LOCUS       NZ_JADKRR010000002     22402 bp    DNA     linear   CON 16-AUG-2024
DEFINITION  Clavibacter sp. VKM Ac-2872 n2, whole genome shotgun sequence.
ACCESSION   NZ_JADKRR010000002
VERSION     NZ_JADKRR010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Clavibacter sp. VKM Ac-2872
  ORGANISM  Clavibacter sp. VKM Ac-2872
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1  (bases 1 to 503716)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Draft genome sequences of plant-associated actinobacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 503716)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2020) All-Russian Collection of Microorganisms,
            G.K. Skryabin Institute of Biochemistry and Physiology of
            Microorganisms, PSCBR RAS, pr. Nauki, 5, Pushchino, Moscow Region
            142290, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 675x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015351105.1-RS_2024_08_16
            Annotation Date                   :: 08/16/2024 04:34:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,385
            CDSs (total)                      :: 3,333
            Genes (coding)                    :: 3,309
            CDSs (with protein)               :: 3,309
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 2 of 24
            Pseudo Genes (incomplete)         :: 19 of 24
            Pseudo Genes (internal stop)      :: 4 of 24
            Pseudo Genes (multiple problems)  :: 1 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:57:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 232149
            Orig. end                         :: 254551
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADKRR010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22402
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22402
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22402
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12402](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12402)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(374..385)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(525..539)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.54"
                     /tool="antismash"
     gene            complement(756..1298)
                     /locus_tag="ITJ40_RS11410"
                     /old_locus_tag="ITJ40_11410"
     CDS             complement(756..1298)
                     /EC_number="2.3.1.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491332.1"
                     /locus_tag="ITJ40_RS11410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11410"
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="WP_194667190.1"
                     /transl_table=11
                     /translation="MSAEPVVVESAEPAGGIRVRRARTGDVPRIQQLVEPLVMEGILLG
                     KDLVVLYENVQEFRVAVDASGEVVGCGALHVMWEDLGEIRTLAAAPHTRGTGVGHALLE
                     RLEDDARELGLSRLFCLTFEVGFFSRHGYHEVAESIIAQEIYYEMLRSHDEGIAEFLDL
                     SRVKPNTLGNTRMLKAL"
     gene            complement(1350..1607)
                     /locus_tag="ITJ40_RS11415"
                     /old_locus_tag="ITJ40_11415"
     CDS             complement(1350..1607)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039453.1"
                     /locus_tag="ITJ40_RS11415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11415"
                     /product="hypothetical protein"
                     /protein_id="WP_194667191.1"
                     /transl_table=11
                     /translation="MDPVRRLMFWLRVPFVADAALVVIGVALLVGGDGVGWWVLVFAGL
                     RAVVGVVAIVWIAPRMIARLGGGSDTGAEPPAPDAGSARR"
     gene            complement(1611..3185)
                     /locus_tag="ITJ40_RS11420"
                     /old_locus_tag="ITJ40_11420"
     CDS             complement(1611..3185)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491334.1"
                     /locus_tag="ITJ40_RS11420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11420"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_194667429.1"
                     /transl_table=11
                     /translation="MTLRRRLVLSVVGLLALASILIGTVSILALRASLVQQVDQQLQAT
                     AARSSNLIDRDADQYGSFPGAPPGGLGAFGQQVGTISATIVDGVVSGGYIADRDAAEGE
                     PGGAGAVELTQVQSQQLQSVPTDGIPRTVDLGGALGRYRLVGDTAATGATLVTGLPMKP
                     ADDVVEQLIVVISVVAALTLALAAVLGAVIVRRALRPLDRVVDTATHVAALELDRGDVA
                     LEARVPASDTDERTEVGRVGAALNGLLGHVSAALSSRQASEAKVRRFVSDASHELRTPL
                     ASIRGYAELTRRGPHRLPEDVTHSLSRIESESVRMTTIVEDLLLLARLDEGRELETDPV
                     DLTRILLDTVGDASAAGPDHDWDLDLPDDSVTVPGDDARLRQVVVNLLANARTHTPAGT
                     RVVASLAVEGTGSDGHAVIRVTDDGPGIPPELQASLFERFVRGDGSRARSTGGTGLGLA
                     IAQAIVSAHHGAVWVESEPGRTVFGVRLPLERRAGDARPEAPAASDRWAPPSGDPVADR
                     PSPRAAG"
     gene            complement(3242..4015)
                     /locus_tag="ITJ40_RS11425"
                     /old_locus_tag="ITJ40_11425"
     CDS             complement(3242..4015)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulators consisting of a CheY-like
                     receiver domain and a winged-helix DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491335.1"
                     /locus_tag="ITJ40_RS11425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11425"
                     /product="response regulator transcription factor"
                     /protein_id="WP_012039455.1"
                     /transl_table=11
                     /translation="MMDPVTTTPPSGFQPAAAPQPRLTRADGSPIRVLVVDDEASLTDL
                     LQMALRYEGWQIRTAENGHQALAAAREFKPDAVVLDIMLPDLDGLQVLSRLRADAEDIP
                     VLFLTAKDSLDDRLAGLTAGGDDYVTKPFSLEEVVARLRGLIRRSTLVVSDSVDPVIRV
                     GDLTLDEDSHEVARAGDPIELTATEFELLRYLMRNPRRVLSKLQILDRVWSYDFGGKSS
                     VVEIYISYLRRKIDAGRNPMIHTVRGSGYMLKAAE"
     gene            complement(4086..4868)
                     /locus_tag="ITJ40_RS11430"
                     /old_locus_tag="ITJ40_11430"
     CDS             complement(4086..4868)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039456.1"
                     /locus_tag="ITJ40_RS11430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11430"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_194667192.1"
                     /transl_table=11
                     /translation="MPDAPDAPDAPTRAGLLWDEGDRAEALALLKEHLRDEPLDTGARL
                     ALAGLYRELIAPDQAGRWGIASPGWTTEVERDRLARMIAHSGIADHEIPAFLGLPPDAD
                     LPAEVRALTPAIDLHRADFADPARMTKRERKAARYASTPSSFAYEVVEVAAGFAWWLIG
                     IVFALGAVVVWVAALCGQPVTALARWTGTATLGTMAAACVAHAYVMRVDERRRRQREPD
                     SDPIDVDVLPWISGAILLGLVVAALVSMGLRVGDPLPF"
     gene            complement(5001..6029)
                     /locus_tag="ITJ40_RS11435"
                     /old_locus_tag="ITJ40_11435"
     CDS             complement(5001..6029)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039457.1"
                     /locus_tag="ITJ40_RS11435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11435"
                     /product="TerC family protein"
                     /protein_id="WP_194667193.1"
                     /transl_table=11
                     /translation="MNITTTTWLITIAVTIAFFVYEFFTHVRKPHEPTIGESARWSAFY
                     IGLALIFGVGIGFTSGWGYGGEYFAGYLTEKALSIDNLFVFLLIMTGFAVPRKYQQKVL
                     MIGIVIALIMRAGFIALGAALIENFSWVFYIFGALLFVLAYQQLKGDHGGNAADNLFVR
                     IARRILPVHDDFVGDRFTTKIDGKRFVTPLLLCVIAIGFVDLVFALDSIPAIYGLTNEA
                     YIVFTANAFALMGLRQLYFLIGGLLERLVYLSQGLAVILAFIGLKLVLHAMHVNELPFI
                     NGGQPMLWAPEIPIWFSLLFIGATITVATVASLAKTRGDKQKEDRASVDGETVTRATEE
                     KH"
     gene            complement(6165..7103)
                     /locus_tag="ITJ40_RS11440"
                     /old_locus_tag="ITJ40_11440"
     CDS             complement(6165..7103)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491338.1"
                     /locus_tag="ITJ40_RS11440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11440"
                     /product="PD40 domain-containing protein"
                     /protein_id="WP_194667194.1"
                     /transl_table=11
                     /translation="MTLRDGQLARLLVVDVETGAERMVAESAVLHIEAPNWTPDGRWLV
                     VNAEGGLWRLRAPEAEEPDPDLPEPAVDFQAVDLGGVPPINNDHVFSPDGAHVYVSGRD
                     GHLYDVLWNDGAGGQGRRITADRDPALRFKNYLHGVSPDGSTLSVIGGQVDARGEWTTN
                     IHLVPVDGGPTTQLTDDGFPDDGAEFSPDGGWLYFNSERGSDLPGHAQLFTMRVDGTDT
                     HQFTSDERVNWFPHPSPDGEHIVYLSFPPGTLGHPADHDVILRVIDRQSHRTRDLATFP
                     GGQGTINVTSWAPDSRRFAYVAYPFEAPSLT"
     gene            complement(7100..8164)
                     /locus_tag="ITJ40_RS11445"
                     /old_locus_tag="ITJ40_11445"
     CDS             complement(7100..8164)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039459.1"
                     /locus_tag="ITJ40_RS11445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11445"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_194667195.1"
                     /transl_table=11
                     /translation="MPQITTPVALFTGQWADLPLEEVARLASGWGFDALEIACSAEHLD
                     VWRAAEDPAYLRGRLEILERHGLRVHALSQHLTGQAVCDDPIDFRHQAILRSKVWGDGQ
                     AEGVRQRAAEELKLTAKAAAGLGVTRVTGFTGSRIWPYVAMFPPVPESVIDAGYQDFAD
                     RWNPIIDVFDDEGVRYALEVHPSEIAYDHWTTRRTLEAIGHRPGFGLNWDPSHMMWQGI
                     DPVGFLLDFADRIYHVHAKDTRVTSDGRGGRLGSHLPWGHPRRGWDFVSVGHGDVPFER
                     AFRALRSIGYDGPVSVEWEDAGMDRLHGAPDALAQVRSLLWPTPDSLFDSAFANNRDDA
                     PAATPADGTAGSTA"
     gene            complement(8273..9055)
                     /locus_tag="ITJ40_RS11450"
                     /old_locus_tag="ITJ40_11450"
     CDS             complement(8273..9055)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039460.1"
                     /locus_tag="ITJ40_RS11450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11450"
                     /product="ABC transporter permease"
                     /protein_id="WP_194667196.1"
                     /transl_table=11
                     /translation="MSAMLMPARPTAARRLAIYRAHVVSELAQNARMPAFVLPLLAYPV
                     LIYVVVGLPQGGPPSARLSVLLGYVLFSVLGTVTFQFGVGVASARESPWERWLFTAPVP
                     AWIRLAAKLTVACVFGVLFVIPVALVGFTVGGVRVDAATLAAVALAVLAGAVPMALLGL
                     AMGYWFPARGALGLANLVYLPLSFAGGLFTGGDTSGTPWESLTVLLPTGAWSTLTSAAA
                     RHDTATMGIPLILLAAWAVLLGGITLAGYQRTQSANFR"
     gene            complement(9052..10008)
                     /locus_tag="ITJ40_RS11455"
                     /old_locus_tag="ITJ40_11455"
     CDS             complement(9052..10008)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012297989.1"
                     /locus_tag="ITJ40_RS11455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11455"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_194667197.1"
                     /transl_table=11
                     /translation="MTDAIELDGITRTFGRTRALDAATFSLAPGLVHALLGPNGSGKTT
                     AIDVLTATRRPDAGRARVLGHDVRRGGPTASLVAVMPQALAFPEYLTVREVLALALVPH
                     AAALTPAAAIDRFDLDRLASRQTGGLSGGERRRVALACVVGAGTPVVVLDEPSAALDIP
                     GRAAVRDAIAAVRDSGRTVLLASHDMEEVAALADTVVCLDHGRVVGHWTAADFRGLAGV
                     RRVGFDATAAEARRLRSSGAVPEAGEEPRGLERIRWVIDTDRSDVVAGLVLAAVPQPRL
                     TVVEPGLGEIVERVLAGGAEAVPPDPSRTADAAGCAR"
     gene            complement(10001..11056)
                     /locus_tag="ITJ40_RS11460"
                     /old_locus_tag="ITJ40_11460"
     CDS             complement(10001..11056)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491342.1"
                     /locus_tag="ITJ40_RS11460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11460"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_194667198.1"
                     /sec_met_domain="PF00881 (E-value: 3.5e-19, bitscore: 64.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITDIGTAPTRTAPTRTAEDGPAGTGAEPGPAPAPASAGSVGPI
                     FSVGGAVERAAGDLAEDFHEASKITRITHPGWTDVRYAQQLAQEAQGVADAGPGGATSA
                     PRLLPALALPPALPLPHGLGATMAARRSADPDELAAPLALAELATVLRFAYGQRGGGTG
                     RFVPSAGGLYPLDLHVVVRAAEGVAAGIHQLDPLEEALVDVSGLDRAGRLARFRRAAPR
                     AMAPLAEQAAVTIVITGSFERSRTKYGLRGYRLTLLEAGHVAQNALLVATALGLPSIGW
                     VGFVDHELDAVLGLDGVTQSSLYAVSLGGRPDPGGTAPPGGLAPAAAHPDHPHAAAAGA
                     RHFAAEEASHD"
     gene            complement(11131..12402)
                     /locus_tag="ITJ40_RS11465"
                     /old_locus_tag="ITJ40_11465"
     CDS             complement(11131..12402)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491343.1"
                     /locus_tag="ITJ40_RS11465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11465"
                     /product="YcaO-like family protein"
                     /protein_id="WP_370532041.1"
                     /sec_met_domain="YcaO (E-value: 9.6e-52, bitscore: 171.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARLRTAGADVVSPFTGLVAYSHPMAFTPDAIPDALHSARTADTG
                     FLAGIATEGFSMGPGGSAADARRSCVGEAVERLSLAGGRGAFRAPLGSDARQVEPDAFR
                     RFHPAQREDPAFPFERAERGDLLTWLPARSLHGGRQLHVPAQMVVFDDPHASDGHRERH
                     LEPATSSGVAAGPTFGFAAGRAILELIERDAFQRAWLRASTPPAFDWRASPRLTEATRR
                     ELARLEELCGRFGAAFSLRVLDAAADVPVLLAVMRSERIGVAVGCAADFRLDRAVLNAV
                     REAVHTHNWCLRLLPQPPVEPSAVVEFEDHVRLHCAPSARPLSAALDASVESVASVGGP
                     SSWGEVVEGLHREGIDVLLSEITAPEVRAAGFHVVRALSPDLVALDVRHDARFLGHPRL
                     YRRWRDGPAIQSPADLVGVPHPFP"
     gene            complement(12390..13337)
                     /locus_tag="ITJ40_RS11470"
                     /old_locus_tag="ITJ40_11470"
     CDS             complement(12390..13337)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012297986.1"
                     /locus_tag="ITJ40_RS11470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11470"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_194667199.1"
                     /transl_table=11
                     /translation="MDPSTTYSVSPRYAVGEVEDTLHLLGGRELVSLQLPSGDAVSAVS
                     RLLSRPFTRADVDGAFGVHASVVADLVDELVVRDVVVGAPTRPAADAAPDPVGRLDDPD
                     QAELAHVLDEARRNGGDRTGIGRPRDPRTPARVALVGDAIPTLLTSLAEALPSAELTDE
                     TDADLVIAAGSRRVLREVGARMHAAGRDWLPIHPFDGRFQLVGPVVVPDEGPCLECVTL
                     RWASTTPFAADHAAVADAVAPVPRDPALDAIVAGFAARYAARWVFARDWLVASTVLVVE
                     PKVLSAEAHPVFRVARCGTCGPRPYAGVVSPWRA"
     gene            complement(13348..13572)
                     /locus_tag="ITJ40_RS11475"
                     /old_locus_tag="ITJ40_11475"
     CDS             complement(13348..13572)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039465.1"
                     /locus_tag="ITJ40_RS11475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11475"
                     /product="hypothetical protein"
                     /protein_id="WP_194667449.1"
                     /transl_table=11
                     /translation="MTLLMEGPASTGASALAEAPTRVEEVDAARADALLAEAFGFTITH
                     RGREAEVVMADVTLCCSTCCSCSSKQQPR"
     misc_feature    complement(13665..13679)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.52"
                     /tool="antismash"
     gene            13756..14418
                     /locus_tag="ITJ40_RS11480"
                     /old_locus_tag="ITJ40_11480"
     CDS             13756..14418
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039466.1"
                     /locus_tag="ITJ40_RS11480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11480"
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="WP_194667431.1"
                     /transl_table=11
                     /translation="MLAFPWEDDLAPAAPAPPPPPPHLTRIVAHSSDRVAWLRARSFGI
                     TATDVARLATDASLQAVALEKLYGSGFGGNRYTDHGREREPEIARWVESEHGIVPSAHL
                     FHAEGQRRHLATPDGVGLRADGRLELAEIKTTAKPWRSIPRNYLRQIWWQQYVLGAERS
                     LIVWEQHVDFVPVHDIPKWKWIDRDEAEIAALVARANDLIALIVRMANAPAGARGLA"
     gene            14679..15635
                     /locus_tag="ITJ40_RS11485"
                     /old_locus_tag="ITJ40_11485"
     CDS             14679..15635
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (26-313). E-value: 2.1e-39.
                     Score: 127.4. Matches aSDomain:
                     nrpspksdomains_ITJ40_RS11485_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012299881.1"
                     /locus_tag="ITJ40_RS11485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11485"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_194667432.1"
                     /sec_met_domain="ADH_N (E-value: 5.4e-07, bitscore: 24.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.4e-16, bitscore:
                     53.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAVVTETGGPDVLRMADIPVPRRLDSEVLVKVVAAGVNPVDLR
                     LRAGEPGGPTLGPLPAVLGRDFSGVVVESPYEDHALHPGDEVFGLAMAPRMPGSYAPYL
                     AVPSVSLARKPARLSHVEAAATPLSALTAWGMVVDIGRAHEGQVVLVHAGAGGVGHFAV
                     QFARHFGAHVIATGSPRNVEWLAELGADEVIDRTQARFEDVLADVDVVIDLVGNCTDDT
                     GTRSLAVLRRGGLIISAPVRGWPTLVQDAAAAGVRATHYEVAPDGQKLAVIARLLESGD
                     IKVYVDEVFDLQDAAEAHRHVEGGHARGKVVLNVARG"
     aSDomain        14757..15617
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ITJ40_RS11485_PKS_ER.1"
                     /evalue="2.10E-39"
                     /label="ITJ40_RS11485_PKS_ER.1"
                     /locus_tag="ITJ40_RS11485"
                     /protein_end="313"
                     /protein_start="26"
                     /score="127.4"
                     /tool="antismash"
                     /translation="DSEVLVKVVAAGVNPVDLRLRAGEPGGPTLGPLPAVLGRDFSGVV
                     VESPYEDHALHPGDEVFGLAMAPRMPGSYAPYLAVPSVSLARKPARLSHVEAAATPLSA
                     LTAWGMVVDIGRAHEGQVVLVHAGAGGVGHFAVQFARHFGAHVIATGSPRNVEWLAELG
                     ADEVIDRTQARFEDVLADVDVVIDLVGNCTDDTGTRSLAVLRRGGLIISAPVRGWPTLV
                     QDAAAAGVRATHYEVAPDGQKLAVIARLLESGDIKVYVDEVFDLQDAAEAHRHVEGGHA
                     RGKVVL"
     CDS_motif       15114..15176
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ITJ40_RS11485_0001"
                     /evalue="2.50E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="ITJ40_RS11485"
                     /protein_end="166"
                     /protein_start="145"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GQVVLVHAGAGGVGHFAVQFA"
     gene            complement(15662..16657)
                     /locus_tag="ITJ40_RS11490"
                     /old_locus_tag="ITJ40_11490"
     CDS             complement(15662..16657)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018763816.1"
                     /locus_tag="ITJ40_RS11490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11490"
                     /product="glycosyl hydrolase family 32"
                     /protein_id="WP_194667200.1"
                     /transl_table=11
                     /translation="MAFALPGHWVWDSWTAVDGGTTHLFYLHAPTSLGDPDLRHRNAAV
                     GHATSTDLVTWTDHGVVLEHGPAGAPDASATWTGSVTRDPSGLWRMSYTGSVFPRDDAG
                     VNVETVLQATSTDLHRWVKATGSALSADPRWYETLADGTWREEAWRDPWVEPDPAGGGW
                     RMLVTARSRMGAPGAGADPLDRGVVGQAVSPDLVTWTAAAPLSAPGAGFAQLEVLQVAT
                     VDGRRVLLFSCAASDLAGARAGEEGGIFALPLADEEPFGSAPLDIARAHLVHGAGLYAG
                     RIATTPAGDAVLMGFEDQDGDGRFGGRIPDPLPLAWDARGRLVVAGAPGR"
     gene            complement(16657..17481)
                     /locus_tag="ITJ40_RS11495"
                     /old_locus_tag="ITJ40_11495"
     CDS             complement(16657..17481)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /function="ABC-type sugar transport system permease
                     component"
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039470.1"
                     /locus_tag="ITJ40_RS11495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11495"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_012039470.1"
                     /transl_table=11
                     /translation="MIVNRTELVVGRILLIAVLVLTLLPFASMLTAALQSPDSLPNGFS
                     WPTPAYWENFVTAFTVGNIGTLMLSSLFIVVMVVPVSLVCATLAGYSLGNLRVPGGKYV
                     LVAMIIGLTIPFEAIIIPLYYQMTGFGLINTRWAVILPLIGLYMPFSVFWMRAHFVGVP
                     RELSEAARVDGASIWQEFRSIQLPLARPALSALGILLFLWTWNQFLLPLVMIDDPSERT
                     MAGALGAFQGQYIDALPLLFAASLIVMLPTVIVYVIFQRQFIAALLQGAVKG"
     gene            complement(17481..18473)
                     /locus_tag="ITJ40_RS11500"
                     /old_locus_tag="ITJ40_11500"
     CDS             complement(17481..18473)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039471.1"
                     /locus_tag="ITJ40_RS11500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11500"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_194667201.1"
                     /transl_table=11
                     /translation="MSTTDRTIPARATAPAAALAGPAPRRTGAARASGTRRRLGPEARR
                     TATVGWIMLLPAVAAYGTFVVWPLITAVQYSFYKWNGIGASTFIGLDNYVQIFTDTRLL
                     TPILNALILVVFFMVIPITAGLALATLLRGMKPGPFASISRTILFLPQIVPLVAAGIAW
                     SWMYAQSGTINSILDAVGLGFLSRSWLADFGTALPAVGLIGSWVLTGLCTVLLLTGMGK
                     IDGSLYEAVRLDGAGFFREFVTITLPGLRQEIAVLVTITVIAALSTFDIIYTTTKGGPG
                     TTTLVPGIEIFRLAFVQSQVGLASAFGVVLLVFVLLLVLPVQRLSRERD"
     gene            complement(18470..19819)
                     /locus_tag="ITJ40_RS11505"
                     /old_locus_tag="ITJ40_11505"
     CDS             complement(18470..19819)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039472.1"
                     /locus_tag="ITJ40_RS11505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11505"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_194667202.1"
                     /transl_table=11
                     /translation="MSTMRRAGRAAALTAAAAISALALASCAPGSAPVASAPSGAVSTA
                     IPTDDVTIRIQDETGFPVTDELTAEFTKQHPNVKFDITRDSFQNLLANTPRLLASDDAP
                     DLIRLSTLGTTVKDGLLTNLDPYFDAYGWDRFPAGQLAGARMDDQGVRGEGSLWQFGIG
                     YSVTGIYMNQKLADQVGITEMPSTMDELEADLAKAKDAGVLPIQTGMQDGVGTFILQSL
                     INQQGDKQGLVDWMYNKPGATIQTDAALAGATQFQDWAKAGYLPPDVNAINYTTMVSNF
                     SAGQGLFMWDGNWDAANVEKALGTGGAQFALVPPLEAGAKHVAMGTGNTFAIPAKSKNA
                     DVVAAFLNWIVTDEKARQIVVDVTGASPGGDPAQALPTAKEGSLIAKALELSAVVGGDD
                     GFVDFMANSTAGIYQGSLQPNEQLLLTDKMAPADFLKATQDFYEQDLAAQ"
     gene            20035..21120
                     /locus_tag="ITJ40_RS11510"
                     /old_locus_tag="ITJ40_11510"
     CDS             20035..21120
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039473.1"
                     /locus_tag="ITJ40_RS11510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11510"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_194667203.1"
                     /transl_table=11
                     /translation="MRQKRPTLADVARLAGLSPTAASQILNGTPATRFSEDAHRRVLAA
                     SAELGYRPNMGARALRTDRSLTIGFISDVVATTRFASGLIRGALVEAERAGHVVLVLET
                     GDEEARAAEAVSAVLDRQVDGIVFATMRARELVVPDVPASTPVVMLNATSPHHARSVLP
                     DEEEGGRRAVDLLAAAGHVDGIALLGSDPETERRLFRSETVARRLHGIRGEMAELGLGF
                     TAERACADWEPETGYEAAGAMLDAAPGIRAMICLNDRLAFGAYQACQERGVRVGAEMSL
                     VGFDNDELASYLRPGLTTIALPHEEMGCEAVRLVLRDAEPGERLVGMPVVERGSIATAS
                     PADGGPAVVARERLATPAETA"
     gene            complement(21143..21742)
                     /locus_tag="ITJ40_RS11515"
                     /old_locus_tag="ITJ40_11515"
     CDS             complement(21143..21742)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039474.1"
                     /locus_tag="ITJ40_RS11515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_11515"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_194667204.1"
                     /transl_table=11
                     /translation="MSIPDPAVTPAVPVFRVATAADADGVAALAARTFALACPPTTTAR
                     AIAEHIRTVLSSARFRAHLADPACRVVLAEVDGRPVGYTMVVAAPPTDADVTGALRLRP
                     EVEVSKVYVEQGSHGAGVARPLMTETLRVARELAGERGRDADAGIWLGVNEHNARAIRF
                     YERSGFRIVGTRSFRLPDAVETDHVMERPLAAAAAG"
ORIGIN
        1 cacgccggcg acctcgaccg acagcgtgta ggtcgcgccg cccgcgggca cggccggacg
       61 ctgcttctcc tggcacgtgg tggtggacga ccgctggcgc gaccactcga acggcgacga
      121 cgtctgcggc gtgcgggcgg cgagctcgac ctcggcgtcc gccgcgcccg tctggcagtc
      181 ggtggacttc cagtacacgt cggatccgct cgagatcgtg aagacctgcg tggtcgtccc
      241 gaggttcgca gtgcagggct ccatgcccgt gttcgtcacg gtgaaggaga gcttgggcag
      301 cacgcccgcc ttgtaggagg cggcgtcggt gacgggggtg acggtcagct ggcccgcggc
      361 gcaggatccg tcggcgttcg tctccgtgcc ggcgctcgcg ctcgggctgg ggtcgggggc
      421 cggtgcggtc tcggcggcgg cgtcgcccga gtcgccgtcc ggggcggcgt ccgcgctggg
      481 cgtcgcgccg ggtgccgcgg tgtcggccga gccgcgcccg aggttggaga cgaggatcac
      541 gacgaccgcg atcacggcca ccacgacgag cagcgccatc aggcggcgac gacggtacac
      601 ggccgcggac gggcggcctt cgggcgaggt cgaggacatg agcacaggct attcgcggcc
      661 ccggccgcgg cccggtcggc gcgcccgggg agcccggcgc cggatcccgc gcatcccgct
      721 ggcccgtccg ccgccgcgga cgcgacggcc tcggctcaga gcgccttcag catgcgcgtg
      781 ttgccgagcg tgttcggctt gacgcgggag aggtcgagga actcggcgat gccctcgtcg
      841 tgcgagcgga gcatctcgta gtagatctcc tgcgcgatga tcgactccgc cacctcgtgg
      901 tagccgtgcc gcgagaagaa gccgacctcg aaggtcaggc agaacaggcg gctgaggccg
      961 agctcgcggg cgtcgtcctc gaggcgctcg agcagcgcgt ggccgacacc ggtgccgcgg
     1021 gtgtgcgggg cggctgcgag ggtgcggatc tcgccgaggt cctcccacat cacgtgcagc
     1081 gcgccgcagc cgacgacctc gccggacgcg tcgaccgcga cccggaactc ctgcacgttc
     1141 tcgtagagca ccacgaggtc cttgccgagg aggatcccct ccatcacgag cggctcgacg
     1201 agctgctgga tccgcggcac gtcgccggtg cgcgcgcgtc gcacgcggat gccgcctgcg
     1261 ggctccgcgg actcgacgac gactggctct gcgctcacga tgacgaccct ctcgatccgc
     1321 ggctcgggcg cccggatcag gggtccagcc tagcgacggg cggatcccgc gtccggggcc
     1381 ggcggctcgg cgccggtgtc gctgccgccg ccgagccgcg cgatcatccg cggcgcgatc
     1441 cacacgatcg ccaccacgcc gaccaccgcg cgcagccccg cgaagacgag cacccaccag
     1501 ccgaccccgt cgccgcccac gagcagcgcg accccgatga cgacgagcgc cgcgtccgcg
     1561 acgaacggca cgcgcagcca gaacatgagg cggcggacgg gatccatggc tcaaccggcc
     1621 gcgcgcgggc tcggccggtc ggccacggga tcccccgacg gcggcgccca gcggtcggac
     1681 gcggcgggag cctcgggacg cgcatccccc gcccgccgct ccagcggcag ccgcacgccg
     1741 aacaccgtgc ggcccggctc cgactccacc cacaccgcgc cgtggtgcgc ggacacgatc
     1801 gcctgcgcga tcgcgaggcc gaggcccgtg ccgccggtgg agcgggcgcg ggatccgtcg
     1861 ccgcgcacga agcgctcgaa cagcgaggcc tgcagctccg gcgggatgcc ggggccgtcg
     1921 tcggtgacgc ggatgaccgc gtgcccgtcg gatccggtgc cctccaccgc cagcgacgcg
     1981 acgacgcgcg tcccggccgg cgtgtgcgtg cgggcgttcg cgagcaggtt gacgaccacc
     2041 tggcggagcc gggcgtcgtc gccggggacg gtcacggagt cgtcggggag gtcgaggtcc
     2101 cagtcgtgat ccgggcccgc cgcgctggcg tcgccgaccg tgtcgaggag gatgcgcgtg
     2161 aggtcgaccg gatccgtctc cagctcgcgt ccctcgtcga ggcgcgccag gagcagcagg
     2221 tcctcgacga tcgtggtcat gcgcaccgac tccgactcga tgcgcgacag cgagtgcgtc
     2281 acgtcctcgg gcagccggtg cgggccgcgc cgggtgagct cggcgtagcc gcggatggag
     2341 gcgagcggcg tgcgcagctc gtggctcgcg tccgacacga accgccgcac cttcgcctcg
     2401 ctcgcctgcc gcgacgacag cgcggcggag acgtgcccga gcaggccgtt gagcgcggcg
     2461 cccacgcggc ccacctcggt gcgctcgtcg gtgtcggatg cgggcacgcg cgcctcgagc
     2521 gcgacgtcgc cgcggtcgag ctcgagcgcg gccacgtggg tcgccgtgtc gacgacccgg
     2581 tcgagcggac gcagcgcgcg gcgcacgatg acggcaccga gcaccgcggc gagcgccagc
     2641 gtgagggcgg cgaccacgga gatcacgacg atgagctgct ccaccacgtc gtcggcgggc
     2701 ttcatcggca ggccggtgac gagggtcgcg cccgtggcgg cggtgtcgcc gaccagacgg
     2761 tagcggccga gcgcgccgcc gaggtcgacc gtgcggggga tcccgtcggt gggcacgctc
     2821 tgcagctgct ggctctgcac ctgcgtcagc tccaccgcgc ccgcgccgcc cggctcgccc
     2881 tcggccgcgt cgcggtcggc gatgtacccg cccgagacca cgccgtcgac gatggtcgcg
     2941 ctgatcgtgc cgacctgctg cccgaaggca ccgagcccgc cgggaggggc gccggggaag
     3001 ctcccgtact ggtccgcgtc ccggtcgatg aggttcgagg agcgcgccgc ggtcgcctgc
     3061 agctgctggt cgacctgctg cacgagcgac gcccgcagcg cgaggatgct gaccgtgccg
     3121 atgaggatgc tcgcgagcgc cagcagcccc accacgctga gcacgaggcg gcgccgcagc
     3181 gtcatgccgc gcgcggcggc ggtgagccgg gcccgcagcg gcggggtgcc cgacggcttc
     3241 gtcactccgc ggccttgagc atgtagccgc tgccgcgcac cgtgtggatc atggggttcc
     3301 ggccggcgtc gatcttgcgg cgcaggtagg agatgtagat ctcgaccacg ctcgacttgc
     3361 ccccgaagtc gtagctccac acccggtcga ggatctgcag cttgctcagc acgcggcgcg
     3421 ggttgcgcat caggtagcgc agcagctcga actcggtggc ggtgagctcg atggggtcgc
     3481 cggcgcgcgc gacctcgtgg ctgtcctcgt cgagggtgag gtcgccgacg cggatcaccg
     3541 ggtcgacgct gtcgctcacc acgagcgtcg agcggcggat gaggccgcgc agccgggcca
     3601 cgacctcctc caggctgaac ggcttggtga cgtagtcgtc gccgcccgcg gtcagcccgg
     3661 cgagccggtc gtcgagcgag tccttcgccg tgaggaagag cacggggatg tcctcggcgt
     3721 ccgctcgcag ccgcgacagg acctggaggc cgtcgaggtc cggcagcatg atgtcgagca
     3781 ccacggcgtc gggcttgaac tcgcgcgcgg cggcgagcgc ctggtgcccg ttctcggccg
     3841 tgcggatctg ccagccctcg tagcgcagcg ccatctggag caggtcggtg agggacgcct
     3901 cgtcgtcgac gacgagcacc cggatgggcg acccgtcggc gcgcgtgagg cggggctgcg
     3961 gggcggcggc gggctggaag ccggagggcg gggtggtggt cacgggatcc atcatgcgga
     4021 tgttcctatg aagcgcccat gagccggcca tgcgcgggct tcagcggaca gtgcgagggc
     4081 gggcctcaga acgggagggg atcgccgacc cggaggccca tgctgacgag cgcggcgacc
     4141 acgaggccga gcaggatcgc gccgctgatc cacgggagca cgtcgacgtc gatggggtcg
     4201 ctgtccggtt cccgctggcg ccgacgccgc tcatccacgc gcatcacgta ggcgtgcgcg
     4261 acgcaggcgg cggccatcgt cccgagcgtg gcggtgcccg tccagcgggc gagcgccgtg
     4321 accggctgac cgcacagcgc agccacccac acgaccacgg cgcccagggc gaagacgatc
     4381 ccgatgagcc accatgcgaa gcctgccgcg acctccacga cctcgtaggc gaaggaggac
     4441 ggggtgctcg cgtagcgcgc cgccttccgc tcgcgcttcg tcatgcgcgc cgggtcggcg
     4501 aagtcggcgc gatggagatc gatcgcgggc gtcagcgcgc gcacctccgc gggcagatcg
     4561 gcgtcgggcg gcagccccag gaaagcaggg atctcgtggt ccgcgatccc ggagtgcgcg
     4621 atcatgcgcg ccaggcggtc gcgctccacc tccgtggtcc agccggggga cgcgatgccc
     4681 catcggccgg cctggtcggg cgcgatgagc tcgcggtaca gcccggcgag ggcgagccgg
     4741 gcgccggtgt cgaggggctc atcccggagg tgctccttga ggagggcgag ggcctcggcc
     4801 cggtcgccct cgtcccacag gaggccggct cgggtcgggg cgtcgggggc gtcgggggcg
     4861 tcgggcaccg gccgatgctg ccaggtcggc gggcgcggcg agcgggcagc gcacggtcgg
     4921 ccggccggtg tccgcccgcg gacgacgacg gacccggcgc gtgatgcgcc gggcccgtcg
     4981 tcatgcggat cgcgcggagg ctagtgcttc tcctccgtcg cgcgcgtgac ggtctcgccg
     5041 tcgacgctcg cgcggtcctc cttctgcttg tcgccgcggg tcttcgcgag gctcgcgacc
     5101 gtggcgaccg tgatggtcgc gccgatgaag aggagcgaga accagatggg gatctcggga
     5161 gcccacagca tcggctggcc gccgttgatg aagggcagct cgttgacgtg catcgcgtgc
     5221 agcacgagct tcaggccgat gaacgcgagg atgaccgcga ggccctgcga caggtagacg
     5281 aggcgctcga gcagcccgcc gatgaggaag tacagctggc ggaggcccat cagcgcgaag
     5341 gcgttcgcgg tgaacacgat gtacgcctcg ttcgtcaggc cgtagatggc cgggatcgag
     5401 tcgagcgcga acaccaggtc gacgaagccg atcgcgatga cgcagagcag cagcggggtg
     5461 acgaagcgct tgccgtcgat cttcgtggtg aagcggtcgc cgacgaagtc gtcgtggacg
     5521 ggcaggatcc ggcgggcgat gcgcacgaac aggttgtccg ccgcgttgcc gccgtggtcg
     5581 cccttcagct gctggtacgc gagcacgaac agcagcgcgc cgaagatgta gaagacccag
     5641 gagaagttct cgatgagcgc ggcgccgagg gcgatgaagc cggcgcgcat gatgagtgcg
     5701 atgacgatgc cgatcatcag caccttctgc tggtacttcc gcggcacggc gaacccggtc
     5761 atgatcagca ggaacacgaa caggttgtcg atcgacagcg ccttctcggt gaggtagccg
     5821 gcgaagtact cgccaccgta gccccagccg ctggtgaagc cgatgccgac gccgaagatc
     5881 agtgcgaggc cgatgtagaa ggccgaccag cgggcggact cgccgatggt gggctcgtgg
     5941 ggcttccgca cgtgggtgaa gaactcgtag acgaagaacg cgatggtgac cgcgatcgtg
     6001 atgagccagg tggtcgtggt gatgttcacg ggggtctccg ggaatgaggc cgacgggata
     6061 tcgggacggc gggtggcgcg gatccccatg atcccatgcg gcatctcccc ataccgggga
     6121 aatgcctgcg cctacgctcc gtggatcgtg cggctccggc cggctcaggt caggctcggc
     6181 gcctcgaacg gataggcgac gtacgcgaac cggcgggagt cgggcgccca gctggtgacg
     6241 ttgatggtgc cctggccgcc ggggaaggtg gcgaggtcgc gggtgcgatg gctctgccgg
     6301 tcgatgacgc ggaggatcac gtcgtggtcg gcggggtggc cgagcgtgcc gggcgggaac
     6361 gagaggtaga cgatgtgctc gccgtcggga gacgggtgcg ggaaccagtt gacgcgctcg
     6421 tcggaggtga actggtgcgt gtcggtgccg tcgacgcgca tcgtgaacag ttgcgcgtgg
     6481 cccggcagat cggatccgcg ctccgagttg aagtagagcc agccgccgtc gggcgagaac
     6541 tcggcgccgt cgtcggggaa gccgtcgtcg gtgagctgcg tggtggggcc gccgtcgacg
     6601 ggcacgaggt ggatgttcgt ggtccactcg ccgcgcgcgt cgacctgccc gccgatgacg
     6661 ctgagcgtcg agccgtcggg cgagacgccg tgcaggtagt tcttgaagcg gagcgccgga
     6721 tcccggtccg ccgtgatccg acgcccctgc ccacccgcgc cgtcgttcca gagcacgtcg
     6781 tacaggtgac cgtcgcggcc ggagacgtac acgtgcgcgc cgtcgggcga gaagacgtgg
     6841 tcgttgttga tgggcgggac gccgccgaga tccaccgcct ggaagtcgac cgcgggctcg
     6901 ggcaggtccg gatccggctc ctcggcctcg ggcgcgcgca gccgccagag cccgccctcc
     6961 gcgttcacga cgagccagcg tccgtcgggc gtccagttcg gcgcctcgat gtgcagcacg
     7021 gccgactcgg cgaccatgcg ctcggcgccc gtctccacgt cgacgacgag gaggcgggcc
     7081 agctggccgt cgcgcagcgt cacgcggtgg atccggcggt gccgtcggcg ggcgtcgcgg
     7141 cgggcgcgtc gtcccggttg ttcgcgaacg ccgagtcgaa caggctgtcg ggcgtcggcc
     7201 agaggaggga gcgcacctgc gcgagggcgt cgggggctcc gtgcaggcga tccatccccg
     7261 catcctccca ctcgacggac acgggtccgt cgtagccgat gctgcggagc gcccggaagg
     7321 cgcgctcgaa cgggacgtcg ccgtggccga ccgagacgaa gtcccagccg cggcgcgggt
     7381 ggccccacgg gaggtgggat ccgagccggc cgccgcggcc gtccgaggtg acccgtgtgt
     7441 ccttggcgtg cacgtggtag atccggtcgg cgaagtcgag gaggaagccg acggggtcga
     7501 tgccctgcca catcatgtgg ctcgggtccc agttcaggcc gaagccgggc cggtggccga
     7561 tcgcctcgag cgtgcggcgg gtggtccagt ggtcgtaggc gatctcgctc gggtgcacct
     7621 cgagcgcgta ccgcacgccc tcgtcgtcga acacgtcgat gatcgggttc caccggtcgg
     7681 cgaagtcctg gtagccggcg tcgatgaccg attcgggcac gggcgggaac atggcgacgt
     7741 agggccagat gcgggatccg gtgaagcccg tcacgcgcgt caccccgagc ccggcggccg
     7801 ccttcgcggt cagcttcagc tcctcggccg cgcgctgacg gacgccctcc gcctggccgt
     7861 cgccccacac cttggagcgg aggatcgcct ggtgccggaa gtcgatgggg tcgtcgcaca
     7921 cggcctggcc ggtgaggtgc tgcgagagcg cgtgcacccg gaggccgtgg cgctcgagga
     7981 tctccaggcg gccgcggagg tacgccggat cctccgccgc gcgccacacg tcgaggtgct
     8041 ccgcggagca cgcgatctcg agggcgtcga agccccagcc gctcgcgagc cgggcgacct
     8101 cctccagcgg caggtcggcc cactggccgg tgaagagcgc tacgggcgtg gtgatctggg
     8161 gcatggttcc ctctcgtcga cggtgacggt gcggtgcgtg cggtggcgcg gcccggtgac
     8221 ggcgcgcggg atccacgcta cacaccgggc cgcgcccgct cgcggggctc cgtcagcgaa
     8281 agttcgccga ctgcgtgcgc tggtacccgg cgagcgtgat gccgccgagg agcaccgccc
     8341 aggccgcgag gaggatcagc gggatgccca tcgtcgcggt gtcgtgccgg gcggcggcgc
     8401 tcgtcagcgt gctccacgcg ccggtgggga gcaggaccgt gagcgactcc cagggcgtgc
     8461 cgctcgtgtc cccgcccgtg aacagcccgc ccgcgaacga cagcggcagg tacacgaggt
     8521 tcgcgaggcc gagcgcgccc cgggcgggga accagtagcc catcgccagt ccgagcagcg
     8581 ccatcgggac ggcgccggcc agcacggcga gcgcgacggc tgcgagggtc gccgcgtcga
     8641 cccgcacccc gccgaccgtg aacccgacga gggcgacggg gatcacgaac agcaccccga
     8701 agacgcacgc gaccgtgagc ttggcggcga gccggatcca cgcgggcacc ggcgccgtga
     8761 acagccaccg ctcccacggc gactcccggg ccgacgcgac gccgacgccg aactggaagg
     8821 tgacggtgcc gagcaccgag aacagcacgt agccgaggag cacgctgagc cgcgcgctcg
     8881 gcgggccgcc ctgcggcagg ccgacgacga cgtagatgag cacggggtag gcgaggagcg
     8941 gcagcacgaa cgccggcatg cgcgcgttct gcgcgagctc gctcacgacg tgggcgcggt
     9001 agatcgccag ccggcgcgcg gcggtgggac gggcgggcat cagcatggcg ctcatcgggc
     9061 gcatcccgcc gcatccgcgg tgcgtgacgg atcgggcggg acggcctccg cgccacccgc
     9121 cagcacgcgc tccacgatct cgccgagccc cggctcgacg accgtgaggc ggggctgcgg
     9181 gacggcggcg agcaccagcc cggcgacgac gtcggagcgg tccgtgtcga tgacccaccg
     9241 gatccgttcg aggccgcgcg gctcctcccc cgcctcgggc accgcgccgg acgaccggag
     9301 gcgccgcgcc tcggcggcgg tcgcgtcgaa gccgacccgc cgcacgccgg ccagtccgcg
     9361 gaagtcggcg gcggtccagt ggccgacgac ccggccgtgg tcgaggcaga cgaccgtgtc
     9421 ggcgagcgcc gcgacctcct ccatgtcgtg cgacgcgagg agcaccgtgc gcccggagtc
     9481 gcggaccgcg gcgatggcgt cgcgcaccgc ggcccggccg gggatgtcga gcgccgccga
     9541 cggctcgtcg agcacgacga cgggcgtccc cgcaccgacc acgcacgcga gcgcgacccg
     9601 ccgtcgctcg ccgccgctga gcccgccggt ctggcgcgac gcgaggcggt cgaggtcgaa
     9661 ccggtcgatg gcggcggccg gagtgagcgc ggcggcatgc ggcacgagcg cgagcgcgag
     9721 cacctcgcgc accgtgaggt actcggggaa cgcgagcgcc tgcggcatca ccgcgacgag
     9781 cgaggccgtc gggccgccgc gacgcacgtc gtggccgagc acgcgcgcgc ggcccgcatc
     9841 cggccgccgg gtcgccgtga ggacgtcgat ggccgtggtc ttgccggatc cgttcggccc
     9901 gagcagcgcg tgcacgagcc ccggcgcgag ggagaacgtc gcggcgtcga gggcgcgcgt
     9961 gcggccgaag gtgcgggtga tcccgtcgag ctcgatcgcg tcagtcatgg gatgcctcct
    10021 ccgcggcgaa gtgccgcgcg ccggcggccg ccgcgtgcgg gtggtcggga tgcgccgcgg
    10081 cgggagcgag cccgcccggg ggcgcggtgc caccgggatc cggacgccca cccagcgaga
    10141 ccgcgtagag cgacgactgc gtcaccccgt cgagcccgag cacggcgtcg agctcgtggt
    10201 cgacgaagcc gacccagccg atcgacggca gcccgagcgc cgtcgcgacg agcagcgcgt
    10261 tctgcgcgac gtgccccgcc tcgagcagcg tgagccggta gccgcgcagc ccgtacttgg
    10321 tgcgggagcg ctcgaagctg ccggtgatca cgatcgtcac ggccgcctgc tccgcgaggg
    10381 gcgccatggc cctcggcgcg gcacgccgga agcgcgcgag ccgaccggcc cggtcgaggc
    10441 cggacacgtc gacgagcgcc tcctcgagcg ggtcgagctg gtggatcccc gccgcgacgc
    10501 cctccgccgc ccgcaccacg acgtgcaggt cgagcgggta gagcccgccg gccgagggca
    10561 cgaagcggcc ggtgccgccg ccgcgctgac cgtaggcgaa ccgcagcacg gtcgcgagct
    10621 ccgcgagcgc gagcggcgcg gcgagctcgt ccggatccgc ggaccgccgg gccgccatcg
    10681 tcgccccgag cccgtgcggc agcggcagcg ccggaggcag ggcgagcgcc gggagcaggc
    10741 gcggcgcgct cgtggcgccg cccggtcccg cgtccgcgac gccctgcgcc tcctgcgcca
    10801 gctgctgcgc gtaccgcacg tcggtccagc cggggtgggt gatgcgcgtg atcttggacg
    10861 cctcgtggaa gtcctcggcg aggtcgcccg ccgcccgctc gaccgcgccg ccgacgctga
    10921 agatcgggcc gacgctgccg gcggacgccg gtgccggtgc cggaccgggc tccgcacccg
    10981 tcccggcggg gccgtcctcc gccgtgcgcg tgggcgccgt gcgcgtgggt gcggtgccga
    11041 tgtcggtgat gctcatgggg tcctcctggt ggtgcgggcg cgacgggtcg cgatgacgtg
    11101 gacgcggggc ggcggggcgg cggtgcgtcc tcacgggaac gggtgcggga cgccgacgag
    11161 gtcggccggg ctctggatcg cgggcccgtc ccgccacctc cggtacaggc gcggatgacc
    11221 gaggaaccgg gcgtcgtgcc gcacgtcgag ggcgaccagg tcggggctca gcgcgcggac
    11281 gacgtggaag cccgcggcgc gcacctccgg cgcggtgatc tcggacagca gaacatcgat
    11341 cccctcccga tgcagcccct ccacgacctc tccccagctc gacggcccac ccacggacgc
    11401 cacggactcg accgacgcgt cgagggcggc ggacagcggg cgggcggacg gcgcgcagtg
    11461 cagccgcacg tggtcctcga actcgacgac cgcggacggc tcgacgggcg gctggggcag
    11521 caggcgcagg caccagttgt gggtgtgcac cgcctcgcgc acggcgttga gcacggcgcg
    11581 gtcgagccgg aagtcggccg cgcagcccac cgcgacgccg atgcgctcgc tccgcatcac
    11641 cgcgaggagc acgggcacgt cggccgcggc gtcgagcacg cgcagcgaga atgcggcgcc
    11701 gaaccgcccg cagagctcct cgagccgcgc gagctcgcgc cgggtcgcct cggtgaggcg
    11761 ggggctggcg cgccagtcga aggcgggcgg cgtggacgcg cgcagccacg cccgctggaa
    11821 cgcgtcgcgc tcgatgagct cgaggatcgc ccgacccgcc gcgaagccga acgtgggccc
    11881 ggcggcgacg ccggacgagg tggccggttc gaggtgccgc tcgcggtggc cgtcggacgc
    11941 gtgcgggtcg tcgaagacca ccatctgcgc ggggacgtgc agctgcctcc cgccgtgcag
    12001 cgaccgcgcg gggagccagg tgagcaggtc gccccgctcg gcgcgctcga acgggaacgc
    12061 cggatcctcg cgctgcgccg ggtggaagcg ccggaacgcg tccggctcga cctggcgggc
    12121 gtcggagccc agcggcgcgc ggaacgctcc ccggccgccg gccagggaga ggcgctccac
    12181 cgcctcgccc acgcacgacc tccgggcgtc cgctgcgctg ccgcccggcc ccatgctgaa
    12241 cccctcggtg gcgattcccg cgaggaagcc cgtgtcggcc gtgcgtgcgg agtgcagcgc
    12301 gtcggggatg gcgtccggcg tgaacgccat ggggtgcgag tacgcgacga gcccggtgaa
    12361 cgggctcacc acgtcggccc ccgccgtcct caggcgcgcc acggcgacac cacccccgcg
    12421 tacggccgcg gcccgcaggt gccgcagcgg gcgacgcgga agaccggatg cgcctcggcc
    12481 gacagcacct tcggctcgac cacgagcacg gtgctcgcca ccagccagtc gcgcgcgaag
    12541 acccagcggg cggcgtaccg cgcggcgaag ccggccacga tggcgtcgag cgcggggtcg
    12601 cgggggacgg gcgcgacggc atcggcgacc gccgcgtgat ccgcggcgaa gggcgtggtc
    12661 gaggcccagc gcagggtgac gcactcgagg cacggcccct catccggcac gacgaccggg
    12721 ccgacgagct ggaagcggcc gtcgaacggg tggatgggga gccagtcgcg accggccgcg
    12781 tgcattcgcg cgcccacctc ccggaggacg cgtcggctgc ccgccgcgat gaccaggtcg
    12841 gcgtcggtct cgtccgtgag ctccgccgag ggcagcgcct cggccaggga ggtgagcagg
    12901 gtcgggatgg catcgccgac cagggcgacc cgcgcggggg tgcggggatc ccgagggcgg
    12961 ccgatgcccg tgcggtcgcc gccgttgcgc cgcgcctcgt cgagcacgtg cgcgagctcg
    13021 gcctggtcgg ggtcgtcgag gcggcccacg ggatcgggcg cggcgtcggc ggcgggccgc
    13081 gtgggcgcgc ccacgacgac gtcgcgcacc accagctcgt cgacgaggtc ggccacgacc
    13141 gacgcgtgca cgccgaacgc gccgtcgacg tcggcgcgcg tgaagggacg ggagaggagc
    13201 cgcgacaccg cggagacggc gtcgccggag ggcagctgta gggagaccag ctcgcgaccg
    13261 ccgaggaggt ggagggtgtc ctccacctcc ccgacggcgt agcggggact caccgagtag
    13321 gtcgtcgacg ggtccatgac ggatgcgtca gcgaggctgc tgcttgctgc tgcacgagca
    13381 gcacgtgctg cagcagaggg tgacgtcggc catcacgacc tccgcctccc gcccgcggtg
    13441 cgtgatggtg aagccgaacg cctcggcgag cagcgcgtcg gcgcgcgcgg cgtcgacctc
    13501 ctcgacgcgc gtgggcgcct ccgcgagcgc cgatgctccc gtgctggccg gtccttccat
    13561 gagcagggtc atgccgtttc ctctctccgt gctggtgatg ggtgggtggg acgacgcctt
    13621 tctagcacga tcttccgtgc cctgggcaga tgcgcattac ctgttgacaa cgacgtcctg
    13681 agcccggagc attcgcccgc gtcgaggcgg cccgggtcgg atccgacgcg taccctggag
    13741 cccgtgacgg acgagatgct ggccttcccc tgggaggacg acctcgcccc cgccgcaccc
    13801 gcgccgcccc ctcccccgcc gcacctgacg cgcatcgtcg cccactcctc ggatcgcgtc
    13861 gcctggctcc gcgcccgcag cttcggcatc accgcgaccg acgtggcgcg cctcgcgacc
    13921 gacgcctcgc tgcaggccgt cgcgctcgag aagctctacg gatccggctt cggcggcaat
    13981 cgctacaccg accacggccg cgagcgcgag cccgagatcg cccgctgggt cgagtccgag
    14041 cacggcatcg tgccgagcgc gcacctgttc cacgccgagg gccagcgccg gcacctcgcg
    14101 acccccgacg gcgtgggcct gcgcgccgac ggccgcctcg agctcgcgga gatcaagacc
    14161 accgcgaagc cgtggcgcag catcccgcgc aactacctgc ggcagatctg gtggcagcag
    14221 tacgtgctcg gcgccgagcg ctcgctcatc gtctgggagc agcacgtcga cttcgtgccc
    14281 gtgcacgaca tcccgaagtg gaagtggatc gaccgggacg aggccgagat cgccgcgctc
    14341 gtggcgcgcg cgaacgacct catcgcgctc atcgtgcgca tggcgaacgc gccggcggga
    14401 gcccgcggcc tggcctgatc cgccggcagg cgcggcacgg cccggcgacg gcgccggtcc
    14461 cgcgcattct tctcacccgg ggaacaccgc ggaaacacgc ccgactcacg cgccgacttc
    14521 actggtggtg cgggggcgcg gtgggatccg ccgcaccgtc acgtcggagg aggggtcgca
    14581 cgatgagcca ggtcgtccag tcgagagccg gcgtcgccgc ccaggcccag cgggatcgcg
    14641 cggccgcgtc cctcgcgctc gcgccgcacg gcaccaccat gcgcgccgcc gtcgtgacgg
    14701 agacgggcgg gccggacgtg ctgcggatgg ccgacatccc cgtgccgcgt cgcctcgact
    14761 ccgaggtgct cgtgaaggtc gtggccgcgg gagtgaaccc ggtcgacctc cggctccgcg
    14821 ccggcgagcc cggcggcccg acgctcggcc cgctgccggc ggtgctcggg cgcgacttca
    14881 gcggcgtcgt cgtcgagtcg ccctacgagg accacgcgct gcatccgggc gacgaggtgt
    14941 tcggcctcgc gatggcgccg cggatgcccg gcagctacgc cccctacctc gccgtcccca
    15001 gcgtcagcct cgcccgcaag cccgcgcgcc tgtcgcacgt ggaggccgcg gcgacgcccc
    15061 tcagcgcgct gaccgcgtgg ggcatggtcg tcgacatcgg acgggcgcac gagggccagg
    15121 tcgtgctggt gcacgcgggg gccggcggcg tgggccactt cgcggtgcag ttcgcgcggc
    15181 acttcggcgc gcacgtgatc gccaccggct cgccgcggaa cgtcgagtgg ctggcggagc
    15241 tcggggcgga cgaggtcatc gaccgcacgc aggcgcgctt cgaggacgtg ctcgcggacg
    15301 tcgacgtggt gatcgacctg gtcggcaact gcacggacga caccggcacg cgctcgctcg
    15361 cggtgctccg ccgcgggggg ctgatcatca gcgctcccgt gcgcggctgg ccgacgctcg
    15421 tgcaggacgc cgccgccgcg ggcgtgcgcg ccacccacta cgaggtcgcg cccgacgggc
    15481 agaagctggc ggtcatcgcg cggctgctcg agtcgggcga catcaaggtc tacgtcgacg
    15541 aggtcttcga cctgcaggac gccgcggagg cgcaccgcca cgtggagggc gggcacgcgc
    15601 gcggcaaggt cgtgctcaac gtggcgcgcg gctgatccgc ggggccggta cgcgccgccc
    15661 gtcagcggcc cggggcgccg gcgacgacga gccgcccccg ggcgtcccac gcgagcggga
    15721 gcggatccgg gatccgaccg ccgaagcgcc cgtcgccgtc ctggtcctcg aagcccatca
    15781 ggacggcatc gcccgccggc gtcgtcgcga tccgccccgc gtacagcccg gcgccgtgca
    15841 cgaggtgcgc ccgcgcgatg tcgaggggcg cggatccgaa cggctcctcg tcggcgagcg
    15901 gcagcgcgaa gatcccgccc tcctcgccgg cccgggcacc ggcgaggtcc gacgcggcgc
    15961 acgagaagag gaggacgcga cgcccgtcga ccgtcgcgac ctgcagcacc tcgagctgcg
    16021 cgaacccggc gccgggcgcg ctgagcggcg cggcggccgt ccacgtcacg aggtcgggcg
    16081 agaccgcctg ccccacgacg ccgcggtcga gcggatcggc tccggcgccg ggcgcgccca
    16141 tgcgggacct cgcggtgacg agcatgcgcc agccgccgcc cgcgggatcc ggctcgaccc
    16201 agggatcccg ccacgcctcc tcgcgccagg tgccgtcggc gagcgtctcg taccagcgtg
    16261 ggtcggccga caacgcggat cctgtcgcct tcacccaccg gtgcaggtcg gtcgaggtcg
    16321 cctgcagcac ggtctccacg ttcacgcccg cgtcgtcccg cgggaacacc gagcccgtgt
    16381 acgacatccg ccagaggccc gacgggtcgc gcgtcacgct gcccgtccac gtggccgacg
    16441 cgtccggcgc gccggccggg ccgtgctcga gcacgacgcc gtggtcggtc cacgtgacga
    16501 ggtcggtcga ggtcgcgtgg cccacggcgg cgttgcggtg ccggaggtcc ggatccccga
    16561 gcgaggtcgg cgcgtgcagg tagaagagat gcgtggtgcc gccgtcgacg gccgtccacg
    16621 agtcccagac ccagtgcccc ggcagcgcga acgccatcag cccttgaccg caccctggag
    16681 gagcgcggcg atgaactgcc gctggaagat cacgtacacg atcaccgtgg gcagcatcac
    16741 gatcagcgac gccgcgaaca gcagcggcag cgcgtcgatg tactggccct ggaacgcgcc
    16801 gagcgccccg gccatggtgc gctcgctcgg gtcgtcgatc atgaccagcg gcaggaggaa
    16861 ctggttccag gtccagagga acaggaggat cccgagcgcc gagagggccg gccgggcgag
    16921 cgggagctgg atgctccgga actcctgcca gatgctcgcc ccgtccacgc gcgcggcctc
    16981 cgacagctcg cgcggcacgc ccacgaagtg cgcgcgcatc cagaacacgc tgaacggcat
    17041 gtacaggccg atgagcggga ggatgaccgc ccacctggtg ttgatcagcc cgaagccggt
    17101 catctggtag tagagcggga tgatgatcgc ctcgaacggg atggtcagcc cgatgatcat
    17161 ggcgacgagg acgtacttcc cgccgggcac ccgcaggttc ccgagcgagt agcccgcgag
    17221 cgtggcgcag acgaggctga cgggtacgac catcaccacg atgaacaggc tcgagagcat
    17281 cagcgtgccg atgttcccga ccgtgaacgc cgtcacgaag ttctcccagt aggcgggcgt
    17341 cggccaggag aagccgttgg gcagcgagtc gggcgactgc agcgcggcgg tgagcatgct
    17401 ggcgaaaggc agcagggtga gcacgaggac cgcgatcagg aggatgcggc ccacgacgag
    17461 ctcggtgcgg ttgacgatca tcagtcgcgc tccctcgaga gtcgttggac ggggagcacg
    17521 agcagcagca cgaacacgag cagcaccacg ccgaacgcgg acgcgaggcc cacctggctc
    17581 tgcacgaagg cgagccggaa gatctcgatg ccgggcacga gcgtcgtggt gcccggcccg
    17641 cccttggtgg tcgtgtagat gatgtcgaac gtgctcaggg cggcgatgac cgtgatggtc
    17701 acgagcaccg cgatctcctg ccggaggccc ggcagggtga tggtgacgaa ctcgcggaag
    17761 aagcctgcgc cgtcgagccg cacggcctcg tagagcgagc cgtcgatctt gcccatgccc
    17821 gtgagcagca gcacggtgca caggcccgtg agcacccagg atccgatgag cccgaccgcg
    17881 gggagcgccg tgccgaagtc ggcgagccag gaacgggaca ggaagcccag ccccaccgca
    17941 tcgaggatgg agttgatggt gccggactgc gcgtacatcc acgaccacgc gatgcccgcc
    18001 gcgacgagcg gcacgatctg cggcaggaac aggatggtgc gcgagatcga ggcgaagggg
    18061 cccggcttca tgccgcgcag cagggtcgcg agcgcgagcc cggccgtgat ggggatcacc
    18121 atgaagaaca ccacgaggat cagcgcgttg aggatgggcg tgagcagccg cgtgtccgtg
    18181 aagatctgca cgtagttgtc gagcccgatg aaggtggacg cgccgatccc gttccacttg
    18241 tagaacgagt actgcaccgc cgtgatgagc ggccagacga cgaacgtgcc gtaggcggcg
    18301 acagcgggca gcagcatgat ccagccgacc gtggccgtgc gacgggcctc gggaccgaga
    18361 cggcgacgcg tcccggaggc gcgggccgcc cccgtgcgcc gcggggcggg ccccgcgagg
    18421 gcggcggccg gtgccgtcgc cctcgcgggg atcgtgcgat ccgtggtgct cactgtgcgg
    18481 cgaggtcctg ctcgtagaag tcctgcgtgg ccttcaggaa gtccgcgggc gccatcttgt
    18541 cggtgagcag cagctgctcg ttgggctgga gcgagccctg gtagatgccg gccgtgctgt
    18601 tggccatgaa gtcgacgaac ccgtcgtcgc ccccgaccac cgcggacagc tcgagggcct
    18661 tggcgatgag gctgccctcc ttcgcggtcg gcagcgcctg cgcgggatcg ccgccgggcg
    18721 aagcgcccgt cacgtcgacc acgatctgac gcgccttctc atcggtcacg atccagttca
    18781 ggaacgcggc gaccacgtcg gcgttcttcg acttggccgg gatggcgaag gtgttgcccg
    18841 tgcccatcgc gacgtgcttc gcgcccgcct cgagcggcgg cacgagggcg aactgcgcgc
    18901 cgcccgtgcc gagggccttc tccacgttcg cggcgtccca gttgccgtcc cacatgaaca
    18961 gcccctggcc ggccgagaag ttcgacacca tggtcgtgta gttgatcgcg ttgacgtccg
    19021 gcggcaggta cccggccttc gcccagtcct ggaactgcgt ggcacccgcc agcgccgcgt
    19081 cggtctggat cgtcgcgccg ggcttgttgt acatccagtc gacgaggccc tgcttgtcgc
    19141 cctgctggtt gatgagcgac tggaggatga aggtccccac gccgtcctgc atgccggtct
    19201 ggatggggag cacgcccgcg tccttcgcct tcgcgaggtc cgcctcgagc tcgtccatgg
    19261 tggacggcat ctcggtgatg cccacctggt cggccagctt ctggttcatg tagatgcccg
    19321 tgacgctgta cccgatgccg aactgccaca gcgagccctc gccgcgcacg ccctggtcgt
    19381 ccatccgggc ccccgcgagc tggcccgccg ggaagcggtc ccagccgtag gcgtcgaagt
    19441 acgggtcgag gttcgtgagg agcccgtcct tgaccgtcgt gccgagcgtc gagaggcgga
    19501 tgaggtccgg ggcgtcgtcg ctcgcgagga gacgcggggt gttcgcgagg aggttctgga
    19561 agctgtcgcg cgtgatgtcg aacttcacgt tcgggtgctg cttcgtgaac tcggcagtga
    19621 gctcgtccgt gaccgggaac ccggtctcgt cctggatccg gatggtgacg tcgtccgtgg
    19681 ggatcgcggt gctcacggcg cccgaggggg cggaggcgac gggtgcgctg ccgggtgcgc
    19741 agctcgcgag ggcgagcgcc gagatggcgg cggcggcggt gagcgctgcc gcccgtcccg
    19801 cccttctcat ggtggacatg cggtgtgact ccttcgtcag gtgggacggg cgggcggtac
    19861 ggtgcggttc gtgtcgtgcg gttgacgcga gcagcgatgc ccgcggatcc agagggtact
    19921 ggtaaatcca tttatcgggt gcagaagatt acgcgtgccg cgctggagcg cgtcaacccg
    19981 cggtcacggc gaccgcctca tcaccggata cgctcacgag gaggaggacg tcacatgcgc
    20041 cagaagcgac cgaccctggc ggacgtggcc cgtctggccg gcctctcccc gaccgcggcg
    20101 tcgcagatcc tcaacggcac gcccgcgacg cgcttctccg aggacgccca ccgtcgcgtc
    20161 ctcgccgcgt cggccgagct cggctaccgc cccaacatgg gtgcgcgggc gctccgcacc
    20221 gaccggtcgc tcaccatcgg cttcatctcg gacgtcgtcg ccacgacgcg cttcgccagc
    20281 ggcctcatcc gcggcgccct cgtcgaggcg gagcgcgcgg gtcatgtggt gctcgtcctc
    20341 gagaccggcg acgaggaggc gcgcgcggcc gaggcggtgt ccgcggtgct cgaccggcag
    20401 gtcgacggca tcgtcttcgc caccatgcgc gcacgcgagc tggtcgtccc cgacgtcccg
    20461 gcctccacgc ccgtcgtgat gctcaacgcc accagcccgc accacgcccg ctcggtcctg
    20521 ccggacgagg aggagggcgg ccgccgcgcg gtcgacctcc tcgccgccgc cggccacgtg
    20581 gacggcatcg cgctgctcgg cagcgacccg gagaccgagc gccgcctctt ccggtcggag
    20641 accgtggccc gccgcctgca cgggatccgc ggcgagatgg ccgagctggg cctcggcttc
    20701 acggccgagc gcgcgtgcgc cgactgggag cccgagaccg gctacgaggc cgcgggcgcg
    20761 atgctggacg cggcgcccgg gatccgcgcg atgatctgcc tgaacgaccg gctggcgttc
    20821 ggcgcctacc aggcgtgcca ggagcgcggg gtccgcgtcg gcgccgagat gtcgctcgtc
    20881 ggcttcgaca acgacgagct ggcgtcctac ctgcggcccg gcctcacgac catcgccctc
    20941 ccgcacgagg agatgggatg cgaggcggtc cggctcgtcc tccgggacgc ggaaccgggc
    21001 gagcgcctcg tggggatgcc ggtggtcgag cgcggctcga tcgcgacggc gtccccggcc
    21061 gacggcggcc cggccgtcgt cgcgcgggag cgcctcgcga ccccggccga gacggcctga
    21121 ggcggggccg ggcggcgtcg tcctaccccg ccgcggcggc ggccagcgga cgctccatca
    21181 cgtggtcggt ctccacggcg tccgggagcc ggaacgagcg ggtcccgacg atgcggaacc
    21241 cgctgcgctc gtagaagcgg atggcccgcg cgttgtgctc gttgacgccg agccagatcc
    21301 cggcgtcggc gtcccggccc cgctccccgg ccagctcgcg cgcgacccgc agcgtctccg
    21361 tcatgagcgg gcgggcgacg ccggcgccgt gcgagccctg ctcgacgtac accttgctca
    21421 cctcgacctc cgggcgcagc cggagcgcgc ccgtcacgtc ggcgtccgtc ggcggcgccg
    21481 cgacgaccat cgtgtagccg accggccggc cgtcgacctc cgcgagcacg acccggcacg
    21541 cgggatccgc gaggtgcgcc cggaagcgcg cggacgagag gaccgtgcgg atgtgctccg
    21601 cgatcgcccg ggccgtcgtg gtcggcgggc aggccagcgc gaaggtgcgg gcggccaggg
    21661 cggccacccc gtcggcgtcg gcagccgtcg cgacgcggaa gacggggacg gcgggggtga
    21721 cggcgggatc cgggatgctc accccacgag cctaggcagg cccgcgcccc gggatgacgc
    21781 caggacccgc ccgacctcgc cggtgccccc gccgggaacg acggaagggc ccgccgaggc
    21841 gggcccttcc tgtgctgcat gtcgtgcgtg cgcttccgcg cggcggtgct agatggagtt
    21901 gacgtccacc gggatgccgg ggccgaaggt cgtggagacc gtggccttct gcacgtagcg
    21961 gcccttcgag gaggacggct tgaggcggac gatctcctcg agcgcggccc cgacgttctc
    22021 ggagagctgc tcgggcgaga agctcgcctt gccgaccacg aagtggacgt tcgcgtgctt
    22081 gtcgacgcgg aactcgatct tgccgccctt gatgtcggac accgcgcgcg cgacgtccgg
    22141 ggtgaccgtt ccggtcttgg ggttgggcat gaggccacgc ggtccgagga ccttgccgag
    22201 acgaccgacc ttgcccatga gctcgggcgt cgagacggcg gagtcgaacg acgtgtagcc
    22261 gcccgccacc ttctcgatga gctcgtcgcc gccgacctcg tcggcgccgg cggcgagggc
    22321 cgcctcggcc gcagggcccg tcgcgaagac gatgacgcgg gcggtcttgc cggtaccgtg
    22381 aggaaggatg acggtgccgc gg
//
