LOCUS       NZ_JADKRR010000001     23159 bp    DNA     linear   CON 16-AUG-2024
DEFINITION  Clavibacter sp. VKM Ac-2872 n1, whole genome shotgun sequence.
ACCESSION   NZ_JADKRR010000001
VERSION     NZ_JADKRR010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Clavibacter sp. VKM Ac-2872
  ORGANISM  Clavibacter sp. VKM Ac-2872
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1  (bases 1 to 2167218)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Draft genome sequences of plant-associated actinobacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2167218)
  AUTHORS   Tarlachkov,S.V., Starodumova,I.P., Dorofeeva,L.V.,
            Prisyazhnaya,N.V., Roubtsova,T.V., Chizhov,V.N., Nadler,S.A.,
            Subbotin,S.A. and Evtushenko,L.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2020) All-Russian Collection of Microorganisms,
            G.K. Skryabin Institute of Biochemistry and Physiology of
            Microorganisms, PSCBR RAS, pr. Nauki, 5, Pushchino, Moscow Region
            142290, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 675x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_015351105.1-RS_2024_08_16
            Annotation Date                   :: 08/16/2024 04:34:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,385
            CDSs (total)                      :: 3,333
            Genes (coding)                    :: 3,309
            CDSs (with protein)               :: 3,309
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 2 of 24
            Pseudo Genes (incomplete)         :: 19 of 24
            Pseudo Genes (internal stop)      :: 4 of 24
            Pseudo Genes (multiple problems)  :: 1 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:57:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2130612
            Orig. end                         :: 2153771
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JADKRR010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23159
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="6"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23159
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23159
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13159](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13159
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(70..83)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            complement(656..2152)
                     /locus_tag="ITJ40_RS10045"
                     /old_locus_tag="ITJ40_10045"
     CDS             complement(656..2152)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038638.1"
                     /locus_tag="ITJ40_RS10045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10045"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_194666861.1"
                     /sec_met_domain="Aldedh (E-value: 2.1e-166, bitscore:
                     551.0, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQHPTEAPASLFIDGTWQPAADGATREIRCPADGSLVGLVSEA
                     GTADVERAIASARAAFDGGAWARTPAPERGDLLLRVADGLVERKAEFARAETLDTGKRL
                     VESEIDMDDIAACFRYFGKLAGQDAGRVVDAGDPDVVSRIVHEPVGVCGLIAPWNYPLL
                     QAAWKIAPALAAGNAFVLKPSELTPHTSILMMRLLADVGLPAGVANLVLGAGAVAGAPL
                     SSHPDVDMVSFTGGLATGRTIAAAAAATVKKVALELGGKNPNVVFADADFDAAVDNALN
                     AAFVHSGQVCSAGARLVVEESVAERFVDELVRRAEGIRLGGPFDPDAETGPLISAAHRD
                     KVHAYVEKGIAEGARLRTGGAFGTGDLEAGYYYLPTVLDRVERGMSVVVDEAFGPVVTV
                     ETFRTEEEAVAIANDTDYGLAGAVWSQDAGKAQRVAQALRHGTIWINDFHPYLPQAEWG
                     GFGQSGVGRELGPTGLAEYQEAKHIYQNTRPQVTGWFPAR"
     gene            complement(2149..4260)
                     /gene="betT"
                     /locus_tag="ITJ40_RS10050"
                     /old_locus_tag="ITJ40_10050"
     CDS             complement(2149..4260)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0071705 - nitrogen compound transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="betT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038639.1"
                     /locus_tag="ITJ40_RS10050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10050"
                     /product="choline BCCT transporter BetT"
                     /protein_id="WP_228511907.1"
                     /transl_table=11
                     /translation="MSTRTPLPASAPDTVGPVVDGAPPGRPRLNKPVFFGSALGIIAIV
                     AWASLAPTAAADAIGAAVAWVSESFGWYYIAVVTLVVGFVVVVAASRAGRTRLGPDDSR
                     PAFNYFTWSAMLFAAGIGIDLMFFSVSEPVTQYLAPPTGDGSTVEAARQAMVLTLFHYG
                     LTGWALYALMGMAFGYFAYRHNLPLSIRAALHPIFGARIHGWIGHLVDIAAVLGTIFGI
                     ATTLGIGVAQLNYGIDFMFGIPEDLAVQAGLIALSVIMAAVSVLTGVEKGIRRLSELNV
                     LCSIALMLFVLFAGRTSFLMDAIVQNVGDVLSRFPAMTLETFAYDRPDAWLSSWTLFFW
                     AWWIAWAPFVGLFLARISRGRTIREFVIGTMVVPFAFILLWISIFGNSALDLVMGGDSA
                     FGAVAMDTPERAFYSLLAEYPGVPLTAAVATFTGLLFYVTSADSDALVMANLTSHLPDA
                     DTDGPKWLRLFWAVATGALTLVMLAVGGVPTLQSATVVMGLPFSVVLLLIMLGLYKALK
                     VEGSLAQSYRSSLPGILSGRSGDAGRGRSWRQRLARAMTYPDRDRAQRFARDVALPALT
                     EVHDELIVQGAGVRLVEGQHREHGICELELEVSMGEGRDFRYAIRPVRYETPTYAPHAA
                     AGAERFYYRMEVFSLEGSRGYDVLDYTREQVIADVLDHYETHLEFLHLNRDDPGSTVVV
                     VPDQPERTA"
     gene            4450..4944
                     /locus_tag="ITJ40_RS10055"
                     /old_locus_tag="ITJ40_10055"
     CDS             4450..4944
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038648.1"
                     /locus_tag="ITJ40_RS10055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10055"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_194666862.1"
                     /transl_table=11
                     /translation="MTAPVTVRPAVPDDADGIAEVHIRTWQETYAHLLPAAYLAGLDVA
                     ARAEDWRRTLTEGSAGTPVFVALDGDRIVGFALAGPARDEDPPRPFQLYAINMVASAHG
                     SGAGQALFDAAVGDSPAYLWAADDNPRAAAFYRRNGFARDGGVERQVYQGAEMVTVRMV
                     R"
     gene            complement(4966..5712)
                     /locus_tag="ITJ40_RS10060"
                     /old_locus_tag="ITJ40_10060"
     CDS             complement(4966..5712)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015780271.1"
                     /locus_tag="ITJ40_RS10060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10060"
                     /product="ABC transporter permease"
                     /protein_id="WP_194666863.1"
                     /transl_table=11
                     /translation="MFRAEAVKLKRSSIWIIAVLLPLLAVVTGTINLANNTQTLDSGWA
                     SFTSQVVLFYGLLFYSMGISLLAAAIWRVEHRGTNWNALLTTTARPIRLVLAKIVAILV
                     PVALMQAVLVGGTAVSGLFVLRLDGPFPVAFLLVGLVATVAALPLIAVQSLLSLLLRSF
                     AAPVALCLVGCVAGVAAVTSTALRPLAEVLPQAINTRALNLGSTAIAGSGGLTAADTLP
                     LLGTSLVLGALAVLLTLAAIRVVKLR"
     gene            complement(5718..6470)
                     /locus_tag="ITJ40_RS10065"
                     /old_locus_tag="ITJ40_10065"
     CDS             complement(5718..6470)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038650.1"
                     /locus_tag="ITJ40_RS10065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10065"
                     /product="ABC transporter permease"
                     /protein_id="WP_194666864.1"
                     /transl_table=11
                     /translation="MRRAVAIEFRKMHRLRSLPLLIGMVVAVAALSSASQFAGSTRAGF
                     DDPGARPWAALLLGYTLMAAMTSPILTAVIASRQTDIEHQAGGWILAAGAGRTAGELCR
                     AKLVALAVLLVPAVLIQSLLVVAAGYAAGIRVPVEVGPWALYTLLLYLVDVAFCALHVW
                     LAARVENQLISVGVGMLGAFLAVFSLLLPSIASRAIPWGYYAVISQAGQSDAGVDYVAS
                     PLGWIAGFLVVVAAAFALATVRLDRVER"
     gene            complement(6467..7366)
                     /locus_tag="ITJ40_RS10070"
                     /old_locus_tag="ITJ40_10070"
     CDS             complement(6467..7366)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038651.1"
                     /locus_tag="ITJ40_RS10070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10070"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_194666865.1"
                     /transl_table=11
                     /translation="MSAVIATRGLTKRFRDHVAVDALDIAVPQGSVYGFLGPNGSGKST
                     TMKMLLGLTQPTSGEIHLFGQRLTPATRGGLLPSIGSMIEAPAGYGHLTGWENMRIVRD
                     MLGLAEAQVERAFATVRLTQHRDKLVRRYSLGMKQRLGIAMALARDPSLLVLDEPTNGL
                     DPAGIEEVRSLLMDLAGQGITVMVSSHLLDEIEKMAGVLGILSEGRMIFQGTRAELFEH
                     SIPDLVIETSAPDLAMAVVAGAARIPEGIRLTARSQDETADIVRRLVAADVPVHEVRRL
                     PQSLEDVFMDITGRGGQL"
     gene            complement(7535..8209)
                     /locus_tag="ITJ40_RS10075"
                     /old_locus_tag="ITJ40_10075"
     CDS             complement(7535..8209)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038652.1"
                     /locus_tag="ITJ40_RS10075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10075"
                     /product="response regulator transcription factor"
                     /protein_id="WP_194666866.1"
                     /transl_table=11
                     /translation="MSDAPALIRVVVVDDQSLVRDGFARIVDAQPDMAAVGVCADGEQA
                     VARVAELRPDVVLMDVRMPVLDGIEATRRLVAGGHAAGTRILGLTTHDTDAYALRMLRA
                     GAVGFLLKDSTAVQLVDAIRSVHNGTFAASMSTTQRLLDRLAAEEAAQTDPDTAALDVL
                     TDRERVVFTRLVTGASNPEIARDLSIAEVTVKTHVGHILTKLAVRDRVHLVIWAHRRGL
                     AA"
     gene            complement(8206..9342)
                     /locus_tag="ITJ40_RS17445"
                     /old_locus_tag="ITJ40_10080"
     CDS             complement(8206..9342)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="ITJ40_RS17445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10080"
                     /product="histidine kinase"
                     /protein_id="WP_228512320.1"
                     /transl_table=11
                     /translation="MRRGSPRAHVDRVVAGAAVVLCAVMGVLGQPDWIWSSLMALTLAV
                     RHARPVVAALLATAISSAHMLVTSSLLFPGDVVLLVAAYSVSAHAADRFRHAGLALGAC
                     FVVVLAARTLTGGELGSTGSVGMVIALVSVSFAIAWAAGLLERRRTEAVRTAELRTMLS
                     ERDADARTRIAAYEERERISDDMHDVLAHTLTSVIVQAESGRATAPSPEVSRMFRTISE
                     TSRAALHEVRGLLAPTEADADVRPVPGWDDVDALVEGFRGSGLRIERQDAGTPRPLLPG
                     VGSAVYRVVQESLTNALRHGAGAPARLRVEWSPDALAVSVANAVGRDLRGRPVQEHRGL
                     AAIRRRCALHGGQARYACGDEFVVQARWPTAPLGGSSP"
     CDS             complement(9514..9690)
                     /gene="allorf_2140126_2140302"
                     /locus_tag="allorf_2140126_2140302"
                     /protein_id="allorf_2140126_2140302"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFLLSRMDPSRSARTVVVRAAPIPMARGPSQVRLAPGDRGSARLG
                     RCGVDAQPVRDPS"
     CDS_motif       complement(9628..9690)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFLLSRMDPSRSARTVVVRAA"
                     /locus_tag="allorf_2140126_2140302_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9514..9627)
                     /prepeptide="core"
                     /locus_tag="allorf_2140126_2140302_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="3787.3"
                     /monoisotopic_mass="3785.0"
                     /core_sequence="PIPMARGPSQVRLAPGDRGSARLGRCGVDAQPVRDPS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFLLSRMDPSRSARTVVVRAA"
                     /leader_location="[9627:9690](-)"
                     /alternative_weights="3805.3"
                     /alternative_weights="3823.3"
     gene            9703..9909
                     /locus_tag="ITJ40_RS10085"
                     /old_locus_tag="ITJ40_10085"
     CDS             9703..9909
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038654.1"
                     /locus_tag="ITJ40_RS10085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10085"
                     /product="hypothetical protein"
                     /protein_id="WP_194666868.1"
                     /transl_table=11
                     /translation="MNDILETEPPVMVSPRWDMLLDAGDETSPSVQTQIDAEFRRVVSP
                     YMASSGWLCTLTIECGTFICACR"
     CDS_motif       9703..9843
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNDILETEPPVMVSPRWDMLLDAGDETSPSVQTQIDAEFRRVVSPYM"
                     /locus_tag="ITJ40_RS10085_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9844..9909
                     /prepeptide="core"
                     /locus_tag="ITJ40_RS10085_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.60"
                     /molecular_weight="2145.5"
                     /monoisotopic_mass="2144.0"
                     /core_sequence="ASSGWLCTLTIECGTFICACR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNDILETEPPVMVSPRWDMLLDAGDETSPSVQTQIDAEFRR
                     VVSPYM"
                     /leader_location="[9702:9843](+)"
                     /alternative_weights="2163.5"
     gene            10001..13159
                     /locus_tag="ITJ40_RS10090"
                     /old_locus_tag="ITJ40_10090"
     CDS             10001..13159
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="ITJ40_RS10090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10090"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_194666869.1"
                     /sec_met_domain="DUF4135 (E-value: 2.6e-87, bitscore:
                     290.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.3e-46, bitscore:
                     155.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITAVELSLLQAARLRERRAATRADARPVPELTRAWRVDALVDD
                     GTHAAYLAGQLLDGDDLVALLAGDAWTPRAASADWLARVDPWLVQPPVSAEAYAPANGH
                     LVVEDTRVAGLPFAALLGPVVGAQRAHLDGRPWLSPTARADLLDGLAERLATLALRVLI
                     AELAADPGPDRYARLEARLADPAHRAAFLSRHPVLARDLVTAIGSWRAHVARVLDRLHV
                     DHGDLVRVGLAPERLDALEAVDLGSGDPHDGGQSVATLRFSDGRRLVYKPRDCRVFALY
                     RDLVDALAPALPAEIRLRAAAVLPRDGYGWVEFVAHADDASAAIPLSRHLGRLGSLLAV
                     AHVLGASDLHLENVIASADGPVPIDLETLIQNRSEVDGEDGTALRRASRMLNASVLGSG
                     ILPVQLTTGEGTSIDVSVSTGGLHDAGTTATVHQVVDAATDGMRIEAREMPVGRSRNQP
                     PGATLARIRSGRAALADGYARTFRAVIELRAEVRAILSAAPDMSSRHIVRATRSYSLLL
                     TEMRRPRPLRSGIDRDHLLRHLWTRIEDHPADAALIEAEERALWRLDVPLFSTRMDARA
                     LIADDREVAPGRFARTTREDVLDRLAGLTLDDLPESLRLIDESVLAATATPDGDDDRDA
                     ATGRQAADAAASPARAPRMDDDALREAARGQARLLLDSAVLGRDDATWIGLSSSLDSSG
                     LEYRPAGPTLYDGLAGIAFAATHAHGVLPDLGLDDLAGRAMHAVTAILDDWTRGLIDLP
                     VGAYSGAAGLLFALAHHDARVGDDAHRDLRAAAVRRLGEVAHEDTHLDVMAGVAGACAV
                     VAGLPEGATEGGRATLRALVGRLMSTAVEVDGGALVWETGAERARLGGFSHGASGVGWA
                     LARTAGVLDDEAIADAAVRALRFDDALFDPSRRRWRDARPEARSATGSFPAHWCHGTAG
                     IAMARADAAAALRRTDLLELALVGARETASDALPSDDSLCHGTLGNLIAVRGVTRRIGG
                     EAGLAEYRDRALRRVLRAGPRSGLPEGVTSVRGLMLGTAGALYALCRELDPGIPDALLL
                     EGPR"
     gene            complement(13224..14507)
                     /locus_tag="ITJ40_RS10095"
                     /old_locus_tag="ITJ40_10095"
     CDS             complement(13224..14507)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012298658.1"
                     /locus_tag="ITJ40_RS10095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10095"
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_194666870.1"
                     /transl_table=11
                     /translation="MSDVPSAAPAGWFPDGSGQLRYWDGAVWTQHVAPMVQPAAPQAQA
                     PSAAALAAVAATQQAEQAKAARAADAARIQAERAAVAEQQRAAKVAQREAAMQAKAAER
                     EAAARAKAERAAATAAIPVAAAAWPAPTAQVAPKAVAPVIADTRPSRHPATTWVVTSVV
                     ALAVLIITAMGGFGGMFVSLGLVALATGLYPLLTGRRSWIPALATRPRSSATAAGAILL
                     LVMGAVVPVAASTSGPRQVDAISASASPTPTSTPTPSATPTPVVHVVEDVSAKSATDAR
                     ALLREAGYVVQYVLESGGVPSVTDGMTVVSQSPVAGSRVDAGSTVTLTLLTLLAPAPTP
                     TPEPTVAPTVAPAPQPAAPAPAPVAPAPAPAPAAPAPAPAQQTGLIKPGAFCSNADVGT
                     VAQAANGRSYKCGGHGPDANGKNHWNTM"
     misc_feature    complement(14582..14596)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     misc_feature    14583..14597
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 23.69"
                     /tool="antismash"
     gene            14955..16133
                     /locus_tag="ITJ40_RS10100"
                     /old_locus_tag="ITJ40_10100"
     CDS             14955..16133
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ITJ40_RS10100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ITJ40_10100"
                     /product="hypothetical protein"
                     /protein_id="WP_194666871.1"
                     /transl_table=11
                     /translation="MSIDVLLGRSTVPIDEAVFRALLDNSVAGTYADYSYALERGNIRF
                     TTLVKLARKGEIPYSLFFAPLPVVEAQVGAKTEKLLAGTSKKTFSLGSRSRVELRDIEL
                     IIKDLLRKQELLKRHDQSLVENRVVGILHKPGATPDADANKLMAAIDLRPQDLRKCRTK
                     EKALDLMIERLEAKQILVSRSVQHYMPQRLTHVEFSGMTIRDKIVPFIFLAGGEHNDYQ
                     EPVGRTIFTLALMTVLIGRRIFAPMTWDGASVGTEVGREYDIAGAMLMPRDQMKELAPT
                     SLEDMKAISSEFKVTASAVTVRAMRLSLITGETATAYLDDLRLDYNQNKQSKPMNQPLP
                     ENAIRKYNGNELTKRMLDALSSNSISTSDFCRSVCLNRIKPTQIDDLRRALS"
     misc_feature    15249..15251
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15297..15299
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15348..15350
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15390..15392
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16080..16082
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16136..16654
                     /locus_tag="ITJ40_RS10105"
                     /old_locus_tag="ITJ40_10105"
     CDS             16136..16654
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025022.4"
                     /locus_tag="ITJ40_RS10105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10105"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_228512322.1"
                     /transl_table=11
                     /translation="MFGTRYVIDTNALIQMGRERRESNFFSLNAVIPSEVLHEAEGFPD
                     YAQLLTFDFATTPRVLEYLTDVMNTIHAEDTSLVDLYKNLGGADPLVVACALTGKEIDS
                     QYLDAPKWVIVTGDEAVSAKAREFNLDVVDVTTFAALIDEAQATATATATATATATATA
                     TATATFDRD"
     CDS             16663..16785
                     /gene="allorf_2147275_2147397"
                     /locus_tag="allorf_2147275_2147397"
                     /protein_id="allorf_2147275_2147397"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMTKSPHALRRLHGSRPRSRCISCEEMCKITLWTLVDGTQ"
     CDS_motif       16663..16707
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMTKSPHALRRLHGS"
                     /locus_tag="allorf_2147275_2147397_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       16708..16785
                     /prepeptide="core"
                     /locus_tag="allorf_2147275_2147397_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="2836.3"
                     /monoisotopic_mass="2834.4"
                     /core_sequence="RPRSRCISCEEMCKITLWTLVDGTQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMTKSPHALRRLHGS"
                     /leader_location="[16662:16707](+)"
                     /alternative_weights="2854.3"
                     /alternative_weights="2872.4"
     CDS             complement(16873..17055)
                     /gene="allorf_2147485_2147667"
                     /locus_tag="allorf_2147485_2147667"
                     /protein_id="allorf_2147485_2147667"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGQRAVAQLGSALDWGSRGRRFKSCQPDGHASEGPDGSGRGIRRM
                     YAGIVAVNSMVDAPT"
     CDS_motif       complement(17023..17055)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGQRAVAQLGS"
                     /locus_tag="allorf_2147485_2147667_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16873..17022)
                     /prepeptide="core"
                     /locus_tag="allorf_2147485_2147667_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="5082.6"
                     /monoisotopic_mass="5079.5"
                     /core_sequence="ALDWGSRGRRFKSCQPDGHASEGPDGSGRGIRRMYAGIVAVNS
                     MVDAPT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGQRAVAQLGS"
                     /leader_location="[17022:17055](-)"
                     /alternative_weights="5100.6"
                     /alternative_weights="5118.7"
                     /alternative_weights="5136.7"
                     /alternative_weights="5154.7"
                     /alternative_weights="5172.7"
     CDS             complement(16899..17030)
                     /gene="allorf_2147511_2147642"
                     /locus_tag="allorf_2147511_2147642"
                     /protein_id="allorf_2147511_2147642"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVAHLTGGQGVAGSNPVSPTDMPRKDLMGPAGAFVVCTQASLR"
     CDS_motif       complement(16989..17030)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVAHLTGGQGVAGS"
                     /locus_tag="allorf_2147511_2147642_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16899..16988)
                     /prepeptide="core"
                     /locus_tag="allorf_2147511_2147642_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="2987.5"
                     /monoisotopic_mass="2985.5"
                     /core_sequence="NPVSPTDMPRKDLMGPAGAFVVCTQASLR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVAHLTGGQGVAGS"
                     /leader_location="[16988:17030](-)"
                     /alternative_weights="3005.5"
                     /alternative_weights="3023.5"
                     /alternative_weights="3041.5"
     tRNA            complement(16973..17046)
                     /anticodon=(pos:complement(2147622..2147624),aa:Pro,
                     seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="ITJ40_RS10110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="ITJ40_10110"
                     /product="tRNA-Pro"
     gene            complement(16973..17046)
                     /locus_tag="ITJ40_RS10110"
                     /old_locus_tag="ITJ40_10110"
     gene            complement(17120..17659)
                     /locus_tag="ITJ40_RS10115"
                     /old_locus_tag="ITJ40_10115"
     CDS             complement(17120..17659)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038659.1"
                     /locus_tag="ITJ40_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10115"
                     /product="hypothetical protein"
                     /protein_id="WP_194666873.1"
                     /transl_table=11
                     /translation="MDQLLSRLDRIAAGRQAGHVIAEDMRDHPWTTRAFRWIRWILIAE
                     TAVGATAVAIALTLASDGIAIAPAVWFRSFVVLAMTITLYYFAWRASAGYWWAYSRLRL
                     FSQIFPIVTLVVAAIPGLYPLWMVIEQIVFSLLLIGVADILRSDHMRDAFPKPGRVAAP
                     GAPDPSAPGRPGGAPA"
     misc_feature    complement(17643..17658)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.44"
                     /tool="antismash"
     gene            17948..19273
                     /locus_tag="ITJ40_RS10120"
                     /old_locus_tag="ITJ40_10120"
     CDS             17948..19273
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038660.1"
                     /locus_tag="ITJ40_RS10120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10120"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_228511911.1"
                     /transl_table=11
                     /translation="MTLIDREPRPASGSPTPARGTAPAKTDRPRPAPLGDAPVDRWKGA
                     PRPTTPAAWIARAREVADILAVDQVERDRAGASPHQEVALLKHAGLVTLLGPAEHGGGG
                     QTWDTAYKVIRAVARGDGSIGQLLGYHYLWAWAARLVGTDAQIEAVEKLATTGNLLFGG
                     AVNPRDSDLVIREDGDDLIFSGRKSFSTGGVVSDLTVLEGVIEGTDTHVFAIVPTDQPG
                     IVFGHDWDSLGQRLTESGSVEIRDVRVPWTDAAGFVDKVFQPLVYGTLNVPAIQLVFAN
                     FYQGIAEGALETAAAYTRSTTRAWPYGGDDKERATDEWYVLEGYGQLQSKLWASEALLD
                     RVGAEISAVLHAPREKLTERKRGEIAVRVAAAKARIAEDGLEVGTRILELTGARASSSK
                     AGLDIFWRNLRTHTLHDPIPYKRREVGRHVLLGEIPEPTWYT"
     gene            complement(19366..20874)
                     /gene="der"
                     /locus_tag="ITJ40_RS10125"
                     /old_locus_tag="ITJ40_10125"
     CDS             complement(19366..20874)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038661.1"
                     /locus_tag="ITJ40_RS10125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10125"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_194666874.1"
                     /transl_table=11
                     /translation="MADHDDDFPELDSGLHERLSSIDEELAAQRAQTLRAGLEDYELDD
                     EDLEVLESATDDPDQVTYLPALPVLAVVGRPNVGKSALINRILGRREAVVEDTPGVTRD
                     RVSYKAEYAGRWFTLVDTGGWEPDAKGINASVAMQAEIAMDLADAVLFVVDANVGATST
                     DEHVVRLLRKTKKTVILAANKVDDARQEPNAASLWSLGLGEPHPVSALHGRGVADLLDL
                     VLKTLPLVSKVAKEEVGGPRRVAILGRPNVGKSSLLNKAAGEERVVVNELAGTTRDPVD
                     EQVEIAGKVWRFVDTAGIRRRMHLAQGADFYASLRTSAALEKAEVAVVMIDVSEVISEQ
                     DIRIIELVLESGRALVLAFNKWDLLDDERRRYLEREIETDLAHVSWAPRVNISARTGRH
                     MEKLVPALETALESWDTRIATGKFNAFLAELTAAHPHPVRGGKQPRILFGTQASSRPPT
                     FVLFTTGYLDPQYRRYIQRRLREIYGFEGSPIIVNMRVREKRKR"
     misc_feature    20866..20880
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(20915..21658)
                     /gene="cmk"
                     /locus_tag="ITJ40_RS10130"
                     /old_locus_tag="ITJ40_10130"
     CDS             complement(20915..21658)
                     /EC_number="2.7.4.25"
                     /GO_function="GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /gene="cmk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490614.1"
                     /locus_tag="ITJ40_RS10130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10130"
                     /product="(d)CMP kinase"
                     /protein_id="WP_228511913.1"
                     /transl_table=11
                     /translation="MTGDAVNAPDPTAPDPLEDVLLVDATLNRTVVAVDGPAGSGKSSV
                     SRAAARALGFDYQDTGAAYRALSWFALESGVDTEDPATVTSLIEGFDYDIAIDPDQTRV
                     SVRGTDVTEAIREPRVSAVVSHVARVPEVRHYMVELFRSLMASSDKPGIVVEGRDITTV
                     VAPDAQVRILLTASPEARMSRRSAETSTQSAAAVGESLASRDRADSQVVDFMNAADGVT
                     TIDSTDIDFDQTVQAVVDLVHARTD"
     gene            complement(21655..22773)
                     /locus_tag="ITJ40_RS10135"
                     /old_locus_tag="ITJ40_10135"
     CDS             complement(21655..22773)
                     /EC_number="1.3.1.12"
                     /GO_function="GO:0004665 - prephenate dehydrogenase (NADP+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012298649.1"
                     /locus_tag="ITJ40_RS10135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ITJ40_10135"
                     /product="prephenate dehydrogenase"
                     /protein_id="WP_194666875.1"
                     /transl_table=11
                     /translation="MSEAAGAAAATDTRVQGTVRIVGTGLLGTSIGLGLSARGVDVVLA
                     DASPTTLRLAADMGAGRIADIAVVPDRPSLVVVCVPPDVTARVVAAELAAHPDALVTDV
                     ASVKAAPLAELRAMGADLSRYLGSHPLAGRERGGPVSATGDLFLGRPWVIAGHDGITYA
                     AGAPVEQLILDLGAVPIEMTAEEHDASVALVSHVPQVVASLLASRLADGDAAALGLSGQ
                     GLRDTTRIASSDAALWVQILGANAARVVPILQALRTDLDDVIDALDDVDAQGARLRVAE
                     RIHAGNAGVARIPGKHGQDRRFAAITVMIDDRPGQLAALISDVGAADVSIEDLRLEHSQ
                     GAQVGLVEIAVLPEARDRLVARLEERDWRIAG"
     misc_feature    complement(22882..22896)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(22981..22995)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 ttcggccggt cggcgatcgg gtgcaggtac gagaccgacg aggacgcgcg cgtgccgtcc
       61 gcctgccggt tgatctggaa gaacccggcg ccgttccgca cggtctggcc ggtgttgaag
      121 cgcgtgcgcg ggatcccggc ctgctcgcac gcgtccagca gcgccacgcc ggacgggtcg
      181 cgcggcggca cgttcatgag gtgcaccggg ccgtcgtggc cgtggtgcgg ctccggatcc
      241 tcgttcgtct ccagccgctg gtagatcggg taggtgctgt cggcgtgcca gcccgtggcg
      301 ccgtgctcgt gcgcccagcc gtcgaggtcc tcgcgcggcg cccagaacgc gatgcacgag
      361 ttgtggctcg agcagccgcc gagcaccttg gcgcgcgcgt gccgcatgaa ggagttgccg
      421 ttctcctgct cctcgatggg gtagtcccag tcgtagccgg actcgagcag ctccatccac
      481 ctgtcgaggc ggaggaccac gtcgaggtcc ctgtcgtgcg ggccggcctc gatgagggcc
      541 acctgcatgt cgggatcctc gctgaggcgg gccgcgacgg ccgcgccggc ggatcccccg
      601 ccgacgacca cgtagtcgta ctcggtgccg gtcatgtcgt ctcccctgct gtcgctcatc
      661 gcgccgggaa ccatccggtc acctgcgggc gcgtgttctg gtagatgtgc ttggcctcct
      721 ggtactcggc gaggccggtc ggaccgagct cgcggccgac gccggactgc ccgaagccgc
      781 cccactccgc ctgcggcagg taggggtgga agtcgttgat ccagatggtg ccgtggcgga
      841 gcgcctgcgc gacccgctgc gccttcccgg cgtcctggga ccacaccgcg cccgcgagcc
      901 cgtagtcggt gtcgttcgcg atggcgaccg cctcctcctc cgtgcggaac gtctcgaccg
      961 tgacgacggg tccgaaggcc tcgtcgacca ccacggacat gccgcgctcg acccggtcga
     1021 gcacggtcgg caggtagtag tagccggcct cgaggtcgcc cgtgccgaac gcgccgcccg
     1081 tgcggaggcg cgcgccctcg gcgatcccct tctcgacgta cgcgtgcacc ttgtcgcggt
     1141 gcgcggccga gatgagcggg ccggtctcgg cgtcggggtc gaacgggccg ccgaggcgga
     1201 tcccctcggc ccggcgcacg agctcgtcca cgaagcgctc ggcgacggac tcctccacca
     1261 cgagccgcgc gcccgccgag cagacctggc cggagtgcac gaaggcggcg ttgagggcgt
     1321 tgtcgacggc cgcgtcgaag tcggcgtcgg cgaacaccac gttggggttc ttgccgccca
     1381 gctccagcgc gaccttcttc acggtcgccg ccgcggccgc cgcgatggtg cgtcccgtgg
     1441 cgaggccgcc cgtgaacgag accatgtcca cgtcggggtg gctcgacagc ggcgcgcccg
     1501 cgacggcgcc cgcgccgagc accaggttgg cgacgccggc ggggaggccg acgtcggcga
     1561 ggagccgcat catgaggatc gaggtgtgcg gcgtcagctc gctgggcttg agcacgaacg
     1621 cgttgcccgc ggcgagcgcg ggcgcgatct tccacgcggc ctgcagcagc gggtagttcc
     1681 acggcgcgat gaggccgcac acgccgacgg gctcgtggac gatgcggctc acgacgtcgg
     1741 ggtcgcccgc gtcgacgacg cggccggcgt cctggcccgc gagcttgccg aagtaccgga
     1801 agcaggcggc gatgtcgtcc atgtcgatct cgctctccac caggcgcttg ccggtgtcga
     1861 gggtctcggc gcgggcgaac tccgccttcc gctcgacgag gccgtcggcc acgcggagga
     1921 ggaggtcgcc gcgctcgggc gcgggggtgc gcgcccaggc gccgccgtcg aacgcggcgc
     1981 gggcgctcgc gatcgcgcgc tcgacgtcgg cggtgcccgc ctcggagacg agcccgacga
     2041 gggatccgtc cgccgggcag cggatctcgc gcgtcgcgcc gtccgcggcg ggctgccagg
     2101 tgccgtcgat gaacagggag gcgggcgcct ccgtggggtg ctgggtggtc atgcggtcct
     2161 ctcgggctgg tcggggacga cgacgacggt gctgcccggg tcgtcgcggt tgaggtggag
     2221 gaactcgagg tgggtctcgt agtggtcgag gacgtcggcg atcacctgct cgcgcgtgta
     2281 gtcgaggacg tcgtagccgc ggctgccctc cagcgagaac acctccatgc ggtagtagaa
     2341 gcgctccgcc ccggccgccg cgtgcggcgc gtaggtgggc gtctcgtagc gcaccggccg
     2401 gatggcgtag cggaagtcgc gcccctcgcc catggacacc tcgagctcca gctcgcagat
     2461 gccgtgctcc cggtgctggc cctcgacgag gcgcacgccg gcgccctgca cgatgagctc
     2521 gtcgtgcact tcggtgagcg cgggcagcgc cacgtcccgg gcgaagcgct gcgcgcggtc
     2581 gcgatccggg taggtcatcg cgcgggcgag ccgctggcgc cagctgcgtc cgcgtcccgc
     2641 gtcgccggag cggcccgaca ggatgcccgg caggctcgac cggtagctct gggcgaggga
     2701 tccctccacc ttcagggcct tgtagagccc gagcatgatg agcagcagca ccaccgagaa
     2761 cggcagcccc atcaccacgg tcgcgctctg cagggtcggc acgccgccga ccgcgagcat
     2821 cacgagcgtg agcgcgccgg tggcgacggc ccagaacagg cgcagccact tgggtccgtc
     2881 ggtgtcggcg tcgggcaggt gcgaggtgag gttcgccatg acgagcgcgt cggagtcggc
     2941 ggaggtgacg tagaagagga gccccgtgaa ggtcgcgacg gcggccgtga gcggcacccc
     3001 cgggtactcg gcgaggagcg agtagaacgc gcgctccggg gtgtccatcg cgacggcgcc
     3061 gaacgcgctg tcgccgccca tgacgaggtc gagggcgctg ttcccgaaga tggagatcca
     3121 cagcaggatg aaggcgaacg ggaccaccat cgtgccgatg acgaactcgc ggatggtgcg
     3181 gccgcgggag atgcgggcga ggaacaggcc cacgaacggc gcccacgcga tccaccaggc
     3241 ccagaagaag agggtccagc tgctgagcca cgcgtcgggg cggtcgtagg cgaaggtctc
     3301 gagcgtcatg gcggggaagc ggctgagcac gtcgccgacg ttctgcacga tcgcgtccat
     3361 gaggaagctc gtgcggcccg cgaagagcac gaagagcatg agcgcgatgg agcagagcac
     3421 gttgagctcc gacaggcgcc ggatcccctt ctcgaccccc gtgagcaccg agaccgcggc
     3481 catgatcacg gacagggcga tgaggcccgc ctgcacggcc aggtcctccg ggatcccgaa
     3541 catgaagtcg atcccgtagt tgagctgcgc gacgccgatg ccgagcgtgg tcgcgatgcc
     3601 gaagatcgtg ccgaggacgg cggcgatgtc gacgaggtgg ccgatccacc cgtggatgcg
     3661 cgcgccgaag atcgggtgga gggcggcgcg gatgctcagc ggcaggttgt ggcggtaggc
     3721 gaagtagccg aacgccatgc ccatgagcgc gtagagcgcc cagccggtga ggccgtagtg
     3781 gaagagcgtg agcaccatgg cctgccgcgc ggcctcgacg gtggacccgt cgccggtggg
     3841 cggggcgagg tactgggtga cgggctccga gacggagaag aacatcaggt cgatgccgat
     3901 gcccgcggcg aagagcatcg ccgaccaggt gaagtagttg aacgcgggcc gggagtcgtc
     3961 gggcccgagg cgcgtgcggc cggcgcggga ggccgccacg acgaccacga agcccacgac
     4021 cagcgtgacg acggcgatgt agtaccagcc gaagctctcc gagacccagg cgacggcggc
     4081 gccgatcgcg tcggcggcgg cggtcggggc gagggaggcc caggcgacga tggcgatgat
     4141 gccgagggcg gagccgaaga acacgggctt gttgaggcgg gggcggccgg gcggcgcgcc
     4201 gtcgacgacg gggcccacgg tgtcgggggc ggaagcgggc aggggtgtgc gagtactcat
     4261 cgcgtccttc gctgggaggg gaatgaggct tcggtcggca cccggggtct cacggaccac
     4321 accgggtgcg cgcccaccct agcgaggggc cctcccccgg ccgcaagccg gatcgcgcct
     4381 gcggtagggt ccgcgcgcgg gcgcgtgggg cgggaccggg ccgctccggc cgccccgtat
     4441 cgtggcggga tgaccgcgcc cgtgaccgtc cgccccgccg tgcccgacga cgccgacggg
     4501 atcgccgagg tccacatccg tacctggcag gagacgtacg cgcatctgct cccggccgcg
     4561 tacctcgccg gtctcgacgt cgcggcgcgc gccgaggact ggcgtcgcac gctgacggag
     4621 ggatccgccg ggacgccggt cttcgtcgcc ctcgacggcg accgcatcgt cggcttcgcc
     4681 ctcgcgggac cggcgcgcga cgaggatccg ccgcgcccgt tccagctcta cgcgatcaac
     4741 atggtcgcgt cggcccacgg ctcgggcgcc ggccaggccc tgttcgacgc ggccgtcggc
     4801 gactcccccg cctacctctg ggccgccgac gacaaccccc gcgcggcggc gttctaccgc
     4861 cggaacgggt tcgcgcgcga cggcggcgtg gagcggcagg tgtaccaggg agccgagatg
     4921 gtcacggtgc ggatggtgcg atgagggtcg agggcgacgc ggcgctcagc gcagcttgac
     4981 cacgcggatc gccgcgagcg tgaggaggac ggccagcgcg ccgaggacca ggctggtccc
     5041 gaggagcggc agggtgtccg ccgccgtgag ccccccggat cccgcgatcg ccgtcgaccc
     5101 caagttcagc gcccgggtgt tgatcgcctg cggcagcacc tccgccagcg gacgcagggc
     5161 cgtcgaggtc acggcggcga cgcccgccac gcatccgacc aggcagagcg cgaccggcgc
     5221 cgcgaaggag cgcagcagca gcgacagcag cgactggacg gcgatgaggg gcagcgccgc
     5281 cacggtcgcg accagcccga cgaggaggaa cgcgacgggg aacggaccgt ccagccggag
     5341 cacgaacagc ccggagaccg ccgtgccgcc gacgagcacc gcctgcatca gcgccaccgg
     5401 caccaggatc gccacgatct tcgccagcac gagccggatc ggacgcgcgg tcgtcgtcag
     5461 cagggcgttc cagttggtgc cgcggtgctc gacgcgccag atggccgccg cgagcaggct
     5521 gatgcccatc gagtagaaca gcagcccgta gaacagcacc acctgcgagg tgaacgacgc
     5581 ccacccggag tcgagggtct gcgtgttgtt cgccaggttg atggtgccgg tgacgacggc
     5641 caggagcggc agcagcacgg cgatgatcca gatgctggag cgcttgagct tcacggcctc
     5701 tgctcggaac acgcccgtca cctctccacg cggtcgagtc ggacggtcgc gagggcgaag
     5761 gccgccgcga ccacgacgag gaagccggcg atccacccga gcggggaggc gacgtagtcc
     5821 acgcccgcgt ccgactggcc ggcctgcgag atgacggcgt agtagcccca cgggatggcg
     5881 cggctggcga tggacgggag caggagggag aagacggcga ggaaggcgcc cagcatcccg
     5941 acgcccacgc tgatgagctg gttctccacg cgtgccgcga gccagacgtg cagcgcgcag
     6001 aacgccacgt cgaccaggta gagcaggagc gtgtagagcg cccagggccc tacctcgacg
     6061 ggcacccgga tcccggcggc gtacccggcc gcgaccacga ggagcgactg gatcagcacg
     6121 gcggggacga ggagcaccgc cagggccacg agcttggcgc ggcagagctc gccggccgtg
     6181 cgtcccgcgc ccgccgcgag gatccacccg cccgcctggt gctcgatgtc ggtctggcgg
     6241 ctcgcgatca cggccgtgag gatgggcgag gtcatcgccg ccatgagcgt gtacccgagc
     6301 agcagcgcgg cccaggggcg ggcgccggga tcgtcgaagc ccgcgcgcgt gctgcccgcg
     6361 aactgcgacg ccgagctcag ggcggcgacg gcgacgacca tgccgatgag cagcgggagc
     6421 gagcgcagcc ggtgcatctt ccggaactcg atcgcgacgg cgcgcctcac agctgccccc
     6481 cgcgcccggt gatgtccatg aacacgtcct ccaggctctg cgggagccgc cgcacctcgt
     6541 gcacgggtac gtcggccgcc acgagccggc gcacgatgtc ggcggtctcg tcctgggatc
     6601 gggcggtgag ccggatcccc tccgggatcc tggccgcacc cgcgaccacc gccatggcca
     6661 ggtccggcgc cgacgtctcg atgacgagat cggggatcga gtgctcgaac agctcggcgc
     6721 gcgtgccctg gaagatcatc cggccctcgg acaggatgcc gagcacgccc gccatcttct
     6781 cgatctcgtc gagcaggtgg ctggagacca tcacggtgat gccctggccg gccaggtcca
     6841 tgaggaggga gcggacctcc tcgatgcccg ccggatccag cccgttggtg ggctcgtcga
     6901 ggacgagcag ggaggggtcg cgggcgaggg ccatggcgat cccgaggcgc tgcttcatgc
     6961 cgagcgagta ccggcgcacc agcttgtcgc ggtgctgcgt gagccgcacg gtggcgaacg
     7021 cccgctccac ctgcgcctcc gcgagcccga gcatgtcgcg cacgatccgc atgttctccc
     7081 accccgtgag gtggccgtag cccgcgggtg cctcgatcat ggagccgatg gacggcagga
     7141 gcccgccgcg ggtcgccggc gtcagccgct ggccgaacag gtggatctcc cccgacgtgg
     7201 gctgcgtgag cccgagcagc atcttcatgg tcgtggactt gccggagccg ttgggcccga
     7261 ggaacccgta cacggacccc tgcggcaccg cgatgtcgag cgcatcgacg gcgacgtgat
     7321 cccggaaccg cttggtgagc ccgcgggtgg cgatgacggc gctcatcggc gcgggggtgt
     7381 cgtggtcggc atgcccccat cctcggccgg ccggtgcgcg ggcgcatcgt gccgtgggcc
     7441 ggtcccgccc ggtcgcctct cctgcgatgg gaggagaggt cggcgggacc gcgggaccgg
     7501 tgcctcgcgg gctcgcgggc tcgcgccgga gcggtcaggc ggcgaggccc cgccggtgcg
     7561 cccagatcac caggtggacg cggtcgcgca cggcgagctt ggtgaggatg tgcccgacgt
     7621 gcgtcttcac cgtgacctcc gcgatggaca ggtcgcgggc gatctccggg ttggacgcgc
     7681 ccgtgacgag ccgcgtgaac acgacccgct cccggtcggt caggacgtcg agcgcggcgg
     7741 tgtccgggtc ggtctgcgcc gcctcctccg ccgccagccg gtcgaggagg cgctgcgtgg
     7801 tgctcatcga tgcggcgaac gtgccgttgt ggacggagcg gatcgcgtcg accagctgca
     7861 cggcggtgct gtccttcagc aggaagccca cggccccggc gcgcagcatc cgcagggcgt
     7921 aggcgtccgt gtcgtgggtg gtgagcccca ggatgcgcgt gcccgcggcg tgcccgcccg
     7981 ccacgagccg gcgggtcgcc tcgatgccgt cgaggacggg catgcggacg tccatgagca
     8041 ccacgtccgg gcggagctcg gcgacgcgcg cgacggcctg ctcgccgtcc gcgcagaccc
     8101 cgaccgcggc catgtccggc tgcgcgtcca cgatgcgcgc gaatccgtcc cgcaccaggg
     8161 actggtcgtc gaccacgacg acgcggatga gcgcgggcgc gtcgctcacg gggagctccc
     8221 gccgagcggc gcggtcggcc accgcgcctg cacgacgaac tcgtcgccgc acgcgtaccg
     8281 ggcctggccg ccgtggaggg cgcagcggcg gcggatcgcg gcgaggcccc ggtgctcctg
     8341 cacggggcgt ccccgcaggt cgcgtcccac ggcgttggcg acggacaccg cgagcgcgtc
     8401 gggcgaccac tcgacgcgga ggcgcgcggg ggcgcccgcg ccgtgccgca acgcgttcgt
     8461 cagggattcc tgcacgaccc ggtagacggc ggatcccacg cccggcagga ggggacgcgg
     8521 tgtgcccgcg tcctgcctct cgatgcggag gccggagccg cggaagccct cgacgagggc
     8581 gtcgacgtcg tcccagccgg ggacgggacg gacgtcggcg tcggcctccg tgggggccag
     8641 gagcccccgc acctcgtgca gggcggcgcg gctggtctcg gagatggtgc ggaacatgcg
     8701 ggacacctcg gggctcggcg cggtcgcccg gccgctctcc gcctggacga tgacgctggt
     8761 cagcgtgtgc gccagcacgt cgtgcatgtc gtcgctgatg cgctcgcgct cctcgtaggc
     8821 ggcgatgcgc gtccgcgcgt ccgcgtcgcg ttcggacagc atcgtccgga gctcggcggt
     8881 gcgcacggcc tcggtccggc gccgctcgag cagacccgcc gcccacgcga tcgcgaagct
     8941 cacggacacg agcgcgatga ccatgccgac ggatcccgtg gagcccagct ccccgccggt
     9001 gagggtgcgc gcggcgagga cgaccacgaa gcaggcgccg agggcgaggc ccgcgtgccg
     9061 gaaccggtcg gcggcgtgcg cggacacgga gtaggcggcc accaggagca ccacgtcgcc
     9121 cgggaacagc agcgagctcg tcaccagcat gtgcgccgac gagatcgccg tggccagcag
     9181 cgcggcgacg acgggccgtg cgtggcgcac cgcgagcgtc agcgccatga gggaggacca
     9241 gatccagtcg ggctggccga ggacgcccat gacggcgcac aggacgacgg cagcgcccgc
     9301 gacgacccgg tcgacgtgcg cacgcggact cccccgtcgc atcacgtcct caggctagcg
     9361 gcgagcgcac gcccgatcgc cggcggaggc cctcccgtcg cccccccgtc cacgggtcgt
     9421 cccggtcgcg gcctccgacg atggggggag gacgcggccc cggatgtcac cgggtcgcac
     9481 gatgcgctcg gacggacgcc gctgagatcg tgctcaggag ggatcgcgca cgggctgcgc
     9541 gtcgacgccg caccggccga ggcgcgcgga tccgcgatcc cccggggcaa gtcgaacctg
     9601 tgagggccca cgggccatcg ggatgggtgc ggctcgcacc acgacggtcc gggccgaccg
     9661 gctgggatcc atgcgcgaca acaggaacac aggtggaaca cgatgaacga catcctcgag
     9721 acggagcctc ccgtcatggt cagcccccgg tgggacatgc tcctcgacgc gggcgacgag
     9781 accagcccct ccgtccagac ccagatcgac gcggagttcc gtcgcgtcgt gagcccgtac
     9841 atggccagca gcggctggct ctgcacgctc accatcgaat gcgggacgtt catctgcgcg
     9901 tgtcgctgac ggacgccctc cccggacggg ccgcgctcca cgcgcggccc gtccgctgcg
     9961 cgtcgggccc tgcccgccgt cccgggatga gggagccgac gtgacgatca ccgcggtgga
    10021 gctgtcgctc ctgcaggcgg cccggctgcg cgaacggcgc gcggcgacgc gggccgatgc
    10081 ccgccccgtc cccgagctca cgcgtgcctg gcgcgtcgac gccctcgtcg acgacgggac
    10141 gcacgccgcc tacctcgccg ggcagctgct ggacggcgac gacctcgtgg cgctcctggc
    10201 gggcgacgcg tggaccccgc gggccgcgag cgcggactgg ctcgcccggg tggatccgtg
    10261 gctcgtgcag ccgccggtct ccgcggaggc ctacgcgccg gcgaacggcc acctcgtcgt
    10321 cgaggacacc cgcgtggccg ggctcccctt cgccgccctt ctcggccccg tggtcggagc
    10381 gcagcgcgcc cacctggacg gccgcccgtg gctctcgccc accgcacgcg cggatctcct
    10441 cgacggcctc gcggagcgcc tcgcgaccct cgccctccgg gtcctcatcg cggagctggc
    10501 cgcggatccc gggccggacc gctacgcccg actcgaggcg cggctcgccg accccgcgca
    10561 tcgcgccgcg ttcctctccc gccacccggt cctcgcgcgc gacctcgtca cggcgatcgg
    10621 cagctggcgc gcgcatgtcg cgcgcgtcct cgaccgcctg cacgtcgacc acggggacct
    10681 cgtccgggtc ggcctcgcgc ccgagcggct cgacgccctg gaggccgtgg acctgggctc
    10741 gggcgacccc catgacggcg ggcagtccgt cgccacgctg cgcttctcgg acggccgccg
    10801 gctcgtctac aagccgcgcg actgccgggt cttcgcgctg taccgcgacc tcgtcgacgc
    10861 gctcgcgccc gccctccccg cggagatccg cctgcgcgcg gccgccgtgc tgccgcgcga
    10921 cgggtacggc tgggtcgagt tcgtggcgca cgccgacgac gcctccgccg cgatccccct
    10981 gtcccggcac ctcggccggc tcggctcgct gctcgccgtc gcgcacgtgc tcggcgcatc
    11041 cgacctccac ctcgagaacg tcatcgcctc cgcggacggt cccgtgccca tcgacctgga
    11101 gacgctgatc cagaaccgca gcgaggtcga cggcgaggac gggacggccc tgcgccgggc
    11161 atcgcggatg ctcaacgcgt cggtgctggg cagcggcatc ctcccggtcc agctcaccac
    11221 cggggagggc acgagcatcg acgtgagcgt cagcaccggg ggcctgcacg acgcggggac
    11281 cacggcgacc gtccaccagg tggtggacgc ggccacggac ggcatgcgga tcgaggcgcg
    11341 cgagatgccg gtcggccggt cgcgcaacca gccgccgggg gcgacgctcg cgcgcatccg
    11401 ctccggtcgc gccgccctcg cggacgggta cgcgcgcacg ttccgcgccg tcatcgagct
    11461 ccgggcggag gtccgcgcga tcctgtcggc cgcgccggac atgtcgtcgc ggcacatcgt
    11521 gcgcgccacc cgctcctact ccctgctcct cacggagatg cgccgacccc gcccgctccg
    11581 cagcggcatc gaccgcgacc acctcctccg ccacctctgg acgcgcatcg aggaccaccc
    11641 cgccgatgcc gcgctgatcg aggcggagga gcgtgccctg tggcggctcg acgtgcccct
    11701 gttctccacg cgcatggatg cgcgcgcgct gatcgccgac gatcgggagg tcgcgcccgg
    11761 gcgcttcgcg cggaccacgc gtgaggacgt gctcgaccgg ctcgccgggc tcaccctcga
    11821 cgacctcccc gagtcgctcc ggctgatcga cgagtccgtg ctggcggcga ccgcgacgcc
    11881 cgacggggac gacgaccgtg acgccgcgac cggacggcag gccgcggacg ccgccgcgtc
    11941 acccgcccgc gcaccgcgca tggacgacga cgccctgcgg gaggcggcac gcggccaggc
    12001 ccgcctcctc ctcgactccg ccgtcctcgg tcgggacgac gccacgtgga tcggcctcag
    12061 cagcagcctc gacagcagcg gcctcgagta ccgccccgcg ggacccaccc tgtacgacgg
    12121 gctggcgggg atcgcgttcg ccgcgaccca cgcgcacggc gtgctgcccg acctcgggct
    12181 cgacgacctg gccggccggg cgatgcacgc ggtcacggcg atcctcgacg actggacgcg
    12241 gggcctcatt gacctcccgg tgggcgccta cagcggcgcc gccgggctgc tcttcgcgct
    12301 cgcgcaccac gacgcacggg tcggcgacga cgcgcaccgc gacctccggg cggcggccgt
    12361 ccgacggctc ggcgaggtcg cccacgagga cacgcacctg gacgtgatgg cgggcgtcgc
    12421 cggggcgtgc gctgtggtcg cggggctgcc cgagggggcg accgagggcg gccgcgcgac
    12481 gctgcgagcg ctggtcggac gcctgatgag cacggcggtc gaggtggacg gcggcgccct
    12541 cgtctgggag accggggccg agcgggcgcg gttgggcggg ttctcgcacg gcgcatccgg
    12601 cgtcggctgg gcgctcgccc gcaccgccgg cgtgctggac gacgaggcga tcgccgatgc
    12661 ggccgtgcgc gccctgcgct tcgacgacgc gctgttcgac ccgtcccgcc gccgctggcg
    12721 cgacgcgaga ccggaggcgc gatccgcgac cggatccttc cccgcgcact ggtgccacgg
    12781 caccgccggg atcgcgatgg cccgcgcgga cgcggccgcg gcgctccgca gaacggatct
    12841 cctcgagctg gctctcgtcg gcgcccggga gacggcgtcc gacgcgctcc cctccgacga
    12901 ttccctgtgc cacgggacgc tcggcaacct catcgcggtg cgcggggtga cccggcggat
    12961 cggcggcgag gccgggctcg cggagtaccg cgaccgcgcg ctgcgacgcg tcctccgcgc
    13021 cggcccacgc agcggtctgc ccgaaggggt gaccagcgtg cggggcctca tgctcggcac
    13081 ggccggcgcg ctctacgcgc tgtgccggga gctcgacccc gggatcccgg acgcgctgct
    13141 gctggagggg ccgcgctgac ggtcgtcgac ggggttcgcg cggggtggcc cgggcggccg
    13201 tcgtggggcc gcccggggac gggtcacatc gtgttccagt ggttcttccc gttggcgtcg
    13261 gggccgtgcc cgccgcactt gtagctgcga ccgttggccg cctgggcgac ggtgccgacg
    13321 tcggcgttgg agcagaaggc gccgggcttg atgagcccgg tctgctgcgc cggcgcgggt
    13381 gccggggccg cgggagccgg tgcgggagcg ggcgcgacgg gcgccggagc gggagccgcg
    13441 ggctgcggcg cgggcgcaac cgtcggcgcg accgtgggct cgggcgtcgg ggtcggcgcg
    13501 ggcgcgagca gcgtgagcag cgtgagcgtc acagtggatc cggcgtcgac gcgcgatccc
    13561 gcgaccgggc tctgcgacac cacggtcatg ccgtcggtga cgctcggcac cccgccggac
    13621 tcgagcacgt actggacgac gtagccggcc tcgcgcagga gcgcgcgggc gtccgtcgcg
    13681 gacttcgcgc tgacgtcctc gacgacgtgg accaccgggg tcggggtcgc cgacggcgtc
    13741 ggggtggagg tcggcgtcgg cgaggcgctc gcgctgatcg cgtccacctg acgcggaccc
    13801 gacgtcgagg cggccacggg cacgacggcg cccatgacga ggagcaggat cgccccggcc
    13861 gcggtcgcgc tgctgcgcgg gcgggtggcg agggcgggga tccagctgcg gcggccggtg
    13921 agcagcggat acaggcccgt cgccagggcg accagcccga gggagacgaa catgccgccg
    13981 aatccgccca tggccgtgat gatcagcacg gccagcgcga cgacggacgt gacgacccac
    14041 gtcgtggcgg ggtgccggct cggccgggtg tcggcgatga cgggagccac cgccttcggc
    14101 gcgacctgcg ccgtcggggc gggccatgcc gctgccgcaa cggggatcgc ggcggtcgcc
    14161 gccgcgcgct cggccttggc ccgcgcggcc gcctcgcgct ccgcggcctt ggcctgcatc
    14221 gccgcctccc gctgcgcgac cttcgcggcc cgctgctgct cggcgacggc tgcgcgctcg
    14281 gcctggatcc gcgcggcatc cgcggcgcga gcggccttcg cctgttcggc ctgctgcgtg
    14341 gcggcgacgg cggccagcgc cgcggcgctc ggcgcctgcg cctggggtgc ggcgggctgg
    14401 accatcgggg cgacgtgctg cgtccacacg gcgccgtccc agtagcggag ctggccggat
    14461 ccgtcgggga accagccggc gggagcggcg gaggggacgt cggacatggt gctcctcggg
    14521 tgcgtgccgc ggcgaagggg taggcggcag gtggtgccgt cgagtgacga cgcctgaggc
    14581 tatgagcgcg ctcccacggg cgtaagccct cgtgtggggg tgaatggggg gggcgggact
    14641 actgggatcc gtcggcccga cgggccacgt ctggatccat cgcatcaaag ccctcgtccg
    14701 cgcccggtcg acctccgcca ggatccgatc tgccgtctcc tgcggcgact cgtgttccca
    14761 aaaacgcagg acgatccgtg aggagacgcc gaggggcgat cgcgtccgtg aggctttcgc
    14821 gactttgctt gagcatcagg atccactaat cagcagccgc gttcagcgcg cccagtactc
    14881 ccgcgccgac gtatctgacg catccgcgac cgagtcagct aggcgccgcc gggtgaacgc
    14941 gatacggtgc ggtcatgtcg attgatgtgc tactcgggcg ctctaccgtt ccgatcgacg
    15001 aggcggtgtt ccgtgccttg ctcgataact ctgtcgccgg aacgtacgct gactattcct
    15061 acgcactgga gcgcggaaat atacgtttta ccacattggt aaagttggca cgcaaaggtg
    15121 agataccgta ttcattgttc tttgcgcctc ttcccgtagt ggaggcacaa gtcggcgcaa
    15181 aaacggaaaa actactggcc ggcacgagta agaaaacatt ttccctaggg tcaagaagcc
    15241 gcgtagaatt acgagacatc gagcttatca ttaaagacct actgcgcaag caggagttac
    15301 taaagcggca cgaccagagc cttgttgaaa accgcgtcgt aggaatttta cacaagcccg
    15361 gcgccacgcc ggatgcggac gcgaacaagt taatggcagc aatagaccta cgcccgcaag
    15421 acttgcgtaa gtgtcgcacg aaagagaagg cgctcgatct aatgatcgag cggttggaag
    15481 cgaagcagat ccttgtgtcg cggagcgtcc aacactatat gcctcaacgc ctgacgcacg
    15541 tggagttcag cggaatgacg attcgcgata agatagtacc gttcattttt ctggccggtg
    15601 gtgaacataa cgactaccag gaaccagtcg gtaggaccat ttttaccctt gcactgatga
    15661 cagtacttat cggtcgcaga atcttcgccc caatgacttg ggatggggca agcgtgggaa
    15721 ccgaagtcgg aagagagtac gacatcgccg gggcgatgct tatgcctcgc gaccagatga
    15781 aggagctcgc gccgacctcc ctagaagaca tgaaagcaat ttcaagcgaa tttaaagtca
    15841 cggccagcgc ggtcacggtc cgcgcgatgc gcctttccct catcacagga gagaccgcca
    15901 ccgcatatct cgacgatttg cgactcgatt acaaccagaa caagcagtca aagcccatga
    15961 atcagccact gccggagaac gctatcagaa agtataatgg taatgaactc actaagcgaa
    16021 tgctcgatgc gctgagtagc aacagcatct caactagtga cttctgccgc tctgtctgct
    16081 taaaccgcat caagccaacg cagatagatg acctgagaag ggcgctgtcg tgaacatgtt
    16141 cggaacccgc tatgtcattg acacgaacgc gcttatccaa atggggcgag agcgccgcga
    16201 aagtaatttt ttcagcctga acgcagtcat tccaagcgag gtactgcatg aggccgaagg
    16261 gttccccgac tacgcgcaac tccttacttt cgacttcgca acaactccga gggtccttga
    16321 atacttgact gacgtaatga atacgattca cgccgaagat acaagtctcg tcgacctcta
    16381 caagaacctt ggtggcgcag atccgctcgt ggtggcgtgt gcgcttactg ggaaggaaat
    16441 cgacagccag tatctggatg cgcccaagtg ggtcattgtc acgggggacg aagcggtatc
    16501 ggcgaaggct cgcgaattta atctcgacgt tgtcgacgtt accaccttcg cagcacttat
    16561 cgatgaggcg caggcaacgg caacggcaac ggcaacggca acggcaacgg caacggcaac
    16621 ggcaacggca acggcaacct tcgatcgcga ctgacgctag ctatgatgac aaaatcgcct
    16681 cacgctctcc gcaggttgca tggcagcaga cctcgctctc gttgcatctc ctgtgaggaa
    16741 atgtgcaaga tcacgctatg gacgcttgtc gacggaacgc aatagctcgc ggatacctct
    16801 caaggcctaa gaagcaccga agaccgcctc agcagagtca agacagcagt gaaactcggg
    16861 gaagcacgcg attcaggtcg gtgcgtcgac catggagttc accgcaacga tgcctgcgta
    16921 catacgacga atgccccggc cggacccatc aggtccttcc gaggcatgtc cgtcgggctg
    16981 acaggatttg aacctgcgac cccttgaccc ccagtcaagt gcgctaccaa gctgcgccac
    17041 agcccgctgt cccatcgctg ggcaactcgt agagcctacc gcatcggcag cactgctccg
    17101 gcacgcgcgg ggccccggat caggccggcg caccgcccgg gcgacccgga gctgacgggt
    17161 caggcgcacc gggagcagcc acccgccccg gcttcgggaa cgcgtcccgc atgtggtcgc
    17221 tccgcaggat gtccgctacc ccgatcagca gcagcgagaa cacgatctgc tcgatgacca
    17281 tccagagcgg gtacaggccc gggatcgcgg cgaccaccag ggtcacgatg gggaagatct
    17341 ggctgaagag gcgcaggcgc gagtacgccc accagtagcc ggccgaggcg cgccaggcga
    17401 agtagtagag cgtgatggtc atcgcgagca ccacgaagga gcggaaccac acggcgggcg
    17461 cgatcgcgat gccgtcggag gcgagggtca gggcgatggc cacggcggtc gcgccgacgg
    17521 cggtctcggc gatgaggatc caccggatcc agcggaacgc ccgcgtcgtc cacgggtggt
    17581 cgcgcatgtc ctccgcgatg acgtggcccg cctggcgtcc ggcggcgatc cgatcgaggc
    17641 ggctgagcag ctggtccacc ggtgcgatcc tccgtgtctc gtgagcgggc gtcggatgcg
    17701 cccgcatcag ggtacggcgt gacgcctgga gccagccgcg aacacgggga gcggcgcgat
    17761 ccggacaggc gacgcgggca cccgcccgcg gccggcggat cccccgcatg acaccccgtg
    17821 acgccccgcg tcgtcacgcg gggcaaccgc gcgtcacacc cctcgccagc ccgcgcagca
    17881 cgcccctacc gtggccccac cgcgaggcgc ggcaccggtc gcgccccctt cacgagaggt
    17941 acaggacatg accctgatcg accgcgagcc ccgacccgca tccggctccc ccacgcccgc
    18001 ccgcggcacc gcacccgcga agacggaccg cccgcgcccc gctcccctcg gcgacgcgcc
    18061 cgtcgaccgc tggaagggcg cgccccgtcc caccacgccg gccgcgtgga tcgcccgcgc
    18121 ccgcgaggtc gccgacatcc tcgccgtcga ccaggtcgag cgcgaccgcg ccggagcgag
    18181 cccgcaccag gaggtggcgc tcctcaagca cgccggcctc gtcacgctgc tcggacccgc
    18241 ggagcacggc ggcggcggcc agacctggga caccgcgtac aaggtgatcc gcgcggtcgc
    18301 ccgcggcgac ggatccatcg gccagctcct cggctaccac tacctctggg cgtgggccgc
    18361 gcggctcgtc ggcaccgatg cgcagatcga ggcggtcgag aagctcgcca cgaccgggaa
    18421 cctgctcttc ggcggcgccg tgaacccgcg cgactccgac ctcgtcatcc gcgaggacgg
    18481 cgacgacctg atcttctccg gccgcaagtc gttctcgacg ggcggcgtcg tctccgacct
    18541 cacggtgctg gagggcgtga tcgagggcac cgacacgcac gtgttcgcga tcgtgccgac
    18601 ggaccagccg ggcatcgtgt tcggccacga ctgggacagc ctcgggcagc ggctcacgga
    18661 gtccggctcg gtggagatcc gcgacgtgcg ggtgccgtgg accgatgcgg ccgggttcgt
    18721 cgacaaggtc ttccagccgc tcgtctacgg cacgctcaac gtgcccgcga tccagctggt
    18781 gttcgcgaac ttctaccagg gcatcgcgga gggcgcgctc gagacggccg ccgcgtacac
    18841 gcgcagcacc acccgagcct ggccgtacgg cggcgacgac aaggagcgcg cgaccgacga
    18901 gtggtacgtc ctcgagggct acgggcagct gcagtcgaag ctgtgggcct cggaggcgct
    18961 gctggatcgg gtgggcgccg agatcagcgc cgtgctgcac gcgccgcgcg agaagctcac
    19021 ggagcggaag cgcggcgaga tcgccgtgcg cgtcgcggcg gccaaggcgc gcatcgcgga
    19081 ggacgggctg gaggtcggca cgcggatcct cgagctcacg ggtgcgcgcg cctcctcctc
    19141 gaaggccggg ctcgacatct tctggcggaa cctccgcacg cacacgctgc acgacccgat
    19201 cccctacaag cgccgcgagg tgggccggca cgtgctgctc ggcgagatcc cggagccgac
    19261 ctggtacacg tgatccgcat ccagcccccg acgacggacg gcgccgaccc ccaagaggga
    19321 tcgacgccgt ccgtcgtgct gcgagccgag gcccgcggaa gccgactagc gcttccgctt
    19381 ctcccgcacg cgcatgttga cgatgatcgg gctgccctcg aagccgtaga tctcgcgcag
    19441 gcgacgctgg atgtagcggc ggtactgcgg gtcgaggtac ccggtcgtga agagcacgaa
    19501 tgtcggcggc cggctcgagg cctgcgtgcc gaacaggatg cgcggctgct tgccgccgcg
    19561 cacggggtgc gggtgggcgg ccgtgagctc ggcgaggaac gcgttgaact tgcccgtcgc
    19621 gatgcgggtg tcccacgact ccagcgccgt ctcgagcgcc ggcacgagct tctccatgtg
    19681 gcggccggtg cgggccgaga tgttgacgcg cggcgcccac gacacgtgcg cgaggtccgt
    19741 ctcgatctcg cgctcgaggt agcggcggcg ctcgtcgtcg aggaggtccc acttgttgaa
    19801 cgcgagcacg agcgcgcggc ccgactcgag caccagctcg atgatgcgga tgtcctgctc
    19861 gctgatgacc tcggagacgt cgatcatgac gaccgcgacc tccgccttct ccagcgcggc
    19921 gctcgtgcgg agcgacgcgt agaagtcggc gccctgggcg aggtgcatgc ggcggcggat
    19981 gccggcggtg tcgacgaagc gccacacctt gccggcgatc tcgacctgct cgtcgacggg
    20041 atcacgcgtg gtgccggcga gctcgttgac gaccacgcgc tcctcgcccg cggccttgtt
    20101 gagcaggctc gacttgccga cgttcgggcg gccgaggatg gcgacgcggc ggggtccgcc
    20161 gacctcctcc ttggcgacct tggagacgag cggcagggtc ttcagcacga ggtcgagcag
    20221 gtcggccacg ccgcggccgt gcagcgcgga gacggggtgc ggctcgccga ggccgagcga
    20281 ccacagcgag gcggcgttcg gctcctggcg cgcgtcgtcg accttgttgg ccgcgaggat
    20341 caccgtcttc ttggtcttgc ggagcaggcg gacgacgtgc tcgtccgtgc tcgtggcgcc
    20401 cacgttggcg tcgacgacga agagcacggc gtcggcgagg tccatcgcga tctcggcctg
    20461 catggccacg gacgcgttga tgcccttcgc gtcgggctcc cagccgccgg tgtcgaccag
    20521 cgtgaaccag cggcccgcgt actcggcctt gtaggagacc cggtcgcgcg tgacgccggg
    20581 ggtgtcctcg accacggcct cgcggcggcc gaggatgcgg ttgatgagcg ccgacttgcc
    20641 gacgttcggg cggccgacga ccgcgagcac gggcagcgcc ggcaggtacg tgacctggtc
    20701 ggggtcgtcc gtggccgact cgaggacctc gaggtcctcg tcgtccagct cgtagtcctc
    20761 gagcccggcg cggagcgtct gcgcgcgctg tgcggccagc tcctcgtcga tgctcgacag
    20821 gcgctcgtgg agcccgctgt cgagctcggg gaagtcgtcg tcgtgatcag ccatgttgtt
    20881 cctctggcgt gtcggcccgt cgccgggccg cgcctcaatc tgttcgtgcg tgaacgagat
    20941 cgaccaccgc ctggacggtc tggtcgaagt cgatgtccgt ggagtcgatg gtggtcacac
    21001 catctgcggc gttcatgaaa tcgacgacct gcgagtcggc ccgatcccgg gaggcgagtg
    21061 attcgccgac cgcggctgcc gactgggtcg acgtctccgc ggaacgcctg ctcatcctag
    21121 cttccgggga ggccgtcagc agaatgcgca cctgggcgtc cggcgccacg acggtggtga
    21181 tgtcgcggcc ctcgaccacg atgccgggct tgtcgctcga cgccatgagc gagcggaaca
    21241 gctccaccat gtagtgccgc acctcgggca cgcgcgccac gtggctcacg acggcggaga
    21301 cgcggggctc gcggatcgcc tcggtgacgt cggtgccgcg gacgctcacg cgcgtctggt
    21361 cggggtcgat cgcgatgtcg tagtcgaacc cctcgatgag gctcgtgacg gtggcgggat
    21421 cctcggtgtc gacgccgctc tccagcgcga accagctgag cgcgcggtac gcggcgcccg
    21481 tgtcctggta gtcgaagccg agggcgcgcg cggcggcgcg gctcacgctc gacttgccgc
    21541 tgccggcggg gccgtcgacg gcgacgaccg tgcggttcag cgtggcgtcc accaggagga
    21601 cgtcctccag cgggtcgggt gcggtcgggt cgggggcgtt cacagcgtct ccggtcatcc
    21661 ggcgatcctc cagtcacgtt cttcgagccg cgcgaccagg cggtcgcggg cctcgggcag
    21721 cacggcgatc tccacgagac ccacctgcgc gccctgcgag tgctcgaggc gcaggtcctc
    21781 gatgctgacg tcggcggcgc cgacgtcgct gatcagcgcg gccagctggc cgggccggtc
    21841 gtcgatcatc acggtgatgg cggcgaagcg ccggtcctgg ccgtgcttgc cggggatgcg
    21901 cgcgacgccc gcgttgcccg cgtggatccg ctcggctacg cgcagccgcg ccccctgcgc
    21961 gtcgacgtcg tccagcgcgt cgatgacgtc gtcgaggtcg gtgcggagcg cctggaggat
    22021 cggcacgacg cgggcggcgt tggcgccgag gatctgcacc cacagcgcgg cgtcgctcga
    22081 cgcgatgcgc gtggtgtcgc ggagcccctg gccggagagg ccgagcgctg ccgcgtcgcc
    22141 gtcggccagc cgcgacgcca gcaggctcgc gacgacctgc ggcacgtgcg agacgagcgc
    22201 caccgaggcg tcgtgctcct ccgccgtcat ctcgatcggc acggcgccga ggtcgaggat
    22261 cagctgctcg acgggcgcgc cggctgcgta cgtgatgccg tcgtggcccg cgatgaccca
    22321 ggggcggccg aggaagaggt cgcccgtcgc ggagacgggg ccgccgcgct cgcgcccggc
    22381 gagcgggtgg gagccgaggt agcgcgagag gtcggcgccc atcgcccgca gctccgcgag
    22441 cggcgcggcc ttcacgctcg cgacgtcggt gacgagggcg tccggatgcg cggcgagctc
    22501 ggccgcgacc acgcgcgcgg tcacgtccgg cggcacgcag acgacgacga gcgacggccg
    22561 gtcgggcacg acggcgatgt cggcgatgcg ccccgcgccc atgtccgccg cgagccgcag
    22621 cgtggtcggc gacgcgtccg cgagcaccac gtccacgccg cgcgcggaga gcccgaggcc
    22681 gatgctcgtg ccgaggagcc ccgtgccgac gatgcggacg gtcccctgca cgcgcgtgtc
    22741 ggtcgcggcg gccgcgcccg cggcctcgct cactcgccgt cctcgcggtc cgcgtccccc
    22801 tgcgcctcgg cgtccgcgct cgcaccctgc ggggtcgcgg gtccggcctg cgcgcgggcc
    22861 tcgcgcgaga tggtgaggag ctggccgagc tcgtcggagg tgaggtcgcg cacgcggccc
    22921 accccgaggg atccgaggtg cagcggcccg aactggcggc gcacgagctc ctcgaccggg
    22981 tggccgacct cgtcgagcat gcggcgcacg atgcggttgc ggcccgagtg cagcgtgatc
    23041 tccacgagcg tctggtcgcc gccgcccgag aggatgcgcg cccgatccgc ctggatcggc
    23101 ccgtcctcga ggtccacgcc ctgcgtgagg cgctggatcg tctgcggggt gacgcgtcc
//
