg ccgccacgaa gggacggacg gtctggtgga ggaggcggat cggcgatgac
     7381 atgggctcct ggggatcgag gggcgaccgt cgatcatgcg ctgaccgtgc ttcgaccacc
     7441 cccgtgtcgg aggcacagcc tatcgtcgtc cacgagcacg gccgggtgct cgcgcccccg
     7501 tcctgacacc tggagcaccg atgatccgcg agcccgagcc cctcgtcccc caccccccgc
     7561 acgcccgctt ccaccagggc gcctggcgcg tgcaggtcgc gtcgcagccc gtcctcggct
     7621 acgtggtgcc cacggcgcgc acggccggcg cggatcccgt gttcgaggtc tacgccgacg
     7681 cggtcgacga ctccggccgg cgggtgtggg tctcgacggc cgtcacgctg gaggacgcgg
     7741 tcgcgtggat gcgcgagcac gacatggagc tgctctcgtt cgcgggcgag cacgcccgtc
     7801 gccgccgcga gctcgccacc ggcatgatgc cgacgcacta ctgagcgagg agccggccgc
     7861 tgcgccgcgc gaccgcggcg acgagcggct gcgcgagggc cagcgccagg cacagggcgc
     7921 cgagcacgtc ccaggtgccg gcggcgtgca ggtgcgcgat gagctgcgtg ccgaggagcg
     7981 gtcccaccat cgcggcgacg ccccagctga tcccgtaggc cgacaggtag cgcccccggg
     8041 cggcggcggg cgcgatcgcg gcgacgaggg ccgtcgcgcg acccagcagg atcaggtcgc
     8101 cgaggctcca gaccacggtc gccgcgacga gacccgggag gccggcggcc tgcccgacga
     8161 gcgcgaagcc gagccccagg aggacgaagc cgaccgccat ccccgccgtg ctcccgaggc
     8221 gggacgccgg gccgcgcgcc aggaggggct gcccgagcac gatcgtcagg gcggagacgg
     8281 cgagcaggat gccgagcgac gcggggtcga tcccccgttc ggccagcgtc agaggcaggg
     8341 cgacgtcgat ctgcaggtag agcaccgcga agcccgtgcc ggtggcgagc atcacgagca
     8401 gcagcgggtc gcgccacggg ctgcgcgcgc cggccaccgg agcgggcgcg tcacccgccg
     8461 gctcctcggc cgcgaccggg gatccccgac ggagcccgac gagcacgagg gcggcgcagg
     8521 cgaggcagct caccgcgtcg gcgacgaaca gcaggcgcag gtcgatgccg cccaggatcg
     8581 ccgcgaggac gccggccgcg acccccgcga ccgcgagtgc cgccccgtag aggccgtacg
     8641 cggcgacccg gtcgcggtcg tccgtgacga ggtccgcgat gagcgcctgc gaggccggct
     8701 cgtagacctc gaacgccagg ccgaggagca cggcggccac cgcggcggtc gcgatgccgg
     8761 gagccgccgc cagcatgagc tggaaggcgg cggtgagcgt caggccgagc gcgatcgtgc
     8821 tccgccggcc gagcgcgtcg gcgaggagcc cgccgaggat ccgcgacggg atcgtggcgg
     8881 ccccgaagag cgcgacgacg aggccggcgg tcgcgagcga cgcgccgagg tcgacggtga
     8941 gcaccaccgt gaggaacggc agcgtgaacg cgccgagccg gttgacggcc cgggcgagga
     9001 cgaggatccg gacctccacg gggaggcgcc gccacgtcac gacgcggccg gggcgcacgt
     9061 ccgtcacgtc gtcgtcggct gcctcgtcca tgcgcccacc cgccgtccgg gtcaggcgtt
     9121 cgtgagccag tacgcgatga ggagcatcgt caccacgaag ccggacagga agttcaggcc
     9181 gaggaagcgg cgccagccgc ggttcgcggc tcccgcgtcc tcgtcgcgga tcgaccagaa
     9241 cggcgcggtg ctcaggatgt acgggatcac gagcacgctg gcgatgatac ccggcagccc
     9301 ggtgaacagc atcgcgaccc cggccgcggc gtacgcgagc acggcgatcc gcacggtgac
     9361 ggccccgccg agcacggtcg cgatggagga gatgccgccc tcgcggtcgg ccacgatgtc
     9421 ctgcaccgcg ccgaacgcgt gcgaagcgac cccccacagg aagaacgccg cgaggatcgc
     9481 ccacagcgcg ggcgtgaacg cgccgcccgc gagcacgatg ccgtagaccg cgggggacgt
     9541 gaagtgcgtg ctcgaggtga gggagtcgag caccggccgc tccttgaagc gcaggccctt
     9601 cagcgagtac gcgatcacgg cgaagacgct cacagccagc accgcgacgc tcgccgcgga
     9661 tcccacggcc acgaggtaga cgaggaacgg cacgttcgtg acgagcacgg cgatgagcac
     9721 cggccggtgc atggcccgcg cgagcaccgc gccctccacg ccgcccttcc gcgggttccg
     9781 catgtcggac tcgtagtcga agacgtcgtt gatgccgtac atggcgaggt tgtacgggat
     9841 gaggaagtag agggtgccga ggatcgccgt gaggtcgaga tcgcgcgtga ccgtgaggta
     9901 cgcggccgcg aacgggaacg ccgtgttcac ccaggagagc gggcgggacg acagcgcgat
     9961 ggtgcgcagc gtctccgcgg cgcccggacg cgcgcgcacg tcactcatgc gcttcgatgc
    10021 cggacacgct gcggcggcgg cgcagcaggt accagaccgc ggggagcagc acgagggcgg
    10081 cgatcgcgta ggcgaagtcc tcgacgggcg cgtagccgag gatgaggccc accagcttgt
    10141 cgtcgtcgta gccgacgagg ccgaccttga tcatgatgtt gtcgaagatg agcgtcatca
    10201 cgagcaggat caggacgggc atccgccggt accagtagta ctcggggtag tcgaagcggc
    10261 tggatccgta gggcaccgcg ttcgcctcgc gcagcagcag gcggcggaac aggaacccca
    10321 cgaccgcgac ggggagcagg aacagcaggt cgagcgcgag gtagctcatc ggttcgcgcg
    10381 ctccctcgcc cgggcgacgt ggtggtcggc gaggcggctg aacccgttga cgaggttcat
    10441 cgtgaggtag cagagcagcg cgaggaagaa gacctcctcg agcggcagct ccgggcccac
    10501 gaggatcccc gtcatgaacg cggtctcccc gcggaagaag atgccctgcg agatgcccgc
    10561 gatgtcccag gcgaggaaga aggcgacgcc gatgagggtc gtgaggatcg ccgccgtccg
    10621 gtcgcgccag aagaacaggc gccaccgccg gtcgatgagc atcatgcagc cgagcgcgcc
    10681 gagcagcagc accaggtaga cgaggcccat cagacgaccg ggcggccgac cgtgcgcacg
    10741 agcggcacgg cgcccgggcc ggtcgacgtg tcgccgcgga ggcgcttcac gaggatctcc
    10801 gcgctgatga ggcacatggg caggccgatg ccggggatgg tggatccgcc ggcgtagtgc
    10861 agcccgtcga ccttcttgct cgtgttgccg gcgcggaaca tggccgactg cgtgagcgtg
    10921 tgggcgggcc cgaggatggt gcccttccac gagtgcaggt cggcggcgaa gtcgccgggg
    10981 cccgaggtgc ggcggaggac gatgcgctcg gcgaggtcgg ggatgccggc ccagtcgctg
    11041 atctgctgga tggcgcggtc ggcgatctcc tcgacgcgcg cgtcgccggc gccgtcgatg
    11101 ccgccgcggc cgatggtcgg gtcggcgggg atgggcacga ggatgaagac gttctcgtgg
    11161 cccgcgggcg cgaccgatgc gtcggtggcg ctgggcttgc agacgtagag gctcgccgga
    11221 tccggcacgg aggtcgtgcc gcccttcggc gggaagatgc gggagaagtt ctcgtcccag
    11281 tcctccgtga acagcagcgt gtggtggtgc agctcgggca gctcgccctc cacgccgagg
    11341 tagacgagca cggcgccggg gcccgcggtg gccttgtccc agtacgcctg cgggtaggtg
    11401 cggaacgcct cggggatgag ctcggtctcg gtgtgatgca ggtcggcggt ggagacgacc
    11461 acgtcggcgt cgagcgtctc ggtgccggcg tcggtggtga tctgcacgcc gcgcgcccgc
    11521 gccttgccgg ccttcgtcgg ctcggtgagg atgcgcgaga cgggcgcgcc cgtgcggatc
    11581 tcgacgccct cggcgcgcgc gacccgctcg atcgcgtcga tcacggtgat gaggccgccc
    11641 tgcgggtaca gcacgccgtc ctcgaggtcg aggtggctca tcaggtggta catgctcggc
    11701 gcgagcttcg gcgacgagcc gaggaacacg gcagggtagc cgaggatctg gcggaggcgg
    11761 cggtccttca cgtagcgggc cacgtgcgtc tcgagcggcg tgagcagcag cttcccgagc
    11821 gtgcccgtgc gggtgacgac gtcgcgcttc agcagcgacc ggtagtcggc gaaggtcgtg
    11881 tagaggaagc gcttcttcgc gacctcgtag acgtccttcg cggagtcgag gtagcgggcc
    11941 atggcggggc gggatccggg ctcgacgctc tcgaacaggt cgaggttggc ctcgcgggag
    12001 tcgcggatgt cgatggggtc gctctcgccc tcgaacagca cgcggtagcc ggggaggcgc
    12061 acgaggtcga gctcgtcggc cgcgctcgtg cccaacagac ggaagaagtg gtcgaacacc
    12121 tcgggcatga ggtaccagct cgggccgagg tcgaagcgga agccgtcctt ctcccaggag
    12181 ccggcgcggc cgccgacctc gtcgcggccc tcgacgaggg tgacgcggta gccgtcgcgg
    12241 gcgaggagag ccgcggaggc gaggccggcg atcccgccgc cgatcacgat ggcggtgggt
    12301 gcggtcatgg cgctctcctg ctgctcgggg tcggacgggg cggggtcgga cggggcgggc
    12361 tcggtcgggg cgggacgcga cgcgggggcc gggcgggcgg catgcgcgcg gggtccgcgg
    12421 gagcggcgca cgaggcggcc gtcgaccccc gacggctcag cgcccgacgc ggcggcgagc
    12481 gcgatgcggg ccttcacggg atccggcacc cgcacgcgcg tccgcacgag ctcggacgcc
    12541 ggggtgtcgc gcaggcgcac ggcgagctcc gcgaacaggc cctgcgcgag cgcgacggcg
    12601 cggcggctgg aggcgggcag gtcggggatc acggcgccgg acacgcggag gtcgtggtcg
    12661 atgtcgtcga ggatgcgctc cttgtcggcc tccgagaagg aggcgacgtc gacgccgggg
    12721 aagtagctgc ggccgagcgc gccgtggtcg gcggccaggt cgcggaggaa gttgaccttc
    12781 tggaacgcgg cgccgaggcg cttggcgccc tcctcgaagc ggatccgctc cgggcgcgtc
    12841 gtcgcgtggc cgaccaggaa cgcgcgcagg cacatgaggc cgacgacctc ggcggatccg
    12901 tacacgtact ccgtgaagga cgcgggcgtg tgctccatcc gccgcaggtc catgcgcatg
    12961 gaggcgaaga acggcgcggt gagctcggcg ccgaagcccg cgcggcgggc cgtgatggcg
    13021 aaggcgtgga cgacgaggtt ggtgctgtag ccgcggagca tggcgtcctc ggtctcctgc
    13081 tccagcgcgt cgagcagctc ctcgacgtgc gccggatcca cgccggcacc ggccgcggcc
    13141 ccgtcgacga tctcgtcagc cacgcgcacg agcgcgtaca cgttctcgat gtgctggcgg
    13201 acgtcaggcc cgagcaggcg cgacgcgagc ccgaaggagg tggagtagcg gcggatcacg
    13261 acggaggcgg tctcctgcgc gacgcggtcg tacttctcga ggcccgtggg ctcctcgggg
    13321 gcggcgggcc ggcggccggg gaggcgacgg gtcatcggat gcgcccgagc acggactccg
    13381 cgacgggcgc gagctcccgg cggagggcct ccggcacgac cgggtcgtcg aggcgcgcga
    13441 cggcggcgac cgcgaggtcc cgcgcgacgc cctcggcgta ggtgcgggcg cccgagctct
    13501 ccagcaccga gcggacgagc gccgcctcgc cgcgggagag gtcgtccttg cccacgagcg
    13561 cgctgatctc gccccactcc gacgaccgca cggcgtgcgc gatgagcacg gtgcgcttgc
    13621 cctcgcgcag gtcgccgagg ttcgtcttgc cggtctcctg ctcgtcgccg aagacgccga
    13681 gcacgtcgtc gaccacctgg taggcgatgc cgatgtcgcg gccgaagtcg ccgagcgccg
    13741 cgacgacctc gggtcgcgcg cccgcgagca ccgcacccgc ctgcagcggc gcctcgaacg
    13801 agtacacggc ggtcttgagc cgctccatgc ggaggatctc gtcgacgctc ggcacgtccg
    13861 cggtgagcga gaactcgacg tcgatgagct cgcccgcggc cgacgcgaac acggcgtcgt
    13921 cgaggagctc caggaggtgg gaccgcgtca ggtcgcgcac gccgctcgcg tcgatgaggc
    13981 ggtaggcgtt gacgagcgcc agatcccccg cgatgacggc ggccgacatg ccgcggtgct
    14041 cggcgagcgg ctggggcagg ccctgcgtgg tggcgatgtc gcggtaggcg ccggagacgt
    14101 tggggccgcc gcgccgggtg aagtcgcggt cgatgacatc atcgtggacg atgagcgcgg
    14161 tgtggagcat ctcgaacgcg gcgccgacgt gggcggctgc ctgcacgtcc tggcccccga
    14221 ggccgtcgta cgcggccatc accatgcgcg gccggaaccg cttgccgccg gccgtgttcg
    14281 actcgagcgt gcgccacagc ttcacgtact cggggcccat gacctcggcc cggacgagcg
    14341 agcgggcgaa gaacgcatcc agcacgccgt tcacatgggc ctgcctcgtg gtggagacgg
    14401 cagcgaggtt ggtggcgtcc acggatgaaa cctaacatcg agggggtaac ggaaagcagg
    14461 gagcgcatgt cacagcacac cgagctcgtc gtcctcctgg acgacgacgg cgagcccatc
    14521 gggacggcgc ccaaggcgac ggtccacacc cgcgacaccg cgctgcacct cgcgttctcg
    14581 tgccacgtgt tcgatcggca aggccggatc ctcgtcacgc gccgcgcgat cggcaagctc
    14641 acctggcccg gcgtctggac caactcgttc tgcggccacc ccgcgcccga cgaggacatg
    14701 ctcgaggccg tgcaccgccg cgccgagcag gagctggggc tcgagctcgc gtccgtcgag
    14761 ctcgtgctgc ccgacttccg ctaccgggcc accgacgccg cgggcgtcgt cgagaacgag
    14821 atctgccccg tgttccgggc gatcgcggcc acgccggtgg atccgcggcc cgaggaggtc
    14881 ggcgaatacc agtgggtgga tcccgaggag ctcatccccg cggtcgccca cacgccgtgg
    14941 gccttcagcc cgtggctcac gctccagctg ccgttgctgt acccggagca cgcggcgcac
    15001 gcggggctgg cggacgcgga ggccgacgcc gacgcggtgc ccgccgcctg atccgttcgt
    15061 ctcctcggga tcggcgccgc agccatcgct gggggcgacc ggcccgaggg cgcggccgtc
    15121 gcccgtagcc tccgcgggtg gaatccgaat cggcgcgtgt cacccgcatc cgtccgttct
    15181 acgcgtcgca ggtcgacgcc tacgacgcca tcgtgagcgc tccggtcgag ggctggatcg
    15241 aggagatccg cgggcaccgg acggacgggg gcctgctcga tgccggctgc ggcaccggcc
    15301 gccacgcaga agctctcgcc cgggcgggat tcgaggtgga gctggcggat gcctcgccgg
    15361 ccatcctcgc ggtggcgcgc acgcgcaacc cggggatccg cgcgcacctc gcggacatct
    15421 gcacggtgga cctcggccgc cggtacgacg tcgtcgcgtg ccgcggggtg ctgaacgaca
    15481 tgctcagcga cgtcgagcgc tccgccgccg tcgagcgcct cgccgcgcac gcggcccccg
    15541 gcggcgtgct ggtgctcgac gtgcgcgacc gcgacgccac ccgcgaccgg gccggccgca
    15601 ccaccacgac ggagggcgcg ctgcccgacg gacgcaccgt ccggttccgc agcagcacga
    15661 cctgggcgga tccgctggtg cgcgtgcgcg agctgcacga gatcatcgcg cccggacgac
    15721 cgaccgagtc cgagccgttc gacttcgcga tgcggccgtg gacgcggcgg gagctcacgg
    15781 acgcgctcgg cgcagcgggc ctggtcgacg tcgtggtcga cgcggcggcg catcgcccct
    15841 ccggcgaccg gctggtcgcg tcgggacggc gcccgctctc gttcgccggc tgagggcccg
    15901 gccgcgcacg cggacgggcc ctcatcgtgg tgcgggcggg atcagcccca gaaggcgcgg
    15961 atctcgtcgg cgacgcgctc ggcctggcgg cggcccgcct cggcggaggc cttgcgggtc
    16021 gagagcagga gcgagttctc gccgaacgcg gcggtgctgt cgtcgtcggc ctggatcacg
    16081 agcacgtcgg cccggccgcg gagctgctgc acgacggtgg agagggtcgg gcccatgccg
    16141 ctctgcgggg cctcggggcc gcacgcgatg acgaggatcc gctcgtgctc ggcgacgacg
    16201 tcggcgttcg tgccggagcg catgccgccg tccatgtagg ggcggccgtc gatggtgacg
    16261 ggcgggaaga cgccgggcac ggcgcagctc gcggcggacg cccgcacgag gtcggcgccg
    16321 gaggccttgt cgaagacggt gaagcggccg gtgccggcgt cgaccgcggt gatgcggaga
    16381 tccgcctcgg gccagtcgcg gatcgggagc agctggccga tgcgctcgac gctcgcggcg
    16441 tcgtccacct cggggtcgta ctcctcgagc gcgaactcgc cgatcttctg gcgcgtgggg
    16501 atctcgcccg cggtgctcac gatgccctcg ccgatgacct cgatggtgcg ggagaggtcg
    16561 cggctgccca tcggctccgc catgccggcc acgtcgacga agtgctcgtc gtaggcggcg
    16621 tcgatggcgc ccgcccgcag gttgatggcg acgacggatc ccgccgacgt gccgaccacc
    16681 gcgtcggccg cgccgaggtc gacgcccgcc gcgaggaggc cggacaggag gcccgtctcc
    16741 cacgcgatgc cggcgacgcc tccgccgccg aggacgagcc cccgcgtcgg cgtggtcgtg
    16801 tcccgctcgg tgccggtcat ggtcctcctc ttccgcgggc ccgggcctgc gtgctcgtcg
    16861 tgatggtggt tgatgcggct ccatcatccc cgaacacggt ggacggcgcc cgagcgcccg
    16921 atgcacgcac ggtggacgcg ggcgggctca gcgcgcggcg gacggatccg cggcggatgc
    16981 ggacgcggcg ggaccggcgg gacccgcggc cgcctcccgg tagacctcgc gcacctcgcc
    17041 gaggaaccgc gtcacggcgg cgcgctccgc gtcggtcagg gcgtcggccg cgcgcgcgac
    17101 cccgccgatc atgggcatca gctccgccat ggcctggccg acggaggccg gccgcgggac
    17161 gacgacgacg cggcggcggt cgtgcgggtg cggtcggcgg tcgacgtggc cgacctcgac
    17221 gagccggtcg accacgagcg tcgcggccgc ggtggagacc ccgagacggc cggccagctc
    17281 cgtgggcgac agcgacccct cctggatgag gtgctccatc gccttcatgt cggtggggtt
    17341 gacctcgagc acaccgccga gccggcgctc gaacccggcg gcgaggccca gcacgttgcg
    17401 gaggatccgg ccgagctcgc cggccgcgcc cgcgtccgcg gggacgcccg cgccgggggc
    17461 gggcagggcc gcggcggctg ccgtcggggc ggcgggcgcg tccggatcgg ggcggggacg
    17521 ggcgcgcgac atgctgccat ggtacgccgc aggtagctaa gccgcttgat catcagtagg
    17581 ctgactatca ccgcacccct ggaggacctg tgagatccat cgcccgcttc gtcagcgccc
    17641 gccgcaccgc ctggatggcg ctcgtcatcg cggtcgccgc cgtcgccgcc ctgttcgcct
    17701 tcctgccgaa gggcgaggcc gacgccttcc cgccctccgg cctgccggac tcgagccagg
    17761 cgaagcaggt gagcgagctg ctcgagcggt tcccgagcgc cgacacgacc gtggggatcc
    17821 tcgtcttcag ccgggacggc gccgcgctca cggacgccga caccgccgcg atcgcgcagc
    17881 gcgccgaggc cctggccgcc gactcgatcg ccccgcaggc cgtcgtgccg caggccagcg
    17941 acgacggccg cgcggcgctc gtcgccgtgc cgctcgacgc gtccgcggtc gccgacgacg
    18001 tcgccgggac cgccgcgacc ctccgcacca cggcatcgga cggcctcccg gacgggctgg
    18061 tcgctcaact caccggcccg gtcggcttcc aggccgacat ctcgaacgcg ttcgcgggcg
    18121 ccgacttccg cctcctgctc gtgacggtgc tggtggtcgc ggtgctgctc atcgtcacgt
    18181 accggagccc cgtgctctgg atcgtcccgc tcgtcgtggt cggcgccgcc gacggcctgg
    18241 cgcgcgtggt cgtgacggcc ctcgcggatc cgctcggcat caccatcgac gcctcgatcg
    18301 gcgggatcct ctcggtgctg gtcttcggcg ccggcacgaa ctacgcactg ctgctcgtgg
    18361 cgcgctaccg ggaggagctg acgcgccagg aggaccgcca cgcggcgatg ctcacggcgg
    18421 tcacgagcgc ggggcccgcc atcgcggcga gcggcggcac ggtcgcgctc agcctgatca
    18481 cgctgctgct cgccgagctc tccggcaacc gcgcgctcgg gttcgcgtgc gctatcggcg
    18541 tgctcatcgc gatcgccgcc gccctgctcg tgctgcccgc ggccctcgtg gtctgcgggc
    18601 gcggcctctt ctggccgttc atcccgcgcg ccgggaccga cgccgaccac ggcgggaagc
    18661 cgggcgtgtg gcggcggctc ggcctcgggg tccggcgtcg ccccgcggtc gtggccgtcg
    18721 tcgccctcgc cggcgtcggc gtgctcgcgc tcggcctcgt cggcgcgcgg gtcggcctgt
    18781 cgcagacgga ccagctgctc ggcgaccccg agtcggtcgc tgcccaggag gtcgtcgacg
    18841 cctcgttctc cgccggcctc acggcgcaga ccgtcgtgct cgcgccggac gcggtggccg
    18901 acgacgcggt cgccacggcc gagtccgtcc ccggcgtcgc gggcgcccgg gcgggcgagt
    18961 cggcggaggg ccgcacgcgc atcgacgtgc agctcgacgc cgagcctgag agcgccgcgg
    19021 ccttcgccgc ggtgcaggac ctccgcgacg cctacgccgc cgcgccgggc gagcagtcca
    19081 cgaccctcgt gggcggcagc gacgcgaccg ccgccgacac cgccgcctcg tccgagcggg
    19141 accaggggct gatcatcccg atcatcctgg ccatcgtgtt cgtgatcctc ggcctgctcc
    19201 tgcggtcgct gatggcgccg gtgctcctca tcgcgagcgt gctggcgacc ttcttcgcga
    19261 gcctcggcgc cgcgaacgtg ctcttccagc aggtgctcgg ctttcccgcg ttcgacgcga
    19321 acgtggtgct gttcgcgttc ctcttcctgg tggcgctggg cgtcgactac aacatcttcc
    19381 tcgtgacccg ggcgcgcgag gagcggcgac tgcacggcac gcgcgagggc atggtgcggg
    19441 cgctggcatc caccggcggc gtgatcacga gcgcgggcat cctgctcgcc gcggtcttcg
    19501 cggtgctcgg cgtgctgccc gtcgtggcgc tcacgcagat cggcgtcatc gtctgcatcg
    19561 gcgtgctcct cgacacgctc gtggtgcgga cgctgctcgt gccggcgctg gtcttcctgc
    19621 tgggcgaccg gttctggtgg ccgtcgcacc gcggcgcgcg gcaccgtgag acggtggacg
    19681 catgagactc gccgaggcgc tgatggaacg gtccgacctg cagaggcgca tcgagtcgct
    19741 gcggaacagg atccaggcga gcgcccggta ccaggagggc gaggatcccg cggaggacgc
    19801 agccgcgctg ctcgcggagg cgggcgaggc cgtcgacctg ctggcggcgc tcgtgacgcg
    19861 gatcaacctc acgaacacgg ccgcccgcct cgacgacggc acgccgctca cctccgcgct
    19921 cgcccggcgg gacgccctac ggacgcggca cgggatcctc acggccgcgg ccgacgccgc
    19981 ctccggacgc gtcgccgcgg gcgtgtacgc gcagcgccag ctgcggagcg agctgcggct
    20041 gatcgccgcg ctgccgatcc gcgaggtgcg cgaccgggcc gacgacgcgg cgaaggagct
    20101 gcgggagctg gacgccagga tccagcgcgc gaactgggag gtcgagctgg tcgaggaggc
    20161 gtaggggcga gtcggtagtc gtccggagcg ggcacacccc ggcggatcag cgggcaacct
    20221 gatcccctgt ggcgcggagg gcagcgcacc cggcgagagc cgagcacacg tcagccccgc
    20281 acctcgcacc gggaacggtg cacgggtaca gctcaccacc acgtgccggt cggacgacga
    20341 gggagggttc ggggacctcg cccccgcgtg atgcgggccc ggtgcgatgc gcgccgggcc
    20401 cgacgtcatg cgcggccgcg tcgctgcgcg gcctttttca gcggatcagt ccgcgaggtc
    20461 ccgcaggtcc tccgcggtgg cggtgcaggt gaccgtggcg ccgtccccct cggcccgctg
    20521 ctcggtgacg atgtggtcgc ccacgaggat ccggcaggtg atgtcgccgt ccgccgagac
    20581 cgtcgggtcg acgctcgcga ccgcgctcac ggagaacgcc gccatgtcga agtcggtggt
    20641 gtccgggatg acgacctcgc ggctgaacgg gagcggctgg tcggacgcct gctcggatcc
    20701 cgcggtgccg ccgacggagg tggtccagag gacgcccgcg gtgaccgtgc cgcccgagcc
    20761 ctccacctgg tacgtgacgc gcggctcgtc ggacgcctcc gccgacgacc gcgcctcgga
    20821 ctcccgcacc gcgcccgtga tggccgtgac gatgcctgcc gtgtagacga tggcgagcac
    20881 gatcgagagg atcagcgcga cgatgctcgc gatgaggccc ccgagcgcca tgcccttggg
    20941 ccggtccttg aggatcaggc cgatgatccc gagcacgatg ccgatggccg cgaggaagcc
    21001 cgacacgtag ttgaggatcg ggatcacgga gccgatgagc gacagcacgc ccacgatgag
    21061 cgcggcgagg ccgacgccgt tgaacgtctt gcgctcgcgg ggtgcgctgg tgtcgggttc
    21121 gggcgcgtag ctgaaggtca tgcatcgacc ctgccaggga tgcgggcgga tccggccgtc
    21181 gcggggtcac gatcccgcga cggccgggcg ggcgtcaggc ggcgagcacg tccgcgaccg
    21241 gcgtcagcgg catctcgagg gcggcggcga cgtgcgagtt cgtcacgtgc ccgtcgtgga
    21301 cgttcaggcc cagggcgagc gccggatcct ccgcgagggc ccgcttccac cccttctccg
    21361 cgagcgcgat cacgtacggc agcgtcgcgt tggtgagcgc gcgcgtggaa gtctccggca
    21421 ccgcgcccgg catgttggcg acgcagtagt agacgctgtc gtgcacgtcg aaggtggggt
    21481 cgtcgtgcgt ggtggggcgg gatccctcga agcagccgcc ctggtcgatg gcgatgtcga
    21541 cgagcacgga gcccttcttc atggtggcga ccatcgcgtc ggtcacgagc ttcggggcct
    21601 gggcgccggg gatgaggacc gagccgatca cgagatccgc gtccttcagc tgcgctgcga
    21661 tctcgtacgc cgaggagacg cgcgtctgca cctgcccgcc gaagcggttc tcgagctcgc
    21721 ggaggcgcgg gatggagagg tcgatgatcg tgacgtccgc gcccatgccg agcgcgttcg
    21781 cggccgcgtg ctcgcccgcg acgccgccgc cgatcacgac gacgcgcgcc ttcggggtgc
    21841 cgggcacgcc gccgaggagg atcccgcgcc cgccggccgc gcgcatcagg tggtacgcgc
    21901 cgacctgggt ggagagccgg ccggcgacct cgctcatcgg ctggaggagc ggcagctggc
    21961 ggttcgggag ctgcaccgtc tcgtaggcga tggccgtggt gccggaggcg acgagcgcgt
    22021 ccgtgcaggg ccgggacgcc gcgaggtgca ggtaggtgaa gagggtctgg cccgggcgca
    22081 tgcgcgggta ctcctcgaga atcggctcct tgaccttgag cagcagatcc gccgcgcccc
    22141 acacctcgtc ggccgtggcg acgatggtcg cgcccgcctc gacgtagtcg gcgtcggtga
    22201 tgctcgatcc gagtcccgcg ccctcctgca cgagcacctc gtggccgcgg cgcacgagct
    22261 cgtgcacgcc cgcgggcgtc gcggcgaccc ggttctcgtt gttcttgatc tcggtgggga
    22321 tcccgacctt catgcgcgtg ctccgtctcg tctccccgcg aggtgcggcc ggcggcagcg
    22381 atgcgggagg gcgagactca tggtggccat cgtgcgtttc gagcgcgtga actccgtagg
    22441 atcgtcggcg cggtcgcctc atccggtgcg atcctgcggc gtgaaaggct ggtcgagcga
    22501 tgccgacgaa ggaaatgcgg acgcccgagc cgctggatgc ggtcgaccgg aagctcgtcg
    22561 ccctcctccg ggccgacgcg cgcaccccga acagccgcct cgcggagcag gcgggcatcg
    22621 cgccgtcgac gtgcgtgacc cgggtgcgcg gcctcgtgga gcgcggcgtg atcaccgggt
    22681 tcaccgccac catcgacgcg gatgcggtgg gcgtgggcct gcaggcgctc atcagcatcg
    22741 cgatccgcgc gggcgcccgc cacgagatgg ccgccttcgc gtccgagatg cgggagctag
    22801 ccgacgtggt gcagctcttc ttcctcggcg gatccgagga cttcatcgtc cacatcgccg
    22861 tccgcgacag cgaccacctc cgcgacttcg tcctgaagca cctgtcggcg cacccggccg
    22921 tcgcgtcgac ccgcaccagc gtggtcttcg accaccacta ctcggggccg gcggtggggg
    22981 atccgggggc ctagcgcgct agacggcggg ctactccccg ggctgccccg cgtccgtcac
    23041 cgtcacgtcc gtgtgcacga agttgaggta cgagcgggaa gccgtggggc cgcgctggcc
    23101 ctggtagcgg gaggcgtact cgccggatcc gtagggcttc tcggcgggcg acgacaggcg
    23161 gaagaagcag agctggccga tcttcatccc gggccagagc ttgatgggca gcgtcgcgac
    23221 gttcgacagc tcgagcgtga cgtggccgga gaacccgggg tcgatgaagc cggcggtgga
    23281 gtgcgtgagg aggccgaggc gaccgagcga gctcttgccc tcgaggcgcg cggcgacgtc
    23341 gtcgggcagc gtgaccagct cgaacgtgga tccgaggacg aactcacccg ggtgcaggat
    23401 gaacggctcc cccggcttcg actcgatcag gcgcgtgagc tcgggctggt cctcggcggg
    23461 gtcgatgtag gggtacttgt ggttgtcgaa cagccggaag aagcggtcga tgcgcacgtc
    23521 gatgctcgcg ggctgcagca tcccggggtc gtacggatcg agggccactc gtccggcgtc
    23581 gagctcggcg gtgatgtcac ggtcggagag gagcacggca ggagcctacc gggggctggg
    23641 tggcgcccgg ccggactctt gctaggctgt ggtctcgacc cggctcccgg ccggtcgcgc
    23701 gagtgtagtt caatggtaga acttcagctt cccaagctga tagcgcgggt tcgattcccg
    23761 tcactcgctc catctgcgaa cgtttcaact cggttcaccc gcggcacatg tccgaaatcc
    23821 ttggctgagt tgaagtccca ttgctcacgt cggggtccta tgggcaaagc gatgtcctgc
    23881 gcactcggcg acaaagcctc acttcgccct cgaacatcca acccatgcgg ctactgaggt
    23941 gctcgatcgt tagtgatcca tgcaaaagca acctccagcg aggaacaagc cgctgcccga
    24001 gtgtcgggca tgttgcccgc atagccttgc cactgccctt cctctagctc agcgcgcccc
    24061 caaacctccg cgtagatact cggcccggcc ccatgccgag acactaccca cacctcccgt
    24121 tcgtcctgcc gccaggcatt gaaggtataa ccgcttcggg aattttcgaa cgttagccga
    24181 tggggagtca cttcttgcat gatgatcaca ggtaaacact aaccggcaac ttggcgcggt
    24241 tccaaccatt cgacgacacc tttcgacccc agctgccccc aattgtgggg ccatgtgagt
    24301 taaggggttg cgctcggcgc atcaactact taaccatata aacgacgcca cccacagaac
    24361 aggttctgaa aaagcggatt cgccttagct gggacgtaaa aacgttcgta gccaatacgg
    24421 tg
//
